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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72781450
log Bayes Factor = 8.96513
Chromosome 16   position 13,988,334  (GRCh37) Explore rs72781450 on Ensembl!
Variant rs72781450 is part of Cluster X0188

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
O00-O08 Pregnancy with abortive outcome
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
M86-M90 Other osteopathies
0.996 0.004 0.000
M50-M54 Other dorsopathies
0.992 0.008 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.989 0.011 0.000
M54 Dorsalgia
0.985 0.015 0.000
M89 Other disorders of bone
0.981 0.019 0.000
M54.9 Dorsalgia, unspecified
0.980 0.020 0.000
I20-I25 Ischaemic heart diseases
0.979 0.021 0.000
I20 Angina pectoris
0.975 0.025 0.000
Y43 Primarily systemic agents
0.972 0.028 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.972 0.028 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.972 0.028 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
M89.9 Disorder of bone, unspecified
0.968 0.032 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.961 0.039 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.961 0.039 0.000
Chapter VI Diseases of the nervous system
0.953 0.047 0.000
Y43.3 Other antineoplastic drugs
0.953 0.047 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.950 0.050 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.948 0.052 0.000
I20.8 Other forms of angina pectoris
0.948 0.052 0.000
O02 Other abnormal products of conception
0.942 0.058 0.000
V10-V19 Pedal cyclist injured in transport accident
0.939 0.061 0.000
I05-I09 Chronic rheumatic heart diseases
0.936 0.064 0.000
M35 Other systemic involvement of connective tissue
0.917 0.083 0.000
I80 Phlebitis and thrombophlebitis
0.917 0.083 0.000
M54.2 Cervicalgia
0.913 0.087 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.912 0.088 0.000
O03 Spontaneous abortion
0.908 0.092 0.000
M87 Osteonecrosis
0.904 0.096 0.000
I20.0 Unstable angina
0.903 0.097 0.000
O02.1 Missed abortion
0.900 0.100 0.000
M40-M43 Deforming dorsopathies
0.898 0.102 0.000
O04 Medical abortion
0.896 0.104 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.893 0.107 0.000
Chapter X Diseases of the respiratory system
0.891 0.109 0.000
O41 Other disorders of amniotic fluid and membranes
0.890 0.110 0.000
M24 Other specific joint derangements
0.890 0.110 0.000
M34 Systemic sclerosis
0.888 0.112 0.000
T79-T79 Certain early complications of trauma
0.888 0.112 0.000
I82 Other venous embolism and thrombosis
0.882 0.118 0.000
T93 Sequelae of injuries of lower limb
0.882 0.118 0.000
I05 Rheumatic mitral valve diseases
0.880 0.120 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.877 0.123 0.000
Y52 Agents primarily affecting the cardiovascular system
0.875 0.125 0.000
M25 Other joint disorders, not elsewhere classified
0.873 0.127 0.000
O03.9 Complete or unspecified, without complication
0.870 0.130 0.000
I20.9 Angina pectoris, unspecified
0.870 0.130 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.870 0.130 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.867 0.133 0.000
V18.0 Driver injured in nontraffic accident
0.867 0.133 0.000
M35.3 Polymyalgia rheumatica
0.865 0.135 0.000
M45-M49 Spondylopathies
0.864 0.136 0.000
M54.22 Cervicalgia (Cervical region)
0.859 0.141 0.000
G90-G99 Other disorders of the nervous system
0.858 0.142 0.000
M80-M85 Disorders of bone density and structure
0.858 0.142 0.000
Chapter XXII Codes for special purposes
0.857 0.143 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.845 0.155 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.844 0.156 0.000
I30-I52 Other forms of heart disease
0.843 0.157 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.843 0.157 0.000
Q60-Q64 Congenital malformations of the urinary system
0.839 0.161 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.837 0.163 0.000
I86 Varicose veins of other sites
0.830 0.170 0.000
O41.0 Oligohydramnios
0.829 0.171 0.000
O04.9 Complete or unspecified, without complication
0.827 0.173 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.827 0.173 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.826 0.174 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.824 0.176 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.824 0.176 0.000
I05.9 Mitral valve disease, unspecified
0.823 0.177 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.822 0.178 0.000
I82.8 Embolism and thrombosis of other specified veins
0.821 0.179 0.000
I27 Other pulmonary heart diseases
0.819 0.180 0.000
O06 Unspecified abortion
0.818 0.182 0.000
M60-M63 Disorders of muscles
0.816 0.184 0.000
M43 Other deforming dorsopathies
0.816 0.184 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.812 0.188 0.000
S10-S19 Injuries to the neck
0.811 0.189 0.000
Y40 Systemic antibiotics
0.811 0.189 0.000
O00 Ectopic pregnancy
0.808 0.192 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.806 0.194 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.803 0.197 0.000
M86 Osteomyelitis
0.803 0.197 0.000
I51 Complications and ill-defined descriptions of heart disease
0.803 0.197 0.000
J30-J39 Other diseases of upper respiratory tract
0.800 0.200 0.000
M91-M94 Chondropathies
0.798 0.202 0.000
S32 Fracture of lumbar spine and pelvis
0.794 0.206 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.793 0.207 0.000
V80-V89 Other land transport accidents
0.793 0.207 0.000
J81 Pulmonary oedema
0.792 0.208 0.000
T93.2 Sequelae of other fractures of lower limb
0.792 0.208 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.790 0.209 0.000
M48 Other spondylopathies
0.790 0.210 0.000
O42 Premature rupture of membranes
0.790 0.210 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.790 0.210 0.000
M50 Cervical disk disorders
0.789 0.211 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.788 0.212 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.787 0.213 0.000
M34.9 Systemic sclerosis, unspecified
0.785 0.215 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.785 0.215 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.782 0.218 0.000
X50-X57 Overexertion, travel and privation
0.779 0.221 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.778 0.222 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.778 0.222 0.000
M32 Systemic lupus erythematosus
0.778 0.222 0.000
M87.2 Osteonecrosis due to previous trauma
0.775 0.224 0.000
M53 Other dorsopathies, not elsewhere classified
0.775 0.225 0.000
Y43.4 Immunosuppressive agents
0.775 0.225 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.774 0.226 0.000
O48 Prolonged pregnancy
0.773 0.227 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.773 0.227 0.000
M87.9 Osteonecrosis, unspecified
0.772 0.228 0.000
T79.8 Other early complications of trauma
0.771 0.229 0.000
J33 Nasal polyp
0.771 0.229 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.770 0.230 0.000
Q61 Cystic kidney disease
0.769 0.231 0.000
M89.8 Other specified disorders of bone
0.769 0.231 0.000
G93 Other disorders of brain
0.768 0.232 0.000
V40-V49 Car occupant injured in transport accident
0.768 0.232 0.000
O60-O75 Complications of labour and delivery
0.768 0.232 0.000
I08 Multiple valve diseases
0.768 0.232 0.000
Y52.1 Calcium-channel blockers
0.767 0.233 0.000
M05-M14 Inflammatory polyarthropathies
0.767 0.233 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.767 0.233 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.765 0.235 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.763 0.237 0.000
I45 Other conduction disorders
0.763 0.237 0.000
X60-X84 Intentional self-harm
0.762 0.238 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.760 0.240 0.000
G62 Other polyneuropathies
0.760 0.240 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.760 0.240 0.000
M89.98 Disorder of bone, unspecified (Other)
0.758 0.242 0.000
I49 Other cardiac arrhythmias
0.758 0.242 0.000
O85-O92 Complications predominantly related to the puerperium
0.756 0.244 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.755 0.245 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.754 0.246 0.000
M43.1 Spondylolisthesis
0.753 0.247 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.753 0.247 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.753 0.247 0.000
M24.2 Disorder of ligament
0.752 0.248 0.000
I81 Portal vein thrombosis
0.751 0.249 0.000
Q50-Q56 Congenital malformations of genital organs
0.750 0.249 0.000
I95 Hypotension
0.747 0.253 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.746 0.254 0.000
I27.2 Other secondary pulmonary hypertension
0.746 0.254 0.000
M34.1 CR(E)ST syndrome
0.745 0.255 0.000
T93.1 Sequelae of fracture of femur
0.744 0.256 0.000
M84 Disorders of continuity of bone
0.744 0.256 0.000
J20-J22 Other acute lower respiratory infections
0.741 0.258 0.000
T93.0 Sequelae of open wound of lower limb
0.741 0.259 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.739 0.260 0.000
Chapter I Certain infectious and parasitic diseases
0.739 0.261 0.000
Y43.1 Antineoplastic antimetabolites
0.736 0.263 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.736 0.264 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.736 0.264 0.000
I21 Acute myocardial infarction
0.736 0.264 0.000
G40-G47 Episodic and paroxysmal disorders
0.735 0.265 0.000
M00-M03 Infectious arthropathies
0.735 0.265 0.000
M65-M68 Disorders of synovium and tendon
0.734 0.266 0.000
M48.0 Spinal stenosis
0.733 0.267 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.732 0.268 0.000
O40 Polyhydramnios
0.731 0.269 0.000
M35.0 Sicca syndrome [Sjogren]
0.731 0.269 0.000
M46 Other inflammatory spondylopathies
0.731 0.269 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.729 0.271 0.000
J31.0 Chronic rhinitis
0.726 0.274 0.000
M88 Paget's disease of bone [osteitis deformans]
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.725 0.274 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.725 0.275 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.721 0.279 0.000
G62.9 Polyneuropathy, unspecified
0.720 0.280 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.719 0.281 0.000
J95-J99 Other diseases of the respiratory system
0.717 0.283 0.000
M54.3 Sciatica
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G93.0 Cerebral cysts
0.717 0.283 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.717 0.283 0.000
J33.8 Other polyp of sinus
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
O30 Multiple gestation
0.716 0.284 0.000
I22 Subsequent myocardial infarction
0.716 0.284 0.000
M21 Other acquired deformities of limbs
0.716 0.284 0.000
I51.7 Cardiomegaly
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.714 0.286 0.000
O07 Failed attempted abortion
0.714 0.286 0.000
O05 Other abortion
0.714 0.286 0.000
O01 Hydatidiform mole
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
M90 Osteopathies in diseases classified elsewhere
0.714 0.286 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.713 0.287 0.000
M54.6 Pain in thoracic spine
0.712 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.709 0.291 0.000
Y58 Bacterial vaccines
0.709 0.291 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.709 0.291 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.291 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.709 0.291 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.709 0.291 0.000
Y48 Anaesthetics and therapeutic gases
0.709 0.291 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.709 0.291 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.707 0.293 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.706 0.294 0.000
Y44 Agents primarily affecting blood constituents
0.706 0.294 0.000
I86.4 Gastric varices
0.706 0.294 0.000
M54.8 Other dorsalgia
0.706 0.294 0.000
M54.0 Panniculitis affecting regions of neck and back
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.705 0.295 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.704 0.295 0.000
M89.6 Osteopathy after poliomyelitis
0.704 0.296 0.000
M89.5 Osteolysis
0.704 0.296 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.704 0.296 0.000
M89.3 Hypertrophy of bone
0.704 0.296 0.000
M89.2 Other disorders of bone development and growth
0.704 0.296 0.000
M89.1 Epiphyseal arrest
0.704 0.296 0.000
M89.0 Algoneurodystrophy
0.704 0.296 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.702 0.297 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.702 0.298 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.702 0.298 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.702 0.298 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.702 0.298 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.702 0.298 0.000
I23 Certain current complications following acute myocardial infarction
0.702 0.298 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.702 0.298 0.000
I05.2 Mitral stenosis with insufficiency
0.702 0.298 0.000
G90 Disorders of autonomic nervous system
0.702 0.298 0.000
J33.0 Polyp of nasal cavity
0.701 0.299 0.000
I27.0 Primary pulmonary hypertension
0.699 0.301 0.000
Y43.9 Primarily systemic agent, unspecified
0.697 0.303 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.697 0.303 0.000
Y43.6 Enzymes, not elsewhere classified
0.697 0.303 0.000
Y43.5 Acidifying and alkalising agents
0.697 0.303 0.000
Y43.2 Antineoplastic natural products
0.697 0.303 0.000
Y43.0 Antiallergic and antiemetic drugs
0.697 0.303 0.000
O45 Premature separation of placenta [abruptio placentae]
0.697 0.303 0.000
O33 Maternal care for known or suspected disproportion
0.697 0.303 0.000
O31 Complications specific to multiple gestation
0.697 0.303 0.000
S32.0 Fracture of lumbar vertebra
0.696 0.304 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.696 0.304 0.000
Y42.7 Androgens and anabolic congeners
0.696 0.304 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.695 0.305 0.000
M33 Dermatopolymyositis
0.695 0.305 0.000
M30 Polyarteritis nodosa and related conditions
0.695 0.305 0.000
O36 Maternal care for other known or suspected foetal problems
0.695 0.305 0.000
I21.4 Acute subendocardial myocardial infarction
0.694 0.306 0.000
O20 Haemorrhage in early pregnancy
0.694 0.306 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.694 0.306 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.694 0.306 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.694 0.306 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.694 0.306 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.694 0.306 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.694 0.306 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.694 0.306 0.000
T00-T07 Injuries involving multiple body regions
0.694 0.306 0.000
T11 Other injuries of upper limb, level unspecified
0.693 0.306 0.000
M25.0 Haemarthrosis
0.693 0.307 0.000
Y85 Sequelae of transport accidents
0.692 0.308 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.692 0.308 0.000
I51.4 Myocarditis, unspecified
0.691 0.309 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.691 0.309 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.691 0.309 0.000
O06.9 Complete or unspecified, without complication
0.690 0.310 0.000
T66-T78 Other and unspecified effects of external causes
0.690 0.310 0.000
I36 Nonrheumatic tricuspid valve disorders
0.690 0.310 0.000
I88 Nonspecific lymphadenitis
0.689 0.311 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.689 0.311 0.000
Q35-Q37 Cleft lip and cleft palate
0.689 0.311 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.689 0.311 0.000
S50-S59 Injuries to the elbow and forearm
0.689 0.311 0.000
I47 Paroxysmal tachycardia
0.688 0.312 0.000
O00.1 Tubal pregnancy
0.688 0.312 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.686 0.314 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.685 0.314 0.000
G96 Other disorders of central nervous system
0.684 0.316 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.684 0.316 0.000
O44 Placenta praevia
0.683 0.317 0.000
G40 Epilepsy
0.683 0.317 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.683 0.317 0.000
S20-S29 Injuries to the thorax
0.682 0.318 0.000
M70-M79 Other soft tissue disorders
0.682 0.318 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
T33-T35 Frostbite
0.680 0.320 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.680 0.320 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.679 0.321 0.000
J00-J06 Acute upper respiratory infections
0.679 0.321 0.000
M84.0 Malunion of fracture
0.679 0.321 0.000
M50.1 Cervical disk disorder with radiculopathy
0.678 0.322 0.000
T98 Sequelae of other and unspecified effects of external causes
0.678 0.322 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.678 0.322 0.000
Q00-Q07 Congenital malformations of the nervous system
0.678 0.322 0.000
O02.9 Abnormal product of conception, unspecified
0.675 0.325 0.000
O02.8 Other specified abnormal products of conception
0.675 0.325 0.000
M25.3 Other instability of joint
0.674 0.326 0.000
M54.4 Lumbago with sciatica
0.673 0.326 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.673 0.326 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.673 0.326 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.673 0.326 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.673 0.326 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.673 0.326 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.673 0.326 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.673 0.326 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.673 0.326 0.000
M25.8 Other specified joint disorders
0.673 0.327 0.000
E10-E14 Diabetes mellitus
0.673 0.327 0.000
M41 Scoliosis
0.672 0.328 0.000
I51.0 Cardiac septal defect, acquired
0.672 0.328 0.000
I09 Other rheumatic heart diseases
0.671 0.329 0.000
I06 Rheumatic aortic valve diseases
0.671 0.329 0.000
M50.0 Cervical disk disorder with myelopathy
0.671 0.329 0.000
T79.6 Traumatic ischaemia of muscle
0.670 0.330 0.000
M82 Osteoporosis in diseases classified elsewhere
0.670 0.330 0.000
M25.4 Effusion of joint
0.670 0.330 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.670 0.330 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.669 0.331 0.000
O21 Excessive vomiting in pregnancy
0.669 0.331 0.000
M54.29 Cervicalgia-Site unspe
0.668 0.332 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.668 0.332 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.668 0.332 0.000
G82 Paraplegia and tetraplegia
0.668 0.332 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.666 0.334 0.000
M86.9 Osteomyelitis, unspecified
0.665 0.335 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.664 0.336 0.000
L40-L45 Papulosquamous disorders
0.664 0.336 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.663 0.337 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.663 0.337 0.000
M07 Psoriatic and enteropathic arthropathies
0.663 0.337 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.662 0.337 0.000
Chapter VIII Diseases of the ear and mastoid process
0.662 0.337 0.000
I34 Nonrheumatic mitral valve disorders
0.662 0.338 0.000
I95.2 Hypotension due to drugs
0.662 0.338 0.000
Q21 Congenital malformations of cardiac septa
0.662 0.338 0.000
T21 Burn and corrosion of trunk
0.661 0.339 0.000
I86.1 Scrotal varices
0.660 0.340 0.000
T90 Sequelae of injuries of head
0.660 0.340 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.658 0.342 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.658 0.342 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.658 0.342 0.000
M35.8 Other specified systemic involvement of connective tissue
0.658 0.342 0.000
M35.7 Hypermobility syndrome
0.658 0.342 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.658 0.342 0.000
M35.5 Multifocal fibrosclerosis
0.658 0.342 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.658 0.342 0.000
M35.2 Behcet's disease
0.658 0.342 0.000
M35.1 Other overlap syndromes
0.658 0.342 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.656 0.344 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.656 0.344 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.656 0.344 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.656 0.344 0.000
G44 Other headache syndromes
0.656 0.344 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.655 0.345 0.000
M54.27 Cervicalgia-Lumbosacral
0.655 0.345 0.000
M54.26 Cervicalgia-Lumbar
0.655 0.345 0.000
M54.25 Cervicalgia-Thoracolumbar
0.655 0.345 0.000
M54.24 Cervicalgia-Thoracic
0.655 0.345 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.655 0.345 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.655 0.345 0.000
M54.20 Cervicalgia-Mult site
0.655 0.345 0.000
I49.9 Cardiac arrhythmia, unspecified
0.655 0.345 0.000
T95 Sequelae of burns, corrosions and frostbite
0.654 0.346 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.654 0.346 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.654 0.346 0.000
Q43 Other congenital malformations of intestine
0.653 0.347 0.000
Q80-Q89 Other congenital malformations
0.652 0.347 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.651 0.349 0.000
O03.7 Complete or unspecified, complicated by embolism
0.651 0.349 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.651 0.349 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.651 0.349 0.000
O03.3 Incomplete, with other and unspecified complications
0.651 0.349 0.000
O03.2 Incomplete, complicated by embolism
0.651 0.349 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.651 0.349 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.651 0.349 0.000
M24.0 Loose body in joint
0.650 0.349 0.000
I83 Varicose veins of lower extremities
0.650 0.350 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.650 0.350 0.000
S70-S79 Injuries to the hip and thigh
0.650 0.350 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.650 0.350 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.649 0.351 0.000
M85 Other disorders of bone density and structure
0.649 0.351 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.648 0.352 0.000
M87.8 Other osteonecrosis
0.648 0.352 0.000
M87.3 Other secondary osteonecrosis
0.648 0.352 0.000
M87.1 Osteonecrosis due to drugs
0.648 0.352 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.648 0.352 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.648 0.352 0.000
E14 Unspecified diabetes mellitus
0.647 0.353 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.646 0.354 0.000
I24 Other acute ischaemic heart diseases
0.646 0.354 0.000
I49.5 Sick sinus syndrome
0.645 0.355 0.000
O61 Failed induction of labour
0.645 0.355 0.000
M48.09 Spinal stenosis (Site unspecified)
0.645 0.355 0.000
M42 Spinal osteochondrosis
0.644 0.356 0.000
M40 Kyphosis and lordosis
0.644 0.356 0.000
Q28 Other congenital malformations of circulatory system
0.644 0.356 0.000
M62 Other disorders of muscle
0.643 0.356 0.000
B35-B49 Mycoses
0.643 0.357 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.643 0.357 0.000
Q61.3 Polycystic kidney, unspecified
0.643 0.357 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.643 0.357 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.643 0.357 0.000
O04.7 Complete or unspecified, complicated by embolism
0.643 0.357 0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.643 0.357 0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.643 0.357 0.000
O04.3 Incomplete, with other and unspecified complications
0.643 0.357 0.000
O04.2 Incomplete, complicated by embolism
0.643 0.357 0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.643 0.357 0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.643 0.357 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.642 0.358 0.000
G61 Inflammatory polyneuropathy
0.642 0.358 0.000
M24.1 Other articular cartilage disorders
0.642 0.358 0.000
I49.4 Other and unspecified premature depolarisation
0.642 0.358 0.000
I37 Pulmonary valve disorders
0.641 0.359 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.640 0.359 0.000
V18.4 Driver injured in traffic accident
0.640 0.359 0.000
V18.5 Passenger injured in traffic accident
0.640 0.359 0.000
V18.3 Person injured while boarding or alighting
0.640 0.359 0.000
V18.1 Passenger injured in nontraffic accident
0.640 0.359 0.000
M60 Myositis
0.640 0.359 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.640 0.360 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.640 0.360 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.640 0.360 0.000
I45.1 Other and unspecified right bundle-branch block
0.639 0.361 0.000
Y40.3 Macrolides
0.639 0.361 0.000
T23 Burn and corrosion of wrist and hand
0.639 0.361 0.000
M92 Other juvenile osteochondrosis
0.639 0.361 0.000
T94.1 Sequelae of injuries, not specified by body region
0.638 0.361 0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified
0.638 0.362 0.000
O41.1 Infection of amniotic sac and membranes
0.638 0.362 0.000
M24.9 Joint derangement, unspecified
0.638 0.362 0.000
M24.7 Protrusio acetabuli
0.638 0.362 0.000
M24.6 Ankylosis of joint
0.638 0.362 0.000
M24.5 Contracture of joint
0.638 0.362 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.638 0.362 0.000
T13 Other injuries of lower limb, level unspecified
0.638 0.362 0.000
M25.9 Joint disorder, unspecified
0.638 0.362 0.000
M51 Other intervertebral disk disorders
0.638 0.362 0.000
M34.8 Other forms of systemic sclerosis
0.637 0.363 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.637 0.363 0.000
M34.0 Progressive systemic sclerosis
0.637 0.363 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.636 0.364 0.000
O04.4 Incomplete, without complication
0.636 0.364 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.636 0.364 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.635 0.365 0.000
J22 Unspecified acute lower respiratory infection
0.635 0.365 0.000
I05.0 Mitral stenosis
0.634 0.366 0.000
T14 Injury of unspecified body region
0.634 0.366 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.634 0.366 0.000
G83 Other paralytic syndromes
0.633 0.367 0.000
I82.3 Embolism and thrombosis of renal vein
0.633 0.367 0.000
I82.2 Embolism and thrombosis of vena cava
0.633 0.367 0.000
I82.1 Thrombophlebitis migrans
0.633 0.367 0.000
I82.0 Budd-Chiari syndrome
0.633 0.367 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.632 0.368 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.632 0.368 0.000
I95.1 Orthostatic hypotension
0.632 0.368 0.000
I05.8 Other mitral valve diseases
0.631 0.369 0.000
I05.1 Rheumatic mitral insufficiency
0.631 0.369 0.000
I51.6 Cardiovascular disease, unspecified
0.631 0.369 0.000
M48.02 Spinal stenosis (Cervical region)
0.630 0.370 0.000
A30-A49 Other bacterial diseases
0.630 0.370 0.000
Q61.2 Polycystic kidney, adult type
0.630 0.370 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.629 0.371 0.000
S37 Injury of urinary and pelvic organs
0.629 0.371 0.000
S36 Injury of intra-abdominal organs
0.629 0.371 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.629 0.371 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.629 0.371 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.629 0.371 0.000
S31 Open wound of abdomen, lower back and pelvis
0.629 0.371 0.000
J32 Chronic sinusitis
0.629 0.371 0.000
E40-E46 Malnutrition
0.628 0.372 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.627 0.373 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.627 0.373 0.000
Y52.7 Peripheral vasodilators
0.627 0.373 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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