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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17857515
log Bayes Factor = 18.2473
Chromosome 9   position 32,542,278  (GRCh37) Explore rs17857515 on Ensembl!
Variant rs17857515 is part of Cluster X0055

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Z86 Personal history of certain other diseases
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
Z86.0 Personal history of other neoplasms
0.989 0.011 0.000
M70-M79 Other soft tissue disorders
0.989 0.011 0.000
S80-S89 Injuries to the knee and lower leg
0.984 0.016 0.000
Z85 Personal history of malignant neoplasm
0.983 0.017 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.977 0.023 0.000
Chapter XI Diseases of the digestive system
0.977 0.023 0.000
M50-M54 Other dorsopathies
0.977 0.023 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.976 0.024 0.000
C15-C26 Malignant neoplasms of digestive organs
0.971 0.029 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.971 0.029 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.969 0.031 0.000
Z86.7 Personal history of diseases of the circulatory system
0.968 0.032 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.967 0.033 0.000
G40-G47 Episodic and paroxysmal disorders
0.963 0.037 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.962 0.038 0.000
I45 Other conduction disorders
0.960 0.040 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.960 0.040 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.957 0.043 0.000
C64-C68 Malignant neoplasms of urinary tract
0.955 0.045 0.000
Chapter V Mental and behavioural disorders
0.953 0.047 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.952 0.048 0.000
H43-H45 Disorders of vitreous body and globe
0.951 0.049 0.000
K65-K67 Diseases of peritoneum
0.943 0.057 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.943 0.057 0.000
M79.8 Other specified soft tissue disorders
0.941 0.059 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.941 0.059 0.000
C15 Malignant neoplasm of oesophagus
0.933 0.067 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.933 0.067 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.930 0.070 0.000
S82 Fracture of lower leg, including ankle
0.929 0.071 0.000
I50 Heart failure
0.928 0.072 0.000
C67 Malignant neoplasm of bladder
0.927 0.073 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.926 0.074 0.000
H02 Other disorders of eyelid
0.926 0.074 0.000
I51 Complications and ill-defined descriptions of heart disease
0.926 0.074 0.000
H43 Disorders of vitreous body
0.922 0.078 0.000
K66 Other disorders of peritoneum
0.917 0.083 0.000
Z96 Presence of other functional implants
0.917 0.083 0.000
C77.2 Intra-abdominal lymph nodes
0.915 0.085 0.000
I45.1 Other and unspecified right bundle-branch block
0.913 0.087 0.000
Chapter XX External causes of morbidity and mortality
0.910 0.090 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.906 0.094 0.000
S80 Superficial injury of lower leg
0.906 0.094 0.000
C67.9 Bladder, unspecified
0.904 0.096 0.000
K13 Other diseases of lip and oral mucosa
0.904 0.096 0.000
Z99.8 Dependence on other enabling machines and devices
0.901 0.099 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.901 0.099 0.000
Z60 Problems related to social environment
0.899 0.101 0.000
I05-I09 Chronic rheumatic heart diseases
0.896 0.104 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.896 0.104 0.000
E50-E64 Other nutritional deficiencies
0.894 0.106 0.000
G47 Sleep disorders
0.893 0.107 0.000
S82.8 Fractures of other parts of lower leg
0.893 0.107 0.000
S20-S29 Injuries to the thorax
0.892 0.108 0.000
M05-M14 Inflammatory polyarthropathies
0.891 0.109 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.890 0.110 0.000
K70-K77 Diseases of liver
0.889 0.111 0.000
I51.8 Other ill-defined heart diseases
0.888 0.112 0.000
K66.0 Peritoneal adhesions
0.887 0.113 0.000
M50 Cervical disk disorders
0.886 0.114 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.885 0.115 0.000
H40-H42 Glaucoma
0.884 0.116 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.878 0.122 0.000
E65-E68 Obesity and other hyperalimentation
0.876 0.124 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.873 0.127 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.872 0.128 0.000
D00-D09 In situ neoplasms
0.871 0.129 0.000
C77.3 Axillary and upper limb lymph nodes
0.871 0.129 0.000
M79.6 Pain in limb
0.868 0.132 0.000
M51 Other intervertebral disk disorders
0.868 0.132 0.000
G43 Migraine
0.868 0.132 0.000
G47.3 Sleep apnoea
0.866 0.134 0.000
S70-S79 Injuries to the hip and thigh
0.864 0.136 0.000
I85 Oesophageal varices
0.864 0.136 0.000
Z60.2 Living alone
0.861 0.139 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.861 0.139 0.000
H55-H59 Other disorders of eye and adnexa
0.859 0.141 0.000
C16 Malignant neoplasm of stomach
0.858 0.142 0.000
H53-H54 Visual disturbances and blindness
0.858 0.142 0.000
M13 Other arthritis
0.857 0.143 0.000
Z04 Examination and observation for other reasons
0.856 0.144 0.000
G40 Epilepsy
0.856 0.144 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.856 0.144 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.856 0.144 0.000
I42 Cardiomyopathy
0.855 0.145 0.000
S10-S19 Injuries to the neck
0.852 0.148 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.852 0.148 0.000
M54 Dorsalgia
0.851 0.149 0.000
C15.9 Oesophagus, unspecified
0.850 0.150 0.000
C60-C63 Malignant neoplasms of male genital organs
0.850 0.150 0.000
M50.3 Other cervical disk degeneration
0.850 0.150 0.000
C18 Malignant neoplasm of colon
0.847 0.153 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.846 0.154 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.845 0.155 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.844 0.156 0.000
S80.9 Superficial injury of lower leg, unspecified
0.843 0.157 0.000
H02.0 Entropion and trichiasis of eyelid
0.842 0.158 0.000
H43.8 Other disorders of vitreous body
0.841 0.159 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.839 0.161 0.000
H43.1 Vitreous haemorrhage
0.837 0.162 0.000
C51-C58 Malignant neoplasms of female genital organs
0.836 0.164 0.000
I50.0 Congestive heart failure
0.833 0.167 0.000
I86 Varicose veins of other sites
0.831 0.168 0.000
K80 Cholelithiasis
0.825 0.175 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.825 0.175 0.000
I81 Portal vein thrombosis
0.825 0.175 0.000
M72 Fibroblastic disorders
0.822 0.178 0.000
M45-M49 Spondylopathies
0.822 0.178 0.000
C15.4 Middle third of oesophagus
0.821 0.179 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.821 0.179 0.000
M13.9 Arthritis, unspecified
0.821 0.179 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.821 0.179 0.000
Z89 Acquired absence of limb
0.816 0.184 0.000
Z83 Family history of other specific disorders
0.816 0.184 0.000
S60-S69 Injuries to the wrist and hand
0.814 0.186 0.000
E10-E14 Diabetes mellitus
0.814 0.186 0.000
Z90.1 Acquired absence of breast(s)
0.812 0.188 0.000
M71 Other bursopathies
0.811 0.189 0.000
K11 Diseases of salivary glands
0.810 0.190 0.000
M79.66 Pain in limb (Lower leg)
0.810 0.190 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.809 0.191 0.000
H02.8 Other specified disorders of eyelid
0.808 0.192 0.000
Z99.3 Dependence on wheelchair
0.808 0.192 0.000
E53 Deficiency of other B group vitamins
0.807 0.193 0.000
Z96.6 Presence of orthopaedic joint implants
0.807 0.193 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.805 0.195 0.000
K02 Dental caries
0.804 0.196 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.804 0.196 0.000
E66 Obesity
0.803 0.197 0.000
T66-T78 Other and unspecified effects of external causes
0.803 0.197 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.803 0.197 0.000
H40 Glaucoma
0.802 0.198 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.802 0.198 0.000
G43.9 Migraine, unspecified
0.800 0.200 0.000
K74 Fibrosis and cirrhosis of liver
0.799 0.201 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.798 0.202 0.000
I85.9 Oesophageal varices without bleeding
0.794 0.206 0.000
E00-E07 Disorders of thyroid gland
0.793 0.207 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.792 0.208 0.000
G30-G32 Other degenerative diseases of the nervous system
0.790 0.210 0.000
I33 Acute and subacute endocarditis
0.788 0.212 0.000
S00-S09 Injuries to the head
0.787 0.213 0.000
I45.2 Bifascicular block
0.786 0.214 0.000
S29 Other and unspecified injuries of thorax
0.785 0.215 0.000
I74 Arterial embolism and thrombosis
0.785 0.215 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.785 0.215 0.000
Z85.6 Personal history of leukaemia
0.783 0.217 0.000
I50.9 Heart failure, unspecified
0.782 0.218 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.782 0.218 0.000
C80 Malignant neoplasm without specification of site
0.782 0.218 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.782 0.218 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.782 0.218 0.000
M54.1 Radiculopathy
0.781 0.219 0.000
Z57 Occupational exposure to risk-factors
0.781 0.219 0.000
C73 Malignant neoplasm of thyroid gland
0.780 0.220 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.220 0.000
H00 Hordeolum and chalazion
0.779 0.221 0.000
K13.0 Diseases of lips
0.778 0.222 0.000
L03 Cellulitis
0.778 0.222 0.000
C66 Malignant neoplasm of ureter
0.776 0.224 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.776 0.224 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.774 0.226 0.000
I05 Rheumatic mitral valve diseases
0.773 0.227 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.773 0.227 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.772 0.228 0.000
M91-M94 Chondropathies
0.771 0.228 0.000
S81 Open wound of lower leg
0.770 0.230 0.000
G50 Disorders of trigeminal nerve
0.769 0.231 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.769 0.231 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.769 0.231 0.000
I46 Cardiac arrest
0.768 0.232 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.767 0.233 0.000
Z96.8 Presence of other specified functional implants
0.767 0.233 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.766 0.234 0.000
F99-F99 Unspecified mental disorder
0.766 0.234 0.000
C61 Malignant neoplasm of prostate
0.766 0.234 0.000
E66.9 Obesity, unspecified
0.766 0.234 0.000
L03.0 Cellulitis of finger and toe
0.762 0.238 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.761 0.238 0.000
Z12 Special screening examination for neoplasms
0.760 0.240 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.760 0.240 0.000
I77 Other disorders of arteries and arterioles
0.760 0.240 0.000
S82.81 Fractures of other parts of lower leg (open)
0.760 0.240 0.000
I45.6 Preexcitation syndrome
0.759 0.241 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.759 0.241 0.000
G56 Mononeuropathies of upper limb
0.758 0.241 0.000
K12 Stomatitis and related lesions
0.758 0.242 0.000
I08 Multiple valve diseases
0.758 0.242 0.000
K10 Other diseases of jaws
0.756 0.244 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.756 0.244 0.000
M51.2 Other specified intervertebral disk displacement
0.755 0.245 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.754 0.246 0.000
I86.4 Gastric varices
0.753 0.247 0.000
K66.8 Other specified disorders of peritoneum
0.753 0.247 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.752 0.248 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.752 0.248 0.000
I49 Other cardiac arrhythmias
0.752 0.248 0.000
Z83.5 Family history of eye and ear disorders
0.752 0.248 0.000
S72 Fracture of femur
0.748 0.251 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.748 0.252 0.000
M40-M43 Deforming dorsopathies
0.748 0.252 0.000
Z97 Presence of other devices
0.746 0.253 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.746 0.253 0.000
C16.0 Cardia
0.746 0.254 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.745 0.255 0.000
Z96.1 Presence of intraocular lens
0.745 0.255 0.000
H02.4 Ptosis of eyelid
0.745 0.255 0.000
G90-G99 Other disorders of the nervous system
0.745 0.255 0.000
E53.8 Deficiency of other specified B group vitamins
0.744 0.256 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.743 0.257 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.742 0.258 0.000
G57 Mononeuropathies of lower limb
0.742 0.258 0.000
I87 Other disorders of veins
0.741 0.258 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.741 0.259 0.000
K00 Disorders of tooth development and eruption
0.741 0.259 0.000
S40-S49 Injuries to the shoulder and upper arm
0.739 0.261 0.000
Z94 Transplanted organ and tissue status
0.738 0.262 0.000
M79.5 Residual foreign body in soft tissue
0.738 0.262 0.000
K09 Cysts of oral region, not elsewhere classified
0.737 0.262 0.000
S50-S59 Injuries to the elbow and forearm
0.737 0.263 0.000
C18.2 Ascending colon
0.736 0.263 0.000
G70-G73 Diseases of myoneural junction and muscle
0.736 0.264 0.000
K86 Other diseases of pancreas
0.735 0.265 0.000
H54 Blindness and low vision
0.733 0.267 0.000
H02.1 Ectropion of eyelid
0.733 0.267 0.000
Z04.3 Examination and observation following other accident
0.732 0.268 0.000
C15.5 Lower third of oesophagus
0.732 0.268 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.731 0.269 0.000
K08 Other disorders of teeth and supporting structures
0.731 0.269 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.731 0.269 0.000
I30 Acute pericarditis
0.730 0.270 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.730 0.270 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.729 0.271 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.727 0.273 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.724 0.276 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.724 0.276 0.000
C79 Secondary malignant neoplasm of other sites
0.724 0.276 0.000
Z98 Other postsurgical states
0.723 0.277 0.000
C67.5 Bladder neck
0.723 0.277 0.000
K05 Gingivitis and periodontal diseases
0.722 0.278 0.000
I51.7 Cardiomegaly
0.721 0.279 0.000
Q80-Q89 Other congenital malformations
0.721 0.279 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.721 0.279 0.000
H05 Disorders of orbit
0.720 0.280 0.000
Z99.1 Dependence on respirator
0.719 0.281 0.000
C50-C50 Malignant neoplasm of breast
0.719 0.281 0.000
X20-X29 Contact with venomous animals and plants
0.718 0.282 0.000
C18.0 Caecum
0.717 0.283 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
H50 Other strabismus
0.715 0.285 0.000
D09 Carcinoma in situ of other and unspecified sites
0.715 0.285 0.000
H40.2 Primary angle-closure glaucoma
0.715 0.285 0.000
H43.3 Other vitreous opacities
0.714 0.286 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.714 0.286 0.000
M54.5 Low back pain
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
G58 Other mononeuropathies
0.711 0.288 0.000
M77 Other enthesopathies
0.710 0.290 0.000
M76 Enthesopathies of lower limb, excluding foot
0.709 0.291 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.709 0.291 0.000
S29.9 Unspecified injury of thorax
0.709 0.291 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.707 0.293 0.000
D05 Carcinoma in situ of breast
0.706 0.294 0.000
E20-E35 Disorders of other endocrine glands
0.706 0.294 0.000
E04 Other non-toxic goitre
0.706 0.294 0.000
S12 Fracture of neck
0.706 0.294 0.000
M50.1 Cervical disk disorder with radiculopathy
0.706 0.294 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.706 0.294 0.000
S88 Traumatic amputation of lower leg
0.705 0.295 0.000
S87 Crushing injury of lower leg
0.705 0.295 0.000
S86 Injury of muscle and tendon at lower leg level
0.705 0.295 0.000
S85 Injury of blood vessels at lower leg level
0.705 0.295 0.000
S84 Injury of nerves at lower leg level
0.705 0.295 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.705 0.295 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.705 0.295 0.000
E11 Non-insulin-dependent diabetes mellitus
0.704 0.296 0.000
F10.2 Dependence syndrome
0.703 0.297 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.703 0.297 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.702 0.298 0.000
K65 Peritonitis
0.702 0.298 0.000
E40-E46 Malnutrition
0.700 0.299 0.000
M79.7 Fibromyalgia
0.700 0.299 0.000
M53 Other dorsopathies, not elsewhere classified
0.700 0.300 0.000
Z10 Routine general health check-up of defined subpopulation
0.700 0.300 0.000
K85 Acute pancreatitis
0.700 0.300 0.000
I82 Other venous embolism and thrombosis
0.698 0.302 0.000
I50.1 Left ventricular failure
0.697 0.303 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.697 0.303 0.000
H30-H36 Disorders of choroid and retina
0.697 0.303 0.000
M54.16 Radiculopathy (Lumbar region)
0.696 0.304 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.696 0.304 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.696 0.304 0.000
C21 Malignant neoplasm of anus and anal canal
0.696 0.304 0.000
C17 Malignant neoplasm of small intestine
0.696 0.304 0.000
C23 Malignant neoplasm of gallbladder
0.696 0.304 0.000
M79.9 Soft tissue disorder, unspecified
0.696 0.304 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.696 0.304 0.000
M79.3 Panniculitis, unspecified
0.696 0.304 0.000
M79.2 Neuralgia and neuritis, unspecified
0.696 0.304 0.000
M79.1 Myalgia
0.696 0.304 0.000
G60 Hereditary and idiopathic neuropathy
0.696 0.304 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.695 0.305 0.000
H40.9 Glaucoma, unspecified
0.695 0.305 0.000
M86-M90 Other osteopathies
0.695 0.305 0.000
G54 Nerve root and plexus disorders
0.695 0.305 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.695 0.305 0.000
G52 Disorders of other cranial nerves
0.695 0.305 0.000
S89 Other and unspecified injuries of lower leg
0.695 0.305 0.000
I72 Other aneurysm
0.694 0.305 0.000
T79-T79 Certain early complications of trauma
0.694 0.306 0.000
M20-M25 Other joint disorders
0.694 0.306 0.000
S82.1 Fracture of upper end of tibia
0.694 0.306 0.000
M51.8 Other specified intervertebral disk disorders
0.693 0.307 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.693 0.307 0.000
S27 Injury of other and unspecified intrathoracic organs
0.693 0.307 0.000
S80.0 Contusion of knee
0.693 0.307 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.692 0.307 0.000
E61 Deficiency of other nutrient elements
0.692 0.308 0.000
I99 Other and unspecified disorders of circulatory system
0.692 0.308 0.000
Z99.2 Dependence on renal dialysis
0.691 0.309 0.000
K02.9 Dental caries, unspecified
0.691 0.309 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.690 0.310 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.690 0.310 0.000
G41 Status epilepticus
0.690 0.310 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.310 0.000
M13.0 Polyarthritis, unspecified
0.690 0.310 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.689 0.310 0.000
K03 Other diseases of hard tissues of teeth
0.689 0.310 0.000
K74.6 Other and unspecified cirrhosis of liver
0.689 0.311 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.689 0.311 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.689 0.311 0.000
I45.8 Other specified conduction disorders
0.689 0.311 0.000
I45.5 Other specified heart block
0.689 0.311 0.000
I45.4 Nonspecific intraventricular block
0.689 0.311 0.000
I45.3 Trifascicular block
0.689 0.311 0.000
I45.0 Right fascicular block
0.689 0.311 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.688 0.312 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.688 0.312 0.000
Z99.4 Dependence on artificial heart
0.688 0.312 0.000
Z99.0 Dependence on aspirator
0.688 0.312 0.000
M79.60 Pain in limb (Multiple sites)
0.687 0.312 0.000
I38 Endocarditis, valve unspecified
0.687 0.313 0.000
F17.1 Harmful use
0.687 0.313 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.686 0.313 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.686 0.313 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.686 0.314 0.000
C67.4 Posterior wall of bladder
0.685 0.315 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.685 0.315 0.000
X60-X84 Intentional self-harm
0.685 0.315 0.000
Z89.5 Acquired absence of leg at or below knee
0.685 0.315 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.685 0.315 0.000
C65 Malignant neoplasm of renal pelvis
0.685 0.315 0.000
F40 Phobic anxiety disorders
0.685 0.315 0.000
Z13 Special screening examination for other diseases and disorders
0.685 0.315 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.684 0.316 0.000
F80-F89 Disorders of psychological development
0.684 0.316 0.000
F70-F79 Mental retardation
0.684 0.316 0.000
F60-F69 Disorders of adult personality and behaviour
0.684 0.316 0.000
H02.9 Disorder of eyelid, unspecified
0.683 0.317 0.000
M71.3 Other bursal cyst
0.683 0.317 0.000
Z65 Problems related to other psychosocial circumstances
0.683 0.317 0.000
Z64 Problems related to certain psychosocial circumstances
0.683 0.317 0.000
Z62 Other problems related to upbringing
0.683 0.317 0.000
Z61 Problems related to negative life events in childhood
0.683 0.317 0.000
Z59 Problems related to housing and economic circumstances
0.683 0.317 0.000
Z58 Problems related to physical environment
0.683 0.317 0.000
Z56 Problems related to employment and unemployment
0.683 0.317 0.000
Z55 Problems related to education and literacy
0.683 0.317 0.000
C16.9 Stomach, unspecified
0.683 0.317 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.682 0.318 0.000
K07 Dentofacial anomalies [including malocclusion]
0.682 0.318 0.000
Z90.0 Acquired absence of part of head and neck
0.682 0.318 0.000
Z63 Other problems related to primary support group, including family circumstances
0.681 0.318 0.000
M80-M85 Disorders of bone density and structure
0.680 0.320 0.000
S02 Fracture of skull and facial bones
0.680 0.320 0.000
S82.4 Fracture of fibula alone
0.680 0.320 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.679 0.321 0.000
G51 Facial nerve disorders
0.679 0.321 0.000
E55 Vitamin D deficiency
0.678 0.321 0.000
F10.1 Harmful use
0.678 0.322 0.000
Chapter XXII Codes for special purposes
0.677 0.323 0.000
M79.62 Pain in limb (Upper arm)
0.677 0.323 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.676 0.324 0.000
C77.8 Lymph nodes of multiple regions
0.676 0.324 0.000
C18.3 Hepatic flexure
0.676 0.324 0.000
D06 Carcinoma in situ of cervix uteri
0.676 0.324 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.675 0.325 0.000
M79.88 Other specified soft tissue disorders (Other)
0.675 0.325 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.675 0.325 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.675 0.325 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.675 0.325 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.675 0.325 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.675 0.325 0.000
I88 Nonspecific lymphadenitis
0.674 0.326 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.674 0.326 0.000
C71 Malignant neoplasm of brain
0.673 0.327 0.000
K75 Other inflammatory liver diseases
0.673 0.327 0.000
S82.6 Fracture of lateral malleolus
0.672 0.328 0.000
C77.9 Lymph node, unspecified
0.672 0.328 0.000
I45.9 Conduction disorder, unspecified
0.672 0.328 0.000
I85.0 Oesophageal varices with bleeding
0.671 0.329 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.671 0.329 0.000
C80.9 Malignant neoplasm, unspecified
0.671 0.329 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.671 0.329 0.000
H55 Nystagmus and other irregular eye movements
0.670 0.330 0.000
I42.2 Other hypertrophic cardiomyopathy
0.670 0.330 0.000
K11.2 Sialoadenitis
0.670 0.330 0.000
I35 Nonrheumatic aortic valve disorders
0.670 0.330 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.669 0.331 0.000
C15.8 Overlapping lesion of oesophagus
0.669 0.331 0.000
C15.3 Upper third of oesophagus
0.669 0.331 0.000
C15.2 Abdominal part of oesophagus
0.669 0.331 0.000
C15.1 Thoracic part of oesophagus
0.669 0.331 0.000
C15.0 Cervical part of oesophagus
0.669 0.331 0.000
L60-L75 Disorders of skin appendages
0.669 0.331 0.000
H10-H13 Disorders of conjunctiva
0.669 0.331 0.000
I42.9 Cardiomyopathy, unspecified
0.669 0.331 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.669 0.331 0.000
G20-G26 Extrapyramidal and movement disorders
0.669 0.331 0.000
K04 Diseases of pulp and periapical tissues
0.667 0.333 0.000
K72 Hepatic failure, not elsewhere classified
0.667 0.333 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.667 0.333 0.000
Z09.4 Follow-up examination after treatment of fracture
0.667 0.333 0.000
Z09.3 Follow-up examination after psychotherapy
0.667 0.333 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.667 0.333 0.000
H02.5 Other disorders affecting eyelid function
0.667 0.333 0.000
K74.0 Hepatic fibrosis
0.666 0.334 0.000
S82.9 Fracture of lower leg, part unspecified
0.666 0.334 0.000
S82.7 Multiple fractures of lower leg
0.666 0.334 0.000
S82.5 Fracture of medial malleolus
0.666 0.334 0.000
S82.3 Fracture of lower end of tibia
0.666 0.334 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.665 0.335 0.000
C67.8 Overlapping lesion of bladder
0.664 0.336 0.000
C67.7 Urachus
0.664 0.336 0.000
C67.6 Ureteric orifice
0.664 0.336 0.000
C67.3 Anterior wall of bladder
0.664 0.336 0.000
C67.1 Dome of bladder
0.664 0.336 0.000
C67.0 Trigone of bladder
0.664 0.336 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.664 0.336 0.000
H02.2 Lagophthalmos
0.664 0.336 0.000
M47 Spondylosis
0.664 0.336 0.000
I51.6 Cardiovascular disease, unspecified
0.664 0.336 0.000
I51.5 Myocardial degeneration
0.664 0.336 0.000
I51.4 Myocarditis, unspecified
0.664 0.336 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.664 0.336 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.664 0.336 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.664 0.336 0.000
I51.0 Cardiac septal defect, acquired
0.664 0.336 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.664 0.336 0.000
I86.8 Varicose veins of other specified sites
0.663 0.337 0.000
T78 Adverse effects, not elsewhere classified
0.662 0.337 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.662 0.338 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.662 0.338 0.000
D04 Carcinoma in situ of skin
0.661 0.339 0.000
H43.9 Disorder of vitreous body, unspecified
0.661 0.339 0.000
H43.2 Crystalline deposits in vitreous body
0.661 0.339 0.000
H43.0 Vitreous prolapse
0.661 0.339 0.000
M54.4 Lumbago with sciatica
0.661 0.339 0.000
Chapter X Diseases of the respiratory system
0.661 0.339 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.661 0.339 0.000
F41 Other anxiety disorders
0.661 0.339 0.000
H53 Visual disturbances
0.661 0.339 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.660 0.340 0.000
Z04.8 Examination and observation for other specified reasons
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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