TreeWAS – Variant ID: rs72877264

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Z92 Personal history of medical treatment	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.997	0.003
F10 Mental and behavioural disorders due to use of alcohol	0.996	0.004
Chapter II Neoplasms	0.995	0.005
Z92.2 Personal history of long-term (current) use of other medicaments	0.994	0.006
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.994	0.006
O60-O75 Complications of labour and delivery	0.994	0.006
Z95.5 Presence of coronary angioplasty implant and graft	0.992	0.008
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.992	0.008
I30-I52 Other forms of heart disease	0.991	0.009
Z95.1 Presence of aortocoronary bypass graft	0.989	0.011
Chapter XX External causes of morbidity and mortality	0.989	0.011
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.988	0.012
I71 Aortic aneurysm and dissection	0.986	0.014
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.985	0.015
Z70-Z76 Persons encountering health services in other circumstances	0.984	0.016
I25.1 Atherosclerotic heart disease	0.981	0.019
I25.9 Chronic ischaemic heart disease, unspecified	0.976	0.024
F10.1 Harmful use	0.975	0.025
C79 Secondary malignant neoplasm of other sites	0.972	0.028
Z92.4 Personal history of major surgery, not elsewhere classified	0.967	0.033
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.964	0.036
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.964	0.036
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.955	0.045
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.954	0.046
O36 Maternal care for other known or suspected foetal problems	0.953	0.047
F40-F48 Neurotic, stress-related and somatoform disorders	0.953	0.047
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.953	0.047
Chapter IV Endocrine, nutritional and metabolic diseases	0.950	0.050
T36-T50 Poisoning by drugs, medicaments and biological substances	0.946	0.054
I21 Acute myocardial infarction	0.946	0.054
R00 Abnormalities of heart beat	0.946	0.054
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.945	0.055
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.945	0.055
C77.3 Axillary and upper limb lymph nodes	0.943	0.057
C79.8 Secondary malignant neoplasm of other specified sites	0.943	0.057
E70-E90 Metabolic disorders	0.943	0.057
F10.2 Dependence syndrome	0.939	0.061
Z95.8 Presence of other cardiac and vascular implants and grafts	0.937	0.063
R00.2 Palpitations	0.936	0.064
Chapter VIII Diseases of the ear and mastoid process	0.934	0.066
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.933	0.067
Z92.1 Personal history of long-term (current) use of anticoagulants	0.932	0.068
S50-S59 Injuries to the elbow and forearm	0.932	0.068
O20-O29 Other maternal disorders predominantly related to pregnancy	0.927	0.073
C77.4 Inguinal and lower limb lymph nodes	0.927	0.073
I25.8 Other forms of chronic ischaemic heart disease	0.927	0.073
O70 Perineal laceration during delivery	0.926	0.074
I46 Cardiac arrest	0.925	0.075
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.924	0.076
C50-C50 Malignant neoplasm of breast	0.923	0.077
Z98 Other postsurgical states	0.922	0.078
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.921	0.079
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.921	0.079
I05-I09 Chronic rheumatic heart diseases	0.920	0.080
M05-M14 Inflammatory polyarthropathies	0.919	0.081
I95-I99 Other and unspecified disorders of the circulatory system	0.917	0.083
I21.1 Acute transmural myocardial infarction of inferior wall	0.913	0.087
E86 Volume depletion	0.912	0.088
O36.5 Maternal care for poor foetal growth	0.910	0.090
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.904	0.096
S52 Fracture of forearm	0.903	0.097
O46 Antepartum haemorrhage, not elsewhere classified	0.900	0.100
S60-S69 Injuries to the wrist and hand	0.899	0.101
Z80 Family history of malignant neoplasm	0.898	0.102
I77 Other disorders of arteries and arterioles	0.896	0.104
F10.0 Acute intoxication	0.896	0.104
M10 Gout	0.895	0.105
Z72 Problems related to lifestyle	0.893	0.107
Z99.3 Dependence on wheelchair	0.891	0.109
O36.8 Maternal care for other specified foetal problems	0.891	0.109
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.891	0.109
S20-S29 Injuries to the thorax	0.890	0.109
I51 Complications and ill-defined descriptions of heart disease	0.890	0.110
Z80.3 Family history of malignant neoplasm of breast	0.890	0.110
Z88.2 Personal history of allergy to sulphonamides	0.889	0.111
O70.0 First degree perineal laceration during delivery	0.886	0.114
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.885	0.115
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.880	0.120
M10.9 Gout, unspecified	0.879	0.121
O73 Retained placenta and membranes, without haemorrhage	0.878	0.122
M80-M85 Disorders of bone density and structure	0.876	0.124
O80-O84 Delivery	0.876	0.124
Z75 Problems related to medical facilities and other health care	0.874	0.126
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.874	0.126
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.873	0.127
C50 Malignant neoplasm of breast	0.872	0.128
M65-M68 Disorders of synovium and tendon	0.872	0.128
F40 Phobic anxiety disorders	0.872	0.128
I46.0 Cardiac arrest with successful resuscitation	0.871	0.129
F30-F39 Mood [affective] disorders	0.871	0.129
R00.0 Tachycardia, unspecified	0.870	0.130
I50 Heart failure	0.870	0.130
Z72.1 Alcohol use	0.868	0.132
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.868	0.132
Z91 Personal history of risk-factors, not elsewhere classified	0.865	0.135
Z92.0 Personal history of contraception	0.865	0.135
F41 Other anxiety disorders	0.865	0.135
O68 Labour and delivery complicated by foetal stress [distress]	0.861	0.139
I72 Other aneurysm	0.860	0.140
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.860	0.140
Z36 Antenatal screening	0.860	0.140
F10.3 Withdrawal state	0.860	0.140
Z99.1 Dependence on respirator	0.858	0.142
R00.1 Bradycardia, unspecified	0.858	0.142
W00-W19 Falls	0.858	0.142
D37-D48 Neoplasms of uncertain or unknown behaviour	0.857	0.143
Z98.8 Other specified postsurgical states	0.856	0.144
F80-F89 Disorders of psychological development	0.854	0.146
S52.5 Fracture of lower end of radius	0.851	0.148
M10.99 Gout, unspecified (Site unspecified)	0.851	0.149
H65-H75 Diseases of middle ear and mastoid	0.851	0.149
E83 Disorders of mineral metabolism	0.848	0.152
I35 Nonrheumatic aortic valve disorders	0.848	0.152
C51-C58 Malignant neoplasms of female genital organs	0.847	0.153
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.847	0.153
I51.7 Cardiomegaly	0.843	0.157
O41 Other disorders of amniotic fluid and membranes	0.841	0.159
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.840	0.160
O61 Failed induction of labour	0.839	0.161
I95 Hypotension	0.839	0.161
S10-S19 Injuries to the neck	0.837	0.163
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.836	0.164
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.836	0.164
Q20-Q28 Congenital malformations of the circulatory system	0.834	0.166
I34 Nonrheumatic mitral valve disorders	0.834	0.166
O43 Placental disorders	0.834	0.166
O46.9 Antepartum haemorrhage, unspecified	0.833	0.167
F60-F69 Disorders of adult personality and behaviour	0.832	0.168
Z88.7 Personal history of allergy to serum and vaccine	0.829	0.171
I08 Multiple valve diseases	0.829	0.171
O75 Other complications of labour and delivery, not elsewhere classified	0.827	0.173
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.826	0.174
Y52 Agents primarily affecting the cardiovascular system	0.826	0.174
I21.0 Acute transmural myocardial infarction of anterior wall	0.825	0.175
E87 Other disorders of fluid, electrolyte and acid-base balance	0.822	0.178
C50.1 Central portion of breast	0.821	0.179
Z98.2 Presence of cerebrospinal fluid drainage device	0.820	0.180
H90-H95 Other disorders of ear	0.818	0.182
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.816	0.183
D45 Polycythaemia vera	0.816	0.184
S52.50 Fracture of lower end of radius (closed)	0.815	0.185
F40.2 Specific (isolated) phobias	0.814	0.186
Z71.9 Counselling, unspecified	0.813	0.187
T90 Sequelae of injuries of head	0.811	0.189
O69 Labour and delivery complicated by umbilical cord complications	0.809	0.191
Z88.1 Personal history of allergy to other antibiotic agents	0.809	0.191
T93 Sequelae of injuries of lower limb	0.805	0.195
O62 Abnormalities of forces of labour	0.805	0.195
C79.9 Secondary malignant neoplasm, unspecified site	0.804	0.196
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.803	0.197
R02 Gangrene, not elsewhere classified	0.803	0.197
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.801	0.199
O94-O99 Other obstetric conditions, not elsewhere classified	0.800	0.200
Z91.5 Personal history of self-harm	0.799	0.201
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.799	0.201
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.798	0.201
S52.8 Fracture of other parts of forearm	0.798	0.202
T91 Sequelae of injuries of neck and trunk	0.797	0.203
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.797	0.203
Z75.1 Person awaiting admission to adequate facility elsewhere	0.796	0.204
O73.0 Retained placenta, without haemorrhage	0.795	0.205
Z87 Personal history of other diseases and conditions	0.795	0.205
M65 Synovitis and tenosynovitis	0.794	0.206
I25.2 Old myocardial infarction	0.793	0.207
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.793	0.207
Chapter VII Diseases of the eye and adnexa	0.791	0.209
O26 Maternal care for other conditions predominantly related to pregnancy	0.791	0.209
I10-I15 Hypertensive diseases	0.791	0.209
I36 Nonrheumatic tricuspid valve disorders	0.791	0.209
C80 Malignant neoplasm without specification of site	0.791	0.209
T85 Complications of other internal prosthetic devices, implants and grafts	0.790	0.210
C77.0 Lymph nodes of head, face and neck	0.790	0.210
O80 Single spontaneous delivery	0.789	0.211
R01 Cardiac murmurs and other cardiac sounds	0.789	0.211
Y43 Primarily systemic agents	0.788	0.212
Z99.2 Dependence on renal dialysis	0.784	0.216
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.783	0.217
Z37 Outcome of delivery	0.783	0.217
C79.2 Secondary malignant neoplasm of skin	0.782	0.218
Z94 Transplanted organ and tissue status	0.781	0.219
W20-W49 Exposure to inanimate mechanical forces	0.781	0.219
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.781	0.219
I25.5 Ischaemic cardiomyopathy	0.780	0.220
I21.4 Acute subendocardial myocardial infarction	0.778	0.222
O20 Haemorrhage in early pregnancy	0.778	0.222
O35 Maternal care for known or suspected foetal abnormality and damage	0.776	0.224
I71.0 Dissection of aorta [any part]	0.775	0.225
Y44 Agents primarily affecting blood constituents	0.775	0.225
T83.1 Mechanical complication of other urinary devices and implants	0.774	0.226
H66 Suppurative and unspecified otitis media	0.773	0.227
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.772	0.228
T92 Sequelae of injuries of upper limb	0.771	0.229
I60-I69 Cerebrovascular diseases	0.770	0.230
O40 Polyhydramnios	0.769	0.231
Y84.0 Cardiac catheterisation	0.769	0.231
I50.1 Left ventricular failure	0.768	0.232
Z60 Problems related to social environment	0.767	0.233
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.766	0.234
Z73 Problems related to life-management difficulty	0.766	0.234
X20-X29 Contact with venomous animals and plants	0.766	0.234
T20-T25 Burns and corrosions of external body surface, specified by site	0.766	0.234
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.765	0.235
S66 Injury of muscle and tendon at wrist and hand level	0.765	0.235
T59 Toxic effect of other gases, fumes and vapours	0.765	0.235
C50.9 Breast, unspecified	0.764	0.236
I77.1 Stricture of artery	0.763	0.237
Z83 Family history of other specific disorders	0.761	0.239
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.761	0.239
T15-T19 Effects of foreign body entering through natural orifice	0.760	0.240
I42 Cardiomyopathy	0.760	0.240
Z63 Other problems related to primary support group, including family circumstances	0.759	0.241
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.759	0.241
H92 Otalgia and effusion of ear	0.758	0.242
O23 Infections of genito-urinary tract in pregnancy	0.758	0.242
Z96 Presence of other functional implants	0.758	0.242
M10.96 Gout, unspecified (Lower leg)	0.758	0.242
R05 Cough	0.755	0.245
R03 Abnormal blood-pressure reading, without diagnosis	0.755	0.245
I08.0 Disorders of both mitral and aortic valves	0.755	0.245
M45-M49 Spondylopathies	0.754	0.246
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.754	0.246
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.753	0.247
O00-O08 Pregnancy with abortive outcome	0.751	0.249
F81 Specific developmental disorders of scholastic skills	0.750	0.250
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.750	0.250
M11 Other crystal arthropathies	0.750	0.250
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.749	0.250
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.749	0.251
M60-M63 Disorders of muscles	0.748	0.251
I05 Rheumatic mitral valve diseases	0.748	0.252
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.748	0.252
Z29 Need for other prophylactic measures	0.747	0.253
Z81 Family history of mental and behavioural disorders	0.746	0.254
T39.0 Salicylates	0.744	0.256
D69 Purpura and other haemorrhagic conditions	0.744	0.256
C77.8 Lymph nodes of multiple regions	0.744	0.256
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.744	0.256
I30 Acute pericarditis	0.743	0.257
Z88.0 Personal history of allergy to penicillin	0.743	0.257
C56 Malignant neoplasm of ovary	0.741	0.259
V80-V89 Other land transport accidents	0.741	0.259
I34.0 Mitral (valve) insufficiency	0.740	0.260
R50-R69 General symptoms and signs	0.739	0.261
F10.4 Withdrawal state with delirium	0.739	0.261
W19 Unspecified fall	0.739	0.261
I70 Atherosclerosis	0.738	0.262
V40-V49 Car occupant injured in transport accident	0.737	0.263
I95.9 Hypotension, unspecified	0.737	0.263
R42 Dizziness and giddiness	0.737	0.263
I78 Diseases of capillaries	0.736	0.264
Y84.6 Urinary catheterisation	0.736	0.264
I95.1 Orthostatic hypotension	0.736	0.264
I74 Arterial embolism and thrombosis	0.736	0.264
X60-X84 Intentional self-harm	0.735	0.265
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.734	0.265
Z36.9 Antenatal screening, unspecified	0.734	0.266
E40-E46 Malnutrition	0.732	0.268
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.732	0.268
M81 Osteoporosis without pathological fracture	0.732	0.268
Chapter XXII Codes for special purposes	0.732	0.268
Z84 Family history of other conditions	0.731	0.269
R55 Syncope and collapse	0.731	0.269
Z74 Problems related to care-provider dependency	0.730	0.270
M00-M03 Infectious arthropathies	0.729	0.270
F32 Depressive episode	0.729	0.271
E87.6 Hypokalaemia	0.729	0.271
O61.0 Failed medical induction of labour	0.728	0.272
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.728	0.272
H52 Disorders of refraction and accommodation	0.727	0.272
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.727	0.273
S60 Superficial injury of wrist and hand	0.727	0.273
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.727	0.273
S64 Injury of nerves at wrist and hand level	0.727	0.273
I71.3 Abdominal aortic aneurysm, ruptured	0.726	0.274
O44 Placenta praevia	0.725	0.275
S62 Fracture at wrist and hand level	0.725	0.275
S52.80 Fracture of other parts of forearm (closed)	0.723	0.277
E83.4 Disorders of magnesium metabolism	0.722	0.278
D69.6 Thrombocytopenia, unspecified	0.721	0.279
T88 Other complications of surgical and medical care, not elsewhere classified	0.721	0.279
S19 Other and unspecified injuries of neck	0.721	0.279
F00-F09 Organic, including symptomatic, mental disorders	0.721	0.279
V10-V19 Pedal cyclist injured in transport accident	0.721	0.279
M91-M94 Chondropathies	0.720	0.280
F99-F99 Unspecified mental disorder	0.719	0.281
O41.0 Oligohydramnios	0.718	0.281
T31 Burns classified according to extent of body surface involved	0.718	0.282
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.718	0.282
S27 Injury of other and unspecified intrathoracic organs	0.718	0.282
I00-I02 Acute rheumatic fever	0.717	0.283
O85-O92 Complications predominantly related to the puerperium	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Z92.9 Personal history of medical treatment, unspecified	0.717	0.283
Z92.5 Personal history of rehabilitation measures	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.716	0.284
O16 Unspecified maternal hypertension	0.716	0.284
M85 Other disorders of bone density and structure	0.716	0.284
O47 False labour	0.716	0.284
I20 Angina pectoris	0.715	0.285
Z88.3 Personal history of allergy to other anti-infective agents	0.715	0.285
C45 Mesothelioma	0.715	0.285
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.715	0.285
F18 Mental and behavioural disorders due to use of volatile solvents	0.715	0.285
F16 Mental and behavioural disorders due to use of hallucinogens	0.715	0.285
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.715	0.285
F14 Mental and behavioural disorders due to use of cocaine	0.715	0.285
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.715	0.285
F12 Mental and behavioural disorders due to use of cannabinoids	0.715	0.285
F11 Mental and behavioural disorders due to use of opioids	0.715	0.285
I50.9 Heart failure, unspecified	0.715	0.285
T79-T79 Certain early complications of trauma	0.715	0.285
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.715	0.285
S20 Superficial injury of thorax	0.714	0.285
F10.9 Unspecified mental and behavioural disorder	0.714	0.286
F10.8 Other mental and behavioural disorders	0.714	0.286
F10.7 Residual and late-onset psychotic disorder	0.714	0.286
F10.6 Amnesic syndrome	0.714	0.286
F10.5 Psychotic disorder	0.714	0.286
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.714	0.286
O20.9 Haemorrhage in early pregnancy, unspecified	0.714	0.286
Z92.8 Personal history of other medical treatment	0.714	0.286
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
C76 Malignant neoplasm of other and ill-defined sites	0.713	0.287
O74 Complications of anaesthesia during labour and delivery	0.713	0.287
O71 Other obstetric trauma	0.713	0.287
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.713	0.287
O65 Obstructed labour due to maternal pelvic abnormality	0.713	0.287
O60 Preterm delivery	0.713	0.287
F60 Specific personality disorders	0.712	0.288
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.711	0.289
Q24 Other congenital malformations of heart	0.711	0.289
O45 Premature separation of placenta [abruptio placentae]	0.711	0.289
O33 Maternal care for known or suspected disproportion	0.711	0.289
O31 Complications specific to multiple gestation	0.711	0.289
Z87.0 Personal history of diseases of the respiratory system	0.711	0.289
I12 Hypertensive renal disease	0.711	0.289
I52 Other heart disorders in diseases classified elsewhere	0.711	0.289
I48 Atrial fibrillation and flutter	0.711	0.289
I43 Cardiomyopathy in diseases classified elsewhere	0.711	0.289
I41 Myocarditis in diseases classified elsewhere	0.711	0.289
I40 Acute myocarditis	0.711	0.289
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.711	0.289
I37 Pulmonary valve disorders	0.711	0.289
I32 Pericarditis in diseases classified elsewhere	0.711	0.289
I51.0 Cardiac septal defect, acquired	0.711	0.289
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.711	0.289
C77.1 Intrathoracic lymph nodes	0.711	0.289
M80 Osteoporosis with pathological fracture	0.710	0.290
H80-H83 Diseases of inner ear	0.710	0.290
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.709	0.291
Y35-Y36 Legal intervention and operations of war	0.709	0.291
Y10-Y34 Event of undetermined intent	0.709	0.291
Y00-Y09 Assault	0.709	0.291
X85-X99 Assault	0.709	0.291
X58-X59 Accidental exposure to other and unspecified factors	0.709	0.291
X50-X57 Overexertion, travel and privation	0.709	0.291
X30-X39 Exposure to forces of nature	0.709	0.291
X10-X19 Contact with heat and hot substances	0.709	0.291
X00-X09 Exposure to smoke, fire and flames	0.709	0.291
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.709	0.291
W75-W84 Other accidental threats to breathing	0.709	0.291
W65-W74 Accidental drowning and submersion	0.709	0.291
W50-W64 Exposure to animate mechanical forces	0.709	0.291
V98-V99 Other and unspecified transport accidents	0.709	0.291
V95-V97 Air and space transport accidents	0.709	0.291
V90-V94 Water transport accidents	0.709	0.291
V70-V79 Bus occupant injured in transport accident	0.709	0.291
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.709	0.291
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.709	0.291
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.709	0.291
V01-V09 Pedestrian injured in transport accident	0.709	0.291
X40-X49 Accidental poisoning by and exposure to noxious substances	0.707	0.292
C80.0 Malignant neoplasm, primary site unknown, so stated	0.707	0.293
I71.8 Aortic aneurysm of unspecified site, ruptured	0.707	0.293
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.707	0.293
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.707	0.293
I71.1 Thoracic aortic aneurysm, ruptured	0.707	0.293
O32 Maternal care for known or suspected malpresentation of foetus	0.706	0.293
C43-C44 Melanoma and other malignant neoplasms of skin	0.706	0.294
I25.3 Aneurysm of heart	0.706	0.294
Z76 Persons encountering health services in other circumstances	0.706	0.294
Z70 Counselling related to sexual attitude, behaviour and orientation	0.706	0.294
O70.2 Third degree perineal laceration during delivery	0.705	0.295
Z96.8 Presence of other specified functional implants	0.704	0.295
S29 Other and unspecified injuries of thorax	0.704	0.296
M66 Spontaneous rupture of synovium and tendon	0.704	0.296
M65.9 Synovitis and tenosynovitis, unspecified	0.704	0.296
I77.8 Other specified disorders of arteries and arterioles	0.703	0.297
I45 Other conduction disorders	0.703	0.297
F33 Recurrent depressive disorder	0.702	0.298
C50.5 Lower-outer quadrant of breast	0.702	0.298
I60 Subarachnoid haemorrhage	0.702	0.298
Chapter VI Diseases of the nervous system	0.702	0.298
Y41 Other systemic anti-infectives and antiparasitics	0.701	0.299
Q23 Congenital malformations of aortic and mitral valves	0.701	0.299
I77.9 Disorder of arteries and arterioles, unspecified	0.700	0.300
H66.9 Otitis media, unspecified	0.699	0.301
H49 Paralytic strabismus	0.699	0.301
E83.1 Disorders of iron metabolism	0.699	0.301
Z95.4 Presence of other heart-valve replacement	0.699	0.301
M05 Seropositive rheumatoid arthritis	0.699	0.301
S65 Injury of blood vessels at wrist and hand level	0.698	0.302
E73 Lactose intolerance	0.698	0.302
C79.6 Secondary malignant neoplasm of ovary	0.697	0.303
H52.1 Myopia	0.697	0.303
T51 Toxic effect of alcohol	0.695	0.305
Z37.0 Single live birth	0.695	0.305
T46 Poisoning by agents primarily affecting the cardiovascular system	0.694	0.306
Q80-Q89 Other congenital malformations	0.693	0.306
Z80.6 Family history of leukaemia	0.693	0.307
I46.9 Cardiac arrest, unspecified	0.693	0.307
I35.2 Aortic (valve) stenosis with insufficiency	0.692	0.308
C77.5 Intrapelvic lymph nodes	0.691	0.309
Z99.9 Dependence on unspecified enabling machine and device	0.691	0.309
Z99.4 Dependence on artificial heart	0.691	0.309
Z99.0 Dependence on aspirator	0.691	0.309
O80.9 Single spontaneous delivery, unspecified	0.691	0.309
R47-R49 Symptoms and signs involving speech and voice	0.690	0.309
O21 Excessive vomiting in pregnancy	0.689	0.311
O75.0 Maternal distress during labour and delivery	0.688	0.311
H92.0 Otalgia	0.688	0.312
I72.3 Aneurysm of iliac artery	0.688	0.312
T83.0 Mechanical complication of urinary (indwelling) catheter	0.687	0.313
Z95.3 Presence of xenogenic heart valve	0.686	0.313
T66-T78 Other and unspecified effects of external causes	0.686	0.314
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.686	0.314
C77.9 Lymph node, unspecified	0.685	0.315
T98 Sequelae of other and unspecified effects of external causes	0.685	0.315
T95 Sequelae of burns, corrosions and frostbite	0.685	0.315
T94 Sequelae of injuries involving multiple and unspecified body regions	0.685	0.315
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.685	0.315
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.685	0.315
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.685	0.315
E87.5 Hyperkalaemia	0.685	0.315
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.684	0.316
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.684	0.316
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.683	0.316
O36.4 Maternal care for intra-uterine death	0.683	0.316
O36.3 Maternal care for signs of foetal hypoxia	0.683	0.316
O36.2 Maternal care for hydrops foetalis	0.683	0.316
O36.1 Maternal care for other isoimmunisation	0.683	0.316
O72 Postpartum haemorrhage	0.683	0.317
F48 Other neurotic disorders	0.683	0.317
F44 Dissociative [conversion] disorders	0.683	0.317
F42 Obsessive-compulsive disorder	0.683	0.317
O43.8 Other placental disorders	0.683	0.317
I72.4 Aneurysm of artery of lower extremity	0.683	0.317
T59.8 Other specified gases, fumes and vapours	0.682	0.318
E89.0 Postprocedural hypothyroidism	0.682	0.318
Z95.2 Presence of prosthetic heart valve	0.681	0.319
Y51 Drugs primarily affecting the autonomic nervous system	0.681	0.319
I64 Stroke, not specified as haemorrhage or infarction	0.680	0.320
Z36.0 Antenatal screening for chromosomal anomalies	0.680	0.320
H74 Other disorders of middle ear and mastoid	0.680	0.320
M07 Psoriatic and enteropathic arthropathies	0.679	0.321
Z57 Occupational exposure to risk-factors	0.679	0.321
I35.0 Aortic (valve) stenosis	0.679	0.321
I38 Endocarditis, valve unspecified	0.678	0.321
T43.3 Phenothiazine antipsychotics and neuroleptics	0.679	0.321
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.678	0.322
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.678	0.322
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.678	0.322
T41 Poisoning by anaesthetics and therapeutic gases	0.678	0.322
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.678	0.322
T36 Poisoning by systemic antibiotics	0.678	0.322
I21.X Presumed acute myicardial infaction (unconfirmed)	0.678	0.322
I21.3 Acute transmural myocardial infarction of unspecified site	0.678	0.322
R95-R99 Ill-defined and unknown causes of mortality	0.677	0.323
S52.6 Fracture of lower end of both ulna and radius	0.677	0.323
R53 Malaise and fatigue	0.677	0.323
R01.1 Cardiac murmur, unspecified	0.677	0.323
Z31 Procreative management	0.676	0.324
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.676	0.324
F41.9 Anxiety disorder, unspecified	0.676	0.324
E85 Amyloidosis	0.676	0.324
E84 Cystic fibrosis	0.676	0.324
E79 Disorders of purine and pyrimidine metabolism	0.676	0.324
E77 Disorders of glycoprotein metabolism	0.676	0.324

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations