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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117557765
log Bayes Factor = 20.262
Chromosome 7   position 6,974,872  (GRCh37) Explore rs117557765 on Ensembl!
Variant rs117557765 is part of Cluster X0057

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I50 Heart failure
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
S60-S69 Injuries to the wrist and hand
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
D50-D53 Nutritional anaemias
0.991 0.009 0.000
E10 Insulin-dependent diabetes mellitus
0.987 0.013 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
D50 Iron deficiency anaemia
0.986 0.014 0.000
E11.9 Without complications
0.985 0.015 0.000
I50.0 Congestive heart failure
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
G90-G99 Other disorders of the nervous system
0.973 0.027 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.969 0.031 0.000
D50.8 Other iron deficiency anaemias
0.966 0.034 0.000
I50.1 Left ventricular failure
0.959 0.041 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.959 0.041 0.000
E14 Unspecified diabetes mellitus
0.959 0.041 0.000
I42 Cardiomyopathy
0.958 0.042 0.000
Chapter XIV Diseases of the genitourinary system
0.957 0.043 0.000
N17-N19 Renal failure
0.957 0.043 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.952 0.048 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.952 0.048 0.000
Chapter VII Diseases of the eye and adnexa
0.951 0.049 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.948 0.052 0.000
N18 Chronic renal failure
0.946 0.054 0.000
D50.9 Iron deficiency anaemia, unspecified
0.943 0.057 0.000
I05-I09 Chronic rheumatic heart diseases
0.942 0.058 0.000
I27 Other pulmonary heart diseases
0.940 0.060 0.000
I77 Other disorders of arteries and arterioles
0.937 0.063 0.000
E14.9 Without complications
0.933 0.067 0.000
I44 Atrioventricular and left bundle-branch block
0.931 0.069 0.000
Chapter I Certain infectious and parasitic diseases
0.927 0.073 0.000
N00-N08 Glomerular diseases
0.923 0.077 0.000
J90-J94 Other diseases of pleura
0.919 0.081 0.000
I27.2 Other secondary pulmonary hypertension
0.918 0.082 0.000
S32 Fracture of lumbar spine and pelvis
0.916 0.084 0.000
I35 Nonrheumatic aortic valve disorders
0.915 0.085 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.911 0.089 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.911 0.089 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.909 0.091 0.000
I74 Arterial embolism and thrombosis
0.909 0.091 0.000
E10.4 With neurological complications
0.909 0.091 0.000
S61 Open wound of wrist and hand
0.908 0.092 0.000
I51 Complications and ill-defined descriptions of heart disease
0.901 0.099 0.000
J20-J22 Other acute lower respiratory infections
0.899 0.101 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.896 0.104 0.000
J84 Other interstitial pulmonary diseases
0.892 0.108 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.891 0.109 0.000
W20-W49 Exposure to inanimate mechanical forces
0.888 0.112 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.888 0.112 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.886 0.114 0.000
N18.3 Chronic kidney disease, stage 3
0.884 0.116 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.884 0.116 0.000
I42.0 Dilated cardiomyopathy
0.884 0.116 0.000
I08 Multiple valve diseases
0.883 0.117 0.000
S20-S29 Injuries to the thorax
0.883 0.117 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.879 0.121 0.000
S61.0 Open wound of finger(s) without damage to nail
0.876 0.124 0.000
I50.9 Heart failure, unspecified
0.875 0.125 0.000
I73 Other peripheral vascular diseases
0.869 0.131 0.000
E10.1 With ketoacidosis
0.866 0.134 0.000
E00-E07 Disorders of thyroid gland
0.865 0.135 0.000
N19 Unspecified renal failure
0.864 0.136 0.000
N17 Acute renal failure
0.863 0.137 0.000
I60-I69 Cerebrovascular diseases
0.860 0.140 0.000
I44.2 Atrioventricular block, complete
0.858 0.142 0.000
E11.5 With peripheral circulatory complications
0.858 0.142 0.000
H55-H59 Other disorders of eye and adnexa
0.855 0.145 0.000
E10.9 Without complications
0.854 0.146 0.000
E11.4 With neurological complications
0.853 0.147 0.000
J92 Pleural plaque
0.851 0.149 0.000
J90 Pleural effusion, not elsewhere classified
0.850 0.150 0.000
Y45.0 Opioids and related analgesics
0.845 0.154 0.000
I42.9 Cardiomyopathy, unspecified
0.845 0.155 0.000
I74.5 Embolism and thrombosis of iliac artery
0.845 0.155 0.000
I77.8 Other specified disorders of arteries and arterioles
0.844 0.156 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.842 0.158 0.000
J22 Unspecified acute lower respiratory infection
0.839 0.161 0.000
I34 Nonrheumatic mitral valve disorders
0.838 0.162 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.838 0.162 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.836 0.164 0.000
S32.0 Fracture of lumbar vertebra
0.835 0.165 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.835 0.165 0.000
I33 Acute and subacute endocarditis
0.833 0.167 0.000
I08.0 Disorders of both mitral and aortic valves
0.833 0.167 0.000
G93 Other disorders of brain
0.831 0.169 0.000
E20-E35 Disorders of other endocrine glands
0.831 0.169 0.000
G40-G47 Episodic and paroxysmal disorders
0.830 0.170 0.000
S62 Fracture at wrist and hand level
0.828 0.172 0.000
I77.6 Arteritis, unspecified
0.826 0.174 0.000
N18.5 Chronic kidney disease, stage 5
0.826 0.174 0.000
E11.2 With renal complications
0.824 0.176 0.000
I35.0 Aortic (valve) stenosis
0.823 0.177 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.823 0.177 0.000
D80-D89 Certain disorders involving the immune mechanism
0.821 0.179 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.819 0.181 0.000
I73.9 Peripheral vascular disease, unspecified
0.817 0.183 0.000
J80 Adult respiratory distress syndrome
0.815 0.185 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.814 0.186 0.000
S50-S59 Injuries to the elbow and forearm
0.814 0.186 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.813 0.187 0.000
N03 Chronic nephritic syndrome
0.813 0.187 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.812 0.188 0.000
H10-H13 Disorders of conjunctiva
0.812 0.188 0.000
S69 Other and unspecified injuries of wrist and hand
0.811 0.189 0.000
H43-H45 Disorders of vitreous body and globe
0.811 0.189 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.808 0.192 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.807 0.193 0.000
E16 Other disorders of pancreatic internal secretion
0.807 0.193 0.000
E11.0 With coma
0.807 0.193 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.804 0.196 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.802 0.198 0.000
E10.5 With peripheral circulatory complications
0.800 0.200 0.000
T87 Complications peculiar to reattachment and amputation
0.800 0.200 0.000
E03 Other hypothyroidism
0.800 0.200 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.798 0.202 0.000
G95 Other diseases of spinal cord
0.797 0.203 0.000
B35-B49 Mycoses
0.797 0.203 0.000
N17.9 Acute renal failure, unspecified
0.797 0.203 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.796 0.204 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.796 0.204 0.000
I70 Atherosclerosis
0.795 0.205 0.000
I10-I15 Hypertensive diseases
0.794 0.206 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.793 0.207 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.793 0.207 0.000
N18.0 End-stage renal disease
0.792 0.208 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.792 0.208 0.000
S64 Injury of nerves at wrist and hand level
0.792 0.208 0.000
I31 Other diseases of pericardium
0.788 0.212 0.000
D55-D59 Haemolytic anaemias
0.787 0.213 0.000
E10.2 With renal complications
0.787 0.213 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.786 0.214 0.000
G40 Epilepsy
0.783 0.217 0.000
J92.0 Pleural plaque with presence of asbestos
0.783 0.217 0.000
N18.8 Other chronic renal failure
0.781 0.218 0.000
A30-A49 Other bacterial diseases
0.780 0.220 0.000
H40-H42 Glaucoma
0.779 0.221 0.000
Q60-Q64 Congenital malformations of the urinary system
0.779 0.221 0.000
E65-E68 Obesity and other hyperalimentation
0.779 0.221 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.777 0.223 0.000
D51 Vitamin B12 deficiency anaemia
0.776 0.223 0.000
I51.7 Cardiomegaly
0.775 0.225 0.000
I38 Endocarditis, valve unspecified
0.774 0.226 0.000
J09-J18 Influenza and pneumonia
0.774 0.226 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.773 0.227 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.772 0.228 0.000
T66-T78 Other and unspecified effects of external causes
0.771 0.229 0.000
T79-T79 Certain early complications of trauma
0.771 0.229 0.000
S60 Superficial injury of wrist and hand
0.771 0.229 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.770 0.230 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.770 0.230 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.769 0.231 0.000
S80-S89 Injuries to the knee and lower leg
0.769 0.231 0.000
G90 Disorders of autonomic nervous system
0.768 0.232 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.768 0.232 0.000
N05 Unspecified nephritic syndrome
0.768 0.232 0.000
I35.1 Aortic (valve) insufficiency
0.768 0.232 0.000
T82.1 Mechanical complication of cardiac electronic device
0.766 0.234 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.766 0.234 0.000
I07 Rheumatic tricuspid valve diseases
0.765 0.235 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.764 0.235 0.000
S10-S19 Injuries to the neck
0.764 0.236 0.000
J95-J99 Other diseases of the respiratory system
0.764 0.236 0.000
Y57 Other and unspecified drugs and medicaments
0.759 0.241 0.000
W29 Contact with other powered hand tools and household machinery
0.759 0.241 0.000
I51.0 Cardiac septal defect, acquired
0.759 0.241 0.000
G62 Other polyneuropathies
0.758 0.242 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.757 0.243 0.000
T90 Sequelae of injuries of head
0.757 0.243 0.000
N99-N99 Other disorders of the genitourinary system
0.756 0.244 0.000
Y52 Agents primarily affecting the cardiovascular system
0.754 0.245 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.754 0.246 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.754 0.246 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.754 0.246 0.000
E03.9 Hypothyroidism, unspecified
0.753 0.247 0.000
I36 Nonrheumatic tricuspid valve disorders
0.751 0.249 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.750 0.250 0.000
E16.2 Hypoglycaemia, unspecified
0.750 0.250 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.748 0.252 0.000
G40.9 Epilepsy, unspecified
0.748 0.252 0.000
S90-S99 Injuries to the ankle and foot
0.747 0.253 0.000
S70-S79 Injuries to the hip and thigh
0.744 0.256 0.000
I72 Other aneurysm
0.742 0.257 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.742 0.258 0.000
B15-B19 Viral hepatitis
0.741 0.259 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.741 0.259 0.000
Y00-Y09 Assault
0.739 0.261 0.000
E11.3 With ophthalmic complications
0.738 0.261 0.000
G70-G73 Diseases of myoneural junction and muscle
0.737 0.263 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.735 0.265 0.000
N03.9 Unspecified
0.734 0.266 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.733 0.266 0.000
H57 Other disorders of eye and adnexa
0.733 0.267 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.733 0.267 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.732 0.268 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.732 0.268 0.000
H30-H36 Disorders of choroid and retina
0.731 0.269 0.000
I27.0 Primary pulmonary hypertension
0.731 0.269 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.731 0.269 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.730 0.269 0.000
V10-V19 Pedal cyclist injured in transport accident
0.727 0.273 0.000
Q00-Q07 Congenital malformations of the nervous system
0.727 0.273 0.000
I27.9 Pulmonary heart disease, unspecified
0.725 0.275 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.725 0.275 0.000
T81 Complications of procedures, not elsewhere classified
0.724 0.276 0.000
S67 Crushing injury of wrist and hand
0.724 0.276 0.000
I34.0 Mitral (valve) insufficiency
0.724 0.276 0.000
E13 Other specified diabetes mellitus
0.723 0.277 0.000
N18.2 Chronic kidney disease, stage 2
0.722 0.278 0.000
N02 Recurrent and persistent haematuria
0.722 0.278 0.000
B99-B99 Other infectious diseases
0.719 0.280 0.000
V40-V49 Car occupant injured in transport accident
0.719 0.281 0.000
E40-E46 Malnutrition
0.719 0.281 0.000
I12 Hypertensive renal disease
0.718 0.282 0.000
H55 Nystagmus and other irregular eye movements
0.718 0.282 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
D52 Folate deficiency anaemia
0.716 0.284 0.000
E11.8 With unspecified complications
0.716 0.284 0.000
E11.7 With multiple complications
0.716 0.284 0.000
E11.6 With other specified complications
0.716 0.284 0.000
E11.1 With ketoacidosis
0.716 0.284 0.000
H11 Other disorders of conjunctiva
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
G96 Other disorders of central nervous system
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
I44.7 Left bundle-branch block, unspecified
0.714 0.286 0.000
I78 Diseases of capillaries
0.713 0.287 0.000
I33.0 Acute and subacute infective endocarditis
0.713 0.287 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.713 0.287 0.000
S32.5 Fracture of pubis
0.712 0.288 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.712 0.288 0.000
S65 Injury of blood vessels at wrist and hand level
0.711 0.289 0.000
H43 Disorders of vitreous body
0.711 0.289 0.000
D53 Other nutritional anaemias
0.710 0.290 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.710 0.290 0.000
N18.9 Chronic renal failure, unspecified
0.709 0.291 0.000
S29 Other and unspecified injuries of thorax
0.709 0.291 0.000
Y46.4 Iminostilbenes
0.709 0.291 0.000
E10.8 With unspecified complications
0.708 0.292 0.000
E10.7 With multiple complications
0.708 0.292 0.000
E10.6 With other specified complications
0.708 0.292 0.000
E10.0 With coma
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
I44.3 Other and unspecified atrioventricular block
0.707 0.293 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.707 0.293 0.000
D50.1 Sideropenic dysphagia
0.707 0.293 0.000
I51.4 Myocarditis, unspecified
0.704 0.296 0.000
I35.9 Aortic valve disorder, unspecified
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.702 0.298 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.700 0.300 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.301 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.697 0.302 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.697 0.302 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.697 0.302 0.000
G92 Toxic encephalopathy
0.697 0.302 0.000
G93.5 Compression of brain
0.697 0.303 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.696 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.696 0.304 0.000
S20 Superficial injury of thorax
0.695 0.305 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.695 0.305 0.000
S37 Injury of urinary and pelvic organs
0.695 0.305 0.000
S36 Injury of intra-abdominal organs
0.695 0.305 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.695 0.305 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.695 0.305 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.695 0.305 0.000
S31 Open wound of abdomen, lower back and pelvis
0.695 0.305 0.000
J81 Pulmonary oedema
0.694 0.306 0.000
A41 Other septicaemia
0.694 0.306 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.694 0.306 0.000
D86 Sarcoidosis
0.693 0.307 0.000
B65-B83 Helminthiases
0.693 0.307 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.692 0.308 0.000
V20-V29 Motorcycle rider injured in transport accident
0.691 0.308 0.000
T92 Sequelae of injuries of upper limb
0.691 0.309 0.000
W44 Foreign body entering into or through eye or natural orifice
0.691 0.309 0.000
I44.1 Atrioventricular block, second degree
0.690 0.310 0.000
Chapter XXII Codes for special purposes
0.690 0.310 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.689 0.311 0.000
G37 Other demyelinating diseases of central nervous system
0.689 0.311 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.688 0.312 0.000
S32.4 Fracture of acetabulum
0.688 0.312 0.000
I28 Other diseases of pulmonary vessels
0.688 0.312 0.000
E14.8 With unspecified complications
0.687 0.312 0.000
E14.7 With multiple complications
0.687 0.312 0.000
E14.6 With other specified complications
0.687 0.312 0.000
E14.5 With peripheral circulatory complications
0.687 0.312 0.000
E14.4 With neurological complications
0.687 0.312 0.000
E14.2 Withrenal complications
0.687 0.312 0.000
E14.1 With ketoacidosis
0.687 0.312 0.000
E14.0 With coma
0.687 0.312 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.687 0.313 0.000
I42.8 Other cardiomyopathies
0.687 0.313 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.687 0.313 0.000
I42.6 Alcoholic cardiomyopathy
0.687 0.313 0.000
I42.5 Other restrictive cardiomyopathy
0.687 0.313 0.000
I42.4 Endocardial fibroelastosis
0.687 0.313 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.687 0.313 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.686 0.314 0.000
Y46.2 Hydantoin derivatives
0.686 0.314 0.000
J30-J39 Other diseases of upper respiratory tract
0.685 0.315 0.000
N04 Nephrotic syndrome
0.684 0.316 0.000
G30-G32 Other degenerative diseases of the nervous system
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.683 0.317 0.000
Y58 Bacterial vaccines
0.683 0.317 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.683 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.683 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.683 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.683 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.683 0.317 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.682 0.318 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.682 0.318 0.000
T83.2 Mechanical complication of graft of urinary organ
0.682 0.318 0.000
G93.6 Cerebral oedema
0.682 0.318 0.000
S68 Traumatic amputation of wrist and hand
0.682 0.318 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.681 0.319 0.000
S69.9 Unspecified injury of wrist and hand
0.681 0.319 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.680 0.320 0.000
S52 Fracture of forearm
0.680 0.320 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.680 0.320 0.000
N18.1 Chronic kidney disease, stage 1
0.678 0.322 0.000
G63.2 Diabetic polyneuropathy
0.678 0.322 0.000
T82.3 Mechanical complication of other vascular grafts
0.678 0.322 0.000
G83 Other paralytic syndromes
0.678 0.322 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.677 0.323 0.000
B37 Candidiasis
0.677 0.323 0.000
E28 Ovarian dysfunction
0.677 0.323 0.000
J92.9 Pleural plaque without asbestos
0.677 0.323 0.000
Q50-Q56 Congenital malformations of genital organs
0.676 0.324 0.000
E23 Hypofunction and other disorders of pituitary gland
0.676 0.324 0.000
I09 Other rheumatic heart diseases
0.675 0.325 0.000
I06 Rheumatic aortic valve diseases
0.675 0.325 0.000
N60-N64 Disorders of breast
0.675 0.325 0.000
N10-N16 Renal tubulo-interstitial diseases
0.675 0.325 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.674 0.326 0.000
I27.8 Other specified pulmonary heart diseases
0.674 0.326 0.000
I27.1 Kyphoscoliotic heart disease
0.674 0.326 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.673 0.327 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.673 0.327 0.000
Y43 Primarily systemic agents
0.673 0.327 0.000
I77.5 Necrosis of artery
0.672 0.328 0.000
I77.4 Coeliac artery compression syndrome
0.672 0.328 0.000
I77.3 Arterial fibromuscular dysplasia
0.672 0.328 0.000
I77.2 Rupture of artery
0.672 0.328 0.000
I77.0 Arteriovenous fistula, acquired
0.672 0.328 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.670 0.329 0.000
J60-J70 Lung diseases due to external agents
0.669 0.331 0.000
W21 Striking against or struck by sports equipment
0.668 0.332 0.000
I44.6 Other and unspecified fascicular block
0.667 0.332 0.000
I44.5 Left posterior fascicular block
0.667 0.332 0.000
I44.4 Left anterior fascicular block
0.667 0.332 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.667 0.333 0.000
I60 Subarachnoid haemorrhage
0.667 0.333 0.000
E10.3 With ophthalmic complications
0.667 0.333 0.000
W00-W19 Falls
0.667 0.333 0.000
W29.9 Unspecified place
0.666 0.334 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.665 0.335 0.000
G60 Hereditary and idiopathic neuropathy
0.665 0.335 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.665 0.335 0.000
S62.7 Multiple fractures of fingers
0.665 0.335 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.664 0.336 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.664 0.336 0.000
B50-B64 Protozoal diseases
0.664 0.336 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.664 0.336 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.664 0.336 0.000
A80-A89 Viral infections of the central nervous system
0.664 0.336 0.000
A75-A79 Rickettsioses
0.664 0.336 0.000
A70-A74 Other diseases caused by chlamydiae
0.664 0.336 0.000
A65-A69 Other spirochaetal diseases
0.664 0.336 0.000
A20-A28 Certain zoonotic bacterial diseases
0.664 0.336 0.000
A15-A19 Tuberculosis
0.664 0.336 0.000
Q61 Cystic kidney disease
0.664 0.336 0.000
T87.6 Other and unspecified complications of amputation stump
0.663 0.337 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.662 0.338 0.000
N06 Isolated proteinuria with specified morphological lesion
0.662 0.338 0.000
N01 Rapidly progressive nephritic syndrome
0.662 0.338 0.000
N00 Acute nephritic syndrome
0.662 0.338 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.660 0.339 0.000
N18.4 Chronic kidney disease, stage 4
0.660 0.340 0.000
X60-X84 Intentional self-harm
0.659 0.341 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.658 0.342 0.000
E14.3 With ophthalmic complications
0.658 0.342 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.658 0.342 0.000
I05 Rheumatic mitral valve diseases
0.657 0.342 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.657 0.343 0.000
S32.3 Fracture of ilium
0.657 0.343 0.000
S32.2 Fracture of coccyx
0.657 0.343 0.000
S32.1 Fracture of sacrum
0.657 0.343 0.000
S64.3 Injury of digital nerve of thumb
0.657 0.343 0.000
G95.1 Vascular myelopathies
0.657 0.343 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.656 0.343 0.000
I71 Aortic aneurysm and dissection
0.656 0.344 0.000
H40 Glaucoma
0.656 0.344 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.655 0.345 0.000
S61.1 Open wound of finger(s) with damage to nail
0.655 0.345 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.654 0.346 0.000
E06 Thyroiditis
0.653 0.346 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.653 0.347 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.653 0.347 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.653 0.347 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.653 0.347 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.653 0.347 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.653 0.347 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.653 0.347 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.653 0.347 0.000
Q35-Q37 Cleft lip and cleft palate
0.653 0.347 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.653 0.347 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.653 0.347 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.652 0.348 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.652 0.348 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.652 0.348 0.000
G93.3 Postviral fatigue syndrome
0.652 0.348 0.000
I12.0 Hypertensive renal disease with renal failure
0.652 0.348 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.652 0.348 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.652 0.348 0.000
I74.8 Embolism and thrombosis of other arteries
0.652 0.348 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.652 0.348 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.652 0.348 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.652 0.348 0.000
I45 Other conduction disorders
0.652 0.348 0.000
G56 Mononeuropathies of upper limb
0.651 0.349 0.000
I44.0 Atrioventricular block, first degree
0.651 0.349 0.000
M86-M90 Other osteopathies
0.650 0.349 0.000
S61.7 Multiple open wounds of wrist and hand
0.650 0.349 0.000
W22 Striking against or struck by other objects
0.650 0.350 0.000
T98 Sequelae of other and unspecified effects of external causes
0.650 0.350 0.000
I51.8 Other ill-defined heart diseases
0.649 0.351 0.000
Q80-Q89 Other congenital malformations
0.649 0.351 0.000
I61 Intracerebral haemorrhage
0.649 0.351 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.649 0.351 0.000
D68 Other coagulation defects
0.647 0.353 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.647 0.353 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.647 0.353 0.000
N05.8 Other
0.646 0.354 0.000
I51.6 Cardiovascular disease, unspecified
0.646 0.354 0.000
I51.5 Myocardial degeneration
0.646 0.354 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.646 0.354 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.646 0.354 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.646 0.354 0.000
T93 Sequelae of injuries of lower limb
0.646 0.354 0.000
H46 Optic neuritis
0.645 0.355 0.000
J21 Acute bronchiolitis
0.644 0.356 0.000
I42.2 Other hypertrophic cardiomyopathy
0.644 0.356 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.644 0.356 0.000
T91 Sequelae of injuries of neck and trunk
0.643 0.356 0.000
G64 Other disorders of peripheral nervous system
0.642 0.358 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.642 0.358 0.000
H43.1 Vitreous haemorrhage
0.642 0.358 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.641 0.359 0.000
M40-M43 Deforming dorsopathies
0.640 0.360 0.000
J84.8 Other specified interstitial pulmonary diseases
0.639 0.360 0.000
J84.0 Alveolar and parietoalveolar conditions
0.639 0.360 0.000
J98 Other respiratory disorders
0.639 0.361 0.000
D56 Thalassaemia
0.639 0.361 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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