TreeWAS – Variant ID: rs114889417

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
I30-I52 Other forms of heart disease	0.999	0.001
H53-H54 Visual disturbances and blindness	0.994	0.006
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.994	0.006
E10 Insulin-dependent diabetes mellitus	0.994	0.006
H53 Visual disturbances	0.991	0.009
Chapter XV Pregnancy, childbirth and the puerperium	0.991	0.009
I50 Heart failure	0.986	0.014
I50.9 Heart failure, unspecified	0.984	0.016
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.983	0.017
E14 Unspecified diabetes mellitus	0.978	0.022
I70-I79 Diseases of arteries, arterioles and capillaries	0.978	0.022
S60-S69 Injuries to the wrist and hand	0.978	0.022
H53.2 Diplopia	0.976	0.024
T81 Complications of procedures, not elsewhere classified	0.975	0.025
Chapter VI Diseases of the nervous system	0.972	0.028
O48 Prolonged pregnancy	0.965	0.035
I51 Complications and ill-defined descriptions of heart disease	0.965	0.035
E20-E35 Disorders of other endocrine glands	0.965	0.035
E14.9 Without complications	0.962	0.038
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.960	0.040
I05-I09 Chronic rheumatic heart diseases	0.960	0.040
E10.9 Without complications	0.958	0.042
T85 Complications of other internal prosthetic devices, implants and grafts	0.949	0.051
H53.8 Other visual disturbances	0.948	0.052
T36-T50 Poisoning by drugs, medicaments and biological substances	0.948	0.052
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.944	0.056
H43-H45 Disorders of vitreous body and globe	0.941	0.059
T81.3 Disruption of operation wound, not elsewhere classified	0.938	0.062
I42 Cardiomyopathy	0.933	0.067
I31 Other diseases of pericardium	0.931	0.069
I08 Multiple valve diseases	0.929	0.071
E00-E07 Disorders of thyroid gland	0.924	0.076
H49 Paralytic strabismus	0.913	0.087
I78 Diseases of capillaries	0.908	0.092
S20-S29 Injuries to the thorax	0.908	0.092
H43 Disorders of vitreous body	0.905	0.095
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.902	0.098
Chapter XX External causes of morbidity and mortality	0.901	0.099
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.899	0.101
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.889	0.111
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.886	0.114
E03 Other hypothyroidism	0.885	0.115
G90-G99 Other disorders of the nervous system	0.881	0.119
Chapter I Certain infectious and parasitic diseases	0.878	0.122
E10.1 With ketoacidosis	0.877	0.123
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.877	0.123
I74 Arterial embolism and thrombosis	0.871	0.129
I08.0 Disorders of both mitral and aortic valves	0.868	0.132
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.867	0.133
E10.3 With ophthalmic complications	0.866	0.134
G40-G47 Episodic and paroxysmal disorders	0.866	0.134
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.864	0.136
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.860	0.140
I31.3 Pericardial effusion (noninflammatory)	0.859	0.141
S90-S99 Injuries to the ankle and foot	0.859	0.141
E11 Non-insulin-dependent diabetes mellitus	0.857	0.143
E03.9 Hypothyroidism, unspecified	0.853	0.147
H43.8 Other disorders of vitreous body	0.850	0.150
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.850	0.150
I42.9 Cardiomyopathy, unspecified	0.849	0.151
I51.6 Cardiovascular disease, unspecified	0.847	0.153
H10-H13 Disorders of conjunctiva	0.847	0.153
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.846	0.154
S40-S49 Injuries to the shoulder and upper arm	0.846	0.154
S68 Traumatic amputation of wrist and hand	0.843	0.157
A30-A49 Other bacterial diseases	0.839	0.161
S61 Open wound of wrist and hand	0.838	0.162
S66 Injury of muscle and tendon at wrist and hand level	0.838	0.162
I51.8 Other ill-defined heart diseases	0.836	0.164
I44 Atrioventricular and left bundle-branch block	0.836	0.164
Chapter XII Diseases of the skin and subcutaneous tissue	0.829	0.171
H55-H59 Other disorders of eye and adnexa	0.826	0.174
E16 Other disorders of pancreatic internal secretion	0.826	0.174
I78.1 Naevus, nonneoplastic	0.825	0.175
O36 Maternal care for other known or suspected foetal problems	0.821	0.179
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.819	0.181
E27 Other disorders of adrenal gland	0.816	0.184
H30-H36 Disorders of choroid and retina	0.816	0.184
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.814	0.186
O34 Maternal care for known or suspected abnormality of pelvic organs	0.812	0.188
S62 Fracture at wrist and hand level	0.811	0.189
H53.9 Visual disturbance, unspecified	0.811	0.189
O42 Premature rupture of membranes	0.807	0.193
I38 Endocarditis, valve unspecified	0.805	0.195
I51.9 Heart disease, unspecified	0.804	0.196
H49.0 Third [oculomotor] nerve palsy	0.803	0.197
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.800	0.200
S22 Fracture of rib(s), sternum and thoracic spine	0.798	0.202
E21.3 Hyperparathyroidism, unspecified	0.797	0.203
L00-L08 Infections of the skin and subcutaneous tissue	0.794	0.206
I71 Aortic aneurysm and dissection	0.794	0.206
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.794	0.206
T85.2 Mechanical complication of intraocular lens	0.793	0.207
Chapter XXII Codes for special purposes	0.792	0.208
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.791	0.209
I08.2 Disorders of both aortic and tricuspid valves	0.791	0.209
O44 Placenta praevia	0.790	0.210
I42.0 Dilated cardiomyopathy	0.789	0.211
G45 Transient cerebral ischaemic attacks and related syndromes	0.789	0.211
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.788	0.212
T81.4 Infection following a procedure, not elsewhere classified	0.787	0.213
Chapter XIV Diseases of the genitourinary system	0.786	0.214
H18 Other disorders of cornea	0.786	0.214
H43.1 Vitreous haemorrhage	0.785	0.215
T20-T25 Burns and corrosions of external body surface, specified by site	0.785	0.215
O80-O84 Delivery	0.782	0.218
S61.9 Open wound of wrist and hand, part unspecified	0.782	0.218
G91 Hydrocephalus	0.781	0.219
H50 Other strabismus	0.781	0.219
G47 Sleep disorders	0.780	0.220
G35-G37 Demyelinating diseases of the central nervous system	0.779	0.221
O40 Polyhydramnios	0.778	0.222
I95-I99 Other and unspecified disorders of the circulatory system	0.778	0.222
Q38-Q45 Other congenital malformations of the digestive system	0.777	0.223
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.776	0.224
S60 Superficial injury of wrist and hand	0.775	0.225
H20 Iridocyclitis	0.775	0.225
N99-N99 Other disorders of the genitourinary system	0.774	0.226
H49.2 Sixth [abducent] nerve palsy	0.773	0.227
I36 Nonrheumatic tricuspid valve disorders	0.771	0.229
E10.4 With neurological complications	0.770	0.230
G80-G83 Cerebral palsy and other paralytic syndromes	0.769	0.231
T88 Other complications of surgical and medical care, not elsewhere classified	0.768	0.232
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.768	0.232
N17-N19 Renal failure	0.768	0.232
H49.9 Paralytic strabismus, unspecified	0.767	0.233
E10.2 With renal complications	0.766	0.234
L03 Cellulitis	0.766	0.234
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.765	0.235
I05 Rheumatic mitral valve diseases	0.764	0.236
L03.3 Cellulitis of trunk	0.763	0.237
I72 Other aneurysm	0.762	0.238
E11.3 With ophthalmic complications	0.760	0.240
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.760	0.240
S42 Fracture of shoulder and upper arm	0.760	0.240
G45.9 Transient cerebral ischaemic attack, unspecified	0.760	0.240
I74.5 Embolism and thrombosis of iliac artery	0.759	0.241
H21 Other disorders of iris and ciliary body	0.759	0.241
N99.3 Prolapse of vaginal vault after hysterectomy	0.759	0.241
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.758	0.242
E11.4 With neurological complications	0.758	0.242
G90 Disorders of autonomic nervous system	0.757	0.243
I78.0 Hereditary haemorrhagic telangiectasia	0.756	0.244
T86 Failure and rejection of transplanted organs and tissues	0.755	0.245
T42.4 Benzodiazepines	0.754	0.246
O43 Placental disorders	0.754	0.246
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.753	0.247
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.752	0.248
I31.9 Disease of pericardium, unspecified	0.752	0.248
E20 Hypoparathyroidism	0.752	0.248
E04 Other non-toxic goitre	0.750	0.250
T43.0 Tricyclic and tetracyclic antidepressants	0.750	0.250
H53.4 Visual field defects	0.749	0.251
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.747	0.253
T90 Sequelae of injuries of head	0.747	0.253
S92 Fracture of foot, except ankle	0.747	0.253
G61 Inflammatory polyneuropathy	0.746	0.254
G00-G09 Inflammatory diseases of the central nervous system	0.746	0.254
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.744	0.256
T43.2 Other and unspecified antidepressants	0.743	0.257
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.742	0.258
I77 Other disorders of arteries and arterioles	0.742	0.258
W20-W49 Exposure to inanimate mechanical forces	0.741	0.259
H16 Keratitis	0.740	0.260
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.740	0.260
E21.0 Primary hyperparathyroidism	0.738	0.262
S27 Injury of other and unspecified intrathoracic organs	0.736	0.264
N17 Acute renal failure	0.735	0.265
X20-X29 Contact with venomous animals and plants	0.735	0.265
E28 Ovarian dysfunction	0.735	0.265
E16.2 Hypoglycaemia, unspecified	0.733	0.267
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.733	0.267
I60-I69 Cerebrovascular diseases	0.733	0.267
T81.7 Vascular complications following a procedure, not elsewhere classified	0.733	0.267
T81.9 Unspecified complication of procedure	0.732	0.268
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.729	0.271
H46-H48 Disorders of optic nerve and visual pathways	0.728	0.272
I44.7 Left bundle-branch block, unspecified	0.728	0.272
N18 Chronic renal failure	0.727	0.273
S10-S19 Injuries to the neck	0.727	0.273
A41 Other septicaemia	0.726	0.274
E24 Cushing's syndrome	0.725	0.274
G62 Other polyneuropathies	0.725	0.275
I33 Acute and subacute endocarditis	0.720	0.280
S62.5 Fracture of thumb	0.719	0.281
O30 Multiple gestation	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.716	0.284
I48 Atrial fibrillation and flutter	0.716	0.284
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.284
I41 Myocarditis in diseases classified elsewhere	0.716	0.284
I40 Acute myocarditis	0.716	0.284
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.284
I37 Pulmonary valve disorders	0.716	0.284
I32 Pericarditis in diseases classified elsewhere	0.716	0.284
A46 Erysipelas	0.716	0.284
E29 Testicular dysfunction	0.716	0.284
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.716	0.284
H52 Disorders of refraction and accommodation	0.716	0.284
G63 Polyneuropathy in diseases classified elsewhere	0.715	0.285
E23 Hypofunction and other disorders of pituitary gland	0.714	0.286
O36.8 Maternal care for other specified foetal problems	0.713	0.287
T87 Complications peculiar to reattachment and amputation	0.712	0.287
E10.8 With unspecified complications	0.712	0.288
E10.7 With multiple complications	0.712	0.288
E10.6 With other specified complications	0.712	0.288
E10.0 With coma	0.712	0.288
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.712	0.288
H10 Conjunctivitis	0.712	0.288
H36 Retinal disorders in diseases classified elsewhere	0.711	0.289
H53.6 Night blindness	0.711	0.289
H53.5 Colour vision deficiencies	0.711	0.289
H53.3 Other disorders of binocular vision	0.711	0.289
O85-O92 Complications predominantly related to the puerperium	0.711	0.289
E10.5 With peripheral circulatory complications	0.710	0.290
H57 Other disorders of eye and adnexa	0.709	0.291
O60-O75 Complications of labour and delivery	0.709	0.291
A49 Bacterial infection of unspecified site	0.708	0.292
O41 Other disorders of amniotic fluid and membranes	0.708	0.292
S61.8 Open wound of other parts of wrist and hand	0.707	0.293
E14.3 With ophthalmic complications	0.707	0.293
O20-O29 Other maternal disorders predominantly related to pregnancy	0.706	0.294
G47.3 Sleep apnoea	0.705	0.295
Q80-Q89 Other congenital malformations	0.705	0.295
O45 Premature separation of placenta [abruptio placentae]	0.705	0.295
O35 Maternal care for known or suspected foetal abnormality and damage	0.705	0.295
O33 Maternal care for known or suspected disproportion	0.705	0.295
O31 Complications specific to multiple gestation	0.705	0.295
I60 Subarachnoid haemorrhage	0.704	0.296
G93 Other disorders of brain	0.704	0.296
E11.2 With renal complications	0.704	0.296
N00-N08 Glomerular diseases	0.703	0.297
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.703	0.297
T92 Sequelae of injuries of upper limb	0.703	0.297
G20-G26 Extrapyramidal and movement disorders	0.703	0.297
N17.9 Acute renal failure, unspecified	0.702	0.298
I50.0 Congestive heart failure	0.702	0.298
X50-X57 Overexertion, travel and privation	0.701	0.299
E14.8 With unspecified complications	0.701	0.299
E14.7 With multiple complications	0.701	0.299
E14.6 With other specified complications	0.701	0.299
E14.5 With peripheral circulatory complications	0.701	0.299
E14.4 With neurological complications	0.701	0.299
E14.2 Withrenal complications	0.701	0.299
E14.1 With ketoacidosis	0.701	0.299
E14.0 With coma	0.701	0.299
S65 Injury of blood vessels at wrist and hand level	0.701	0.299
T83.0 Mechanical complication of urinary (indwelling) catheter	0.701	0.299
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.700	0.300
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.699	0.301
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.699	0.301
T79-T79 Certain early complications of trauma	0.697	0.303
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.696	0.303
E27.4 Other and unspecified adrenocortical insufficiency	0.696	0.304
E16.0 Drug-induced hypoglycaemia without coma	0.695	0.305
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.694	0.306
E13 Other specified diabetes mellitus	0.694	0.306
L02 Cutaneous abscess, furuncle and carbuncle	0.693	0.307
I51.5 Myocardial degeneration	0.692	0.308
I51.4 Myocarditis, unspecified	0.692	0.308
I51.3 Intracardiac thrombosis, not elsewhere classified	0.692	0.308
I51.2 Rupture of papillary muscle, not elsewhere classified	0.692	0.308
I51.0 Cardiac septal defect, acquired	0.692	0.308
E35 Disorders of endocrine glands in diseases classified elsewhere	0.692	0.308
E34 Other endocrine disorders	0.692	0.308
E32 Diseases of thymus	0.692	0.308
E31 Polyglandular dysfunction	0.692	0.308
E30 Disorders of puberty, not elsewhere classified	0.692	0.308
E26 Hyperaldosteronism	0.692	0.308
E25 Adrenogenital disorders	0.692	0.308
S64 Injury of nerves at wrist and hand level	0.692	0.308
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.692	0.308
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.691	0.309
T46 Poisoning by agents primarily affecting the cardiovascular system	0.691	0.309
G91.9 Hydrocephalus, unspecified	0.690	0.310
Q60-Q64 Congenital malformations of the urinary system	0.690	0.310
H51 Other disorders of binocular movement	0.689	0.311
I09 Other rheumatic heart diseases	0.688	0.312
I06 Rheumatic aortic valve diseases	0.688	0.312
T15-T19 Effects of foreign body entering through natural orifice	0.688	0.312
S20 Superficial injury of thorax	0.687	0.312
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.687	0.313
W50-W64 Exposure to animate mechanical forces	0.685	0.315
O36.0 Maternal care for rhesus isoimmunisation	0.684	0.316
O34.2 Maternal care due to uterine scar from previous surgery	0.684	0.316
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.682	0.318
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.682	0.318
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.681	0.319
I47 Paroxysmal tachycardia	0.681	0.319
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.681	0.319
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.681	0.319
S60.9 Superficial injury of wrist and hand, unspecified	0.680	0.320
H18.5 Hereditary corneal dystrophies	0.680	0.320
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.679	0.320
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.679	0.320
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.679	0.320
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.679	0.320
T41 Poisoning by anaesthetics and therapeutic gases	0.679	0.320
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.679	0.320
T36 Poisoning by systemic antibiotics	0.679	0.320
G35 Multiple sclerosis	0.678	0.322
H53.1 Subjective visual disturbances	0.678	0.322
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.677	0.323
H17 Corneal scars and opacities	0.677	0.323
H15 Disorders of sclera	0.677	0.323
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.675	0.325
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.675	0.325
S22.3 Fracture of rib	0.675	0.325
I70 Atherosclerosis	0.675	0.325
Y60-Y69 Misadventures to patients during surgical and medical care	0.674	0.326
I51.7 Cardiomegaly	0.674	0.326
A80-A89 Viral infections of the central nervous system	0.674	0.326
I42.2 Other hypertrophic cardiomyopathy	0.673	0.327
T80 Complications following infusion, transfusion and therapeutic injection	0.672	0.327
O94-O99 Other obstetric conditions, not elsewhere classified	0.671	0.328
Q38 Other congenital malformations of tongue, mouth and pharynx	0.670	0.330
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.670	0.330
I42.8 Other cardiomyopathies	0.669	0.331
I42.7 Cardiomyopathy due to drugs and other external agents	0.669	0.331
I42.6 Alcoholic cardiomyopathy	0.669	0.331
I42.5 Other restrictive cardiomyopathy	0.669	0.331
I42.4 Endocardial fibroelastosis	0.669	0.331
I42.3 Endomyocardial (eosinophilic) disease	0.669	0.331
I31.8 Other specified diseases of pericardium	0.667	0.333
I31.2 Haemopericardium, not elsewhere classified	0.667	0.333
I31.1 Chronic constrictive pericarditis	0.667	0.333
I31.0 Chronic adhesive pericarditis	0.667	0.333
S46 Injury of muscle and tendon at shoulder and upper arm level	0.667	0.333
I08.8 Other multiple valve diseases	0.666	0.333
I08.9 Multiple valve disease, unspecified	0.666	0.334
I44.3 Other and unspecified atrioventricular block	0.666	0.334
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.665	0.335
G30-G32 Other degenerative diseases of the nervous system	0.665	0.335
E07 Other disorders of thyroid	0.664	0.336
Y84.8 Other medical procedures	0.663	0.337
O82 Single delivery by Caesarean section	0.663	0.337
A00-A09 Intestinal infectious diseases	0.663	0.337
H50.2 Vertical strabismus	0.662	0.338
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.662	0.338
E00 Congenital iodine-deficiency syndrome	0.662	0.338
E02 Subclinical iodine-deficiency hypothyroidism	0.662	0.338
X60-X84 Intentional self-harm	0.662	0.338
H33 Retinal detachments and breaks	0.662	0.338
E03.8 Other specified hypothyroidism	0.661	0.339
E06 Thyroiditis	0.660	0.339
E04.2 Non-toxic multinodular goitre	0.660	0.340
N18.0 End-stage renal disease	0.660	0.340
V40-V49 Car occupant injured in transport accident	0.659	0.341
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.658	0.342
E11.1 With ketoacidosis	0.656	0.344
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.656	0.344
O16 Unspecified maternal hypertension	0.656	0.344
I42.1 Obstructive hypertrophic cardiomyopathy	0.656	0.344
G96 Other disorders of central nervous system	0.655	0.345
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.655	0.345
H49.8 Other paralytic strabismus	0.655	0.345
H49.4 Progressive external ophthalmoplegia	0.655	0.345
H49.3 Total (external) ophthalmoplegia	0.655	0.345
H49.1 Fourth [trochlear] nerve palsy	0.655	0.345
G70-G73 Diseases of myoneural junction and muscle	0.654	0.346
S69 Other and unspecified injuries of wrist and hand	0.653	0.346
O32 Maternal care for known or suspected malpresentation of foetus	0.653	0.347
T91 Sequelae of injuries of neck and trunk	0.653	0.347
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.652	0.348
H11 Other disorders of conjunctiva	0.651	0.349
I78.9 Disease of capillaries, unspecified	0.651	0.349
I78.8 Other diseases of capillaries	0.651	0.349
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.651	0.349
S26 Injury of heart	0.651	0.349
S25 Injury of blood vessels of thorax	0.651	0.349
S24 Injury of nerves and spinal cord at thorax level	0.651	0.349
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.651	0.349
S21 Open wound of thorax	0.651	0.349
E65-E68 Obesity and other hyperalimentation	0.650	0.350
B15-B19 Viral hepatitis	0.649	0.351
H43.9 Disorder of vitreous body, unspecified	0.649	0.351
H43.2 Crystalline deposits in vitreous body	0.649	0.351
H43.0 Vitreous prolapse	0.649	0.351
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.647	0.353
Q35-Q37 Cleft lip and cleft palate	0.647	0.353
Q30-Q34 Congenital malformations of the respiratory system	0.647	0.353
G61.0 Guillain-Barre syndrome	0.646	0.354
Y35-Y36 Legal intervention and operations of war	0.646	0.354
Y10-Y34 Event of undetermined intent	0.646	0.354
Y00-Y09 Assault	0.646	0.354
X85-X99 Assault	0.646	0.354
X58-X59 Accidental exposure to other and unspecified factors	0.646	0.354
X30-X39 Exposure to forces of nature	0.646	0.354
X10-X19 Contact with heat and hot substances	0.646	0.354
X00-X09 Exposure to smoke, fire and flames	0.646	0.354
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.646	0.354
W75-W84 Other accidental threats to breathing	0.646	0.354
W65-W74 Accidental drowning and submersion	0.646	0.354
V98-V99 Other and unspecified transport accidents	0.646	0.354
V95-V97 Air and space transport accidents	0.646	0.354
V90-V94 Water transport accidents	0.646	0.354
V70-V79 Bus occupant injured in transport accident	0.646	0.354
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.646	0.354
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.646	0.354
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.646	0.354
V01-V09 Pedestrian injured in transport accident	0.646	0.354
G44 Other headache syndromes	0.646	0.354
G82 Paraplegia and tetraplegia	0.645	0.355
H43.3 Other vitreous opacities	0.645	0.355
E15 Nondiabetic hypoglycaemic coma	0.644	0.356
L10-L14 Bullous disorders	0.644	0.356
E40-E46 Malnutrition	0.643	0.356
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.643	0.357
T94 Sequelae of injuries involving multiple and unspecified body regions	0.643	0.357
S92.0 Fracture of calcaneus	0.641	0.359
S29 Other and unspecified injuries of thorax	0.641	0.359
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.640	0.360
B35-B49 Mycoses	0.638	0.362
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.638	0.362
S22.4 Multiple fractures of ribs	0.637	0.363
E21.5 Disorder of parathyroid gland, unspecified	0.637	0.363
E21.4 Other specified disorders of parathyroid gland	0.637	0.363
E21.2 Other hyperparathyroidism	0.637	0.363
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.637	0.363
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.637	0.363
H36.0 Diabetic retinopathy	0.636	0.364
G60 Hereditary and idiopathic neuropathy	0.636	0.364
G64 Other disorders of peripheral nervous system	0.636	0.364
O36.6 Maternal care for excessive foetal growth	0.635	0.365
S42.0 Fracture of clavicle	0.635	0.365
S62.50 Fracture of thumb (closed)	0.635	0.365
O64 Obstructed labour due to malposition and malpresentation of foetus	0.634	0.366
E03.5 Myxoedema coma	0.634	0.366
E03.4 Atrophy of thyroid (acquired)	0.634	0.366
E03.3 Postinfectious hypothyroidism	0.634	0.366
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.634	0.366
E03.1 Congenital hypothyroidism without goitre	0.634	0.366
E03.0 Congenital hypothyroidism with diffuse goitre	0.634	0.366
E11.6 With other specified complications	0.633	0.367
A40 Streptococcal septicaemia	0.633	0.367
V80-V89 Other land transport accidents	0.632	0.368
H44 Disorders of globe	0.632	0.368
G94 Other disorders of brain in diseases classified elsewhere	0.632	0.368
G98 Other disorders of nervous system, not elsewhere classified	0.632	0.368
G92 Toxic encephalopathy	0.632	0.368
Q00-Q07 Congenital malformations of the nervous system	0.632	0.368
L03.0 Cellulitis of finger and toe	0.631	0.369
G93.9 Disorder of brain, unspecified	0.631	0.369
S41 Open wound of shoulder and upper arm	0.631	0.369
S91 Open wound of ankle and foot	0.630	0.370
H55 Nystagmus and other irregular eye movements	0.630	0.370
B99-B99 Other infectious diseases	0.630	0.370
B85-B89 Pediculosis, acariasis and other infestations	0.630	0.370
B50-B64 Protozoal diseases	0.630	0.370
B20-B24 Human immunodeficiency virus [HIV] disease	0.630	0.370
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.630	0.370
A75-A79 Rickettsioses	0.630	0.370
A70-A74 Other diseases caused by chlamydiae	0.630	0.370
A65-A69 Other spirochaetal diseases	0.630	0.370
A20-A28 Certain zoonotic bacterial diseases	0.630	0.370
A15-A19 Tuberculosis	0.630	0.370
H21.5 Other adhesions and disruptions of iris and ciliary body	0.630	0.370
E22 Hyperfunction of pituitary gland	0.628	0.372
G62.8 Other specified polyneuropathies	0.628	0.372
E27.9 Disorder of adrenal gland, unspecified	0.627	0.373
G90.9 Disorder of autonomic nervous system, unspecified	0.627	0.373
S67 Crushing injury of wrist and hand	0.626	0.374
G99 Other disorders of nervous system in diseases classified elsewhere	0.626	0.374
N18.9 Chronic renal failure, unspecified	0.625	0.375
I74.9 Embolism and thrombosis of unspecified artery	0.625	0.375
I74.8 Embolism and thrombosis of other arteries	0.625	0.375
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.625	0.375
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.625	0.375
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.625	0.375
I74.0 Embolism and thrombosis of abdominal aorta	0.625	0.375
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.624	0.376
W00-W19 Falls	0.624	0.376
I72.3 Aneurysm of iliac artery	0.623	0.376
A41.9 Septicaemia, unspecified	0.623	0.377
S42.4 Fracture of lower end of humerus	0.622	0.378
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.622	0.378
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.622	0.378
T42.5 Mixed antiepileptics, not elsewhere classified	0.622	0.378
T42.3 Barbiturates	0.622	0.378
T42.2 Succinimides and oxazolidinediones	0.622	0.378
T42.1 Iminostilbenes	0.622	0.378
T42.0 Hydantoin derivatives	0.622	0.378
T83.1 Mechanical complication of other urinary devices and implants	0.622	0.378
X40-X49 Accidental poisoning by and exposure to noxious substances	0.621	0.378
G46 Vascular syndromes of brain in cerebrovascular diseases	0.621	0.379
G41 Status epilepticus	0.621	0.379
H53.0 Amblyopia ex anopsia	0.621	0.379
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.620	0.380
G80 Infantile cerebral palsy	0.620	0.380

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations