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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114418084
log Bayes Factor = 12.5108
Chromosome 4   position 106,374,291  (GRCh37) Explore rs114418084 on Ensembl!
Variant rs114418084 is part of Cluster X0123

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
I30-I52 Other forms of heart disease
0.988 0.012 0.000
Chapter VIII Diseases of the ear and mastoid process
0.986 0.014 0.000
E70-E90 Metabolic disorders
0.985 0.015 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.968 0.032 0.000
Chapter V Mental and behavioural disorders
0.965 0.035 0.000
J20-J22 Other acute lower respiratory infections
0.965 0.035 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
Chapter VII Diseases of the eye and adnexa
0.956 0.044 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.953 0.047 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.953 0.047 0.000
J22 Unspecified acute lower respiratory infection
0.948 0.052 0.000
E00-E07 Disorders of thyroid gland
0.948 0.052 0.000
H90-H95 Other disorders of ear
0.946 0.054 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.946 0.054 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.944 0.056 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.940 0.060 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.939 0.061 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.937 0.063 0.000
S20-S29 Injuries to the thorax
0.936 0.064 0.000
S00-S09 Injuries to the head
0.932 0.068 0.000
I45 Other conduction disorders
0.930 0.070 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.924 0.076 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.922 0.078 0.000
I60-I69 Cerebrovascular diseases
0.921 0.079 0.000
H30-H36 Disorders of choroid and retina
0.914 0.086 0.000
J00-J06 Acute upper respiratory infections
0.914 0.086 0.000
Chapter I Certain infectious and parasitic diseases
0.911 0.089 0.000
I35 Nonrheumatic aortic valve disorders
0.910 0.090 0.000
E83 Disorders of mineral metabolism
0.907 0.093 0.000
I05-I09 Chronic rheumatic heart diseases
0.900 0.100 0.000
E05.9 Thyrotoxicosis, unspecified
0.898 0.102 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.897 0.103 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.897 0.103 0.000
E87.5 Hyperkalaemia
0.895 0.105 0.000
H60-H62 Diseases of external ear
0.891 0.109 0.000
I34 Nonrheumatic mitral valve disorders
0.891 0.109 0.000
I45.1 Other and unspecified right bundle-branch block
0.886 0.114 0.000
L20-L30 Dermatitis and eczema
0.881 0.119 0.000
H35 Other retinal disorders
0.879 0.121 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.874 0.126 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.873 0.127 0.000
I47 Paroxysmal tachycardia
0.871 0.129 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.871 0.129 0.000
V40-V49 Car occupant injured in transport accident
0.866 0.134 0.000
H91 Other hearing loss
0.862 0.138 0.000
S90-S99 Injuries to the ankle and foot
0.861 0.139 0.000
H90 Conductive and sensorineural hearing loss
0.860 0.140 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.859 0.141 0.000
I73 Other peripheral vascular diseases
0.857 0.143 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.857 0.143 0.000
F17.1 Harmful use
0.857 0.143 0.000
H10-H13 Disorders of conjunctiva
0.856 0.144 0.000
H35.3 Degeneration of macula and posterior pole
0.852 0.148 0.000
T93 Sequelae of injuries of lower limb
0.850 0.150 0.000
S80-S89 Injuries to the knee and lower leg
0.848 0.152 0.000
I34.0 Mitral (valve) insufficiency
0.847 0.153 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.847 0.153 0.000
E10-E14 Diabetes mellitus
0.846 0.154 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.844 0.156 0.000
Chapter II Neoplasms
0.842 0.158 0.000
I77 Other disorders of arteries and arterioles
0.842 0.158 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.841 0.159 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.840 0.160 0.000
S09 Other and unspecified injuries of head
0.838 0.162 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.837 0.163 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.836 0.164 0.000
S50-S59 Injuries to the elbow and forearm
0.833 0.167 0.000
B95-B98 Bacterial, viral and other infectious agents
0.833 0.167 0.000
E83.1 Disorders of iron metabolism
0.833 0.167 0.000
S20 Superficial injury of thorax
0.829 0.170 0.000
W00-W19 Falls
0.824 0.176 0.000
I60 Subarachnoid haemorrhage
0.822 0.178 0.000
I72 Other aneurysm
0.820 0.180 0.000
B25-B34 Other viral diseases
0.820 0.180 0.000
H61 Other disorders of external ear
0.820 0.180 0.000
J81 Pulmonary oedema
0.817 0.183 0.000
I30 Acute pericarditis
0.814 0.186 0.000
I73.0 Raynaud's syndrome
0.811 0.189 0.000
Chapter XIV Diseases of the genitourinary system
0.810 0.190 0.000
E88 Other metabolic disorders
0.808 0.192 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.808 0.192 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.805 0.195 0.000
E73 Lactose intolerance
0.803 0.197 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.802 0.198 0.000
Y42.7 Androgens and anabolic congeners
0.802 0.198 0.000
H91.9 Hearing loss, unspecified
0.801 0.199 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.800 0.200 0.000
I35.0 Aortic (valve) stenosis
0.800 0.200 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.798 0.202 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.798 0.202 0.000
N60-N64 Disorders of breast
0.797 0.203 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.795 0.205 0.000
Q80-Q89 Other congenital malformations
0.794 0.206 0.000
T42.4 Benzodiazepines
0.793 0.207 0.000
S05 Injury of eye and orbit
0.793 0.207 0.000
L90 Atrophic disorders of skin
0.792 0.208 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.792 0.208 0.000
H65-H75 Diseases of middle ear and mastoid
0.792 0.208 0.000
V80-V89 Other land transport accidents
0.789 0.211 0.000
L30 Other dermatitis
0.785 0.215 0.000
H11 Other disorders of conjunctiva
0.784 0.216 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.781 0.219 0.000
I08 Multiple valve diseases
0.779 0.221 0.000
I69 Sequelae of cerebrovascular disease
0.777 0.223 0.000
Y42.5 Other oestrogens and progestogens
0.776 0.224 0.000
I77.1 Stricture of artery
0.774 0.226 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.773 0.227 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.772 0.228 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.772 0.228 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.772 0.228 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.771 0.229 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.771 0.229 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.770 0.230 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.770 0.230 0.000
E40-E46 Malnutrition
0.769 0.231 0.000
C34 Malignant neoplasm of bronchus and lung
0.766 0.234 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.765 0.235 0.000
W20-W49 Exposure to inanimate mechanical forces
0.764 0.236 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.764 0.236 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.763 0.237 0.000
I70 Atherosclerosis
0.761 0.239 0.000
F10.3 Withdrawal state
0.760 0.240 0.000
E65-E68 Obesity and other hyperalimentation
0.760 0.240 0.000
E04 Other non-toxic goitre
0.760 0.240 0.000
H35.0 Background retinopathy and retinal vascular changes
0.760 0.240 0.000
Q60-Q64 Congenital malformations of the urinary system
0.758 0.242 0.000
H93 Other disorders of ear, not elsewhere classified
0.758 0.242 0.000
T79-T79 Certain early complications of trauma
0.755 0.244 0.000
H90.2 Conductive hearing loss, unspecified
0.755 0.245 0.000
L57.0 Actinic keratosis
0.754 0.246 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.753 0.246 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.753 0.247 0.000
H25-H28 Disorders of lens
0.753 0.247 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.753 0.247 0.000
I27 Other pulmonary heart diseases
0.752 0.248 0.000
L28 Lichen simplex chronicus and prurigo
0.751 0.249 0.000
B34 Viral infection of unspecified site
0.751 0.249 0.000
E10 Insulin-dependent diabetes mellitus
0.751 0.249 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.750 0.250 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.748 0.252 0.000
J95-J99 Other diseases of the respiratory system
0.748 0.252 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.748 0.252 0.000
T86 Failure and rejection of transplanted organs and tissues
0.747 0.252 0.000
W50-W64 Exposure to animate mechanical forces
0.746 0.254 0.000
J60-J70 Lung diseases due to external agents
0.745 0.255 0.000
Q50-Q56 Congenital malformations of genital organs
0.745 0.255 0.000
S22.0 Fracture of thoracic vertebra
0.745 0.255 0.000
S70-S79 Injuries to the hip and thigh
0.745 0.255 0.000
B99-B99 Other infectious diseases
0.744 0.255 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.743 0.257 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.743 0.257 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.742 0.258 0.000
L50-L54 Urticaria and erythema
0.742 0.258 0.000
T87 Complications peculiar to reattachment and amputation
0.742 0.258 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.740 0.260 0.000
T90 Sequelae of injuries of head
0.740 0.260 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.739 0.261 0.000
C92 Myeloid leukaemia
0.738 0.262 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.738 0.262 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.737 0.263 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.737 0.263 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.736 0.264 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.736 0.264 0.000
E83.5 Disorders of calcium metabolism
0.736 0.264 0.000
C15-C26 Malignant neoplasms of digestive organs
0.734 0.266 0.000
S01 Open wound of head
0.734 0.266 0.000
J03 Acute tonsillitis
0.733 0.267 0.000
F60-F69 Disorders of adult personality and behaviour
0.732 0.268 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.732 0.268 0.000
T92 Sequelae of injuries of upper limb
0.731 0.268 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.731 0.269 0.000
I51 Complications and ill-defined descriptions of heart disease
0.731 0.269 0.000
T93.2 Sequelae of other fractures of lower limb
0.728 0.271 0.000
H36 Retinal disorders in diseases classified elsewhere
0.727 0.273 0.000
I67 Other cerebrovascular diseases
0.727 0.273 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.726 0.274 0.000
T91 Sequelae of injuries of neck and trunk
0.725 0.275 0.000
I47.0 Reentry ventricular arrhythmia
0.725 0.275 0.000
S60-S69 Injuries to the wrist and hand
0.724 0.276 0.000
N62 Hypertrophy of breast
0.724 0.276 0.000
I09 Other rheumatic heart diseases
0.724 0.276 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.723 0.277 0.000
F10.0 Acute intoxication
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.721 0.279 0.000
S09.9 Unspecified injury of head
0.721 0.279 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.720 0.280 0.000
J90-J94 Other diseases of pleura
0.719 0.281 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.718 0.282 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
L30.9 Dermatitis, unspecified
0.716 0.284 0.000
J01 Acute sinusitis
0.715 0.285 0.000
J06.9 Acute upper respiratory infection, unspecified
0.715 0.285 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.287 0.000
Y10-Y34 Event of undetermined intent
0.712 0.287 0.000
Y00-Y09 Assault
0.712 0.287 0.000
X85-X99 Assault
0.712 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.287 0.000
X50-X57 Overexertion, travel and privation
0.712 0.287 0.000
X30-X39 Exposure to forces of nature
0.712 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.287 0.000
X10-X19 Contact with heat and hot substances
0.712 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.287 0.000
W75-W84 Other accidental threats to breathing
0.712 0.287 0.000
W65-W74 Accidental drowning and submersion
0.712 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.287 0.000
V95-V97 Air and space transport accidents
0.712 0.287 0.000
V90-V94 Water transport accidents
0.712 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.287 0.000
H61.3 Acquired stenosis of external ear canal
0.712 0.288 0.000
S02 Fracture of skull and facial bones
0.711 0.289 0.000
I47.1 Supraventricular tachycardia
0.710 0.290 0.000
S40-S49 Injuries to the shoulder and upper arm
0.709 0.290 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.709 0.291 0.000
M05-M14 Inflammatory polyarthropathies
0.709 0.291 0.000
L85 Other epidermal thickening
0.708 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I37 Pulmonary valve disorders
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
X60-X84 Intentional self-harm
0.708 0.292 0.000
Y40 Systemic antibiotics
0.707 0.292 0.000
E85 Amyloidosis
0.706 0.294 0.000
E84 Cystic fibrosis
0.706 0.294 0.000
E79 Disorders of purine and pyrimidine metabolism
0.706 0.294 0.000
E77 Disorders of glycoprotein metabolism
0.706 0.294 0.000
E76 Disorders of glycosaminoglycan metabolism
0.706 0.294 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.706 0.294 0.000
E74 Other disorders of carbohydrate metabolism
0.706 0.294 0.000
E72 Other disorders of amino-acid metabolism
0.706 0.294 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.706 0.294 0.000
E70 Disorders of aromatic amino-acid metabolism
0.706 0.294 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.706 0.294 0.000
L60-L75 Disorders of skin appendages
0.706 0.294 0.000
S20.2 Contusion of thorax
0.706 0.294 0.000
S90 Superficial injury of ankle and foot
0.705 0.295 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.704 0.296 0.000
S09.8 Other specified injuries of head
0.703 0.297 0.000
D50-D53 Nutritional anaemias
0.703 0.297 0.000
I38 Endocarditis, valve unspecified
0.703 0.297 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.703 0.297 0.000
B34.9 Viral infection, unspecified
0.701 0.299 0.000
I45.5 Other specified heart block
0.701 0.299 0.000
H80-H83 Diseases of inner ear
0.700 0.300 0.000
L90.5 Scar conditions and fibrosis of skin
0.700 0.300 0.000
Y44 Agents primarily affecting blood constituents
0.698 0.302 0.000
I44 Atrioventricular and left bundle-branch block
0.698 0.302 0.000
L40-L45 Papulosquamous disorders
0.698 0.302 0.000
H25 Senile cataract
0.698 0.302 0.000
S52 Fracture of forearm
0.697 0.303 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.696 0.304 0.000
T51 Toxic effect of alcohol
0.695 0.305 0.000
L10-L14 Bullous disorders
0.694 0.306 0.000
H33 Retinal detachments and breaks
0.694 0.306 0.000
T82.1 Mechanical complication of cardiac electronic device
0.692 0.308 0.000
E06 Thyroiditis
0.692 0.308 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.692 0.308 0.000
F70-F79 Mental retardation
0.692 0.308 0.000
J21 Acute bronchiolitis
0.692 0.308 0.000
J20 Acute bronchitis
0.692 0.308 0.000
T66-T78 Other and unspecified effects of external causes
0.692 0.308 0.000
N60 Benign mammary dysplasia
0.692 0.308 0.000
F10.2 Dependence syndrome
0.691 0.309 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.691 0.309 0.000
I30.9 Acute pericarditis, unspecified
0.690 0.310 0.000
T82.3 Mechanical complication of other vascular grafts
0.690 0.310 0.000
J04 Acute laryngitis and tracheitis
0.689 0.311 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.689 0.311 0.000
Y57 Other and unspecified drugs and medicaments
0.688 0.312 0.000
V48 Car occupant injured in noncollision transport accident
0.688 0.312 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.686 0.314 0.000
I74 Arterial embolism and thrombosis
0.686 0.314 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.685 0.315 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.684 0.316 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.684 0.316 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.684 0.316 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.684 0.316 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.684 0.316 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.684 0.316 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.684 0.316 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.684 0.316 0.000
T36 Poisoning by systemic antibiotics
0.684 0.316 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.683 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.684 0.316 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.683 0.317 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.682 0.318 0.000
Y84.8 Other medical procedures
0.682 0.318 0.000
E87.2 Acidosis
0.680 0.320 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.680 0.320 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.680 0.320 0.000
E00 Congenital iodine-deficiency syndrome
0.680 0.320 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.680 0.320 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.679 0.321 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.679 0.321 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.679 0.321 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.678 0.322 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.678 0.322 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.678 0.322 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.678 0.322 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.678 0.322 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.678 0.322 0.000
F11 Mental and behavioural disorders due to use of opioids
0.678 0.322 0.000
F17.2 Dependence syndrome
0.677 0.323 0.000
N64 Other disorders of breast
0.677 0.323 0.000
Y59 Other and unspecified vaccines and biological substances
0.677 0.323 0.000
Y58 Bacterial vaccines
0.677 0.323 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.323 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.323 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.677 0.323 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.677 0.323 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
Y48 Anaesthetics and therapeutic gases
0.677 0.323 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.677 0.323 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.677 0.323 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.677 0.323 0.000
E11 Non-insulin-dependent diabetes mellitus
0.677 0.323 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.323 0.000
C92.1 Chronic myeloid leukaemia
0.676 0.324 0.000
Y43 Primarily systemic agents
0.676 0.324 0.000
E87.6 Hypokalaemia
0.676 0.324 0.000
T93.1 Sequelae of fracture of femur
0.675 0.325 0.000
I33 Acute and subacute endocarditis
0.675 0.325 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.675 0.325 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.674 0.326 0.000
T98 Sequelae of other and unspecified effects of external causes
0.674 0.326 0.000
T95 Sequelae of burns, corrosions and frostbite
0.674 0.326 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.674 0.326 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.674 0.326 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.674 0.326 0.000
F30-F39 Mood [affective] disorders
0.674 0.326 0.000
F99-F99 Unspecified mental disorder
0.674 0.326 0.000
E87.4 Mixed disorder of acid-base balance
0.673 0.327 0.000
E87.3 Alkalosis
0.673 0.327 0.000
N25-N29 Other disorders of kidney and ureter
0.673 0.327 0.000
H35.4 Peripheral retinal degeneration
0.673 0.327 0.000
A80-A89 Viral infections of the central nervous system
0.673 0.327 0.000
I72.3 Aneurysm of iliac artery
0.672 0.327 0.000
E73.9 Lactose intolerance, unspecified
0.672 0.328 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.672 0.328 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.672 0.328 0.000
Q35-Q37 Cleft lip and cleft palate
0.672 0.328 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.672 0.328 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.672 0.328 0.000
Q00-Q07 Congenital malformations of the nervous system
0.672 0.328 0.000
L81 Other disorders of pigmentation
0.672 0.328 0.000
S29 Other and unspecified injuries of thorax
0.671 0.329 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.671 0.329 0.000
S26 Injury of heart
0.671 0.329 0.000
S25 Injury of blood vessels of thorax
0.671 0.329 0.000
S24 Injury of nerves and spinal cord at thorax level
0.671 0.329 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.671 0.329 0.000
S21 Open wound of thorax
0.671 0.329 0.000
S89 Other and unspecified injuries of lower leg
0.670 0.329 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.670 0.330 0.000
Q65 Congenital deformities of hip
0.670 0.330 0.000
H90.5 Sensorineural hearing loss, unspecified
0.669 0.331 0.000
H61.8 Other specified disorders of external ear
0.669 0.331 0.000
V20-V29 Motorcycle rider injured in transport accident
0.669 0.331 0.000
I05 Rheumatic mitral valve diseases
0.668 0.332 0.000
S22.3 Fracture of rib
0.668 0.332 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.668 0.332 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.668 0.332 0.000
S08 Traumatic amputation of part of head
0.668 0.332 0.000
S07 Crushing injury of head
0.668 0.332 0.000
S04 Injury of cranial nerves
0.668 0.332 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.668 0.332 0.000
S82 Fracture of lower leg, including ankle
0.668 0.332 0.000
H61.2 Impacted cerumen
0.667 0.333 0.000
J40-J47 Chronic lower respiratory diseases
0.667 0.333 0.000
I45.8 Other specified conduction disorders
0.667 0.333 0.000
I45.4 Nonspecific intraventricular block
0.667 0.333 0.000
I45.3 Trifascicular block
0.667 0.333 0.000
I45.2 Bifascicular block
0.667 0.333 0.000
I45.0 Right fascicular block
0.667 0.333 0.000
H11.1 Conjunctival degenerations and deposits
0.666 0.334 0.000
C20 Malignant neoplasm of rectum
0.666 0.334 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.665 0.334 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.665 0.335 0.000
D50 Iron deficiency anaemia
0.665 0.335 0.000
C34.1 Upper lobe, bronchus or lung
0.665 0.335 0.000
I08.0 Disorders of both mitral and aortic valves
0.665 0.335 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.664 0.336 0.000
F80-F89 Disorders of psychological development
0.664 0.336 0.000
S92 Fracture of foot, except ankle
0.662 0.337 0.000
E05.8 Other thyrotoxicosis
0.662 0.337 0.000
E05.5 Thyroid crisis or storm
0.662 0.337 0.000
E05.4 Thyrotoxicosis factitia
0.662 0.337 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.662 0.337 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.662 0.337 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.662 0.337 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.661 0.339 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.661 0.339 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.661 0.339 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.661 0.339 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.661 0.339 0.000
I45.9 Conduction disorder, unspecified
0.661 0.339 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.661 0.339 0.000
I72.8 Aneurysm of other specified arteries
0.661 0.339 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.660 0.339 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.660 0.339 0.000
J02 Acute pharyngitis
0.660 0.340 0.000
I07 Rheumatic tricuspid valve diseases
0.660 0.340 0.000
C34.9 Bronchus or lung, unspecified
0.659 0.341 0.000
L28.0 Lichen simplex chronicus
0.658 0.342 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.657 0.343 0.000
I46 Cardiac arrest
0.657 0.343 0.000
S05.1 Contusion of eyeball and orbital tissues
0.656 0.344 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.655 0.345 0.000
H31 Other disorders of choroid
0.655 0.345 0.000
H30 Chorioretinal inflammation
0.655 0.345 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.655 0.345 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.655 0.345 0.000
M10 Gout
0.655 0.345 0.000
H74 Other disorders of middle ear and mastoid
0.655 0.345 0.000
N10-N16 Renal tubulo-interstitial diseases
0.654 0.346 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.653 0.346 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.653 0.346 0.000
B65-B83 Helminthiases
0.653 0.346 0.000
B50-B64 Protozoal diseases
0.653 0.346 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.653 0.346 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.653 0.346 0.000
A75-A79 Rickettsioses
0.653 0.346 0.000
A70-A74 Other diseases caused by chlamydiae
0.653 0.346 0.000
A65-A69 Other spirochaetal diseases
0.653 0.346 0.000
A20-A28 Certain zoonotic bacterial diseases
0.653 0.346 0.000
A15-A19 Tuberculosis
0.653 0.346 0.000
I42 Cardiomyopathy
0.653 0.347 0.000
J00 Acute nasopharyngitis [common cold]
0.653 0.347 0.000
I35.9 Aortic valve disorder, unspecified
0.652 0.347 0.000
I35.8 Other aortic valve disorders
0.652 0.347 0.000
H60 Otitis externa
0.652 0.348 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.651 0.349 0.000
E83.8 Other disorders of mineral metabolism
0.651 0.349 0.000
E83.3 Disorders of phosphorus metabolism
0.651 0.349 0.000
E83.2 Disorders of zinc metabolism
0.651 0.349 0.000
E83.0 Disorders of copper metabolism
0.651 0.349 0.000
I45.6 Preexcitation syndrome
0.650 0.349 0.000
A30-A49 Other bacterial diseases
0.651 0.349 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.650 0.350 0.000
L90.0 Lichen sclerosus et atrophicus
0.650 0.350 0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident
0.650 0.350 0.000
C34.0 Main bronchus
0.649 0.351 0.000
L27 Dermatitis due to substances taken internally
0.648 0.352 0.000
I60.8 Other subarachnoid haemorrhage
0.647 0.353 0.000
E20-E35 Disorders of other endocrine glands
0.646 0.354 0.000
E10.4 With neurological complications
0.646 0.354 0.000
Q89 Other congenital malformations, not elsewhere classified
0.646 0.354 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.645 0.355 0.000
W07 Fall involving chair
0.645 0.355 0.000
I06 Rheumatic aortic valve diseases
0.645 0.355 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.643 0.357 0.000
H73 Other disorders of tympanic membrane
0.643 0.357 0.000
T63 Toxic effect of contact with venomous animals
0.643 0.357 0.000
F17.9 Unspecified mental and behavioural disorder
0.643 0.357 0.000
F17.8 Other mental and behavioural disorders
0.643 0.357 0.000
F17.7 Residual and late-onset psychotic disorder
0.643 0.357 0.000
F17.6 Amnesic syndrome
0.643 0.357 0.000
F17.5 Psychotic disorder
0.643 0.357 0.000
F17.4 Withdrawal state with delirium
0.643 0.357 0.000
F17.3 Withdrawal state
0.643 0.357 0.000
F17.0 Acute intoxication
0.643 0.357 0.000
N61 Inflammatory disorders of breast
0.643 0.357 0.000
Y42.9 Other and unspecified hormone antagonists
0.643 0.357 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.643 0.357 0.000
Y42.4 Oral contraceptives
0.643 0.357 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.643 0.357 0.000
Y42.2 Antithyroid drugs
0.643 0.357 0.000
Y42.1 Thyroid hormones and substitutes
0.643 0.357 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.643 0.357 0.000
I77.8 Other specified disorders of arteries and arterioles
0.643 0.357 0.000
F43 Reaction to severe stress, and adjustment disorders
0.643 0.357 0.000
S22.2 Fracture of sternum
0.642 0.358 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.642 0.358 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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