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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs176095
log Bayes Factor = 360.117
Chromosome 6   position 32,158,319  (GRCh37) Explore rs176095 on Ensembl!
Variant rs176095 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.999 0.001 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.999 0.001 0.000
L40.5 Arthropathic psoriasis
0.999 0.001 0.000
N00-N08 Glomerular diseases
0.999 0.001 0.000
K75 Other inflammatory liver diseases
0.998 0.002 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.997 0.003 0.000
M05 Seropositive rheumatoid arthritis
0.001 0.003 0.996
D64.9 Anaemia, unspecified
0.997 0.003 0.000
G51 Facial nerve disorders
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
E10.1 With ketoacidosis
0.997 0.003 0.000
N04 Nephrotic syndrome
0.996 0.004 0.000
D60-D64 Aplastic and other anaemias
0.996 0.004 0.000
M05-M14 Inflammatory polyarthropathies
0.002 0.004 0.994
E03 Other hypothyroidism
0.996 0.004 0.000
D64 Other anaemias
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
M20.1 Hallux valgus (acquired)
0.000 0.006 0.994
G56 Mononeuropathies of upper limb
0.993 0.007 0.000
E14.3 With ophthalmic complications
0.992 0.008 0.000
G56.0 Carpal tunnel syndrome
0.992 0.008 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.992 0.008 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.991 0.009 0.000
N04.9 Unspecified
0.991 0.009 0.000
E20-E35 Disorders of other endocrine glands
0.991 0.009 0.000
N17-N19 Renal failure
0.991 0.009 0.000
N18 Chronic renal failure
0.990 0.010 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.010 0.990
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.989 0.011 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.012 0.988
E03.9 Hypothyroidism, unspecified
0.987 0.013 0.000
K75.8 Other specified inflammatory liver diseases
0.987 0.013 0.000
N05 Unspecified nephritic syndrome
0.987 0.013 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.986 0.014 0.000
E14.9 Without complications
0.986 0.014 0.000
Chapter II Neoplasms
0.986 0.014 0.000
G51.0 Bell's palsy
0.985 0.015 0.000
I74 Arterial embolism and thrombosis
0.984 0.016 0.000
N18.9 Chronic renal failure, unspecified
0.983 0.017 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.020 0.980
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.980 0.020 0.000
D50-D53 Nutritional anaemias
0.980 0.020 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.976 0.024 0.000
K90.9 Intestinal malabsorption, unspecified
0.973 0.027 0.000
D51 Vitamin B12 deficiency anaemia
0.973 0.027 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.029 0.971
C15-C26 Malignant neoplasms of digestive organs
0.964 0.036 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.963 0.037 0.000
E27 Other disorders of adrenal gland
0.962 0.038 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.961 0.039 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.960 0.040 0.000
K31 Other diseases of stomach and duodenum
0.958 0.042 0.000
E27.1 Primary adrenocortical insufficiency
0.957 0.043 0.000
K31.8 Other specified diseases of stomach and duodenum
0.957 0.043 0.000
G51.9 Disorder of facial nerve, unspecified
0.957 0.043 0.000
C85.1 B-cell lymphoma, unspecified
0.956 0.044 0.000
M06.3 Rheumatoid nodule
0.000 0.046 0.954
E10.2 With renal complications
0.954 0.046 0.000
L10-L14 Bullous disorders
0.951 0.049 0.000
K75.4 Autoimmune hepatitis
0.949 0.051 0.000
M45 Ankylosing spondylitis
0.000 0.055 0.945
K25 Gastric ulcer
0.944 0.056 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.944 0.056 0.000
E11.3 With ophthalmic complications
0.943 0.057 0.000
C91 Lymphoid leukaemia
0.943 0.057 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.943 0.057 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.942 0.058 0.000
Q50-Q56 Congenital malformations of genital organs
0.939 0.061 0.000
K73 Chronic hepatitis, not elsewhere classified
0.936 0.064 0.000
I77 Other disorders of arteries and arterioles
0.934 0.066 0.000
N05.2 Diffuse membranous glomerulonephritis
0.934 0.066 0.000
C15 Malignant neoplasm of oesophagus
0.933 0.067 0.000
L13 Other bullous disorders
0.931 0.068 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.927 0.073 0.000
L40.0 Psoriasis vulgaris
0.925 0.075 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.922 0.078 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.078 0.922
Q60-Q64 Congenital malformations of the urinary system
0.921 0.079 0.000
K50-K52 Noninfective enteritis and colitis
0.914 0.081 0.004
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.918 0.082 0.000
L13.0 Dermatitis herpetiformis
0.918 0.082 0.000
C83.3 Large cell (diffuse)
0.915 0.085 0.000
C20 Malignant neoplasm of rectum
0.913 0.087 0.000
E14.8 With unspecified complications
0.912 0.088 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.088 0.912
E11.1 With ketoacidosis
0.912 0.088 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.911 0.089 0.000
L50-L54 Urticaria and erythema
0.911 0.089 0.000
K52 Other non-infective gastro-enteritis and colitis
0.908 0.091 0.001
K72 Hepatic failure, not elsewhere classified
0.908 0.092 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.908 0.092 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.908 0.092 0.000
I60-I69 Cerebrovascular diseases
0.908 0.092 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.904 0.096 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.903 0.097 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.900 0.100 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.101 0.899
I77.1 Stricture of artery
0.897 0.103 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.897 0.103 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.894 0.106 0.000
D80-D89 Certain disorders involving the immune mechanism
0.894 0.106 0.000
C34 Malignant neoplasm of bronchus and lung
0.893 0.107 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.892 0.108 0.000
N18.2 Chronic kidney disease, stage 2
0.892 0.108 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.891 0.109 0.000
I73 Other peripheral vascular diseases
0.891 0.109 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.891 0.109 0.000
I65.2 Occlusion and stenosis of carotid artery
0.888 0.112 0.000
C91.1 Chronic lymphocytic leukaemia
0.886 0.114 0.000
E11.2 With renal complications
0.885 0.115 0.000
N05.1 Focal and segmental glomerular lesions
0.885 0.115 0.000
K25.3 Acute without haemorrhage or perforation
0.884 0.116 0.000
I63 Cerebral infarction
0.884 0.116 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.882 0.118 0.000
E10.4 With neurological complications
0.882 0.118 0.000
I27 Other pulmonary heart diseases
0.878 0.122 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.123 0.877
N18.4 Chronic kidney disease, stage 4
0.877 0.123 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.876 0.124 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.128 0.872
E11.5 With peripheral circulatory complications
0.869 0.131 0.000
C34.3 Lower lobe, bronchus or lung
0.869 0.131 0.000
L52 Erythema nodosum
0.867 0.133 0.000
Q43 Other congenital malformations of intestine
0.867 0.133 0.000
I74.5 Embolism and thrombosis of iliac artery
0.865 0.135 0.000
K29 Gastritis and duodenitis
0.864 0.136 0.000
C15.4 Middle third of oesophagus
0.862 0.138 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.139 0.861
Q54 Hypospadias
0.859 0.141 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.141 0.859
I27.9 Pulmonary heart disease, unspecified
0.856 0.144 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.855 0.145 0.000
K29.5 Chronic gastritis, unspecified
0.851 0.149 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.851 0.149 0.000
L44 Other papulosquamous disorders
0.850 0.150 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.847 0.153 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.846 0.154 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.846 0.154 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.846 0.154 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.844 0.156 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.844 0.156 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.158 0.842
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.841 0.159 0.000
E11.4 With neurological complications
0.841 0.159 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.840 0.160 0.000
K72.9 Hepatic failure, unspecified
0.839 0.161 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.839 0.161 0.000
K74 Fibrosis and cirrhosis of liver
0.837 0.163 0.000
E10.8 With unspecified complications
0.837 0.163 0.000
I05-I09 Chronic rheumatic heart diseases
0.835 0.165 0.000
E21.0 Primary hyperparathyroidism
0.833 0.167 0.000
N05.8 Other
0.832 0.168 0.000
L40.1 Generalised pustular psoriasis
0.832 0.168 0.000
I73.9 Peripheral vascular disease, unspecified
0.831 0.169 0.000
D53 Other nutritional anaemias
0.830 0.170 0.000
L40.3 Pustulosis palmaris et plantaris
0.826 0.173 0.000
E50-E64 Other nutritional deficiencies
0.826 0.174 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.824 0.176 0.000
G20-G26 Extrapyramidal and movement disorders
0.821 0.179 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.179 0.821
E14.4 With neurological complications
0.820 0.180 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.182 0.818
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.818 0.182 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.818 0.182 0.000
D55-D59 Haemolytic anaemias
0.818 0.182 0.000
C38.4 Pleura
0.814 0.186 0.000
E24 Cushing's syndrome
0.813 0.187 0.000
G50 Disorders of trigeminal nerve
0.812 0.188 0.000
N04.1 Focal and segmental glomerular lesions
0.812 0.188 0.000
D80 Immunodeficiency with predominantly antibody defects
0.811 0.189 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.811 0.189 0.000
D70 Agranulocytosis
0.810 0.190 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.810 0.190 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.803 0.197 0.000
M20 Acquired deformities of fingers and toes
0.000 0.198 0.802
Chapter I Certain infectious and parasitic diseases
0.801 0.199 0.000
E14.2 Withrenal complications
0.801 0.199 0.000
E21.3 Hyperparathyroidism, unspecified
0.801 0.199 0.000
K73.9 Chronic hepatitis, unspecified
0.800 0.200 0.000
Q00-Q07 Congenital malformations of the nervous system
0.798 0.201 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.798 0.202 0.000
G56.4 Causalgia
0.798 0.202 0.000
Q80-Q89 Other congenital malformations
0.797 0.203 0.000
N18.0 End-stage renal disease
0.795 0.205 0.000
Q63 Other congenital malformations of kidney
0.795 0.205 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.795 0.205 0.000
K29.8 Duodenitis
0.794 0.206 0.000
C91.0 Acute lymphoblastic leukaemia
0.794 0.206 0.000
E03.1 Congenital hypothyroidism without goitre
0.794 0.206 0.000
C95 Leukaemia of unspecified cell type
0.790 0.210 0.000
C34.2 Middle lobe, bronchus or lung
0.788 0.212 0.000
G59.0 Diabetic mononeuropathy
0.787 0.213 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.784 0.216 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.217 0.783
E21.2 Other hyperparathyroidism
0.782 0.218 0.000
C22.9 Liver, unspecified
0.782 0.218 0.000
E14.1 With ketoacidosis
0.781 0.219 0.000
N25-N29 Other disorders of kidney and ureter
0.781 0.219 0.000
E11.6 With other specified complications
0.781 0.219 0.000
E10.0 With coma
0.779 0.220 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.779 0.221 0.000
N04.0 Minor glomerular abnormality
0.778 0.221 0.000
C82.2 Large cell, follicular
0.777 0.223 0.000
C22.1 Intrahepatic bile duct carcinoma
0.774 0.226 0.000
K74.6 Other and unspecified cirrhosis of liver
0.772 0.228 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.772 0.228 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.229 0.771
C32 Malignant neoplasm of larynx
0.770 0.230 0.000
C23 Malignant neoplasm of gallbladder
0.770 0.230 0.000
E34 Other endocrine disorders
0.769 0.231 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.768 0.232 0.000
Q54.1 Hypospadias, penile
0.767 0.233 0.000
N04.2 Diffuse membranous glomerulonephritis
0.767 0.233 0.000
E10.7 With multiple complications
0.766 0.234 0.000
I74.8 Embolism and thrombosis of other arteries
0.765 0.234 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.763 0.237 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.010 0.239 0.751
Q38 Other congenital malformations of tongue, mouth and pharynx
0.759 0.241 0.000
M45-M49 Spondylopathies
0.005 0.241 0.755
E31 Polyglandular dysfunction
0.759 0.241 0.000
I63.8 Other cerebral infarction
0.758 0.242 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.755 0.245 0.000
L42 Pityriasis rosea
0.755 0.245 0.000
K74.0 Hepatic fibrosis
0.755 0.245 0.000
E16.1 Other hypoglycaemia
0.754 0.245 0.000
N18.1 Chronic kidney disease, stage 1
0.753 0.247 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.752 0.248 0.000
E14.5 With peripheral circulatory complications
0.752 0.248 0.000
C88 Malignant immunoproliferative diseases
0.751 0.248 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.250 0.750
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.750 0.250 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.749 0.251 0.000
C15.9 Oesophagus, unspecified
0.749 0.251 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.252 0.748
N08.5 Glomerular disorders in systemic connective tissue disorders
0.746 0.254 0.000
I07 Rheumatic tricuspid valve diseases
0.746 0.254 0.000
K75.0 Abscess of liver
0.746 0.254 0.000
E03.8 Other specified hypothyroidism
0.745 0.255 0.000
C15.1 Thoracic part of oesophagus
0.744 0.256 0.000
C15.0 Cervical part of oesophagus
0.744 0.256 0.000
N18.3 Chronic kidney disease, stage 3
0.743 0.257 0.000
L44.0 Pityriasis rubra pilaris
0.743 0.257 0.000
C60-C63 Malignant neoplasms of male genital organs
0.742 0.258 0.000
M20-M25 Other joint disorders
0.001 0.258 0.742
Q51 Congenital malformations of uterus and cervix
0.741 0.259 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.741 0.259 0.000
K75.9 Inflammatory liver disease, unspecified
0.739 0.261 0.000
Q52 Other congenital malformations of female genitalia
0.739 0.261 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.262 0.738
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.735 0.264 0.000
L43 Lichen planus
0.735 0.265 0.000
G24 Dystonia
0.734 0.266 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.267 0.733
E07 Other disorders of thyroid
0.732 0.268 0.000
K25.0 Acute with haemorrhage
0.732 0.268 0.000
G30-G32 Other degenerative diseases of the nervous system
0.732 0.268 0.000
B35-B49 Mycoses
0.730 0.270 0.000
C34.8 Overlapping lesion of bronchus and lung
0.730 0.270 0.000
E20 Hypoparathyroidism
0.730 0.270 0.000
E23 Hypofunction and other disorders of pituitary gland
0.730 0.270 0.000
E06 Thyroiditis
0.730 0.270 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.730 0.270 0.000
C21 Malignant neoplasm of anus and anal canal
0.730 0.270 0.000
Q44.6 Cystic disease of liver
0.729 0.271 0.000
M20.3 Other deformity of hallux (acquired)
0.000 0.272 0.728
K72.1 Chronic hepatic failure
0.727 0.273 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.273 0.726
K25.5 Chronic or unspecified with perforation
0.726 0.274 0.000
C37 Malignant neoplasm of thymus
0.724 0.276 0.000
B02 Zoster [herpes zoster]
0.723 0.277 0.000
C15.5 Lower third of oesophagus
0.723 0.277 0.000
D53.9 Nutritional anaemia, unspecified
0.722 0.277 0.000
C38.3 Mediastinum, part unspecified
0.722 0.278 0.000
Q64 Other congenital malformations of urinary system
0.722 0.278 0.000
D59 Acquired haemolytic anaemia
0.721 0.279 0.000
K31.3 Pylorospasm, not elsewhere classified
0.720 0.279 0.000
I73.0 Raynaud's syndrome
0.720 0.280 0.000
L53 Other erythematous conditions
0.720 0.280 0.000
C84.4 Peripheral T-cell lymphoma
0.719 0.281 0.000
C22.0 Liver cell carcinoma
0.718 0.282 0.000
M35 Other systemic involvement of connective tissue
0.001 0.283 0.716
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.716
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.716 0.284 0.000
N06 Isolated proteinuria with specified morphological lesion
0.716 0.284 0.000
N01 Rapidly progressive nephritic syndrome
0.716 0.284 0.000
N00 Acute nephritic syndrome
0.716 0.284 0.000
K75.2 Nonspecific reactive hepatitis
0.715 0.284 0.000
K75.1 Phlebitis of portal vein
0.715 0.284 0.000
Q35-Q37 Cleft lip and cleft palate
0.715 0.285 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.715 0.285 0.000
M11 Other crystal arthropathies
0.002 0.285 0.713
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.285 0.714
M05.2 Rheumatoid vasculitis
0.001 0.285 0.714
M05.1 Rheumatoid lung disease
0.001 0.285 0.714
M05.0 Felty's syndrome
0.001 0.285 0.714
G51.4 Facial myokymia
0.715 0.285 0.000
G51.2 Melkersson's syndrome
0.715 0.285 0.000
G51.1 Geniculate ganglionitis
0.715 0.285 0.000
K29.7 Gastritis, unspecified
0.714 0.286 0.000
N04.8 Other
0.714 0.286 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.714 0.286 0.000
N04.6 Dense deposit disease
0.714 0.286 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.714 0.286 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.714 0.286 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.714 0.286 0.000
E03.5 Myxoedema coma
0.714 0.286 0.000
E03.4 Atrophy of thyroid (acquired)
0.714 0.286 0.000
E03.3 Postinfectious hypothyroidism
0.714 0.286 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.714 0.286 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.002 0.286 0.712
D64.4 Congenital dyserythropoietic anaemia
0.714 0.286 0.000
D64.3 Other sideroblastic anaemias
0.714 0.286 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.714 0.286 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.714 0.286 0.000
D64.0 Hereditary sideroblastic anaemia
0.714 0.286 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.286 0.714
Q40 Other congenital malformations of upper alimentary tract
0.713 0.287 0.000
K71 Toxic liver disease
0.712 0.288 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.711 0.289 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.711 0.289 0.000
C94 Other leukaemias of specified cell type
0.711 0.289 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.710 0.289 0.000
E32 Diseases of thymus
0.710 0.289 0.000
E30 Disorders of puberty, not elsewhere classified
0.710 0.289 0.000
E25 Adrenogenital disorders
0.710 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C85.0 Lymphosarcoma
0.709 0.291 0.000
C86 Other specified types of T/NK-cell lymphoma
0.709 0.291 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.291 0.709
K31.5 Obstruction of duodenum
0.708 0.292 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.708 0.292 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.708 0.292 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.708 0.292 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.707 0.293 0.000
N05.6 Dense deposit disease
0.707 0.293 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.707 0.293 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.707 0.293 0.000
N05.0 Minor glomerular abnormality
0.707 0.293 0.000
C91.9 Lymphoid leukaemia, unspecified
0.707 0.293 0.000
M35.3 Polymyalgia rheumatica
0.000 0.293 0.707
N08.8 Glomerular disorders in other diseases classified elsewhere
0.707 0.293 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.707 0.293 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.707 0.293 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.707 0.293 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.707 0.293 0.000
D83 Common variable immunodeficiency
0.707 0.293 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.704 0.296 0.000
G00 Bacterial meningitis, not elsewhere classified
0.704 0.296 0.000
C84.5 Other and unspecified T-cell lymphomas
0.704 0.296 0.000
M12 Other specific arthropathies
0.002 0.297 0.701
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.297 0.703
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.297 0.703
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.297 0.703
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.297 0.703
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.297 0.703
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.297 0.703
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.297 0.703
I06 Rheumatic aortic valve diseases
0.703 0.297 0.000
K27 Peptic ulcer, site unspecified
0.702 0.298 0.000
Q45 Other congenital malformations of digestive system
0.702 0.298 0.000
E13 Other specified diabetes mellitus
0.701 0.299 0.000
B02.9 Zoster without complication
0.700 0.300 0.000
N10-N16 Renal tubulo-interstitial diseases
0.699 0.301 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.302 0.698
B07 Viral warts
0.698 0.302 0.000
D51.2 Transcobalamin II deficiency
0.697 0.303 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.697 0.303 0.000
Chapter XXII Codes for special purposes
0.697 0.303 0.000
E40-E46 Malnutrition
0.696 0.303 0.000
I00-I02 Acute rheumatic fever
0.696 0.304 0.000
E10.6 With other specified complications
0.696 0.304 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.696 0.304 0.000
Q44.5 Other congenital malformations of bile ducts
0.696 0.304 0.000
I27.0 Primary pulmonary hypertension
0.695 0.305 0.000
E24.0 Pituitary-dependent Cushing's disease
0.694 0.306 0.000
E10.5 With peripheral circulatory complications
0.694 0.306 0.000
Q74 Other congenital malformations of limb(s)
0.694 0.306 0.000
Q60.2 Renal agenesis, unspecified
0.692 0.308 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.691 0.309 0.000
B15-B19 Viral hepatitis
0.691 0.309 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.690 0.310 0.000
C31 Malignant neoplasm of accessory sinuses
0.690 0.310 0.000
C33 Malignant neoplasm of trachea
0.690 0.310 0.000
E27.5 Adrenomedullary hyperfunction
0.690 0.310 0.000
E27.0 Other adrenocortical overactivity
0.690 0.310 0.000
K31.4 Gastric diverticulum
0.689 0.311 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.689 0.311 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.689 0.311 0.000
N18.8 Other chronic renal failure
0.689 0.311 0.000
M05.8 Other seropositive rheumatoid arthritis
0.001 0.313 0.686
K31.2 Hourglass stricture and stenosis of stomach
0.687 0.313 0.000
K31.0 Acute dilatation of stomach
0.687 0.313 0.000
E28 Ovarian dysfunction
0.686 0.314 0.000
G70-G73 Diseases of myoneural junction and muscle
0.686 0.314 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.315 0.685
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.684 0.315 0.000
G56.1 Other lesions of median nerve
0.684 0.316 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.316 0.684
M06.38 Rheumatoid nodule (Other)
0.000 0.316 0.684
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.316 0.684
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.316 0.684
M06.33 Rheumatoid nodule (Forearm)
0.000 0.316 0.684
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.316 0.684
E21.5 Disorder of parathyroid gland, unspecified
0.684 0.316 0.000
K31.6 Fistula of stomach and duodenum
0.683 0.316 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.683 0.317 0.000
Q60.0 Renal agenesis, unilateral
0.683 0.317 0.000
I07.1 Tricuspid insufficiency
0.683 0.317 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.317 0.683
E11.8 With unspecified complications
0.683 0.317 0.000
L10 Pemphigus
0.682 0.318 0.000
L14 Bullous disorders in diseases classified elsewhere
0.682 0.318 0.000
I97.1 Other functional disturbances following cardiac surgery
0.682 0.318 0.000
G20 Parkinson's disease
0.681 0.319 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.681 0.319 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.678 0.322 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.322 0.678
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.322 0.678
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.322 0.678
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.322 0.678
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.322 0.678
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.322 0.678
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.322 0.677
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.677 0.323 0.000
K25.2 Acute with both haemorrhage and perforation
0.677 0.323 0.000
K25.1 Acute with perforation
0.677 0.323 0.000
Q43.3 Congenital malformations of intestinal fixation
0.677 0.323 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.676 0.324 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.676 0.324 0.000
C91.7 Other lymphoid leukaemia
0.676 0.324 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.676 0.324 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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