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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78554423
log Bayes Factor = 15.8567
Chromosome 18   position 27,227,214  (GRCh37) Explore rs78554423 on Ensembl!
Variant rs78554423 is part of Cluster X0045

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
Chapter XIV Diseases of the genitourinary system
0.991 0.009 0.000
D10-D36 Benign neoplasms
0.991 0.009 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.985 0.015 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.982 0.018 0.000
B95-B98 Bacterial, viral and other infectious agents
0.981 0.019 0.000
I35 Nonrheumatic aortic valve disorders
0.976 0.024 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.976 0.024 0.000
R50-R69 General symptoms and signs
0.973 0.027 0.000
D25 Leiomyoma of uterus
0.972 0.028 0.000
L57.0 Actinic keratosis
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.968 0.032 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.966 0.034 0.000
Chapter VI Diseases of the nervous system
0.965 0.035 0.000
Chapter X Diseases of the respiratory system
0.964 0.036 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.964 0.036 0.000
Chapter XXI Factors influencing health status and contact with health services
0.962 0.038 0.000
R55 Syncope and collapse
0.957 0.043 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.956 0.044 0.000
I44 Atrioventricular and left bundle-branch block
0.954 0.046 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.954 0.046 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.954 0.046 0.000
Z95.4 Presence of other heart-valve replacement
0.953 0.047 0.000
C15-C26 Malignant neoplasms of digestive organs
0.952 0.048 0.000
D25.9 Leiomyoma of uterus, unspecified
0.950 0.050 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.950 0.050 0.000
M50-M54 Other dorsopathies
0.945 0.055 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.942 0.058 0.000
N20-N23 Urolithiasis
0.941 0.059 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.940 0.060 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.934 0.066 0.000
M20-M25 Other joint disorders
0.929 0.071 0.000
N25-N29 Other disorders of kidney and ureter
0.923 0.077 0.000
L90 Atrophic disorders of skin
0.923 0.077 0.000
Z95.2 Presence of prosthetic heart valve
0.923 0.077 0.000
A30-A49 Other bacterial diseases
0.920 0.080 0.000
J09-J18 Influenza and pneumonia
0.918 0.082 0.000
I35.1 Aortic (valve) insufficiency
0.912 0.088 0.000
D32 Benign neoplasm of meninges
0.909 0.091 0.000
I95 Hypotension
0.909 0.091 0.000
N23 Unspecified renal colic
0.907 0.093 0.000
I05-I09 Chronic rheumatic heart diseases
0.906 0.094 0.000
L90.5 Scar conditions and fibrosis of skin
0.905 0.095 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.903 0.097 0.000
N00-N08 Glomerular diseases
0.903 0.097 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.903 0.097 0.000
M54 Dorsalgia
0.902 0.098 0.000
M23 Internal derangement of knee
0.900 0.100 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.898 0.102 0.000
L03 Cellulitis
0.894 0.106 0.000
E10-E14 Diabetes mellitus
0.893 0.107 0.000
N10-N16 Renal tubulo-interstitial diseases
0.892 0.108 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.891 0.109 0.000
J20-J22 Other acute lower respiratory infections
0.889 0.111 0.000
R63 Symptoms and signs concerning food and fluid intake
0.888 0.112 0.000
E65-E68 Obesity and other hyperalimentation
0.887 0.113 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.883 0.117 0.000
C20 Malignant neoplasm of rectum
0.881 0.119 0.000
M05-M14 Inflammatory polyarthropathies
0.880 0.120 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.879 0.121 0.000
F10.1 Harmful use
0.877 0.123 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.877 0.123 0.000
M54.1 Radiculopathy
0.875 0.125 0.000
I44.0 Atrioventricular block, first degree
0.874 0.126 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.873 0.127 0.000
R00 Abnormalities of heart beat
0.872 0.128 0.000
F10.0 Acute intoxication
0.870 0.130 0.000
F10.2 Dependence syndrome
0.869 0.131 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.869 0.131 0.000
L03.1 Cellulitis of other parts of limb
0.869 0.131 0.000
D00-D09 In situ neoplasms
0.867 0.133 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.867 0.133 0.000
I45 Other conduction disorders
0.865 0.135 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.865 0.135 0.000
I95.1 Orthostatic hypotension
0.864 0.136 0.000
N72 Inflammatory disease of cervix uteri
0.863 0.137 0.000
J18 Pneumonia, organism unspecified
0.863 0.137 0.000
Z95.1 Presence of aortocoronary bypass graft
0.862 0.138 0.000
I50 Heart failure
0.861 0.139 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.857 0.143 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.856 0.144 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.855 0.145 0.000
D27 Benign neoplasm of ovary
0.853 0.147 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.853 0.147 0.000
D24 Benign neoplasm of breast
0.852 0.148 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.850 0.150 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.850 0.150 0.000
I78 Diseases of capillaries
0.849 0.151 0.000
I33 Acute and subacute endocarditis
0.849 0.151 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.846 0.154 0.000
Chapter XX External causes of morbidity and mortality
0.844 0.156 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.844 0.156 0.000
R63.4 Abnormal weight loss
0.842 0.158 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.841 0.159 0.000
C60-C63 Malignant neoplasms of male genital organs
0.840 0.160 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.838 0.162 0.000
R00.1 Bradycardia, unspecified
0.837 0.163 0.000
M80-M85 Disorders of bone density and structure
0.837 0.163 0.000
G30-G32 Other degenerative diseases of the nervous system
0.837 0.163 0.000
A41 Other septicaemia
0.836 0.164 0.000
J22 Unspecified acute lower respiratory infection
0.834 0.166 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.834 0.166 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.832 0.168 0.000
M54.16 Radiculopathy (Lumbar region)
0.832 0.168 0.000
I49 Other cardiac arrhythmias
0.829 0.171 0.000
E66 Obesity
0.828 0.172 0.000
R50 Fever of unknown origin
0.828 0.172 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.827 0.173 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.825 0.175 0.000
I84 Haemorrhoids
0.822 0.178 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.821 0.179 0.000
D32.0 Cerebral meninges
0.821 0.179 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.820 0.180 0.000
Z60 Problems related to social environment
0.820 0.180 0.000
I42 Cardiomyopathy
0.817 0.183 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.816 0.184 0.000
R51 Headache
0.815 0.185 0.000
I08 Multiple valve diseases
0.815 0.185 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.814 0.186 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.813 0.187 0.000
E50-E64 Other nutritional deficiencies
0.812 0.188 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.812 0.188 0.000
R53 Malaise and fatigue
0.811 0.189 0.000
I60-I69 Cerebrovascular diseases
0.811 0.189 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.808 0.192 0.000
E10 Insulin-dependent diabetes mellitus
0.807 0.193 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.806 0.194 0.000
C18 Malignant neoplasm of colon
0.806 0.194 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.805 0.195 0.000
F99-F99 Unspecified mental disorder
0.803 0.197 0.000
M54.9 Dorsalgia, unspecified
0.802 0.198 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.801 0.199 0.000
J90-J94 Other diseases of pleura
0.799 0.201 0.000
N03 Chronic nephritic syndrome
0.796 0.204 0.000
I44.1 Atrioventricular block, second degree
0.795 0.205 0.000
J18.1 Lobar pneumonia, unspecified
0.793 0.207 0.000
I44.3 Other and unspecified atrioventricular block
0.791 0.209 0.000
D10 Benign neoplasm of mouth and pharynx
0.791 0.209 0.000
D34 Benign neoplasm of thyroid gland
0.790 0.210 0.000
D25.0 Submucous leiomyoma of uterus
0.789 0.211 0.000
I78.1 Naevus, nonneoplastic
0.788 0.212 0.000
D30 Benign neoplasm of urinary organs
0.786 0.214 0.000
I84.2 Internal haemorrhoids without complication
0.786 0.214 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.786 0.214 0.000
I99 Other and unspecified disorders of circulatory system
0.785 0.215 0.000
M35 Other systemic involvement of connective tissue
0.785 0.215 0.000
Z94 Transplanted organ and tissue status
0.785 0.215 0.000
M91-M94 Chondropathies
0.783 0.217 0.000
J60-J70 Lung diseases due to external agents
0.782 0.218 0.000
N28.1 Cyst of kidney, acquired
0.781 0.219 0.000
Z83 Family history of other specific disorders
0.781 0.219 0.000
Z60.2 Living alone
0.780 0.220 0.000
R05 Cough
0.779 0.221 0.000
N30-N39 Other diseases of urinary system
0.778 0.222 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.777 0.223 0.000
I35.8 Other aortic valve disorders
0.777 0.223 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.775 0.225 0.000
I27 Other pulmonary heart diseases
0.775 0.225 0.000
D25.1 Intramural leiomyoma of uterus
0.772 0.228 0.000
L94 Other localised connective tissue disorders
0.771 0.229 0.000
M86-M90 Other osteopathies
0.769 0.230 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.769 0.231 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.767 0.233 0.000
Z89 Acquired absence of limb
0.766 0.234 0.000
F10.3 Withdrawal state
0.765 0.234 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.763 0.237 0.000
G90-G99 Other disorders of the nervous system
0.762 0.238 0.000
G20-G26 Extrapyramidal and movement disorders
0.761 0.239 0.000
M60-M63 Disorders of muscles
0.760 0.239 0.000
R58 Haemorrhage, not elsewhere classified
0.760 0.240 0.000
I35.0 Aortic (valve) stenosis
0.760 0.240 0.000
R57 Shock, not elsewhere classified
0.759 0.241 0.000
E16 Other disorders of pancreatic internal secretion
0.759 0.241 0.000
E66.9 Obesity, unspecified
0.759 0.241 0.000
M22 Disorders of patella
0.758 0.242 0.000
L03.8 Cellulitis of other sites
0.757 0.243 0.000
A49 Bacterial infection of unspecified site
0.756 0.244 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.755 0.245 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.754 0.246 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.752 0.248 0.000
I80 Phlebitis and thrombophlebitis
0.751 0.249 0.000
C25 Malignant neoplasm of pancreas
0.750 0.249 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.750 0.250 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.749 0.251 0.000
B25-B34 Other viral diseases
0.749 0.251 0.000
I95.9 Hypotension, unspecified
0.748 0.252 0.000
D11 Benign neoplasm of major salivary glands
0.748 0.252 0.000
I45.1 Other and unspecified right bundle-branch block
0.747 0.253 0.000
N26 Unspecified contracted kidney
0.746 0.254 0.000
Z97 Presence of other devices
0.746 0.254 0.000
I84.3 External thrombosed haemorrhoids
0.746 0.254 0.000
C64-C68 Malignant neoplasms of urinary tract
0.746 0.254 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.744 0.256 0.000
M51 Other intervertebral disk disorders
0.743 0.257 0.000
I33.0 Acute and subacute infective endocarditis
0.742 0.258 0.000
A80-A89 Viral infections of the central nervous system
0.741 0.259 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.741 0.259 0.000
I87 Other disorders of veins
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.740 0.260 0.000
D06 Carcinoma in situ of cervix uteri
0.739 0.261 0.000
I50.0 Congestive heart failure
0.739 0.261 0.000
J18.9 Pneumonia, unspecified
0.738 0.262 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.738 0.262 0.000
M34 Systemic sclerosis
0.738 0.262 0.000
I44.7 Left bundle-branch block, unspecified
0.738 0.262 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.737 0.263 0.000
M23.8 Other internal derangements of knee
0.736 0.264 0.000
C61 Malignant neoplasm of prostate
0.736 0.264 0.000
R56 Convulsions, not elsewhere classified
0.736 0.264 0.000
D32.9 Meninges, unspecified
0.736 0.264 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.735 0.265 0.000
I05 Rheumatic mitral valve diseases
0.735 0.265 0.000
R73 Elevated blood glucose level
0.735 0.265 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.733 0.267 0.000
D36 Benign neoplasm of other and unspecified sites
0.733 0.267 0.000
M10 Gout
0.733 0.267 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.732 0.268 0.000
R52 Pain, not elsewhere classified
0.731 0.269 0.000
G62 Other polyneuropathies
0.730 0.270 0.000
R00.0 Tachycardia, unspecified
0.730 0.270 0.000
D26 Other benign neoplasms of uterus
0.728 0.272 0.000
Z80 Family history of malignant neoplasm
0.728 0.272 0.000
Z93 Artificial opening status
0.727 0.273 0.000
I63 Cerebral infarction
0.727 0.273 0.000
I08.0 Disorders of both mitral and aortic valves
0.726 0.274 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.726 0.274 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.726 0.274 0.000
I46 Cardiac arrest
0.725 0.275 0.000
L82 Seborrhoeic keratosis
0.725 0.275 0.000
N70 Salpingitis and oophoritis
0.724 0.276 0.000
Z95.0 Presence of cardiac pacemaker
0.724 0.276 0.000
I47 Paroxysmal tachycardia
0.723 0.276 0.000
D18 Haemangioma and lymphangioma, any site
0.723 0.277 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.723 0.277 0.000
L84 Corns and callosities
0.720 0.280 0.000
N03.9 Unspecified
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E10.9 Without complications
0.717 0.283 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.714 0.286 0.000
R50.9 Fever, unspecified
0.713 0.287 0.000
L50-L54 Urticaria and erythema
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.712 0.288 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.712 0.288 0.000
E40-E46 Malnutrition
0.712 0.288 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
D31 Benign neoplasm of eye and adnexa
0.711 0.289 0.000
D29 Benign neoplasm of male genital organs
0.711 0.289 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.711 0.289 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.711 0.289 0.000
D19 Benign neoplasm of mesothelial tissue
0.711 0.289 0.000
D16 Benign neoplasm of bone and articular cartilage
0.711 0.289 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.711 0.289 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.710 0.290 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.710 0.290 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.709 0.291 0.000
M24 Other specific joint derangements
0.708 0.291 0.000
R06 Abnormalities of breathing
0.708 0.292 0.000
E11 Non-insulin-dependent diabetes mellitus
0.707 0.293 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.706 0.293 0.000
L58 Radiodermatitis
0.706 0.293 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.706 0.293 0.000
L55 Sunburn
0.706 0.293 0.000
J14 Pneumonia due to Haemophilus influenzae
0.706 0.294 0.000
M54.12 Radiculopathy (Cervical region)
0.706 0.294 0.000
I42.9 Cardiomyopathy, unspecified
0.706 0.294 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.706 0.294 0.000
R80 Isolated proteinuria
0.705 0.295 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.704 0.296 0.000
I86 Varicose veins of other sites
0.704 0.296 0.000
F30-F39 Mood [affective] disorders
0.703 0.297 0.000
R47-R49 Symptoms and signs involving speech and voice
0.703 0.297 0.000
L81 Other disorders of pigmentation
0.703 0.297 0.000
E20-E35 Disorders of other endocrine glands
0.703 0.297 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.702 0.297 0.000
E53 Deficiency of other B group vitamins
0.702 0.298 0.000
Z95.3 Presence of xenogenic heart valve
0.701 0.299 0.000
I35.9 Aortic valve disorder, unspecified
0.700 0.300 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F80-F89 Disorders of psychological development
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
F60-F69 Disorders of adult personality and behaviour
0.700 0.300 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.700 0.300 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.700 0.300 0.000
L57.5 Actinic granuloma
0.700 0.300 0.000
L57.4 Cutis laxa senilis
0.700 0.300 0.000
L57.3 Poikiloderma of Civatte
0.700 0.300 0.000
L57.2 Cutis rhomboidalis nuchae
0.700 0.300 0.000
L57.1 Actinic reticuloid
0.700 0.300 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.699 0.300 0.000
B15-B19 Viral hepatitis
0.698 0.302 0.000
Chapter XXII Codes for special purposes
0.698 0.302 0.000
R00.2 Palpitations
0.698 0.302 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.698 0.302 0.000
R62 Lack of expected normal physiological development
0.698 0.302 0.000
R64 Cachexia
0.698 0.302 0.000
Chapter VII Diseases of the eye and adnexa
0.697 0.303 0.000
E16.2 Hypoglycaemia, unspecified
0.696 0.304 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.695 0.305 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.693 0.307 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.693 0.307 0.000
L93 Lupus erythematosus
0.693 0.307 0.000
L87 Transepidermal elimination disorders
0.693 0.307 0.000
L88 Pyoderma gangrenosum
0.693 0.307 0.000
L86 Keratoderma in diseases classified elsewhere
0.693 0.307 0.000
L83 Acanthosis nigricans
0.693 0.307 0.000
L80 Vitiligo
0.693 0.307 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.693 0.307 0.000
I84.4 External haemorrhoids with other complications
0.693 0.307 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.692 0.308 0.000
S70-S79 Injuries to the hip and thigh
0.691 0.309 0.000
M11 Other crystal arthropathies
0.691 0.309 0.000
N39 Other disorders of urinary system
0.690 0.310 0.000
I63.9 Cerebral infarction, unspecified
0.690 0.310 0.000
G61 Inflammatory polyneuropathy
0.688 0.312 0.000
E66.8 Other obesity
0.688 0.312 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.687 0.313 0.000
I49.3 Ventricular premature depolarisation
0.687 0.313 0.000
M06 Other rheumatoid arthritis
0.687 0.313 0.000
G60 Hereditary and idiopathic neuropathy
0.686 0.314 0.000
I45.2 Bifascicular block
0.686 0.314 0.000
I73 Other peripheral vascular diseases
0.685 0.315 0.000
I72 Other aneurysm
0.685 0.315 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.685 0.315 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.685 0.315 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.685 0.315 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.685 0.315 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.685 0.315 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.685 0.315 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.685 0.315 0.000
F11 Mental and behavioural disorders due to use of opioids
0.685 0.315 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.685 0.315 0.000
C71 Malignant neoplasm of brain
0.685 0.315 0.000
M07 Psoriatic and enteropathic arthropathies
0.684 0.316 0.000
J84 Other interstitial pulmonary diseases
0.684 0.316 0.000
I44.6 Other and unspecified fascicular block
0.684 0.316 0.000
I44.5 Left posterior fascicular block
0.684 0.316 0.000
I44.4 Left anterior fascicular block
0.684 0.316 0.000
Z84 Family history of other conditions
0.684 0.316 0.000
Z81 Family history of mental and behavioural disorders
0.684 0.316 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.684 0.316 0.000
N02 Recurrent and persistent haematuria
0.683 0.317 0.000
Y95 Nosocomial condition
0.682 0.318 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.682 0.318 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.682 0.318 0.000
C21 Malignant neoplasm of anus and anal canal
0.682 0.318 0.000
C17 Malignant neoplasm of small intestine
0.682 0.318 0.000
C23 Malignant neoplasm of gallbladder
0.682 0.318 0.000
G70-G73 Diseases of myoneural junction and muscle
0.681 0.319 0.000
F10.9 Unspecified mental and behavioural disorder
0.681 0.319 0.000
F10.8 Other mental and behavioural disorders
0.681 0.319 0.000
F10.7 Residual and late-onset psychotic disorder
0.681 0.319 0.000
F10.6 Amnesic syndrome
0.681 0.319 0.000
F10.5 Psychotic disorder
0.681 0.319 0.000
F10.4 Withdrawal state with delirium
0.681 0.319 0.000
J95-J99 Other diseases of the respiratory system
0.680 0.320 0.000
I27.0 Primary pulmonary hypertension
0.680 0.320 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.680 0.320 0.000
N99-N99 Other disorders of the genitourinary system
0.679 0.320 0.000
O47 False labour
0.679 0.321 0.000
F99 Mental disorder, not otherwise specified
0.679 0.321 0.000
N39.3 Stress incontinence
0.678 0.322 0.000
E14 Unspecified diabetes mellitus
0.678 0.322 0.000
M53 Other dorsopathies, not elsewhere classified
0.677 0.322 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.677 0.323 0.000
J11 Influenza, virus not identified
0.676 0.323 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.675 0.324 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.675 0.324 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.675 0.325 0.000
O20 Haemorrhage in early pregnancy
0.674 0.326 0.000
L04 Acute lymphadenitis
0.674 0.326 0.000
L01 Impetigo
0.674 0.326 0.000
L00 Staphylococcal scalded skin syndrome
0.674 0.326 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.673 0.327 0.000
Z99.3 Dependence on wheelchair
0.673 0.327 0.000
C51-C58 Malignant neoplasms of female genital organs
0.673 0.327 0.000
L03.9 Cellulitis, unspecified
0.672 0.327 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.672 0.328 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.672 0.328 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.672 0.328 0.000
M50 Cervical disk disorders
0.672 0.328 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.670 0.329 0.000
X60-X84 Intentional self-harm
0.670 0.330 0.000
N05 Unspecified nephritic syndrome
0.670 0.330 0.000
L89 Decubitus ulcer
0.670 0.330 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.670 0.330 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.670 0.330 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.670 0.330 0.000
N20 Calculus of kidney and ureter
0.669 0.330 0.000
I49.5 Sick sinus syndrome
0.669 0.331 0.000
I27.2 Other secondary pulmonary hypertension
0.669 0.331 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.669 0.331 0.000
N21 Calculus of lower urinary tract
0.668 0.331 0.000
M35.3 Polymyalgia rheumatica
0.668 0.332 0.000
M84 Disorders of continuity of bone
0.667 0.333 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.667 0.333 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.666 0.334 0.000
M33 Dermatopolymyositis
0.666 0.334 0.000
M32 Systemic lupus erythematosus
0.666 0.334 0.000
M30 Polyarteritis nodosa and related conditions
0.666 0.334 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.665 0.335 0.000
L03.0 Cellulitis of finger and toe
0.664 0.336 0.000
D13.0 Oesophagus
0.664 0.336 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.663 0.337 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.662 0.338 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.662 0.338 0.000
N27 Small kidney of unknown cause
0.662 0.338 0.000
N25 Disorders resulting from impaired renal tubular function
0.662 0.338 0.000
L90.9 Atrophic disorder of skin, unspecified
0.662 0.338 0.000
L90.8 Other atrophic disorders of skin
0.662 0.338 0.000
L90.6 Striae atrophicae
0.662 0.338 0.000
L90.4 Acrodermatitis chronica atrophicans
0.662 0.338 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.662 0.338 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.662 0.338 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.662 0.338 0.000
L05 Pilonidal cyst
0.661 0.338 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.661 0.339 0.000
M54.4 Lumbago with sciatica
0.661 0.339 0.000
Z99.1 Dependence on respirator
0.660 0.340 0.000
A48 Other bacterial diseases, not elsewhere classified
0.659 0.340 0.000
A44 Bartonellosis
0.659 0.340 0.000
A43 Nocardiosis
0.659 0.340 0.000
A42 Actinomycosis
0.659 0.340 0.000
A40 Streptococcal septicaemia
0.659 0.340 0.000
A39 Meningococcal infection
0.659 0.340 0.000
A37 Whooping cough
0.659 0.340 0.000
A36 Diphtheria
0.659 0.340 0.000
A32 Listeriosis
0.659 0.340 0.000
A31 Infection due to other mycobacteria
0.659 0.340 0.000
A30 Leprosy [Hansen's disease]
0.659 0.340 0.000
A46 Erysipelas
0.659 0.340 0.000
A38 Scarlet fever
0.659 0.340 0.000
A35 Other tetanus
0.659 0.340 0.000
A34 Obstetrical tetanus
0.659 0.340 0.000
A33 Tetanus neonatorum
0.659 0.340 0.000
L85 Other epidermal thickening
0.659 0.341 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.658 0.342 0.000
J17 Pneumonia in diseases classified elsewhere
0.658 0.342 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.658 0.342 0.000
J12 Viral pneumonia, not elsewhere classified
0.658 0.342 0.000
J10 Influenza due to identified influenza virus
0.658 0.342 0.000
J09 Influenza due to certain identified influenza virus
0.658 0.342 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.658 0.342 0.000
R50.8 Other specified fever
0.657 0.342 0.000
I69 Sequelae of cerebrovascular disease
0.657 0.343 0.000
M40-M43 Deforming dorsopathies
0.656 0.344 0.000
M65-M68 Disorders of synovium and tendon
0.654 0.346 0.000
W00-W19 Falls
0.654 0.346 0.000
O80-O84 Delivery
0.654 0.346 0.000
J94 Other pleural conditions
0.653 0.347 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.653 0.347 0.000
N13 Obstructive and reflux uropathy
0.653 0.347 0.000
D32.1 Spinal meninges
0.651 0.348 0.000
I95.8 Other hypotension
0.651 0.348 0.000
I95.0 Idiopathic hypotension
0.651 0.348 0.000
S50-S59 Injuries to the elbow and forearm
0.651 0.349 0.000
M05 Seropositive rheumatoid arthritis
0.650 0.350 0.000
I09 Other rheumatic heart diseases
0.650 0.350 0.000
I06 Rheumatic aortic valve diseases
0.650 0.350 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.649 0.351 0.000
I50.1 Left ventricular failure
0.649 0.351 0.000
D06.9 Cervix, unspecified
0.648 0.352 0.000
I88 Nonspecific lymphadenitis
0.648 0.352 0.000
I82 Other venous embolism and thrombosis
0.648 0.352 0.000
I81 Portal vein thrombosis
0.648 0.352 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.647 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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