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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs59218290
log Bayes Factor = 15.3723
Chromosome 11   position 131,807,633  (GRCh37) Explore rs59218290 on Ensembl!
Variant rs59218290 is part of Cluster X0106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
N95 Menopausal and other perimenopausal disorders
0.993 0.007 0.000
Z51 Other medical care
0.992 0.008 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.990 0.010 0.000
Z51.2 Other chemotherapy
0.982 0.018 0.000
Chapter II Neoplasms
0.979 0.021 0.000
O60-O75 Complications of labour and delivery
0.977 0.023 0.000
N17-N19 Renal failure
0.977 0.023 0.000
N30-N39 Other diseases of urinary system
0.973 0.027 0.000
Chapter IX Diseases of the circulatory system
0.970 0.030 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.962 0.038 0.000
N19 Unspecified renal failure
0.962 0.038 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.959 0.041 0.000
L20-L30 Dermatitis and eczema
0.958 0.042 0.000
N95.0 Postmenopausal bleeding
0.957 0.043 0.000
N39 Other disorders of urinary system
0.956 0.044 0.000
N95.2 Postmenopausal atrophic vaginitis
0.955 0.045 0.000
D50-D53 Nutritional anaemias
0.955 0.045 0.000
N39.0 Urinary tract infection, site not specified
0.952 0.048 0.000
Chapter VIII Diseases of the ear and mastoid process
0.948 0.052 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.940 0.060 0.000
Z46 Fitting and adjustment of other devices
0.940 0.060 0.000
N88 Other noninflammatory disorders of cervix uteri
0.939 0.061 0.000
D50 Iron deficiency anaemia
0.931 0.069 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.927 0.073 0.000
Z50 Care involving use of rehabilitation procedures
0.925 0.075 0.000
D50.9 Iron deficiency anaemia, unspecified
0.921 0.079 0.000
I60-I69 Cerebrovascular diseases
0.914 0.086 0.000
L30 Other dermatitis
0.912 0.088 0.000
I05-I09 Chronic rheumatic heart diseases
0.911 0.089 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.911 0.089 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.910 0.090 0.000
Chapter VII Diseases of the eye and adnexa
0.908 0.092 0.000
N89 Other noninflammatory disorders of vagina
0.906 0.094 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.902 0.098 0.000
Z48 Other surgical follow-up care
0.899 0.101 0.000
O72 Postpartum haemorrhage
0.895 0.105 0.000
H65-H75 Diseases of middle ear and mastoid
0.894 0.106 0.000
C34 Malignant neoplasm of bronchus and lung
0.890 0.110 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.889 0.111 0.000
Z50.1 Other physical therapy
0.889 0.111 0.000
O63 Long labour
0.888 0.112 0.000
Z46.6 Fitting and adjustment of urinary device
0.888 0.112 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.886 0.114 0.000
L40-L45 Papulosquamous disorders
0.884 0.116 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.883 0.117 0.000
S60-S69 Injuries to the wrist and hand
0.882 0.118 0.000
D68 Other coagulation defects
0.881 0.119 0.000
N25-N29 Other disorders of kidney and ureter
0.879 0.121 0.000
L30.9 Dermatitis, unspecified
0.879 0.121 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.877 0.123 0.000
H30-H36 Disorders of choroid and retina
0.877 0.123 0.000
S80-S89 Injuries to the knee and lower leg
0.876 0.124 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.868 0.132 0.000
D69 Purpura and other haemorrhagic conditions
0.866 0.134 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.863 0.137 0.000
Z43 Attention to artificial openings
0.861 0.139 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.858 0.142 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.857 0.143 0.000
Z47 Other orthopaedic follow-up care
0.854 0.146 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.853 0.147 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.850 0.150 0.000
N84 Polyp of female genital tract
0.846 0.154 0.000
S00-S09 Injuries to the head
0.845 0.155 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.843 0.157 0.000
O42 Premature rupture of membranes
0.840 0.160 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.839 0.161 0.000
N93 Other abnormal uterine and vaginal bleeding
0.838 0.162 0.000
Chapter XX External causes of morbidity and mortality
0.835 0.165 0.000
D60-D64 Aplastic and other anaemias
0.834 0.166 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.833 0.167 0.000
N10-N16 Renal tubulo-interstitial diseases
0.832 0.168 0.000
Z48.8 Other specified surgical follow-up care
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.828 0.172 0.000
M45-M49 Spondylopathies
0.827 0.173 0.000
Z52 Donors of organs and tissues
0.827 0.173 0.000
S70-S79 Injuries to the hip and thigh
0.823 0.177 0.000
O72.1 Other immediate postpartum haemorrhage
0.820 0.180 0.000
N87 Dysplasia of cervix uteri
0.816 0.184 0.000
C34.9 Bronchus or lung, unspecified
0.816 0.184 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.813 0.187 0.000
I08 Multiple valve diseases
0.809 0.191 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.808 0.192 0.000
H90-H95 Other disorders of ear
0.805 0.195 0.000
L40 Psoriasis
0.805 0.195 0.000
I60 Subarachnoid haemorrhage
0.802 0.198 0.000
H35 Other retinal disorders
0.799 0.201 0.000
M50-M54 Other dorsopathies
0.797 0.203 0.000
Z39 Postpartum care and examination
0.795 0.204 0.000
N88.2 Stricture and stenosis of cervix uteri
0.794 0.206 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.794 0.206 0.000
Z49 Care involving dialysis
0.793 0.207 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.793 0.207 0.000
E10-E14 Diabetes mellitus
0.792 0.208 0.000
S20-S29 Injuries to the thorax
0.790 0.210 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.790 0.210 0.000
S80 Superficial injury of lower leg
0.786 0.214 0.000
Z51.8 Other specified medical care
0.786 0.214 0.000
C91 Lymphoid leukaemia
0.784 0.216 0.000
N60-N64 Disorders of breast
0.782 0.218 0.000
H73 Other disorders of tympanic membrane
0.779 0.221 0.000
L27 Dermatitis due to substances taken internally
0.779 0.221 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
H65 Nonsuppurative otitis media
0.777 0.223 0.000
O63.1 Prolonged second stage (of labour)
0.776 0.224 0.000
C60-C63 Malignant neoplasms of male genital organs
0.776 0.224 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.773 0.227 0.000
D45 Polycythaemia vera
0.770 0.230 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.768 0.232 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.768 0.232 0.000
N97 Female infertility
0.767 0.233 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.767 0.233 0.000
C92 Myeloid leukaemia
0.767 0.233 0.000
D00-D09 In situ neoplasms
0.766 0.234 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.766 0.234 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.765 0.235 0.000
I07 Rheumatic tricuspid valve diseases
0.765 0.235 0.000
C34.1 Upper lobe, bronchus or lung
0.765 0.235 0.000
I63 Cerebral infarction
0.764 0.236 0.000
M48 Other spondylopathies
0.764 0.236 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.762 0.238 0.000
D68.2 Hereditary deficiency of other clotting factors
0.762 0.238 0.000
H36 Retinal disorders in diseases classified elsewhere
0.761 0.238 0.000
N39.9 Disorder of urinary system, unspecified
0.757 0.243 0.000
C90.0 Multiple myeloma
0.756 0.244 0.000
Z29 Need for other prophylactic measures
0.756 0.244 0.000
O36 Maternal care for other known or suspected foetal problems
0.756 0.244 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.755 0.245 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.753 0.247 0.000
I61 Intracerebral haemorrhage
0.753 0.247 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.753 0.247 0.000
N99-N99 Other disorders of the genitourinary system
0.753 0.247 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.751 0.249 0.000
C81 Hodgkin's disease
0.751 0.249 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.751 0.249 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.749 0.250 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.749 0.251 0.000
Z35 Supervision of high-risk pregnancy
0.749 0.251 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.748 0.251 0.000
Chapter XXII Codes for special purposes
0.748 0.252 0.000
N18 Chronic renal failure
0.746 0.254 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.746 0.254 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.745 0.255 0.000
M47 Spondylosis
0.744 0.256 0.000
H34 Retinal vascular occlusions
0.744 0.256 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.743 0.257 0.000
E20-E35 Disorders of other endocrine glands
0.743 0.257 0.000
T79-T79 Certain early complications of trauma
0.743 0.257 0.000
N95.1 Menopausal and female climacteric states
0.743 0.257 0.000
O00-O08 Pregnancy with abortive outcome
0.742 0.258 0.000
D68.9 Coagulation defect, unspecified
0.739 0.261 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.736 0.264 0.000
D80-D89 Certain disorders involving the immune mechanism
0.735 0.265 0.000
N60 Benign mammary dysplasia
0.735 0.265 0.000
Chapter I Certain infectious and parasitic diseases
0.734 0.266 0.000
Z51.1 Chemotherapy session for neoplasm
0.733 0.267 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.732 0.268 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.732 0.268 0.000
L29 Pruritus
0.732 0.268 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.731 0.269 0.000
N86 Erosion and ectropion of cervix uteri
0.731 0.269 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.731 0.269 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.728 0.272 0.000
O63.9 Long labour, unspecified
0.728 0.272 0.000
I20-I25 Ischaemic heart diseases
0.726 0.274 0.000
H72 Perforation of tympanic membrane
0.726 0.274 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.725 0.275 0.000
N00-N08 Glomerular diseases
0.725 0.275 0.000
O73 Retained placenta and membranes, without haemorrhage
0.724 0.276 0.000
I05 Rheumatic mitral valve diseases
0.723 0.277 0.000
L08 Other local infections of skin and subcutaneous tissue
0.723 0.277 0.000
Z46.8 Fitting and adjustment of other specified devices
0.722 0.278 0.000
Z22 Carrier of infectious disease
0.720 0.280 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.719 0.280 0.000
M48.0 Spinal stenosis
0.718 0.282 0.000
N13 Obstructive and reflux uropathy
0.718 0.282 0.000
M50 Cervical disk disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
Z54 Convalescence
0.716 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
H43-H45 Disorders of vitreous body and globe
0.716 0.284 0.000
N90.5 Atrophy of vulva
0.715 0.285 0.000
L28 Lichen simplex chronicus and prurigo
0.714 0.285 0.000
D55-D59 Haemolytic anaemias
0.714 0.286 0.000
N28.1 Cyst of kidney, acquired
0.714 0.286 0.000
E70-E90 Metabolic disorders
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.713 0.287 0.000
Z51.0 Radiotherapy session
0.713 0.287 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.713 0.287 0.000
L60-L75 Disorders of skin appendages
0.713 0.287 0.000
L40.9 Psoriasis, unspecified
0.713 0.287 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.712 0.288 0.000
N95.3 States associated with artificial menopause
0.712 0.288 0.000
Z51.9 Medical care, unspecified
0.711 0.289 0.000
Z51.6 Desensitisation to allergens
0.711 0.289 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.711 0.289 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.711 0.289 0.000
L10-L14 Bullous disorders
0.710 0.290 0.000
Z43.3 Attention to colostomy
0.709 0.291 0.000
O62 Abnormalities of forces of labour
0.709 0.291 0.000
Chapter VI Diseases of the nervous system
0.708 0.292 0.000
S01 Open wound of head
0.708 0.292 0.000
C34.3 Lower lobe, bronchus or lung
0.708 0.292 0.000
W20-W49 Exposure to inanimate mechanical forces
0.707 0.293 0.000
E10 Insulin-dependent diabetes mellitus
0.707 0.293 0.000
H35.3 Degeneration of macula and posterior pole
0.706 0.294 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.705 0.295 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.704 0.296 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
Z39.0 Care and examination immediately after delivery
0.703 0.297 0.000
Z52.4 Kidney donor
0.703 0.297 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.702 0.298 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.702 0.298 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.702 0.298 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.702 0.298 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.298 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.702 0.298 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.702 0.298 0.000
S02 Fracture of skull and facial bones
0.701 0.299 0.000
O74 Complications of anaesthesia during labour and delivery
0.701 0.299 0.000
O71 Other obstetric trauma
0.701 0.299 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.701 0.299 0.000
O66 Other obstructed labour
0.701 0.299 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.701 0.299 0.000
O61 Failed induction of labour
0.701 0.299 0.000
O60 Preterm delivery
0.701 0.299 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.700 0.299 0.000
Z42 Follow-up care involving plastic surgery
0.700 0.300 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.700 0.300 0.000
N37 Urethral disorders in diseases classified elsewhere
0.698 0.302 0.000
N36 Other disorders of urethra
0.698 0.302 0.000
N34 Urethritis and urethral syndrome
0.698 0.302 0.000
N33 Bladder disorders in diseases classified elsewhere
0.698 0.302 0.000
L03 Cellulitis
0.697 0.303 0.000
I99 Other and unspecified disorders of circulatory system
0.697 0.303 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.697 0.303 0.000
S90-S99 Injuries to the ankle and foot
0.697 0.303 0.000
H73.8 Other specified disorders of tympanic membrane
0.696 0.304 0.000
N39.4 Other specified urinary incontinence
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.695 0.304 0.000
Chapter XI Diseases of the digestive system
0.695 0.305 0.000
O80-O84 Delivery
0.694 0.306 0.000
S80.9 Superficial injury of lower leg, unspecified
0.694 0.306 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.694 0.306 0.000
O42.9 Premature rupture of membranes, unspecified
0.692 0.308 0.000
I30-I52 Other forms of heart disease
0.692 0.308 0.000
D64 Other anaemias
0.692 0.308 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.690 0.310 0.000
O45 Premature separation of placenta [abruptio placentae]
0.690 0.310 0.000
O44 Placenta praevia
0.690 0.310 0.000
O43 Placental disorders
0.690 0.310 0.000
O41 Other disorders of amniotic fluid and membranes
0.690 0.310 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.690 0.310 0.000
O33 Maternal care for known or suspected disproportion
0.690 0.310 0.000
O31 Complications specific to multiple gestation
0.690 0.310 0.000
O30 Multiple gestation
0.690 0.310 0.000
O40 Polyhydramnios
0.690 0.310 0.000
H40-H42 Glaucoma
0.689 0.311 0.000
D69.6 Thrombocytopenia, unspecified
0.688 0.311 0.000
N93.0 Postcoital and contact bleeding
0.688 0.311 0.000
S64 Injury of nerves at wrist and hand level
0.688 0.312 0.000
D67 Hereditary factor IX deficiency
0.688 0.312 0.000
D66 Hereditary factor VIII deficiency
0.688 0.312 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.688 0.312 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.687 0.313 0.000
L25 Unspecified contact dermatitis
0.687 0.313 0.000
L24 Irritant contact dermatitis
0.687 0.313 0.000
L23 Allergic contact dermatitis
0.687 0.313 0.000
L21 Seborrhoeic dermatitis
0.687 0.313 0.000
L20 Atopic dermatitis
0.687 0.313 0.000
L26 Exfoliative dermatitis
0.687 0.313 0.000
L22 Diaper [napkin] dermatitis
0.687 0.313 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.687 0.313 0.000
Z33 Pregnant state, incidental
0.687 0.313 0.000
S72 Fracture of femur
0.687 0.313 0.000
Z47.8 Other specified orthopaedic follow-up care
0.686 0.314 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.686 0.314 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.686 0.314 0.000
N39.2 Orthostatic proteinuria, unspecified
0.685 0.314 0.000
N39.1 Persistent proteinuria, unspecified
0.685 0.314 0.000
D53 Other nutritional anaemias
0.684 0.315 0.000
D52 Folate deficiency anaemia
0.684 0.315 0.000
H91 Other hearing loss
0.684 0.316 0.000
O48 Prolonged pregnancy
0.683 0.317 0.000
Z43.2 Attention to ileostomy
0.682 0.318 0.000
O34.1 Maternal care for tumour of corpus uteri
0.680 0.320 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.680 0.320 0.000
N32 Other disorders of bladder
0.680 0.320 0.000
I50 Heart failure
0.680 0.320 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.680 0.320 0.000
T66-T78 Other and unspecified effects of external causes
0.679 0.320 0.000
N10 Acute tubulo-interstitial nephritis
0.679 0.321 0.000
Z48.9 Surgical follow-up care, unspecified
0.679 0.321 0.000
H36.0 Diabetic retinopathy
0.679 0.321 0.000
N80 Endometriosis
0.679 0.321 0.000
S32 Fracture of lumbar spine and pelvis
0.678 0.322 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.677 0.323 0.000
D68.8 Other specified coagulation defects
0.676 0.324 0.000
N84.0 Polyp of corpus uteri
0.676 0.324 0.000
S40-S49 Injuries to the shoulder and upper arm
0.676 0.324 0.000
M47.9 Spondylosis, unspecified
0.675 0.325 0.000
E50-E64 Other nutritional deficiencies
0.674 0.326 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.674 0.326 0.000
C95 Leukaemia of unspecified cell type
0.674 0.326 0.000
C94 Other leukaemias of specified cell type
0.674 0.326 0.000
C93 Monocytic leukaemia
0.674 0.326 0.000
C88 Malignant immunoproliferative diseases
0.674 0.326 0.000
C86 Other specified types of T/NK-cell lymphoma
0.674 0.326 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.674 0.326 0.000
I67 Other cerebrovascular diseases
0.674 0.326 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.674 0.326 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.674 0.326 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.674 0.326 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.674 0.326 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.674 0.326 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.674 0.326 0.000
Z46.1 Fitting and adjustment of hearing aid
0.674 0.326 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.674 0.326 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.673 0.327 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.673 0.327 0.000
N88.3 Incompetence of cervix uteri
0.673 0.327 0.000
N88.1 Old laceration of cervix uteri
0.673 0.327 0.000
N88.0 Leukoplakia of cervix uteri
0.673 0.327 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.673 0.327 0.000
C91.1 Chronic lymphocytic leukaemia
0.672 0.328 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.672 0.328 0.000
H71 Cholesteatoma of middle ear
0.671 0.329 0.000
K55-K64 Other diseases of intestines
0.670 0.330 0.000
M54 Dorsalgia
0.668 0.332 0.000
D50.1 Sideropenic dysphagia
0.668 0.332 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.668 0.332 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.668 0.332 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.667 0.332 0.000
N92 Excessive, frequent and irregular menstruation
0.666 0.334 0.000
Z34 Supervision of normal pregnancy
0.665 0.335 0.000
E16 Other disorders of pancreatic internal secretion
0.665 0.335 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.665 0.335 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.665 0.335 0.000
C32 Malignant neoplasm of larynx
0.665 0.335 0.000
C31 Malignant neoplasm of accessory sinuses
0.665 0.335 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.665 0.335 0.000
C37 Malignant neoplasm of thymus
0.665 0.335 0.000
C33 Malignant neoplasm of trachea
0.665 0.335 0.000
M80-M85 Disorders of bone density and structure
0.664 0.336 0.000
M40-M43 Deforming dorsopathies
0.664 0.336 0.000
Z50.6 Orthoptic training
0.663 0.337 0.000
Z50.5 Speech therapy
0.663 0.337 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.663 0.337 0.000
Z50.3 Drug rehabilitation
0.663 0.337 0.000
Z50.2 Alcohol rehabilitation
0.663 0.337 0.000
O63.0 Prolonged first stage (of labour)
0.663 0.337 0.000
M48.06 Spinal stenosis (Lumbar region)
0.663 0.337 0.000
N84.1 Polyp of cervix uteri
0.663 0.337 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.662 0.338 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.661 0.339 0.000
I07.1 Tricuspid insufficiency
0.661 0.339 0.000
E86 Volume depletion
0.661 0.339 0.000
N94.1 Dyspareunia
0.660 0.340 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.655 0.345 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.655 0.345 0.000
I62 Other nontraumatic intracranial haemorrhage
0.655 0.345 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.655 0.345 0.000
C79 Secondary malignant neoplasm of other sites
0.655 0.345 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.654 0.346 0.000
L30.8 Other specified dermatitis
0.654 0.346 0.000
L30.5 Pityriasis alba
0.654 0.346 0.000
L30.4 Erythema intertrigo
0.654 0.346 0.000
L30.3 Infective dermatitis
0.654 0.346 0.000
L30.2 Cutaneous autosensitisation
0.654 0.346 0.000
L30.1 Dyshidrosis [pompholyx]
0.654 0.346 0.000
L30.0 Nummular dermatitis
0.654 0.346 0.000
S62 Fracture at wrist and hand level
0.654 0.346 0.000
I09 Other rheumatic heart diseases
0.653 0.347 0.000
I06 Rheumatic aortic valve diseases
0.653 0.347 0.000
E40-E46 Malnutrition
0.653 0.347 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.653 0.347 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.653 0.347 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.653 0.347 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.653 0.347 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.653 0.347 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.653 0.347 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.652 0.348 0.000
I50.1 Left ventricular failure
0.651 0.349 0.000
H60-H62 Diseases of external ear
0.651 0.349 0.000
H55-H59 Other disorders of eye and adnexa
0.651 0.349 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.651 0.349 0.000
H10-H13 Disorders of conjunctiva
0.651 0.349 0.000
L50-L54 Urticaria and erythema
0.650 0.349 0.000
K90-K93 Other diseases of the digestive system
0.650 0.350 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.650 0.350 0.000
N87.1 Moderate cervical dysplasia
0.650 0.350 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.650 0.350 0.000
S81 Open wound of lower leg
0.650 0.350 0.000
L57.0 Actinic keratosis
0.650 0.350 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.650 0.350 0.000
N89.7 Haematocolpos
0.650 0.350 0.000
N89.6 Tight hymenal ring
0.650 0.350 0.000
N89.5 Stricture and atresia of vagina
0.650 0.350 0.000
N89.4 Leukoplakia of vagina
0.650 0.350 0.000
N89.3 Dysplasia of vagina, unspecified
0.650 0.350 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.650 0.350 0.000
N89.1 Moderate vaginal dysplasia
0.650 0.350 0.000
N89.0 Mild vaginal dysplasia
0.650 0.350 0.000
O47 False labour
0.650 0.350 0.000
D62 Acute posthaemorrhagic anaemia
0.649 0.351 0.000
H34.2 Other retinal artery occlusions
0.649 0.351 0.000
I95 Hypotension
0.648 0.352 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.648 0.352 0.000
I50.0 Congestive heart failure
0.647 0.353 0.000
T87 Complications peculiar to reattachment and amputation
0.647 0.353 0.000
T86 Failure and rejection of transplanted organs and tissues
0.647 0.353 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.647 0.353 0.000
C15-C26 Malignant neoplasms of digestive organs
0.646 0.354 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.645 0.355 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.645 0.355 0.000
N84.2 Polyp of vagina
0.643 0.357 0.000
O72.3 Postpartum coagulation defects
0.642 0.358 0.000
O72.0 Third-stage haemorrhage
0.642 0.358 0.000
S89 Other and unspecified injuries of lower leg
0.642 0.358 0.000
L43 Lichen planus
0.642 0.358 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.641 0.359 0.000
H74 Other disorders of middle ear and mastoid
0.641 0.359 0.000
H70 Mastoiditis and related conditions
0.641 0.359 0.000
H69 Other disorders of Eustachian tube
0.641 0.359 0.000
H68 Eustachian salpingitis and obstruction
0.641 0.359 0.000
H67 Otitis media in diseases classified elsewhere
0.641 0.359 0.000
Z41 Procedures for purposes other than remedying health state
0.641 0.359 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.641 0.359 0.000
H80-H83 Diseases of inner ear
0.640 0.360 0.000
N90.7 Vulvar cyst
0.639 0.361 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.639 0.361 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.639 0.361 0.000
D47.1 Chronic myeloproliferative disease
0.638 0.361 0.000
C34.8 Overlapping lesion of bronchus and lung
0.638 0.362 0.000
C34.2 Middle lobe, bronchus or lung
0.638 0.362 0.000
C34.0 Main bronchus
0.638 0.362 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.638 0.362 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.638 0.362 0.000
Z39.1 Care and examination of lactating mother
0.637 0.362 0.000
K59 Other functional intestinal disorders
0.638 0.362 0.000
Z49.0 Preparatory care for dialysis
0.637 0.363 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.637 0.363 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.637 0.363 0.000
L03.3 Cellulitis of trunk
0.636 0.363 0.000
D46 Myelodysplastic syndromes
0.636 0.364 0.000
O03 Spontaneous abortion
0.636 0.364 0.000
Z38 Liveborn infants according to place of birth
0.635 0.365 0.000
Z32 Pregnancy examination and test
0.635 0.365 0.000
Z31 Procreative management
0.635 0.365 0.000
L44 Other papulosquamous disorders
0.633 0.366 0.000
L41 Parapsoriasis
0.633 0.366 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.633 0.366 0.000
L42 Pityriasis rosea
0.633 0.366 0.000
N35 Urethral stricture
0.634 0.366 0.000
Z28 Immunisation not carried out
0.633 0.367 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.633 0.367 0.000
Z26 Need for immunisation against other single infectious diseases
0.633 0.367 0.000
Z25 Need for immunisation against other single viral diseases
0.633 0.367 0.000
Z24 Need for immunisation against certain single viral diseases
0.633 0.367 0.000
Z23 Need for immunisation against single bacterial diseases
0.633 0.367 0.000
Z20 Contact with and exposure to communicable diseases
0.633 0.367 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.633 0.367 0.000
Z29.2 Other prophylactic chemotherapy
0.633 0.367 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.632 0.368 0.000
S69 Other and unspecified injuries of wrist and hand
0.632 0.368 0.000
S68 Traumatic amputation of wrist and hand
0.632 0.368 0.000
S67 Crushing injury of wrist and hand
0.632 0.368 0.000
S65 Injury of blood vessels at wrist and hand level
0.632 0.368 0.000
S60 Superficial injury of wrist and hand
0.632 0.368 0.000
C61 Malignant neoplasm of prostate
0.632 0.368 0.000
I69 Sequelae of cerebrovascular disease
0.632 0.368 0.000
D68.6 Other Thrombophilia
0.632 0.368 0.000
D68.5 Primary Thrombophilia
0.632 0.368 0.000
D68.4 Acquired coagulation factor deficiency
0.632 0.368 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.632 0.368 0.000
D68.1 Hereditary factor XI deficiency
0.632 0.368 0.000
D68.0 Von Willebrand's disease
0.632 0.368 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.630 0.369 0.000
N27 Small kidney of unknown cause
0.630 0.369 0.000
N25 Disorders resulting from impaired renal tubular function
0.630 0.369 0.000
N26 Unspecified contracted kidney
0.630 0.369 0.000
A30-A49 Other bacterial diseases
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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