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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75397367
log Bayes Factor = 8.07931
Chromosome 16   position 84,041,217  (GRCh37) Explore rs75397367 on Ensembl!
Variant rs75397367 is part of Cluster X0188

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I44 Atrioventricular and left bundle-branch block
0.998 0.002 0.000
I49 Other cardiac arrhythmias
0.997 0.003 0.000
I35 Nonrheumatic aortic valve disorders
0.996 0.004 0.000
I05-I09 Chronic rheumatic heart diseases
0.992 0.008 0.000
I44.7 Left bundle-branch block, unspecified
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
I35.1 Aortic (valve) insufficiency
0.990 0.010 0.000
M50-M54 Other dorsopathies
0.988 0.012 0.000
M70-M79 Other soft tissue disorders
0.988 0.012 0.000
M51 Other intervertebral disk disorders
0.986 0.014 0.000
M79.6 Pain in limb
0.984 0.016 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.983 0.017 0.000
M51.2 Other specified intervertebral disk displacement
0.982 0.018 0.000
I49.8 Other specified cardiac arrhythmias
0.981 0.019 0.000
M79.66 Pain in limb (Lower leg)
0.981 0.019 0.000
Chapter I Certain infectious and parasitic diseases
0.978 0.022 0.000
I44.1 Atrioventricular block, second degree
0.972 0.028 0.000
I50 Heart failure
0.972 0.028 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.968 0.032 0.000
I05 Rheumatic mitral valve diseases
0.968 0.032 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.963 0.037 0.000
G62 Other polyneuropathies
0.961 0.039 0.000
I60-I69 Cerebrovascular diseases
0.961 0.039 0.000
I49.1 Atrial premature depolarisation
0.960 0.040 0.000
M40-M43 Deforming dorsopathies
0.958 0.042 0.000
M51.9 Intervertebral disk disorder, unspecified
0.955 0.045 0.000
M79.69 Pain in limb (Site unspecified)
0.954 0.046 0.000
M79.64 Pain in limb (Hand)
0.949 0.051 0.000
I42 Cardiomyopathy
0.948 0.052 0.000
G62.9 Polyneuropathy, unspecified
0.946 0.054 0.000
M20-M25 Other joint disorders
0.940 0.060 0.000
B35-B49 Mycoses
0.931 0.069 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.928 0.072 0.000
M41 Scoliosis
0.927 0.073 0.000
Chapter VIII Diseases of the ear and mastoid process
0.920 0.080 0.000
I50.1 Left ventricular failure
0.913 0.087 0.000
B37 Candidiasis
0.913 0.087 0.000
B37.9 Candidiasis, unspecified
0.911 0.089 0.000
Chapter XXII Codes for special purposes
0.903 0.097 0.000
I35.8 Other aortic valve disorders
0.903 0.097 0.000
I49.4 Other and unspecified premature depolarisation
0.902 0.098 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.896 0.104 0.000
I05.0 Mitral stenosis
0.896 0.104 0.000
M41.9 Scoliosis, unspecified
0.890 0.110 0.000
I50.0 Congestive heart failure
0.887 0.113 0.000
M34 Systemic sclerosis
0.881 0.119 0.000
I49.5 Sick sinus syndrome
0.879 0.121 0.000
I42.0 Dilated cardiomyopathy
0.874 0.126 0.000
M25 Other joint disorders, not elsewhere classified
0.871 0.129 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.859 0.141 0.000
H65-H75 Diseases of middle ear and mastoid
0.852 0.148 0.000
I07 Rheumatic tricuspid valve diseases
0.851 0.149 0.000
I05.1 Rheumatic mitral insufficiency
0.847 0.153 0.000
I69 Sequelae of cerebrovascular disease
0.843 0.157 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.842 0.158 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.842 0.158 0.000
I35.9 Aortic valve disorder, unspecified
0.842 0.158 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.837 0.163 0.000
M34.9 Systemic sclerosis, unspecified
0.835 0.165 0.000
M35 Other systemic involvement of connective tissue
0.834 0.166 0.000
I51 Complications and ill-defined descriptions of heart disease
0.834 0.166 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.832 0.168 0.000
M77 Other enthesopathies
0.831 0.169 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.828 0.172 0.000
B15-B19 Viral hepatitis
0.826 0.174 0.000
G35 Multiple sclerosis
0.825 0.175 0.000
M25.8 Other specified joint disorders
0.825 0.175 0.000
I67 Other cerebrovascular diseases
0.824 0.176 0.000
I44.4 Left anterior fascicular block
0.824 0.176 0.000
I63 Cerebral infarction
0.823 0.177 0.000
M60-M63 Disorders of muscles
0.817 0.183 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.816 0.184 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.816 0.184 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.815 0.185 0.000
I44.6 Other and unspecified fascicular block
0.814 0.186 0.000
I08 Multiple valve diseases
0.813 0.187 0.000
Q50-Q56 Congenital malformations of genital organs
0.813 0.187 0.000
G37 Other demyelinating diseases of central nervous system
0.812 0.188 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.808 0.192 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.806 0.194 0.000
M25.7 Osteophyte
0.806 0.194 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.806 0.194 0.000
M00-M03 Infectious arthropathies
0.805 0.195 0.000
I05.9 Mitral valve disease, unspecified
0.803 0.197 0.000
G62.0 Drug-induced polyneuropathy
0.801 0.199 0.000
H66 Suppurative and unspecified otitis media
0.800 0.200 0.000
I30 Acute pericarditis
0.798 0.202 0.000
I31 Other diseases of pericardium
0.798 0.202 0.000
I09 Other rheumatic heart diseases
0.792 0.208 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.792 0.208 0.000
I27 Other pulmonary heart diseases
0.791 0.209 0.000
S80-S89 Injuries to the knee and lower leg
0.790 0.210 0.000
G62.1 Alcoholic polyneuropathy
0.783 0.217 0.000
B95-B98 Bacterial, viral and other infectious agents
0.783 0.217 0.000
M79.9 Soft tissue disorder, unspecified
0.780 0.220 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.777 0.223 0.000
H71 Cholesteatoma of middle ear
0.777 0.223 0.000
M30 Polyarteritis nodosa and related conditions
0.773 0.227 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.772 0.228 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.771 0.229 0.000
S90-S99 Injuries to the ankle and foot
0.771 0.229 0.000
I61 Intracerebral haemorrhage
0.769 0.231 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.768 0.232 0.000
M41.8 Other forms of scoliosis
0.766 0.234 0.000
H66.9 Otitis media, unspecified
0.766 0.234 0.000
M25.86 Other specified joint disorders (Lower leg)
0.766 0.234 0.000
I42.2 Other hypertrophic cardiomyopathy
0.766 0.234 0.000
H90-H95 Other disorders of ear
0.764 0.236 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.764 0.236 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.764 0.236 0.000
G06.1 Intraspinal abscess and granuloma
0.764 0.236 0.000
M33 Dermatopolymyositis
0.760 0.240 0.000
H74 Other disorders of middle ear and mastoid
0.760 0.240 0.000
Q00-Q07 Congenital malformations of the nervous system
0.756 0.244 0.000
Q80-Q89 Other congenital malformations
0.756 0.244 0.000
S20-S29 Injuries to the thorax
0.755 0.245 0.000
I27.0 Primary pulmonary hypertension
0.754 0.246 0.000
I63.9 Cerebral infarction, unspecified
0.754 0.246 0.000
I07.1 Tricuspid insufficiency
0.750 0.250 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.746 0.254 0.000
I60 Subarachnoid haemorrhage
0.746 0.254 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.744 0.256 0.000
M80-M85 Disorders of bone density and structure
0.744 0.256 0.000
I37 Pulmonary valve disorders
0.743 0.257 0.000
A15-A19 Tuberculosis
0.743 0.257 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.743 0.257 0.000
L20-L30 Dermatitis and eczema
0.741 0.259 0.000
I42.6 Alcoholic cardiomyopathy
0.740 0.260 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.740 0.260 0.000
G62.8 Other specified polyneuropathies
0.739 0.260 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.739 0.261 0.000
M79.61 Pain in limb (Shoulder region)
0.739 0.261 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.739 0.261 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.739 0.261 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.738 0.262 0.000
Q60-Q64 Congenital malformations of the urinary system
0.738 0.262 0.000
Chapter XX External causes of morbidity and mortality
0.737 0.263 0.000
M79.60 Pain in limb (Multiple sites)
0.735 0.265 0.000
M51.4 Schmorl's nodes
0.734 0.266 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.733 0.267 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.733 0.267 0.000
U80 Agent resistant to penicillin and related antibiotics
0.732 0.268 0.000
G60 Hereditary and idiopathic neuropathy
0.732 0.268 0.000
I51.8 Other ill-defined heart diseases
0.732 0.268 0.000
I83 Varicose veins of lower extremities
0.732 0.268 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.731 0.269 0.000
B44 Aspergillosis
0.731 0.269 0.000
S22.4 Multiple fractures of ribs
0.729 0.271 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.729 0.271 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.728 0.272 0.000
I08.0 Disorders of both mitral and aortic valves
0.727 0.273 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.723 0.277 0.000
S22.40 Multiple fractures of ribs (closed)
0.720 0.280 0.000
M24 Other specific joint derangements
0.719 0.281 0.000
B17 Other acute viral hepatitis
0.719 0.281 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.718 0.282 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.717 0.283 0.000
M40 Kyphosis and lordosis
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I05.2 Mitral stenosis with insufficiency
0.717 0.283 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.715 0.285 0.000
Q24 Other congenital malformations of heart
0.715 0.285 0.000
I44.5 Left posterior fascicular block
0.715 0.285 0.000
I49.2 Junctional premature depolarisation
0.715 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.714 0.286 0.000
H74.4 Polyp of middle ear
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
I42.9 Cardiomyopathy, unspecified
0.712 0.288 0.000
I06 Rheumatic aortic valve diseases
0.711 0.289 0.000
I86 Varicose veins of other sites
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
I46 Cardiac arrest
0.711 0.289 0.000
G06.2 Extradural and subdural abscess, unspecified
0.709 0.291 0.000
T91 Sequelae of injuries of neck and trunk
0.709 0.291 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.708 0.292 0.000
M51.3 Other specified intervertebral disk degeneration
0.707 0.293 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.707 0.293 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.706 0.294 0.000
M79.68 Pain in limb (Other)
0.706 0.294 0.000
L40-L45 Papulosquamous disorders
0.706 0.294 0.000
M79.3 Panniculitis, unspecified
0.705 0.295 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.298 0.000
M76 Enthesopathies of lower limb, excluding foot
0.701 0.298 0.000
I31.9 Disease of pericardium, unspecified
0.701 0.298 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
S89 Other and unspecified injuries of lower leg
0.701 0.299 0.000
M35.1 Other overlap syndromes
0.697 0.303 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.696 0.304 0.000
I51.7 Cardiomegaly
0.696 0.304 0.000
M50 Cervical disk disorders
0.695 0.305 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.694 0.306 0.000
G64 Other disorders of peripheral nervous system
0.694 0.306 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.694 0.306 0.000
I05.8 Other mitral valve diseases
0.694 0.306 0.000
Chapter X Diseases of the respiratory system
0.693 0.307 0.000
I36 Nonrheumatic tricuspid valve disorders
0.693 0.307 0.000
M25.77 Osteophyte (Ankle and foot)
0.692 0.308 0.000
M35.0 Sicca syndrome [Sjogren]
0.691 0.309 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.691 0.309 0.000
Q35-Q37 Cleft lip and cleft palate
0.690 0.310 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.690 0.310 0.000
M71 Other bursopathies
0.690 0.310 0.000
G62.2 Polyneuropathy due to other toxic agents
0.689 0.311 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.689 0.311 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.689 0.311 0.000
H60-H62 Diseases of external ear
0.689 0.311 0.000
B36 Other superficial mycoses
0.687 0.313 0.000
B37.3 Candidiasis of vulva and vagina
0.687 0.313 0.000
M42 Spinal osteochondrosis
0.687 0.313 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.685 0.315 0.000
B50-B64 Protozoal diseases
0.684 0.316 0.000
M34.8 Other forms of systemic sclerosis
0.684 0.316 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.681 0.319 0.000
M77.4 Metatarsalgia
0.680 0.320 0.000
M79.1 Myalgia
0.680 0.320 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.679 0.320 0.000
I42.5 Other restrictive cardiomyopathy
0.679 0.320 0.000
I42.4 Endocardial fibroelastosis
0.679 0.320 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.679 0.320 0.000
S80 Superficial injury of lower leg
0.679 0.321 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.678 0.322 0.000
I30.9 Acute pericarditis, unspecified
0.678 0.322 0.000
M32 Systemic lupus erythematosus
0.678 0.322 0.000
B07 Viral warts
0.676 0.324 0.000
A30-A49 Other bacterial diseases
0.676 0.324 0.000
M79.0 Rheumatism, unspecified
0.675 0.325 0.000
J09-J18 Influenza and pneumonia
0.675 0.325 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.674 0.326 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.673 0.326 0.000
L27 Dermatitis due to substances taken internally
0.674 0.326 0.000
I38 Endocarditis, valve unspecified
0.673 0.327 0.000
M35.7 Hypermobility syndrome
0.672 0.328 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.671 0.329 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.670 0.330 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.670 0.330 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.669 0.331 0.000
G51 Facial nerve disorders
0.668 0.332 0.000
B48 Other mycoses, not elsewhere classified
0.668 0.332 0.000
B47 Mycetoma
0.668 0.332 0.000
B46 Zygomycosis
0.668 0.332 0.000
B45 Cryptococcosis
0.668 0.332 0.000
B43 Chromomycosis and phaeomycotic abscess
0.668 0.332 0.000
B42 Sporotrichosis
0.668 0.332 0.000
B41 Paracoccidioidomycosis
0.668 0.332 0.000
B40 Blastomycosis
0.668 0.332 0.000
B39 Histoplasmosis
0.668 0.332 0.000
B38 Coccidioidomycosis
0.668 0.332 0.000
M25.9 Joint disorder, unspecified
0.667 0.333 0.000
M80 Osteoporosis with pathological fracture
0.667 0.333 0.000
M43 Other deforming dorsopathies
0.667 0.333 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.666 0.334 0.000
M00 Pyogenic arthritis
0.666 0.334 0.000
M25.78 Osteophyte (Other)
0.666 0.334 0.000
G36 Other acute disseminated demyelination
0.665 0.335 0.000
M41.5 Other secondary scoliosis
0.664 0.335 0.000
M41.4 Neuromuscular scoliosis
0.664 0.335 0.000
M41.3 Thoracogenic scoliosis
0.664 0.335 0.000
M41.2 Other idiopathic scoliosis
0.664 0.335 0.000
M41.1 Juvenile idiopathic scoliosis
0.664 0.335 0.000
M41.0 Infantile idiopathic scoliosis
0.664 0.335 0.000
G11 Hereditary ataxia
0.663 0.337 0.000
I67.1 Cerebral aneurysm, nonruptured
0.663 0.337 0.000
G10 Huntington's disease
0.662 0.338 0.000
Q51 Congenital malformations of uterus and cervix
0.661 0.338 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.661 0.339 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.660 0.340 0.000
W00-W19 Falls
0.660 0.340 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.660 0.340 0.000
I33 Acute and subacute endocarditis
0.659 0.340 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.659 0.340 0.000
I50.9 Heart failure, unspecified
0.659 0.341 0.000
M72 Fibroblastic disorders
0.659 0.341 0.000
I86.1 Scrotal varices
0.659 0.341 0.000
B99-B99 Other infectious diseases
0.659 0.341 0.000
M60 Myositis
0.659 0.341 0.000
M31 Other necrotising vasculopathies
0.658 0.342 0.000
A00-A09 Intestinal infectious diseases
0.657 0.343 0.000
S10-S19 Injuries to the neck
0.657 0.343 0.000
B25-B34 Other viral diseases
0.656 0.344 0.000
S90 Superficial injury of ankle and foot
0.655 0.345 0.000
H92 Otalgia and effusion of ear
0.655 0.345 0.000
B37.7 Candidal septicaemia
0.655 0.345 0.000
B37.6 Candidal endocarditis
0.655 0.345 0.000
B37.5 Candidal meningitis
0.655 0.345 0.000
B37.2 Candidiasis of skin and nail
0.655 0.345 0.000
B37.1 Pulmonary candidiasis
0.655 0.345 0.000
U51 Admission status on psychiatric patients
0.654 0.346 0.000
I51.9 Heart disease, unspecified
0.653 0.347 0.000
M77.9 Enthesopathy, unspecified
0.651 0.349 0.000
G52 Disorders of other cranial nerves
0.651 0.349 0.000
M41.86 Other forms of scoliosis (Lumbar region)
0.651 0.349 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.651 0.349 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.651 0.349 0.000
G00 Bacterial meningitis, not elsewhere classified
0.650 0.350 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.649 0.351 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.649 0.351 0.000
I09.9 Rheumatic heart disease, unspecified
0.648 0.351 0.000
M79.63 Pain in limb (Forearm)
0.648 0.352 0.000
G50 Disorders of trigeminal nerve
0.648 0.352 0.000
I67.9 Cerebrovascular disease, unspecified
0.648 0.352 0.000
M70.2 Olecranon bursitis
0.647 0.353 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.647 0.353 0.000
M77.0 Medial epicondylitis
0.647 0.353 0.000
S92 Fracture of foot, except ankle
0.646 0.354 0.000
B19 Unspecified viral hepatitis
0.646 0.354 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.646 0.354 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.645 0.355 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.645 0.355 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.644 0.356 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.643 0.357 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.643 0.357 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.642 0.358 0.000
B17.1 Acute hepatitis C
0.642 0.358 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.642 0.358 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.641 0.359 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.638 0.362 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.638 0.362 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.638 0.362 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.638 0.362 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.638 0.362 0.000
S91 Open wound of ankle and foot
0.638 0.362 0.000
L40 Psoriasis
0.638 0.362 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.638 0.362 0.000
G30-G32 Other degenerative diseases of the nervous system
0.637 0.363 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.636 0.364 0.000
B16 Acute hepatitis B
0.635 0.364 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.635 0.365 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.634 0.365 0.000
Q61 Cystic kidney disease
0.634 0.366 0.000
G12 Spinal muscular atrophy and related syndromes
0.633 0.367 0.000
Q28 Other congenital malformations of circulatory system
0.633 0.367 0.000
G06.0 Intracranial abscess and granuloma
0.633 0.367 0.000
J11 Influenza, virus not identified
0.632 0.367 0.000
Y57 Other and unspecified drugs and medicaments
0.632 0.368 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.631 0.369 0.000
M34.0 Progressive systemic sclerosis
0.631 0.369 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.631 0.369 0.000
J00-J06 Acute upper respiratory infections
0.630 0.370 0.000
M86-M90 Other osteopathies
0.628 0.372 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.628 0.372 0.000
I46.9 Cardiac arrest, unspecified
0.627 0.372 0.000
W50-W64 Exposure to animate mechanical forces
0.627 0.373 0.000
M62 Other disorders of muscle
0.626 0.374 0.000
H60 Otitis externa
0.625 0.375 0.000
B00 Herpesviral [herpes simplex] infections
0.625 0.375 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.625 0.375 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.625 0.375 0.000
M05-M14 Inflammatory polyarthropathies
0.625 0.375 0.000
M25.2 Flail joint
0.624 0.375 0.000
M25.1 Fistula of joint
0.624 0.375 0.000
M50.2 Other cervical disk displacement
0.624 0.376 0.000
L28 Lichen simplex chronicus and prurigo
0.624 0.376 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.624 0.376 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.621 0.379 0.000
I27.9 Pulmonary heart disease, unspecified
0.621 0.379 0.000
G20-G26 Extrapyramidal and movement disorders
0.621 0.379 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.621 0.379 0.000
S86 Injury of muscle and tendon at lower leg level
0.620 0.380 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.619 0.381 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.619 0.381 0.000
L10-L14 Bullous disorders
0.617 0.383 0.000
W06 Fall involving bed
0.616 0.384 0.000
M99 Biomechanical lesions, not elsewhere classified
0.615 0.384 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.615 0.385 0.000
M79.67 Pain in limb (Ankle and foot)
0.614 0.386 0.000
S40-S49 Injuries to the shoulder and upper arm
0.614 0.386 0.000
J86 Pyothorax
0.614 0.386 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.614 0.386 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.613 0.387 0.000
S80.8 Other superficial injuries of lower leg
0.613 0.387 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.613 0.387 0.000
M33.1 Other dermatomyositis
0.612 0.388 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.612 0.388 0.000
M25.71 Osteophyte (Shoulder region)
0.612 0.388 0.000
T14 Injury of unspecified body region
0.612 0.388 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.611 0.389 0.000
Q55 Other congenital malformations of male genital organs
0.611 0.389 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.611 0.389 0.000
H68 Eustachian salpingitis and obstruction
0.611 0.389 0.000
H67 Otitis media in diseases classified elsewhere
0.611 0.389 0.000
I34 Nonrheumatic mitral valve disorders
0.611 0.389 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.610 0.390 0.000
I07.9 Tricuspid valve disease, unspecified
0.610 0.390 0.000
I07.8 Other tricuspid valve diseases
0.610 0.390 0.000
I07.2 Tricuspid stenosis with insufficiency
0.610 0.390 0.000
I07.0 Tricuspid stenosis
0.610 0.390 0.000
T79-T79 Certain early complications of trauma
0.610 0.390 0.000
M79.5 Residual foreign body in soft tissue
0.609 0.391 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.609 0.391 0.000
Q23 Congenital malformations of aortic and mitral valves
0.608 0.392 0.000
B44.1 Other pulmonary aspergillosis
0.606 0.394 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.606 0.394 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.606 0.394 0.000
I42.8 Other cardiomyopathies
0.605 0.395 0.000
J06.9 Acute upper respiratory infection, unspecified
0.605 0.395 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.604 0.396 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.604 0.396 0.000
H70 Mastoiditis and related conditions
0.604 0.396 0.000
I28 Other diseases of pulmonary vessels
0.604 0.396 0.000
I61.8 Other intracerebral haemorrhage
0.604 0.396 0.000
Q39 Congenital malformations of oesophagus
0.603 0.397 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.602 0.398 0.000
A49 Bacterial infection of unspecified site
0.602 0.398 0.000
M25.0 Haemarthrosis
0.602 0.398 0.000
S89.9 Unspecified injury of lower leg
0.602 0.398 0.000
M53 Other dorsopathies, not elsewhere classified
0.601 0.399 0.000
G82 Paraplegia and tetraplegia
0.601 0.399 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.600 0.400 0.000
G14 Postpolio syndrome
0.600 0.400 0.000
I77 Other disorders of arteries and arterioles
0.600 0.400 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.599 0.401 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.599 0.401 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.599 0.401 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.598 0.402 0.000
M35.8 Other specified systemic involvement of connective tissue
0.598 0.402 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.598 0.402 0.000
M35.5 Multifocal fibrosclerosis
0.598 0.402 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.598 0.402 0.000
M35.2 Behcet's disease
0.598 0.402 0.000
I51.5 Myocardial degeneration
0.598 0.402 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.598 0.402 0.000
Q24.8 Other specified congenital malformations of heart
0.598 0.402 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.597 0.403 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.596 0.404 0.000
M77.3 Calcaneal spur
0.596 0.404 0.000
M77.2 Periarthritis of wrist
0.596 0.404 0.000
L50-L54 Urticaria and erythema
0.596 0.404 0.000
S83.2 Tear of meniscus, current
0.596 0.404 0.000
T98 Sequelae of other and unspecified effects of external causes
0.594 0.406 0.000
M79.7 Fibromyalgia
0.594 0.406 0.000
I81 Portal vein thrombosis
0.594 0.406 0.000
S19 Other and unspecified injuries of neck
0.594 0.406 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.594 0.406 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.594 0.406 0.000
I62 Other nontraumatic intracranial haemorrhage
0.594 0.406 0.000
U50 Level of care administered to neonates
0.593 0.406 0.000
U07 Emergency use of U07
0.593 0.406 0.000
U06 Emergency use of U06
0.593 0.406 0.000
U04 Severe acute respiratory syndrome [SARS]
0.593 0.406 0.000
U52 First in a series of a regular day/night admissions
0.593 0.406 0.000
Q05 Spina bifida
0.593 0.406 0.000
Q43 Other congenital malformations of intestine
0.592 0.408 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.592 0.408 0.000
M25.88 Other specified joint disorders (Other)
0.592 0.408 0.000
M25.82 Other specified joint disorders (Upper arm)
0.592 0.408 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.592 0.408 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.591 0.409 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.591 0.409 0.000
I67.5 Moyamoya disease
0.591 0.409 0.000
I67.4 Hypertensive encephalopathy
0.591 0.409 0.000
I67.3 Progressive vascular leukoencephalopathy
0.591 0.409 0.000
M91-M94 Chondropathies
0.591 0.409 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.591 0.409 0.000
M51.8 Other specified intervertebral disk disorders
0.590 0.410 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.590 0.410 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.590 0.410 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.590 0.410 0.000
I27.2 Other secondary pulmonary hypertension
0.589 0.411 0.000
I44.3 Other and unspecified atrioventricular block
0.589 0.411 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.589 0.411 0.000
J86.9 Pyothorax without fistula
0.589 0.411 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.588 0.412 0.000
G72 Other myopathies
0.586 0.414 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.586 0.414 0.000
M61 Calcification and ossification of muscle
0.586 0.414 0.000
T91.1 Sequelae of fracture of spine
0.586 0.414 0.000
Q26 Congenital malformations of great veins
0.585 0.415 0.000
Q25 Congenital malformations of great arteries
0.585 0.415 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.585 0.415 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.585 0.415 0.000
Q27 Other congenital malformations of peripheral vascular system
0.585 0.415 0.000
B37.0 Candidal stomatitis
0.585 0.415 0.000
T33-T35 Frostbite
0.585 0.415 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.585 0.415 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.584 0.416 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.584 0.416 0.000
I08.9 Multiple valve disease, unspecified
0.583 0.417 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.583 0.417 0.000
Q52 Other congenital malformations of female genitalia
0.583 0.417 0.000
M34.1 CR(E)ST syndrome
0.583 0.417 0.000
L40.8 Other psoriasis
0.583 0.417 0.000
A08 Viral and other specified intestinal infections
0.583 0.417 0.000
B37.4 Candidiasis of other urogenital sites
0.583 0.417 0.000
G37.5 Concentric sclerosis [Balo]
0.582 0.417 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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