TreeWAS – Variant ID: rs2854050

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
J45 Asthma	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
# Top node	0.999	0.001	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.998	0.002	0.000
Chapter II Neoplasms	0.997	0.003	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.995	0.005	0.000
C15-C26 Malignant neoplasms of digestive organs	0.991	0.009	0.000
Chapter V Mental and behavioural disorders	0.987	0.013	0.000
D00-D09 In situ neoplasms	0.984	0.016	0.000
I30-I52 Other forms of heart disease	0.979	0.021	0.000
I42 Cardiomyopathy	0.976	0.024	0.000
E03 Other hypothyroidism	0.976	0.024	0.000
I50 Heart failure	0.974	0.026	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.973	0.027	0.000
Chapter IX Diseases of the circulatory system	0.972	0.028	0.000
J20-J22 Other acute lower respiratory infections	0.969	0.031	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.965	0.035	0.000
J43 Emphysema	0.965	0.035	0.000
C18 Malignant neoplasm of colon	0.964	0.036	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.963	0.037	0.000
E00-E07 Disorders of thyroid gland	0.962	0.038	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.958	0.042	0.000
C21 Malignant neoplasm of anus and anal canal	0.957	0.043	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.956	0.044	0.000
M06.3 Rheumatoid nodule	0.955	0.045	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.955	0.045	0.000
I50.1 Left ventricular failure	0.954	0.046	0.000
F30-F39 Mood [affective] disorders	0.951	0.049	0.000
C71 Malignant neoplasm of brain	0.951	0.049	0.000
F10.1 Harmful use	0.949	0.051	0.000
I50.0 Congestive heart failure	0.947	0.053	0.000
J22 Unspecified acute lower respiratory infection	0.946	0.054	0.000
J43.9 Emphysema, unspecified	0.945	0.055	0.000
F10.0 Acute intoxication	0.940	0.060	0.000
I47 Paroxysmal tachycardia	0.939	0.061	0.000
M06.0 Seronegative rheumatoid arthritis	0.932	0.068	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.930	0.070	0.000
I42.0 Dilated cardiomyopathy	0.929	0.071	0.000
C18.6 Descending colon	0.929	0.071	0.000
F31 Bipolar affective disorder	0.927	0.073	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.914	0.086	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.912	0.088	0.000
I47.2 Ventricular tachycardia	0.904	0.096	0.000
I05-I09 Chronic rheumatic heart diseases	0.903	0.097	0.000
I42.9 Cardiomyopathy, unspecified	0.900	0.100	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.895	0.105	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.894	0.106	0.000
C71.9 Brain, unspecified	0.891	0.109	0.000
J95-J99 Other diseases of the respiratory system	0.885	0.115	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.884	0.116	0.000
C21.1 Anal canal	0.883	0.117	0.000
J84 Other interstitial pulmonary diseases	0.880	0.120	0.000
C18.3 Hepatic flexure	0.879	0.121	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.878	0.122	0.000
D07.1 Vulva	0.875	0.125	0.000
C21.0 Anus, unspecified	0.871	0.129	0.000
Chapter VIII Diseases of the ear and mastoid process	0.870	0.130	0.000
I08 Multiple valve diseases	0.868	0.132	0.000
M06.34 Rheumatoid nodule (Hand)	0.866	0.134	0.000
M06.4 Inflammatory polyarthropathy	0.865	0.135	0.000
I46 Cardiac arrest	0.864	0.136	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.864	0.136	0.000
J46 Status asthmaticus	0.860	0.140	0.000
D07.4 Penis	0.859	0.141	0.000
M20-M25 Other joint disorders	0.858	0.142	0.000
C16 Malignant neoplasm of stomach	0.856	0.144	0.000
C71.0 Cerebrum, except lobes and ventricles	0.854	0.146	0.000
J40 Bronchitis, not specified as acute or chronic	0.852	0.147	0.000
D06 Carcinoma in situ of cervix uteri	0.851	0.149	0.000
D10-D36 Benign neoplasms	0.838	0.162	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.838	0.162	0.000
D27 Benign neoplasm of ovary	0.833	0.167	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.833	0.167	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.828	0.172	0.000
M40-M43 Deforming dorsopathies	0.827	0.173	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.823	0.177	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.821	0.179	0.000
C07 Malignant neoplasm of parotid gland	0.820	0.180	0.000
I08.0 Disorders of both mitral and aortic valves	0.815	0.185	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.813	0.187	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.812	0.188	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.811	0.189	0.000
I51 Complications and ill-defined descriptions of heart disease	0.811	0.189	0.000
E04 Other non-toxic goitre	0.810	0.190	0.000
I46.0 Cardiac arrest with successful resuscitation	0.809	0.191	0.000
D09 Carcinoma in situ of other and unspecified sites	0.807	0.193	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.805	0.195	0.000
C71.1 Frontal lobe	0.804	0.196	0.000
I42.6 Alcoholic cardiomyopathy	0.802	0.198	0.000
I31 Other diseases of pericardium	0.800	0.200	0.000
M05.8 Other seropositive rheumatoid arthritis	0.799	0.201	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.798	0.202	0.000
D12.8 Rectum	0.797	0.203	0.000
I42.2 Other hypertrophic cardiomyopathy	0.795	0.205	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.795	0.205	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.795	0.205	0.000
J09-J18 Influenza and pneumonia	0.794	0.206	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.794	0.206	0.000
F31.9 Bipolar affective disorder, unspecified	0.793	0.207	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.791	0.209	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.789	0.211	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.788	0.212	0.000
C32 Malignant neoplasm of larynx	0.786	0.214	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.774	0.226	0.000
M91-M94 Chondropathies	0.772	0.227	0.000
F32 Depressive episode	0.769	0.231	0.000
M00-M03 Infectious arthropathies	0.767	0.233	0.000
S50-S59 Injuries to the elbow and forearm	0.767	0.233	0.000
C17 Malignant neoplasm of small intestine	0.765	0.235	0.000
D12.5 Sigmoid colon	0.762	0.238	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.762	0.238	0.000
C18.8 Overlapping lesion of colon	0.761	0.239	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.760	0.240	0.000
M11 Other crystal arthropathies	0.760	0.240	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.756	0.244	0.000
F45 Somatoform disorders	0.753	0.247	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.753	0.247	0.000
C23 Malignant neoplasm of gallbladder	0.752	0.248	0.000
I36 Nonrheumatic tricuspid valve disorders	0.752	0.248	0.000
F99-F99 Unspecified mental disorder	0.751	0.249	0.000
I42.8 Other cardiomyopathies	0.750	0.250	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.748	0.252	0.000
C69 Malignant neoplasm of eye and adnexa	0.747	0.253	0.000
C18.5 Splenic flexure	0.743	0.257	0.000
M35 Other systemic involvement of connective tissue	0.743	0.257	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.743	0.257	0.000
H90-H95 Other disorders of ear	0.742	0.258	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.739	0.261	0.000
S20-S29 Injuries to the thorax	0.737	0.263	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.736	0.264	0.000
H80-H83 Diseases of inner ear	0.734	0.266	0.000
K90 Intestinal malabsorption	0.000	0.267	0.732
M60-M63 Disorders of muscles	0.732	0.268	0.000
E06 Thyroiditis	0.732	0.268	0.000
J21 Acute bronchiolitis	0.732	0.268	0.000
I51.7 Cardiomegaly	0.732	0.268	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.727	0.273	0.000
C05 Malignant neoplasm of palate	0.727	0.273	0.000
M22 Disorders of patella	0.727	0.273	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.726	0.274	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.726	0.274	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.725	0.275	0.000
F41 Other anxiety disorders	0.722	0.278	0.000
C32.0 Glottis	0.721	0.279	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.721	0.279	0.000
M31 Other necrotising vasculopathies	0.721	0.279	0.000
C34 Malignant neoplasm of bronchus and lung	0.720	0.280	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.719	0.281	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.717	0.283	0.000
D03 Melanoma in situ	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.717	0.283	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.717	0.283	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.1 Rheumatoid lung disease	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283	0.000
J45.8 Mixed asthma	0.717	0.283	0.000
J45.1 Nonallergic asthma	0.717	0.283	0.000
D06.9 Cervix, unspecified	0.716	0.284	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.715	0.285	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.714	0.286	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.713	0.287	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.710	0.290	0.000
C18.1 Appendix	0.710	0.290	0.000
S51 Open wound of forearm	0.709	0.291	0.000
S90-S99 Injuries to the ankle and foot	0.708	0.292	0.000
I09 Other rheumatic heart diseases	0.708	0.292	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.707	0.293	0.000
F70-F79 Mental retardation	0.707	0.293	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.706	0.294	0.000
J99.0 Rheumatoid lung disease	0.706	0.294	0.000
F48 Other neurotic disorders	0.705	0.295	0.000
I52 Other heart disorders in diseases classified elsewhere	0.702	0.298	0.000
I48 Atrial fibrillation and flutter	0.702	0.298	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.702	0.298	0.000
I41 Myocarditis in diseases classified elsewhere	0.702	0.298	0.000
I40 Acute myocarditis	0.702	0.298	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.702	0.298	0.000
I32 Pericarditis in diseases classified elsewhere	0.702	0.298	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.700	0.300	0.000
I42.5 Other restrictive cardiomyopathy	0.700	0.300	0.000
I42.4 Endocardial fibroelastosis	0.700	0.300	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.700	0.300	0.000
E03.5 Myxoedema coma	0.699	0.300	0.000
E03.4 Atrophy of thyroid (acquired)	0.699	0.300	0.000
E03.3 Postinfectious hypothyroidism	0.699	0.300	0.000
E03.1 Congenital hypothyroidism without goitre	0.699	0.300	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.699	0.300	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.697	0.303	0.000
C70 Malignant neoplasm of meninges	0.697	0.303	0.000
I00-I02 Acute rheumatic fever	0.697	0.303	0.000
C34.1 Upper lobe, bronchus or lung	0.697	0.303	0.000
M35.3 Polymyalgia rheumatica	0.697	0.303	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.696	0.304	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.696	0.304	0.000
F44 Dissociative [conversion] disorders	0.695	0.305	0.000
I31.3 Pericardial effusion (noninflammatory)	0.695	0.305	0.000
H90 Conductive and sensorineural hearing loss	0.695	0.305	0.000
C16.2 Body of stomach	0.694	0.306	0.000
J43.8 Other emphysema	0.692	0.308	0.000
J43.1 Panlobular emphysema	0.692	0.308	0.000
J43.0 MacLeod's syndrome	0.692	0.308	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.691	0.309	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.691	0.309	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.691	0.309	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.691	0.309	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.691	0.309	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.691	0.309	0.000
J84.8 Other specified interstitial pulmonary diseases	0.690	0.309	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.689	0.310	0.000
E00 Congenital iodine-deficiency syndrome	0.689	0.310	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.689	0.310	0.000
F41.2 Mixed anxiety and depressive disorder	0.689	0.311	0.000
F10.8 Other mental and behavioural disorders	0.687	0.313	0.000
F10.7 Residual and late-onset psychotic disorder	0.687	0.313	0.000
F10.6 Amnesic syndrome	0.687	0.313	0.000
F10.5 Psychotic disorder	0.687	0.313	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.686	0.313	0.000
C21.2 Cloacogenic zone	0.686	0.313	0.000
D12.7 Rectosigmoid junction	0.686	0.314	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.686	0.314	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.685	0.315	0.000
M06.38 Rheumatoid nodule (Other)	0.685	0.315	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.685	0.315	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.685	0.315	0.000
M06.33 Rheumatoid nodule (Forearm)	0.685	0.315	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.685	0.315	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.685	0.315	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.685	0.315	0.000
D35.2 Pituitary gland	0.684	0.316	0.000
S10-S19 Injuries to the neck	0.684	0.316	0.000
C26.0 Intestinal tract, part unspecified	0.684	0.316	0.000
S27 Injury of other and unspecified intrathoracic organs	0.683	0.317	0.000
I47.0 Reentry ventricular arrhythmia	0.683	0.317	0.000
F10.9 Unspecified mental and behavioural disorder	0.682	0.318	0.000
F38 Other mood [affective] disorders	0.682	0.318	0.000
F34 Persistent mood [affective] disorders	0.682	0.318	0.000
C71.8 Overlapping lesion of brain	0.682	0.318	0.000
C71.7 Brain stem	0.682	0.318	0.000
C71.6 Cerebellum	0.682	0.318	0.000
C71.5 Cerebral ventricle	0.682	0.318	0.000
C71.4 Occipital lobe	0.682	0.318	0.000
D06.0 Endocervix	0.682	0.318	0.000
M41 Scoliosis	0.681	0.319	0.000
D09.0 Bladder	0.681	0.319	0.000
F80-F89 Disorders of psychological development	0.680	0.320	0.000
J20 Acute bronchitis	0.678	0.322	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.678	0.322	0.000
F11 Mental and behavioural disorders due to use of opioids	0.676	0.324	0.000
F43 Reaction to severe stress, and adjustment disorders	0.675	0.325	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.674	0.326	0.000
J14 Pneumonia due to Haemophilus influenzae	0.672	0.328	0.000
M86-M90 Other osteopathies	0.672	0.328	0.000
E04.9 Non-toxic goitre, unspecified	0.672	0.328	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.668	0.332	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.668	0.332	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.668	0.332	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.668	0.332	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.668	0.332	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.668	0.332	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.668	0.332	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.668	0.332	0.000
C16.6 Greater curvature of stomach, unspecified	0.667	0.333	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.667	0.333	0.000
D07.6 Other and unspecified male genital organs	0.667	0.333	0.000
D07.3 Other and unspecified female genital organs	0.667	0.333	0.000
D07.2 Vagina	0.667	0.333	0.000
D07.0 Endometrium	0.667	0.333	0.000
J45.0 Predominantly allergic asthma	0.666	0.334	0.000
S32 Fracture of lumbar spine and pelvis	0.666	0.334	0.000
D00.0 Lip, oral cavity and pharynx	0.665	0.335	0.000
F31.8 Other bipolar affective disorders	0.664	0.336	0.000
F31.7 Bipolar affective disorder, currently in remission	0.664	0.336	0.000
C71.2 Temporal lobe	0.664	0.336	0.000
I30 Acute pericarditis	0.664	0.336	0.000
H65-H75 Diseases of middle ear and mastoid	0.662	0.338	0.000
C18.9 Colon, unspecified	0.659	0.341	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.659	0.341	0.000
D16 Benign neoplasm of bone and articular cartilage	0.658	0.342	0.000
E40-E46 Malnutrition	0.658	0.342	0.000
C04 Malignant neoplasm of floor of mouth	0.657	0.343	0.000
H81 Disorders of vestibular function	0.656	0.343	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.655	0.345	0.000
C13 Malignant neoplasm of hypopharynx	0.654	0.346	0.000
C11 Malignant neoplasm of nasopharynx	0.654	0.346	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.654	0.346	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.654	0.346	0.000
C03 Malignant neoplasm of gum	0.654	0.346	0.000
C00 Malignant neoplasm of lip	0.654	0.346	0.000
C12 Malignant neoplasm of pyriform sinus	0.654	0.346	0.000
F39 Unspecified mood [affective] disorder	0.654	0.346	0.000
C16.3 Pyloric antrum	0.653	0.347	0.000
D01.3 Anus and anal canal	0.653	0.347	0.000
F45.8 Other somatoform disorders	0.653	0.347	0.000
C15 Malignant neoplasm of oesophagus	0.650	0.350	0.000
M10 Gout	0.650	0.350	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.649	0.351	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.649	0.351	0.000
D29 Benign neoplasm of male genital organs	0.647	0.352	0.000
I06 Rheumatic aortic valve diseases	0.647	0.353	0.000
F30 Manic episode	0.647	0.353	0.000
I33 Acute and subacute endocarditis	0.646	0.353	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.645	0.355	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.645	0.355	0.000
E04.1 Non-toxic single thyroid nodule	0.644	0.355	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.643	0.357	0.000
D23 Other benign neoplasms of skin	0.643	0.357	0.000
E07 Other disorders of thyroid	0.643	0.357	0.000
F32.0 Mild depressive episode	0.643	0.357	0.000
M94 Other disorders of cartilage	0.642	0.358	0.000
Q80-Q89 Other congenital malformations	0.642	0.358	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.641	0.359	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.641	0.359	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.641	0.359	0.000
C31 Malignant neoplasm of accessory sinuses	0.641	0.359	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.641	0.359	0.000
C37 Malignant neoplasm of thymus	0.641	0.359	0.000
C33 Malignant neoplasm of trachea	0.641	0.359	0.000
C18.4 Transverse colon	0.641	0.359	0.000
M31.6 Other giant cell arteritis	0.641	0.359	0.000
C18.0 Caecum	0.640	0.360	0.000
C09 Malignant neoplasm of tonsil	0.640	0.360	0.000
M34 Systemic sclerosis	0.640	0.360	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.639	0.361	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.638	0.362	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.362	0.638
S32.5 Fracture of pubis	0.638	0.362	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.637	0.363	0.000
J81 Pulmonary oedema	0.637	0.363	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.636	0.364	0.000
M33 Dermatopolymyositis	0.636	0.364	0.000
J96 Respiratory failure, not elsewhere classified	0.635	0.365	0.000
E03.8 Other specified hypothyroidism	0.635	0.365	0.000
T66-T78 Other and unspecified effects of external causes	0.634	0.366	0.000
C16.9 Stomach, unspecified	0.633	0.367	0.000
M14 Arthropathies in other diseases classified elsewhere	0.633	0.367	0.000
M30 Polyarteritis nodosa and related conditions	0.633	0.367	0.000
D04 Carcinoma in situ of skin	0.632	0.368	0.000
H81.1 Benign paroxysmal vertigo	0.631	0.369	0.000
J84.0 Alveolar and parietoalveolar conditions	0.631	0.369	0.000
D05 Carcinoma in situ of breast	0.628	0.372	0.000
C17.9 Small intestine, unspecified	0.628	0.372	0.000
J42 Unspecified chronic bronchitis	0.627	0.372	0.000
S50 Superficial injury of forearm	0.627	0.373	0.000
S70-S79 Injuries to the hip and thigh	0.626	0.374	0.000
C16.5 Lesser curvature of stomach, unspecified	0.625	0.374	0.000
J43.2 Centrilobular emphysema	0.625	0.375	0.000
F33 Recurrent depressive disorder	0.624	0.376	0.000
M40 Kyphosis and lordosis	0.624	0.376	0.000
I08.9 Multiple valve disease, unspecified	0.622	0.378	0.000
C22.0 Liver cell carcinoma	0.621	0.379	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.620	0.379	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.620	0.379	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.620	0.379	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.620	0.379	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.620	0.379	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.620	0.379	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.620	0.379	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.620	0.379	0.000
I47.1 Supraventricular tachycardia	0.620	0.380	0.000
I46.1 Sudden cardiac death, so described	0.620	0.380	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.620	0.380	0.000
D26 Other benign neoplasms of uterus	0.619	0.380	0.000
C10 Malignant neoplasm of oropharynx	0.618	0.381	0.000
T79-T79 Certain early complications of trauma	0.618	0.382	0.000
S32.50 Fracture of pubis (closed)	0.618	0.382	0.000
M22.4 Chondromalacia patellae	0.616	0.383	0.000
I08.8 Other multiple valve diseases	0.615	0.385	0.000
C71.3 Parietal lobe	0.615	0.385	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.615	0.385	0.000
M32 Systemic lupus erythematosus	0.615	0.385	0.000
S51.0 Open wound of elbow	0.614	0.386	0.000
C16.8 Overlapping lesion of stomach	0.614	0.386	0.000
C16.4 Pylorus	0.614	0.386	0.000
C16.1 Fundus of stomach	0.614	0.386	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.610	0.389	0.000
D06.7 Other parts of cervix	0.610	0.390	0.000
D06.1 Exocervix	0.610	0.390	0.000
J11 Influenza, virus not identified	0.610	0.390	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.608	0.392	0.000
C18.2 Ascending colon	0.608	0.392	0.000
C16.0 Cardia	0.605	0.395	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.604	0.396	0.000
M00 Pyogenic arthritis	0.603	0.396	0.000
M43 Other deforming dorsopathies	0.603	0.397	0.000
J60-J70 Lung diseases due to external agents	0.602	0.398	0.000
D31 Benign neoplasm of eye and adnexa	0.601	0.399	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.601	0.399	0.000
D19 Benign neoplasm of mesothelial tissue	0.601	0.399	0.000
I37 Pulmonary valve disorders	0.600	0.399	0.000
M31.9 Necrotising vasculopathy, unspecified	0.595	0.405	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.594	0.405	0.000
C05.1 Soft palate	0.594	0.406	0.000
C02.1 Border of tongue	0.594	0.406	0.000
M21 Other acquired deformities of limbs	0.594	0.406	0.000
M42 Spinal osteochondrosis	0.593	0.407	0.000
J95.0 Tracheostomy malfunction	0.593	0.407	0.000
H74 Other disorders of middle ear and mastoid	0.591	0.408	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.591	0.409	0.000
F60-F69 Disorders of adult personality and behaviour	0.589	0.410	0.001
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.589	0.411	0.000
S27.3 Other injuries of lung	0.589	0.411	0.000
S56 Injury of muscle and tendon at forearm level	0.588	0.412	0.000
M11.2 Other chondrocalcinosis	0.587	0.412	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.587	0.413	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.587	0.413	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.587	0.413	0.000
S27.0 Traumatic pneumothorax	0.586	0.413	0.000
M35.1 Other overlap syndromes	0.586	0.414	0.000
M20 Acquired deformities of fingers and toes	0.586	0.414	0.000
C69.3 Choroid	0.586	0.414	0.000
D10 Benign neoplasm of mouth and pharynx	0.585	0.414	0.000
D34 Benign neoplasm of thyroid gland	0.585	0.415	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.584	0.415	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.584	0.416	0.000
S51.8 Open wound of other parts of forearm	0.583	0.417	0.000
J15.4 Pneumonia due to other streptococci	0.582	0.417	0.000
C26.9 Ill-defined sites within the digestive system	0.582	0.418	0.000
C26.8 Overlapping lesion of digestive system	0.582	0.418	0.000
C26.1 Spleen	0.582	0.418	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.582	0.418	0.000
F99 Mental disorder, not otherwise specified	0.582	0.418	0.000
E04.2 Non-toxic multinodular goitre	0.582	0.418	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.582	0.418	0.000
I51.6 Cardiovascular disease, unspecified	0.582	0.418	0.000
Chapter XX External causes of morbidity and mortality	0.582	0.418	0.000
T33-T35 Frostbite	0.581	0.418	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.581	0.418	0.000
I51.5 Myocardial degeneration	0.581	0.418	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.581	0.418	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.581	0.418	0.000
I51.0 Cardiac septal defect, acquired	0.581	0.418	0.000
S59 Other and unspecified injuries of forearm	0.581	0.419	0.000
I51.4 Myocarditis, unspecified	0.581	0.419	0.000
E04.8 Other specified non-toxic goitre	0.580	0.419	0.000
C14.0 Pharynx, unspecified	0.580	0.420	0.000
S92 Fracture of foot, except ankle	0.580	0.420	0.000
D02.0 Larynx	0.580	0.420	0.000
Q43 Other congenital malformations of intestine	0.579	0.421	0.000
D09.9 Carcinoma in situ, unspecified	0.579	0.421	0.000
D09.7 Carcinoma in situ of other specified sites	0.579	0.421	0.000
D09.3 Thyroid and other endocrine glands	0.579	0.421	0.000
D09.2 Eye	0.579	0.421	0.000
D09.1 Other and unspecified urinary organs	0.579	0.421	0.000
D32 Benign neoplasm of meninges	0.578	0.422	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.578	0.422	0.000
S54 Injury of nerves at forearm level	0.577	0.423	0.000
F48.0 Neurasthenia	0.577	0.423	0.000
F32.1 Moderate depressive episode	0.577	0.423	0.000
M41.9 Scoliosis, unspecified	0.577	0.423	0.000
T00-T07 Injuries involving multiple body regions	0.576	0.424	0.000
S51.7 Multiple open wounds of forearm	0.575	0.425	0.000
I05 Rheumatic mitral valve diseases	0.574	0.426	0.000
I31.8 Other specified diseases of pericardium	0.574	0.426	0.000
I31.2 Haemopericardium, not elsewhere classified	0.574	0.426	0.000
I31.1 Chronic constrictive pericarditis	0.574	0.426	0.000
I31.0 Chronic adhesive pericarditis	0.574	0.426	0.000
D03.5 Melanoma in situ of trunk	0.573	0.426	0.000
J80 Adult respiratory distress syndrome	0.573	0.427	0.000
H91 Other hearing loss	0.573	0.427	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.573	0.427	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.573	0.427	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.573	0.427	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.573	0.427	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.573	0.427	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.573	0.427	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.573	0.427	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.573	0.427	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.573	0.427	0.000
D00.2 Stomach	0.572	0.428	0.000
D00.1 Oesophagus	0.572	0.428	0.000
D23.1 Skin of eyelid, including canthus	0.572	0.428	0.000
M24 Other specific joint derangements	0.571	0.429	0.000
F10.3 Withdrawal state	0.571	0.429	0.000
D12.1 Appendix	0.570	0.430	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations