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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34182778
log Bayes Factor = 229.887
Chromosome 6   position 31,084,942  (GRCh37) Explore rs34182778 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
K75 Other inflammatory liver diseases
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
L40 Psoriasis
0.000 0.003 0.997
K90-K93 Other diseases of the digestive system
0.997 0.003 0.000
I73 Other peripheral vascular diseases
0.997 0.003 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.997 0.003 0.000
E20-E35 Disorders of other endocrine glands
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.996 0.004 0.000
K73 Chronic hepatitis, not elsewhere classified
0.995 0.005 0.000
E10.1 With ketoacidosis
0.995 0.005 0.000
K75.4 Autoimmune hepatitis
0.993 0.007 0.000
E14.3 With ophthalmic complications
0.992 0.008 0.000
I73.9 Peripheral vascular disease, unspecified
0.992 0.008 0.000
C18 Malignant neoplasm of colon
0.991 0.009 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
E27 Other disorders of adrenal gland
0.990 0.010 0.000
E27.1 Primary adrenocortical insufficiency
0.989 0.011 0.000
I73.0 Raynaud's syndrome
0.988 0.012 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.988 0.012 0.000
C18.7 Sigmoid colon
0.983 0.017 0.000
L40.5 Arthropathic psoriasis
0.000 0.018 0.982
C83 Diffuse non-Hodgkin's lymphoma
0.980 0.020 0.000
D80-D89 Certain disorders involving the immune mechanism
0.978 0.022 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.974 0.026 0.000
C16 Malignant neoplasm of stomach
0.974 0.026 0.000
K75.8 Other specified inflammatory liver diseases
0.974 0.026 0.000
C83.3 Large cell (diffuse)
0.973 0.027 0.000
I74 Arterial embolism and thrombosis
0.973 0.027 0.000
K73.9 Chronic hepatitis, unspecified
0.973 0.027 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.970 0.030 0.000
I77 Other disorders of arteries and arterioles
0.968 0.032 0.000
L40.0 Psoriasis vulgaris
0.000 0.037 0.963
C71 Malignant neoplasm of brain
0.956 0.044 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.951 0.049 0.000
C85.1 B-cell lymphoma, unspecified
0.947 0.053 0.000
I77.1 Stricture of artery
0.947 0.053 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.938 0.062 0.000
K90.9 Intestinal malabsorption, unspecified
0.937 0.063 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.929 0.071 0.000
I05-I09 Chronic rheumatic heart diseases
0.928 0.072 0.000
C71.9 Brain, unspecified
0.926 0.074 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.917 0.083 0.000
D80 Immunodeficiency with predominantly antibody defects
0.916 0.084 0.000
C18.1 Appendix
0.910 0.090 0.000
C71.0 Cerebrum, except lobes and ventricles
0.907 0.093 0.000
I08 Multiple valve diseases
0.907 0.093 0.000
K70 Alcoholic liver disease
0.907 0.093 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.903 0.097 0.000
C92 Myeloid leukaemia
0.901 0.099 0.000
K72 Hepatic failure, not elsewhere classified
0.899 0.101 0.000
C23 Malignant neoplasm of gallbladder
0.899 0.101 0.000
D61 Other aplastic anaemias
0.896 0.104 0.000
D86 Sarcoidosis
0.896 0.104 0.000
E10.4 With neurological complications
0.896 0.104 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.895 0.105 0.000
E10.2 With renal complications
0.890 0.110 0.000
C91 Lymphoid leukaemia
0.885 0.115 0.000
C18.5 Splenic flexure
0.877 0.123 0.000
E07 Other disorders of thyroid
0.875 0.125 0.000
I74.8 Embolism and thrombosis of other arteries
0.874 0.126 0.000
I74.5 Embolism and thrombosis of iliac artery
0.873 0.127 0.000
D86.9 Sarcoidosis, unspecified
0.869 0.131 0.000
E28 Ovarian dysfunction
0.865 0.135 0.000
C15 Malignant neoplasm of oesophagus
0.860 0.140 0.000
E16 Other disorders of pancreatic internal secretion
0.858 0.142 0.000
C07 Malignant neoplasm of parotid gland
0.855 0.145 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.855 0.145 0.000
C04 Malignant neoplasm of floor of mouth
0.854 0.146 0.000
C16.0 Cardia
0.853 0.147 0.000
E24 Cushing's syndrome
0.852 0.148 0.000
C16.9 Stomach, unspecified
0.852 0.148 0.000
E40-E46 Malnutrition
0.850 0.149 0.000
E14.1 With ketoacidosis
0.844 0.156 0.000
D61.9 Aplastic anaemia, unspecified
0.843 0.157 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.841 0.159 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.838 0.162 0.000
E06 Thyroiditis
0.838 0.162 0.000
E03.8 Other specified hypothyroidism
0.834 0.166 0.000
C91.1 Chronic lymphocytic leukaemia
0.833 0.167 0.000
E23 Hypofunction and other disorders of pituitary gland
0.830 0.170 0.000
D62 Acute posthaemorrhagic anaemia
0.822 0.178 0.000
K74 Fibrosis and cirrhosis of liver
0.821 0.179 0.000
E10.8 With unspecified complications
0.819 0.181 0.000
C21 Malignant neoplasm of anus and anal canal
0.816 0.184 0.000
C15.4 Middle third of oesophagus
0.812 0.188 0.000
L40.8 Other psoriasis
0.000 0.189 0.811
D80.1 Nonfamilial hypogammaglobulinaemia
0.810 0.190 0.000
I08.8 Other multiple valve diseases
0.810 0.190 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.809 0.191 0.000
C92.1 Chronic myeloid leukaemia
0.808 0.192 0.000
C84.5 Other and unspecified T-cell lymphomas
0.807 0.193 0.000
C16.8 Overlapping lesion of stomach
0.806 0.194 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.806 0.194 0.000
E16.2 Hypoglycaemia, unspecified
0.804 0.196 0.000
K72.0 Acute and subacute hepatic failure
0.804 0.196 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.802 0.198 0.000
E23.2 Diabetes insipidus
0.800 0.200 0.000
I77.6 Arteritis, unspecified
0.799 0.201 0.000
C10 Malignant neoplasm of oropharynx
0.798 0.202 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.795 0.205 0.000
E10.0 With coma
0.795 0.205 0.000
C88 Malignant immunoproliferative diseases
0.794 0.206 0.000
E31 Polyglandular dysfunction
0.789 0.211 0.000
D55-D59 Haemolytic anaemias
0.786 0.213 0.000
C95 Leukaemia of unspecified cell type
0.783 0.217 0.000
K70.0 Alcoholic fatty liver
0.780 0.220 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.780 0.220 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.779 0.221 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.779 0.221 0.000
D83 Common variable immunodeficiency
0.778 0.222 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.778 0.222 0.000
E14.6 With other specified complications
0.776 0.224 0.000
M35.0 Sicca syndrome [Sjogren]
0.776 0.224 0.000
E10.6 With other specified complications
0.774 0.226 0.000
E14.8 With unspecified complications
0.774 0.226 0.000
C83.0 Small cell (diffuse)
0.773 0.227 0.000
C71.7 Brain stem
0.772 0.228 0.000
C16.3 Pyloric antrum
0.772 0.228 0.000
E27.2 Addisonian crisis
0.772 0.228 0.000
I77.2 Rupture of artery
0.771 0.229 0.000
K90.8 Other intestinal malabsorption
0.768 0.232 0.000
C05 Malignant neoplasm of palate
0.767 0.233 0.000
K70.9 Alcoholic liver disease, unspecified
0.767 0.233 0.000
K71 Toxic liver disease
0.764 0.236 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.761 0.239 0.000
E20 Hypoparathyroidism
0.760 0.240 0.000
C70 Malignant neoplasm of meninges
0.759 0.241 0.000
C16.6 Greater curvature of stomach, unspecified
0.756 0.243 0.000
E14.2 Withrenal complications
0.755 0.245 0.000
K70.4 Alcoholic hepatic failure
0.750 0.250 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.750 0.250 0.000
E06.3 Autoimmune thyroiditis
0.749 0.251 0.000
E24.2 Drug-induced Cushing's syndrome
0.744 0.256 0.000
E46 Unspecified protein-energy malnutrition
0.743 0.257 0.000
E07.8 Other specified disorders of thyroid
0.739 0.261 0.000
D84 Other immunodeficiencies
0.737 0.263 0.000
Chapter VII Diseases of the eye and adnexa
0.736 0.264 0.000
H30-H36 Disorders of choroid and retina
0.733 0.267 0.000
C16.1 Fundus of stomach
0.733 0.267 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.732 0.268 0.000
C03 Malignant neoplasm of gum
0.731 0.269 0.000
H36 Retinal disorders in diseases classified elsewhere
0.731 0.269 0.000
L40.1 Generalised pustular psoriasis
0.000 0.269 0.731
H36.0 Diabetic retinopathy
0.731 0.269 0.000
C16.2 Body of stomach
0.729 0.271 0.000
C04.0 Anterior floor of mouth
0.729 0.271 0.000
K74.3 Primary biliary cirrhosis
0.726 0.274 0.000
C86 Other specified types of T/NK-cell lymphoma
0.725 0.275 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.725 0.275 0.000
C18.6 Descending colon
0.724 0.276 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.722 0.278 0.000
M06.9 Rheumatoid arthritis, unspecified
0.722 0.278 0.000
C92.0 Acute myeloid leukaemia
0.722 0.278 0.000
E14.5 With peripheral circulatory complications
0.721 0.279 0.000
E10.5 With peripheral circulatory complications
0.721 0.279 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.716 0.284 0.000
K75.1 Phlebitis of portal vein
0.716 0.284 0.000
L40.4 Guttate psoriasis
0.000 0.285 0.715
L40.3 Pustulosis palmaris et plantaris
0.000 0.285 0.715
L40.2 Acrodermatitis continua
0.000 0.285 0.715
K93 Disorders of other digestive organs in diseases classified elsewhere
0.715 0.285 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.715 0.285 0.000
E28.2 Polycystic ovarian syndrome
0.715 0.285 0.000
K75.0 Abscess of liver
0.715 0.285 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.714 0.286 0.000
E32 Diseases of thymus
0.714 0.286 0.000
E30 Disorders of puberty, not elsewhere classified
0.714 0.286 0.000
E25 Adrenogenital disorders
0.714 0.286 0.000
C84.0 Mycosis fungoides
0.714 0.286 0.000
E14.7 With multiple complications
0.714 0.286 0.000
E14.0 With coma
0.714 0.286 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.714 0.286 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.713 0.287 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.713 0.287 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.713 0.287 0.000
E28.3 Primary ovarian failure
0.712 0.288 0.000
E07.9 Disorder of thyroid, unspecified
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.710 0.290 0.000
E27.5 Adrenomedullary hyperfunction
0.710 0.290 0.000
E27.0 Other adrenocortical overactivity
0.710 0.290 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.709 0.291 0.000
C85.0 Lymphosarcoma
0.708 0.292 0.000
C18.0 Caecum
0.708 0.292 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.707 0.293 0.000
C71.4 Occipital lobe
0.706 0.294 0.000
C00 Malignant neoplasm of lip
0.706 0.294 0.000
C83.6 Undifferentiated (diffuse)
0.703 0.297 0.000
C83.5 Lymphoblastic (diffuse)
0.703 0.297 0.000
C83.4 Immunoblastic (diffuse)
0.703 0.297 0.000
C83.2 Mixed small and large cell (diffuse)
0.703 0.297 0.000
C81 Hodgkin's disease
0.702 0.298 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.702 0.298 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.701 0.298 0.000
D81 Combined immunodeficiencies
0.701 0.299 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.701 0.299 0.000
K72.9 Hepatic failure, unspecified
0.700 0.300 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.698 0.301 0.000
D69 Purpura and other haemorrhagic conditions
0.697 0.303 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.696 0.303 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.696 0.304 0.000
C92.9 Myeloid leukaemia, unspecified
0.696 0.304 0.000
C16.4 Pylorus
0.696 0.304 0.000
C04.9 Floor of mouth, unspecified
0.695 0.305 0.000
I77.5 Necrosis of artery
0.694 0.306 0.000
I77.4 Coeliac artery compression syndrome
0.694 0.306 0.000
I77.3 Arterial fibromuscular dysplasia
0.694 0.306 0.000
C17 Malignant neoplasm of small intestine
0.689 0.311 0.000
I77.0 Arteriovenous fistula, acquired
0.688 0.312 0.000
C91.9 Lymphoid leukaemia, unspecified
0.688 0.312 0.000
C71.6 Cerebellum
0.686 0.314 0.000
C71.5 Cerebral ventricle
0.686 0.314 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.685 0.315 0.000
D64.8 Other specified anaemias
0.682 0.318 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.681 0.319 0.000
D00-D09 In situ neoplasms
0.681 0.319 0.000
I06 Rheumatic aortic valve diseases
0.681 0.319 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.680 0.320 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.679 0.321 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.675 0.325 0.000
C10.9 Oropharynx, unspecified
0.674 0.325 0.000
I99 Other and unspecified disorders of circulatory system
0.674 0.326 0.000
E03.1 Congenital hypothyroidism without goitre
0.673 0.327 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.673 0.327 0.000
C06.0 Cheek mucosa
0.673 0.327 0.000
K70.1 Alcoholic hepatitis
0.673 0.327 0.000
J45.9 Asthma, unspecified
0.672 0.328 0.000
C13 Malignant neoplasm of hypopharynx
0.671 0.329 0.000
E27.9 Disorder of adrenal gland, unspecified
0.669 0.331 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.669 0.331 0.000
H33 Retinal detachments and breaks
0.668 0.332 0.000
I71 Aortic aneurysm and dissection
0.667 0.333 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.667 0.333 0.000
E13 Other specified diabetes mellitus
0.666 0.334 0.000
C91.5 Adult T-cell leukaemia
0.666 0.334 0.000
D82 Immunodeficiency associated with other major defects
0.664 0.335 0.000
C71.1 Frontal lobe
0.663 0.337 0.000
I00-I02 Acute rheumatic fever
0.661 0.339 0.000
C16.5 Lesser curvature of stomach, unspecified
0.660 0.340 0.000
C93 Monocytic leukaemia
0.658 0.342 0.000
E15 Nondiabetic hypoglycaemic coma
0.658 0.342 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.657 0.343 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.657 0.343 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.657 0.343 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.657 0.343 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.657 0.343 0.000
I08.9 Multiple valve disease, unspecified
0.656 0.344 0.000
D59 Acquired haemolytic anaemia
0.655 0.345 0.000
C21.0 Anus, unspecified
0.655 0.345 0.000
H06.2 Dysthyroid exophthalmos
0.654 0.346 0.000
E24.0 Pituitary-dependent Cushing's disease
0.653 0.347 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.652 0.348 0.000
C83.1 Small cleaved cell (diffuse)
0.650 0.350 0.000
K72.1 Chronic hepatic failure
0.649 0.350 0.000
C02.1 Border of tongue
0.649 0.351 0.000
C71.8 Overlapping lesion of brain
0.648 0.352 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.648 0.352 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.648 0.352 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.648 0.352 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.648 0.352 0.000
C84.3 Lymphoepithelioid lymphoma
0.648 0.352 0.000
C84.2 T-zone lymphoma
0.648 0.352 0.000
C84.1 Sezary's diease
0.648 0.352 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.647 0.353 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.647 0.353 0.000
D86.3 Sarcoidosis of skin
0.647 0.353 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.646 0.353 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.646 0.354 0.000
C92.7 Other myeloid leukaemia
0.646 0.354 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.646 0.354 0.000
C92.5 Acute myelomonocytic leukaemia
0.646 0.354 0.000
C92.3 Myeloid sarcoma
0.646 0.354 0.000
C92.2 Subacute myeloid leukaemia
0.646 0.354 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.644 0.356 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.643 0.356 0.000
D61.8 Other specified aplastic anaemias
0.643 0.357 0.000
D61.3 Idiopathic aplastic anaemia
0.643 0.357 0.000
D61.2 Aplastic anaemia due to other external agents
0.643 0.357 0.000
H05 Disorders of orbit
0.642 0.358 0.000
E31.0 Autoimmune polyglandular failure
0.641 0.359 0.000
M06 Other rheumatoid arthritis
0.640 0.360 0.000
C02.9 Tongue, unspecified
0.640 0.360 0.000
C15.9 Oesophagus, unspecified
0.640 0.360 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.638 0.362 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.636 0.364 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.636 0.364 0.000
H33.1 Retinoschisis and retinal cysts
0.636 0.364 0.000
C83.7 Burkitt's tumour
0.635 0.364 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.635 0.364 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.635 0.365 0.000
D83.9 Common variable immunodeficiency, unspecified
0.635 0.365 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.635 0.365 0.000
C91.7 Other lymphoid leukaemia
0.635 0.365 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.635 0.365 0.000
C91.3 Prolymphocytic leukaemia
0.635 0.365 0.000
C91.2 Subacute lymphocytic leukaemia
0.635 0.365 0.000
C11 Malignant neoplasm of nasopharynx
0.633 0.367 0.000
E06.5 Other chronic thyroiditis
0.632 0.367 0.000
D69.6 Thrombocytopenia, unspecified
0.631 0.369 0.000
I09 Other rheumatic heart diseases
0.631 0.369 0.000
C95.9 Leukaemia, unspecified
0.628 0.372 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.628 0.372 0.000
C18.3 Hepatic flexure
0.627 0.372 0.000
H04 Disorders of lachrymal system
0.628 0.372 0.000
E07.1 Dyshormogenetic goitre
0.627 0.373 0.000
E07.0 Hypersecretion of calcitonin
0.627 0.373 0.000
C84.4 Peripheral T-cell lymphoma
0.627 0.373 0.000
H33.3 Retinal breaks without detachment
0.627 0.373 0.000
C01 Malignant neoplasm of base of tongue
0.624 0.376 0.000
H55-H59 Other disorders of eye and adnexa
0.623 0.377 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.621 0.378 0.000
K74.6 Other and unspecified cirrhosis of liver
0.621 0.379 0.000
C69 Malignant neoplasm of eye and adnexa
0.620 0.379 0.000
E28.9 Ovarian dysfunction, unspecified
0.620 0.380 0.000
E28.8 Other ovarian dysfunction
0.620 0.380 0.000
E28.1 Androgen excess
0.620 0.380 0.000
E28.0 Oestrogen excess
0.620 0.380 0.000
C05.1 Soft palate
0.618 0.382 0.000
C15.8 Overlapping lesion of oesophagus
0.617 0.383 0.000
C15.2 Abdominal part of oesophagus
0.617 0.383 0.000
C15.1 Thoracic part of oesophagus
0.617 0.383 0.000
C15.0 Cervical part of oesophagus
0.617 0.383 0.000
M05-M14 Inflammatory polyarthropathies
0.617 0.383 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.616 0.384 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.615 0.384 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.615 0.385 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.615 0.385 0.000
E16.4 Abnormal secretion of gastrin
0.615 0.385 0.000
E16.3 Increased secretion of glucagon
0.615 0.385 0.000
C15.3 Upper third of oesophagus
0.615 0.385 0.000
M35 Other systemic involvement of connective tissue
0.615 0.385 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.614 0.386 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.614 0.386 0.000
C04.8 Overlapping lesion of floor of mouth
0.613 0.387 0.000
C04.1 Lateral floor of mouth
0.613 0.387 0.000
E24.8 Other Cushing's syndrome
0.611 0.389 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.611 0.389 0.000
E24.3 Ectopic ACTH syndrome
0.611 0.389 0.000
E24.1 Nelson's syndrome
0.611 0.389 0.000
I07 Rheumatic tricuspid valve diseases
0.610 0.390 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.610 0.390 0.000
E45 Retarded development following protein-energy malnutrition
0.610 0.390 0.000
E43 Unspecified severe protein-energy malnutrition
0.610 0.390 0.000
E42 Marasmic kwashiorkor
0.610 0.390 0.000
E41 Nutritional marasmus
0.610 0.390 0.000
E40 Kwashiorkor
0.610 0.390 0.000
E26 Hyperaldosteronism
0.607 0.392 0.000
C09 Malignant neoplasm of tonsil
0.606 0.393 0.000
C60-C63 Malignant neoplasms of male genital organs
0.606 0.394 0.000
E34 Other endocrine disorders
0.604 0.396 0.000
C70.0 Cerebral meninges
0.604 0.396 0.000
C18.9 Colon, unspecified
0.604 0.396 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.602 0.397 0.000
Q50-Q56 Congenital malformations of genital organs
0.602 0.398 0.000
I79.1 Aortitis in diseases classified elsewhere
0.601 0.399 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.601 0.399 0.000
E06.4 Drug-induced thyroiditis
0.601 0.399 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.601 0.399 0.000
E06.1 Subacute thyroiditis
0.601 0.399 0.000
E06.0 Acute thyroiditis
0.601 0.399 0.000
C17.9 Small intestine, unspecified
0.601 0.399 0.000
D86.0 Sarcoidosis of lung
0.600 0.399 0.000
C06.2 Retromolar area
0.600 0.400 0.000
E22 Hyperfunction of pituitary gland
0.600 0.400 0.000
D61.0 Constitutional aplastic anaemia
0.600 0.400 0.000
C18.8 Overlapping lesion of colon
0.599 0.401 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.597 0.403 0.000
C18.4 Transverse colon
0.597 0.403 0.000
H30 Chorioretinal inflammation
0.596 0.404 0.000
D61.1 Drug-induced aplastic anaemia
0.596 0.404 0.000
K71.0 Toxic liver disease with cholestasis
0.596 0.404 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.595 0.405 0.000
E23.1 Drug-induced hypopituitarism
0.595 0.405 0.000
D69.4 Other primary thrombocytopenia
0.592 0.408 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.590 0.409 0.000
E20.9 Hypoparathyroidism, unspecified
0.591 0.409 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.590 0.410 0.000
K74.4 Secondary biliary cirrhosis
0.589 0.411 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.589 0.411 0.000
K74.1 Hepatic sclerosis
0.589 0.411 0.000
C25 Malignant neoplasm of pancreas
0.587 0.413 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.585 0.415 0.000
C21.2 Cloacogenic zone
0.585 0.415 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.585 0.415 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.584 0.416 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.584 0.416 0.000
C06.9 Mouth, unspecified
0.583 0.416 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.584 0.416 0.000
H05.0 Acute inflammation of orbit
0.582 0.418 0.000
D86.1 Sarcoidosis of lymph nodes
0.581 0.419 0.000
C71.3 Parietal lobe
0.581 0.419 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.578 0.422 0.000
C06.1 Vestibule of mouth
0.578 0.422 0.000
C81.1 Nodular sclerosis
0.577 0.423 0.000
E24.9 Cushing's syndrome, unspecified
0.575 0.425 0.000
Q00-Q07 Congenital malformations of the nervous system
0.574 0.426 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.573 0.427 0.000
H04.2 Epiphora
0.573 0.427 0.000
C10.8 Overlapping lesion of oropharynx
0.572 0.428 0.000
C10.4 Branchial cleft
0.572 0.428 0.000
C10.3 Posterior wall of oropharynx
0.572 0.428 0.000
C10.2 Lateral wall of oropharynx
0.572 0.428 0.000
C10.1 Anterior surface of epiglottis
0.572 0.428 0.000
C10.0 Vallecula
0.572 0.428 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.572 0.428 0.000
E05.8 Other thyrotoxicosis
0.572 0.428 0.000
D04 Carcinoma in situ of skin
0.572 0.428 0.000
C02.8 Overlapping lesion of tongue
0.570 0.430 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.570 0.430 0.000
C02.0 Dorsal surface of tongue
0.570 0.430 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.569 0.431 0.000
C88.7 Other malignant immunoproliferative diseases
0.569 0.431 0.000
C88.3 Immunoproliferative small intestinal disease
0.569 0.431 0.000
C88.2 Gamma heavy chain disease
0.569 0.431 0.000
C88.1 Alpha heavy chain disease
0.569 0.431 0.000
C12 Malignant neoplasm of pyriform sinus
0.569 0.431 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.569 0.431 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.567 0.432 0.000
D59.1 Other autoimmune haemolytic anaemias
0.568 0.432 0.000
D58 Other hereditary haemolytic anaemias
0.568 0.432 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.566 0.434 0.000
E31.9 Polyglandular dysfunction, unspecified
0.566 0.434 0.000
E31.8 Other polyglandular dysfunction
0.566 0.434 0.000
E31.1 Polyglandular hyperfunction
0.566 0.434 0.000
K74.0 Hepatic fibrosis
0.564 0.436 0.000
D57 Sickle-cell disorders
0.564 0.436 0.000
D55 Anaemia due to enzyme disorders
0.564 0.436 0.000
M20-M25 Other joint disorders
0.562 0.438 0.000
C95.7 Other leukaemia of unspecified cell type
0.561 0.438 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.561 0.438 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.561 0.438 0.000
C95.0 Acute leukaemia of unspecified cell type
0.561 0.438 0.000
C05.0 Hard palate
0.561 0.439 0.000
K70.3 Alcoholic cirrhosis of liver
0.561 0.439 0.000
E23.6 Other disorders of pituitary gland
0.560 0.440 0.000
C03.1 Lower gum
0.560 0.440 0.000
D07.1 Vulva
0.560 0.440 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.472 0.440 0.088
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.559 0.441 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.559 0.441 0.000
I98.0 Cardiovascular syphilis
0.559 0.441 0.000
E29 Testicular dysfunction
0.559 0.441 0.000
D60.8 Other acquired pure red cell aplasias
0.559 0.441 0.000
D60.1 Transient acquired pure red cell aplasia
0.559 0.441 0.000
D60.0 Chronic acquired pure red cell aplasia
0.559 0.441 0.000
D69.0 Allergic purpura
0.558 0.442 0.000
D83.8 Other common variable immunodeficiencies
0.558 0.442 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.558 0.442 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.558 0.442 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.558 0.442 0.000
E14.9 Without complications
0.558 0.442 0.000
D84.9 Immunodeficiency, unspecified
0.557 0.443 0.000
L40-L45 Papulosquamous disorders
0.165 0.445 0.390

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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