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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34253858
log Bayes Factor = 17.8124
Chromosome 6   position 146,533,489  (GRCh37) Explore rs34253858 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
M06.9 Rheumatoid arthritis, unspecified
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
M54 Dorsalgia
0.991 0.009 0.000
I20-I25 Ischaemic heart diseases
0.990 0.010 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
C50-C50 Malignant neoplasm of breast
0.980 0.020 0.000
M54.5 Low back pain
0.980 0.020 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.979 0.021 0.000
I25 Chronic ischaemic heart disease
0.978 0.022 0.000
M45-M49 Spondylopathies
0.978 0.022 0.000
D00-D09 In situ neoplasms
0.978 0.022 0.000
Chapter XXI Factors influencing health status and contact with health services
0.973 0.027 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.971 0.029 0.000
I50 Heart failure
0.969 0.031 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
C50 Malignant neoplasm of breast
0.968 0.032 0.000
M47 Spondylosis
0.967 0.033 0.000
Chapter VI Diseases of the nervous system
0.962 0.038 0.000
Chapter XIV Diseases of the genitourinary system
0.961 0.039 0.000
I05-I09 Chronic rheumatic heart diseases
0.959 0.041 0.000
M47.8 Other spondylosis
0.955 0.045 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.951 0.049 0.000
E00-E07 Disorders of thyroid gland
0.946 0.054 0.000
N17-N19 Renal failure
0.940 0.060 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.937 0.063 0.000
I50.1 Left ventricular failure
0.937 0.063 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.935 0.065 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.935 0.065 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.934 0.066 0.000
M47.82 Other spondylosis (Cervical region)
0.933 0.067 0.000
Z50 Care involving use of rehabilitation procedures
0.933 0.067 0.000
I08 Multiple valve diseases
0.930 0.070 0.000
S00-S09 Injuries to the head
0.929 0.071 0.000
E65-E68 Obesity and other hyperalimentation
0.925 0.075 0.000
C50.9 Breast, unspecified
0.921 0.079 0.000
C44 Other malignant neoplasms of skin
0.920 0.080 0.000
Chapter VII Diseases of the eye and adnexa
0.919 0.081 0.000
I25.2 Old myocardial infarction
0.917 0.083 0.000
Y86 Sequelae of other accidents
0.913 0.087 0.000
H40-H42 Glaucoma
0.904 0.096 0.000
I35 Nonrheumatic aortic valve disorders
0.902 0.098 0.000
D04 Carcinoma in situ of skin
0.901 0.098 0.000
C44.4 Skin of scalp and neck
0.899 0.101 0.000
E20-E35 Disorders of other endocrine glands
0.897 0.103 0.000
M54.3 Sciatica
0.894 0.106 0.000
H40 Glaucoma
0.894 0.106 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.891 0.109 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.890 0.110 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.889 0.111 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.888 0.112 0.000
D05 Carcinoma in situ of breast
0.888 0.112 0.000
M54.59 Low back pain (Site unspecified)
0.888 0.112 0.000
I50.0 Congestive heart failure
0.885 0.115 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.878 0.122 0.000
H40.2 Primary angle-closure glaucoma
0.873 0.127 0.000
I08.0 Disorders of both mitral and aortic valves
0.872 0.128 0.000
N18 Chronic renal failure
0.872 0.128 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.872 0.128 0.000
Z42 Follow-up care involving plastic surgery
0.872 0.128 0.000
E66 Obesity
0.871 0.129 0.000
N17 Acute renal failure
0.870 0.130 0.000
I21 Acute myocardial infarction
0.870 0.130 0.000
E04 Other non-toxic goitre
0.868 0.132 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.862 0.138 0.000
Z51 Other medical care
0.860 0.140 0.000
I22 Subsequent myocardial infarction
0.859 0.141 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.859 0.141 0.000
Chapter I Certain infectious and parasitic diseases
0.859 0.141 0.000
I60-I69 Cerebrovascular diseases
0.859 0.141 0.000
D69 Purpura and other haemorrhagic conditions
0.856 0.144 0.000
I42 Cardiomyopathy
0.855 0.145 0.000
E11.4 With neurological complications
0.854 0.146 0.000
M54.57 Low back pain (Lumbosacral region)
0.854 0.146 0.000
Z43 Attention to artificial openings
0.852 0.148 0.000
S01 Open wound of head
0.852 0.148 0.000
M54.50 Low back pain (Multiple sites in spine)
0.852 0.148 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.850 0.150 0.000
C50.2 Upper-inner quadrant of breast
0.839 0.161 0.000
Z45 Adjustment and management of implanted device
0.837 0.163 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.836 0.164 0.000
M54.56 Low back pain (Lumbar region)
0.835 0.165 0.000
C50.5 Lower-outer quadrant of breast
0.833 0.167 0.000
N25-N29 Other disorders of kidney and ureter
0.833 0.167 0.000
N99-N99 Other disorders of the genitourinary system
0.831 0.169 0.000
E07 Other disorders of thyroid
0.831 0.169 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.830 0.170 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.829 0.171 0.000
Z50.5 Speech therapy
0.827 0.173 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.827 0.173 0.000
S40-S49 Injuries to the shoulder and upper arm
0.827 0.173 0.000
E04.9 Non-toxic goitre, unspecified
0.827 0.173 0.000
H40.0 Glaucoma suspect
0.826 0.174 0.000
E14 Unspecified diabetes mellitus
0.825 0.175 0.000
C50.1 Central portion of breast
0.824 0.176 0.000
M47.86 Other spondylosis (Lumbar region)
0.821 0.179 0.000
N17.9 Acute renal failure, unspecified
0.820 0.180 0.000
A30-A49 Other bacterial diseases
0.818 0.182 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.817 0.183 0.000
I35.0 Aortic (valve) stenosis
0.817 0.183 0.000
Chapter XXII Codes for special purposes
0.816 0.184 0.000
T93 Sequelae of injuries of lower limb
0.815 0.185 0.000
I25.1 Atherosclerotic heart disease
0.815 0.185 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.814 0.186 0.000
Z44 Fitting and adjustment of external prosthetic device
0.814 0.186 0.000
C64-C68 Malignant neoplasms of urinary tract
0.814 0.186 0.000
I21.9 Acute myocardial infarction, unspecified
0.812 0.188 0.000
E66.8 Other obesity
0.811 0.189 0.000
C44.5 Skin of trunk
0.810 0.190 0.000
I33 Acute and subacute endocarditis
0.810 0.190 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.808 0.192 0.000
M54.6 Pain in thoracic spine
0.807 0.192 0.000
M54.39 Sciatica (Site unspecified)
0.806 0.194 0.000
G81 Hemiplegia
0.804 0.196 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.803 0.197 0.000
E11.3 With ophthalmic complications
0.801 0.199 0.000
N18.5 Chronic kidney disease, stage 5
0.797 0.203 0.000
Z49 Care involving dialysis
0.795 0.205 0.000
D68 Other coagulation defects
0.794 0.206 0.000
D05.1 Intraductal carcinoma in situ
0.793 0.207 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.791 0.209 0.000
M06.0 Seronegative rheumatoid arthritis
0.788 0.212 0.000
T92 Sequelae of injuries of upper limb
0.787 0.213 0.000
D50-D53 Nutritional anaemias
0.787 0.213 0.000
Z50.8 Care involving use of rehabilitation procedures
0.786 0.214 0.000
Z34 Supervision of normal pregnancy
0.785 0.215 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.783 0.217 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.782 0.218 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.779 0.221 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.777 0.223 0.000
S90-S99 Injuries to the ankle and foot
0.777 0.223 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.776 0.224 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.774 0.226 0.000
S00 Superficial injury of head
0.774 0.226 0.000
A41 Other septicaemia
0.772 0.228 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.772 0.228 0.000
Z50.0 Cardiac rehabilitation
0.770 0.230 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.769 0.231 0.000
S70-S79 Injuries to the hip and thigh
0.768 0.232 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.768 0.232 0.000
M54.4 Lumbago with sciatica
0.767 0.233 0.000
W20-W49 Exposure to inanimate mechanical forces
0.767 0.233 0.000
G20-G26 Extrapyramidal and movement disorders
0.764 0.236 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.763 0.237 0.000
G90-G99 Other disorders of the nervous system
0.763 0.237 0.000
S20-S29 Injuries to the thorax
0.761 0.239 0.000
D66 Hereditary factor VIII deficiency
0.759 0.241 0.000
T91 Sequelae of injuries of neck and trunk
0.759 0.241 0.000
M54.1 Radiculopathy
0.759 0.241 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.759 0.241 0.000
D75 Other diseases of blood and blood-forming organs
0.756 0.244 0.000
V80-V89 Other land transport accidents
0.754 0.246 0.000
M54.9 Dorsalgia, unspecified
0.753 0.247 0.000
Z45.2 Adjustment and management of vascular access device
0.753 0.247 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.753 0.247 0.000
M05 Seropositive rheumatoid arthritis
0.752 0.248 0.000
M47.2 Other spondylosis with radiculopathy
0.750 0.250 0.000
H53-H54 Visual disturbances and blindness
0.750 0.250 0.000
Z51.1 Chemotherapy session for neoplasm
0.749 0.251 0.000
D04.2 Skin of ear and external auricular canal
0.749 0.251 0.000
E07.9 Disorder of thyroid, unspecified
0.748 0.252 0.000
T79-T79 Certain early complications of trauma
0.747 0.252 0.000
M86-M90 Other osteopathies
0.746 0.253 0.000
M46 Other inflammatory spondylopathies
0.746 0.254 0.000
E03 Other hypothyroidism
0.746 0.254 0.000
E50-E64 Other nutritional deficiencies
0.746 0.254 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.745 0.254 0.000
M47.9 Spondylosis, unspecified
0.745 0.255 0.000
N20-N23 Urolithiasis
0.745 0.255 0.000
Z54 Convalescence
0.744 0.256 0.000
D03 Melanoma in situ
0.743 0.257 0.000
I71 Aortic aneurysm and dissection
0.743 0.257 0.000
G81.9 Hemiplegia, unspecified
0.743 0.257 0.000
I10-I15 Hypertensive diseases
0.739 0.261 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.738 0.262 0.000
G82 Paraplegia and tetraplegia
0.738 0.262 0.000
N18.9 Chronic renal failure, unspecified
0.738 0.262 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.738 0.262 0.000
N80 Endometriosis
0.738 0.262 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.738 0.262 0.000
S01.8 Open wound of other parts of head
0.737 0.263 0.000
M91-M94 Chondropathies
0.736 0.263 0.000
E11.5 With peripheral circulatory complications
0.736 0.264 0.000
D04.7 Skin of lower limb, including hip
0.735 0.264 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.735 0.265 0.000
D70 Agranulocytosis
0.735 0.265 0.000
E28 Ovarian dysfunction
0.734 0.265 0.000
E40-E46 Malnutrition
0.734 0.266 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.734 0.266 0.000
D04.3 Skin of other and unspecified parts of face
0.731 0.269 0.000
V10-V19 Pedal cyclist injured in transport accident
0.731 0.269 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.731 0.269 0.000
I51 Complications and ill-defined descriptions of heart disease
0.730 0.270 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.730 0.270 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.730 0.270 0.000
D69.6 Thrombocytopenia, unspecified
0.729 0.271 0.000
C51-C58 Malignant neoplasms of female genital organs
0.728 0.272 0.000
I69 Sequelae of cerebrovascular disease
0.727 0.273 0.000
M07 Psoriatic and enteropathic arthropathies
0.726 0.274 0.000
I46 Cardiac arrest
0.726 0.274 0.000
S50-S59 Injuries to the elbow and forearm
0.725 0.275 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.725 0.275 0.000
N19 Unspecified renal failure
0.723 0.277 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.723 0.277 0.000
C50.4 Upper-outer quadrant of breast
0.721 0.278 0.000
Z43.2 Attention to ileostomy
0.721 0.279 0.000
I50.9 Heart failure, unspecified
0.721 0.279 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.720 0.280 0.000
Z43.3 Attention to colostomy
0.719 0.281 0.000
I31 Other diseases of pericardium
0.719 0.281 0.000
D80-D89 Certain disorders involving the immune mechanism
0.719 0.281 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.6 With other specified complications
0.717 0.283 0.000
E11.2 With renal complications
0.717 0.283 0.000
E11.1 With ketoacidosis
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
M70-M79 Other soft tissue disorders
0.717 0.283 0.000
I30 Acute pericarditis
0.716 0.284 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
S00.8 Superficial injury of other parts of head
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.4 Inflammatory polyarthropathy
0.716 0.284 0.000
M06.3 Rheumatoid nodule
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.716 0.284 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.716 0.284 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.716 0.284 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.716 0.284 0.000
W00-W19 Falls
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
I21.4 Acute subendocardial myocardial infarction
0.714 0.286 0.000
E13 Other specified diabetes mellitus
0.713 0.287 0.000
M53 Other dorsopathies, not elsewhere classified
0.713 0.287 0.000
C50.0 Nipple and areola
0.712 0.288 0.000
E66.9 Obesity, unspecified
0.711 0.289 0.000
M54.8 Other dorsalgia
0.711 0.289 0.000
M54.0 Panniculitis affecting regions of neck and back
0.711 0.289 0.000
S01.0 Open wound of scalp
0.710 0.290 0.000
I23 Certain current complications following acute myocardial infarction
0.710 0.290 0.000
X60-X84 Intentional self-harm
0.710 0.290 0.000
Y52 Agents primarily affecting the cardiovascular system
0.708 0.292 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.708 0.292 0.000
G30-G32 Other degenerative diseases of the nervous system
0.707 0.293 0.000
D69.9 Haemorrhagic condition, unspecified
0.707 0.293 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.707 0.293 0.000
E16 Other disorders of pancreatic internal secretion
0.706 0.293 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.704 0.296 0.000
D07.5 Prostate
0.703 0.297 0.000
M54.55 Low back pain (Thoracolumbar region)
0.702 0.298 0.000
M54.54 Low back pain-Thoracic
0.702 0.298 0.000
M54.53 Low back pain-Cervicothoracic
0.702 0.298 0.000
M54.52 Low back pain-Cervical
0.702 0.298 0.000
M54.51 Low back pain-Occipit-atl-axl
0.702 0.298 0.000
Z51.0 Radiotherapy session
0.702 0.298 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.702 0.298 0.000
D55-D59 Haemolytic anaemias
0.702 0.298 0.000
M11 Other crystal arthropathies
0.701 0.299 0.000
I25.6 Silent myocardial ischaemia
0.701 0.299 0.000
I25.4 Coronary artery aneurysm
0.701 0.299 0.000
I25.3 Aneurysm of heart
0.701 0.299 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.701 0.299 0.000
M49 Spondylopathies in diseases classified elsewhere
0.701 0.299 0.000
D73 Diseases of spleen
0.701 0.299 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.701 0.299 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.701 0.299 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.701 0.299 0.000
Z44.3 Fitting and adjustment of external breast prosthesis
0.701 0.299 0.000
I24 Other acute ischaemic heart diseases
0.701 0.299 0.000
M80-M85 Disorders of bone density and structure
0.700 0.300 0.000
S06 Intracranial injury
0.700 0.300 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.699 0.301 0.000
C44.1 Skin of eyelid, including canthus
0.699 0.301 0.000
N25 Disorders resulting from impaired renal tubular function
0.699 0.301 0.000
C07 Malignant neoplasm of parotid gland
0.697 0.303 0.000
E10 Insulin-dependent diabetes mellitus
0.697 0.303 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.697 0.303 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.697 0.303 0.000
G57 Mononeuropathies of lower limb
0.697 0.303 0.000
Z48 Other surgical follow-up care
0.696 0.304 0.000
T66-T78 Other and unspecified effects of external causes
0.696 0.304 0.000
M54.36 Sciatica (Lumbar region)
0.695 0.305 0.000
M40-M43 Deforming dorsopathies
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
C50.6 Axillary tail of breast
0.694 0.306 0.000
V20-V29 Motorcycle rider injured in transport accident
0.693 0.306 0.000
I42.6 Alcoholic cardiomyopathy
0.693 0.307 0.000
I42.9 Cardiomyopathy, unspecified
0.693 0.307 0.000
M47.1 Other spondylosis with myelopathy
0.693 0.307 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.693 0.307 0.000
G54 Nerve root and plexus disorders
0.693 0.307 0.000
I07 Rheumatic tricuspid valve diseases
0.692 0.308 0.000
S01.3 Open wound of ear
0.692 0.308 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.692 0.308 0.000
D04.6 Skin of upper limb, including shoulder
0.692 0.308 0.000
Z52 Donors of organs and tissues
0.691 0.308 0.000
C10 Malignant neoplasm of oropharynx
0.691 0.309 0.000
D05.0 Lobular carcinoma in situ
0.691 0.309 0.000
N26 Unspecified contracted kidney
0.690 0.310 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.690 0.310 0.000
N00-N08 Glomerular diseases
0.689 0.311 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.689 0.311 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.688 0.311 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.688 0.312 0.000
I09 Other rheumatic heart diseases
0.688 0.312 0.000
I06 Rheumatic aortic valve diseases
0.688 0.312 0.000
I05 Rheumatic mitral valve diseases
0.688 0.312 0.000
G95 Other diseases of spinal cord
0.688 0.312 0.000
C44.0 Skin of lip
0.687 0.313 0.000
I61 Intracerebral haemorrhage
0.687 0.313 0.000
A41.9 Septicaemia, unspecified
0.687 0.313 0.000
H55-H59 Other disorders of eye and adnexa
0.687 0.313 0.000
I33.0 Acute and subacute infective endocarditis
0.686 0.314 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.685 0.315 0.000
E29 Testicular dysfunction
0.685 0.315 0.000
I35.9 Aortic valve disorder, unspecified
0.684 0.315 0.000
M47.89 Other spondylosis (Site unspecified)
0.684 0.315 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.684 0.315 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.684 0.315 0.000
M47.84 Other spondylosis (Thoracic region)
0.684 0.315 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.684 0.315 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.684 0.315 0.000
Z51.3 Blood transfusion without reported diagnosis
0.684 0.316 0.000
Z31 Procreative management
0.684 0.316 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.684 0.316 0.000
N83.1 Corpus luteum cyst
0.684 0.316 0.000
G58 Other mononeuropathies
0.683 0.317 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.683 0.317 0.000
Z35 Supervision of high-risk pregnancy
0.683 0.317 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.683 0.317 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.683 0.317 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.682 0.318 0.000
S60-S69 Injuries to the wrist and hand
0.680 0.319 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.680 0.320 0.000
N83.2 Other and unspecified ovarian cysts
0.680 0.320 0.000
Q60-Q64 Congenital malformations of the urinary system
0.680 0.320 0.000
I35.1 Aortic (valve) insufficiency
0.679 0.320 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.679 0.321 0.000
N92 Excessive, frequent and irregular menstruation
0.679 0.321 0.000
Z47 Other orthopaedic follow-up care
0.678 0.322 0.000
I25.5 Ischaemic cardiomyopathy
0.678 0.322 0.000
E06 Thyroiditis
0.678 0.322 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.678 0.322 0.000
E00 Congenital iodine-deficiency syndrome
0.678 0.322 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.678 0.322 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.678 0.322 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.677 0.323 0.000
I63 Cerebral infarction
0.677 0.323 0.000
E23 Hypofunction and other disorders of pituitary gland
0.677 0.323 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.676 0.324 0.000
C44.7 Skin of lower limb, including hip
0.675 0.325 0.000
T93.2 Sequelae of other fractures of lower limb
0.675 0.325 0.000
C65 Malignant neoplasm of renal pelvis
0.675 0.325 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.675 0.325 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.674 0.326 0.000
S01.9 Open wound of head, part unspecified
0.674 0.326 0.000
E14.3 With ophthalmic complications
0.673 0.327 0.000
A49 Bacterial infection of unspecified site
0.672 0.328 0.000
D67 Hereditary factor IX deficiency
0.672 0.328 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.672 0.328 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.672 0.328 0.000
D09 Carcinoma in situ of other and unspecified sites
0.671 0.329 0.000
D51 Vitamin B12 deficiency anaemia
0.670 0.329 0.000
Q50-Q56 Congenital malformations of genital organs
0.670 0.330 0.000
Y89 Sequelae of other external causes
0.670 0.330 0.000
Y88 Sequelae of surgical and medical care as external cause
0.670 0.330 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.670 0.330 0.000
T98 Sequelae of other and unspecified effects of external causes
0.670 0.330 0.000
T95 Sequelae of burns, corrosions and frostbite
0.670 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.670 0.330 0.000
T90 Sequelae of injuries of head
0.670 0.330 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.670 0.330 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
Z50.6 Orthoptic training
0.669 0.331 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.669 0.331 0.000
Z50.3 Drug rehabilitation
0.669 0.331 0.000
Z50.2 Alcohol rehabilitation
0.669 0.331 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.669 0.331 0.000
N97 Female infertility
0.669 0.331 0.000
N80.1 Endometriosis of ovary
0.669 0.331 0.000
I35.8 Other aortic valve disorders
0.667 0.333 0.000
I08.9 Multiple valve disease, unspecified
0.667 0.333 0.000
I08.8 Other multiple valve diseases
0.667 0.333 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.667 0.333 0.000
S08 Traumatic amputation of part of head
0.666 0.334 0.000
S07 Crushing injury of head
0.666 0.334 0.000
S05 Injury of eye and orbit
0.666 0.334 0.000
S04 Injury of cranial nerves
0.666 0.334 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.666 0.334 0.000
D06 Carcinoma in situ of cervix uteri
0.665 0.334 0.000
S02 Fracture of skull and facial bones
0.665 0.335 0.000
N18.0 End-stage renal disease
0.664 0.336 0.000
M10 Gout
0.664 0.336 0.000
I38 Endocarditis, valve unspecified
0.663 0.337 0.000
E67 Other hyperalimentation
0.663 0.337 0.000
E68 Sequelae of hyperalimentation
0.663 0.337 0.000
E65 Localised adiposity
0.663 0.337 0.000
C01 Malignant neoplasm of base of tongue
0.662 0.338 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.660 0.339 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.659 0.341 0.000
C44.8 Overlapping lesion of skin
0.659 0.341 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.658 0.342 0.000
Z29 Need for other prophylactic measures
0.658 0.342 0.000
H40.5 Glaucoma secondary to other eye disorders
0.658 0.342 0.000
S80-S89 Injuries to the knee and lower leg
0.657 0.343 0.000
C43 Malignant melanoma of skin
0.656 0.343 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.656 0.344 0.000
Z34.8 Supervision of other normal pregnancy
0.655 0.345 0.000
N21 Calculus of lower urinary tract
0.655 0.345 0.000
Z45.1 Adjustment and management of infusion pump
0.655 0.345 0.000
Z51.5 Palliative care
0.653 0.347 0.000
I62 Other nontraumatic intracranial haemorrhage
0.652 0.348 0.000
C67 Malignant neoplasm of bladder
0.652 0.348 0.000
Y40 Systemic antibiotics
0.652 0.348 0.000
E22 Hyperfunction of pituitary gland
0.651 0.349 0.000
I42.0 Dilated cardiomyopathy
0.651 0.349 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.650 0.349 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.649 0.351 0.000
H42 Glaucoma in diseases classified elsewhere
0.648 0.352 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.648 0.352 0.000
M65-M68 Disorders of synovium and tendon
0.648 0.352 0.000
N95 Menopausal and other perimenopausal disorders
0.647 0.353 0.000
Z40 Prophylactic surgery
0.646 0.353 0.000
D04.9 Skin, unspecified
0.646 0.354 0.000
D04.8 Skin of other sites
0.646 0.354 0.000
D04.5 Skin of trunk
0.646 0.354 0.000
D04.4 Skin of scalp and neck
0.646 0.354 0.000
D04.1 Skin of eyelid, including canthus
0.646 0.354 0.000
D04.0 Skin of lip
0.646 0.354 0.000
Q21 Congenital malformations of cardiac septa
0.646 0.354 0.000
N86 Erosion and ectropion of cervix uteri
0.645 0.355 0.000
Y85 Sequelae of transport accidents
0.645 0.355 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.644 0.355 0.000
M54.2 Cervicalgia
0.644 0.356 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.643 0.357 0.000
E34 Other endocrine disorders
0.643 0.357 0.000
E32 Diseases of thymus
0.643 0.357 0.000
E31 Polyglandular dysfunction
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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