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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117631583
log Bayes Factor = 15.1608
Chromosome 7   position 78,667,335  (GRCh37) Explore rs117631583 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
N40-N51 Diseases of male genital organs
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
M20-M25 Other joint disorders
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.985 0.015 0.000
I50 Heart failure
0.984 0.016 0.000
I51 Complications and ill-defined descriptions of heart disease
0.981 0.019 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
N39 Other disorders of urinary system
0.975 0.025 0.000
O00-O08 Pregnancy with abortive outcome
0.965 0.035 0.000
N39.0 Urinary tract infection, site not specified
0.964 0.036 0.000
I50.0 Congestive heart failure
0.962 0.038 0.000
N41 Inflammatory diseases of prostate
0.961 0.039 0.000
M23 Internal derangement of knee
0.959 0.041 0.000
M05-M14 Inflammatory polyarthropathies
0.959 0.041 0.000
N32 Other disorders of bladder
0.958 0.042 0.000
I51.7 Cardiomegaly
0.955 0.045 0.000
I73 Other peripheral vascular diseases
0.953 0.047 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.941 0.059 0.000
O60-O75 Complications of labour and delivery
0.941 0.059 0.000
I05-I09 Chronic rheumatic heart diseases
0.938 0.062 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.937 0.063 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.936 0.064 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.915 0.085 0.000
O03 Spontaneous abortion
0.910 0.090 0.000
I44 Atrioventricular and left bundle-branch block
0.910 0.090 0.000
M25 Other joint disorders, not elsewhere classified
0.906 0.094 0.000
I49 Other cardiac arrhythmias
0.902 0.098 0.000
F41 Other anxiety disorders
0.902 0.098 0.000
N32.8 Other specified disorders of bladder
0.901 0.099 0.000
N41.1 Chronic prostatitis
0.899 0.101 0.000
N00-N08 Glomerular diseases
0.895 0.105 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.894 0.106 0.000
N42 Other disorders of prostate
0.893 0.107 0.000
N36 Other disorders of urethra
0.892 0.108 0.000
Chapter VIII Diseases of the ear and mastoid process
0.891 0.109 0.000
O02 Other abnormal products of conception
0.890 0.110 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.890 0.110 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.887 0.113 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.886 0.114 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.885 0.115 0.000
I08 Multiple valve diseases
0.884 0.116 0.000
I51.9 Heart disease, unspecified
0.883 0.117 0.000
M06 Other rheumatoid arthritis
0.880 0.120 0.000
M45-M49 Spondylopathies
0.880 0.120 0.000
I31 Other diseases of pericardium
0.879 0.121 0.000
M35 Other systemic involvement of connective tissue
0.878 0.122 0.000
I73.9 Peripheral vascular disease, unspecified
0.877 0.123 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.876 0.124 0.000
Chapter VI Diseases of the nervous system
0.872 0.128 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.871 0.129 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.871 0.129 0.000
I45 Other conduction disorders
0.863 0.137 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.860 0.140 0.000
I10-I15 Hypertensive diseases
0.858 0.142 0.000
I77 Other disorders of arteries and arterioles
0.856 0.144 0.000
I50.9 Heart failure, unspecified
0.855 0.145 0.000
N39.9 Disorder of urinary system, unspecified
0.847 0.153 0.000
E00-E07 Disorders of thyroid gland
0.846 0.154 0.000
F41.9 Anxiety disorder, unspecified
0.845 0.155 0.000
I44.7 Left bundle-branch block, unspecified
0.843 0.157 0.000
I46 Cardiac arrest
0.841 0.158 0.000
M25.5 Pain in joint
0.841 0.159 0.000
I60-I69 Cerebrovascular diseases
0.838 0.162 0.000
N32.9 Bladder disorder, unspecified
0.836 0.164 0.000
N41.0 Acute prostatitis
0.835 0.165 0.000
I71 Aortic aneurysm and dissection
0.833 0.167 0.000
M40-M43 Deforming dorsopathies
0.832 0.168 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.831 0.169 0.000
G90-G99 Other disorders of the nervous system
0.830 0.170 0.000
I35 Nonrheumatic aortic valve disorders
0.827 0.173 0.000
O20 Haemorrhage in early pregnancy
0.827 0.173 0.000
N60-N64 Disorders of breast
0.827 0.173 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.827 0.173 0.000
M06.9 Rheumatoid arthritis, unspecified
0.825 0.175 0.000
N48 Other disorders of penis
0.824 0.176 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
M05 Seropositive rheumatoid arthritis
0.823 0.177 0.000
N99-N99 Other disorders of the genitourinary system
0.822 0.178 0.000
O02.1 Missed abortion
0.821 0.179 0.000
W00-W19 Falls
0.817 0.183 0.000
O03.4 Incomplete, without complication
0.817 0.183 0.000
N36.8 Other specified disorders of urethra
0.816 0.184 0.000
M35.3 Polymyalgia rheumatica
0.814 0.186 0.000
I34 Nonrheumatic mitral valve disorders
0.814 0.186 0.000
I47 Paroxysmal tachycardia
0.813 0.187 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.813 0.187 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.812 0.188 0.000
I49.9 Cardiac arrhythmia, unspecified
0.809 0.191 0.000
I38 Endocarditis, valve unspecified
0.808 0.192 0.000
Y86 Sequelae of other accidents
0.806 0.194 0.000
F01 Vascular dementia
0.805 0.195 0.000
N10-N16 Renal tubulo-interstitial diseases
0.804 0.196 0.000
O80-O84 Delivery
0.804 0.196 0.000
N43 Hydrocele and spermatocele
0.804 0.196 0.000
Chapter VII Diseases of the eye and adnexa
0.804 0.196 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.803 0.197 0.000
O03.9 Complete or unspecified, without complication
0.800 0.199 0.000
M25.56 Pain in joint (Lower leg)
0.800 0.200 0.000
I73.8 Other specified peripheral vascular diseases
0.795 0.205 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.794 0.206 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.792 0.208 0.000
S80-S89 Injuries to the knee and lower leg
0.792 0.208 0.000
I31.3 Pericardial effusion (noninflammatory)
0.791 0.209 0.000
M48 Other spondylopathies
0.786 0.214 0.000
I95 Hypotension
0.785 0.215 0.000
I78 Diseases of capillaries
0.784 0.216 0.000
F03 Unspecified dementia
0.784 0.216 0.000
M23.8 Other internal derangements of knee
0.783 0.217 0.000
M11 Other crystal arthropathies
0.782 0.218 0.000
I73.0 Raynaud's syndrome
0.781 0.219 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.781 0.219 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.779 0.221 0.000
N42.8 Other specified disorders of prostate
0.779 0.221 0.000
M10 Gout
0.778 0.222 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.778 0.222 0.000
G91 Hydrocephalus
0.770 0.230 0.000
N45 Orchitis and epididymitis
0.768 0.232 0.000
M21 Other acquired deformities of limbs
0.768 0.232 0.000
H65-H75 Diseases of middle ear and mastoid
0.767 0.233 0.000
N02 Recurrent and persistent haematuria
0.766 0.234 0.000
E50-E64 Other nutritional deficiencies
0.766 0.234 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.766 0.234 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.766 0.234 0.000
I44.6 Other and unspecified fascicular block
0.766 0.234 0.000
N30 Cystitis
0.765 0.235 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.763 0.237 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.760 0.240 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.759 0.241 0.000
I72 Other aneurysm
0.759 0.241 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.759 0.241 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.758 0.242 0.000
O73 Retained placenta and membranes, without haemorrhage
0.758 0.242 0.000
Chapter XXII Codes for special purposes
0.757 0.243 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.755 0.245 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.751 0.249 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.751 0.249 0.000
I74 Arterial embolism and thrombosis
0.750 0.250 0.000
N35 Urethral stricture
0.750 0.250 0.000
N32.1 Vesicointestinal fistula
0.750 0.250 0.000
M23.5 Chronic instability of knee
0.749 0.251 0.000
I70 Atherosclerosis
0.748 0.252 0.000
O66 Other obstructed labour
0.747 0.253 0.000
N25-N29 Other disorders of kidney and ureter
0.747 0.253 0.000
V80-V89 Other land transport accidents
0.746 0.254 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.746 0.254 0.000
I46.0 Cardiac arrest with successful resuscitation
0.743 0.257 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.742 0.258 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.736 0.264 0.000
I95.1 Orthostatic hypotension
0.735 0.265 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.734 0.266 0.000
M25.4 Effusion of joint
0.732 0.268 0.000
I44.0 Atrioventricular block, first degree
0.731 0.269 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.731 0.269 0.000
N32.0 Bladder-neck obstruction
0.731 0.269 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.731 0.269 0.000
O72 Postpartum haemorrhage
0.730 0.269 0.000
I45.1 Other and unspecified right bundle-branch block
0.730 0.270 0.000
M25.50 Pain in joint (Multiple sites)
0.730 0.270 0.000
M24 Other specific joint derangements
0.729 0.271 0.000
O63 Long labour
0.729 0.271 0.000
M86-M90 Other osteopathies
0.728 0.272 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.728 0.272 0.000
I49.3 Ventricular premature depolarisation
0.727 0.273 0.000
I12 Hypertensive renal disease
0.727 0.273 0.000
M80-M85 Disorders of bone density and structure
0.727 0.273 0.000
H90-H95 Other disorders of ear
0.726 0.274 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.725 0.275 0.000
E05.9 Thyrotoxicosis, unspecified
0.723 0.277 0.000
V10-V19 Pedal cyclist injured in transport accident
0.723 0.277 0.000
M23.4 Loose body in knee
0.722 0.278 0.000
I07 Rheumatic tricuspid valve diseases
0.722 0.278 0.000
I67 Other cerebrovascular diseases
0.722 0.278 0.000
F43 Reaction to severe stress, and adjustment disorders
0.721 0.279 0.000
I42 Cardiomyopathy
0.721 0.279 0.000
F60-F69 Disorders of adult personality and behaviour
0.719 0.281 0.000
M48.0 Spinal stenosis
0.718 0.282 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N42.0 Calculus of prostate
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.283 0.000
N34 Urethritis and urethral syndrome
0.716 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.283 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.716 0.284 0.000
I77.1 Stricture of artery
0.716 0.284 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.715 0.285 0.000
N46 Male infertility
0.715 0.285 0.000
N44 Torsion of testis
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.713 0.287 0.000
N17-N19 Renal failure
0.713 0.287 0.000
Y40 Systemic antibiotics
0.712 0.288 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.712 0.288 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.711 0.289 0.000
F01.9 Vascular dementia, unspecified
0.711 0.289 0.000
F40 Phobic anxiety disorders
0.710 0.290 0.000
H53-H54 Visual disturbances and blindness
0.710 0.290 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.707 0.293 0.000
M34 Systemic sclerosis
0.707 0.293 0.000
M33 Dermatopolymyositis
0.707 0.293 0.000
M32 Systemic lupus erythematosus
0.707 0.293 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
F99-F99 Unspecified mental disorder
0.706 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
F80-F89 Disorders of psychological development
0.706 0.294 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.705 0.295 0.000
M41 Scoliosis
0.703 0.297 0.000
I51.6 Cardiovascular disease, unspecified
0.703 0.297 0.000
I51.5 Myocardial degeneration
0.703 0.297 0.000
I51.4 Myocarditis, unspecified
0.703 0.297 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.703 0.297 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.703 0.297 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.703 0.297 0.000
I51.0 Cardiac septal defect, acquired
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
X50-X57 Overexertion, travel and privation
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
W50-W64 Exposure to animate mechanical forces
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V40-V49 Car occupant injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V20-V29 Motorcycle rider injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
N03 Chronic nephritic syndrome
0.701 0.299 0.000
O62 Abnormalities of forces of labour
0.700 0.300 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.700 0.300 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.700 0.300 0.000
N39.2 Orthostatic proteinuria, unspecified
0.699 0.301 0.000
N39.1 Persistent proteinuria, unspecified
0.699 0.301 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.699 0.301 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.698 0.302 0.000
N40 Hyperplasia of prostate
0.698 0.302 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.697 0.303 0.000
S20-S29 Injuries to the thorax
0.695 0.305 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.695 0.305 0.000
I33 Acute and subacute endocarditis
0.695 0.305 0.000
M49 Spondylopathies in diseases classified elsewhere
0.695 0.305 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.693 0.307 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.692 0.308 0.000
O07 Failed attempted abortion
0.692 0.308 0.000
O06 Unspecified abortion
0.692 0.308 0.000
O05 Other abortion
0.692 0.308 0.000
O01 Hydatidiform mole
0.692 0.308 0.000
O00 Ectopic pregnancy
0.692 0.308 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.691 0.309 0.000
G91.9 Hydrocephalus, unspecified
0.691 0.309 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.691 0.309 0.000
M22 Disorders of patella
0.689 0.311 0.000
N41.8 Other inflammatory diseases of prostate
0.689 0.311 0.000
N41.3 Prostatocystitis
0.689 0.311 0.000
N41.2 Abscess of prostate
0.689 0.311 0.000
M23.3 Other meniscus derangements
0.689 0.311 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.689 0.311 0.000
M23.9 Internal derangement of knee, unspecified
0.688 0.312 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.688 0.312 0.000
M23.1 Discoid meniscus (congenital)
0.688 0.312 0.000
M23.0 Cystic meniscus
0.688 0.312 0.000
M14 Arthropathies in other diseases classified elsewhere
0.687 0.313 0.000
M12 Other specific arthropathies
0.687 0.313 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.687 0.313 0.000
M08 Juvenile arthritis
0.687 0.313 0.000
M07 Psoriatic and enteropathic arthropathies
0.687 0.313 0.000
W19 Unspecified fall
0.687 0.313 0.000
N48.4 Impotence of organic origin
0.687 0.313 0.000
N32.4 Rupture of bladder, nontraumatic
0.686 0.313 0.000
N32.2 Vesical fistula, not elsewhere classified
0.686 0.313 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.686 0.314 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.686 0.314 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.685 0.315 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.685 0.315 0.000
M70-M79 Other soft tissue disorders
0.684 0.316 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.683 0.316 0.000
Chapter I Certain infectious and parasitic diseases
0.683 0.317 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.683 0.317 0.000
O20.0 Threatened abortion
0.680 0.320 0.000
F00 Dementia in Alzheimer's disease
0.679 0.321 0.000
G70-G73 Diseases of myoneural junction and muscle
0.679 0.321 0.000
M65-M68 Disorders of synovium and tendon
0.678 0.321 0.000
T66-T78 Other and unspecified effects of external causes
0.678 0.322 0.000
N39.8 Other specified disorders of urinary system
0.678 0.322 0.000
Y52 Agents primarily affecting the cardiovascular system
0.677 0.322 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.677 0.322 0.000
H60-H62 Diseases of external ear
0.675 0.324 0.000
F48 Other neurotic disorders
0.675 0.325 0.000
F44 Dissociative [conversion] disorders
0.675 0.325 0.000
F42 Obsessive-compulsive disorder
0.675 0.325 0.000
O74 Complications of anaesthesia during labour and delivery
0.674 0.325 0.000
O71 Other obstetric trauma
0.674 0.325 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.674 0.325 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.674 0.325 0.000
O61 Failed induction of labour
0.674 0.325 0.000
O60 Preterm delivery
0.674 0.325 0.000
N02.9 Unspecified
0.674 0.326 0.000
M45 Ankylosing spondylitis
0.674 0.326 0.000
E55 Vitamin D deficiency
0.674 0.326 0.000
Y85 Sequelae of transport accidents
0.673 0.327 0.000
I35.1 Aortic (valve) insufficiency
0.673 0.327 0.000
I09 Other rheumatic heart diseases
0.673 0.327 0.000
I06 Rheumatic aortic valve diseases
0.673 0.327 0.000
I05 Rheumatic mitral valve diseases
0.673 0.327 0.000
N62 Hypertrophy of breast
0.672 0.328 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.672 0.328 0.000
W20-W49 Exposure to inanimate mechanical forces
0.671 0.328 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.671 0.329 0.000
F02 Dementia in other diseases classified elsewhere
0.671 0.329 0.000
F09 Unspecified organic or symptomatic mental disorder
0.671 0.329 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.671 0.329 0.000
H10-H13 Disorders of conjunctiva
0.671 0.329 0.000
F25 Schizoaffective disorders
0.670 0.330 0.000
F41.2 Mixed anxiety and depressive disorder
0.670 0.330 0.000
H73 Other disorders of tympanic membrane
0.669 0.331 0.000
N42.9 Disorder of prostate, unspecified
0.669 0.331 0.000
M25.8 Other specified joint disorders
0.669 0.331 0.000
I10 Essential (primary) hypertension
0.669 0.331 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.668 0.332 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.668 0.332 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.668 0.332 0.000
G20-G26 Extrapyramidal and movement disorders
0.666 0.334 0.000
N43.3 Hydrocele, unspecified
0.665 0.335 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.665 0.335 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.665 0.335 0.000
I49.0 Ventricular fibrillation and flutter
0.664 0.336 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.664 0.336 0.000
E06 Thyroiditis
0.661 0.339 0.000
H53 Visual disturbances
0.661 0.339 0.000
I60 Subarachnoid haemorrhage
0.660 0.340 0.000
H55-H59 Other disorders of eye and adnexa
0.659 0.341 0.000
O42 Premature rupture of membranes
0.659 0.341 0.000
I50.1 Left ventricular failure
0.658 0.342 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.658 0.342 0.000
O75.8 Other specified complications of labour and delivery
0.658 0.342 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.656 0.344 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.656 0.344 0.000
I45.5 Other specified heart block
0.656 0.344 0.000
E04 Other non-toxic goitre
0.655 0.345 0.000
M11.2 Other chondrocalcinosis
0.655 0.345 0.000
Q50-Q56 Congenital malformations of genital organs
0.655 0.345 0.000
E07 Other disorders of thyroid
0.653 0.347 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.652 0.347 0.000
O03.7 Complete or unspecified, complicated by embolism
0.652 0.347 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.652 0.347 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.652 0.347 0.000
O03.3 Incomplete, with other and unspecified complications
0.652 0.347 0.000
O03.2 Incomplete, complicated by embolism
0.652 0.347 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.652 0.347 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.652 0.347 0.000
S50-S59 Injuries to the elbow and forearm
0.652 0.348 0.000
I44.5 Left posterior fascicular block
0.652 0.348 0.000
I44.4 Left anterior fascicular block
0.652 0.348 0.000
I44.3 Other and unspecified atrioventricular block
0.652 0.348 0.000
I49.8 Other specified cardiac arrhythmias
0.652 0.348 0.000
I45.6 Preexcitation syndrome
0.651 0.349 0.000
G91.1 Obstructive hydrocephalus
0.651 0.349 0.000
M25.9 Joint disorder, unspecified
0.650 0.350 0.000
M25.3 Other instability of joint
0.650 0.350 0.000
M25.2 Flail joint
0.650 0.350 0.000
M25.1 Fistula of joint
0.650 0.350 0.000
M25.0 Haemarthrosis
0.650 0.350 0.000
M10.9 Gout, unspecified
0.649 0.351 0.000
S81 Open wound of lower leg
0.647 0.353 0.000
I49.4 Other and unspecified premature depolarisation
0.647 0.353 0.000
I49.2 Junctional premature depolarisation
0.647 0.353 0.000
I49.1 Atrial premature depolarisation
0.647 0.353 0.000
G93 Other disorders of brain
0.647 0.353 0.000
F41.8 Other specified anxiety disorders
0.647 0.353 0.000
F41.3 Other mixed anxiety disorders
0.647 0.353 0.000
F41.1 Generalised anxiety disorder
0.647 0.353 0.000
I34.1 Mitral (valve) prolapse
0.646 0.354 0.000
H92 Otalgia and effusion of ear
0.645 0.355 0.000
N63 Unspecified lump in breast
0.643 0.357 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.642 0.358 0.000
O82 Single delivery by Caesarean section
0.642 0.358 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.641 0.358 0.000
N06 Isolated proteinuria with specified morphological lesion
0.641 0.358 0.000
N05 Unspecified nephritic syndrome
0.641 0.358 0.000
N04 Nephrotic syndrome
0.641 0.358 0.000
N01 Rapidly progressive nephritic syndrome
0.641 0.358 0.000
N00 Acute nephritic syndrome
0.641 0.358 0.000
T33-T35 Frostbite
0.641 0.359 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.641 0.359 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.641 0.359 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.641 0.359 0.000
T00-T07 Injuries involving multiple body regions
0.641 0.359 0.000
S10-S19 Injuries to the neck
0.641 0.359 0.000
N42.3 Dysplasia of prostate
0.640 0.360 0.000
N42.2 Atrophy of prostate
0.640 0.360 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.640 0.360 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.640 0.360 0.000
N36.9 Urethral disorder, unspecified
0.640 0.360 0.000
N36.3 Prolapsed urethral mucosa
0.640 0.360 0.000
N36.2 Urethral caruncle
0.640 0.360 0.000
N36.1 Urethral diverticulum
0.640 0.360 0.000
N36.0 Urethral fistula
0.640 0.360 0.000
I47.2 Ventricular tachycardia
0.640 0.360 0.000
N48.0 Leukoplakia of penis
0.639 0.361 0.000
O02.9 Abnormal product of conception, unspecified
0.638 0.361 0.000
O02.8 Other specified abnormal products of conception
0.638 0.361 0.000
E40-E46 Malnutrition
0.638 0.362 0.000
T79-T79 Certain early complications of trauma
0.637 0.363 0.000
N30.8 Other cystitis
0.637 0.363 0.000
O29 Complications of anaesthesia during pregnancy
0.636 0.364 0.000
O28 Abnormal findings on antenatal screening of mother
0.636 0.364 0.000
O24 Diabetes mellitus in pregnancy
0.636 0.364 0.000
O23 Infections of genito-urinary tract in pregnancy
0.636 0.364 0.000
O22 Venous complications in pregnancy
0.636 0.364 0.000
O21 Excessive vomiting in pregnancy
0.636 0.364 0.000
O25 Malnutrition in pregnancy
0.636 0.364 0.000
I47.1 Supraventricular tachycardia
0.635 0.365 0.000
Y89 Sequelae of other external causes
0.635 0.365 0.000
Y88 Sequelae of surgical and medical care as external cause
0.635 0.365 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.635 0.365 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.635 0.365 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.635 0.365 0.000
F45 Somatoform disorders
0.635 0.365 0.000
I78.1 Naevus, nonneoplastic
0.635 0.365 0.000
H66 Suppurative and unspecified otitis media
0.634 0.366 0.000
I08.9 Multiple valve disease, unspecified
0.634 0.366 0.000
I08.8 Other multiple valve diseases
0.634 0.366 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.634 0.366 0.000
F06.7 Mild cognitive disorder
0.634 0.366 0.000
N48.2 Other inflammatory disorders of penis
0.633 0.367 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.633 0.367 0.000
I31.9 Disease of pericardium, unspecified
0.632 0.367 0.000
M06.8 Other specified rheumatoid arthritis
0.631 0.369 0.000
M06.4 Inflammatory polyarthropathy
0.631 0.369 0.000
M06.3 Rheumatoid nodule
0.631 0.369 0.000
M06.2 Rheumatoid bursitis
0.631 0.369 0.000
M06.1 Adult-onset Still's disease
0.631 0.369 0.000
I34.0 Mitral (valve) insufficiency
0.631 0.369 0.000
I31.8 Other specified diseases of pericardium
0.630 0.370 0.000
I31.2 Haemopericardium, not elsewhere classified
0.630 0.370 0.000
I31.1 Chronic constrictive pericarditis
0.630 0.370 0.000
I31.0 Chronic adhesive pericarditis
0.630 0.370 0.000
M25.51 Pain in joint (Shoulder region)
0.630 0.370 0.000
O43 Placental disorders
0.629 0.371 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.629 0.371 0.000
M35.8 Other specified systemic involvement of connective tissue
0.629 0.371 0.000
M35.7 Hypermobility syndrome
0.629 0.371 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.629 0.371 0.000
M35.5 Multifocal fibrosclerosis
0.629 0.371 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.629 0.371 0.000
M35.2 Behcet's disease
0.629 0.371 0.000
M35.1 Other overlap syndromes
0.629 0.371 0.000
G30-G32 Other degenerative diseases of the nervous system
0.629 0.371 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.628 0.372 0.000
I99 Other and unspecified disorders of circulatory system
0.628 0.372 0.000
Y45.1 Salicylates
0.628 0.372 0.000
M48.02 Spinal stenosis (Cervical region)
0.627 0.373 0.000
M06.0 Seronegative rheumatoid arthritis
0.627 0.373 0.000
O73.0 Retained placenta, without haemorrhage
0.627 0.373 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.627 0.373 0.000
N42.1 Congestion and haemorrhage of prostate
0.625 0.375 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.625 0.375 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.625 0.375 0.000
S40-S49 Injuries to the shoulder and upper arm
0.625 0.375 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.624 0.375 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.624 0.375 0.000
Y59 Other and unspecified vaccines and biological substances
0.624 0.376 0.000
Y58 Bacterial vaccines
0.624 0.376 0.000
Y57 Other and unspecified drugs and medicaments
0.624 0.376 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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