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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6650640
log Bayes Factor = 11.0513
Chromosome 18   position 31,748,225  (GRCh37) Explore rs6650640 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.998 0.002 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
S00-S09 Injuries to the head
0.992 0.008 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.989 0.011 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.984 0.016 0.000
S00 Superficial injury of head
0.979 0.021 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.979 0.021 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.976 0.024 0.000
I24 Other acute ischaemic heart diseases
0.975 0.025 0.000
E70-E90 Metabolic disorders
0.972 0.028 0.000
O60-O75 Complications of labour and delivery
0.968 0.032 0.000
S00.8 Superficial injury of other parts of head
0.965 0.035 0.000
I25.1 Atherosclerotic heart disease
0.962 0.038 0.000
I20 Angina pectoris
0.961 0.039 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.961 0.039 0.000
O00-O08 Pregnancy with abortive outcome
0.961 0.039 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.958 0.042 0.000
I24.8 Other forms of acute ischaemic heart disease
0.953 0.047 0.000
S80-S89 Injuries to the knee and lower leg
0.948 0.052 0.000
I05-I09 Chronic rheumatic heart diseases
0.947 0.053 0.000
E87.6 Hypokalaemia
0.945 0.055 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.937 0.063 0.000
S01 Open wound of head
0.937 0.063 0.000
I25.2 Old myocardial infarction
0.935 0.065 0.000
H90-H95 Other disorders of ear
0.933 0.067 0.000
H60-H62 Diseases of external ear
0.931 0.069 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.928 0.072 0.000
H65-H75 Diseases of middle ear and mastoid
0.925 0.075 0.000
I60-I69 Cerebrovascular diseases
0.920 0.080 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.917 0.083 0.000
O36 Maternal care for other known or suspected foetal problems
0.912 0.088 0.000
G90-G99 Other disorders of the nervous system
0.912 0.088 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.911 0.089 0.000
I08 Multiple valve diseases
0.909 0.091 0.000
O42 Premature rupture of membranes
0.906 0.094 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.905 0.095 0.000
E83 Disorders of mineral metabolism
0.904 0.096 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.903 0.097 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.901 0.099 0.000
I63 Cerebral infarction
0.895 0.105 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.894 0.106 0.000
H61 Other disorders of external ear
0.887 0.113 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.884 0.116 0.000
I63.9 Cerebral infarction, unspecified
0.881 0.119 0.000
O03 Spontaneous abortion
0.880 0.120 0.000
I20.9 Angina pectoris, unspecified
0.876 0.124 0.000
I20.1 Angina pectoris with documented spasm
0.874 0.126 0.000
S20-S29 Injuries to the thorax
0.871 0.129 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.871 0.129 0.000
H65 Nonsuppurative otitis media
0.870 0.130 0.000
I30-I52 Other forms of heart disease
0.866 0.134 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.856 0.144 0.000
S70-S79 Injuries to the hip and thigh
0.850 0.150 0.000
O02 Other abnormal products of conception
0.850 0.150 0.000
H93 Other disorders of ear, not elsewhere classified
0.848 0.152 0.000
E87.0 Hyperosmolality and hypernatraemia
0.848 0.152 0.000
I51 Complications and ill-defined descriptions of heart disease
0.846 0.154 0.000
I20.8 Other forms of angina pectoris
0.845 0.155 0.000
S90-S99 Injuries to the ankle and foot
0.845 0.155 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.844 0.156 0.000
O36.8 Maternal care for other specified foetal problems
0.844 0.156 0.000
O85-O92 Complications predominantly related to the puerperium
0.844 0.156 0.000
E89.0 Postprocedural hypothyroidism
0.843 0.157 0.000
O03.4 Incomplete, without complication
0.840 0.160 0.000
I08.0 Disorders of both mitral and aortic valves
0.836 0.164 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.836 0.164 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.833 0.167 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.832 0.168 0.000
E83.4 Disorders of magnesium metabolism
0.831 0.169 0.000
S00.7 Multiple superficial injuries of head
0.831 0.169 0.000
G95 Other diseases of spinal cord
0.830 0.170 0.000
S01.0 Open wound of scalp
0.829 0.171 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.826 0.174 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.825 0.175 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.824 0.176 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.822 0.178 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.819 0.181 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.815 0.185 0.000
O48 Prolonged pregnancy
0.814 0.186 0.000
I51.7 Cardiomegaly
0.811 0.189 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.811 0.189 0.000
S01.7 Multiple open wounds of head
0.810 0.190 0.000
S05 Injury of eye and orbit
0.807 0.193 0.000
S32 Fracture of lumbar spine and pelvis
0.807 0.193 0.000
G40-G47 Episodic and paroxysmal disorders
0.805 0.195 0.000
S01.8 Open wound of other parts of head
0.803 0.197 0.000
O80-O84 Delivery
0.802 0.198 0.000
I71 Aortic aneurysm and dissection
0.802 0.198 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.801 0.199 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.800 0.200 0.000
I67 Other cerebrovascular diseases
0.799 0.201 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.798 0.202 0.000
O66 Other obstructed labour
0.798 0.202 0.000
O62 Abnormalities of forces of labour
0.797 0.203 0.000
S81 Open wound of lower leg
0.795 0.205 0.000
I25.5 Ischaemic cardiomyopathy
0.794 0.206 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.792 0.208 0.000
O42.9 Premature rupture of membranes, unspecified
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.789 0.211 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.787 0.213 0.000
Q00-Q07 Congenital malformations of the nervous system
0.784 0.215 0.000
I61 Intracerebral haemorrhage
0.782 0.218 0.000
I50 Heart failure
0.780 0.220 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.780 0.220 0.000
O36.5 Maternal care for poor foetal growth
0.779 0.221 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.779 0.221 0.000
I22 Subsequent myocardial infarction
0.778 0.222 0.000
O02.1 Missed abortion
0.773 0.227 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.773 0.227 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.771 0.229 0.000
D50-D53 Nutritional anaemias
0.769 0.231 0.000
S00.1 Contusion of eyelid and periocular area
0.769 0.231 0.000
I25.3 Aneurysm of heart
0.766 0.234 0.000
Q60-Q64 Congenital malformations of the urinary system
0.765 0.235 0.000
S70 Superficial injury of hip and thigh
0.765 0.235 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.764 0.236 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.764 0.236 0.000
H93.1 Tinnitus
0.763 0.237 0.000
H61.0 Perichondritis of external ear
0.762 0.238 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.761 0.239 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.760 0.240 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.759 0.241 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.759 0.241 0.000
D69 Purpura and other haemorrhagic conditions
0.759 0.241 0.000
G51 Facial nerve disorders
0.754 0.246 0.000
O72 Postpartum haemorrhage
0.752 0.248 0.000
H61.8 Other specified disorders of external ear
0.751 0.249 0.000
I47 Paroxysmal tachycardia
0.751 0.249 0.000
E40-E46 Malnutrition
0.751 0.249 0.000
H91 Other hearing loss
0.751 0.249 0.000
O20 Haemorrhage in early pregnancy
0.751 0.249 0.000
H65.4 Other chronic nonsuppurative otitis media
0.750 0.250 0.000
S83.2 Tear of meniscus, current
0.749 0.251 0.000
E50-E64 Other nutritional deficiencies
0.748 0.252 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.747 0.253 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.747 0.253 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.745 0.255 0.000
H61.2 Impacted cerumen
0.744 0.256 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.743 0.257 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.742 0.258 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.742 0.258 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.742 0.258 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.741 0.259 0.000
S01.4 Open wound of cheek and temporomandibular area
0.740 0.260 0.000
O36.9 Maternal care for foetal problem, unspecified
0.740 0.260 0.000
S32.0 Fracture of lumbar vertebra
0.739 0.261 0.000
H65.3 Chronic mucoid otitis media
0.739 0.261 0.000
H80-H83 Diseases of inner ear
0.739 0.261 0.000
I67.9 Cerebrovascular disease, unspecified
0.738 0.262 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.736 0.264 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.736 0.264 0.000
D51 Vitamin B12 deficiency anaemia
0.734 0.266 0.000
O43 Placental disorders
0.733 0.267 0.000
G58 Other mononeuropathies
0.729 0.271 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.728 0.272 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.727 0.273 0.000
S01.5 Open wound of lip and oral cavity
0.727 0.273 0.000
S92 Fracture of foot, except ankle
0.726 0.274 0.000
G50 Disorders of trigeminal nerve
0.726 0.274 0.000
G95.9 Disease of spinal cord, unspecified
0.726 0.274 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.725 0.275 0.000
G59.0 Diabetic mononeuropathy
0.725 0.275 0.000
G93 Other disorders of brain
0.724 0.276 0.000
G70-G73 Diseases of myoneural junction and muscle
0.724 0.276 0.000
S20 Superficial injury of thorax
0.722 0.278 0.000
H69 Other disorders of Eustachian tube
0.719 0.281 0.000
I50.1 Left ventricular failure
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
O04 Medical abortion
0.717 0.283 0.000
O44 Placenta praevia
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.284 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.715 0.285 0.000
O41 Other disorders of amniotic fluid and membranes
0.714 0.286 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.714 0.286 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.714 0.286 0.000
S00.3 Superficial injury of nose
0.713 0.286 0.000
E16 Other disorders of pancreatic internal secretion
0.713 0.287 0.000
S08 Traumatic amputation of part of head
0.711 0.289 0.000
S07 Crushing injury of head
0.711 0.289 0.000
S04 Injury of cranial nerves
0.711 0.289 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.711 0.289 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.710 0.290 0.000
O45 Premature separation of placenta [abruptio placentae]
0.709 0.291 0.000
O33 Maternal care for known or suspected disproportion
0.709 0.291 0.000
O31 Complications specific to multiple gestation
0.709 0.291 0.000
S80 Superficial injury of lower leg
0.709 0.291 0.000
Chapter VII Diseases of the eye and adnexa
0.709 0.291 0.000
Chapter XX External causes of morbidity and mortality
0.707 0.293 0.000
G54 Nerve root and plexus disorders
0.706 0.294 0.000
G52 Disorders of other cranial nerves
0.705 0.294 0.000
S82 Fracture of lower leg, including ankle
0.705 0.295 0.000
O21 Excessive vomiting in pregnancy
0.705 0.295 0.000
O00 Ectopic pregnancy
0.704 0.296 0.000
S00.5 Superficial injury of lip and oral cavity
0.702 0.298 0.000
S00.4 Superficial injury of ear
0.702 0.298 0.000
I07 Rheumatic tricuspid valve diseases
0.702 0.298 0.000
S86 Injury of muscle and tendon at lower leg level
0.702 0.298 0.000
H66 Suppurative and unspecified otitis media
0.700 0.300 0.000
I24.1 Dressler's syndrome
0.699 0.301 0.000
I63.8 Other cerebral infarction
0.699 0.301 0.000
H73 Other disorders of tympanic membrane
0.698 0.302 0.000
H90 Conductive and sensorineural hearing loss
0.697 0.303 0.000
E85 Amyloidosis
0.697 0.303 0.000
E84 Cystic fibrosis
0.697 0.303 0.000
E79 Disorders of purine and pyrimidine metabolism
0.697 0.303 0.000
E77 Disorders of glycoprotein metabolism
0.697 0.303 0.000
E76 Disorders of glycosaminoglycan metabolism
0.697 0.303 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.697 0.303 0.000
E74 Other disorders of carbohydrate metabolism
0.697 0.303 0.000
E73 Lactose intolerance
0.697 0.303 0.000
E72 Other disorders of amino-acid metabolism
0.697 0.303 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.697 0.303 0.000
E70 Disorders of aromatic amino-acid metabolism
0.697 0.303 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.697 0.303 0.000
I51.8 Other ill-defined heart diseases
0.696 0.304 0.000
Q76 Congenital malformations of spine and bony thorax
0.696 0.304 0.000
D70 Agranulocytosis
0.695 0.305 0.000
T79-T79 Certain early complications of trauma
0.695 0.305 0.000
O80 Single spontaneous delivery
0.694 0.306 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.694 0.306 0.000
I30 Acute pericarditis
0.694 0.306 0.000
O74 Complications of anaesthesia during labour and delivery
0.694 0.306 0.000
O71 Other obstetric trauma
0.694 0.306 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.694 0.306 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.694 0.306 0.000
O60 Preterm delivery
0.694 0.306 0.000
E83.1 Disorders of iron metabolism
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.692 0.308 0.000
G91 Hydrocephalus
0.691 0.309 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.691 0.309 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.689 0.311 0.000
Q35-Q37 Cleft lip and cleft palate
0.689 0.311 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.689 0.311 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.689 0.311 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.689 0.311 0.000
O07 Failed attempted abortion
0.689 0.311 0.000
O06 Unspecified abortion
0.689 0.311 0.000
O05 Other abortion
0.689 0.311 0.000
O01 Hydatidiform mole
0.689 0.311 0.000
I38 Endocarditis, valve unspecified
0.688 0.311 0.000
G30-G32 Other degenerative diseases of the nervous system
0.688 0.312 0.000
S81.9 Open wound of lower leg, part unspecified
0.688 0.312 0.000
E87.4 Mixed disorder of acid-base balance
0.687 0.313 0.000
E89.3 Postprocedural hypopituitarism
0.687 0.313 0.000
Q80-Q89 Other congenital malformations
0.686 0.314 0.000
S10-S19 Injuries to the neck
0.684 0.315 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.684 0.316 0.000
O26.9 Pregnancy-related condition, unspecified
0.684 0.316 0.000
O90 Complications of the puerperium, not elsewhere classified
0.684 0.316 0.000
E83.5 Disorders of calcium metabolism
0.683 0.317 0.000
G95.1 Vascular myelopathies
0.683 0.317 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.682 0.318 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.681 0.319 0.000
S88 Traumatic amputation of lower leg
0.680 0.320 0.000
S87 Crushing injury of lower leg
0.680 0.320 0.000
S85 Injury of blood vessels at lower leg level
0.680 0.320 0.000
S84 Injury of nerves at lower leg level
0.680 0.320 0.000
H61.1 Non-infective disorders of pinna
0.679 0.321 0.000
I09 Other rheumatic heart diseases
0.679 0.321 0.000
I06 Rheumatic aortic valve diseases
0.679 0.321 0.000
G96 Other disorders of central nervous system
0.679 0.321 0.000
S09 Other and unspecified injuries of head
0.678 0.322 0.000
H93.8 Other specified disorders of ear
0.678 0.322 0.000
E89.2 Postprocedural hypoparathyroidism
0.675 0.325 0.000
H10-H13 Disorders of conjunctiva
0.674 0.326 0.000
I51.9 Heart disease, unspecified
0.674 0.326 0.000
S01.1 Open wound of eyelid and periocular area
0.673 0.326 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.672 0.328 0.000
G95.2 Cord compression, unspecified
0.672 0.328 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.671 0.329 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.671 0.329 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.670 0.330 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.669 0.331 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.669 0.331 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.667 0.333 0.000
S50-S59 Injuries to the elbow and forearm
0.666 0.334 0.000
G40 Epilepsy
0.666 0.334 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.666 0.334 0.000
O73 Retained placenta and membranes, without haemorrhage
0.664 0.336 0.000
E83.3 Disorders of phosphorus metabolism
0.664 0.336 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.663 0.336 0.000
H70 Mastoiditis and related conditions
0.663 0.336 0.000
H68 Eustachian salpingitis and obstruction
0.663 0.336 0.000
H67 Otitis media in diseases classified elsewhere
0.663 0.336 0.000
O87 Venous complications in the puerperium
0.663 0.337 0.000
S05.9 Injury of eye and orbit, part unspecified
0.661 0.339 0.000
O26.2 Pregnancy care of habitual aborter
0.661 0.339 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.660 0.340 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.659 0.340 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.659 0.340 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.659 0.341 0.000
O61 Failed induction of labour
0.659 0.341 0.000
I05 Rheumatic mitral valve diseases
0.658 0.342 0.000
O29 Complications of anaesthesia during pregnancy
0.657 0.342 0.000
O28 Abnormal findings on antenatal screening of mother
0.657 0.342 0.000
O22 Venous complications in pregnancy
0.657 0.342 0.000
O25 Malnutrition in pregnancy
0.657 0.342 0.000
S92.3 Fracture of metatarsal bone
0.657 0.343 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.657 0.343 0.000
G93.4 Encephalopathy, unspecified
0.656 0.344 0.000
O26.8 Other specified pregnancy-related conditions
0.655 0.345 0.000
I42 Cardiomyopathy
0.655 0.345 0.000
I50.0 Congestive heart failure
0.654 0.346 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.654 0.346 0.000
O36.4 Maternal care for intra-uterine death
0.654 0.346 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.654 0.346 0.000
O36.2 Maternal care for hydrops foetalis
0.654 0.346 0.000
O36.1 Maternal care for other isoimmunisation
0.654 0.346 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.654 0.346 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.654 0.346 0.000
G92 Toxic encephalopathy
0.654 0.346 0.000
H60 Otitis externa
0.653 0.346 0.000
D55-D59 Haemolytic anaemias
0.653 0.347 0.000
G90 Disorders of autonomic nervous system
0.653 0.347 0.000
H11 Other disorders of conjunctiva
0.652 0.347 0.000
O46.8 Other antepartum haemorrhage
0.652 0.348 0.000
Q65 Congenital deformities of hip
0.652 0.348 0.000
I08.9 Multiple valve disease, unspecified
0.652 0.348 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.652 0.348 0.000
Q39 Congenital malformations of oesophagus
0.651 0.348 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.650 0.350 0.000
O24 Diabetes mellitus in pregnancy
0.649 0.351 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.649 0.351 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.649 0.351 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.649 0.351 0.000
E89.5 Postprocedural testicular hypofunction
0.649 0.351 0.000
E89.4 Postprocedural ovarian failure
0.649 0.351 0.000
E89.1 Postprocedural hypoinsulinaemia
0.649 0.351 0.000
S40-S49 Injuries to the shoulder and upper arm
0.649 0.351 0.000
E20-E35 Disorders of other endocrine glands
0.649 0.351 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.649 0.351 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.648 0.352 0.000
E83.8 Other disorders of mineral metabolism
0.648 0.352 0.000
E83.2 Disorders of zinc metabolism
0.648 0.352 0.000
E83.0 Disorders of copper metabolism
0.648 0.352 0.000
S01.3 Open wound of ear
0.648 0.352 0.000
E65-E68 Obesity and other hyperalimentation
0.648 0.352 0.000
I31 Other diseases of pericardium
0.645 0.355 0.000
H55-H59 Other disorders of eye and adnexa
0.645 0.355 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.643 0.356 0.000
G57 Mononeuropathies of lower limb
0.643 0.357 0.000
O62.2 Other uterine inertia
0.643 0.357 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.643 0.357 0.000
S71 Open wound of hip and thigh
0.642 0.358 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.642 0.358 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.642 0.358 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.642 0.358 0.000
O80.0 Spontaneous vertex delivery
0.642 0.358 0.000
I95 Hypotension
0.640 0.360 0.000
G45.3 Amaurosis fugax
0.640 0.360 0.000
H74 Other disorders of middle ear and mastoid
0.639 0.360 0.000
H61.3 Acquired stenosis of external ear canal
0.639 0.361 0.000
O40 Polyhydramnios
0.637 0.363 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.637 0.363 0.000
H61.9 Disorder of external ear, unspecified
0.636 0.364 0.000
Q07 Other congenital malformations of nervous system
0.636 0.364 0.000
E87.7 Fluid overload
0.635 0.365 0.000
O30 Multiple gestation
0.635 0.365 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.634 0.366 0.000
S83.7 Injury to multiple structures of knee
0.634 0.366 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.634 0.366 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.634 0.366 0.000
S83.3 Tear of articular cartilage of knee, current
0.634 0.366 0.000
S83.1 Dislocation of knee
0.634 0.366 0.000
S83.0 Dislocation of patella
0.634 0.366 0.000
I47.1 Supraventricular tachycardia
0.634 0.366 0.000
E16.2 Hypoglycaemia, unspecified
0.633 0.367 0.000
I08.8 Other multiple valve diseases
0.633 0.367 0.000
E88 Other metabolic disorders
0.633 0.367 0.000
E87.3 Alkalosis
0.632 0.367 0.000
D69.9 Haemorrhagic condition, unspecified
0.632 0.368 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.631 0.369 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.631 0.369 0.000
O03.7 Complete or unspecified, complicated by embolism
0.631 0.369 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.631 0.369 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.631 0.369 0.000
O03.3 Incomplete, with other and unspecified complications
0.631 0.369 0.000
O03.2 Incomplete, complicated by embolism
0.631 0.369 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.631 0.369 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.631 0.369 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.631 0.369 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.630 0.370 0.000
S32.4 Fracture of acetabulum
0.630 0.370 0.000
S82.4 Fracture of fibula alone
0.629 0.371 0.000
G03 Meningitis due to other and unspecified causes
0.628 0.371 0.000
I72 Other aneurysm
0.627 0.373 0.000
S00.0 Superficial injury of scalp
0.626 0.373 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.626 0.374 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.626 0.374 0.000
H65.2 Chronic serous otitis media
0.625 0.375 0.000
S29 Other and unspecified injuries of thorax
0.625 0.375 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.625 0.375 0.000
S26 Injury of heart
0.625 0.375 0.000
S25 Injury of blood vessels of thorax
0.625 0.375 0.000
S24 Injury of nerves and spinal cord at thorax level
0.625 0.375 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.625 0.375 0.000
S21 Open wound of thorax
0.625 0.375 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.625 0.375 0.000
S37 Injury of urinary and pelvic organs
0.625 0.375 0.000
S36 Injury of intra-abdominal organs
0.625 0.375 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.625 0.375 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.625 0.375 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.625 0.375 0.000
S31 Open wound of abdomen, lower back and pelvis
0.625 0.375 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.624 0.376 0.000
H65.1 Other acute nonsuppurative otitis media
0.623 0.376 0.000
H65.0 Acute serous otitis media
0.623 0.376 0.000
H66.3 Other chronic suppurative otitis media
0.623 0.377 0.000
O86 Other puerperal infections
0.622 0.378 0.000
I52 Other heart disorders in diseases classified elsewhere
0.621 0.379 0.000
I48 Atrial fibrillation and flutter
0.621 0.379 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.621 0.379 0.000
I41 Myocarditis in diseases classified elsewhere
0.621 0.379 0.000
I40 Acute myocarditis
0.621 0.379 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.621 0.379 0.000
I37 Pulmonary valve disorders
0.621 0.379 0.000
I36 Nonrheumatic tricuspid valve disorders
0.621 0.379 0.000
I32 Pericarditis in diseases classified elsewhere
0.621 0.379 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.620 0.380 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.620 0.380 0.000
S06 Intracranial injury
0.620 0.380 0.000
O62.0 Primary inadequate contractions
0.619 0.381 0.000
O72.0 Third-stage haemorrhage
0.619 0.381 0.000
O23 Infections of genito-urinary tract in pregnancy
0.618 0.382 0.000
H91.8 Other specified hearing loss
0.618 0.382 0.000
H71 Cholesteatoma of middle ear
0.617 0.383 0.000
I51.4 Myocarditis, unspecified
0.617 0.383 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.613 0.386 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.613 0.386 0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.613 0.386 0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.613 0.386 0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.613 0.386 0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.613 0.386 0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.613 0.386 0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.613 0.386 0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.613 0.386 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.613 0.387 0.000
T18 Foreign body in alimentary tract
0.612 0.388 0.000
H72 Perforation of tympanic membrane
0.612 0.388 0.000
H92 Otalgia and effusion of ear
0.611 0.388 0.000
H95.1 Other disorders following mastoidectomy
0.611 0.389 0.000
D69.6 Thrombocytopenia, unspecified
0.610 0.390 0.000
D72 Other disorders of white blood cells
0.610 0.390 0.000
S79 Other and unspecified injuries of hip and thigh
0.610 0.390 0.000
S78 Traumatic amputation of hip and thigh
0.610 0.390 0.000
S77 Crushing injury of hip and thigh
0.610 0.390 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.610 0.390 0.000
S75 Injury of blood vessels at hip and thigh level
0.610 0.390 0.000
S74 Injury of nerves at hip and thigh level
0.610 0.390 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.610 0.390 0.000
O02.9 Abnormal product of conception, unspecified
0.609 0.391 0.000
O02.8 Other specified abnormal products of conception
0.609 0.391 0.000
H93.9 Disorder of ear, unspecified
0.608 0.392 0.000
H93.3 Disorders of acoustic nerve
0.608 0.392 0.000
H93.2 Other abnormal auditory perceptions
0.608 0.392 0.000
H93.0 Degenerative and vascular disorders of ear
0.608 0.392 0.000
G58.8 Other specified mononeuropathies
0.608 0.392 0.000
G80 Infantile cerebral palsy
0.608 0.392 0.000
S92.30 Fracture of metatarsal bone (closed)
0.607 0.393 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.607 0.393 0.000
I67.2 Cerebral atherosclerosis
0.606 0.393 0.000
I51.6 Cardiovascular disease, unspecified
0.606 0.394 0.000
I51.5 Myocardial degeneration
0.606 0.394 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.606 0.394 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.606 0.394 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.606 0.394 0.000
I51.0 Cardiac septal defect, acquired
0.606 0.394 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.606 0.394 0.000
S99 Other and unspecified injuries of ankle and foot
0.606 0.394 0.000
S98 Traumatic amputation of ankle and foot
0.606 0.394 0.000
S97 Crushing injury of ankle and foot
0.606 0.394 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.606 0.394 0.000
S95 Injury of blood vessels at ankle and foot level
0.606 0.394 0.000
S94 Injury of nerves at ankle and foot level
0.606 0.394 0.000
V10-V19 Pedal cyclist injured in transport accident
0.605 0.395 0.000
D68 Other coagulation defects
0.605 0.395 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.605 0.395 0.000
O91 Infections of breast associated with childbirth
0.605 0.395 0.000
O89 Complications of anaesthesia during the puerperium
0.605 0.395 0.000
O88 Obstetric embolism
0.605 0.395 0.000
O85 Puerperal sepsis
0.605 0.395 0.000
S32.3 Fracture of ilium
0.603 0.397 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.603 0.397 0.000
G44 Other headache syndromes
0.603 0.397 0.000
Q76.0 Spina bifida occulta
0.603 0.397 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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