TreeWAS – Variant ID: rs9262182

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	1.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000
E03 Other hypothyroidism	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001
E00-E07 Disorders of thyroid gland	0.999	0.001
C44.3 Skin of other and unspecified parts of face	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006
I25 Chronic ischaemic heart disease	0.992	0.008
C44.1 Skin of eyelid, including canthus	0.988	0.012
Chapter XIV Diseases of the genitourinary system	0.985	0.015
N17-N19 Renal failure	0.984	0.016
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.980	0.020
D37-D48 Neoplasms of uncertain or unknown behaviour	0.978	0.022
I21 Acute myocardial infarction	0.970	0.030
I24 Other acute ischaemic heart diseases	0.969	0.031
D10-D36 Benign neoplasms	0.969	0.031
N19 Unspecified renal failure	0.966	0.034
N18 Chronic renal failure	0.963	0.037
C43 Malignant melanoma of skin	0.958	0.042
I25.2 Old myocardial infarction	0.955	0.045
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.955	0.045
S40-S49 Injuries to the shoulder and upper arm	0.954	0.046
Chapter XX External causes of morbidity and mortality	0.947	0.053
I24.9 Acute ischaemic heart disease, unspecified	0.945	0.055
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.939	0.061
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.935	0.065
N18.9 Chronic renal failure, unspecified	0.931	0.069
I25.8 Other forms of chronic ischaemic heart disease	0.926	0.074
S42 Fracture of shoulder and upper arm	0.924	0.076
E20-E35 Disorders of other endocrine glands	0.923	0.077
I05-I09 Chronic rheumatic heart diseases	0.918	0.082
D22 Melanocytic naevi	0.916	0.084
I30-I52 Other forms of heart disease	0.916	0.084
D00-D09 In situ neoplasms	0.912	0.088
S60-S69 Injuries to the wrist and hand	0.903	0.097
C43.7 Malignant melanoma of lower limb, including hip	0.900	0.100
S50-S59 Injuries to the elbow and forearm	0.894	0.106
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.889	0.111
N10-N16 Renal tubulo-interstitial diseases	0.889	0.111
S20-S29 Injuries to the thorax	0.888	0.112
I45 Other conduction disorders	0.888	0.112
W00-W19 Falls	0.886	0.114
I21.9 Acute myocardial infarction, unspecified	0.884	0.116
E10-E14 Diabetes mellitus	0.878	0.122
I25.9 Chronic ischaemic heart disease, unspecified	0.878	0.122
D48.1 Connective and other soft tissue	0.875	0.125
D22.7 Melanocytic naevi of lower limb, including hip	0.868	0.132
N00-N08 Glomerular diseases	0.868	0.132
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.867	0.133
C44.4 Skin of scalp and neck	0.867	0.133
N99-N99 Other disorders of the genitourinary system	0.861	0.139
I21.4 Acute subendocardial myocardial infarction	0.860	0.140
D12.6 Colon, unspecified	0.857	0.143
S42.2 Fracture of upper end of humerus	0.856	0.144
D12.8 Rectum	0.852	0.148
D05 Carcinoma in situ of breast	0.852	0.148
C64-C68 Malignant neoplasms of urinary tract	0.848	0.152
S10-S19 Injuries to the neck	0.843	0.157
E10 Insulin-dependent diabetes mellitus	0.843	0.157
N18.2 Chronic kidney disease, stage 2	0.838	0.162
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.838	0.162
C85.1 B-cell lymphoma, unspecified	0.837	0.163
I21.1 Acute transmural myocardial infarction of inferior wall	0.832	0.168
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.831	0.169
S90-S99 Injuries to the ankle and foot	0.830	0.170
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.827	0.173
C43.4 Malignant melanoma of scalp and neck	0.824	0.176
W10 Fall on and from stairs and steps	0.823	0.177
D12.7 Rectosigmoid junction	0.812	0.188
S42.0 Fracture of clavicle	0.811	0.189
S61 Open wound of wrist and hand	0.811	0.189
D05.1 Intraductal carcinoma in situ	0.810	0.190
D22.5 Melanocytic naevi of trunk	0.809	0.191
C44.7 Skin of lower limb, including hip	0.809	0.191
W20-W49 Exposure to inanimate mechanical forces	0.808	0.192
S42.20 Fracture of upper end of humerus (closed)	0.808	0.192
I10-I15 Hypertensive diseases	0.802	0.198
I35 Nonrheumatic aortic valve disorders	0.802	0.198
C84 Peripheral and cutaneous T-cell lymphomas	0.796	0.204
D41.4 Bladder	0.796	0.204
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.792	0.208
S52 Fracture of forearm	0.792	0.208
D21 Other benign neoplasms of connective and other soft tissue	0.787	0.213
C85.7 Other specified types of non-Hodgkin's lymphoma	0.787	0.213
I07 Rheumatic tricuspid valve diseases	0.786	0.214
I24.8 Other forms of acute ischaemic heart disease	0.786	0.214
I45.3 Trifascicular block	0.786	0.214
X20-X29 Contact with venomous animals and plants	0.785	0.215
D12.4 Descending colon	0.783	0.217
S22 Fracture of rib(s), sternum and thoracic spine	0.781	0.219
I46 Cardiac arrest	0.778	0.222
N18.4 Chronic kidney disease, stage 4	0.778	0.222
D29 Benign neoplasm of male genital organs	0.778	0.222
D35 Benign neoplasm of other and unspecified endocrine glands	0.777	0.223
W10.8 Other specified place	0.777	0.223
N05 Unspecified nephritic syndrome	0.777	0.223
S64 Injury of nerves at wrist and hand level	0.777	0.223
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.776	0.224
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.772	0.228
D14 Benign neoplasm of middle ear and respiratory system	0.768	0.232
D12.5 Sigmoid colon	0.767	0.233
Chapter VIII Diseases of the ear and mastoid process	0.765	0.235
D22.3 Melanocytic naevi of other and unspecified parts of face	0.764	0.236
E05 Thyrotoxicosis [hyperthyroidism]	0.763	0.237
E27 Other disorders of adrenal gland	0.763	0.237
X60-X84 Intentional self-harm	0.762	0.238
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.760	0.240
S42.1 Fracture of scapula	0.759	0.241
D31 Benign neoplasm of eye and adnexa	0.758	0.241
D30 Benign neoplasm of urinary organs	0.758	0.242
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.758	0.242
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.758	0.242
I12 Hypertensive renal disease	0.755	0.245
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.755	0.245
I45.1 Other and unspecified right bundle-branch block	0.754	0.246
E10.3 With ophthalmic complications	0.754	0.246
N70-N77 Inflammatory diseases of female pelvic organs	0.753	0.247
C44.0 Skin of lip	0.749	0.251
C67 Malignant neoplasm of bladder	0.746	0.254
N10 Acute tubulo-interstitial nephritis	0.746	0.254
D48.6 Breast	0.746	0.254
I36 Nonrheumatic tricuspid valve disorders	0.745	0.255
C92 Myeloid leukaemia	0.744	0.256
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.744	0.256
I45.6 Preexcitation syndrome	0.743	0.257
I25.5 Ischaemic cardiomyopathy	0.742	0.258
E29 Testicular dysfunction	0.737	0.263
C83 Diffuse non-Hodgkin's lymphoma	0.737	0.263
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.735	0.264
E10.9 Without complications	0.735	0.265
E07 Other disorders of thyroid	0.735	0.265
N04 Nephrotic syndrome	0.735	0.265
I05 Rheumatic mitral valve diseases	0.734	0.266
I50 Heart failure	0.734	0.266
C43.3 Malignant melanoma of other and unspecified parts of face	0.733	0.267
N18.5 Chronic kidney disease, stage 5	0.733	0.267
D26 Other benign neoplasms of uterus	0.732	0.267
C44.9 Malignant neoplasm of skin, unspecified	0.731	0.269
D05.0 Lobular carcinoma in situ	0.731	0.269
S42.00 Fracture of clavicle (closed)	0.730	0.270
S70-S79 Injuries to the hip and thigh	0.730	0.270
C81 Hodgkin's disease	0.728	0.272
N17 Acute renal failure	0.728	0.272
D04 Carcinoma in situ of skin	0.727	0.273
E28 Ovarian dysfunction	0.726	0.274
D27 Benign neoplasm of ovary	0.726	0.274
E24 Cushing's syndrome	0.726	0.274
W50-W64 Exposure to animate mechanical forces	0.725	0.275
S61.0 Open wound of finger(s) without damage to nail	0.725	0.275
I09 Other rheumatic heart diseases	0.724	0.276
C88 Malignant immunoproliferative diseases	0.724	0.276
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.724	0.276
T36-T50 Poisoning by drugs, medicaments and biological substances	0.724	0.276
E06 Thyroiditis	0.724	0.276
V80-V89 Other land transport accidents	0.723	0.277
E10.4 With neurological complications	0.721	0.279
I35.9 Aortic valve disorder, unspecified	0.720	0.280
T15-T19 Effects of foreign body entering through natural orifice	0.718	0.281
I21.0 Acute transmural myocardial infarction of anterior wall	0.718	0.282
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C44.8 Overlapping lesion of skin	0.717	0.283
E03.8 Other specified hypothyroidism	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283
E00 Congenital iodine-deficiency syndrome	0.717	0.283
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283
W13 Fall from, out of or through building or structure	0.715	0.285
D10 Benign neoplasm of mouth and pharynx	0.714	0.286
N99.3 Prolapse of vaginal vault after hysterectomy	0.713	0.287
T66-T78 Other and unspecified effects of external causes	0.713	0.287
D45 Polycythaemia vera	0.712	0.287
T33-T35 Frostbite	0.712	0.288
T26-T28 Burns and corrosions confined to eye and internal organs	0.712	0.288
T20-T25 Burns and corrosions of external body surface, specified by site	0.712	0.288
T00-T07 Injuries involving multiple body regions	0.712	0.288
I70-I79 Diseases of arteries, arterioles and capillaries	0.712	0.288
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.712	0.288
I25.6 Silent myocardial ischaemia	0.711	0.288
I25.4 Coronary artery aneurysm	0.711	0.288
I25.0 Atherosclerotic cardiovascular disease, so described	0.711	0.288
D48.7 Other specified sites	0.710	0.290
D32 Benign neoplasm of meninges	0.710	0.290
D24 Benign neoplasm of breast	0.709	0.291
E13 Other specified diabetes mellitus	0.708	0.292
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.707	0.293
I45.4 Nonspecific intraventricular block	0.707	0.293
E26 Hyperaldosteronism	0.706	0.294
D22.2 Melanocytic naevi of ear and external auricular canal	0.705	0.295
N72 Inflammatory disease of cervix uteri	0.705	0.295
S52.6 Fracture of lower end of both ulna and radius	0.704	0.296
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.703	0.297
C95 Leukaemia of unspecified cell type	0.703	0.297
C94 Other leukaemias of specified cell type	0.703	0.297
C93 Monocytic leukaemia	0.703	0.297
C86 Other specified types of T/NK-cell lymphoma	0.703	0.297
D09 Carcinoma in situ of other and unspecified sites	0.702	0.298
V20-V29 Motorcycle rider injured in transport accident	0.702	0.298
C44.2 Skin of ear and external auricular canal	0.702	0.298
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.701	0.299
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.701	0.299
S10 Superficial injury of neck	0.701	0.299
I08 Multiple valve diseases	0.701	0.299
N11 Chronic tubulo-interstitial nephritis	0.700	0.300
D48.5 Skin	0.698	0.302
D03 Melanoma in situ	0.698	0.302
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.697	0.303
S40 Superficial injury of shoulder and upper arm	0.697	0.303
S46 Injury of muscle and tendon at shoulder and upper arm level	0.696	0.303
E50-E64 Other nutritional deficiencies	0.696	0.303
I21.X Presumed acute myicardial infaction (unconfirmed)	0.695	0.304
I21.3 Acute transmural myocardial infarction of unspecified site	0.695	0.304
I24.1 Dressler's syndrome	0.695	0.305
D28 Benign neoplasm of other and unspecified female genital organs	0.694	0.305
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.694	0.305
D19 Benign neoplasm of mesothelial tissue	0.694	0.305
D16 Benign neoplasm of bone and articular cartilage	0.694	0.305
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.694	0.305
S20 Superficial injury of thorax	0.694	0.306
S49 Other and unspecified injuries of shoulder and upper arm	0.692	0.308
S22.3 Fracture of rib	0.692	0.308
I07.1 Tricuspid insufficiency	0.692	0.308
D36 Benign neoplasm of other and unspecified sites	0.692	0.308
S50 Superficial injury of forearm	0.691	0.308
Chapter XXII Codes for special purposes	0.691	0.309
I12.0 Hypertensive renal disease with renal failure	0.691	0.309
D12.9 Anus and anal canal	0.691	0.309
N18.8 Other chronic renal failure	0.690	0.310
N18.1 Chronic kidney disease, stage 1	0.690	0.310
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.690	0.310
H65-H75 Diseases of middle ear and mastoid	0.689	0.311
V40-V49 Car occupant injured in transport accident	0.689	0.311
D48.0 Bone and articular cartilage	0.689	0.311
Chapter VII Diseases of the eye and adnexa	0.687	0.313
S56 Injury of muscle and tendon at forearm level	0.687	0.313
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.687	0.313
C43.8 Overlapping malignant melanoma of skin	0.686	0.313
C43.2 Malignant melanoma of ear and external auricular canal	0.686	0.313
C43.1 Malignant melanoma of eyelid, including canthus	0.686	0.313
C43.0 Malignant melanoma of lip	0.686	0.313
W17 Other fall from one level to another	0.685	0.315
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.685	0.315
C85.0 Lymphosarcoma	0.685	0.315
E40-E46 Malnutrition	0.685	0.315
S48 Traumatic amputation of shoulder and upper arm	0.684	0.316
S45 Injury of blood vessels at shoulder and upper arm level	0.684	0.316
S44 Injury of nerves at shoulder and upper arm level	0.684	0.316
S41 Open wound of shoulder and upper arm	0.684	0.316
S47 Crushing injury of shoulder and upper arm	0.684	0.316
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.684	0.316
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.683	0.317
C43.9 Malignant melanoma of skin, unspecified	0.682	0.317
E34 Other endocrine disorders	0.682	0.318
T79-T79 Certain early complications of trauma	0.681	0.318
N25-N29 Other disorders of kidney and ureter	0.680	0.320
Y35-Y36 Legal intervention and operations of war	0.679	0.321
Y10-Y34 Event of undetermined intent	0.679	0.321
Y00-Y09 Assault	0.679	0.321
X85-X99 Assault	0.679	0.321
X58-X59 Accidental exposure to other and unspecified factors	0.679	0.321
X50-X57 Overexertion, travel and privation	0.679	0.321
X40-X49 Accidental poisoning by and exposure to noxious substances	0.679	0.321
X30-X39 Exposure to forces of nature	0.679	0.321
X10-X19 Contact with heat and hot substances	0.679	0.321
X00-X09 Exposure to smoke, fire and flames	0.679	0.321
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.679	0.321
W75-W84 Other accidental threats to breathing	0.679	0.321
W65-W74 Accidental drowning and submersion	0.679	0.321
V98-V99 Other and unspecified transport accidents	0.679	0.321
V95-V97 Air and space transport accidents	0.679	0.321
V90-V94 Water transport accidents	0.679	0.321
V70-V79 Bus occupant injured in transport accident	0.679	0.321
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.679	0.321
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.679	0.321
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.679	0.321
V01-V09 Pedestrian injured in transport accident	0.679	0.321
C44.6 Skin of upper limb, including shoulder	0.679	0.321
S64.4 Injury of digital nerve of other finger	0.678	0.322
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.677	0.323
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.676	0.324
C66 Malignant neoplasm of ureter	0.676	0.324
S67 Crushing injury of wrist and hand	0.675	0.325
C44.5 Skin of trunk	0.675	0.325
C67.9 Bladder, unspecified	0.674	0.326
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.674	0.326
D12.1 Appendix	0.673	0.327
I45.9 Conduction disorder, unspecified	0.673	0.327
W18 Other fall on same level	0.672	0.327
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.671	0.329
D48.4 Peritoneum	0.671	0.329
D48.3 Retroperitoneum	0.671	0.329
D48.2 Peripheral nerves and autonomic nervous system	0.671	0.329
N05.9 Unspecified	0.671	0.329
I35.2 Aortic (valve) stenosis with insufficiency	0.671	0.329
Chapter V Mental and behavioural disorders	0.670	0.330
X23 Contact with hornets, wasps and bees	0.668	0.332
I31 Other diseases of pericardium	0.668	0.332
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.667	0.333
S29 Other and unspecified injuries of thorax	0.667	0.333
V10-V19 Pedal cyclist injured in transport accident	0.666	0.334
I22 Subsequent myocardial infarction	0.665	0.335
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.663	0.336
S42.9 Fracture of shoulder girdle, part unspecified	0.662	0.338
S42.8 Fracture of other parts of shoulder and upper arm	0.662	0.338
S42.7 Multiple fractures of clavicle, scapula and humerus	0.662	0.338
E35 Disorders of endocrine glands in diseases classified elsewhere	0.662	0.338
E32 Diseases of thymus	0.662	0.338
E31 Polyglandular dysfunction	0.662	0.338
E30 Disorders of puberty, not elsewhere classified	0.662	0.338
E25 Adrenogenital disorders	0.662	0.338
E20 Hypoparathyroidism	0.662	0.338
S12 Fracture of neck	0.662	0.338
D17 Benign lipomatous neoplasm	0.662	0.338
W07 Fall involving chair	0.661	0.339
I30 Acute pericarditis	0.660	0.340
I06 Rheumatic aortic valve diseases	0.658	0.342
D44.1 Adrenal gland	0.658	0.342
S42.3 Fracture of shaft of humerus	0.658	0.342
I46.0 Cardiac arrest with successful resuscitation	0.657	0.343
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.657	0.343
D22.9 Melanocytic naevi, unspecified	0.657	0.343
I52 Other heart disorders in diseases classified elsewhere	0.657	0.343
I48 Atrial fibrillation and flutter	0.657	0.343
I43 Cardiomyopathy in diseases classified elsewhere	0.657	0.343
I41 Myocarditis in diseases classified elsewhere	0.657	0.343
I40 Acute myocarditis	0.657	0.343
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.657	0.343
I37 Pulmonary valve disorders	0.657	0.343
I32 Pericarditis in diseases classified elsewhere	0.657	0.343
S66 Injury of muscle and tendon at wrist and hand level	0.656	0.344
E23 Hypofunction and other disorders of pituitary gland	0.655	0.345
S90 Superficial injury of ankle and foot	0.655	0.345
D02 Carcinoma in situ of middle ear and respiratory system	0.654	0.346
D01 Carcinoma in situ of other and unspecified digestive organs	0.654	0.346
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.654	0.346
C43.6 Malignant melanoma of upper limb, including shoulder	0.654	0.346
W25 Contact with sharp glass	0.651	0.349
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.648	0.351
W06 Fall involving bed	0.648	0.352
S65 Injury of blood vessels at wrist and hand level	0.648	0.352
C43.5 Malignant melanoma of trunk	0.647	0.353
Q80-Q89 Other congenital malformations	0.644	0.356
C92.1 Chronic myeloid leukaemia	0.644	0.356
I12.9 Hypertensive renal disease without renal failure	0.644	0.356
I25.1 Atherosclerotic heart disease	0.643	0.357
S52.60 Fracture of lower end of both ulna and radius (closed)	0.642	0.358
S61.8 Open wound of other parts of wrist and hand	0.642	0.358
N05.1 Focal and segmental glomerular lesions	0.642	0.358
S59 Other and unspecified injuries of forearm	0.641	0.359
S58 Traumatic amputation of forearm	0.641	0.359
S57 Crushing injury of forearm	0.641	0.359
S55 Injury of blood vessels at forearm level	0.641	0.359
S54 Injury of nerves at forearm level	0.641	0.359
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.641	0.359
S91 Open wound of ankle and foot	0.641	0.359
D29.1 Prostate	0.641	0.359
S42.10 Fracture of scapula (closed)	0.641	0.359
N04.9 Unspecified	0.639	0.361
I50.1 Left ventricular failure	0.639	0.361
Q20-Q28 Congenital malformations of the circulatory system	0.639	0.361
D35.0 Adrenal gland	0.638	0.362
N03 Chronic nephritic syndrome	0.638	0.362
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.637	0.362
N15 Other renal tubulo-interstitial diseases	0.637	0.362
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.637	0.362
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.637	0.363
S26 Injury of heart	0.637	0.363
S25 Injury of blood vessels of thorax	0.637	0.363
S24 Injury of nerves and spinal cord at thorax level	0.637	0.363
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.637	0.363
S21 Open wound of thorax	0.637	0.363
Y60-Y69 Misadventures to patients during surgical and medical care	0.637	0.363
I45.8 Other specified conduction disorders	0.637	0.363
I45.2 Bifascicular block	0.637	0.363
I45.0 Right fascicular block	0.637	0.363
H25-H28 Disorders of lens	0.636	0.364
W16 Diving or jumping into water causing injury other than drowning or submersion	0.635	0.364
W15 Fall from cliff	0.635	0.364
W14 Fall from tree	0.635	0.364
W12 Fall on and from scaffolding	0.635	0.364
W11 Fall on and from ladder	0.635	0.364
W09 Fall involving playground equipment	0.635	0.364
W08 Fall involving other furniture	0.635	0.364
W05 Fall involving wheelchair	0.635	0.364
W04 Fall while being carried or supported by other persons	0.635	0.364
W03 Other fall on same level due to collision with, or pushing by, another person	0.635	0.364
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.635	0.364
W01 Fall on same level from slipping, tripping and stumbling	0.635	0.364
W00 Fall on same level involving ice and snow	0.635	0.364
I25.3 Aneurysm of heart	0.635	0.365
E27.9 Disorder of adrenal gland, unspecified	0.633	0.367
Chapter XV Pregnancy, childbirth and the puerperium	0.632	0.368
S27 Injury of other and unspecified intrathoracic organs	0.631	0.369
W44 Foreign body entering into or through eye or natural orifice	0.631	0.369
D39.1 Ovary	0.631	0.369
N18.0 End-stage renal disease	0.631	0.369
C91 Lymphoid leukaemia	0.631	0.369
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.630	0.370
E12 Malnutrition-related diabetes mellitus	0.630	0.370
C84.4 Peripheral T-cell lymphoma	0.629	0.371
E05.9 Thyrotoxicosis, unspecified	0.629	0.371
S22.30 Fracture of rib (closed)	0.629	0.371
S51 Open wound of forearm	0.628	0.372
H71 Cholesteatoma of middle ear	0.627	0.373
I45.5 Other specified heart block	0.627	0.373
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.627	0.373
S99 Other and unspecified injuries of ankle and foot	0.626	0.374
Y79 Orthopaedic devices associated with adverse incidents	0.626	0.374
S68 Traumatic amputation of wrist and hand	0.626	0.374
H26 Other cataract	0.625	0.375
I33 Acute and subacute endocarditis	0.624	0.376
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.623	0.377
N07 Hereditary nephropathy, not elsewhere classified	0.622	0.378
N06 Isolated proteinuria with specified morphological lesion	0.622	0.378
N01 Rapidly progressive nephritic syndrome	0.622	0.378
N00 Acute nephritic syndrome	0.622	0.378
Q38-Q45 Other congenital malformations of the digestive system	0.622	0.378
D41.9 Urinary organ, unspecified	0.622	0.378
D41.7 Other urinary organs	0.622	0.378
D41.3 Urethra	0.622	0.378
D41.2 Ureter	0.622	0.378
D41.1 Renal pelvis	0.622	0.378
D12.3 Transverse colon	0.621	0.379
S42.4 Fracture of lower end of humerus	0.621	0.379
S60 Superficial injury of wrist and hand	0.621	0.379
C15-C26 Malignant neoplasms of digestive organs	0.621	0.379
S61.9 Open wound of wrist and hand, part unspecified	0.621	0.379
I71 Aortic aneurysm and dissection	0.621	0.379
I35.1 Aortic (valve) insufficiency	0.620	0.380
S70 Superficial injury of hip and thigh	0.620	0.380
E10.2 With renal complications	0.619	0.381
C84.5 Other and unspecified T-cell lymphomas	0.619	0.381
S22.1 Multiple fractures of thoracic spine	0.617	0.383
D33 Benign neoplasm of brain and other parts of central nervous system	0.614	0.386
S42.21 Fracture of upper end of humerus (open)	0.614	0.386
D22.1 Melanocytic naevi of eyelid, including canthus	0.612	0.388
I20 Angina pectoris	0.612	0.388
S69 Other and unspecified injuries of wrist and hand	0.611	0.389
D05.7 Other carcinoma in situ of breast	0.611	0.389
N08 Glomerular disorders in diseases classified elsewhere	0.610	0.389
I21.2 Acute transmural myocardial infarction of other sites	0.608	0.392
C68 Malignant neoplasm of other and unspecified urinary organs	0.608	0.392
C65 Malignant neoplasm of renal pelvis	0.608	0.392
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.608	0.392
D31.0 Conjunctiva	0.608	0.392
D30.3 Bladder	0.608	0.392
D46 Myelodysplastic syndromes	0.607	0.393
S92 Fracture of foot, except ankle	0.607	0.393
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.605	0.395
S19 Other and unspecified injuries of neck	0.605	0.395
S17 Crushing injury of neck	0.605	0.395
S15 Injury of blood vessels at neck level	0.605	0.395
S14 Injury of nerves and spinal cord at neck level	0.605	0.395
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.605	0.395
S11 Open wound of neck	0.605	0.395
S18 Traumatic amputation at neck level	0.605	0.395
S16 Injury of muscle and tendon at neck level	0.605	0.395
E10.8 With unspecified complications	0.605	0.395
E10.7 With multiple complications	0.605	0.395
E10.6 With other specified complications	0.605	0.395
E10.0 With coma	0.605	0.395
I42 Cardiomyopathy	0.604	0.396
E29.1 Testicular hypofunction	0.604	0.396
S52.2 Fracture of shaft of ulna	0.603	0.397
W29 Contact with other powered hand tools and household machinery	0.602	0.398
S52.5 Fracture of lower end of radius	0.602	0.398
E10.5 With peripheral circulatory complications	0.602	0.398
D14.0 Middle ear, nasal cavity and accessory sinuses	0.602	0.398
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.602	0.398
H74 Other disorders of middle ear and mastoid	0.602	0.398
Q00-Q07 Congenital malformations of the nervous system	0.601	0.398
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.601	0.399
Q35-Q37 Cleft lip and cleft palate	0.601	0.399
Q30-Q34 Congenital malformations of the respiratory system	0.601	0.399
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.601	0.399
D38.1 Trachea, bronchus and lung	0.600	0.399
D04.3 Skin of other and unspecified parts of face	0.600	0.400
C90 Multiple myeloma and malignant plasma cell neoplasms	0.600	0.400
H26.9 Cataract, unspecified	0.600	0.400
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.600	0.400
S10.9 Superficial injury of neck, part unspecified	0.600	0.400
E27.8 Other specified disorders of adrenal gland	0.599	0.401
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.599	0.401
W22 Striking against or struck by other objects	0.599	0.401
N99.4 Postprocedural pelvic peritoneal adhesions	0.598	0.402
I46.9 Cardiac arrest, unspecified	0.597	0.403
S22.4 Multiple fractures of ribs	0.597	0.403
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.596	0.404

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations