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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78811453
log Bayes Factor = 17.7026
Chromosome 5   position 68,822,698  (GRCh37) Explore rs78811453 on Ensembl!
Variant rs78811453 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
I10-I15 Hypertensive diseases
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
I10 Essential (primary) hypertension
0.996 0.004 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.991 0.009 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.989 0.011 0.000
I60-I69 Cerebrovascular diseases
0.988 0.012 0.000
M70-M79 Other soft tissue disorders
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.985 0.015 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.981 0.019 0.000
N17-N19 Renal failure
0.976 0.024 0.000
I45 Other conduction disorders
0.975 0.025 0.000
I69 Sequelae of cerebrovascular disease
0.974 0.026 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.970 0.030 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.970 0.030 0.000
I35 Nonrheumatic aortic valve disorders
0.968 0.032 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.966 0.034 0.000
H25-H28 Disorders of lens
0.963 0.037 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.963 0.037 0.000
N18 Chronic renal failure
0.961 0.039 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.960 0.040 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.959 0.041 0.000
R00 Abnormalities of heart beat
0.958 0.042 0.000
M05-M14 Inflammatory polyarthropathies
0.955 0.045 0.000
R00.1 Bradycardia, unspecified
0.954 0.046 0.000
F30-F39 Mood [affective] disorders
0.952 0.048 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.951 0.049 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.950 0.050 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.950 0.050 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.949 0.051 0.000
I60 Subarachnoid haemorrhage
0.946 0.054 0.000
N73 Other female pelvic inflammatory diseases
0.943 0.057 0.000
G20-G26 Extrapyramidal and movement disorders
0.942 0.058 0.000
N73.6 Female pelvic peritoneal adhesions
0.934 0.066 0.000
R02 Gangrene, not elsewhere classified
0.933 0.067 0.000
I42 Cardiomyopathy
0.928 0.072 0.000
G81 Hemiplegia
0.923 0.076 0.000
B95-B98 Bacterial, viral and other infectious agents
0.923 0.077 0.000
I35.0 Aortic (valve) stenosis
0.921 0.079 0.000
I05-I09 Chronic rheumatic heart diseases
0.919 0.081 0.000
R47-R49 Symptoms and signs involving speech and voice
0.918 0.082 0.000
N18.9 Chronic renal failure, unspecified
0.918 0.082 0.000
N80 Endometriosis
0.918 0.082 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.917 0.083 0.000
Chapter II Neoplasms
0.914 0.086 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.914 0.086 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.911 0.089 0.000
S20-S29 Injuries to the thorax
0.909 0.091 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.908 0.092 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.906 0.094 0.000
N60-N64 Disorders of breast
0.903 0.097 0.000
M79.0 Rheumatism, unspecified
0.899 0.101 0.000
I45.1 Other and unspecified right bundle-branch block
0.895 0.105 0.000
G81.9 Hemiplegia, unspecified
0.893 0.107 0.000
G20 Parkinson's disease
0.890 0.110 0.000
I51 Complications and ill-defined descriptions of heart disease
0.889 0.111 0.000
H26 Other cataract
0.886 0.114 0.000
N87 Dysplasia of cervix uteri
0.886 0.114 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.885 0.115 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.885 0.115 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.883 0.117 0.000
N80.3 Endometriosis of pelvic peritoneum
0.879 0.121 0.000
S60-S69 Injuries to the wrist and hand
0.879 0.121 0.000
Chapter VIII Diseases of the ear and mastoid process
0.879 0.121 0.000
M13 Other arthritis
0.878 0.122 0.000
M45-M49 Spondylopathies
0.878 0.122 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.875 0.125 0.000
L20-L30 Dermatitis and eczema
0.875 0.125 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.874 0.126 0.000
H30-H36 Disorders of choroid and retina
0.873 0.127 0.000
N18.3 Chronic kidney disease, stage 3
0.873 0.127 0.000
H04 Disorders of lachrymal system
0.872 0.128 0.000
M75 Shoulder lesions
0.871 0.129 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.871 0.129 0.000
H02 Other disorders of eyelid
0.866 0.134 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.866 0.134 0.000
I45.9 Conduction disorder, unspecified
0.864 0.136 0.000
G90-G99 Other disorders of the nervous system
0.863 0.137 0.000
R47 Speech disturbances, not elsewhere classified
0.863 0.137 0.000
A30-A49 Other bacterial diseases
0.862 0.138 0.000
G70-G73 Diseases of myoneural junction and muscle
0.861 0.139 0.000
H43-H45 Disorders of vitreous body and globe
0.857 0.143 0.000
N61 Inflammatory disorders of breast
0.854 0.146 0.000
F41 Other anxiety disorders
0.852 0.148 0.000
H27 Other disorders of lens
0.846 0.154 0.000
M80-M85 Disorders of bone density and structure
0.845 0.155 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.843 0.156 0.000
T66-T78 Other and unspecified effects of external causes
0.842 0.158 0.000
M79.8 Other specified soft tissue disorders
0.842 0.158 0.000
F33 Recurrent depressive disorder
0.837 0.163 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.837 0.163 0.000
C51-C58 Malignant neoplasms of female genital organs
0.833 0.167 0.000
M15-M19 Arthrosis
0.832 0.168 0.000
N83.2 Other and unspecified ovarian cysts
0.830 0.170 0.000
I44 Atrioventricular and left bundle-branch block
0.830 0.170 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.829 0.171 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.829 0.171 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.828 0.172 0.000
M86-M90 Other osteopathies
0.828 0.172 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.828 0.172 0.000
R25 Abnormal involuntary movements
0.827 0.173 0.000
H26.9 Cataract, unspecified
0.825 0.175 0.000
R21 Rash and other nonspecific skin eruption
0.824 0.176 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.823 0.177 0.000
R27 Other lack of coordination
0.823 0.177 0.000
M13.9 Arthritis, unspecified
0.822 0.178 0.000
F32 Depressive episode
0.821 0.179 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.817 0.183 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.816 0.184 0.000
S90-S99 Injuries to the ankle and foot
0.813 0.187 0.000
D10-D36 Benign neoplasms
0.813 0.187 0.000
I35.9 Aortic valve disorder, unspecified
0.812 0.188 0.000
L81 Other disorders of pigmentation
0.812 0.188 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.811 0.189 0.000
I36 Nonrheumatic tricuspid valve disorders
0.811 0.189 0.000
M79.1 Myalgia
0.811 0.189 0.000
L94 Other localised connective tissue disorders
0.810 0.190 0.000
R00.0 Tachycardia, unspecified
0.810 0.190 0.000
M06 Other rheumatoid arthritis
0.810 0.190 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.809 0.191 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.808 0.192 0.000
I69.3 Sequelae of cerebral infarction
0.808 0.192 0.000
I08 Multiple valve diseases
0.807 0.193 0.000
Chapter XXII Codes for special purposes
0.807 0.193 0.000
L03 Cellulitis
0.806 0.194 0.000
T51 Toxic effect of alcohol
0.806 0.194 0.000
R47.0 Dysphasia and aphasia
0.806 0.194 0.000
I45.5 Other specified heart block
0.803 0.197 0.000
R80 Isolated proteinuria
0.796 0.204 0.000
M72 Fibroblastic disorders
0.795 0.204 0.000
I51.7 Cardiomegaly
0.795 0.205 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.794 0.206 0.000
I37 Pulmonary valve disorders
0.793 0.207 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.793 0.207 0.000
Chapter XX External causes of morbidity and mortality
0.791 0.209 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.789 0.211 0.000
H65-H75 Diseases of middle ear and mastoid
0.789 0.211 0.000
I42.0 Dilated cardiomyopathy
0.786 0.214 0.000
I46 Cardiac arrest
0.784 0.216 0.000
N94.6 Dysmenorrhoea, unspecified
0.783 0.217 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.783 0.217 0.000
N80.0 Endometriosis of uterus
0.782 0.218 0.000
I05 Rheumatic mitral valve diseases
0.782 0.218 0.000
A49 Bacterial infection of unspecified site
0.781 0.219 0.000
A00-A09 Intestinal infectious diseases
0.780 0.219 0.000
B25-B34 Other viral diseases
0.780 0.220 0.000
F31 Bipolar affective disorder
0.779 0.221 0.000
B35-B49 Mycoses
0.779 0.221 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.776 0.224 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.775 0.225 0.000
C79 Secondary malignant neoplasm of other sites
0.775 0.225 0.000
I45.8 Other specified conduction disorders
0.775 0.225 0.000
I45.2 Bifascicular block
0.773 0.227 0.000
L93 Lupus erythematosus
0.772 0.228 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.772 0.228 0.000
H04.2 Epiphora
0.770 0.230 0.000
M40-M43 Deforming dorsopathies
0.770 0.230 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.769 0.231 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.769 0.231 0.000
S20 Superficial injury of thorax
0.769 0.231 0.000
G82 Paraplegia and tetraplegia
0.768 0.231 0.000
H90-H95 Other disorders of ear
0.767 0.233 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.766 0.234 0.000
G80 Infantile cerebral palsy
0.766 0.234 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.766 0.234 0.000
F99-F99 Unspecified mental disorder
0.765 0.234 0.000
N71 Inflammatory disease of uterus, except cervix
0.764 0.236 0.000
H25 Senile cataract
0.764 0.236 0.000
N25-N29 Other disorders of kidney and ureter
0.763 0.237 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.760 0.239 0.000
F41.9 Anxiety disorder, unspecified
0.760 0.240 0.000
N60 Benign mammary dysplasia
0.760 0.240 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.760 0.240 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.760 0.240 0.000
H35 Other retinal disorders
0.759 0.241 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.758 0.242 0.000
M81 Osteoporosis without pathological fracture
0.756 0.244 0.000
S10-S19 Injuries to the neck
0.756 0.244 0.000
L85 Other epidermal thickening
0.755 0.245 0.000
L30 Other dermatitis
0.755 0.245 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.755 0.245 0.000
N87.1 Moderate cervical dysplasia
0.755 0.245 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.754 0.246 0.000
N99-N99 Other disorders of the genitourinary system
0.754 0.246 0.000
N80.1 Endometriosis of ovary
0.753 0.247 0.000
I51.9 Heart disease, unspecified
0.752 0.248 0.000
R06 Abnormalities of breathing
0.752 0.248 0.000
H05 Disorders of orbit
0.752 0.248 0.000
N17 Acute renal failure
0.751 0.249 0.000
R26 Abnormalities of gait and mobility
0.751 0.249 0.000
H10-H13 Disorders of conjunctiva
0.750 0.250 0.000
T92 Sequelae of injuries of upper limb
0.749 0.251 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.749 0.251 0.000
I61 Intracerebral haemorrhage
0.749 0.251 0.000
H33 Retinal detachments and breaks
0.747 0.253 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.747 0.253 0.000
N87.0 Mild cervical dysplasia
0.745 0.254 0.000
F43 Reaction to severe stress, and adjustment disorders
0.745 0.255 0.000
M18 Arthrosis of first carpometacarpal joint
0.745 0.255 0.000
M19 Other arthrosis
0.745 0.255 0.000
N83.0 Follicular cyst of ovary
0.744 0.256 0.000
F80-F89 Disorders of psychological development
0.743 0.257 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.743 0.257 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.743 0.257 0.000
F30 Manic episode
0.741 0.258 0.000
I60.8 Other subarachnoid haemorrhage
0.741 0.259 0.000
M75.3 Calcific tendinitis of shoulder
0.739 0.261 0.000
H25.8 Other senile cataract
0.739 0.261 0.000
L08 Other local infections of skin and subcutaneous tissue
0.738 0.262 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.738 0.262 0.000
M46 Other inflammatory spondylopathies
0.737 0.263 0.000
N00-N08 Glomerular diseases
0.737 0.263 0.000
N18.0 End-stage renal disease
0.735 0.264 0.000
A49.0 Staphylococcal infection, unspecified
0.734 0.266 0.000
G40-G47 Episodic and paroxysmal disorders
0.734 0.266 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.733 0.267 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.732 0.268 0.000
I42.9 Cardiomyopathy, unspecified
0.732 0.268 0.000
I11 Hypertensive heart disease
0.731 0.269 0.000
T51.0 Ethanol
0.731 0.269 0.000
M11 Other crystal arthropathies
0.730 0.270 0.000
M65-M68 Disorders of synovium and tendon
0.729 0.271 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.728 0.271 0.000
I42.8 Other cardiomyopathies
0.728 0.272 0.000
L03.2 Cellulitis of face
0.728 0.272 0.000
F41.2 Mixed anxiety and depressive disorder
0.727 0.273 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.726 0.274 0.000
M75.9 Shoulder lesion, unspecified
0.726 0.274 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.725 0.275 0.000
I42.2 Other hypertrophic cardiomyopathy
0.724 0.276 0.000
G72 Other myopathies
0.724 0.276 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.724 0.276 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.724 0.276 0.000
C56 Malignant neoplasm of ovary
0.723 0.277 0.000
H44 Disorders of globe
0.723 0.277 0.000
M79.6 Pain in limb
0.722 0.278 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.720 0.280 0.000
N18.4 Chronic kidney disease, stage 4
0.718 0.281 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.718 0.282 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
G24 Dystonia
0.715 0.285 0.000
L81.9 Disorder of pigmentation, unspecified
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I30 Acute pericarditis
0.715 0.285 0.000
I15 Secondary hypertension
0.715 0.285 0.000
I13 Hypertensive heart and renal disease
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.285 0.000
H27.8 Other specified disorders of lens
0.714 0.286 0.000
I44.7 Left bundle-branch block, unspecified
0.714 0.286 0.000
L10-L14 Bullous disorders
0.714 0.286 0.000
L60-L75 Disorders of skin appendages
0.714 0.286 0.000
D34 Benign neoplasm of thyroid gland
0.713 0.287 0.000
L03.8 Cellulitis of other sites
0.713 0.287 0.000
M19.0 Primary arthrosis of other joints
0.712 0.288 0.000
M48 Other spondylopathies
0.712 0.288 0.000
H04.1 Other disorders of lachrymal gland
0.711 0.289 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
F60-F69 Disorders of adult personality and behaviour
0.710 0.290 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.709 0.291 0.000
T79-T79 Certain early complications of trauma
0.709 0.291 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.708 0.291 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.708 0.291 0.000
M76 Enthesopathies of lower limb, excluding foot
0.707 0.293 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.707 0.293 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.707 0.293 0.000
M75.5 Bursitis of shoulder
0.706 0.293 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
D17 Benign lipomatous neoplasm
0.706 0.294 0.000
S68 Traumatic amputation of wrist and hand
0.705 0.294 0.000
M05 Seropositive rheumatoid arthritis
0.705 0.295 0.000
M10 Gout
0.705 0.295 0.000
G30-G32 Other degenerative diseases of the nervous system
0.704 0.295 0.000
I08.0 Disorders of both mitral and aortic valves
0.704 0.296 0.000
H02.3 Blepharochalasis
0.704 0.296 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.704 0.296 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.704 0.296 0.000
L87 Transepidermal elimination disorders
0.704 0.296 0.000
L88 Pyoderma gangrenosum
0.704 0.296 0.000
L86 Keratoderma in diseases classified elsewhere
0.704 0.296 0.000
L83 Acanthosis nigricans
0.704 0.296 0.000
L80 Vitiligo
0.704 0.296 0.000
G83 Other paralytic syndromes
0.702 0.298 0.000
S91 Open wound of ankle and foot
0.702 0.298 0.000
R47.1 Dysarthria and anarthria
0.701 0.299 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.700 0.300 0.000
G25 Other extrapyramidal and movement disorders
0.699 0.301 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.699 0.301 0.000
I45.4 Nonspecific intraventricular block
0.699 0.301 0.000
I45.3 Trifascicular block
0.699 0.301 0.000
I45.0 Right fascicular block
0.699 0.301 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.699 0.301 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.699 0.301 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.698 0.302 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.698 0.302 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.697 0.303 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.697 0.303 0.000
L91 Hypertrophic disorders of skin
0.696 0.304 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.696 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.696 0.304 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.696 0.304 0.000
R29.4 Clicking hip
0.695 0.304 0.000
R29.3 Abnormal posture
0.695 0.304 0.000
R29.2 Abnormal reflex
0.695 0.304 0.000
R29.1 Meningismus
0.695 0.304 0.000
R29.0 Tetany
0.695 0.304 0.000
C07 Malignant neoplasm of parotid gland
0.695 0.305 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.694 0.306 0.000
I35.8 Other aortic valve disorders
0.694 0.306 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.694 0.306 0.000
L50-L54 Urticaria and erythema
0.693 0.307 0.000
H02.6 Xanthelasma of eyelid
0.693 0.307 0.000
L29 Pruritus
0.693 0.307 0.000
H27.1 Dislocation of lens
0.693 0.307 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.691 0.309 0.000
L90 Atrophic disorders of skin
0.691 0.309 0.000
I51.4 Myocarditis, unspecified
0.691 0.309 0.000
B44 Aspergillosis
0.691 0.309 0.000
S80-S89 Injuries to the knee and lower leg
0.690 0.309 0.000
F42 Obsessive-compulsive disorder
0.690 0.310 0.000
L89 Decubitus ulcer
0.690 0.310 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.690 0.310 0.000
N70 Salpingitis and oophoritis
0.690 0.310 0.000
R27.0 Ataxia, unspecified
0.690 0.310 0.000
H55-H59 Other disorders of eye and adnexa
0.690 0.310 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.690 0.310 0.000
N18.8 Other chronic renal failure
0.689 0.311 0.000
N18.2 Chronic kidney disease, stage 2
0.689 0.311 0.000
N18.1 Chronic kidney disease, stage 1
0.689 0.311 0.000
M15 Polyarthrosis
0.689 0.311 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.688 0.312 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.688 0.312 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.688 0.312 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.688 0.312 0.000
M79.9 Soft tissue disorder, unspecified
0.688 0.312 0.000
M79.5 Residual foreign body in soft tissue
0.688 0.312 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.688 0.312 0.000
M79.3 Panniculitis, unspecified
0.688 0.312 0.000
M79.2 Neuralgia and neuritis, unspecified
0.688 0.312 0.000
T78 Adverse effects, not elsewhere classified
0.688 0.312 0.000
L94.0 Localised scleroderma [morphea]
0.688 0.312 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.688 0.312 0.000
G70 Myasthenia gravis and other myoneural disorders
0.688 0.312 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.687 0.313 0.000
F32.0 Mild depressive episode
0.687 0.313 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.687 0.313 0.000
M06.9 Rheumatoid arthritis, unspecified
0.687 0.313 0.000
C53 Malignant neoplasm of cervix uteri
0.686 0.314 0.000
N86 Erosion and ectropion of cervix uteri
0.686 0.314 0.000
D00-D09 In situ neoplasms
0.686 0.314 0.000
M14 Arthropathies in other diseases classified elsewhere
0.685 0.315 0.000
M12 Other specific arthropathies
0.685 0.315 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.685 0.315 0.000
M08 Juvenile arthritis
0.685 0.315 0.000
S27 Injury of other and unspecified intrathoracic organs
0.685 0.315 0.000
H02.9 Disorder of eyelid, unspecified
0.684 0.316 0.000
F38 Other mood [affective] disorders
0.682 0.317 0.000
F34 Persistent mood [affective] disorders
0.682 0.317 0.000
F39 Unspecified mood [affective] disorder
0.682 0.317 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.682 0.318 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.682 0.318 0.000
R23 Other skin changes
0.682 0.318 0.000
F33.9 Recurrent depressive disorder, unspecified
0.682 0.318 0.000
M47 Spondylosis
0.681 0.319 0.000
N98 Complications associated with artificial fertilisation
0.681 0.319 0.000
N91 Absent, scanty and rare menstruation
0.681 0.319 0.000
N82 Fistulae involving female genital tract
0.681 0.319 0.000
N96 Habitual aborter
0.681 0.319 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.681 0.319 0.000
L05 Pilonidal cyst
0.680 0.319 0.000
T43.2 Other and unspecified antidepressants
0.679 0.321 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.678 0.322 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.678 0.322 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.678 0.322 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.678 0.322 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.678 0.322 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.678 0.322 0.000
C78.2 Secondary malignant neoplasm of pleura
0.678 0.322 0.000
H02.0 Entropion and trichiasis of eyelid
0.678 0.322 0.000
H26.8 Other specified cataract
0.677 0.323 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.677 0.323 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.676 0.324 0.000
N73.5 Female pelvic peritonitis, unspecified
0.676 0.324 0.000
N73.4 Female chronic pelvic peritonitis
0.676 0.324 0.000
N73.3 Female acute pelvic peritonitis
0.676 0.324 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.676 0.324 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.676 0.324 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.676 0.324 0.000
M71 Other bursopathies
0.676 0.324 0.000
M13.93 Arthritis, unspecified (Forearm)
0.676 0.324 0.000
G23 Other degenerative diseases of basal ganglia
0.675 0.325 0.000
G21 Secondary Parkinsonism
0.675 0.325 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.675 0.325 0.000
G22 Parkinsonism in diseases classified elsewhere
0.675 0.325 0.000
H02.5 Other disorders affecting eyelid function
0.675 0.325 0.000
H43 Disorders of vitreous body
0.675 0.325 0.000
M88 Paget's disease of bone [osteitis deformans]
0.674 0.326 0.000
M20-M25 Other joint disorders
0.674 0.326 0.000
M81.9 Osteoporosis, unspecified
0.674 0.326 0.000
N72 Inflammatory disease of cervix uteri
0.673 0.327 0.000
I05.2 Mitral stenosis with insufficiency
0.673 0.327 0.000
F25 Schizoaffective disorders
0.673 0.327 0.000
T68 Hypothermia
0.672 0.328 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.670 0.329 0.000
H35.3 Degeneration of macula and posterior pole
0.670 0.330 0.000
L28 Lichen simplex chronicus and prurigo
0.670 0.330 0.000
M07 Psoriatic and enteropathic arthropathies
0.670 0.330 0.000
L30.9 Dermatitis, unspecified
0.670 0.330 0.000
S22.0 Fracture of thoracic vertebra
0.668 0.332 0.000
M84 Disorders of continuity of bone
0.668 0.332 0.000
R81 Glycosuria
0.668 0.332 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.668 0.332 0.000
N19 Unspecified renal failure
0.667 0.333 0.000
S70-S79 Injuries to the hip and thigh
0.667 0.333 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.667 0.333 0.000
D18 Haemangioma and lymphangioma, any site
0.667 0.333 0.000
H71 Cholesteatoma of middle ear
0.666 0.333 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.666 0.334 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.665 0.335 0.000
I42.6 Alcoholic cardiomyopathy
0.665 0.335 0.000
I42.5 Other restrictive cardiomyopathy
0.665 0.335 0.000
I42.4 Endocardial fibroelastosis
0.665 0.335 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.665 0.335 0.000
S64 Injury of nerves at wrist and hand level
0.665 0.335 0.000
G95 Other diseases of spinal cord
0.665 0.335 0.000
N83.1 Corpus luteum cyst
0.664 0.336 0.000
N18.5 Chronic kidney disease, stage 5
0.664 0.336 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.663 0.337 0.000
F20 Schizophrenia
0.663 0.337 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.663 0.337 0.000
G81.1 Spastic hemiplegia
0.662 0.338 0.000
G81.0 Flaccid hemiplegia
0.662 0.338 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.662 0.338 0.000
G03 Meningitis due to other and unspecified causes
0.662 0.338 0.000
I07 Rheumatic tricuspid valve diseases
0.661 0.338 0.000
T90 Sequelae of injuries of head
0.661 0.339 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.661 0.339 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.660 0.340 0.000
L40-L45 Papulosquamous disorders
0.659 0.340 0.000
N97 Female infertility
0.659 0.341 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.659 0.341 0.000
I44.3 Other and unspecified atrioventricular block
0.659 0.341 0.000
I09 Other rheumatic heart diseases
0.659 0.341 0.000
I06 Rheumatic aortic valve diseases
0.659 0.341 0.000
H92 Otalgia and effusion of ear
0.659 0.341 0.000
F41.1 Generalised anxiety disorder
0.659 0.341 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.659 0.341 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.658 0.342 0.000
T91 Sequelae of injuries of neck and trunk
0.658 0.342 0.000
N80.6 Endometriosis in cutaneous scar
0.658 0.342 0.000
N80.5 Endometriosis of intestine
0.658 0.342 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.658 0.342 0.000
L04 Acute lymphadenitis
0.657 0.342 0.000
L01 Impetigo
0.657 0.342 0.000
L00 Staphylococcal scalded skin syndrome
0.657 0.342 0.000
H65 Nonsuppurative otitis media
0.656 0.344 0.000
D23 Other benign neoplasms of skin
0.656 0.344 0.000
I33 Acute and subacute endocarditis
0.655 0.344 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.655 0.345 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.655 0.345 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.655 0.345 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.655 0.345 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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