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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77869481
log Bayes Factor = 13.1447
Chromosome 3   position 191,374,294  (GRCh37) Explore rs77869481 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
M70-M79 Other soft tissue disorders
0.997 0.003 0.000
M75 Shoulder lesions
0.996 0.004 0.000
M75.4 Impingement syndrome of shoulder
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.990 0.010 0.000
E70-E90 Metabolic disorders
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.983 0.017 0.000
Chapter VII Diseases of the eye and adnexa
0.981 0.019 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.979 0.021 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.974 0.026 0.000
Chapter XXI Factors influencing health status and contact with health services
0.973 0.027 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.969 0.031 0.000
M20-M25 Other joint disorders
0.969 0.031 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
Chapter I Certain infectious and parasitic diseases
0.968 0.032 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.967 0.033 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.966 0.034 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.964 0.036 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.962 0.038 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.962 0.038 0.000
Chapter IX Diseases of the circulatory system
0.962 0.038 0.000
M45-M49 Spondylopathies
0.958 0.042 0.000
M35 Other systemic involvement of connective tissue
0.957 0.043 0.000
Z02 Examination and encounter for administrative purposes
0.954 0.046 0.000
L57.0 Actinic keratosis
0.953 0.047 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.952 0.048 0.000
H30-H36 Disorders of choroid and retina
0.951 0.049 0.000
M35.3 Polymyalgia rheumatica
0.949 0.051 0.000
S00-S09 Injuries to the head
0.949 0.051 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.948 0.052 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.946 0.054 0.000
R25 Abnormal involuntary movements
0.945 0.055 0.000
Z02.8 Other examinations for administrative purposes
0.944 0.056 0.000
M75.5 Bursitis of shoulder
0.942 0.058 0.000
H65-H75 Diseases of middle ear and mastoid
0.940 0.060 0.000
M75.1 Rotator cuff syndrome
0.936 0.064 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.933 0.067 0.000
Chapter V Mental and behavioural disorders
0.931 0.069 0.000
S00 Superficial injury of head
0.930 0.070 0.000
H40-H42 Glaucoma
0.927 0.073 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.927 0.073 0.000
E20-E35 Disorders of other endocrine glands
0.926 0.074 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.926 0.074 0.000
R50-R69 General symptoms and signs
0.924 0.076 0.000
M24 Other specific joint derangements
0.923 0.077 0.000
E86 Volume depletion
0.921 0.079 0.000
T92 Sequelae of injuries of upper limb
0.918 0.082 0.000
H90-H95 Other disorders of ear
0.911 0.089 0.000
M47 Spondylosis
0.909 0.091 0.000
O00-O08 Pregnancy with abortive outcome
0.906 0.094 0.000
E10-E14 Diabetes mellitus
0.905 0.095 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.904 0.096 0.000
I77 Other disorders of arteries and arterioles
0.903 0.097 0.000
R29.6 Tendency to fall, not elsewhere classified
0.901 0.099 0.000
R47-R49 Symptoms and signs involving speech and voice
0.900 0.100 0.000
R80 Isolated proteinuria
0.898 0.102 0.000
M47.9 Spondylosis, unspecified
0.896 0.104 0.000
I05-I09 Chronic rheumatic heart diseases
0.895 0.105 0.000
R25.1 Tremor, unspecified
0.893 0.107 0.000
H40 Glaucoma
0.888 0.112 0.000
S40-S49 Injuries to the shoulder and upper arm
0.888 0.112 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.880 0.120 0.000
H60-H62 Diseases of external ear
0.879 0.121 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.877 0.123 0.000
H40.9 Glaucoma, unspecified
0.876 0.124 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.875 0.125 0.000
R59 Enlarged lymph nodes
0.874 0.126 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.873 0.127 0.000
E10 Insulin-dependent diabetes mellitus
0.871 0.129 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.870 0.130 0.000
Y57 Other and unspecified drugs and medicaments
0.870 0.130 0.000
S00.8 Superficial injury of other parts of head
0.869 0.131 0.000
M80-M85 Disorders of bone density and structure
0.866 0.134 0.000
H43-H45 Disorders of vitreous body and globe
0.866 0.134 0.000
O03 Spontaneous abortion
0.865 0.135 0.000
Y52 Agents primarily affecting the cardiovascular system
0.863 0.137 0.000
I77.1 Stricture of artery
0.860 0.140 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.859 0.141 0.000
T90 Sequelae of injuries of head
0.852 0.148 0.000
M24.1 Other articular cartilage disorders
0.849 0.151 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.849 0.151 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.849 0.151 0.000
H65 Nonsuppurative otitis media
0.848 0.152 0.000
S60-S69 Injuries to the wrist and hand
0.843 0.157 0.000
R47 Speech disturbances, not elsewhere classified
0.840 0.160 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.839 0.161 0.000
E88 Other metabolic disorders
0.838 0.162 0.000
R53 Malaise and fatigue
0.834 0.166 0.000
H34 Retinal vascular occlusions
0.832 0.168 0.000
H90 Conductive and sensorineural hearing loss
0.829 0.171 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.828 0.172 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.828 0.172 0.000
A00-A09 Intestinal infectious diseases
0.827 0.173 0.000
O20 Haemorrhage in early pregnancy
0.824 0.176 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.823 0.177 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.822 0.178 0.000
M45 Ankylosing spondylitis
0.820 0.179 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.820 0.180 0.000
S00.1 Contusion of eyelid and periocular area
0.818 0.182 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
S80-S89 Injuries to the knee and lower leg
0.815 0.185 0.000
H73 Other disorders of tympanic membrane
0.812 0.188 0.000
E24 Cushing's syndrome
0.811 0.189 0.000
H33 Retinal detachments and breaks
0.811 0.189 0.000
M31 Other necrotising vasculopathies
0.809 0.191 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.808 0.192 0.000
E50-E64 Other nutritional deficiencies
0.808 0.192 0.000
I74 Arterial embolism and thrombosis
0.807 0.193 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.805 0.195 0.000
Y44 Agents primarily affecting blood constituents
0.804 0.196 0.000
M60-M63 Disorders of muscles
0.804 0.196 0.000
Y57.9 Drug or medicament, unspecified
0.803 0.197 0.000
I08 Multiple valve diseases
0.802 0.198 0.000
R54 Senility
0.802 0.198 0.000
R59.9 Enlarged lymph nodes, unspecified
0.800 0.200 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.800 0.200 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.800 0.200 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.799 0.201 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.798 0.202 0.000
H36 Retinal disorders in diseases classified elsewhere
0.798 0.202 0.000
M71 Other bursopathies
0.795 0.205 0.000
H74 Other disorders of middle ear and mastoid
0.791 0.209 0.000
H61 Other disorders of external ear
0.790 0.209 0.000
I78 Diseases of capillaries
0.790 0.210 0.000
R63 Symptoms and signs concerning food and fluid intake
0.789 0.211 0.000
I84 Haemorrhoids
0.788 0.212 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.787 0.213 0.000
B35-B49 Mycoses
0.787 0.213 0.000
E87.5 Hyperkalaemia
0.787 0.213 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.785 0.215 0.000
I84.9 Unspecified haemorrhoids without complication
0.785 0.215 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.785 0.215 0.000
S70-S79 Injuries to the hip and thigh
0.785 0.215 0.000
O03.4 Incomplete, without complication
0.785 0.215 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.784 0.216 0.000
E34 Other endocrine disorders
0.782 0.218 0.000
R47.0 Dysphasia and aphasia
0.781 0.219 0.000
I27 Other pulmonary heart diseases
0.781 0.219 0.000
H10-H13 Disorders of conjunctiva
0.779 0.221 0.000
O03.9 Complete or unspecified, without complication
0.778 0.222 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.778 0.222 0.000
H43 Disorders of vitreous body
0.777 0.223 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.776 0.224 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.776 0.224 0.000
A30-A49 Other bacterial diseases
0.775 0.225 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.775 0.225 0.000
L93 Lupus erythematosus
0.774 0.226 0.000
T93 Sequelae of injuries of lower limb
0.774 0.226 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.774 0.226 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.774 0.226 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.773 0.227 0.000
S43.0 Dislocation of shoulder joint
0.773 0.227 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.772 0.228 0.000
H65.3 Chronic mucoid otitis media
0.772 0.228 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.771 0.229 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.769 0.231 0.000
H92 Otalgia and effusion of ear
0.769 0.231 0.000
R59.1 Generalised enlarged lymph nodes
0.768 0.232 0.000
R87 Abnormal findings in specimens from female genital organs
0.768 0.232 0.000
L10-L14 Bullous disorders
0.766 0.234 0.000
E10.4 With neurological complications
0.762 0.238 0.000
M34 Systemic sclerosis
0.761 0.239 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.761 0.239 0.000
I71 Aortic aneurysm and dissection
0.760 0.240 0.000
M77 Other enthesopathies
0.760 0.240 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.760 0.240 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.759 0.241 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.757 0.243 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.757 0.243 0.000
I08.0 Disorders of both mitral and aortic valves
0.757 0.243 0.000
E27 Other disorders of adrenal gland
0.757 0.243 0.000
S00.3 Superficial injury of nose
0.756 0.244 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.756 0.244 0.000
M91-M94 Chondropathies
0.754 0.246 0.000
S00.0 Superficial injury of scalp
0.753 0.247 0.000
T92.1 Sequelae of fracture of arm
0.753 0.247 0.000
H31 Other disorders of choroid
0.752 0.247 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.752 0.248 0.000
S02 Fracture of skull and facial bones
0.752 0.248 0.000
B50-B64 Protozoal diseases
0.751 0.249 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.750 0.250 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.750 0.250 0.000
R63.4 Abnormal weight loss
0.749 0.251 0.000
S68 Traumatic amputation of wrist and hand
0.749 0.251 0.000
O02 Other abnormal products of conception
0.749 0.251 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.748 0.252 0.000
B99-B99 Other infectious diseases
0.748 0.252 0.000
B95-B98 Bacterial, viral and other infectious agents
0.748 0.252 0.000
R26 Abnormalities of gait and mobility
0.747 0.253 0.000
I27.0 Primary pulmonary hypertension
0.745 0.255 0.000
S90-S99 Injuries to the ankle and foot
0.745 0.255 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.745 0.255 0.000
X20-X29 Contact with venomous animals and plants
0.744 0.256 0.000
M46 Other inflammatory spondylopathies
0.744 0.256 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.743 0.257 0.000
I07 Rheumatic tricuspid valve diseases
0.743 0.257 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.742 0.258 0.000
O04 Medical abortion
0.742 0.258 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.740 0.260 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.740 0.260 0.000
I70 Atherosclerosis
0.740 0.260 0.000
Y45.0 Opioids and related analgesics
0.739 0.261 0.000
I73 Other peripheral vascular diseases
0.737 0.263 0.000
H72 Perforation of tympanic membrane
0.736 0.264 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.736 0.264 0.000
M24.2 Disorder of ligament
0.735 0.265 0.000
R60 Oedema, not elsewhere classified
0.733 0.267 0.000
R56 Convulsions, not elsewhere classified
0.733 0.267 0.000
H33.3 Retinal breaks without detachment
0.732 0.268 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.731 0.268 0.000
T59 Toxic effect of other gases, fumes and vapours
0.731 0.269 0.000
H90.2 Conductive hearing loss, unspecified
0.731 0.269 0.000
E24.9 Cushing's syndrome, unspecified
0.729 0.271 0.000
H35 Other retinal disorders
0.729 0.271 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.728 0.272 0.000
H61.2 Impacted cerumen
0.728 0.272 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.727 0.273 0.000
L50-L54 Urticaria and erythema
0.727 0.273 0.000
S00.7 Multiple superficial injuries of head
0.727 0.273 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.725 0.275 0.000
X50-X57 Overexertion, travel and privation
0.723 0.277 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.723 0.277 0.000
R82 Other abnormal findings in urine
0.722 0.277 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.722 0.278 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.722 0.278 0.000
H66 Suppurative and unspecified otitis media
0.722 0.278 0.000
T90.9 Sequelae of unspecified injury of head
0.722 0.278 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.722 0.278 0.000
H73.8 Other specified disorders of tympanic membrane
0.720 0.280 0.000
W50-W64 Exposure to animate mechanical forces
0.719 0.281 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.719 0.281 0.000
H65.2 Chronic serous otitis media
0.718 0.282 0.000
M85 Other disorders of bone density and structure
0.718 0.282 0.000
M86-M90 Other osteopathies
0.718 0.282 0.000
Y00-Y09 Assault
0.718 0.282 0.000
E88.2 Lipomatosis, not elsewhere classified
0.718 0.282 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I84.5 External haemorrhoids without complication
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
O23 Infections of genito-urinary tract in pregnancy
0.715 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.714 0.285 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.714 0.286 0.000
M75.8 Other shoulder lesions
0.714 0.286 0.000
M75.9 Shoulder lesion, unspecified
0.714 0.286 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.287 0.000
Z32 Pregnancy examination and test
0.713 0.287 0.000
H40.5 Glaucoma secondary to other eye disorders
0.713 0.287 0.000
E89.0 Postprocedural hypothyroidism
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
T91 Sequelae of injuries of neck and trunk
0.711 0.289 0.000
T92.0 Sequelae of open wound of upper limb
0.710 0.290 0.000
E10.3 With ophthalmic complications
0.710 0.290 0.000
E85 Amyloidosis
0.709 0.291 0.000
E84 Cystic fibrosis
0.709 0.291 0.000
E79 Disorders of purine and pyrimidine metabolism
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.709 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.709 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.709 0.291 0.000
E74 Other disorders of carbohydrate metabolism
0.709 0.291 0.000
E73 Lactose intolerance
0.709 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.709 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.709 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.709 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.709 0.291 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.708 0.292 0.000
R25.2 Cramp and spasm
0.708 0.292 0.000
Y45.1 Salicylates
0.707 0.293 0.000
H34.2 Other retinal artery occlusions
0.706 0.293 0.000
I77.0 Arteriovenous fistula, acquired
0.706 0.294 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.706 0.294 0.000
R81 Glycosuria
0.705 0.295 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.704 0.296 0.000
B25-B34 Other viral diseases
0.704 0.296 0.000
O85-O92 Complications predominantly related to the puerperium
0.703 0.297 0.000
A49 Bacterial infection of unspecified site
0.703 0.297 0.000
E10.6 With other specified complications
0.703 0.297 0.000
E26 Hyperaldosteronism
0.702 0.298 0.000
T98 Sequelae of other and unspecified effects of external causes
0.702 0.298 0.000
T95 Sequelae of burns, corrosions and frostbite
0.702 0.298 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.702 0.298 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.702 0.298 0.000
Y85 Sequelae of transport accidents
0.701 0.299 0.000
L80 Vitiligo
0.700 0.300 0.000
S05 Injury of eye and orbit
0.700 0.300 0.000
E87.7 Fluid overload
0.700 0.300 0.000
E10.9 Without complications
0.699 0.301 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.698 0.301 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.698 0.302 0.000
L58 Radiodermatitis
0.698 0.302 0.000
L55 Sunburn
0.698 0.302 0.000
T63 Toxic effect of contact with venomous animals
0.698 0.302 0.000
R68 Other general symptoms and signs
0.698 0.302 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.698 0.302 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.698 0.302 0.000
F30-F39 Mood [affective] disorders
0.698 0.302 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.697 0.303 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.697 0.303 0.000
Y40 Systemic antibiotics
0.696 0.303 0.000
M21 Other acquired deformities of limbs
0.696 0.304 0.000
L83 Acanthosis nigricans
0.696 0.304 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.695 0.305 0.000
Z10 Routine general health check-up of defined subpopulation
0.695 0.305 0.000
M84 Disorders of continuity of bone
0.694 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.305 0.000
M33 Dermatopolymyositis
0.694 0.305 0.000
M32 Systemic lupus erythematosus
0.694 0.305 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.305 0.000
R87.6 Abnormal cytological findings
0.694 0.306 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.694 0.306 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.694 0.306 0.000
B65-B83 Helminthiases
0.694 0.306 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.694 0.306 0.000
A75-A79 Rickettsioses
0.694 0.306 0.000
A70-A74 Other diseases caused by chlamydiae
0.694 0.306 0.000
A65-A69 Other spirochaetal diseases
0.694 0.306 0.000
A20-A28 Certain zoonotic bacterial diseases
0.694 0.306 0.000
A15-A19 Tuberculosis
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.694 0.306 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.693 0.307 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.693 0.307 0.000
L57.5 Actinic granuloma
0.693 0.307 0.000
L57.4 Cutis laxa senilis
0.693 0.307 0.000
L57.3 Poikiloderma of Civatte
0.693 0.307 0.000
L57.2 Cutis rhomboidalis nuchae
0.693 0.307 0.000
L57.1 Actinic reticuloid
0.693 0.307 0.000
F99-F99 Unspecified mental disorder
0.692 0.307 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.692 0.308 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.692 0.308 0.000
R61 Hyperhidrosis
0.692 0.308 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.691 0.309 0.000
H43.1 Vitreous haemorrhage
0.691 0.309 0.000
Y44.2 Anticoagulants
0.691 0.309 0.000
L84 Corns and callosities
0.691 0.309 0.000
Z33 Pregnant state, incidental
0.690 0.310 0.000
R29.4 Clicking hip
0.690 0.310 0.000
R29.3 Abnormal posture
0.690 0.310 0.000
R29.2 Abnormal reflex
0.690 0.310 0.000
R29.1 Meningismus
0.690 0.310 0.000
R29.0 Tetany
0.690 0.310 0.000
Y59 Other and unspecified vaccines and biological substances
0.690 0.310 0.000
Y58 Bacterial vaccines
0.690 0.310 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.690 0.310 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.690 0.310 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.690 0.310 0.000
Y48 Anaesthetics and therapeutic gases
0.690 0.310 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.690 0.310 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.690 0.310 0.000
I00-I02 Acute rheumatic fever
0.690 0.310 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.689 0.310 0.000
H90.5 Sensorineural hearing loss, unspecified
0.689 0.311 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.689 0.311 0.000
H36.0 Diabetic retinopathy
0.689 0.311 0.000
M65-M68 Disorders of synovium and tendon
0.688 0.312 0.000
E23 Hypofunction and other disorders of pituitary gland
0.687 0.313 0.000
M49 Spondylopathies in diseases classified elsewhere
0.687 0.313 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.687 0.313 0.000
E40-E46 Malnutrition
0.686 0.314 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.686 0.314 0.000
M35.8 Other specified systemic involvement of connective tissue
0.686 0.314 0.000
M35.7 Hypermobility syndrome
0.686 0.314 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.686 0.314 0.000
M35.5 Multifocal fibrosclerosis
0.686 0.314 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.686 0.314 0.000
M35.2 Behcet's disease
0.686 0.314 0.000
M35.1 Other overlap syndromes
0.686 0.314 0.000
M82 Osteoporosis in diseases classified elsewhere
0.686 0.314 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.686 0.314 0.000
Q80-Q89 Other congenital malformations
0.684 0.316 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.684 0.316 0.000
Z02.9 Examination for administrative purposes, unspecified
0.684 0.316 0.000
Z02.7 Issue of medical certificate
0.684 0.316 0.000
Z02.6 Examination for insurance purposes
0.684 0.316 0.000
Z02.5 Examination for participation in sport
0.684 0.316 0.000
Z02.4 Examination for driving licence
0.684 0.316 0.000
Z02.3 Examination for recruitment to armed forces
0.684 0.316 0.000
Z02.2 Examination for admission to residential institution
0.684 0.316 0.000
Z02.1 Pre-employment examination
0.684 0.316 0.000
Z02.0 Examination for admission to educational institution
0.684 0.316 0.000
I84.2 Internal haemorrhoids without complication
0.683 0.317 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.682 0.318 0.000
H30 Chorioretinal inflammation
0.682 0.318 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.682 0.318 0.000
S08 Traumatic amputation of part of head
0.680 0.320 0.000
S07 Crushing injury of head
0.680 0.320 0.000
S04 Injury of cranial nerves
0.680 0.320 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.680 0.320 0.000
S89 Other and unspecified injuries of lower leg
0.680 0.320 0.000
E87.4 Mixed disorder of acid-base balance
0.679 0.320 0.000
R20 Disturbances of skin sensation
0.679 0.320 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.679 0.321 0.000
E29 Testicular dysfunction
0.679 0.321 0.000
M35.0 Sicca syndrome [Sjogren]
0.679 0.321 0.000
E87.2 Acidosis
0.679 0.321 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.679 0.321 0.000
F80-F89 Disorders of psychological development
0.678 0.322 0.000
R25.0 Abnormal head movements
0.677 0.323 0.000
E10.2 With renal complications
0.677 0.323 0.000
I05 Rheumatic mitral valve diseases
0.677 0.323 0.000
F06.7 Mild cognitive disorder
0.677 0.323 0.000
T90.5 Sequelae of intracranial injury
0.677 0.323 0.000
A80-A89 Viral infections of the central nervous system
0.676 0.324 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.676 0.324 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.676 0.324 0.000
I78.1 Naevus, nonneoplastic
0.676 0.324 0.000
S81 Open wound of lower leg
0.676 0.324 0.000
R94 Abnormal results of function studies
0.676 0.324 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.674 0.326 0.000
H70 Mastoiditis and related conditions
0.674 0.326 0.000
H68 Eustachian salpingitis and obstruction
0.674 0.326 0.000
H67 Otitis media in diseases classified elsewhere
0.674 0.326 0.000
L89 Decubitus ulcer
0.674 0.326 0.000
M50-M54 Other dorsopathies
0.674 0.326 0.000
H69 Other disorders of Eustachian tube
0.674 0.326 0.000
A08 Viral and other specified intestinal infections
0.673 0.327 0.000
M31.6 Other giant cell arteritis
0.672 0.328 0.000
H34.8 Other retinal vascular occlusions
0.671 0.329 0.000
M80 Osteoporosis with pathological fracture
0.670 0.330 0.000
L91 Hypertrophic disorders of skin
0.670 0.330 0.000
T51 Toxic effect of alcohol
0.669 0.331 0.000
B15-B19 Viral hepatitis
0.669 0.331 0.000
S67 Crushing injury of wrist and hand
0.668 0.332 0.000
F60-F69 Disorders of adult personality and behaviour
0.668 0.332 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.668 0.332 0.000
F70-F79 Mental retardation
0.668 0.332 0.000
S64 Injury of nerves at wrist and hand level
0.668 0.332 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.667 0.333 0.000
V10-V19 Pedal cyclist injured in transport accident
0.667 0.333 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.667 0.333 0.000
S00.5 Superficial injury of lip and oral cavity
0.666 0.333 0.000
S00.4 Superficial injury of ear
0.666 0.333 0.000
L93.0 Discoid lupus erythematosus
0.666 0.334 0.000
H52 Disorders of refraction and accommodation
0.666 0.334 0.000
Z35 Supervision of high-risk pregnancy
0.665 0.335 0.000
R25.3 Fasciculation
0.665 0.335 0.000
H42 Glaucoma in diseases classified elsewhere
0.665 0.335 0.000
M75.2 Bicipital tendinitis
0.664 0.336 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.664 0.336 0.000
E32 Diseases of thymus
0.664 0.336 0.000
E31 Polyglandular dysfunction
0.664 0.336 0.000
E30 Disorders of puberty, not elsewhere classified
0.664 0.336 0.000
E25 Adrenogenital disorders
0.664 0.336 0.000
E20 Hypoparathyroidism
0.664 0.336 0.000
M62 Other disorders of muscle
0.664 0.336 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.664 0.336 0.000
L94 Other localised connective tissue disorders
0.664 0.336 0.000
L87 Transepidermal elimination disorders
0.664 0.336 0.000
L88 Pyoderma gangrenosum
0.664 0.336 0.000
L86 Keratoderma in diseases classified elsewhere
0.664 0.336 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.662 0.338 0.000
R62 Lack of expected normal physiological development
0.662 0.338 0.000
R64 Cachexia
0.662 0.338 0.000
R58 Haemorrhage, not elsewhere classified
0.662 0.338 0.000
M24.9 Joint derangement, unspecified
0.662 0.338 0.000
M24.7 Protrusio acetabuli
0.662 0.338 0.000
M24.6 Ankylosis of joint
0.662 0.338 0.000
M24.5 Contracture of joint
0.662 0.338 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.662 0.338 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.662 0.338 0.000
E80.4 Gilbert's syndrome
0.662 0.338 0.000
E87.3 Alkalosis
0.660 0.340 0.000
T66-T78 Other and unspecified effects of external causes
0.660 0.340 0.000
V80-V89 Other land transport accidents
0.660 0.340 0.000
H33.4 Traction detachment of retina
0.660 0.340 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.659 0.340 0.000
S69 Other and unspecified injuries of wrist and hand
0.659 0.340 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.658 0.342 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.658 0.342 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.658 0.342 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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