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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117151396
log Bayes Factor = 15.1715
Chromosome 20   position 17,934,882  (GRCh37) Explore rs117151396 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.991 0.009 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
I05-I09 Chronic rheumatic heart diseases
0.985 0.015 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.985 0.015 0.000
D00-D09 In situ neoplasms
0.977 0.023 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.977 0.023 0.000
E89.0 Postprocedural hypothyroidism
0.973 0.027 0.000
C51-C58 Malignant neoplasms of female genital organs
0.973 0.027 0.000
J40-J47 Chronic lower respiratory diseases
0.971 0.029 0.000
Chapter XX External causes of morbidity and mortality
0.970 0.030 0.000
I50 Heart failure
0.970 0.030 0.000
G40-G47 Episodic and paroxysmal disorders
0.968 0.032 0.000
J90-J94 Other diseases of pleura
0.965 0.035 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.965 0.035 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.964 0.036 0.000
J44 Other chronic obstructive pulmonary disease
0.963 0.037 0.000
E20-E35 Disorders of other endocrine glands
0.962 0.038 0.000
D05 Carcinoma in situ of breast
0.962 0.038 0.000
I05 Rheumatic mitral valve diseases
0.956 0.044 0.000
E00-E07 Disorders of thyroid gland
0.955 0.045 0.000
D05.1 Intraductal carcinoma in situ
0.954 0.046 0.000
E86 Volume depletion
0.951 0.049 0.000
C77.3 Axillary and upper limb lymph nodes
0.944 0.056 0.000
C79 Secondary malignant neoplasm of other sites
0.942 0.058 0.000
C50-C50 Malignant neoplasm of breast
0.935 0.065 0.000
C64-C68 Malignant neoplasms of urinary tract
0.933 0.067 0.000
C77.2 Intra-abdominal lymph nodes
0.932 0.068 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.929 0.071 0.000
I50.1 Left ventricular failure
0.925 0.075 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.924 0.076 0.000
G40 Epilepsy
0.921 0.079 0.000
E83 Disorders of mineral metabolism
0.921 0.079 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.916 0.084 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.915 0.085 0.000
Chapter XXI Factors influencing health status and contact with health services
0.913 0.087 0.000
I34 Nonrheumatic mitral valve disorders
0.913 0.087 0.000
C78.7 Secondary malignant neoplasm of liver
0.913 0.087 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.910 0.090 0.000
I95 Hypotension
0.905 0.095 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.903 0.097 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.903 0.097 0.000
C15-C26 Malignant neoplasms of digestive organs
0.902 0.098 0.000
G90-G99 Other disorders of the nervous system
0.900 0.100 0.000
Chapter I Certain infectious and parasitic diseases
0.899 0.101 0.000
G47 Sleep disorders
0.898 0.102 0.000
J84 Other interstitial pulmonary diseases
0.894 0.106 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.893 0.107 0.000
J95-J99 Other diseases of the respiratory system
0.892 0.108 0.000
C50 Malignant neoplasm of breast
0.889 0.111 0.000
E50-E64 Other nutritional deficiencies
0.887 0.113 0.000
J30-J39 Other diseases of upper respiratory tract
0.887 0.113 0.000
C54 Malignant neoplasm of corpus uteri
0.882 0.118 0.000
J34 Other disorders of nose and nasal sinuses
0.880 0.120 0.000
J90 Pleural effusion, not elsewhere classified
0.880 0.120 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.876 0.124 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.876 0.124 0.000
I05.0 Mitral stenosis
0.874 0.126 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.873 0.127 0.000
I47 Paroxysmal tachycardia
0.873 0.127 0.000
Y43 Primarily systemic agents
0.873 0.127 0.000
I60-I69 Cerebrovascular diseases
0.873 0.127 0.000
I95.9 Hypotension, unspecified
0.871 0.129 0.000
I08 Multiple valve diseases
0.869 0.131 0.000
I50.0 Congestive heart failure
0.868 0.132 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.868 0.132 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.867 0.133 0.000
C50.9 Breast, unspecified
0.866 0.134 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.864 0.136 0.000
C77.5 Intrapelvic lymph nodes
0.862 0.138 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.856 0.144 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.855 0.145 0.000
I99 Other and unspecified disorders of circulatory system
0.855 0.145 0.000
G20-G26 Extrapyramidal and movement disorders
0.854 0.146 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.854 0.146 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.852 0.148 0.000
B95-B98 Bacterial, viral and other infectious agents
0.850 0.150 0.000
J81 Pulmonary oedema
0.849 0.151 0.000
I44 Atrioventricular and left bundle-branch block
0.848 0.152 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.848 0.152 0.000
I27 Other pulmonary heart diseases
0.848 0.152 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.845 0.155 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.845 0.155 0.000
J20-J22 Other acute lower respiratory infections
0.843 0.157 0.000
I05.9 Mitral valve disease, unspecified
0.842 0.158 0.000
Z60 Problems related to social environment
0.840 0.160 0.000
E53 Deficiency of other B group vitamins
0.836 0.164 0.000
E05.9 Thyrotoxicosis, unspecified
0.835 0.165 0.000
E83.5 Disorders of calcium metabolism
0.835 0.165 0.000
C53 Malignant neoplasm of cervix uteri
0.834 0.166 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.830 0.170 0.000
Y43.3 Other antineoplastic drugs
0.829 0.171 0.000
Z98 Other postsurgical states
0.828 0.172 0.000
J92 Pleural plaque
0.827 0.173 0.000
Z92 Personal history of medical treatment
0.825 0.175 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
I84 Haemorrhoids
0.824 0.176 0.000
Z98.0 Intestinal bypass and anastomosis status
0.824 0.176 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.824 0.176 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.820 0.180 0.000
I67 Other cerebrovascular diseases
0.820 0.180 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.820 0.180 0.000
J98 Other respiratory disorders
0.818 0.182 0.000
C54.1 Endometrium
0.818 0.182 0.000
G47.9 Sleep disorder, unspecified
0.818 0.182 0.000
I34.1 Mitral (valve) prolapse
0.817 0.183 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.817 0.183 0.000
Z60.2 Living alone
0.814 0.186 0.000
J94 Other pleural conditions
0.812 0.188 0.000
E07 Other disorders of thyroid
0.810 0.190 0.000
C78.2 Secondary malignant neoplasm of pleura
0.810 0.190 0.000
C77.4 Inguinal and lower limb lymph nodes
0.808 0.192 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.808 0.192 0.000
T92 Sequelae of injuries of upper limb
0.808 0.192 0.000
I47.1 Supraventricular tachycardia
0.806 0.194 0.000
E21.3 Hyperparathyroidism, unspecified
0.805 0.195 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.804 0.196 0.000
J34.2 Deviated nasal septum
0.803 0.197 0.000
E87.2 Acidosis
0.803 0.197 0.000
E53.8 Deficiency of other specified B group vitamins
0.800 0.200 0.000
C77.1 Intrathoracic lymph nodes
0.798 0.202 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.797 0.203 0.000
I05.2 Mitral stenosis with insufficiency
0.795 0.205 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.792 0.208 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.791 0.209 0.000
G25 Other extrapyramidal and movement disorders
0.790 0.210 0.000
S50-S59 Injuries to the elbow and forearm
0.789 0.211 0.000
D04 Carcinoma in situ of skin
0.785 0.215 0.000
J09-J18 Influenza and pneumonia
0.783 0.217 0.000
Z90.1 Acquired absence of breast(s)
0.783 0.217 0.000
I27.0 Primary pulmonary hypertension
0.782 0.218 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.780 0.220 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.778 0.222 0.000
G30-G32 Other degenerative diseases of the nervous system
0.777 0.223 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.777 0.223 0.000
C50.4 Upper-outer quadrant of breast
0.777 0.223 0.000
E27 Other disorders of adrenal gland
0.775 0.225 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.774 0.226 0.000
D05.0 Lobular carcinoma in situ
0.772 0.228 0.000
I84.6 Residual haemorrhoidal skin tags
0.771 0.229 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.770 0.230 0.000
I30 Acute pericarditis
0.770 0.230 0.000
J42 Unspecified chronic bronchitis
0.770 0.230 0.000
E28 Ovarian dysfunction
0.769 0.231 0.000
C79.2 Secondary malignant neoplasm of skin
0.769 0.231 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.769 0.231 0.000
E83.4 Disorders of magnesium metabolism
0.767 0.233 0.000
C34 Malignant neoplasm of bronchus and lung
0.767 0.233 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.766 0.233 0.000
I67.8 Other specified cerebrovascular diseases
0.764 0.236 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.764 0.236 0.000
E21.0 Primary hyperparathyroidism
0.762 0.238 0.000
G40.9 Epilepsy, unspecified
0.760 0.240 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.760 0.240 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.759 0.241 0.000
J34.3 Hypertrophy of nasal turbinates
0.759 0.241 0.000
V40-V49 Car occupant injured in transport accident
0.757 0.243 0.000
I44.0 Atrioventricular block, first degree
0.756 0.244 0.000
I38 Endocarditis, valve unspecified
0.755 0.244 0.000
G44 Other headache syndromes
0.755 0.245 0.000
I84.1 Internal haemorrhoids with other complications
0.755 0.245 0.000
J43 Emphysema
0.753 0.247 0.000
E89.2 Postprocedural hypoparathyroidism
0.753 0.247 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.752 0.248 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.750 0.250 0.000
C51 Malignant neoplasm of vulva
0.750 0.250 0.000
Z93 Artificial opening status
0.749 0.251 0.000
E83.3 Disorders of phosphorus metabolism
0.748 0.252 0.000
J98.4 Other disorders of lung
0.745 0.255 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.743 0.257 0.000
D09 Carcinoma in situ of other and unspecified sites
0.741 0.259 0.000
G93 Other disorders of brain
0.741 0.259 0.000
I50.9 Heart failure, unspecified
0.739 0.261 0.000
J80 Adult respiratory distress syndrome
0.739 0.261 0.000
E40-E46 Malnutrition
0.738 0.262 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.738 0.262 0.000
C09 Malignant neoplasm of tonsil
0.737 0.263 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.736 0.264 0.000
V80-V89 Other land transport accidents
0.734 0.266 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
C53.9 Cervix uteri, unspecified
0.734 0.266 0.000
J91 Pleural effusion in conditions classified elsewhere
0.733 0.267 0.000
I07 Rheumatic tricuspid valve diseases
0.732 0.268 0.000
Y84.8 Other medical procedures
0.732 0.268 0.000
E34 Other endocrine disorders
0.731 0.269 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.730 0.270 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.728 0.272 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.728 0.272 0.000
S10-S19 Injuries to the neck
0.728 0.272 0.000
I27.2 Other secondary pulmonary hypertension
0.727 0.273 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.273 0.000
I33 Acute and subacute endocarditis
0.724 0.276 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.723 0.277 0.000
B99-B99 Other infectious diseases
0.722 0.278 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.720 0.280 0.000
E04 Other non-toxic goitre
0.719 0.281 0.000
T92.1 Sequelae of fracture of arm
0.719 0.281 0.000
W50-W64 Exposure to animate mechanical forces
0.718 0.282 0.000
C17 Malignant neoplasm of small intestine
0.717 0.283 0.000
I49 Other cardiac arrhythmias
0.717 0.283 0.000
T81 Complications of procedures, not elsewhere classified
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
G90 Disorders of autonomic nervous system
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C15 Malignant neoplasm of oesophagus
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.286 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.713 0.287 0.000
J92.9 Pleural plaque without asbestos
0.711 0.289 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.710 0.290 0.000
Y40 Systemic antibiotics
0.710 0.290 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.710 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I34.0 Mitral (valve) insufficiency
0.709 0.291 0.000
S80-S89 Injuries to the knee and lower leg
0.707 0.293 0.000
E07.9 Disorder of thyroid, unspecified
0.706 0.293 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.706 0.294 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.706 0.294 0.000
I09 Other rheumatic heart diseases
0.706 0.294 0.000
I06 Rheumatic aortic valve diseases
0.706 0.294 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.706 0.294 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.706 0.294 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.706 0.294 0.000
E89.5 Postprocedural testicular hypofunction
0.706 0.294 0.000
E89.4 Postprocedural ovarian failure
0.706 0.294 0.000
E89.3 Postprocedural hypopituitarism
0.706 0.294 0.000
E89.1 Postprocedural hypoinsulinaemia
0.706 0.294 0.000
C56 Malignant neoplasm of ovary
0.706 0.294 0.000
E06 Thyroiditis
0.705 0.294 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.703 0.297 0.000
S90-S99 Injuries to the ankle and foot
0.702 0.298 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.702 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.701 0.299 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.701 0.299 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.701 0.299 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.701 0.299 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.701 0.299 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.701 0.299 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.701 0.299 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.701 0.299 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.701 0.299 0.000
Z80 Family history of malignant neoplasm
0.701 0.299 0.000
I67.9 Cerebrovascular disease, unspecified
0.700 0.300 0.000
G61 Inflammatory polyneuropathy
0.699 0.301 0.000
G41 Status epilepticus
0.699 0.301 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.699 0.301 0.000
C34.3 Lower lobe, bronchus or lung
0.699 0.301 0.000
Z90.2 Acquired absence of lung [part of]
0.698 0.302 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.697 0.303 0.000
C58 Malignant neoplasm of placenta
0.697 0.303 0.000
C52 Malignant neoplasm of vagina
0.697 0.303 0.000
J41 Simple and mucopurulent chronic bronchitis
0.696 0.304 0.000
J22 Unspecified acute lower respiratory infection
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
Y00-Y09 Assault
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.304 0.000
X50-X57 Overexertion, travel and privation
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.694 0.306 0.000
J35 Chronic diseases of tonsils and adenoids
0.694 0.306 0.000
G96 Other disorders of central nervous system
0.693 0.307 0.000
S56 Injury of muscle and tendon at forearm level
0.693 0.307 0.000
I63 Cerebral infarction
0.693 0.307 0.000
A80-A89 Viral infections of the central nervous system
0.693 0.307 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.693 0.307 0.000
Z63 Other problems related to primary support group, including family circumstances
0.693 0.307 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.692 0.308 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.692 0.308 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.691 0.309 0.000
B35-B49 Mycoses
0.690 0.310 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.690 0.310 0.000
E32 Diseases of thymus
0.690 0.310 0.000
E31 Polyglandular dysfunction
0.690 0.310 0.000
E30 Disorders of puberty, not elsewhere classified
0.690 0.310 0.000
E26 Hyperaldosteronism
0.690 0.310 0.000
E25 Adrenogenital disorders
0.690 0.310 0.000
E24 Cushing's syndrome
0.690 0.310 0.000
E20 Hypoparathyroidism
0.690 0.310 0.000
D05.7 Other carcinoma in situ of breast
0.690 0.310 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.690 0.310 0.000
E87.0 Hyperosmolality and hypernatraemia
0.689 0.311 0.000
C16 Malignant neoplasm of stomach
0.688 0.312 0.000
I05.8 Other mitral valve diseases
0.686 0.314 0.000
I05.1 Rheumatic mitral insufficiency
0.686 0.314 0.000
Y42.5 Other oestrogens and progestogens
0.685 0.315 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.684 0.315 0.000
E00 Congenital iodine-deficiency syndrome
0.684 0.315 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.684 0.315 0.000
T79-T79 Certain early complications of trauma
0.684 0.316 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.684 0.316 0.000
I86 Varicose veins of other sites
0.684 0.316 0.000
J30 Vasomotor and allergic rhinitis
0.683 0.317 0.000
I84.9 Unspecified haemorrhoids without complication
0.681 0.319 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.681 0.319 0.000
Y57 Other and unspecified drugs and medicaments
0.681 0.319 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.680 0.320 0.000
E29 Testicular dysfunction
0.679 0.321 0.000
I44.2 Atrioventricular block, complete
0.678 0.322 0.000
T91 Sequelae of injuries of neck and trunk
0.678 0.322 0.000
Y84.2 Radiological procedure and radiotherapy
0.678 0.322 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.677 0.323 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.677 0.323 0.000
B15-B19 Viral hepatitis
0.676 0.324 0.000
C21 Malignant neoplasm of anus and anal canal
0.676 0.324 0.000
C79.6 Secondary malignant neoplasm of ovary
0.675 0.325 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.675 0.325 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.675 0.325 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.674 0.325 0.000
C77.8 Lymph nodes of multiple regions
0.672 0.327 0.000
Z30 Contraceptive management
0.670 0.330 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.669 0.330 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.669 0.331 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.669 0.331 0.000
C66 Malignant neoplasm of ureter
0.669 0.331 0.000
C65 Malignant neoplasm of renal pelvis
0.669 0.331 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.668 0.332 0.000
J94.1 Fibrothorax
0.668 0.332 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.668 0.332 0.000
I45 Other conduction disorders
0.667 0.332 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.667 0.333 0.000
T33-T35 Frostbite
0.666 0.334 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.666 0.334 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.666 0.334 0.000
T00-T07 Injuries involving multiple body regions
0.666 0.334 0.000
E22 Hyperfunction of pituitary gland
0.665 0.335 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.664 0.336 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.663 0.337 0.000
X60-X84 Intentional self-harm
0.663 0.337 0.000
E23 Hypofunction and other disorders of pituitary gland
0.663 0.337 0.000
Y43.1 Antineoplastic antimetabolites
0.662 0.337 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.662 0.338 0.000
Y59 Other and unspecified vaccines and biological substances
0.662 0.338 0.000
Y58 Bacterial vaccines
0.662 0.338 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.662 0.338 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.662 0.338 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.662 0.338 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.662 0.338 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.662 0.338 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.662 0.338 0.000
Y48 Anaesthetics and therapeutic gases
0.662 0.338 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.662 0.338 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.662 0.338 0.000
Z92.3 Personal history of irradiation
0.662 0.338 0.000
J20 Acute bronchitis
0.661 0.338 0.000
S20-S29 Injuries to the thorax
0.661 0.339 0.000
G40.8 Other epilepsy
0.660 0.340 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.660 0.340 0.000
G40.5 Special epileptic syndromes
0.660 0.340 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.660 0.340 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.660 0.340 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.660 0.340 0.000
E83.8 Other disorders of mineral metabolism
0.660 0.340 0.000
E83.2 Disorders of zinc metabolism
0.660 0.340 0.000
E83.0 Disorders of copper metabolism
0.660 0.340 0.000
J47 Bronchiectasis
0.660 0.340 0.000
Z30.2 Sterilisation
0.658 0.342 0.000
G91 Hydrocephalus
0.658 0.342 0.000
D04.2 Skin of ear and external auricular canal
0.658 0.342 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.657 0.342 0.000
Z93.6 Other artificial openings of urinary tract status
0.657 0.343 0.000
E05.8 Other thyrotoxicosis
0.657 0.343 0.000
E05.5 Thyroid crisis or storm
0.657 0.343 0.000
E05.4 Thyrotoxicosis factitia
0.657 0.343 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.657 0.343 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.657 0.343 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.657 0.343 0.000
C20 Malignant neoplasm of rectum
0.657 0.343 0.000
D80-D89 Certain disorders involving the immune mechanism
0.657 0.343 0.000
Z90.5 Acquired absence of kidney
0.657 0.343 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.655 0.345 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.655 0.345 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.655 0.345 0.000
J98.6 Disorders of diaphragm
0.654 0.346 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.654 0.346 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.654 0.346 0.000
E87.7 Fluid overload
0.653 0.346 0.000
I31 Other diseases of pericardium
0.653 0.347 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.653 0.347 0.000
E21.4 Other specified disorders of parathyroid gland
0.653 0.347 0.000
E21.2 Other hyperparathyroidism
0.653 0.347 0.000
C18 Malignant neoplasm of colon
0.652 0.348 0.000
T66-T78 Other and unspecified effects of external causes
0.652 0.348 0.000
C09.9 Tonsil, unspecified
0.652 0.348 0.000
V20-V29 Motorcycle rider injured in transport accident
0.650 0.349 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.651 0.349 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.651 0.349 0.000
I69 Sequelae of cerebrovascular disease
0.650 0.350 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.650 0.350 0.000
G93.4 Encephalopathy, unspecified
0.650 0.350 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.649 0.350 0.000
I95.8 Other hypotension
0.649 0.351 0.000
I95.0 Idiopathic hypotension
0.649 0.351 0.000
C50.1 Central portion of breast
0.648 0.352 0.000
Q80-Q89 Other congenital malformations
0.647 0.353 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.647 0.353 0.000
C23 Malignant neoplasm of gallbladder
0.647 0.353 0.000
I95.1 Orthostatic hypotension
0.647 0.353 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.646 0.353 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.646 0.353 0.000
I44.6 Other and unspecified fascicular block
0.646 0.354 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.646 0.354 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.645 0.355 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.645 0.355 0.000
G92 Toxic encephalopathy
0.645 0.355 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.645 0.355 0.000
B65-B83 Helminthiases
0.645 0.355 0.000
B50-B64 Protozoal diseases
0.645 0.355 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.645 0.355 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.645 0.355 0.000
A75-A79 Rickettsioses
0.645 0.355 0.000
A70-A74 Other diseases caused by chlamydiae
0.645 0.355 0.000
A65-A69 Other spirochaetal diseases
0.645 0.355 0.000
A20-A28 Certain zoonotic bacterial diseases
0.645 0.355 0.000
A15-A19 Tuberculosis
0.645 0.355 0.000
I84.5 External haemorrhoids without complication
0.644 0.356 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.644 0.356 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.644 0.356 0.000
G47.8 Other sleep disorders
0.644 0.356 0.000
G47.4 Narcolepsy and cataplexy
0.644 0.356 0.000
G47.2 Disorders of the sleep-wake schedule
0.644 0.356 0.000
J46 Status asthmaticus
0.643 0.357 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.643 0.357 0.000
Y52 Agents primarily affecting the cardiovascular system
0.641 0.359 0.000
J84.8 Other specified interstitial pulmonary diseases
0.641 0.359 0.000
J84.0 Alveolar and parietoalveolar conditions
0.641 0.359 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.641 0.359 0.000
E88 Other metabolic disorders
0.641 0.359 0.000
I28 Other diseases of pulmonary vessels
0.640 0.359 0.000
D06 Carcinoma in situ of cervix uteri
0.640 0.360 0.000
Y95 Nosocomial condition
0.640 0.360 0.000
J96 Respiratory failure, not elsewhere classified
0.640 0.360 0.000
J17 Pneumonia in diseases classified elsewhere
0.639 0.361 0.000
I74 Arterial embolism and thrombosis
0.639 0.361 0.000
J93 Pneumothorax
0.638 0.362 0.000
C50.6 Axillary tail of breast
0.637 0.363 0.000
I87 Other disorders of veins
0.637 0.363 0.000
J94.2 Haemothorax
0.637 0.363 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.636 0.364 0.000
E63 Other nutritional deficiencies
0.636 0.364 0.000
E56 Other vitamin deficiencies
0.636 0.364 0.000
E51 Thiamine deficiency
0.636 0.364 0.000
E50 Vitamin A deficiency
0.636 0.364 0.000
E60 Dietary zinc deficiency
0.636 0.364 0.000
E59 Dietary selenium deficiency
0.636 0.364 0.000
E58 Dietary calcium deficiency
0.636 0.364 0.000
E54 Ascorbic acid deficiency
0.636 0.364 0.000
E52 Niacin deficiency [pellagra]
0.636 0.364 0.000
D03 Melanoma in situ
0.636 0.364 0.000
J37 Chronic laryngitis and laryngotracheitis
0.636 0.364 0.000
Z99.2 Dependence on renal dialysis
0.636 0.364 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.635 0.365 0.000
I08.0 Disorders of both mitral and aortic valves
0.634 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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