TreeWAS – Variant ID: rs75779669

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter X Diseases of the respiratory system	0.999	0.001
K50-K52 Noninfective enteritis and colitis	0.998	0.002
M70-M79 Other soft tissue disorders	0.997	0.003
Chapter IX Diseases of the circulatory system	0.996	0.004
K51 Ulcerative colitis	0.995	0.005
M75 Shoulder lesions	0.995	0.005
J40-J47 Chronic lower respiratory diseases	0.994	0.006
J45 Asthma	0.993	0.007
J45.9 Asthma, unspecified	0.992	0.008
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.991	0.009
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.989	0.011
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.989	0.011
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.986	0.014
I26 Pulmonary embolism	0.984	0.016
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.980	0.020
K55-K64 Other diseases of intestines	0.979	0.021
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.979	0.021
Chapter IV Endocrine, nutritional and metabolic diseases	0.977	0.023
K51.9 Ulcerative colitis, unspecified	0.977	0.023
Chapter VIII Diseases of the ear and mastoid process	0.975	0.025
Z91 Personal history of risk-factors, not elsewhere classified	0.973	0.027
M20-M25 Other joint disorders	0.971	0.029
D10-D36 Benign neoplasms	0.968	0.032
T81 Complications of procedures, not elsewhere classified	0.967	0.033
K63 Other diseases of intestine	0.966	0.034
M75.4 Impingement syndrome of shoulder	0.965	0.035
Chapter XX External causes of morbidity and mortality	0.963	0.037
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.963	0.037
Chapter XIV Diseases of the genitourinary system	0.959	0.041
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.956	0.044
H90-H95 Other disorders of ear	0.956	0.044
Z86 Personal history of certain other diseases	0.953	0.047
I30-I52 Other forms of heart disease	0.948	0.052
Z00-Z13 Persons encountering health services for examination and investigation	0.948	0.052
M23 Internal derangement of knee	0.945	0.055
T81.4 Infection following a procedure, not elsewhere classified	0.944	0.056
Z83 Family history of other specific disorders	0.940	0.060
K62 Other diseases of anus and rectum	0.937	0.063
E00-E07 Disorders of thyroid gland	0.936	0.064
K65-K67 Diseases of peritoneum	0.926	0.074
N30-N39 Other diseases of urinary system	0.926	0.074
K62.8 Other specified diseases of anus and rectum	0.924	0.076
D25 Leiomyoma of uterus	0.922	0.078
H91 Other hearing loss	0.921	0.079
Z90 Acquired absence of organs, not elsewhere classified	0.920	0.080
E70-E90 Metabolic disorders	0.920	0.080
C15-C26 Malignant neoplasms of digestive organs	0.920	0.080
C78.7 Secondary malignant neoplasm of liver	0.919	0.081
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.919	0.081
K40-K46 Hernia	0.917	0.083
K50 Crohn's disease [regional enteritis]	0.915	0.085
K63.1 Perforation of intestine (nontraumatic)	0.915	0.085
Z85 Personal history of malignant neoplasm	0.913	0.087
I05-I09 Chronic rheumatic heart diseases	0.912	0.088
N32 Other disorders of bladder	0.911	0.089
Z93 Artificial opening status	0.909	0.091
Z85.4 Personal history of malignant neoplasm of genital organs	0.905	0.095
J95-J99 Other diseases of the respiratory system	0.901	0.099
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.900	0.100
Z80 Family history of malignant neoplasm	0.899	0.101
Z98 Other postsurgical states	0.898	0.102
H91.9 Hearing loss, unspecified	0.897	0.103
M75.1 Rotator cuff syndrome	0.896	0.104
J43 Emphysema	0.896	0.104
Z08 Follow-up examination after treatment for malignant neoplasm	0.895	0.105
D25.9 Leiomyoma of uterus, unspecified	0.895	0.105
D00-D09 In situ neoplasms	0.895	0.105
I49 Other cardiac arrhythmias	0.894	0.106
K51.3 Ulcerative (chronic) rectosigmoiditis	0.893	0.107
Z86.7 Personal history of diseases of the circulatory system	0.891	0.109
C78.0 Secondary malignant neoplasm of lung	0.890	0.110
M75.0 Adhesive capsulitis of shoulder	0.890	0.110
I47 Paroxysmal tachycardia	0.888	0.112
T84.0 Mechanical complication of internal joint prosthesis	0.888	0.112
N32.0 Bladder-neck obstruction	0.887	0.113
C43-C44 Melanoma and other malignant neoplasms of skin	0.887	0.113
C18 Malignant neoplasm of colon	0.885	0.115
E03 Other hypothyroidism	0.881	0.119
E05 Thyrotoxicosis [hyperthyroidism]	0.877	0.123
Z97 Presence of other devices	0.871	0.129
I47.2 Ventricular tachycardia	0.869	0.131
M23.2 Derangement of meniscus due to old tear or injury	0.868	0.132
M65-M68 Disorders of synovium and tendon	0.868	0.132
N10-N16 Renal tubulo-interstitial diseases	0.866	0.134
Chapter I Certain infectious and parasitic diseases	0.858	0.142
J30-J39 Other diseases of upper respiratory tract	0.856	0.144
T81.3 Disruption of operation wound, not elsewhere classified	0.856	0.144
E86 Volume depletion	0.855	0.145
M75.3 Calcific tendinitis of shoulder	0.854	0.146
Z70-Z76 Persons encountering health services in other circumstances	0.854	0.146
K65 Peritonitis	0.852	0.148
N32.8 Other specified disorders of bladder	0.851	0.149
K43 Ventral hernia	0.849	0.151
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.848	0.152
I08 Multiple valve diseases	0.843	0.157
E03.9 Hypothyroidism, unspecified	0.842	0.158
C60-C63 Malignant neoplasms of male genital organs	0.841	0.159
N70-N77 Inflammatory diseases of female pelvic organs	0.841	0.159
Z98.0 Intestinal bypass and anastomosis status	0.841	0.159
K51.2 Ulcerative (chronic) proctitis	0.836	0.164
E87 Other disorders of fluid, electrolyte and acid-base balance	0.835	0.165
D37-D48 Neoplasms of uncertain or unknown behaviour	0.835	0.165
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.835	0.165
C44 Other malignant neoplasms of skin	0.834	0.166
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.833	0.167
M23.3 Other meniscus derangements	0.832	0.168
D27 Benign neoplasm of ovary	0.832	0.168
M80-M85 Disorders of bone density and structure	0.828	0.172
Z80.0 Family history of malignant neoplasm of digestive organs	0.828	0.172
J43.9 Emphysema, unspecified	0.826	0.174
C44.3 Skin of other and unspecified parts of face	0.823	0.177
Z22 Carrier of infectious disease	0.823	0.177
Z83.5 Family history of eye and ear disorders	0.823	0.177
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.821	0.179
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.821	0.179
K63.8 Other specified diseases of intestine	0.821	0.179
J00-J06 Acute upper respiratory infections	0.819	0.181
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.819	0.181
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.818	0.182
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.816	0.183
Chapter XXII Codes for special purposes	0.816	0.184
K90-K93 Other diseases of the digestive system	0.816	0.184
Chapter VII Diseases of the eye and adnexa	0.814	0.186
Z11 Special screening examination for infectious and parasitic diseases	0.813	0.187
M50-M54 Other dorsopathies	0.812	0.188
I45 Other conduction disorders	0.811	0.189
H60-H62 Diseases of external ear	0.810	0.189
Z83.3 Family history of diabetes mellitus	0.810	0.190
N00-N08 Glomerular diseases	0.810	0.190
E20-E35 Disorders of other endocrine glands	0.810	0.190
M21 Other acquired deformities of limbs	0.810	0.190
K63.9 Disease of intestine, unspecified	0.809	0.191
C78.2 Secondary malignant neoplasm of pleura	0.808	0.192
E05.9 Thyrotoxicosis, unspecified	0.807	0.193
J98 Other respiratory disorders	0.807	0.193
Chapter VI Diseases of the nervous system	0.805	0.195
Z93.3 Colostomy status	0.803	0.197
N17-N19 Renal failure	0.803	0.197
K62.4 Stenosis of anus and rectum	0.801	0.199
I38 Endocarditis, valve unspecified	0.800	0.200
S50-S59 Injuries to the elbow and forearm	0.796	0.204
D35 Benign neoplasm of other and unspecified endocrine glands	0.793	0.207
Z86.0 Personal history of other neoplasms	0.793	0.207
K51.8 Other ulcerative colitis	0.792	0.208
A30-A49 Other bacterial diseases	0.791	0.209
Z90.4 Acquired absence of other parts of digestive tract	0.791	0.209
I08.1 Disorders of both mitral and tricuspid valves	0.789	0.211
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.787	0.213
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.786	0.214
K51.0 Ulcerative (chronic) enterocolitis	0.786	0.214
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.784	0.216
C19 Malignant neoplasm of rectosigmoid junction	0.783	0.217
Z13 Special screening examination for other diseases and disorders	0.782	0.218
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.782	0.218
M31 Other necrotising vasculopathies	0.780	0.220
K43.9 Ventral hernia without obstruction or gangrene	0.780	0.220
K63.3 Ulcer of intestine	0.779	0.221
Z03 Medical observation and evaluation for suspected diseases and conditions	0.779	0.221
H90 Conductive and sensorineural hearing loss	0.776	0.224
Z93.2 Ileostomy status	0.776	0.224
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.775	0.225
K62.9 Disease of anus and rectum, unspecified	0.772	0.228
Z90.7 Acquired absence of genital organ(s)	0.772	0.228
D34 Benign neoplasm of thyroid gland	0.771	0.229
Z90.1 Acquired absence of breast(s)	0.771	0.229
K50.1 Crohn's disease of large intestine	0.771	0.229
D04 Carcinoma in situ of skin	0.770	0.230
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.770	0.230
D33 Benign neoplasm of brain and other parts of central nervous system	0.769	0.231
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.769	0.231
I49.3 Ventricular premature depolarisation	0.768	0.232
K65.0 Acute peritonitis	0.768	0.232
Z22.3 Carrier of other specified bacterial diseases	0.767	0.233
J34 Other disorders of nose and nasal sinuses	0.766	0.234
C18.9 Colon, unspecified	0.765	0.235
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.765	0.235
M75.5 Bursitis of shoulder	0.764	0.236
K63.2 Fistula of intestine	0.763	0.237
K50.9 Crohn's disease, unspecified	0.762	0.238
I27 Other pulmonary heart diseases	0.761	0.239
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.761	0.239
D32 Benign neoplasm of meninges	0.760	0.240
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.758	0.242
Z97.5 Presence of (intra-uterine) contraceptive device	0.757	0.243
M24 Other specific joint derangements	0.756	0.243
M91-M94 Chondropathies	0.756	0.244
Z04 Examination and observation for other reasons	0.756	0.244
K42 Umbilical hernia	0.754	0.246
E87.6 Hypokalaemia	0.754	0.246
I49.9 Cardiac arrhythmia, unspecified	0.754	0.246
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.754	0.246
Z86.4 Personal history of psychoactive substance abuse	0.753	0.247
D25.0 Submucous leiomyoma of uterus	0.752	0.248
Z86.1 Personal history of infectious and parasitic diseases	0.750	0.249
K62.6 Ulcer of anus and rectum	0.750	0.250
Z90.2 Acquired absence of lung [part of]	0.749	0.251
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.749	0.251
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.748	0.252
W20-W49 Exposure to inanimate mechanical forces	0.748	0.252
T88 Other complications of surgical and medical care, not elsewhere classified	0.748	0.252
C18.0 Caecum	0.747	0.253
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.747	0.253
N19 Unspecified renal failure	0.747	0.253
J46 Status asthmaticus	0.746	0.254
M23.4 Loose body in knee	0.745	0.255
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.744	0.256
S80-S89 Injuries to the knee and lower leg	0.743	0.257
M23.8 Other internal derangements of knee	0.742	0.258
K66 Other disorders of peritoneum	0.742	0.258
Z83.7 Family history of diseases of the digestive system	0.740	0.260
K44 Diaphragmatic hernia	0.740	0.260
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.740	0.260
C79 Secondary malignant neoplasm of other sites	0.740	0.260
H92 Otalgia and effusion of ear	0.740	0.260
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.739	0.261
K50.0 Crohn's disease of small intestine	0.738	0.262
C62 Malignant neoplasm of testis	0.736	0.264
M77 Other enthesopathies	0.735	0.264
J60-J70 Lung diseases due to external agents	0.735	0.264
K62.3 Rectal prolapse	0.735	0.265
T85 Complications of other internal prosthetic devices, implants and grafts	0.735	0.265
I46 Cardiac arrest	0.734	0.266
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.734	0.266
W00-W19 Falls	0.734	0.266
M86-M90 Other osteopathies	0.734	0.266
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.733	0.266
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.733	0.267
T84.1 Mechanical complication of internal fixation device of bones of limb	0.732	0.268
T79-T79 Certain early complications of trauma	0.732	0.268
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.731	0.269
N36 Other disorders of urethra	0.731	0.269
M67 Other disorders of synovium and tendon	0.730	0.270
C18.5 Splenic flexure	0.730	0.270
E40-E46 Malnutrition	0.729	0.271
N35 Urethral stricture	0.729	0.271
M72 Fibroblastic disorders	0.728	0.271
N76 Other inflammation of vagina and vulva	0.728	0.271
M79 Other soft tissue disorders, not elsewhere classified	0.727	0.273
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.726	0.274
E05.0 Thyrotoxicosis with diffuse goitre	0.726	0.274
C18.7 Sigmoid colon	0.725	0.275
K41 Femoral hernia	0.724	0.276
D21 Other benign neoplasms of connective and other soft tissue	0.723	0.277
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.722	0.277
Chapter V Mental and behavioural disorders	0.723	0.277
Z80.4 Family history of malignant neoplasm of genital organs	0.722	0.278
Z72 Problems related to lifestyle	0.722	0.278
N34 Urethritis and urethral syndrome	0.721	0.279
N70 Salpingitis and oophoritis	0.719	0.281
I49.8 Other specified cardiac arrhythmias	0.719	0.281
I83 Varicose veins of lower extremities	0.719	0.281
I42 Cardiomyopathy	0.719	0.281
N02 Recurrent and persistent haematuria	0.719	0.281
D24 Benign neoplasm of breast	0.718	0.282
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z89 Acquired absence of limb	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
T66-T78 Other and unspecified effects of external causes	0.717	0.283
J90-J94 Other diseases of pleura	0.715	0.285
M76 Enthesopathies of lower limb, excluding foot	0.715	0.285
M73 Soft tissue disorders in diseases classified elsewhere	0.715	0.285
M71 Other bursopathies	0.715	0.285
M70 Soft tissue disorders related to use, overuse and pressure	0.715	0.285
D14 Benign neoplasm of middle ear and respiratory system	0.715	0.285
I00-I02 Acute rheumatic fever	0.714	0.286
K51.5 Mucosal proctocolitis	0.713	0.287
K51.4 Pseudopolyposis of colon	0.713	0.287
K51.1 Ulcerative (chronic) ileocolitis	0.713	0.287
M75.8 Other shoulder lesions	0.713	0.287
M75.9 Shoulder lesion, unspecified	0.713	0.287
M75.2 Bicipital tendinitis	0.713	0.287
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.713	0.287
D10 Benign neoplasm of mouth and pharynx	0.713	0.287
D09 Carcinoma in situ of other and unspecified sites	0.713	0.287
J41 Simple and mucopurulent chronic bronchitis	0.713	0.287
J42 Unspecified chronic bronchitis	0.713	0.287
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.712	0.288
J45.8 Mixed asthma	0.712	0.288
J45.1 Nonallergic asthma	0.712	0.288
T33-T35 Frostbite	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
T20-T25 Burns and corrosions of external body surface, specified by site	0.711	0.289
T00-T07 Injuries involving multiple body regions	0.711	0.289
S10-S19 Injuries to the neck	0.711	0.289
J95 Postprocedural respiratory disorders, not elsewhere classified	0.711	0.289
Z91.5 Personal history of self-harm	0.710	0.290
Y83.1 Surgical operation with implant of artificial internal device	0.710	0.290
I28 Other diseases of pulmonary vessels	0.709	0.291
Z13.9 Special screening examination, unspecified	0.709	0.291
T87 Complications peculiar to reattachment and amputation	0.709	0.291
T86 Failure and rejection of transplanted organs and tissues	0.709	0.291
T80 Complications following infusion, transfusion and therapeutic injection	0.709	0.291
Y84.8 Other medical procedures	0.709	0.291
I35 Nonrheumatic aortic valve disorders	0.708	0.292
D36 Benign neoplasm of other and unspecified sites	0.708	0.292
C76 Malignant neoplasm of other and ill-defined sites	0.707	0.293
Z86.6 Personal history of diseases of the nervous system and sense organs	0.707	0.293
S90-S99 Injuries to the ankle and foot	0.706	0.294
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.705	0.295
I49.0 Ventricular fibrillation and flutter	0.705	0.295
A41 Other septicaemia	0.705	0.295
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.704	0.296
Z03.4 Observation for suspected myocardial infarction	0.704	0.296
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.704	0.296
D05 Carcinoma in situ of breast	0.703	0.297
I45.1 Other and unspecified right bundle-branch block	0.703	0.297
K64 Haemorrhoids and perianal venous thrombosis	0.702	0.298
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.702	0.298
C78.4 Secondary malignant neoplasm of small intestine	0.702	0.298
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.702	0.298
C78.1 Secondary malignant neoplasm of mediastinum	0.702	0.298
K60 Fissure and fistula of anal and rectal regions	0.701	0.299
T15-T19 Effects of foreign body entering through natural orifice	0.701	0.299
J03 Acute tonsillitis	0.701	0.299
K56 Paralytic ileus and intestinal obstruction without hernia	0.700	0.300
Z97.8 Presence of other specified devices	0.699	0.301
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.698	0.301
K65.9 Peritonitis, unspecified	0.698	0.302
M65 Synovitis and tenosynovitis	0.698	0.302
S70-S79 Injuries to the hip and thigh	0.698	0.302
Z93.5 Cystostomy status	0.698	0.302
S60-S69 Injuries to the wrist and hand	0.697	0.303
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.697	0.303
Z91.7 Personal history of female genital mutilation	0.697	0.303
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.697	0.303
Z91.3 Personal history of unhealthy sleep-wake schedule	0.697	0.303
Z91.2 Personal history of poor personal hygiene	0.697	0.303
D18 Haemangioma and lymphangioma, any site	0.697	0.303
M35 Other systemic involvement of connective tissue	0.696	0.304
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.696	0.304
M34 Systemic sclerosis	0.696	0.304
M33 Dermatopolymyositis	0.696	0.304
M32 Systemic lupus erythematosus	0.696	0.304
M30 Polyarteritis nodosa and related conditions	0.696	0.304
E87.3 Alkalosis	0.696	0.304
E88 Other metabolic disorders	0.694	0.306
D31 Benign neoplasm of eye and adnexa	0.694	0.306
D30 Benign neoplasm of urinary organs	0.694	0.306
D29 Benign neoplasm of male genital organs	0.694	0.306
D28 Benign neoplasm of other and unspecified female genital organs	0.694	0.306
D26 Other benign neoplasms of uterus	0.694	0.306
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.694	0.306
D19 Benign neoplasm of mesothelial tissue	0.694	0.306
D16 Benign neoplasm of bone and articular cartilage	0.694	0.306
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.694	0.306
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.694	0.306
T81.9 Unspecified complication of procedure	0.693	0.306
T81.7 Vascular complications following a procedure, not elsewhere classified	0.693	0.306
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.693	0.306
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.693	0.306
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.693	0.306
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.693	0.307
C51-C58 Malignant neoplasms of female genital organs	0.693	0.307
K63.4 Enteroptosis	0.693	0.307
K63.0 Abscess of intestine	0.693	0.307
Z74 Problems related to care-provider dependency	0.693	0.307
D11 Benign neoplasm of major salivary glands	0.692	0.308
M23.30 Other meniscus derangements (Multiple sites)	0.692	0.308
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.691	0.308
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.691	0.309
Y35-Y36 Legal intervention and operations of war	0.691	0.309
Y10-Y34 Event of undetermined intent	0.691	0.309
Y00-Y09 Assault	0.691	0.309
X85-X99 Assault	0.691	0.309
X58-X59 Accidental exposure to other and unspecified factors	0.691	0.309
X50-X57 Overexertion, travel and privation	0.691	0.309
X40-X49 Accidental poisoning by and exposure to noxious substances	0.691	0.309
X30-X39 Exposure to forces of nature	0.691	0.309
X20-X29 Contact with venomous animals and plants	0.691	0.309
X10-X19 Contact with heat and hot substances	0.691	0.309
X00-X09 Exposure to smoke, fire and flames	0.691	0.309
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.691	0.309
W75-W84 Other accidental threats to breathing	0.691	0.309
W65-W74 Accidental drowning and submersion	0.691	0.309
W50-W64 Exposure to animate mechanical forces	0.691	0.309
V98-V99 Other and unspecified transport accidents	0.691	0.309
V95-V97 Air and space transport accidents	0.691	0.309
V90-V94 Water transport accidents	0.691	0.309
V80-V89 Other land transport accidents	0.691	0.309
V70-V79 Bus occupant injured in transport accident	0.691	0.309
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.691	0.309
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.691	0.309
V40-V49 Car occupant injured in transport accident	0.691	0.309
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.691	0.309
V20-V29 Motorcycle rider injured in transport accident	0.691	0.309
V01-V09 Pedestrian injured in transport accident	0.691	0.309
J34.2 Deviated nasal septum	0.687	0.313
H65-H75 Diseases of middle ear and mastoid	0.687	0.313
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.685	0.315
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.685	0.315
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.685	0.315
T84.3 Mechanical complication of other bone devices, implants and grafts	0.685	0.315
T84.2 Mechanical complication of internal fixation device of other bones	0.685	0.315
H94 Other disorders of ear in diseases classified elsewhere	0.685	0.315
N60-N64 Disorders of breast	0.683	0.317
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.682	0.318
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.682	0.318
K55 Vascular disorders of intestine	0.682	0.318
K43.0 Ventral hernia with obstruction, without gangrene	0.681	0.319
I05 Rheumatic mitral valve diseases	0.680	0.320
I52 Other heart disorders in diseases classified elsewhere	0.680	0.320
I48 Atrial fibrillation and flutter	0.680	0.320
I43 Cardiomyopathy in diseases classified elsewhere	0.680	0.320
I41 Myocarditis in diseases classified elsewhere	0.680	0.320
I40 Acute myocarditis	0.680	0.320
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.680	0.320
I37 Pulmonary valve disorders	0.680	0.320
I36 Nonrheumatic tricuspid valve disorders	0.680	0.320
I32 Pericarditis in diseases classified elsewhere	0.680	0.320
I30 Acute pericarditis	0.680	0.320
Z10 Routine general health check-up of defined subpopulation	0.680	0.320
E50-E64 Other nutritional deficiencies	0.679	0.321
E87.0 Hyperosmolality and hypernatraemia	0.679	0.321
M23.9 Internal derangement of knee, unspecified	0.678	0.322
M23.6 Other spontaneous disruption of ligament(s) of knee	0.678	0.322
M23.5 Chronic instability of knee	0.678	0.322
M23.1 Discoid meniscus (congenital)	0.678	0.322
M23.0 Cystic meniscus	0.678	0.322
C18.4 Transverse colon	0.677	0.323
I87 Other disorders of veins	0.676	0.324
J98.0 Diseases of bronchus, not elsewhere classified	0.676	0.324
K11 Diseases of salivary glands	0.676	0.324
Y40 Systemic antibiotics	0.675	0.325
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.675	0.325
Z83.6 Family history of diseases of the respiratory system	0.674	0.326
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.674	0.326
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.674	0.326
Z83.1 Family history of other infectious and parasitic diseases	0.674	0.326
Z83.0 Family history of human immunodeficiency virus [HIV]	0.674	0.326
K62.7 Radiation proctitis	0.672	0.328
K62.2 Anal prolapse	0.672	0.328
H61 Other disorders of external ear	0.672	0.328
X60-X84 Intentional self-harm	0.672	0.328
E06 Thyroiditis	0.671	0.329
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.671	0.329
E00 Congenital iodine-deficiency syndrome	0.671	0.329
E02 Subclinical iodine-deficiency hypothyroidism	0.671	0.329
Y51 Drugs primarily affecting the autonomic nervous system	0.671	0.329
Z11.2 Special screening examination for other bacterial diseases	0.671	0.329
I33 Acute and subacute endocarditis	0.671	0.329
G50-G59 Nerve, nerve root and plexus disorders	0.671	0.329
H90.5 Sensorineural hearing loss, unspecified	0.671	0.329
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.669	0.331
M40-M43 Deforming dorsopathies	0.669	0.331
J33 Nasal polyp	0.669	0.331
A49 Bacterial infection of unspecified site	0.668	0.332
D35.1 Parathyroid gland	0.667	0.333
Z72.1 Alcohol use	0.666	0.334
M50 Cervical disk disorders	0.666	0.334
Z29 Need for other prophylactic measures	0.666	0.334
Y84.6 Urinary catheterisation	0.666	0.334
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.665	0.335
D04.5 Skin of trunk	0.665	0.335
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.664	0.336
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.664	0.336
M80 Osteoporosis with pathological fracture	0.664	0.336
N37 Urethral disorders in diseases classified elsewhere	0.664	0.336
N33 Bladder disorders in diseases classified elsewhere	0.664	0.336
D22 Melanocytic naevi	0.664	0.336
J45.0 Predominantly allergic asthma	0.662	0.337
D23 Other benign neoplasms of skin	0.662	0.338
Z04.8 Examination and observation for other specified reasons	0.662	0.338
I07 Rheumatic tricuspid valve diseases	0.662	0.338
Z80.8 Family history of malignant neoplasm of other organs or systems	0.661	0.339
C62.9 Testis, unspecified	0.661	0.339
Y52 Agents primarily affecting the cardiovascular system	0.661	0.339
J20-J22 Other acute lower respiratory infections	0.661	0.339
H91.8 Other specified hearing loss	0.661	0.339
H91.3 Deaf mutism, not elsewhere classified	0.661	0.339
H91.2 Sudden idiopathic hearing loss	0.661	0.339
H91.1 Presbycusis	0.661	0.339
H91.0 Ototoxic hearing loss	0.661	0.339
M85 Other disorders of bone density and structure	0.660	0.339
Y60-Y69 Misadventures to patients during surgical and medical care	0.660	0.340
Z90.0 Acquired absence of part of head and neck	0.660	0.340
H25-H28 Disorders of lens	0.660	0.340
E85 Amyloidosis	0.660	0.340
E84 Cystic fibrosis	0.660	0.340
E79 Disorders of purine and pyrimidine metabolism	0.660	0.340
E77 Disorders of glycoprotein metabolism	0.660	0.340
E76 Disorders of glycosaminoglycan metabolism	0.660	0.340
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.660	0.340
E74 Other disorders of carbohydrate metabolism	0.660	0.340
E73 Lactose intolerance	0.660	0.340
E72 Other disorders of amino-acid metabolism	0.660	0.340
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.660	0.340

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations