TreeWAS – Variant ID: rs72884766

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I30-I52 Other forms of heart disease	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
I25 Chronic ischaemic heart disease	0.999	0.001
Chapter V Mental and behavioural disorders	0.997	0.003
Z92.2 Personal history of long-term (current) use of other medicaments	0.989	0.011
Z92 Personal history of medical treatment	0.988	0.012
I25.1 Atherosclerotic heart disease	0.988	0.012
Z95 Presence of cardiac and vascular implants and grafts	0.988	0.012
I50 Heart failure	0.987	0.013
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.986	0.014
I70-I79 Diseases of arteries, arterioles and capillaries	0.985	0.015
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.985	0.015
Chapter XV Pregnancy, childbirth and the puerperium	0.983	0.017
Chapter XXI Factors influencing health status and contact with health services	0.983	0.017
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.979	0.021
Z95.8 Presence of other cardiac and vascular implants and grafts	0.978	0.022
T36-T50 Poisoning by drugs, medicaments and biological substances	0.978	0.022
F10 Mental and behavioural disorders due to use of alcohol	0.978	0.022
I50.1 Left ventricular failure	0.977	0.023
I35 Nonrheumatic aortic valve disorders	0.972	0.028
I71 Aortic aneurysm and dissection	0.965	0.035
Chapter VIII Diseases of the ear and mastoid process	0.964	0.036
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.958	0.042
Z95.5 Presence of coronary angioplasty implant and graft	0.953	0.047
F10.1 Harmful use	0.952	0.048
Z92.1 Personal history of long-term (current) use of anticoagulants	0.952	0.048
S60-S69 Injuries to the wrist and hand	0.952	0.048
I25.8 Other forms of chronic ischaemic heart disease	0.947	0.053
F40-F48 Neurotic, stress-related and somatoform disorders	0.942	0.058
Z95.1 Presence of aortocoronary bypass graft	0.942	0.058
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.935	0.065
I95-I99 Other and unspecified disorders of the circulatory system	0.935	0.065
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.935	0.065
I42 Cardiomyopathy	0.935	0.065
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.934	0.066
I44 Atrioventricular and left bundle-branch block	0.932	0.068
Chapter XX External causes of morbidity and mortality	0.927	0.073
I05-I09 Chronic rheumatic heart diseases	0.918	0.082
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.905	0.095
I44.7 Left bundle-branch block, unspecified	0.901	0.099
I51 Complications and ill-defined descriptions of heart disease	0.898	0.102
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.896	0.104
I35.0 Aortic (valve) stenosis	0.888	0.112
O60-O75 Complications of labour and delivery	0.887	0.113
H65-H75 Diseases of middle ear and mastoid	0.884	0.116
Z99.1 Dependence on respirator	0.881	0.119
I50.9 Heart failure, unspecified	0.880	0.120
I72 Other aneurysm	0.877	0.123
I46 Cardiac arrest	0.874	0.126
Z92.4 Personal history of major surgery, not elsewhere classified	0.871	0.129
O80-O84 Delivery	0.869	0.131
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.868	0.132
I95 Hypotension	0.865	0.135
H90-H95 Other disorders of ear	0.865	0.135
I08 Multiple valve diseases	0.857	0.143
F40 Phobic anxiety disorders	0.855	0.144
S20-S29 Injuries to the thorax	0.854	0.146
F10.2 Dependence syndrome	0.850	0.150
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.849	0.151
F41 Other anxiety disorders	0.847	0.153
I42.0 Dilated cardiomyopathy	0.847	0.153
I51.7 Cardiomegaly	0.846	0.154
I25.9 Chronic ischaemic heart disease, unspecified	0.843	0.157
I31 Other diseases of pericardium	0.842	0.158
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.841	0.159
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.840	0.160
I35.1 Aortic (valve) insufficiency	0.831	0.169
I45 Other conduction disorders	0.831	0.169
S62 Fracture at wrist and hand level	0.829	0.171
S66 Injury of muscle and tendon at wrist and hand level	0.829	0.171
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.827	0.173
I95.1 Orthostatic hypotension	0.826	0.174
T51 Toxic effect of alcohol	0.826	0.174
S64 Injury of nerves at wrist and hand level	0.825	0.175
I35.2 Aortic (valve) stenosis with insufficiency	0.817	0.183
I25.5 Ischaemic cardiomyopathy	0.817	0.183
F10.0 Acute intoxication	0.816	0.184
F30-F39 Mood [affective] disorders	0.815	0.185
O20-O29 Other maternal disorders predominantly related to pregnancy	0.813	0.187
H92 Otalgia and effusion of ear	0.813	0.187
I25.0 Atherosclerotic cardiovascular disease, so described	0.812	0.188
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.811	0.189
I25.2 Old myocardial infarction	0.808	0.192
I37 Pulmonary valve disorders	0.807	0.193
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.804	0.196
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.798	0.202
Chapter XII Diseases of the skin and subcutaneous tissue	0.798	0.202
O80 Single spontaneous delivery	0.797	0.203
Z99.3 Dependence on wheelchair	0.796	0.204
F40.2 Specific (isolated) phobias	0.793	0.207
I49 Other cardiac arrhythmias	0.792	0.208
I71.0 Dissection of aorta [any part]	0.790	0.210
W00-W19 Falls	0.789	0.211
F12 Mental and behavioural disorders due to use of cannabinoids	0.788	0.212
O69 Labour and delivery complicated by umbilical cord complications	0.788	0.212
S70-S79 Injuries to the hip and thigh	0.787	0.213
O73 Retained placenta and membranes, without haemorrhage	0.787	0.213
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.784	0.216
T85 Complications of other internal prosthetic devices, implants and grafts	0.781	0.219
T51.0 Ethanol	0.781	0.219
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.781	0.219
I31.9 Disease of pericardium, unspecified	0.780	0.220
I46.0 Cardiac arrest with successful resuscitation	0.779	0.221
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.779	0.221
Z95.2 Presence of prosthetic heart valve	0.779	0.221
I21 Acute myocardial infarction	0.777	0.223
I08.0 Disorders of both mitral and aortic valves	0.776	0.224
H92.0 Otalgia	0.776	0.224
H66 Suppurative and unspecified otitis media	0.773	0.227
Z92.0 Personal history of contraception	0.773	0.227
T83.0 Mechanical complication of urinary (indwelling) catheter	0.770	0.230
I38 Endocarditis, valve unspecified	0.770	0.230
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.769	0.230
F10.3 Withdrawal state	0.769	0.230
F41.2 Mixed anxiety and depressive disorder	0.768	0.232
Z95.4 Presence of other heart-valve replacement	0.768	0.232
I20 Angina pectoris	0.765	0.235
I74 Arterial embolism and thrombosis	0.764	0.236
I22 Subsequent myocardial infarction	0.763	0.237
Z81 Family history of mental and behavioural disorders	0.762	0.238
I36 Nonrheumatic tricuspid valve disorders	0.761	0.239
T15-T19 Effects of foreign body entering through natural orifice	0.760	0.240
Chapter XXII Codes for special purposes	0.759	0.241
I98 Other disorders of circulatory system in diseases classified elsewhere	0.759	0.241
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.759	0.241
F60-F69 Disorders of adult personality and behaviour	0.756	0.244
T42.4 Benzodiazepines	0.755	0.245
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.750	0.250
T82.3 Mechanical complication of other vascular grafts	0.749	0.251
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.748	0.252
S10-S19 Injuries to the neck	0.748	0.252
V10-V19 Pedal cyclist injured in transport accident	0.748	0.252
I35.9 Aortic valve disorder, unspecified	0.747	0.253
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.745	0.255
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.743	0.257
Z91 Personal history of risk-factors, not elsewhere classified	0.742	0.258
S65 Injury of blood vessels at wrist and hand level	0.742	0.258
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.741	0.259
T39.1 4-Aminophenol derivatives	0.741	0.259
O80.0 Spontaneous vertex delivery	0.741	0.259
I30 Acute pericarditis	0.740	0.260
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.739	0.261
T79-T79 Certain early complications of trauma	0.739	0.261
D69 Purpura and other haemorrhagic conditions	0.738	0.262
I42.2 Other hypertrophic cardiomyopathy	0.732	0.268
X40-X49 Accidental poisoning by and exposure to noxious substances	0.732	0.268
Z98 Other postsurgical states	0.731	0.269
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.730	0.269
H60-H62 Diseases of external ear	0.729	0.271
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.728	0.272
O00-O08 Pregnancy with abortive outcome	0.728	0.272
I72.3 Aneurysm of iliac artery	0.727	0.273
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.725	0.275
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.725	0.275
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.725	0.275
I42.9 Cardiomyopathy, unspecified	0.722	0.278
T91 Sequelae of injuries of neck and trunk	0.719	0.281
I25.3 Aneurysm of heart	0.719	0.281
W50-W64 Exposure to animate mechanical forces	0.718	0.282
F10.4 Withdrawal state with delirium	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
O62 Abnormalities of forces of labour	0.717	0.283
I25.6 Silent myocardial ischaemia	0.716	0.284
I25.4 Coronary artery aneurysm	0.716	0.284
I71.3 Abdominal aortic aneurysm, ruptured	0.715	0.284
D69.6 Thrombocytopenia, unspecified	0.715	0.285
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.715	0.285
F70-F79 Mental retardation	0.715	0.285
O73.0 Retained placenta, without haemorrhage	0.715	0.285
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.715	0.285
T88 Other complications of surgical and medical care, not elsewhere classified	0.713	0.287
I44.6 Other and unspecified fascicular block	0.712	0.288
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.711	0.289
F80-F89 Disorders of psychological development	0.711	0.289
Z99.2 Dependence on renal dialysis	0.711	0.289
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.711	0.289
I77 Other disorders of arteries and arterioles	0.711	0.289
F41.9 Anxiety disorder, unspecified	0.710	0.290
I20.0 Unstable angina	0.710	0.290
S68 Traumatic amputation of wrist and hand	0.710	0.290
X60-X84 Intentional self-harm	0.709	0.291
Z92.9 Personal history of medical treatment, unspecified	0.709	0.291
Z92.5 Personal history of rehabilitation measures	0.709	0.291
O69.2 Labour and delivery complicated by other cord entanglement	0.708	0.292
Z84 Family history of other conditions	0.707	0.293
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.706	0.293
I42.1 Obstructive hypertrophic cardiomyopathy	0.706	0.293
I72.4 Aneurysm of artery of lower extremity	0.706	0.294
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.706	0.294
F18 Mental and behavioural disorders due to use of volatile solvents	0.706	0.294
F16 Mental and behavioural disorders due to use of hallucinogens	0.706	0.294
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.706	0.294
F14 Mental and behavioural disorders due to use of cocaine	0.706	0.294
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.706	0.294
F11 Mental and behavioural disorders due to use of opioids	0.706	0.294
X20-X29 Contact with venomous animals and plants	0.705	0.295
O85-O92 Complications predominantly related to the puerperium	0.705	0.295
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.705	0.295
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.703	0.296
T87 Complications peculiar to reattachment and amputation	0.702	0.298
T80 Complications following infusion, transfusion and therapeutic injection	0.702	0.298
T43.3 Phenothiazine antipsychotics and neuroleptics	0.701	0.298
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.701	0.299
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.701	0.299
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.701	0.299
T46 Poisoning by agents primarily affecting the cardiovascular system	0.701	0.299
T41 Poisoning by anaesthetics and therapeutic gases	0.701	0.299
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.701	0.299
T36 Poisoning by systemic antibiotics	0.701	0.299
F10.9 Unspecified mental and behavioural disorder	0.701	0.299
F10.8 Other mental and behavioural disorders	0.701	0.299
F10.7 Residual and late-onset psychotic disorder	0.701	0.299
F10.6 Amnesic syndrome	0.701	0.299
F10.5 Psychotic disorder	0.701	0.299
I05 Rheumatic mitral valve diseases	0.701	0.299
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.701	0.299
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.700	0.300
S69 Other and unspecified injuries of wrist and hand	0.699	0.301
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.699	0.301
X58-X59 Accidental exposure to other and unspecified factors	0.698	0.301
I70 Atherosclerosis	0.698	0.302
Z95.3 Presence of xenogenic heart valve	0.698	0.302
I51.9 Heart disease, unspecified	0.698	0.302
I21.0 Acute transmural myocardial infarction of anterior wall	0.697	0.303
S62.6 Fracture of other finger	0.697	0.303
H71 Cholesteatoma of middle ear	0.696	0.304
Z29 Need for other prophylactic measures	0.696	0.304
T86 Failure and rejection of transplanted organs and tissues	0.696	0.304
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.696	0.304
L20-L30 Dermatitis and eczema	0.694	0.306
I44.2 Atrioventricular block, complete	0.694	0.306
L60-L75 Disorders of skin appendages	0.694	0.306
I35.8 Other aortic valve disorders	0.692	0.308
I71.8 Aortic aneurysm of unspecified site, ruptured	0.692	0.308
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.692	0.308
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.692	0.308
I71.1 Thoracic aortic aneurysm, ruptured	0.692	0.308
I47 Paroxysmal tachycardia	0.691	0.309
I72.8 Aneurysm of other specified arteries	0.690	0.310
H80-H83 Diseases of inner ear	0.689	0.310
Q20-Q28 Congenital malformations of the circulatory system	0.689	0.311
S22 Fracture of rib(s), sternum and thoracic spine	0.688	0.312
F99-F99 Unspecified mental disorder	0.688	0.312
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.687	0.313
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.687	0.313
T82.4 Mechanical complication of vascular dialysis catheter	0.687	0.313
T82.0 Mechanical complication of heart valve prosthesis	0.687	0.313
Z89 Acquired absence of limb	0.686	0.313
L80-L99 Other disorders of the skin and subcutaneous tissue	0.686	0.314
S64.0 Injury of ulnar nerve at wrist and hand level	0.685	0.315
T59 Toxic effect of other gases, fumes and vapours	0.684	0.316
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.684	0.316
I21.1 Acute transmural myocardial infarction of inferior wall	0.681	0.319
O61 Failed induction of labour	0.679	0.320
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.678	0.322
F33 Recurrent depressive disorder	0.678	0.322
H65 Nonsuppurative otitis media	0.678	0.322
Z91.5 Personal history of self-harm	0.677	0.323
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.677	0.323
T39.0 Salicylates	0.676	0.324
F48 Other neurotic disorders	0.676	0.324
F44 Dissociative [conversion] disorders	0.676	0.324
F42 Obsessive-compulsive disorder	0.676	0.324
H72 Perforation of tympanic membrane	0.674	0.326
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.673	0.327
S62.8 Fracture of other and unspecified parts of wrist and hand	0.673	0.327
F43 Reaction to severe stress, and adjustment disorders	0.672	0.327
T43.2 Other and unspecified antidepressants	0.672	0.328
F00-F09 Organic, including symptomatic, mental disorders	0.671	0.329
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.671	0.329
Z99.9 Dependence on unspecified enabling machine and device	0.670	0.330
Z99.4 Dependence on artificial heart	0.670	0.330
Z99.0 Dependence on aspirator	0.670	0.330
I42.8 Other cardiomyopathies	0.670	0.330
I42.7 Cardiomyopathy due to drugs and other external agents	0.670	0.330
I42.6 Alcoholic cardiomyopathy	0.670	0.330
I42.5 Other restrictive cardiomyopathy	0.670	0.330
I42.4 Endocardial fibroelastosis	0.670	0.330
I42.3 Endomyocardial (eosinophilic) disease	0.670	0.330
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.669	0.331
I44.5 Left posterior fascicular block	0.668	0.332
I44.4 Left anterior fascicular block	0.668	0.332
I44.3 Other and unspecified atrioventricular block	0.668	0.332
I24 Other acute ischaemic heart diseases	0.668	0.332
I37.1 Pulmonary valve insufficiency	0.668	0.332
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.668	0.332
S29 Other and unspecified injuries of thorax	0.667	0.333
Z94 Transplanted organ and tissue status	0.666	0.334
O41 Other disorders of amniotic fluid and membranes	0.666	0.334
Z92.8 Personal history of other medical treatment	0.665	0.335
Y35-Y36 Legal intervention and operations of war	0.665	0.335
Y10-Y34 Event of undetermined intent	0.665	0.335
Y00-Y09 Assault	0.665	0.335
X85-X99 Assault	0.665	0.335
X50-X57 Overexertion, travel and privation	0.665	0.335
X30-X39 Exposure to forces of nature	0.665	0.335
X10-X19 Contact with heat and hot substances	0.665	0.335
X00-X09 Exposure to smoke, fire and flames	0.665	0.335
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.665	0.335
W75-W84 Other accidental threats to breathing	0.665	0.335
W65-W74 Accidental drowning and submersion	0.665	0.335
V98-V99 Other and unspecified transport accidents	0.665	0.335
V95-V97 Air and space transport accidents	0.665	0.335
V90-V94 Water transport accidents	0.665	0.335
V80-V89 Other land transport accidents	0.665	0.335
V70-V79 Bus occupant injured in transport accident	0.665	0.335
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.665	0.335
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.665	0.335
V40-V49 Car occupant injured in transport accident	0.665	0.335
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.665	0.335
V01-V09 Pedestrian injured in transport accident	0.665	0.335
O43 Placental disorders	0.663	0.337
T43.0 Tricyclic and tetracyclic antidepressants	0.662	0.338
S70 Superficial injury of hip and thigh	0.662	0.338
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.661	0.339
S20 Superficial injury of thorax	0.660	0.340
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.660	0.340
O75 Other complications of labour and delivery, not elsewhere classified	0.659	0.341
H66.9 Otitis media, unspecified	0.658	0.342
O23 Infections of genito-urinary tract in pregnancy	0.658	0.342
O42 Premature rupture of membranes	0.658	0.342
I09 Other rheumatic heart diseases	0.658	0.342
I06 Rheumatic aortic valve diseases	0.658	0.342
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.658	0.342
O46 Antepartum haemorrhage, not elsewhere classified	0.657	0.343
T66-T78 Other and unspecified effects of external causes	0.656	0.344
S64.3 Injury of digital nerve of thumb	0.656	0.344
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.656	0.344
S64.2 Injury of radial nerve at wrist and hand level	0.656	0.344
I33 Acute and subacute endocarditis	0.655	0.345
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.654	0.346
I78 Diseases of capillaries	0.653	0.347
O72 Postpartum haemorrhage	0.651	0.349
H69 Other disorders of Eustachian tube	0.651	0.349
I45.2 Bifascicular block	0.650	0.350
I45.6 Preexcitation syndrome	0.650	0.350
O63 Long labour	0.650	0.350
T65 Toxic effect of other and unspecified substances	0.649	0.351
T63 Toxic effect of contact with venomous animals	0.649	0.351
T62 Toxic effect of other noxious substances eaten as food	0.649	0.351
T61 Toxic effect of noxious substances eaten as seafood	0.649	0.351
T60 Toxic effect of pesticides	0.649	0.351
T57 Toxic effect of other inorganic substances	0.649	0.351
T56 Toxic effect of metals	0.649	0.351
T54 Toxic effect of corrosive substances	0.649	0.351
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.649	0.351
T52 Toxic effect of organic solvents	0.649	0.351
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.649	0.351
T58 Toxic effect of carbon monoxide	0.649	0.351
T55 Toxic effect of soaps and detergents	0.649	0.351
H74 Other disorders of middle ear and mastoid	0.648	0.351
F12.1 Harmful use	0.647	0.353
T93 Sequelae of injuries of lower limb	0.646	0.354
I08.2 Disorders of both aortic and tricuspid valves	0.645	0.355
Q50-Q56 Congenital malformations of genital organs	0.644	0.356
I51.6 Cardiovascular disease, unspecified	0.644	0.356
I51.5 Myocardial degeneration	0.644	0.356
I51.4 Myocarditis, unspecified	0.644	0.356
I51.3 Intracardiac thrombosis, not elsewhere classified	0.644	0.356
I51.2 Rupture of papillary muscle, not elsewhere classified	0.644	0.356
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.644	0.356
I51.0 Cardiac septal defect, acquired	0.644	0.356
O21 Excessive vomiting in pregnancy	0.643	0.356
M80-M85 Disorders of bone density and structure	0.643	0.357
L90 Atrophic disorders of skin	0.643	0.357
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.642	0.358
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.642	0.358
T39.4 Antirheumatics, not elsewhere classified	0.642	0.358
T39.2 Pyrazolone derivatives	0.642	0.358
Q80-Q89 Other congenital malformations	0.641	0.359
O68 Labour and delivery complicated by foetal stress [distress]	0.641	0.359
Q38-Q45 Other congenital malformations of the digestive system	0.640	0.360
I46.9 Cardiac arrest, unspecified	0.639	0.360
I49.8 Other specified cardiac arrhythmias	0.639	0.361
L27 Dermatitis due to substances taken internally	0.638	0.362
S60 Superficial injury of wrist and hand	0.638	0.362
L72 Follicular cysts of skin and subcutaneous tissue	0.637	0.363
Chapter VI Diseases of the nervous system	0.637	0.363
O74 Complications of anaesthesia during labour and delivery	0.636	0.364
O71 Other obstetric trauma	0.636	0.364
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.636	0.364
O65 Obstructed labour due to maternal pelvic abnormality	0.636	0.364
O60 Preterm delivery	0.636	0.364
H90 Conductive and sensorineural hearing loss	0.636	0.364
S67 Crushing injury of wrist and hand	0.636	0.364
S50-S59 Injuries to the elbow and forearm	0.635	0.365
I49.1 Atrial premature depolarisation	0.635	0.365
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.634	0.366
H70 Mastoiditis and related conditions	0.634	0.366
H68 Eustachian salpingitis and obstruction	0.634	0.366
H67 Otitis media in diseases classified elsewhere	0.634	0.366
I98.2 Oesophageal varices in diseases classified elsewhere	0.633	0.367
M05-M14 Inflammatory polyarthropathies	0.630	0.370
I45.1 Other and unspecified right bundle-branch block	0.630	0.370
Z70-Z76 Persons encountering health services in other circumstances	0.629	0.371
I34 Nonrheumatic mitral valve disorders	0.629	0.371
S40-S49 Injuries to the shoulder and upper arm	0.629	0.371
I72.9 Aneurysm of unspecified site	0.629	0.371
I72.6 Aneurysm and dissection of vertebral artery	0.629	0.371
I72.5 Aneurysm and dissection of other precerebral arteries	0.629	0.371
I72.2 Aneurysm of renal artery	0.629	0.371
I72.1 Aneurysm of artery of upper extremity	0.629	0.371
I72.0 Aneurysm of carotid artery	0.629	0.371
I44.0 Atrioventricular block, first degree	0.628	0.372
Z29.2 Other prophylactic chemotherapy	0.627	0.373
I46.1 Sudden cardiac death, so described	0.627	0.373
S62.60 Fracture of other finger (closed)	0.626	0.374
O94-O99 Other obstetric conditions, not elsewhere classified	0.625	0.375
T31 Burns classified according to extent of body surface involved	0.624	0.376
T83.1 Mechanical complication of other urinary devices and implants	0.623	0.377
O84 Multiple delivery	0.623	0.377
O83 Other assisted single delivery	0.623	0.377
O81 Single delivery by forceps and vacuum extractor	0.623	0.377
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.622	0.378
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.622	0.378
T83.3 Mechanical complication of intra-uterine contraceptive device	0.622	0.378
T83.2 Mechanical complication of graft of urinary organ	0.622	0.378
I49.0 Ventricular fibrillation and flutter	0.622	0.378
H66.3 Other chronic suppurative otitis media	0.622	0.378
I95.9 Hypotension, unspecified	0.621	0.379
I95.8 Other hypotension	0.620	0.380
I95.0 Idiopathic hypotension	0.620	0.380
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.620	0.380
T45.5 Anticoagulants	0.620	0.380
H94 Other disorders of ear in diseases classified elsewhere	0.620	0.380
Q00-Q07 Congenital malformations of the nervous system	0.619	0.381
L72.1 Trichilemmal cyst	0.619	0.381
V18 Pedal cyclist injured in noncollision transport accident	0.619	0.381
T90 Sequelae of injuries of head	0.618	0.382
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.616	0.384
T82.1 Mechanical complication of cardiac electronic device	0.616	0.384
O26 Maternal care for other conditions predominantly related to pregnancy	0.616	0.384
Z98.2 Presence of cerebrospinal fluid drainage device	0.615	0.385
I08.9 Multiple valve disease, unspecified	0.615	0.385
I08.8 Other multiple valve diseases	0.615	0.385
I07 Rheumatic tricuspid valve diseases	0.614	0.386
D66 Hereditary factor VIII deficiency	0.614	0.386
F40.9 Phobic anxiety disorder, unspecified	0.613	0.387
F40.8 Other phobic anxiety disorders	0.613	0.387
F40.1 Social phobias	0.613	0.387
F40.0 Agoraphobia	0.613	0.387
Z98.8 Other specified postsurgical states	0.613	0.387
I73 Other peripheral vascular diseases	0.613	0.387
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.612	0.388
S26 Injury of heart	0.612	0.388
S25 Injury of blood vessels of thorax	0.612	0.388
S24 Injury of nerves and spinal cord at thorax level	0.612	0.388
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.612	0.388
S21 Open wound of thorax	0.612	0.388
W19 Unspecified fall	0.612	0.388
V20-V29 Motorcycle rider injured in transport accident	0.612	0.388
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.611	0.389
F45 Somatoform disorders	0.611	0.389
Chapter IV Endocrine, nutritional and metabolic diseases	0.611	0.389
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.610	0.390
S27 Injury of other and unspecified intrathoracic organs	0.610	0.390
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.609	0.391
Q35-Q37 Cleft lip and cleft palate	0.609	0.391
Q30-Q34 Congenital malformations of the respiratory system	0.609	0.391
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.609	0.391
L90.5 Scar conditions and fibrosis of skin	0.608	0.392
F41.8 Other specified anxiety disorders	0.607	0.393
F41.3 Other mixed anxiety disorders	0.607	0.393
D69.3 Idiopathic thrombocytopenic purpura	0.606	0.394
F32 Depressive episode	0.606	0.394
I31.8 Other specified diseases of pericardium	0.604	0.396
I31.2 Haemopericardium, not elsewhere classified	0.604	0.396
I31.1 Chronic constrictive pericarditis	0.604	0.396
I31.0 Chronic adhesive pericarditis	0.604	0.396
I45.5 Other specified heart block	0.604	0.396
T43.9 Psychotropic drug, unspecified	0.603	0.397
T43.8 Other psychotropic drugs, not elsewhere classified	0.603	0.397
T43.6 Psychostimulants with abuse potential	0.603	0.397
T43.4 Butyrophenone and thioxanthene neuroleptics	0.603	0.397
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.603	0.397
T98 Sequelae of other and unspecified effects of external causes	0.602	0.397
T95 Sequelae of burns, corrosions and frostbite	0.602	0.397
T94 Sequelae of injuries involving multiple and unspecified body regions	0.602	0.397
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.602	0.397
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.602	0.397
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.603	0.397
Chapter I Certain infectious and parasitic diseases	0.602	0.398
Z81.8 Family history of other mental and behavioural disorders	0.602	0.398
S62.3 Fracture of other metacarpal bone	0.602	0.398

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations