TreeWAS – Variant ID: rs11964561

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
I30-I52 Other forms of heart disease	0.999	0.001
Chapter IX Diseases of the circulatory system	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
M20-M25 Other joint disorders	0.984	0.016
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.977	0.023
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.963	0.037
Chapter VI Diseases of the nervous system	0.960	0.040
M25 Other joint disorders, not elsewhere classified	0.959	0.041
I49 Other cardiac arrhythmias	0.952	0.048
I60-I69 Cerebrovascular diseases	0.944	0.056
I51 Complications and ill-defined descriptions of heart disease	0.936	0.064
M70-M79 Other soft tissue disorders	0.934	0.066
I49.5 Sick sinus syndrome	0.927	0.073
I35 Nonrheumatic aortic valve disorders	0.923	0.077
M25.7 Osteophyte	0.922	0.078
Chapter I Certain infectious and parasitic diseases	0.916	0.084
I42 Cardiomyopathy	0.910	0.090
M79 Other soft tissue disorders, not elsewhere classified	0.902	0.098
Chapter IV Endocrine, nutritional and metabolic diseases	0.901	0.099
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.900	0.100
I33 Acute and subacute endocarditis	0.899	0.101
I51.7 Cardiomegaly	0.899	0.101
I05-I09 Chronic rheumatic heart diseases	0.895	0.105
Chapter VIII Diseases of the ear and mastoid process	0.892	0.108
I63 Cerebral infarction	0.890	0.110
I45 Other conduction disorders	0.886	0.114
E10-E14 Diabetes mellitus	0.885	0.115
M05-M14 Inflammatory polyarthropathies	0.883	0.117
Chapter XX External causes of morbidity and mortality	0.883	0.117
S70-S79 Injuries to the hip and thigh	0.881	0.119
I38 Endocarditis, valve unspecified	0.879	0.121
M25.77 Osteophyte (Ankle and foot)	0.876	0.124
G70-G73 Diseases of myoneural junction and muscle	0.875	0.124
M35 Other systemic involvement of connective tissue	0.875	0.125
H65-H75 Diseases of middle ear and mastoid	0.873	0.127
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.871	0.129
G00-G09 Inflammatory diseases of the central nervous system	0.871	0.129
Chapter XV Pregnancy, childbirth and the puerperium	0.867	0.133
E11 Non-insulin-dependent diabetes mellitus	0.860	0.140
Q20-Q28 Congenital malformations of the circulatory system	0.858	0.142
B35-B49 Mycoses	0.857	0.143
M25.76 Osteophyte (Lower leg)	0.847	0.153
I05 Rheumatic mitral valve diseases	0.846	0.154
I35.1 Aortic (valve) insufficiency	0.837	0.163
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.836	0.164
M10 Gout	0.833	0.167
H65 Nonsuppurative otitis media	0.831	0.169
T93 Sequelae of injuries of lower limb	0.830	0.170
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.829	0.171
I33.0 Acute and subacute infective endocarditis	0.828	0.172
M65-M68 Disorders of synovium and tendon	0.827	0.173
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.822	0.178
I36 Nonrheumatic tricuspid valve disorders	0.822	0.178
M79.6 Pain in limb	0.820	0.180
M86-M90 Other osteopathies	0.820	0.180
M25.5 Pain in joint	0.818	0.182
O00-O08 Pregnancy with abortive outcome	0.812	0.188
G80-G83 Cerebral palsy and other paralytic syndromes	0.811	0.188
M24 Other specific joint derangements	0.811	0.189
G90-G99 Other disorders of the nervous system	0.808	0.192
Chapter V Mental and behavioural disorders	0.805	0.195
Y52 Agents primarily affecting the cardiovascular system	0.805	0.195
I34 Nonrheumatic mitral valve disorders	0.805	0.195
T66-T78 Other and unspecified effects of external causes	0.804	0.196
M34 Systemic sclerosis	0.803	0.197
I95-I99 Other and unspecified disorders of the circulatory system	0.802	0.198
Chapter XXII Codes for special purposes	0.801	0.199
I64 Stroke, not specified as haemorrhage or infarction	0.801	0.199
E11.4 With neurological complications	0.798	0.202
M10.9 Gout, unspecified	0.798	0.202
T20-T25 Burns and corrosions of external body surface, specified by site	0.797	0.203
M91-M94 Chondropathies	0.794	0.206
S72 Fracture of femur	0.793	0.207
I45.5 Other specified heart block	0.792	0.208
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.789	0.211
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.788	0.212
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.787	0.213
I49.3 Ventricular premature depolarisation	0.782	0.218
M35.3 Polymyalgia rheumatica	0.782	0.218
G06 Intracranial and intraspinal abscess and granuloma	0.777	0.223
Chapter VII Diseases of the eye and adnexa	0.776	0.224
I05.0 Mitral stenosis	0.775	0.225
T85 Complications of other internal prosthetic devices, implants and grafts	0.775	0.225
I46 Cardiac arrest	0.775	0.225
S10-S19 Injuries to the neck	0.775	0.225
Chapter XIV Diseases of the genitourinary system	0.773	0.227
E10 Insulin-dependent diabetes mellitus	0.772	0.228
M00-M03 Infectious arthropathies	0.769	0.231
B49 Unspecified mycosis	0.767	0.233
Q28 Other congenital malformations of circulatory system	0.766	0.234
M10.99 Gout, unspecified (Site unspecified)	0.763	0.237
H65.3 Chronic mucoid otitis media	0.761	0.239
G30-G32 Other degenerative diseases of the nervous system	0.760	0.240
I44 Atrioventricular and left bundle-branch block	0.759	0.241
H74 Other disorders of middle ear and mastoid	0.758	0.242
I49.8 Other specified cardiac arrhythmias	0.756	0.244
O03 Spontaneous abortion	0.755	0.245
Q50-Q56 Congenital malformations of genital organs	0.754	0.246
B37 Candidiasis	0.754	0.246
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.753	0.247
I35.9 Aortic valve disorder, unspecified	0.753	0.247
M25.51 Pain in joint (Shoulder region)	0.752	0.248
M79.67 Pain in limb (Ankle and foot)	0.751	0.249
I42.2 Other hypertrophic cardiomyopathy	0.751	0.249
M79.66 Pain in limb (Lower leg)	0.751	0.249
M79.7 Fibromyalgia	0.748	0.252
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.748	0.252
S50-S59 Injuries to the elbow and forearm	0.747	0.253
M79.8 Other specified soft tissue disorders	0.746	0.254
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.746	0.254
G71 Primary disorders of muscles	0.745	0.255
I51.6 Cardiovascular disease, unspecified	0.744	0.256
S60-S69 Injuries to the wrist and hand	0.743	0.257
B65-B83 Helminthiases	0.741	0.259
I69 Sequelae of cerebrovascular disease	0.740	0.260
G72 Other myopathies	0.739	0.261
Q38-Q45 Other congenital malformations of the digestive system	0.739	0.261
Q60-Q64 Congenital malformations of the urinary system	0.739	0.261
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.738	0.262
I42.0 Dilated cardiomyopathy	0.736	0.264
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.736	0.264
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.731	0.269
I49.9 Cardiac arrhythmia, unspecified	0.730	0.270
I62 Other nontraumatic intracranial haemorrhage	0.729	0.271
M60-M63 Disorders of muscles	0.728	0.271
M25.3 Other instability of joint	0.728	0.271
M25.8 Other specified joint disorders	0.727	0.273
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.726	0.274
T81 Complications of procedures, not elsewhere classified	0.726	0.274
T95 Sequelae of burns, corrosions and frostbite	0.725	0.275
E11.1 With ketoacidosis	0.723	0.277
N70-N77 Inflammatory diseases of female pelvic organs	0.722	0.278
I67 Other cerebrovascular diseases	0.720	0.280
G81 Hemiplegia	0.720	0.280
M25.0 Haemarthrosis	0.719	0.281
S20-S29 Injuries to the thorax	0.719	0.281
I42.9 Cardiomyopathy, unspecified	0.719	0.281
Q00-Q07 Congenital malformations of the nervous system	0.718	0.282
H65.2 Chronic serous otitis media	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.716	0.284
I48 Atrial fibrillation and flutter	0.716	0.284
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.284
I41 Myocarditis in diseases classified elsewhere	0.716	0.284
I40 Acute myocarditis	0.716	0.284
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.284
I32 Pericarditis in diseases classified elsewhere	0.716	0.284
I00-I02 Acute rheumatic fever	0.716	0.284
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.715	0.285
S72.0 Fracture of neck of femur	0.712	0.288
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.710	0.289
I95 Hypotension	0.710	0.290
H40-H42 Glaucoma	0.710	0.290
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.709	0.291
I45.9 Conduction disorder, unspecified	0.709	0.291
I37 Pulmonary valve disorders	0.709	0.291
I45.1 Other and unspecified right bundle-branch block	0.709	0.291
Y52.3 Coronary vasodilators, not elsewhere classified	0.708	0.292
M25.55 Pain in joint (Pelvic region and thigh)	0.707	0.293
E16 Other disorders of pancreatic internal secretion	0.707	0.293
N60-N64 Disorders of breast	0.706	0.294
E40-E46 Malnutrition	0.706	0.294
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.706	0.294
M33 Dermatopolymyositis	0.706	0.294
M32 Systemic lupus erythematosus	0.706	0.294
M30 Polyarteritis nodosa and related conditions	0.706	0.294
A50-A64 Infections with a predominantly sexual mode of transmission	0.704	0.296
T93.2 Sequelae of other fractures of lower limb	0.702	0.298
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.701	0.299
M23 Internal derangement of knee	0.700	0.300
T33-T35 Frostbite	0.700	0.300
T26-T28 Burns and corrosions confined to eye and internal organs	0.700	0.300
T00-T07 Injuries involving multiple body regions	0.700	0.300
I34.0 Mitral (valve) insufficiency	0.700	0.300
T91 Sequelae of injuries of neck and trunk	0.700	0.300
Q28.2 Arteriovenous malformation of cerebral vessels	0.700	0.300
T93.0 Sequelae of open wound of lower limb	0.700	0.300
G20-G26 Extrapyramidal and movement disorders	0.697	0.303
M21 Other acquired deformities of limbs	0.697	0.303
I35.8 Other aortic valve disorders	0.696	0.304
M77 Other enthesopathies	0.695	0.305
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.695	0.305
M79.5 Residual foreign body in soft tissue	0.695	0.305
Q80-Q89 Other congenital malformations	0.694	0.306
H69 Other disorders of Eustachian tube	0.694	0.306
N25-N29 Other disorders of kidney and ureter	0.693	0.307
B20-B24 Human immunodeficiency virus [HIV] disease	0.693	0.307
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.692	0.308
M86 Osteomyelitis	0.692	0.308
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.690	0.309
Q35-Q37 Cleft lip and cleft palate	0.690	0.309
Q30-Q34 Congenital malformations of the respiratory system	0.690	0.309
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.691	0.309
M67 Other disorders of synovium and tendon	0.689	0.311
I42.6 Alcoholic cardiomyopathy	0.689	0.311
T15-T19 Effects of foreign body entering through natural orifice	0.688	0.311
N62 Hypertrophy of breast	0.688	0.312
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.688	0.312
I05.1 Rheumatic mitral insufficiency	0.688	0.312
M25.2 Flail joint	0.688	0.312
M25.1 Fistula of joint	0.688	0.312
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.687	0.313
M25.6 Stiffness of joint, not elsewhere classified	0.687	0.313
B95-B98 Bacterial, viral and other infectious agents	0.686	0.314
E11.9 Without complications	0.685	0.315
O36 Maternal care for other known or suspected foetal problems	0.684	0.316
G04 Encephalitis, myelitis and encephalomyelitis	0.684	0.316
I49.2 Junctional premature depolarisation	0.682	0.318
S71 Open wound of hip and thigh	0.682	0.318
E20-E35 Disorders of other endocrine glands	0.682	0.318
I05.2 Mitral stenosis with insufficiency	0.681	0.318
M71 Other bursopathies	0.681	0.319
I51.4 Myocarditis, unspecified	0.681	0.319
Y45.1 Salicylates	0.680	0.320
M79.4 Hypertrophy of (infrapatellar) fat pad	0.680	0.320
O48 Prolonged pregnancy	0.680	0.320
E11.5 With peripheral circulatory complications	0.679	0.321
O03.9 Complete or unspecified, without complication	0.679	0.321
M76 Enthesopathies of lower limb, excluding foot	0.679	0.321
M75 Shoulder lesions	0.679	0.321
I49.1 Atrial premature depolarisation	0.677	0.323
I68 Cerebrovascular disorders in diseases classified elsewhere	0.676	0.323
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.676	0.323
I44.2 Atrioventricular block, complete	0.675	0.325
N73 Other female pelvic inflammatory diseases	0.675	0.325
M05 Seropositive rheumatoid arthritis	0.675	0.325
G06.2 Extradural and subdural abscess, unspecified	0.675	0.325
T86 Failure and rejection of transplanted organs and tissues	0.675	0.325
H71 Cholesteatoma of middle ear	0.674	0.326
E50-E64 Other nutritional deficiencies	0.673	0.327
A30-A49 Other bacterial diseases	0.673	0.327
T81.3 Disruption of operation wound, not elsewhere classified	0.672	0.328
I42.1 Obstructive hypertrophic cardiomyopathy	0.672	0.328
O04 Medical abortion	0.671	0.329
X58-X59 Accidental exposure to other and unspecified factors	0.671	0.329
I51.5 Myocardial degeneration	0.671	0.329
I51.3 Intracardiac thrombosis, not elsewhere classified	0.671	0.329
I51.2 Rupture of papillary muscle, not elsewhere classified	0.671	0.329
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.671	0.329
I51.0 Cardiac septal defect, acquired	0.671	0.329
O43 Placental disorders	0.671	0.329
M79.1 Myalgia	0.670	0.330
M73 Soft tissue disorders in diseases classified elsewhere	0.669	0.330
T79-T79 Certain early complications of trauma	0.669	0.331
M35.0 Sicca syndrome [Sjogren]	0.669	0.331
T93.9 Sequelae of unspecified injury of lower limb	0.668	0.332
Q23 Congenital malformations of aortic and mitral valves	0.668	0.332
S70 Superficial injury of hip and thigh	0.668	0.332
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.667	0.333
G70 Myasthenia gravis and other myoneural disorders	0.666	0.333
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.666	0.334
T88 Other complications of surgical and medical care, not elsewhere classified	0.666	0.334
G91 Hydrocephalus	0.665	0.335
O40 Polyhydramnios	0.664	0.336
M07 Psoriatic and enteropathic arthropathies	0.663	0.337
O41 Other disorders of amniotic fluid and membranes	0.663	0.337
T87 Complications peculiar to reattachment and amputation	0.662	0.337
T98 Sequelae of other and unspecified effects of external causes	0.662	0.338
H40 Glaucoma	0.662	0.338
M25.9 Joint disorder, unspecified	0.661	0.339
W50-W64 Exposure to animate mechanical forces	0.661	0.339
M25.79 Osteophyte (Site unspecified)	0.661	0.339
M25.73 Osteophyte (Forearm)	0.661	0.339
M25.72 Osteophyte (Upper arm)	0.661	0.339
M25.70 Osteophyte (Multiple sites)	0.661	0.339
S80-S89 Injuries to the knee and lower leg	0.661	0.339
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.661	0.339
H72 Perforation of tympanic membrane	0.660	0.340
M80-M85 Disorders of bone density and structure	0.660	0.340
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.659	0.341
M22 Disorders of patella	0.658	0.342
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.657	0.342
M24.5 Contracture of joint	0.657	0.343
B85-B89 Pediculosis, acariasis and other infestations	0.657	0.343
B50-B64 Protozoal diseases	0.657	0.343
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.657	0.343
A75-A79 Rickettsioses	0.657	0.343
A70-A74 Other diseases caused by chlamydiae	0.657	0.343
A65-A69 Other spirochaetal diseases	0.657	0.343
A20-A28 Certain zoonotic bacterial diseases	0.657	0.343
A15-A19 Tuberculosis	0.657	0.343
T85.2 Mechanical complication of intraocular lens	0.657	0.343
A80-A89 Viral infections of the central nervous system	0.656	0.343
G90 Disorders of autonomic nervous system	0.656	0.344
I95.9 Hypotension, unspecified	0.656	0.344
Y45.2 Propionic acid derivatives	0.656	0.344
O44 Placenta praevia	0.655	0.345
B15-B19 Viral hepatitis	0.655	0.345
M31 Other necrotising vasculopathies	0.655	0.345
S72.00 Fracture of neck of femur (closed)	0.654	0.346
B90-B94 Sequelae of infectious and parasitic diseases	0.654	0.346
G81.9 Hemiplegia, unspecified	0.654	0.346
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.654	0.346
E10.9 Without complications	0.653	0.347
I42.8 Other cardiomyopathies	0.653	0.347
I42.7 Cardiomyopathy due to drugs and other external agents	0.653	0.347
I42.5 Other restrictive cardiomyopathy	0.653	0.347
I42.4 Endocardial fibroelastosis	0.653	0.347
I42.3 Endomyocardial (eosinophilic) disease	0.653	0.347
S72.3 Fracture of shaft of femur	0.653	0.347
F50 Eating disorders	0.652	0.348
I31 Other diseases of pericardium	0.651	0.348
M25.78 Osteophyte (Other)	0.651	0.349
G03 Meningitis due to other and unspecified causes	0.650	0.350
Y86 Sequelae of other accidents	0.650	0.350
I61 Intracerebral haemorrhage	0.650	0.350
E10.8 With unspecified complications	0.649	0.351
M92 Other juvenile osteochondrosis	0.649	0.351
Y57 Other and unspecified drugs and medicaments	0.649	0.351
E16.2 Hypoglycaemia, unspecified	0.649	0.351
V80-V89 Other land transport accidents	0.649	0.351
I35.0 Aortic (valve) stenosis	0.648	0.352
V40-V49 Car occupant injured in transport accident	0.648	0.352
B99-B99 Other infectious diseases	0.647	0.352
E14 Unspecified diabetes mellitus	0.647	0.353
M79.9 Soft tissue disorder, unspecified	0.646	0.353
M79.3 Panniculitis, unspecified	0.646	0.353
M79.2 Neuralgia and neuritis, unspecified	0.646	0.353
T94 Sequelae of injuries involving multiple and unspecified body regions	0.645	0.355
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.645	0.355
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.645	0.355
I33.9 Acute endocarditis, unspecified	0.645	0.355
N73.6 Female pelvic peritoneal adhesions	0.645	0.355
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.644	0.356
I35.2 Aortic (valve) stenosis with insufficiency	0.644	0.356
I07 Rheumatic tricuspid valve diseases	0.644	0.356
H73 Other disorders of tympanic membrane	0.643	0.357
I09 Other rheumatic heart diseases	0.642	0.358
I06 Rheumatic aortic valve diseases	0.642	0.358
V20-V29 Motorcycle rider injured in transport accident	0.642	0.358
O03.4 Incomplete, without complication	0.642	0.358
T21 Burn and corrosion of trunk	0.641	0.359
Y52.4 Angiotensin-converting-enzyme inhibitors	0.641	0.359
O46 Antepartum haemorrhage, not elsewhere classified	0.641	0.359
E11.6 With other specified complications	0.641	0.359
M34.9 Systemic sclerosis, unspecified	0.639	0.361
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.638	0.361
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.638	0.361
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.638	0.361
H65.4 Other chronic nonsuppurative otitis media	0.638	0.362
M79.79 Fibromyalgia (Site unspecified)	0.638	0.362
T80 Complications following infusion, transfusion and therapeutic injection	0.637	0.362
T81.4 Infection following a procedure, not elsewhere classified	0.637	0.363
T78 Adverse effects, not elsewhere classified	0.637	0.363
Y60-Y69 Misadventures to patients during surgical and medical care	0.636	0.364
B25-B34 Other viral diseases	0.635	0.365
I45.8 Other specified conduction disorders	0.635	0.365
I45.4 Nonspecific intraventricular block	0.635	0.365
I45.3 Trifascicular block	0.635	0.365
I45.2 Bifascicular block	0.635	0.365
I45.0 Right fascicular block	0.635	0.365
T68 Hypothermia	0.635	0.365
E12 Malnutrition-related diabetes mellitus	0.635	0.365
T83.3 Mechanical complication of intra-uterine contraceptive device	0.634	0.366
F60-F69 Disorders of adult personality and behaviour	0.634	0.366
M14 Arthropathies in other diseases classified elsewhere	0.633	0.367
M12 Other specific arthropathies	0.633	0.367
M09 Juvenile arthritis in diseases classified elsewhere	0.633	0.367
M08 Juvenile arthritis	0.633	0.367
Y35-Y36 Legal intervention and operations of war	0.633	0.367
Y10-Y34 Event of undetermined intent	0.633	0.367
Y00-Y09 Assault	0.633	0.367
X85-X99 Assault	0.633	0.367
X50-X57 Overexertion, travel and privation	0.633	0.367
X30-X39 Exposure to forces of nature	0.633	0.367
X20-X29 Contact with venomous animals and plants	0.633	0.367
X10-X19 Contact with heat and hot substances	0.633	0.367
X00-X09 Exposure to smoke, fire and flames	0.633	0.367
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.633	0.367
W75-W84 Other accidental threats to breathing	0.633	0.367
W65-W74 Accidental drowning and submersion	0.633	0.367
V98-V99 Other and unspecified transport accidents	0.633	0.367
V95-V97 Air and space transport accidents	0.633	0.367
V90-V94 Water transport accidents	0.633	0.367
V70-V79 Bus occupant injured in transport accident	0.633	0.367
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.633	0.367
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.633	0.367
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.633	0.367
V01-V09 Pedestrian injured in transport accident	0.633	0.367
Y45.5 4-Aminophenol derivatives	0.632	0.368
S78 Traumatic amputation of hip and thigh	0.632	0.368
S77 Crushing injury of hip and thigh	0.632	0.368
S76 Injury of muscle and tendon at hip and thigh level	0.632	0.368
S75 Injury of blood vessels at hip and thigh level	0.632	0.368
S74 Injury of nerves at hip and thigh level	0.632	0.368
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.632	0.368
G06.1 Intraspinal abscess and granuloma	0.631	0.369
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.631	0.369
M70 Soft tissue disorders related to use, overuse and pressure	0.631	0.369
H40.0 Glaucoma suspect	0.628	0.372
I67.1 Cerebral aneurysm, nonruptured	0.628	0.372
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.628	0.372
Y45.0 Opioids and related analgesics	0.628	0.372
M35.9 Systemic involvement of connective tissue, unspecified	0.628	0.372
M35.8 Other specified systemic involvement of connective tissue	0.628	0.372
M35.7 Hypermobility syndrome	0.628	0.372
M35.6 Relapsing panniculitis [Weber-Christian]	0.628	0.372
M35.5 Multifocal fibrosclerosis	0.628	0.372
M35.4 Diffuse (eosinophilic) fasciitis	0.628	0.372
M35.2 Behcet's disease	0.628	0.372
M35.1 Other overlap syndromes	0.628	0.372
B37.0 Candidal stomatitis	0.627	0.373
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.627	0.373
E11.0 With coma	0.627	0.373
M02 Reactive arthropathies	0.626	0.374
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.626	0.374
H70 Mastoiditis and related conditions	0.626	0.374
H68 Eustachian salpingitis and obstruction	0.626	0.374
H67 Otitis media in diseases classified elsewhere	0.626	0.374
Q27 Other congenital malformations of peripheral vascular system	0.626	0.374
M25.74 Osteophyte (Hand)	0.625	0.374
O85-O92 Complications predominantly related to the puerperium	0.625	0.375
G71.0 Muscular dystrophy	0.625	0.375
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.624	0.376
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.624	0.376
G00 Bacterial meningitis, not elsewhere classified	0.624	0.376
G09 Sequelae of inflammatory diseases of central nervous system	0.624	0.376
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.624	0.376
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.624	0.376
G01 Meningitis in bacterial diseases classified elsewhere	0.624	0.376
M34.1 CR(E)ST syndrome	0.623	0.377
G72.0 Drug-induced myopathy	0.623	0.377
I30 Acute pericarditis	0.622	0.378
F40-F48 Neurotic, stress-related and somatoform disorders	0.622	0.378
E13 Other specified diabetes mellitus	0.622	0.378
N20-N23 Urolithiasis	0.622	0.378
H43-H45 Disorders of vitreous body and globe	0.621	0.379
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.621	0.379
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.620	0.380
F52 Sexual dysfunction, not caused by organic disorder or disease	0.620	0.380
Y45.8 Other analgesics and antipyretics	0.620	0.380
T90 Sequelae of injuries of head	0.620	0.380
I51.8 Other ill-defined heart diseases	0.620	0.380
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.618	0.382
M89 Other disorders of bone	0.618	0.382
B35 Dermatophytosis	0.618	0.382
E10.5 With peripheral circulatory complications	0.618	0.382
N80-N98 Noninflammatory disorders of female genital tract	0.617	0.383
I63.8 Other cerebral infarction	0.616	0.383
E11.8 With unspecified complications	0.616	0.383
E11.7 With multiple complications	0.616	0.383
M40-M43 Deforming dorsopathies	0.616	0.383
B80 Enterobiasis	0.616	0.384
G83 Other paralytic syndromes	0.615	0.385
Q26 Congenital malformations of great veins	0.615	0.385
Q25 Congenital malformations of great arteries	0.615	0.385
Q24 Other congenital malformations of heart	0.615	0.385
Q22 Congenital malformations of pulmonary and tricuspid valves	0.615	0.385
Q20 Congenital malformations of cardiac chambers and connexions	0.615	0.385
M10.94 Gout, unspecified (Hand)	0.615	0.385
M25.81 Other specified joint disorders (Shoulder region)	0.615	0.385
B48 Other mycoses, not elsewhere classified	0.614	0.385
B47 Mycetoma	0.614	0.385
B46 Zygomycosis	0.614	0.385
B45 Cryptococcosis	0.614	0.385
B43 Chromomycosis and phaeomycotic abscess	0.614	0.385
B42 Sporotrichosis	0.614	0.385
B41 Paracoccidioidomycosis	0.614	0.385
B40 Blastomycosis	0.614	0.385
B39 Histoplasmosis	0.614	0.385
B38 Coccidioidomycosis	0.614	0.385
B36 Other superficial mycoses	0.614	0.385
G93 Other disorders of brain	0.615	0.385
M65 Synovitis and tenosynovitis	0.613	0.387
H55-H59 Other disorders of eye and adnexa	0.612	0.388
H74.4 Polyp of middle ear	0.612	0.388
S40-S49 Injuries to the shoulder and upper arm	0.611	0.389
T23 Burn and corrosion of wrist and hand	0.609	0.391
N85 Other noninflammatory disorders of uterus, except cervix	0.608	0.392
S60 Superficial injury of wrist and hand	0.608	0.392
I05.8 Other mitral valve diseases	0.607	0.393
O30 Multiple gestation	0.606	0.394
M24.2 Disorder of ligament	0.606	0.394
U88 Agent resistant to multiple antibiotics	0.605	0.395
X60-X84 Intentional self-harm	0.605	0.395
O32 Maternal care for known or suspected malpresentation of foetus	0.604	0.395
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.604	0.396
X40-X49 Accidental poisoning by and exposure to noxious substances	0.603	0.397
M66 Spontaneous rupture of synovium and tendon	0.603	0.397
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.602	0.398
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.602	0.398
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.601	0.398
W00-W19 Falls	0.601	0.399
M25.4 Effusion of joint	0.601	0.399
S90-S99 Injuries to the ankle and foot	0.600	0.400
Y59 Other and unspecified vaccines and biological substances	0.599	0.401
Y58 Bacterial vaccines	0.599	0.401
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.599	0.401
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.599	0.401
Y53 Agents primarily affecting the gastro-intestinal system	0.599	0.401
Y50 Central nervous system stimulants, not elsewhere classified	0.599	0.401
Y49 Psychotropic drugs, not elsewhere classified	0.599	0.401
Y48 Anaesthetics and therapeutic gases	0.599	0.401
Y47 Sedatives, hypnotics and antianxiety drugs	0.599	0.401
Y46 Antiepileptics and anti-Parkinsonism drugs	0.599	0.401
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.599	0.401
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.599	0.401
E11.2 With renal complications	0.599	0.401
M24.0 Loose body in joint	0.599	0.401

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations