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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117123268
log Bayes Factor = 19.5843
Chromosome 14   position 76,719,166  (GRCh37) Explore rs117123268 on Ensembl!
Variant rs117123268 is part of Cluster X0020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
N10-N16 Renal tubulo-interstitial diseases
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.989 0.011 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.988 0.012 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.986 0.014 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.985 0.015 0.000
E70-E90 Metabolic disorders
0.982 0.018 0.000
I60-I69 Cerebrovascular diseases
0.978 0.022 0.000
H65-H75 Diseases of middle ear and mastoid
0.978 0.022 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.975 0.025 0.000
E10-E14 Diabetes mellitus
0.974 0.026 0.000
Chapter XX External causes of morbidity and mortality
0.972 0.028 0.000
Z98 Other postsurgical states
0.969 0.031 0.000
A30-A49 Other bacterial diseases
0.968 0.032 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.968 0.032 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.963 0.037 0.000
H43-H45 Disorders of vitreous body and globe
0.961 0.039 0.000
Z95.2 Presence of prosthetic heart valve
0.958 0.042 0.000
N13 Obstructive and reflux uropathy
0.957 0.043 0.000
J09-J18 Influenza and pneumonia
0.957 0.043 0.000
T82.1 Mechanical complication of cardiac electronic device
0.955 0.045 0.000
Z90.2 Acquired absence of lung [part of]
0.951 0.049 0.000
E10 Insulin-dependent diabetes mellitus
0.948 0.052 0.000
Z98.0 Intestinal bypass and anastomosis status
0.943 0.057 0.000
I67 Other cerebrovascular diseases
0.942 0.058 0.000
S40-S49 Injuries to the shoulder and upper arm
0.936 0.064 0.000
H43 Disorders of vitreous body
0.933 0.067 0.000
N25-N29 Other disorders of kidney and ureter
0.932 0.068 0.000
Z93 Artificial opening status
0.932 0.068 0.000
O20 Haemorrhage in early pregnancy
0.931 0.069 0.000
H30-H36 Disorders of choroid and retina
0.929 0.071 0.000
A41 Other septicaemia
0.928 0.072 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.926 0.074 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.926 0.074 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.924 0.076 0.000
E86 Volume depletion
0.924 0.076 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.923 0.077 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.921 0.079 0.000
H65 Nonsuppurative otitis media
0.919 0.081 0.000
N00-N08 Glomerular diseases
0.914 0.086 0.000
B35-B49 Mycoses
0.910 0.090 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.909 0.091 0.000
I67.8 Other specified cerebrovascular diseases
0.909 0.091 0.000
I05-I09 Chronic rheumatic heart diseases
0.905 0.095 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.904 0.096 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.902 0.098 0.000
J20-J22 Other acute lower respiratory infections
0.902 0.098 0.000
Z95.4 Presence of other heart-valve replacement
0.899 0.101 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.896 0.104 0.000
E87.2 Acidosis
0.893 0.107 0.000
Z93.2 Ileostomy status
0.893 0.107 0.000
J18 Pneumonia, organism unspecified
0.891 0.109 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.887 0.113 0.000
S42 Fracture of shoulder and upper arm
0.885 0.115 0.000
E20-E35 Disorders of other endocrine glands
0.883 0.117 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.881 0.119 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.880 0.120 0.000
O43 Placental disorders
0.875 0.125 0.000
H65.3 Chronic mucoid otitis media
0.874 0.126 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.866 0.134 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.866 0.134 0.000
H43.3 Other vitreous opacities
0.863 0.137 0.000
N13.3 Other and unspecified hydronephrosis
0.861 0.139 0.000
I30-I52 Other forms of heart disease
0.861 0.139 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.860 0.140 0.000
O20.0 Threatened abortion
0.860 0.140 0.000
A49 Bacterial infection of unspecified site
0.860 0.140 0.000
Chapter XXII Codes for special purposes
0.860 0.140 0.000
S80-S89 Injuries to the knee and lower leg
0.857 0.143 0.000
S42.2 Fracture of upper end of humerus
0.857 0.143 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.857 0.143 0.000
H55-H59 Other disorders of eye and adnexa
0.854 0.146 0.000
Chapter VI Diseases of the nervous system
0.854 0.146 0.000
O36 Maternal care for other known or suspected foetal problems
0.854 0.146 0.000
O80-O84 Delivery
0.853 0.147 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.850 0.150 0.000
H43.1 Vitreous haemorrhage
0.849 0.151 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.846 0.154 0.000
Z97 Presence of other devices
0.845 0.155 0.000
O00-O08 Pregnancy with abortive outcome
0.844 0.155 0.000
E10.3 With ophthalmic complications
0.842 0.158 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.840 0.160 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.840 0.160 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.839 0.161 0.000
S42.20 Fracture of upper end of humerus (closed)
0.837 0.163 0.000
N99-N99 Other disorders of the genitourinary system
0.837 0.163 0.000
Z86 Personal history of certain other diseases
0.835 0.165 0.000
Z90.8 Acquired absence of other organs
0.835 0.165 0.000
E10.5 With peripheral circulatory complications
0.833 0.167 0.000
E11 Non-insulin-dependent diabetes mellitus
0.831 0.169 0.000
J18.1 Lobar pneumonia, unspecified
0.831 0.169 0.000
I34 Nonrheumatic mitral valve disorders
0.830 0.170 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.829 0.171 0.000
N10 Acute tubulo-interstitial nephritis
0.827 0.173 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.826 0.174 0.000
H74 Other disorders of middle ear and mastoid
0.824 0.176 0.000
Z90.0 Acquired absence of part of head and neck
0.824 0.176 0.000
E87.0 Hyperosmolality and hypernatraemia
0.822 0.178 0.000
E16 Other disorders of pancreatic internal secretion
0.822 0.178 0.000
H33 Retinal detachments and breaks
0.822 0.178 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.821 0.179 0.000
H66 Suppurative and unspecified otitis media
0.821 0.179 0.000
T86 Failure and rejection of transplanted organs and tissues
0.820 0.180 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.817 0.183 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.815 0.185 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.813 0.187 0.000
H53-H54 Visual disturbances and blindness
0.812 0.188 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.810 0.190 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.809 0.190 0.000
H73 Other disorders of tympanic membrane
0.809 0.191 0.000
T87 Complications peculiar to reattachment and amputation
0.809 0.191 0.000
H36 Retinal disorders in diseases classified elsewhere
0.809 0.191 0.000
O47 False labour
0.808 0.192 0.000
E87.7 Fluid overload
0.806 0.194 0.000
I26 Pulmonary embolism
0.806 0.194 0.000
H18 Other disorders of cornea
0.805 0.195 0.000
A41.9 Septicaemia, unspecified
0.805 0.195 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.804 0.196 0.000
E10.2 With renal complications
0.801 0.199 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.801 0.199 0.000
H90-H95 Other disorders of ear
0.798 0.202 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.798 0.202 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.797 0.202 0.000
S00-S09 Injuries to the head
0.797 0.203 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.797 0.203 0.000
W50-W64 Exposure to animate mechanical forces
0.797 0.203 0.000
W00-W19 Falls
0.796 0.204 0.000
B37 Candidiasis
0.795 0.205 0.000
O43.1 Malformation of placenta
0.795 0.205 0.000
I69 Sequelae of cerebrovascular disease
0.794 0.206 0.000
E83 Disorders of mineral metabolism
0.793 0.207 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.790 0.210 0.000
J22 Unspecified acute lower respiratory infection
0.789 0.211 0.000
V10-V19 Pedal cyclist injured in transport accident
0.788 0.212 0.000
N28.1 Cyst of kidney, acquired
0.787 0.213 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.785 0.215 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.785 0.215 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.784 0.216 0.000
I67.2 Cerebral atherosclerosis
0.783 0.217 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.781 0.218 0.000
O23 Infections of genito-urinary tract in pregnancy
0.781 0.219 0.000
I78 Diseases of capillaries
0.780 0.220 0.000
O42 Premature rupture of membranes
0.779 0.221 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.779 0.221 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.779 0.221 0.000
N72 Inflammatory disease of cervix uteri
0.779 0.221 0.000
H34 Retinal vascular occlusions
0.777 0.223 0.000
I51 Complications and ill-defined descriptions of heart disease
0.776 0.224 0.000
Z90.7 Acquired absence of genital organ(s)
0.776 0.224 0.000
H71 Cholesteatoma of middle ear
0.775 0.225 0.000
E27 Other disorders of adrenal gland
0.775 0.225 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.773 0.227 0.000
I34.0 Mitral (valve) insufficiency
0.773 0.227 0.000
T82.3 Mechanical complication of other vascular grafts
0.772 0.228 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.770 0.230 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.770 0.230 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.769 0.231 0.000
E16.2 Hypoglycaemia, unspecified
0.769 0.231 0.000
V80-V89 Other land transport accidents
0.769 0.231 0.000
Z95.1 Presence of aortocoronary bypass graft
0.768 0.232 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.768 0.232 0.000
I74 Arterial embolism and thrombosis
0.766 0.234 0.000
Z98.1 Arthrodesis status
0.765 0.235 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.765 0.235 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.763 0.237 0.000
O03 Spontaneous abortion
0.763 0.237 0.000
Z88.5 Personal history of allergy to narcotic agent
0.762 0.238 0.000
Z99.1 Dependence on respirator
0.762 0.238 0.000
S60-S69 Injuries to the wrist and hand
0.761 0.239 0.000
H69 Other disorders of Eustachian tube
0.760 0.240 0.000
J20 Acute bronchitis
0.760 0.240 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.759 0.241 0.000
Z89 Acquired absence of limb
0.759 0.241 0.000
H33.0 Retinal detachment with retinal break
0.759 0.241 0.000
Z29 Need for other prophylactic measures
0.759 0.241 0.000
H80-H83 Diseases of inner ear
0.756 0.244 0.000
N04 Nephrotic syndrome
0.756 0.244 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.755 0.245 0.000
B95-B98 Bacterial, viral and other infectious agents
0.755 0.245 0.000
J40-J47 Chronic lower respiratory diseases
0.754 0.246 0.000
Z93.0 Tracheostomy status
0.754 0.246 0.000
I08 Multiple valve diseases
0.754 0.246 0.000
I05 Rheumatic mitral valve diseases
0.753 0.247 0.000
J95-J99 Other diseases of the respiratory system
0.752 0.247 0.000
J18.9 Pneumonia, unspecified
0.752 0.248 0.000
Z90.3 Acquired absence of part of stomach
0.750 0.250 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.750 0.250 0.000
O20.8 Other haemorrhage in early pregnancy
0.748 0.252 0.000
G62 Other polyneuropathies
0.747 0.253 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.746 0.254 0.000
N13.6 Pyonephrosis
0.746 0.254 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.746 0.254 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.745 0.255 0.000
B49 Unspecified mycosis
0.745 0.255 0.000
Chapter XI Diseases of the digestive system
0.745 0.255 0.000
H60-H62 Diseases of external ear
0.744 0.256 0.000
O30 Multiple gestation
0.744 0.256 0.000
E11.2 With renal complications
0.743 0.256 0.000
Y40 Systemic antibiotics
0.743 0.257 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.742 0.258 0.000
M05-M14 Inflammatory polyarthropathies
0.742 0.258 0.000
A49.8 Other bacterial infections of unspecified site
0.741 0.259 0.000
H21 Other disorders of iris and ciliary body
0.740 0.260 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.740 0.260 0.000
Z90.5 Acquired absence of kidney
0.739 0.261 0.000
I34.1 Mitral (valve) prolapse
0.738 0.262 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.737 0.263 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.737 0.263 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.737 0.263 0.000
E83.1 Disorders of iron metabolism
0.736 0.264 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.736 0.264 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.736 0.264 0.000
O82 Single delivery by Caesarean section
0.734 0.266 0.000
J10 Influenza due to identified influenza virus
0.732 0.268 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.730 0.270 0.000
M80-M85 Disorders of bone density and structure
0.729 0.271 0.000
I27 Other pulmonary heart diseases
0.729 0.271 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.728 0.272 0.000
S10-S19 Injuries to the neck
0.727 0.273 0.000
Z97.8 Presence of other specified devices
0.727 0.273 0.000
Z81 Family history of mental and behavioural disorders
0.727 0.273 0.000
O24 Diabetes mellitus in pregnancy
0.726 0.274 0.000
E10.4 With neurological complications
0.725 0.275 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.725 0.275 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.724 0.276 0.000
N11 Chronic tubulo-interstitial nephritis
0.723 0.277 0.000
J60-J70 Lung diseases due to external agents
0.723 0.277 0.000
H36.0 Diabetic retinopathy
0.723 0.277 0.000
E40-E46 Malnutrition
0.722 0.278 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.722 0.278 0.000
H54 Blindness and low vision
0.721 0.279 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.721 0.279 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.721 0.279 0.000
I73 Other peripheral vascular diseases
0.719 0.281 0.000
I72 Other aneurysm
0.719 0.281 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.718 0.282 0.000
Z90.1 Acquired absence of breast(s)
0.717 0.283 0.000
I65.2 Occlusion and stenosis of carotid artery
0.717 0.283 0.000
Z99.2 Dependence on renal dialysis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.283 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.716 0.284 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.716 0.284 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
Z97.0 Presence of artificial eye
0.715 0.285 0.000
I07 Rheumatic tricuspid valve diseases
0.714 0.286 0.000
O03.9 Complete or unspecified, without complication
0.713 0.287 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.713 0.287 0.000
H44 Disorders of globe
0.713 0.287 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.712 0.288 0.000
N15 Other renal tubulo-interstitial diseases
0.712 0.288 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.712 0.288 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.712 0.288 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.711 0.289 0.000
J90-J94 Other diseases of pleura
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.710 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.289 0.000
B65-B83 Helminthiases
0.710 0.289 0.000
B50-B64 Protozoal diseases
0.710 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.710 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.289 0.000
A75-A79 Rickettsioses
0.710 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.289 0.000
A65-A69 Other spirochaetal diseases
0.710 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.289 0.000
A15-A19 Tuberculosis
0.710 0.289 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.709 0.290 0.000
J14 Pneumonia due to Haemophilus influenzae
0.709 0.291 0.000
O36.9 Maternal care for foetal problem, unspecified
0.708 0.292 0.000
J44 Other chronic obstructive pulmonary disease
0.707 0.293 0.000
H66.9 Otitis media, unspecified
0.707 0.293 0.000
Z22 Carrier of infectious disease
0.707 0.293 0.000
O45 Premature separation of placenta [abruptio placentae]
0.706 0.294 0.000
O44 Placenta praevia
0.706 0.294 0.000
O41 Other disorders of amniotic fluid and membranes
0.706 0.294 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.706 0.294 0.000
O33 Maternal care for known or suspected disproportion
0.706 0.294 0.000
O31 Complications specific to multiple gestation
0.706 0.294 0.000
O40 Polyhydramnios
0.706 0.294 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.706 0.294 0.000
B35 Dermatophytosis
0.706 0.294 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.705 0.295 0.000
E10.1 With ketoacidosis
0.704 0.296 0.000
S82 Fracture of lower leg, including ankle
0.704 0.296 0.000
E85 Amyloidosis
0.704 0.296 0.000
E84 Cystic fibrosis
0.704 0.296 0.000
E79 Disorders of purine and pyrimidine metabolism
0.704 0.296 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.704 0.296 0.000
E74 Other disorders of carbohydrate metabolism
0.704 0.296 0.000
E73 Lactose intolerance
0.704 0.296 0.000
E72 Other disorders of amino-acid metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E70 Disorders of aromatic amino-acid metabolism
0.704 0.296 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.704 0.296 0.000
M84 Disorders of continuity of bone
0.704 0.296 0.000
B15-B19 Viral hepatitis
0.703 0.297 0.000
J30-J39 Other diseases of upper respiratory tract
0.703 0.297 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.701 0.298 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.701 0.298 0.000
T79-T79 Certain early complications of trauma
0.701 0.299 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.701 0.299 0.000
H70 Mastoiditis and related conditions
0.701 0.299 0.000
H68 Eustachian salpingitis and obstruction
0.701 0.299 0.000
H67 Otitis media in diseases classified elsewhere
0.701 0.299 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.701 0.299 0.000
H57 Other disorders of eye and adnexa
0.701 0.299 0.000
O60-O75 Complications of labour and delivery
0.700 0.300 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.700 0.300 0.000
N26 Unspecified contracted kidney
0.699 0.301 0.000
O29 Complications of anaesthesia during pregnancy
0.699 0.301 0.000
O28 Abnormal findings on antenatal screening of mother
0.699 0.301 0.000
O22 Venous complications in pregnancy
0.699 0.301 0.000
O21 Excessive vomiting in pregnancy
0.699 0.301 0.000
O25 Malnutrition in pregnancy
0.699 0.301 0.000
O36.8 Maternal care for other specified foetal problems
0.698 0.302 0.000
E13 Other specified diabetes mellitus
0.698 0.302 0.000
E12 Malnutrition-related diabetes mellitus
0.698 0.302 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.697 0.303 0.000
Y10-Y34 Event of undetermined intent
0.697 0.303 0.000
Y00-Y09 Assault
0.697 0.303 0.000
X85-X99 Assault
0.697 0.303 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.697 0.303 0.000
X50-X57 Overexertion, travel and privation
0.697 0.303 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.697 0.303 0.000
X30-X39 Exposure to forces of nature
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
X00-X09 Exposure to smoke, fire and flames
0.697 0.303 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.697 0.303 0.000
W75-W84 Other accidental threats to breathing
0.697 0.303 0.000
W65-W74 Accidental drowning and submersion
0.697 0.303 0.000
V98-V99 Other and unspecified transport accidents
0.697 0.303 0.000
V95-V97 Air and space transport accidents
0.697 0.303 0.000
V90-V94 Water transport accidents
0.697 0.303 0.000
V70-V79 Bus occupant injured in transport accident
0.697 0.303 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.697 0.303 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.697 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.303 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.697 0.303 0.000
V01-V09 Pedestrian injured in transport accident
0.697 0.303 0.000
E20 Hypoparathyroidism
0.696 0.304 0.000
I62 Other nontraumatic intracranial haemorrhage
0.695 0.304 0.000
N73 Other female pelvic inflammatory diseases
0.695 0.305 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.695 0.305 0.000
A48 Other bacterial diseases, not elsewhere classified
0.694 0.306 0.000
A44 Bartonellosis
0.694 0.306 0.000
A43 Nocardiosis
0.694 0.306 0.000
A42 Actinomycosis
0.694 0.306 0.000
A40 Streptococcal septicaemia
0.694 0.306 0.000
A39 Meningococcal infection
0.694 0.306 0.000
A37 Whooping cough
0.694 0.306 0.000
A36 Diphtheria
0.694 0.306 0.000
A32 Listeriosis
0.694 0.306 0.000
A31 Infection due to other mycobacteria
0.694 0.306 0.000
A30 Leprosy [Hansen's disease]
0.694 0.306 0.000
A38 Scarlet fever
0.694 0.306 0.000
A35 Other tetanus
0.694 0.306 0.000
A34 Obstetrical tetanus
0.694 0.306 0.000
A33 Tetanus neonatorum
0.694 0.306 0.000
H18.4 Corneal degeneration
0.694 0.306 0.000
S80 Superficial injury of lower leg
0.693 0.307 0.000
O36.6 Maternal care for excessive foetal growth
0.693 0.307 0.000
E87.6 Hypokalaemia
0.692 0.308 0.000
H43.8 Other disorders of vitreous body
0.692 0.308 0.000
I51.9 Heart disease, unspecified
0.692 0.308 0.000
T66-T78 Other and unspecified effects of external causes
0.691 0.309 0.000
S05 Injury of eye and orbit
0.691 0.309 0.000
E87.5 Hyperkalaemia
0.691 0.309 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.691 0.309 0.000
B37.3 Candidiasis of vulva and vagina
0.691 0.309 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.690 0.310 0.000
E87.4 Mixed disorder of acid-base balance
0.690 0.310 0.000
E87.3 Alkalosis
0.690 0.310 0.000
K70-K77 Diseases of liver
0.690 0.310 0.000
H74.4 Polyp of middle ear
0.690 0.310 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.689 0.311 0.000
A46 Erysipelas
0.689 0.311 0.000
H73.8 Other specified disorders of tympanic membrane
0.689 0.311 0.000
G62.9 Polyneuropathy, unspecified
0.689 0.311 0.000
Z93.6 Other artificial openings of urinary tract status
0.689 0.311 0.000
A41.8 Other specified septicaemia
0.688 0.312 0.000
N03 Chronic nephritic syndrome
0.688 0.312 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.687 0.313 0.000
S00 Superficial injury of head
0.687 0.313 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.686 0.313 0.000
I78.1 Naevus, nonneoplastic
0.686 0.313 0.000
W20-W49 Exposure to inanimate mechanical forces
0.686 0.314 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.686 0.314 0.000
J17 Pneumonia in diseases classified elsewhere
0.686 0.314 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.686 0.314 0.000
J12 Viral pneumonia, not elsewhere classified
0.686 0.314 0.000
J11 Influenza, virus not identified
0.686 0.314 0.000
J09 Influenza due to certain identified influenza virus
0.686 0.314 0.000
S90-S99 Injuries to the ankle and foot
0.686 0.314 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.686 0.314 0.000
M10 Gout
0.686 0.314 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.685 0.315 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.685 0.315 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.685 0.315 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.684 0.316 0.000
O32.1 Maternal care for breech presentation
0.684 0.316 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.684 0.316 0.000
D80-D89 Certain disorders involving the immune mechanism
0.684 0.316 0.000
E11.4 With neurological complications
0.684 0.316 0.000
E23 Hypofunction and other disorders of pituitary gland
0.682 0.318 0.000
O48 Prolonged pregnancy
0.681 0.319 0.000
Z95.3 Presence of xenogenic heart valve
0.680 0.320 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.680 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.320 0.000
H52 Disorders of refraction and accommodation
0.680 0.320 0.000
E10.8 With unspecified complications
0.679 0.320 0.000
E10.7 With multiple complications
0.679 0.320 0.000
E10.6 With other specified complications
0.679 0.320 0.000
E10.0 With coma
0.679 0.320 0.000
S50-S59 Injuries to the elbow and forearm
0.679 0.321 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.678 0.321 0.000
O26.8 Other specified pregnancy-related conditions
0.679 0.321 0.000
Z83 Family history of other specific disorders
0.678 0.322 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.678 0.322 0.000
S20-S29 Injuries to the thorax
0.677 0.322 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.677 0.323 0.000
O47.0 False labour before 37 completed weeks of gestation
0.677 0.323 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.675 0.325 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.675 0.325 0.000
I67.5 Moyamoya disease
0.675 0.325 0.000
I67.4 Hypertensive encephalopathy
0.675 0.325 0.000
I67.3 Progressive vascular leukoencephalopathy
0.675 0.325 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.675 0.325 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.675 0.325 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.675 0.325 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.675 0.325 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.674 0.325 0.000
B25-B34 Other viral diseases
0.674 0.326 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.674 0.326 0.000
E10.9 Without complications
0.673 0.327 0.000
T87.6 Other and unspecified complications of amputation stump
0.673 0.327 0.000
K90-K93 Other diseases of the digestive system
0.673 0.327 0.000
I63 Cerebral infarction
0.673 0.327 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.672 0.328 0.000
I50 Heart failure
0.672 0.328 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.672 0.328 0.000
Z98.8 Other specified postsurgical states
0.671 0.329 0.000
N70 Salpingitis and oophoritis
0.671 0.329 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.671 0.329 0.000
S48 Traumatic amputation of shoulder and upper arm
0.671 0.329 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.671 0.329 0.000
S44 Injury of nerves at shoulder and upper arm level
0.671 0.329 0.000
S41 Open wound of shoulder and upper arm
0.671 0.329 0.000
S47 Crushing injury of shoulder and upper arm
0.671 0.329 0.000
H34.8 Other retinal vascular occlusions
0.669 0.331 0.000
H43.9 Disorder of vitreous body, unspecified
0.669 0.331 0.000
H43.2 Crystalline deposits in vitreous body
0.669 0.331 0.000
H43.0 Vitreous prolapse
0.669 0.331 0.000
I70 Atherosclerosis
0.669 0.331 0.000
S70-S79 Injuries to the hip and thigh
0.669 0.331 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.668 0.331 0.000
N27 Small kidney of unknown cause
0.668 0.331 0.000
N25 Disorders resulting from impaired renal tubular function
0.668 0.331 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.668 0.332 0.000
Z93.9 Artificial opening status, unspecified
0.668 0.332 0.000
Z93.8 Other artificial opening status
0.668 0.332 0.000
N13.8 Other obstructive and reflux uropathy
0.668 0.332 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.668 0.332 0.000
E65-E68 Obesity and other hyperalimentation
0.667 0.333 0.000
S42.4 Fracture of lower end of humerus
0.667 0.333 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.667 0.333 0.000
A49.1 Streptococcal infection, unspecified
0.667 0.333 0.000
D60-D64 Aplastic and other anaemias
0.666 0.333 0.000
J32 Chronic sinusitis
0.666 0.334 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.666 0.334 0.000
H31 Other disorders of choroid
0.666 0.334 0.000
H30 Chorioretinal inflammation
0.666 0.334 0.000
A41.4 Septicaemia due to anaerobes
0.665 0.335 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.665 0.335 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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