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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28668773
log Bayes Factor = 11.5903
Chromosome 4   position 99,523,890  (GRCh37) Explore rs28668773 on Ensembl!
Variant rs28668773 is part of Cluster X0018

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
0.999 0.001 0.000
J18 Pneumonia, organism unspecified
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.990 0.010 0.000
J18.1 Lobar pneumonia, unspecified
0.986 0.014 0.000
Chapter XIV Diseases of the genitourinary system
0.980 0.020 0.000
N17-N19 Renal failure
0.976 0.024 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.971 0.029 0.000
N17 Acute renal failure
0.968 0.032 0.000
D80-D89 Certain disorders involving the immune mechanism
0.967 0.033 0.000
J18.9 Pneumonia, unspecified
0.964 0.036 0.000
N17.9 Acute renal failure, unspecified
0.960 0.040 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.959 0.041 0.000
Chapter XX External causes of morbidity and mortality
0.956 0.044 0.000
Chapter IX Diseases of the circulatory system
0.954 0.046 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.953 0.047 0.000
J95-J99 Other diseases of the respiratory system
0.950 0.050 0.000
N40-N51 Diseases of male genital organs
0.949 0.051 0.000
D86 Sarcoidosis
0.949 0.051 0.000
S50-S59 Injuries to the elbow and forearm
0.946 0.054 0.000
S40-S49 Injuries to the shoulder and upper arm
0.943 0.057 0.000
I05-I09 Chronic rheumatic heart diseases
0.943 0.057 0.000
S00-S09 Injuries to the head
0.940 0.060 0.000
G90-G99 Other disorders of the nervous system
0.934 0.066 0.000
J90-J94 Other diseases of pleura
0.926 0.074 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.922 0.078 0.000
Chapter VIII Diseases of the ear and mastoid process
0.914 0.086 0.000
Chapter XXII Codes for special purposes
0.913 0.087 0.000
N18 Chronic renal failure
0.912 0.088 0.000
I08 Multiple valve diseases
0.911 0.089 0.000
J81 Pulmonary oedema
0.902 0.098 0.000
N18.3 Chronic kidney disease, stage 3
0.900 0.100 0.000
N48 Other disorders of penis
0.894 0.106 0.000
J98 Other respiratory disorders
0.892 0.108 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.891 0.109 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.891 0.109 0.000
S00 Superficial injury of head
0.890 0.110 0.000
S10-S19 Injuries to the neck
0.886 0.114 0.000
S52 Fracture of forearm
0.884 0.116 0.000
I30-I52 Other forms of heart disease
0.883 0.117 0.000
D86.9 Sarcoidosis, unspecified
0.883 0.117 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.883 0.117 0.000
D69 Purpura and other haemorrhagic conditions
0.881 0.119 0.000
J60-J70 Lung diseases due to external agents
0.872 0.128 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.872 0.128 0.000
G40-G47 Episodic and paroxysmal disorders
0.871 0.129 0.000
J90 Pleural effusion, not elsewhere classified
0.870 0.130 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.869 0.131 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.867 0.133 0.000
W00-W19 Falls
0.866 0.134 0.000
D60-D64 Aplastic and other anaemias
0.865 0.135 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.857 0.143 0.000
Chapter VII Diseases of the eye and adnexa
0.855 0.145 0.000
I51 Complications and ill-defined descriptions of heart disease
0.853 0.147 0.000
I05 Rheumatic mitral valve diseases
0.853 0.147 0.000
I27 Other pulmonary heart diseases
0.847 0.153 0.000
S52.6 Fracture of lower end of both ulna and radius
0.844 0.156 0.000
H35 Other retinal disorders
0.843 0.157 0.000
H30-H36 Disorders of choroid and retina
0.841 0.159 0.000
Chapter V Mental and behavioural disorders
0.840 0.160 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.840 0.160 0.000
D69.6 Thrombocytopenia, unspecified
0.838 0.162 0.000
N48.6 Balanitis xerotica obliterans
0.838 0.162 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.835 0.165 0.000
G30-G32 Other degenerative diseases of the nervous system
0.834 0.166 0.000
J11 Influenza, virus not identified
0.831 0.169 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.831 0.169 0.000
Y95 Nosocomial condition
0.830 0.170 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.830 0.170 0.000
H35.3 Degeneration of macula and posterior pole
0.828 0.172 0.000
G93 Other disorders of brain
0.827 0.173 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.826 0.174 0.000
J98.4 Other disorders of lung
0.826 0.174 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.824 0.176 0.000
J80 Adult respiratory distress syndrome
0.823 0.177 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.820 0.180 0.000
N80 Endometriosis
0.817 0.183 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.816 0.184 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.815 0.185 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.814 0.186 0.000
N83.2 Other and unspecified ovarian cysts
0.814 0.186 0.000
I51.9 Heart disease, unspecified
0.813 0.187 0.000
S42 Fracture of shoulder and upper arm
0.809 0.190 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.809 0.191 0.000
D86.0 Sarcoidosis of lung
0.805 0.195 0.000
J69 Pneumonitis due to solids and liquids
0.805 0.195 0.000
J18.0 Bronchopneumonia, unspecified
0.805 0.195 0.000
N80.1 Endometriosis of ovary
0.805 0.195 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.804 0.196 0.000
S80-S89 Injuries to the knee and lower leg
0.803 0.197 0.000
M05-M14 Inflammatory polyarthropathies
0.800 0.200 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.789 0.211 0.000
G70-G73 Diseases of myoneural junction and muscle
0.789 0.211 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.789 0.211 0.000
S00.9 Superficial injury of head, part unspecified
0.788 0.211 0.000
D86.8 Sarcoidosis of other and combined sites
0.787 0.213 0.000
H35.8 Other specified retinal disorders
0.786 0.214 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.786 0.214 0.000
U80 Agent resistant to penicillin and related antibiotics
0.786 0.214 0.000
N50 Other disorders of male genital organs
0.785 0.215 0.000
W19 Unspecified fall
0.785 0.215 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.785 0.215 0.000
H90-H95 Other disorders of ear
0.782 0.218 0.000
T63 Toxic effect of contact with venomous animals
0.782 0.218 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.781 0.219 0.000
I34 Nonrheumatic mitral valve disorders
0.779 0.221 0.000
Q50-Q56 Congenital malformations of genital organs
0.777 0.223 0.000
D86.1 Sarcoidosis of lymph nodes
0.777 0.223 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.776 0.224 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.775 0.225 0.000
G80 Infantile cerebral palsy
0.775 0.225 0.000
S00.8 Superficial injury of other parts of head
0.775 0.225 0.000
N48.4 Impotence of organic origin
0.774 0.226 0.000
J94 Other pleural conditions
0.773 0.227 0.000
I42 Cardiomyopathy
0.773 0.227 0.000
N45 Orchitis and epididymitis
0.772 0.228 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.769 0.231 0.000
X60-X84 Intentional self-harm
0.768 0.232 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.767 0.233 0.000
I27.0 Primary pulmonary hypertension
0.766 0.234 0.000
T66-T78 Other and unspecified effects of external causes
0.765 0.235 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.764 0.236 0.000
I33 Acute and subacute endocarditis
0.762 0.238 0.000
S90-S99 Injuries to the ankle and foot
0.761 0.239 0.000
S00.0 Superficial injury of scalp
0.761 0.239 0.000
V10-V19 Pedal cyclist injured in transport accident
0.761 0.239 0.000
I08.0 Disorders of both mitral and aortic valves
0.761 0.239 0.000
S20-S29 Injuries to the thorax
0.759 0.240 0.000
H65-H75 Diseases of middle ear and mastoid
0.759 0.240 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.758 0.242 0.000
I27.9 Pulmonary heart disease, unspecified
0.757 0.243 0.000
J69.0 Pneumonitis due to food and vomit
0.756 0.244 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.755 0.245 0.000
I07 Rheumatic tricuspid valve diseases
0.755 0.245 0.000
N00-N08 Glomerular diseases
0.754 0.246 0.000
G91 Hydrocephalus
0.754 0.246 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.751 0.249 0.000
G93.6 Cerebral oedema
0.751 0.249 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.749 0.251 0.000
G96 Other disorders of central nervous system
0.749 0.251 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.748 0.252 0.000
I05.9 Mitral valve disease, unspecified
0.747 0.253 0.000
W19.9 Unspecified place
0.745 0.255 0.000
H60-H62 Diseases of external ear
0.745 0.255 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.744 0.256 0.000
N99-N99 Other disorders of the genitourinary system
0.744 0.256 0.000
J00-J06 Acute upper respiratory infections
0.742 0.258 0.000
S51 Open wound of forearm
0.741 0.259 0.000
J10 Influenza due to identified influenza virus
0.740 0.260 0.000
T39.1 4-Aminophenol derivatives
0.739 0.261 0.000
S40 Superficial injury of shoulder and upper arm
0.739 0.261 0.000
S70-S79 Injuries to the hip and thigh
0.738 0.262 0.000
M06 Other rheumatoid arthritis
0.738 0.262 0.000
N17.0 Acute renal failure with tubular necrosis
0.736 0.264 0.000
G35 Multiple sclerosis
0.734 0.266 0.000
S01 Open wound of head
0.733 0.267 0.000
Q60-Q64 Congenital malformations of the urinary system
0.732 0.268 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.731 0.269 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.730 0.270 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.730 0.270 0.000
V20-V29 Motorcycle rider injured in transport accident
0.730 0.270 0.000
H35.7 Separation of retinal layers
0.727 0.273 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.727 0.273 0.000
S19 Other and unspecified injuries of neck
0.726 0.274 0.000
G40 Epilepsy
0.726 0.274 0.000
S50 Superficial injury of forearm
0.725 0.275 0.000
N25-N29 Other disorders of kidney and ureter
0.725 0.275 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.724 0.276 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.719 0.281 0.000
T63.4 Venom of other arthropods
0.719 0.281 0.000
T79-T79 Certain early complications of trauma
0.718 0.282 0.000
S05 Injury of eye and orbit
0.718 0.282 0.000
S52.8 Fracture of other parts of forearm
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
J17 Pneumonia in diseases classified elsewhere
0.716 0.283 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.716 0.283 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.716 0.283 0.000
J12 Viral pneumonia, not elsewhere classified
0.716 0.283 0.000
J14 Pneumonia due to Haemophilus influenzae
0.716 0.283 0.000
J09 Influenza due to certain identified influenza virus
0.716 0.283 0.000
N80.8 Other endometriosis
0.716 0.284 0.000
J18.8 Other pneumonia, organism unspecified
0.715 0.284 0.000
J18.2 Hypostatic pneumonia, unspecified
0.715 0.284 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.715 0.285 0.000
T90 Sequelae of injuries of head
0.714 0.286 0.000
S42.0 Fracture of clavicle
0.714 0.286 0.000
Q12 Congenital lens malformations
0.714 0.286 0.000
J93 Pneumothorax
0.713 0.287 0.000
N18.2 Chronic kidney disease, stage 2
0.713 0.287 0.000
H92 Otalgia and effusion of ear
0.711 0.289 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.710 0.290 0.000
D55-D59 Haemolytic anaemias
0.710 0.290 0.000
G47 Sleep disorders
0.710 0.290 0.000
D69.9 Haemorrhagic condition, unspecified
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
F17.1 Harmful use
0.709 0.291 0.000
T93 Sequelae of injuries of lower limb
0.708 0.292 0.000
U80.1 Methicillin resistant agent
0.707 0.293 0.000
G80.9 Infantile cerebral palsy, unspecified
0.705 0.295 0.000
W18 Other fall on same level
0.705 0.295 0.000
D69.0 Allergic purpura
0.705 0.295 0.000
G43 Migraine
0.704 0.296 0.000
G30 Alzheimer's disease
0.702 0.298 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.701 0.299 0.000
D62 Acute posthaemorrhagic anaemia
0.700 0.300 0.000
S09 Other and unspecified injuries of head
0.699 0.301 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.302 0.000
M05 Seropositive rheumatoid arthritis
0.697 0.303 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.696 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.303 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.696 0.303 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.696 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.696 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.696 0.303 0.000
T36 Poisoning by systemic antibiotics
0.696 0.303 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
I50 Heart failure
0.696 0.304 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.696 0.304 0.000
N92 Excessive, frequent and irregular menstruation
0.695 0.305 0.000
J40-J47 Chronic lower respiratory diseases
0.694 0.306 0.000
N17.8 Other acute renal failure
0.694 0.306 0.000
N17.2 Acute renal failure with medullary necrosis
0.694 0.306 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.694 0.306 0.000
D84 Other immunodeficiencies
0.694 0.306 0.000
D83 Common variable immunodeficiency
0.694 0.306 0.000
D82 Immunodeficiency associated with other major defects
0.694 0.306 0.000
D81 Combined immunodeficiencies
0.694 0.306 0.000
D80 Immunodeficiency with predominantly antibody defects
0.694 0.306 0.000
S60-S69 Injuries to the wrist and hand
0.693 0.307 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.693 0.307 0.000
N80.3 Endometriosis of pelvic peritoneum
0.693 0.307 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.692 0.308 0.000
G20-G26 Extrapyramidal and movement disorders
0.690 0.310 0.000
G82 Paraplegia and tetraplegia
0.689 0.311 0.000
M80-M85 Disorders of bone density and structure
0.689 0.311 0.000
I05.2 Mitral stenosis with insufficiency
0.689 0.311 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.689 0.311 0.000
N92.6 Irregular menstruation, unspecified
0.689 0.311 0.000
I30 Acute pericarditis
0.688 0.312 0.000
Chapter I Certain infectious and parasitic diseases
0.688 0.312 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.687 0.312 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.686 0.314 0.000
Y35-Y36 Legal intervention and operations of war
0.686 0.314 0.000
Y10-Y34 Event of undetermined intent
0.686 0.314 0.000
Y00-Y09 Assault
0.686 0.314 0.000
X85-X99 Assault
0.686 0.314 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.686 0.314 0.000
X50-X57 Overexertion, travel and privation
0.686 0.314 0.000
X30-X39 Exposure to forces of nature
0.686 0.314 0.000
X10-X19 Contact with heat and hot substances
0.686 0.314 0.000
X00-X09 Exposure to smoke, fire and flames
0.686 0.314 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.686 0.314 0.000
W75-W84 Other accidental threats to breathing
0.686 0.314 0.000
W65-W74 Accidental drowning and submersion
0.686 0.314 0.000
W50-W64 Exposure to animate mechanical forces
0.686 0.314 0.000
V98-V99 Other and unspecified transport accidents
0.686 0.314 0.000
V95-V97 Air and space transport accidents
0.686 0.314 0.000
V90-V94 Water transport accidents
0.686 0.314 0.000
V80-V89 Other land transport accidents
0.686 0.314 0.000
V70-V79 Bus occupant injured in transport accident
0.686 0.314 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.686 0.314 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.686 0.314 0.000
V40-V49 Car occupant injured in transport accident
0.686 0.314 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.686 0.314 0.000
V01-V09 Pedestrian injured in transport accident
0.686 0.314 0.000
I00-I02 Acute rheumatic fever
0.684 0.316 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.684 0.316 0.000
Q80-Q89 Other congenital malformations
0.684 0.316 0.000
Q35-Q37 Cleft lip and cleft palate
0.684 0.316 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.684 0.316 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.684 0.316 0.000
Q21 Congenital malformations of cardiac septa
0.683 0.317 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.682 0.318 0.000
S12 Fracture of neck
0.681 0.319 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.681 0.319 0.000
J96 Respiratory failure, not elsewhere classified
0.681 0.319 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.680 0.320 0.000
N46 Male infertility
0.680 0.320 0.000
N44 Torsion of testis
0.680 0.320 0.000
D86.3 Sarcoidosis of skin
0.680 0.320 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.680 0.320 0.000
S10 Superficial injury of neck
0.680 0.320 0.000
J84 Other interstitial pulmonary diseases
0.679 0.321 0.000
S52.0 Fracture of upper end of ulna
0.679 0.321 0.000
I50.0 Congestive heart failure
0.678 0.322 0.000
W20-W49 Exposure to inanimate mechanical forces
0.678 0.322 0.000
S59 Other and unspecified injuries of forearm
0.678 0.322 0.000
S58 Traumatic amputation of forearm
0.678 0.322 0.000
S57 Crushing injury of forearm
0.678 0.322 0.000
S56 Injury of muscle and tendon at forearm level
0.678 0.322 0.000
S55 Injury of blood vessels at forearm level
0.678 0.322 0.000
S54 Injury of nerves at forearm level
0.678 0.322 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.678 0.322 0.000
S43.0 Dislocation of shoulder joint
0.678 0.322 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.677 0.322 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.677 0.323 0.000
S48 Traumatic amputation of shoulder and upper arm
0.676 0.324 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.676 0.324 0.000
S44 Injury of nerves at shoulder and upper arm level
0.676 0.324 0.000
S41 Open wound of shoulder and upper arm
0.676 0.324 0.000
S47 Crushing injury of shoulder and upper arm
0.676 0.324 0.000
I09 Other rheumatic heart diseases
0.676 0.324 0.000
I06 Rheumatic aortic valve diseases
0.676 0.324 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.676 0.324 0.000
I33.0 Acute and subacute infective endocarditis
0.675 0.325 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.675 0.325 0.000
G83 Other paralytic syndromes
0.675 0.325 0.000
S08 Traumatic amputation of part of head
0.674 0.326 0.000
S07 Crushing injury of head
0.674 0.326 0.000
S04 Injury of cranial nerves
0.674 0.326 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.674 0.326 0.000
N48.0 Leukoplakia of penis
0.674 0.326 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.672 0.328 0.000
I37 Pulmonary valve disorders
0.671 0.329 0.000
D64 Other anaemias
0.671 0.329 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.670 0.329 0.000
G90 Disorders of autonomic nervous system
0.669 0.331 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.669 0.331 0.000
G92 Toxic encephalopathy
0.669 0.331 0.000
N18.5 Chronic kidney disease, stage 5
0.669 0.331 0.000
N43 Hydrocele and spermatocele
0.667 0.333 0.000
F80-F89 Disorders of psychological development
0.666 0.334 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.665 0.335 0.000
I36 Nonrheumatic tricuspid valve disorders
0.665 0.335 0.000
I51.8 Other ill-defined heart diseases
0.664 0.336 0.000
S02 Fracture of skull and facial bones
0.664 0.336 0.000
M07 Psoriatic and enteropathic arthropathies
0.662 0.338 0.000
I51.0 Cardiac septal defect, acquired
0.662 0.338 0.000
T40.6 Other and unspecified narcotics
0.661 0.339 0.000
D67 Hereditary factor IX deficiency
0.661 0.339 0.000
D66 Hereditary factor VIII deficiency
0.661 0.339 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.661 0.339 0.000
M06.9 Rheumatoid arthritis, unspecified
0.660 0.340 0.000
I51.6 Cardiovascular disease, unspecified
0.660 0.340 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.659 0.341 0.000
J98.8 Other specified respiratory disorders
0.658 0.342 0.000
H65 Nonsuppurative otitis media
0.657 0.343 0.000
N48.2 Other inflammatory disorders of penis
0.656 0.344 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.655 0.345 0.000
N18.8 Other chronic renal failure
0.654 0.346 0.000
N18.1 Chronic kidney disease, stage 1
0.654 0.346 0.000
I42.2 Other hypertrophic cardiomyopathy
0.654 0.346 0.000
I08.9 Multiple valve disease, unspecified
0.653 0.347 0.000
I08.8 Other multiple valve diseases
0.653 0.347 0.000
Q00-Q07 Congenital malformations of the nervous system
0.652 0.348 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.650 0.350 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.650 0.350 0.000
I42.9 Cardiomyopathy, unspecified
0.650 0.350 0.000
S01.0 Open wound of scalp
0.649 0.351 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.649 0.351 0.000
N48.1 Balanoposthitis
0.648 0.352 0.000
Q27 Other congenital malformations of peripheral vascular system
0.648 0.352 0.000
Q23 Congenital malformations of aortic and mitral valves
0.646 0.354 0.000
S42.00 Fracture of clavicle (closed)
0.646 0.354 0.000
H92.1 Otorrhoea
0.646 0.354 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.646 0.354 0.000
S32 Fracture of lumbar spine and pelvis
0.646 0.354 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.645 0.354 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.644 0.356 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.643 0.357 0.000
Q12.0 Congenital cataract
0.643 0.357 0.000
H53-H54 Visual disturbances and blindness
0.641 0.359 0.000
N48.9 Disorder of penis, unspecified
0.641 0.359 0.000
N48.5 Ulcer of penis
0.641 0.359 0.000
N48.3 Priapism
0.641 0.359 0.000
I60-I69 Cerebrovascular diseases
0.640 0.360 0.000
J98.9 Respiratory disorder, unspecified
0.640 0.360 0.000
J98.6 Disorders of diaphragm
0.640 0.360 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.640 0.360 0.000
J98.3 Compensatory emphysema
0.640 0.360 0.000
J98.2 Interstitial emphysema
0.640 0.360 0.000
D61 Other aplastic anaemias
0.640 0.360 0.000
D50-D53 Nutritional anaemias
0.640 0.360 0.000
I34.0 Mitral (valve) insufficiency
0.639 0.361 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.639 0.361 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.639 0.361 0.000
T46.7 Peripheral vasodilators
0.639 0.361 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.639 0.361 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.639 0.361 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.639 0.361 0.000
T46.1 Calcium-channel blockers
0.639 0.361 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.639 0.361 0.000
I28 Other diseases of pulmonary vessels
0.639 0.361 0.000
I26 Pulmonary embolism
0.639 0.361 0.000
W08 Fall involving other furniture
0.639 0.361 0.000
J94.2 Haemothorax
0.638 0.361 0.000
S00.7 Multiple superficial injuries of head
0.638 0.362 0.000
S00.5 Superficial injury of lip and oral cavity
0.638 0.362 0.000
S00.4 Superficial injury of ear
0.638 0.362 0.000
S00.3 Superficial injury of nose
0.638 0.362 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.638 0.362 0.000
N90.6 Hypertrophy of vulva
0.638 0.362 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.638 0.362 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.638 0.362 0.000
I05.0 Mitral stenosis
0.636 0.364 0.000
M40-M43 Deforming dorsopathies
0.636 0.364 0.000
S17 Crushing injury of neck
0.635 0.364 0.000
S15 Injury of blood vessels at neck level
0.635 0.364 0.000
S14 Injury of nerves and spinal cord at neck level
0.635 0.364 0.000
S11 Open wound of neck
0.635 0.364 0.000
S18 Traumatic amputation at neck level
0.635 0.364 0.000
S16 Injury of muscle and tendon at neck level
0.635 0.364 0.000
S82 Fracture of lower leg, including ankle
0.634 0.366 0.000
S52.9 Fracture of forearm, part unspecified
0.634 0.366 0.000
S52.7 Multiple fractures of forearm
0.634 0.366 0.000
S52.4 Fracture of shafts of both ulna and radius
0.634 0.366 0.000
S52.3 Fracture of shaft of radius
0.634 0.366 0.000
S52.2 Fracture of shaft of ulna
0.634 0.366 0.000
I46 Cardiac arrest
0.633 0.367 0.000
I52 Other heart disorders in diseases classified elsewhere
0.633 0.367 0.000
I48 Atrial fibrillation and flutter
0.633 0.367 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.633 0.367 0.000
I41 Myocarditis in diseases classified elsewhere
0.633 0.367 0.000
I40 Acute myocarditis
0.633 0.367 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.633 0.367 0.000
I32 Pericarditis in diseases classified elsewhere
0.633 0.367 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.633 0.367 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.633 0.367 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.633 0.367 0.000
Y98 Lifestyle-related condition
0.633 0.367 0.000
Y97 Environmental-pollution-related condition
0.633 0.367 0.000
Y96 Work-related condition
0.633 0.367 0.000
D69.8 Other specified haemorrhagic conditions
0.632 0.368 0.000
D69.5 Secondary thrombocytopenia
0.632 0.368 0.000
D69.4 Other primary thrombocytopenia
0.632 0.368 0.000
D69.2 Other nonthrombocytopenic purpura
0.632 0.368 0.000
D69.1 Qualitative platelet defects
0.632 0.368 0.000
T92 Sequelae of injuries of upper limb
0.631 0.369 0.000
T40.2 Other opioids
0.631 0.369 0.000
S42.4 Fracture of lower end of humerus
0.630 0.370 0.000
X78 Intentional self-harm by sharp object
0.628 0.372 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.628 0.372 0.000
J92 Pleural plaque
0.628 0.372 0.000
G93.4 Encephalopathy, unspecified
0.628 0.372 0.000
T39.0 Salicylates
0.628 0.372 0.000
W06 Fall involving bed
0.627 0.373 0.000
N41 Inflammatory diseases of prostate
0.626 0.374 0.000
J70 Respiratory conditions due to other external agents
0.625 0.374 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.625 0.374 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.625 0.374 0.000
J66 Airway disease due to specific organic dust
0.625 0.374 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.625 0.374 0.000
J62 Pneumoconiosis due to dust containing silica
0.625 0.374 0.000
J65 Pneumoconiosis associated with tuberculosis
0.625 0.374 0.000
J64 Unspecified pneumoconiosis
0.625 0.374 0.000
J60 Coalworker's pneumoconiosis
0.625 0.374 0.000
G41 Status epilepticus
0.625 0.375 0.000
J30-J39 Other diseases of upper respiratory tract
0.625 0.375 0.000
W19.3 Sports and athletics area
0.625 0.375 0.000
G91.9 Hydrocephalus, unspecified
0.625 0.375 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.624 0.376 0.000
H35.6 Retinal haemorrhage
0.624 0.376 0.000
G93.9 Disorder of brain, unspecified
0.624 0.376 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.623 0.377 0.000
G93.8 Other specified disorders of brain
0.623 0.377 0.000
T65 Toxic effect of other and unspecified substances
0.623 0.377 0.000
T62 Toxic effect of other noxious substances eaten as food
0.623 0.377 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.623 0.377 0.000
T60 Toxic effect of pesticides
0.623 0.377 0.000
T59 Toxic effect of other gases, fumes and vapours
0.623 0.377 0.000
T57 Toxic effect of other inorganic substances
0.623 0.377 0.000
T56 Toxic effect of metals
0.623 0.377 0.000
T54 Toxic effect of corrosive substances
0.623 0.377 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.623 0.377 0.000
T52 Toxic effect of organic solvents
0.623 0.377 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.623 0.377 0.000
T58 Toxic effect of carbon monoxide
0.623 0.377 0.000
T55 Toxic effect of soaps and detergents
0.623 0.377 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.623 0.377 0.000
G95 Other diseases of spinal cord
0.622 0.377 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.622 0.378 0.000
T98 Sequelae of other and unspecified effects of external causes
0.622 0.378 0.000
T95 Sequelae of burns, corrosions and frostbite
0.622 0.378 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.622 0.378 0.000
T91 Sequelae of injuries of neck and trunk
0.622 0.378 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.622 0.378 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.622 0.378 0.000
H35.0 Background retinopathy and retinal vascular changes
0.621 0.378 0.000
S81 Open wound of lower leg
0.621 0.379 0.000
W17 Other fall from one level to another
0.621 0.379 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.621 0.379 0.000
W15 Fall from cliff
0.621 0.379 0.000
W14 Fall from tree
0.621 0.379 0.000
W12 Fall on and from scaffolding
0.621 0.379 0.000
W11 Fall on and from ladder
0.621 0.379 0.000
W09 Fall involving playground equipment
0.621 0.379 0.000
W05 Fall involving wheelchair
0.621 0.379 0.000
W04 Fall while being carried or supported by other persons
0.621 0.379 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.621 0.379 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.621 0.379 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.621 0.379 0.000
W00 Fall on same level involving ice and snow
0.621 0.379 0.000
I07.1 Tricuspid insufficiency
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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