TreeWAS – Variant ID: rs219976

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
Chapter I Certain infectious and parasitic diseases	0.999	0.001
Chapter XIV Diseases of the genitourinary system	0.998	0.002
A30-A49 Other bacterial diseases	0.997	0.003
O60-O75 Complications of labour and delivery	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
Chapter II Neoplasms	0.996	0.004
N17-N19 Renal failure	0.995	0.005
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006
N00-N08 Glomerular diseases	0.992	0.008
N18 Chronic renal failure	0.991	0.009
A41 Other septicaemia	0.989	0.011
M05-M14 Inflammatory polyarthropathies	0.986	0.014
N18.9 Chronic renal failure, unspecified	0.981	0.019
N03 Chronic nephritic syndrome	0.980	0.020
M06 Other rheumatoid arthritis	0.975	0.025
O70 Perineal laceration during delivery	0.973	0.027
N03.9 Unspecified	0.972	0.028
O70.1 Second degree perineal laceration during delivery	0.969	0.031
M80-M85 Disorders of bone density and structure	0.964	0.036
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.963	0.037
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.959	0.041
C43-C44 Melanoma and other malignant neoplasms of skin	0.959	0.041
M06.9 Rheumatoid arthritis, unspecified	0.956	0.044
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.955	0.045
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.950	0.050
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.950	0.050
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.947	0.053
Chapter IX Diseases of the circulatory system	0.945	0.055
C44 Other malignant neoplasms of skin	0.943	0.057
O69 Labour and delivery complicated by umbilical cord complications	0.937	0.063
Chapter XX External causes of morbidity and mortality	0.935	0.065
C34 Malignant neoplasm of bronchus and lung	0.932	0.068
O75 Other complications of labour and delivery, not elsewhere classified	0.930	0.070
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.930	0.070
C44.4 Skin of scalp and neck	0.928	0.072
C44.1 Skin of eyelid, including canthus	0.927	0.073
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.927	0.073
N25-N29 Other disorders of kidney and ureter	0.925	0.075
A41.0 Septicaemia due to Staphylococcus aureus	0.924	0.076
N10-N16 Renal tubulo-interstitial diseases	0.922	0.078
C34.9 Bronchus or lung, unspecified	0.920	0.080
I05-I09 Chronic rheumatic heart diseases	0.919	0.081
T20-T25 Burns and corrosions of external body surface, specified by site	0.916	0.084
A49 Bacterial infection of unspecified site	0.911	0.089
D60-D64 Aplastic and other anaemias	0.907	0.093
B35-B49 Mycoses	0.906	0.094
C90 Multiple myeloma and malignant plasma cell neoplasms	0.903	0.097
N08 Glomerular disorders in diseases classified elsewhere	0.903	0.097
A40 Streptococcal septicaemia	0.902	0.098
S32 Fracture of lumbar spine and pelvis	0.900	0.100
T36-T50 Poisoning by drugs, medicaments and biological substances	0.900	0.100
A41.5 Septicaemia due to other Gram-negative organisms	0.897	0.103
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.894	0.106
A41.9 Septicaemia, unspecified	0.893	0.107
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.893	0.107
N28 Other disorders of kidney and ureter, not elsewhere classified	0.884	0.116
C73 Malignant neoplasm of thyroid gland	0.882	0.118
N18.4 Chronic kidney disease, stage 4	0.881	0.119
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.876	0.124
S20-S29 Injuries to the thorax	0.874	0.126
C90.0 Multiple myeloma	0.870	0.130
N13 Obstructive and reflux uropathy	0.869	0.131
M80 Osteoporosis with pathological fracture	0.865	0.135
Chapter IV Endocrine, nutritional and metabolic diseases	0.865	0.135
I08 Multiple valve diseases	0.865	0.135
D37-D48 Neoplasms of uncertain or unknown behaviour	0.861	0.139
C51-C58 Malignant neoplasms of female genital organs	0.861	0.139
M84 Disorders of continuity of bone	0.859	0.141
S10-S19 Injuries to the neck	0.858	0.142
Y43 Primarily systemic agents	0.857	0.143
N18.0 End-stage renal disease	0.853	0.147
D64 Other anaemias	0.851	0.149
Chapter XII Diseases of the skin and subcutaneous tissue	0.850	0.150
N13.5 Kinking and stricture of ureter without hydronephrosis	0.849	0.151
T91 Sequelae of injuries of neck and trunk	0.845	0.155
N19 Unspecified renal failure	0.845	0.155
M06.0 Seronegative rheumatoid arthritis	0.845	0.155
B15-B19 Viral hepatitis	0.844	0.156
Y43.3 Other antineoplastic drugs	0.840	0.160
O32 Maternal care for known or suspected malpresentation of foetus	0.839	0.161
T93 Sequelae of injuries of lower limb	0.838	0.162
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.837	0.163
S32.0 Fracture of lumbar vertebra	0.836	0.164
M40-M43 Deforming dorsopathies	0.834	0.166
L80-L99 Other disorders of the skin and subcutaneous tissue	0.830	0.170
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.830	0.170
I10-I15 Hypertensive diseases	0.828	0.172
I27 Other pulmonary heart diseases	0.827	0.173
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.826	0.174
Y40 Systemic antibiotics	0.825	0.175
B37 Candidiasis	0.825	0.175
L90 Atrophic disorders of skin	0.825	0.175
L90.5 Scar conditions and fibrosis of skin	0.824	0.176
M91-M94 Chondropathies	0.822	0.178
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.814	0.185
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.814	0.186
T15-T19 Effects of foreign body entering through natural orifice	0.812	0.188
N28.9 Disorder of kidney and ureter, unspecified	0.812	0.188
N08.3 Glomerular disorders in diabetes mellitus	0.811	0.189
D64.9 Anaemia, unspecified	0.810	0.190
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.810	0.190
N18.5 Chronic kidney disease, stage 5	0.809	0.191
M80.9 Unspecified osteoporosis with pathological fracture	0.808	0.192
O69.1 Labour and delivery complicated by cord around neck, with compression	0.806	0.194
T46 Poisoning by agents primarily affecting the cardiovascular system	0.804	0.196
O46 Antepartum haemorrhage, not elsewhere classified	0.803	0.196
C91 Lymphoid leukaemia	0.803	0.197
T91.2 Sequelae of other fracture of thorax and pelvis	0.801	0.199
D62 Acute posthaemorrhagic anaemia	0.801	0.199
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.801	0.199
L91 Hypertrophic disorders of skin	0.800	0.200
O64 Obstructed labour due to malposition and malpresentation of foetus	0.799	0.201
B20-B24 Human immunodeficiency virus [HIV] disease	0.798	0.202
I07 Rheumatic tricuspid valve diseases	0.798	0.202
C44.0 Skin of lip	0.798	0.202
M13 Other arthritis	0.797	0.203
O69.8 Labour and delivery complicated by other cord complications	0.797	0.203
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.796	0.204
O75.7 Vaginal delivery following previous Caesarean section	0.796	0.204
E50-E64 Other nutritional deficiencies	0.796	0.204
C54 Malignant neoplasm of corpus uteri	0.795	0.205
D70-D77 Other diseases of blood and blood-forming organs	0.792	0.208
B25-B34 Other viral diseases	0.791	0.209
S32.00 Fracture of lumbar vertebra (closed)	0.791	0.209
A41.2 Septicaemia due to unspecified staphylococcus	0.786	0.214
O44 Placenta praevia	0.786	0.214
A49.8 Other bacterial infections of unspecified site	0.785	0.214
I30-I52 Other forms of heart disease	0.785	0.215
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.784	0.216
O48 Prolonged pregnancy	0.783	0.217
L91.8 Other hypertrophic disorders of skin	0.782	0.218
M86-M90 Other osteopathies	0.781	0.219
O35 Maternal care for known or suspected foetal abnormality and damage	0.779	0.220
M85 Other disorders of bone density and structure	0.777	0.223
O69.0 Labour and delivery complicated by prolapse of cord	0.776	0.224
N10 Acute tubulo-interstitial nephritis	0.776	0.224
O71 Other obstetric trauma	0.775	0.225
M14 Arthropathies in other diseases classified elsewhere	0.774	0.226
E20-E35 Disorders of other endocrine glands	0.772	0.228
I34 Nonrheumatic mitral valve disorders	0.772	0.228
M60-M63 Disorders of muscles	0.771	0.229
S36 Injury of intra-abdominal organs	0.771	0.229
O75.2 Pyrexia during labour, not elsewhere classified	0.770	0.230
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.770	0.230
E10-E14 Diabetes mellitus	0.769	0.231
O47 False labour	0.768	0.232
S31 Open wound of abdomen, lower back and pelvis	0.767	0.233
N18.8 Other chronic renal failure	0.766	0.234
I08.0 Disorders of both mitral and aortic valves	0.765	0.235
A15-A19 Tuberculosis	0.764	0.236
O43 Placental disorders	0.761	0.239
O62 Abnormalities of forces of labour	0.760	0.240
O75.0 Maternal distress during labour and delivery	0.760	0.240
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.757	0.243
O69.9 Labour and delivery complicated by cord complication, unspecified	0.755	0.245
W20-W49 Exposure to inanimate mechanical forces	0.755	0.245
A40.1 Septicaemia due to streptococcus, group B	0.755	0.245
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.754	0.246
A49.0 Staphylococcal infection, unspecified	0.753	0.247
E11 Non-insulin-dependent diabetes mellitus	0.752	0.248
T92 Sequelae of injuries of upper limb	0.751	0.249
M45-M49 Spondylopathies	0.750	0.250
I34.0 Mitral (valve) insufficiency	0.750	0.250
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.749	0.251
N17 Acute renal failure	0.748	0.252
C54.1 Endometrium	0.747	0.253
E53 Deficiency of other B group vitamins	0.746	0.254
M07 Psoriatic and enteropathic arthropathies	0.746	0.254
O40 Polyhydramnios	0.746	0.254
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.745	0.255
I27.0 Primary pulmonary hypertension	0.744	0.256
S32.5 Fracture of pubis	0.742	0.258
I15 Secondary hypertension	0.742	0.258
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.741	0.259
M06.4 Inflammatory polyarthropathy	0.740	0.260
M84.0 Malunion of fracture	0.740	0.260
O73 Retained placenta and membranes, without haemorrhage	0.740	0.260
B44 Aspergillosis	0.739	0.261
O75.8 Other specified complications of labour and delivery	0.739	0.261
C88 Malignant immunoproliferative diseases	0.738	0.261
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.737	0.262
M84.4 Pathological fracture, not elsewhere classified	0.737	0.263
I27.2 Other secondary pulmonary hypertension	0.736	0.264
M81 Osteoporosis without pathological fracture	0.736	0.264
S12 Fracture of neck	0.736	0.264
T21 Burn and corrosion of trunk	0.736	0.264
T93.2 Sequelae of other fractures of lower limb	0.733	0.267
A49.9 Bacterial infection, unspecified	0.732	0.268
N28.8 Other specified disorders of kidney and ureter	0.732	0.268
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.732	0.268
D80-D89 Certain disorders involving the immune mechanism	0.731	0.269
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.731	0.269
B37.8 Candidiasis of other sites	0.730	0.270
N13.9 Obstructive and reflux uropathy, unspecified	0.728	0.271
A40.8 Other streptococcal septicaemia	0.728	0.272
C49 Malignant neoplasm of other connective and soft tissue	0.727	0.272
T66-T78 Other and unspecified effects of external causes	0.726	0.274
S22 Fracture of rib(s), sternum and thoracic spine	0.726	0.274
N04 Nephrotic syndrome	0.726	0.274
N28.1 Cyst of kidney, acquired	0.726	0.274
S40-S49 Injuries to the shoulder and upper arm	0.725	0.275
N08.5 Glomerular disorders in systemic connective tissue disorders	0.724	0.276
B37.1 Pulmonary candidiasis	0.723	0.277
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.723	0.277
O16 Unspecified maternal hypertension	0.722	0.278
D45 Polycythaemia vera	0.721	0.279
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.721	0.279
C44.5 Skin of trunk	0.720	0.280
T20 Burn and corrosion of head and neck	0.720	0.280
Y60-Y69 Misadventures to patients during surgical and medical care	0.720	0.280
A80-A89 Viral infections of the central nervous system	0.719	0.281
I05 Rheumatic mitral valve diseases	0.719	0.281
M00-M03 Infectious arthropathies	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E27 Other disorders of adrenal gland	0.717	0.283
O66 Other obstructed labour	0.716	0.283
B99-B99 Other infectious diseases	0.716	0.284
B85-B89 Pediculosis, acariasis and other infestations	0.716	0.284
B65-B83 Helminthiases	0.716	0.284
B50-B64 Protozoal diseases	0.716	0.284
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284
A75-A79 Rickettsioses	0.716	0.284
A70-A74 Other diseases caused by chlamydiae	0.716	0.284
A65-A69 Other spirochaetal diseases	0.716	0.284
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284
X50-X57 Overexertion, travel and privation	0.716	0.284
A48 Other bacterial diseases, not elsewhere classified	0.715	0.285
A44 Bartonellosis	0.715	0.285
A43 Nocardiosis	0.715	0.285
A42 Actinomycosis	0.715	0.285
A39 Meningococcal infection	0.715	0.285
A37 Whooping cough	0.715	0.285
A36 Diphtheria	0.715	0.285
A32 Listeriosis	0.715	0.285
A31 Infection due to other mycobacteria	0.715	0.285
A30 Leprosy [Hansen's disease]	0.715	0.285
A38 Scarlet fever	0.715	0.285
A35 Other tetanus	0.715	0.285
A34 Obstetrical tetanus	0.715	0.285
A33 Tetanus neonatorum	0.715	0.285
O74 Complications of anaesthesia during labour and delivery	0.715	0.285
O65 Obstructed labour due to maternal pelvic abnormality	0.715	0.285
O61 Failed induction of labour	0.715	0.285
O60 Preterm delivery	0.715	0.285
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.286
I12 Hypertensive renal disease	0.714	0.286
S30 Superficial injury of abdomen, lower back and pelvis	0.714	0.286
O30 Multiple gestation	0.714	0.286
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.714	0.286
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
A40.3 Septicaemia due to Streptococcus pneumoniae	0.712	0.287
M11 Other crystal arthropathies	0.711	0.289
N07 Hereditary nephropathy, not elsewhere classified	0.711	0.289
N06 Isolated proteinuria with specified morphological lesion	0.711	0.289
N01 Rapidly progressive nephritic syndrome	0.711	0.289
N00 Acute nephritic syndrome	0.711	0.289
I07.1 Tricuspid insufficiency	0.711	0.289
N18.1 Chronic kidney disease, stage 1	0.711	0.289
E53.8 Deficiency of other specified B group vitamins	0.711	0.289
A41.4 Septicaemia due to anaerobes	0.709	0.291
A41.3 Septicaemia due to Haemophilus influenzae	0.709	0.291
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.708	0.292
M12 Other specific arthropathies	0.707	0.293
M09 Juvenile arthritis in diseases classified elsewhere	0.707	0.293
M08 Juvenile arthritis	0.707	0.293
X40-X49 Accidental poisoning by and exposure to noxious substances	0.706	0.294
N02 Recurrent and persistent haematuria	0.706	0.294
E11.5 With peripheral circulatory complications	0.705	0.295
C15-C26 Malignant neoplasms of digestive organs	0.705	0.295
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.704	0.296
O85-O92 Complications predominantly related to the puerperium	0.704	0.296
I35 Nonrheumatic aortic valve disorders	0.704	0.296
N03.8 Other	0.703	0.297
N03.7 Diffuse crescentic glomerulonephritis	0.703	0.297
N03.6 Dense deposit disease	0.703	0.297
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.703	0.297
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.703	0.297
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.703	0.297
N03.2 Diffuse membranous glomerulonephritis	0.703	0.297
N03.1 Focal and segmental glomerular lesions	0.703	0.297
N03.0 Minor glomerular abnormality	0.703	0.297
Y48 Anaesthetics and therapeutic gases	0.702	0.298
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.701	0.299
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.701	0.299
M06.3 Rheumatoid nodule	0.700	0.300
T40.2 Other opioids	0.700	0.300
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.700	0.300
C71 Malignant neoplasm of brain	0.700	0.300
M43 Other deforming dorsopathies	0.700	0.300
T94 Sequelae of injuries involving multiple and unspecified body regions	0.700	0.300
M06.8 Other specified rheumatoid arthritis	0.699	0.301
M06.2 Rheumatoid bursitis	0.699	0.301
M06.1 Adult-onset Still's disease	0.699	0.301
O32.8 Maternal care for other malpresentation of foetus	0.699	0.301
O70.9 Perineal laceration during delivery, unspecified	0.698	0.302
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.698	0.302
O70.3 Fourth degree perineal laceration during delivery	0.698	0.302
A50-A64 Infections with a predominantly sexual mode of transmission	0.698	0.302
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.697	0.303
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.696	0.304
I11 Hypertensive heart disease	0.695	0.305
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.694	0.305
N13.8 Other obstructive and reflux uropathy	0.694	0.306
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.693	0.307
M83 Adult osteomalacia	0.691	0.309
O45 Premature separation of placenta [abruptio placentae]	0.690	0.309
O33 Maternal care for known or suspected disproportion	0.690	0.309
O31 Complications specific to multiple gestation	0.690	0.309
T23 Burn and corrosion of wrist and hand	0.690	0.310
Y40.3 Macrolides	0.690	0.310
O46.9 Antepartum haemorrhage, unspecified	0.689	0.311
T98 Sequelae of other and unspecified effects of external causes	0.689	0.311
X10-X19 Contact with heat and hot substances	0.688	0.312
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.688	0.312
S37 Injury of urinary and pelvic organs	0.688	0.312
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.688	0.312
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.688	0.312
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.688	0.312
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.688	0.312
V80-V89 Other land transport accidents	0.687	0.312
C57 Malignant neoplasm of other and unspecified female genital organs	0.687	0.313
A46 Erysipelas	0.687	0.313
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.686	0.314
M06.98 Rheumatoid arthritis, unspecified (Other)	0.685	0.314
N18.2 Chronic kidney disease, stage 2	0.685	0.315
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.685	0.315
C38 Malignant neoplasm of heart, mediastinum and pleura	0.685	0.315
C31 Malignant neoplasm of accessory sinuses	0.685	0.315
C30 Malignant neoplasm of nasal cavity and middle ear	0.685	0.315
C37 Malignant neoplasm of thymus	0.685	0.315
C33 Malignant neoplasm of trachea	0.685	0.315
A41.8 Other specified septicaemia	0.683	0.317
B18 Chronic viral hepatitis	0.682	0.318
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.682	0.318
T95 Sequelae of burns, corrosions and frostbite	0.681	0.319
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.681	0.319
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.681	0.319
I15.1 Hypertension secondary to other renal disorders	0.680	0.320
X58-X59 Accidental exposure to other and unspecified factors	0.679	0.321
O44.1 Placenta praevia with haemorrhage	0.679	0.321
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.679	0.321
C95 Leukaemia of unspecified cell type	0.679	0.321
C94 Other leukaemias of specified cell type	0.679	0.321
C93 Monocytic leukaemia	0.679	0.321
C86 Other specified types of T/NK-cell lymphoma	0.679	0.321
C84 Peripheral and cutaneous T-cell lymphomas	0.679	0.321
A41.1 Septicaemia due to other specified staphylococcus	0.679	0.321
C83 Diffuse non-Hodgkin's lymphoma	0.679	0.321
E11.3 With ophthalmic complications	0.679	0.321
M50-M54 Other dorsopathies	0.678	0.322
I00-I02 Acute rheumatic fever	0.678	0.322
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.677	0.323
C44.8 Overlapping lesion of skin	0.676	0.323
C34.0 Main bronchus	0.675	0.324
T46.4 Angiotensin-converting-enzyme inhibitors	0.675	0.325
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.675	0.325
S27 Injury of other and unspecified intrathoracic organs	0.675	0.325
E11.2 With renal complications	0.675	0.325
T40.4 Other synthetic narcotics	0.674	0.325
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.674	0.326
B49 Unspecified mycosis	0.673	0.327
Y40.0 Penicillins	0.673	0.327
I36 Nonrheumatic tricuspid valve disorders	0.672	0.328
M82 Osteoporosis in diseases classified elsewhere	0.672	0.328
I60-I69 Cerebrovascular diseases	0.672	0.328
O69.5 Labour and delivery complicated by vascular lesion of cord	0.672	0.328
O69.4 Labour and delivery complicated by vasa praevia	0.672	0.328
O69.3 Labour and delivery complicated by short cord	0.672	0.328
V40-V49 Car occupant injured in transport accident	0.671	0.328
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.671	0.329
Y35-Y36 Legal intervention and operations of war	0.671	0.329
Y10-Y34 Event of undetermined intent	0.671	0.329
Y00-Y09 Assault	0.671	0.329
X85-X99 Assault	0.671	0.329
X30-X39 Exposure to forces of nature	0.671	0.329
X00-X09 Exposure to smoke, fire and flames	0.671	0.329
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.671	0.329
W75-W84 Other accidental threats to breathing	0.671	0.329
W65-W74 Accidental drowning and submersion	0.671	0.329
V98-V99 Other and unspecified transport accidents	0.671	0.329
V95-V97 Air and space transport accidents	0.671	0.329
V90-V94 Water transport accidents	0.671	0.329
V70-V79 Bus occupant injured in transport accident	0.671	0.329
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.671	0.329
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.671	0.329
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.671	0.329
V01-V09 Pedestrian injured in transport accident	0.671	0.329
A40.9 Streptococcal septicaemia, unspecified	0.668	0.332
C34.8 Overlapping lesion of bronchus and lung	0.668	0.332
S32.3 Fracture of ilium	0.667	0.333
O75.9 Complication of labour and delivery, unspecified	0.667	0.333
O75.5 Delayed delivery after artificial rupture of membranes	0.667	0.333
O75.4 Other complications of obstetric surgery and procedures	0.667	0.333
O75.3 Other infection during labour	0.667	0.333
O75.1 Shock during or following labour and delivery	0.667	0.333
O32.0 Maternal care for unstable lie	0.667	0.333
C75 Malignant neoplasm of other endocrine glands and related structures	0.666	0.333
C74 Malignant neoplasm of adrenal gland	0.666	0.333
N05 Unspecified nephritic syndrome	0.666	0.334
C51 Malignant neoplasm of vulva	0.666	0.334
S90-S99 Injuries to the ankle and foot	0.666	0.334
C34.3 Lower lobe, bronchus or lung	0.666	0.334
C44.9 Malignant neoplasm of skin, unspecified	0.665	0.335
M94 Other disorders of cartilage	0.665	0.335
T93.1 Sequelae of fracture of femur	0.664	0.336
T79-T79 Certain early complications of trauma	0.664	0.336
Y40.8 Other systemic antibiotics	0.664	0.336
S20 Superficial injury of thorax	0.664	0.336
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.664	0.336
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.663	0.336
N27 Small kidney of unknown cause	0.663	0.336
N25 Disorders resulting from impaired renal tubular function	0.663	0.336
S29 Other and unspecified injuries of thorax	0.663	0.337
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.663	0.337
L60-L75 Disorders of skin appendages	0.662	0.338
Y85 Sequelae of transport accidents	0.661	0.339
O32.2 Maternal care for transverse and oblique lie	0.661	0.339
C91.0 Acute lymphoblastic leukaemia	0.661	0.339
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.661	0.339
N15 Other renal tubulo-interstitial diseases	0.661	0.339
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.661	0.339
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.661	0.339
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.660	0.340
B37.0 Candidal stomatitis	0.659	0.341
I09 Other rheumatic heart diseases	0.659	0.341
I06 Rheumatic aortic valve diseases	0.659	0.341
C92 Myeloid leukaemia	0.658	0.342
B17 Other acute viral hepatitis	0.658	0.342
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.657	0.343
T25 Burn and corrosion of ankle and foot	0.657	0.343
O63 Long labour	0.657	0.343
C90.2 Plasmacytoma, extramedullary	0.656	0.344
M70-M79 Other soft tissue disorders	0.656	0.344
T90 Sequelae of injuries of head	0.656	0.344
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.656	0.344
T50.9 Other and unspecified drugs, medicaments and biological substances	0.655	0.345
O41 Other disorders of amniotic fluid and membranes	0.654	0.346
B24 Unspecified human immunodeficiency virus [HIV] disease	0.654	0.346
M10 Gout	0.654	0.346
T17 Foreign body in respiratory tract	0.653	0.347
A49.3 Mycoplasma infection, unspecified	0.653	0.347
A49.2 Haemophilus influenzae infection, unspecified	0.653	0.347
I27.8 Other specified pulmonary heart diseases	0.653	0.347
M65-M68 Disorders of synovium and tendon	0.652	0.348
T46.1 Calcium-channel blockers	0.652	0.348
O72 Postpartum haemorrhage	0.651	0.349
E27.4 Other and unspecified adrenocortical insufficiency	0.651	0.349
X60-X84 Intentional self-harm	0.651	0.349
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.650	0.350
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.650	0.350
B48 Other mycoses, not elsewhere classified	0.649	0.351
B47 Mycetoma	0.649	0.351
B46 Zygomycosis	0.649	0.351
B45 Cryptococcosis	0.649	0.351
B43 Chromomycosis and phaeomycotic abscess	0.649	0.351
B42 Sporotrichosis	0.649	0.351
B41 Paracoccidioidomycosis	0.649	0.351
B40 Blastomycosis	0.649	0.351
B39 Histoplasmosis	0.649	0.351
B38 Coccidioidomycosis	0.649	0.351
B36 Other superficial mycoses	0.649	0.351
O47.1 False labour at or after 37 completed weeks of gestation	0.649	0.351
T93.8 Sequelae of other specified injuries of lower limb	0.649	0.351
M84.48 Pathological fracture, not elsewhere classified (Other)	0.649	0.351
M13.9 Arthritis, unspecified	0.648	0.352
S32.4 Fracture of acetabulum	0.647	0.352
C90.3 Solitary plasmacytoma	0.647	0.353
C90.1 Plasma cell leukaemia	0.647	0.353
N08.8 Glomerular disorders in other diseases classified elsewhere	0.647	0.353
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.647	0.353
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.647	0.353
N08.1 Glomerular disorders in neoplastic diseases	0.647	0.353
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.647	0.353
W50-W64 Exposure to animate mechanical forces	0.647	0.353
Y40.1 Cefalosporins and other -lactam antibiotics	0.647	0.353
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.647	0.353
A40.2 Septicaemia due to streptococcus, group D	0.647	0.353
A40.0 Septicaemia due to streptococcus, group A	0.647	0.353
D75 Other diseases of blood and blood-forming organs	0.647	0.353
I34.1 Mitral (valve) prolapse	0.647	0.353
I35.1 Aortic (valve) insufficiency	0.646	0.354
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.645	0.354
S32.2 Fracture of coccyx	0.645	0.354
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.645	0.355
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.645	0.355
T41 Poisoning by anaesthetics and therapeutic gases	0.645	0.355
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.645	0.355
T36 Poisoning by systemic antibiotics	0.645	0.355
M85.6 Other cyst of bone	0.645	0.355
I12.0 Hypertensive renal disease with renal failure	0.645	0.355
X20-X29 Contact with venomous animals and plants	0.643	0.356
S19 Other and unspecified injuries of neck	0.643	0.357
N13.6 Pyonephrosis	0.642	0.358
I46 Cardiac arrest	0.642	0.358
O15 Eclampsia	0.641	0.359
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.641	0.359

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations