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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28613901
log Bayes Factor = 12.234
Chromosome 22   position 45,260,956  (GRCh37) Explore rs28613901 on Ensembl!
Variant rs28613901 is part of Cluster X0226

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
I05-I09 Chronic rheumatic heart diseases
0.996 0.004 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.990 0.010 0.000
Chapter II Neoplasms
0.984 0.016 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.982 0.018 0.000
I08 Multiple valve diseases
0.981 0.019 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.977 0.023 0.000
C79 Secondary malignant neoplasm of other sites
0.975 0.025 0.000
Chapter VIII Diseases of the ear and mastoid process
0.972 0.028 0.000
Chapter V Mental and behavioural disorders
0.970 0.030 0.000
I20 Angina pectoris
0.968 0.032 0.000
E11 Non-insulin-dependent diabetes mellitus
0.968 0.032 0.000
I20.0 Unstable angina
0.966 0.034 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.960 0.040 0.000
E10.4 With neurological complications
0.959 0.041 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.958 0.042 0.000
Chapter VI Diseases of the nervous system
0.954 0.046 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.954 0.046 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.951 0.049 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.950 0.050 0.000
H65-H75 Diseases of middle ear and mastoid
0.949 0.051 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.948 0.052 0.000
E20-E35 Disorders of other endocrine glands
0.947 0.053 0.000
E10.9 Without complications
0.947 0.053 0.000
F30-F39 Mood [affective] disorders
0.943 0.057 0.000
Chapter XXII Codes for special purposes
0.940 0.060 0.000
I25.1 Atherosclerotic heart disease
0.939 0.061 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.935 0.065 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.933 0.067 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.932 0.068 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.927 0.073 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.918 0.082 0.000
I07 Rheumatic tricuspid valve diseases
0.914 0.086 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.914 0.086 0.000
Y60.0 During surgical operation
0.912 0.088 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.911 0.089 0.000
E16 Other disorders of pancreatic internal secretion
0.910 0.090 0.000
E50-E64 Other nutritional deficiencies
0.909 0.091 0.000
H66 Suppurative and unspecified otitis media
0.908 0.092 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.907 0.093 0.000
T43.2 Other and unspecified antidepressants
0.905 0.095 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.904 0.096 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.901 0.099 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.898 0.102 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.897 0.103 0.000
E10.3 With ophthalmic complications
0.897 0.103 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.893 0.107 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.892 0.108 0.000
I72 Other aneurysm
0.886 0.114 0.000
L57.0 Actinic keratosis
0.886 0.114 0.000
Y48 Anaesthetics and therapeutic gases
0.879 0.121 0.000
F31 Bipolar affective disorder
0.877 0.123 0.000
E14 Unspecified diabetes mellitus
0.876 0.124 0.000
I24 Other acute ischaemic heart diseases
0.874 0.126 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.870 0.130 0.000
H66.9 Otitis media, unspecified
0.870 0.130 0.000
Y42.5 Other oestrogens and progestogens
0.865 0.135 0.000
E10.1 With ketoacidosis
0.864 0.136 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.862 0.138 0.000
C78.0 Secondary malignant neoplasm of lung
0.862 0.138 0.000
I07.1 Tricuspid insufficiency
0.856 0.144 0.000
E16.2 Hypoglycaemia, unspecified
0.856 0.144 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.854 0.146 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.853 0.147 0.000
C80 Malignant neoplasm without specification of site
0.851 0.149 0.000
I22 Subsequent myocardial infarction
0.851 0.149 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.850 0.150 0.000
C43 Malignant melanoma of skin
0.850 0.150 0.000
G90-G99 Other disorders of the nervous system
0.848 0.152 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.848 0.152 0.000
I25.4 Coronary artery aneurysm
0.843 0.157 0.000
I73 Other peripheral vascular diseases
0.843 0.157 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.843 0.157 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.843 0.157 0.000
I08.0 Disorders of both mitral and aortic valves
0.840 0.160 0.000
E10.2 With renal complications
0.839 0.161 0.000
G12 Spinal muscular atrophy and related syndromes
0.837 0.163 0.000
W00-W19 Falls
0.837 0.163 0.000
I10-I15 Hypertensive diseases
0.834 0.166 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.833 0.167 0.000
Chapter I Certain infectious and parasitic diseases
0.832 0.168 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.832 0.168 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.829 0.171 0.000
C78.7 Secondary malignant neoplasm of liver
0.829 0.171 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.828 0.172 0.000
E11.9 Without complications
0.827 0.173 0.000
E29 Testicular dysfunction
0.826 0.174 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.823 0.177 0.000
E11.2 With renal complications
0.819 0.180 0.000
E11.5 With peripheral circulatory complications
0.818 0.182 0.000
F33 Recurrent depressive disorder
0.816 0.184 0.000
E14.9 Without complications
0.814 0.186 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.809 0.191 0.000
S80-S89 Injuries to the knee and lower leg
0.809 0.191 0.000
E55 Vitamin D deficiency
0.809 0.191 0.000
E11.6 With other specified complications
0.804 0.196 0.000
W50-W64 Exposure to animate mechanical forces
0.803 0.197 0.000
E24 Cushing's syndrome
0.803 0.197 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.802 0.198 0.000
E10.5 With peripheral circulatory complications
0.802 0.198 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.800 0.200 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.800 0.200 0.000
Chapter X Diseases of the respiratory system
0.796 0.204 0.000
G12.2 Motor neuron disease
0.794 0.206 0.000
E10.0 With coma
0.794 0.206 0.000
V10-V19 Pedal cyclist injured in transport accident
0.794 0.206 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.793 0.207 0.000
I12 Hypertensive renal disease
0.792 0.208 0.000
I05 Rheumatic mitral valve diseases
0.792 0.208 0.000
I77 Other disorders of arteries and arterioles
0.785 0.214 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.784 0.216 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.784 0.216 0.000
S90-S99 Injuries to the ankle and foot
0.784 0.216 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.784 0.216 0.000
C45 Mesothelioma
0.783 0.217 0.000
S82 Fracture of lower leg, including ankle
0.782 0.218 0.000
F00 Dementia in Alzheimer's disease
0.779 0.221 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.779 0.221 0.000
E23 Hypofunction and other disorders of pituitary gland
0.776 0.224 0.000
I12.0 Hypertensive renal disease with renal failure
0.775 0.225 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.775 0.225 0.000
I21 Acute myocardial infarction
0.774 0.226 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.774 0.226 0.000
J60-J70 Lung diseases due to external agents
0.773 0.227 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.772 0.228 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.771 0.229 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.769 0.231 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.769 0.231 0.000
I74 Arterial embolism and thrombosis
0.768 0.232 0.000
X20-X29 Contact with venomous animals and plants
0.766 0.234 0.000
I72.0 Aneurysm of carotid artery
0.766 0.234 0.000
J69 Pneumonitis due to solids and liquids
0.765 0.235 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.761 0.239 0.000
H69 Other disorders of Eustachian tube
0.761 0.239 0.000
U80 Agent resistant to penicillin and related antibiotics
0.760 0.240 0.000
G70-G73 Diseases of myoneural junction and muscle
0.760 0.240 0.000
J69.0 Pneumonitis due to food and vomit
0.760 0.240 0.000
E11.4 With neurological complications
0.759 0.241 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.757 0.243 0.000
Y00-Y09 Assault
0.757 0.243 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.756 0.244 0.000
I73.9 Peripheral vascular disease, unspecified
0.755 0.245 0.000
Y48.4 Anaesthetic, unspecified
0.754 0.246 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.754 0.246 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.754 0.246 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.753 0.247 0.000
U51 Admission status on psychiatric patients
0.753 0.247 0.000
F39 Unspecified mood [affective] disorder
0.751 0.249 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.750 0.250 0.000
C43.9 Malignant melanoma of skin, unspecified
0.745 0.254 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.745 0.255 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.745 0.255 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.744 0.256 0.000
H90-H95 Other disorders of ear
0.744 0.256 0.000
L03 Cellulitis
0.744 0.256 0.000
I77.1 Stricture of artery
0.743 0.257 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.742 0.258 0.000
E29.1 Testicular hypofunction
0.740 0.260 0.000
Y48.3 Local anaesthetics
0.740 0.260 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.739 0.260 0.000
E55.9 Vitamin D deficiency, unspecified
0.737 0.263 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.737 0.263 0.000
V40-V49 Car occupant injured in transport accident
0.737 0.263 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.737 0.263 0.000
H74 Other disorders of middle ear and mastoid
0.735 0.265 0.000
E26 Hyperaldosteronism
0.734 0.266 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.266 0.000
H72 Perforation of tympanic membrane
0.734 0.266 0.000
L03.1 Cellulitis of other parts of limb
0.734 0.266 0.000
G95 Other diseases of spinal cord
0.734 0.266 0.000
S20-S29 Injuries to the thorax
0.733 0.267 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.731 0.269 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
H60-H62 Diseases of external ear
0.731 0.269 0.000
F30 Manic episode
0.731 0.269 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.730 0.269 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.730 0.270 0.000
F02 Dementia in other diseases classified elsewhere
0.730 0.270 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.730 0.270 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.727 0.273 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.727 0.273 0.000
G11 Hereditary ataxia
0.726 0.274 0.000
D80-D89 Certain disorders involving the immune mechanism
0.723 0.276 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.723 0.277 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.723 0.277 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.722 0.278 0.000
I26 Pulmonary embolism
0.720 0.280 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.719 0.280 0.000
I72.3 Aneurysm of iliac artery
0.718 0.281 0.000
E61 Deficiency of other nutrient elements
0.718 0.282 0.000
E11.8 With unspecified complications
0.718 0.282 0.000
Y52 Agents primarily affecting the cardiovascular system
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E34 Other endocrine disorders
0.716 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
F06.7 Mild cognitive disorder
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.284 0.000
X85-X99 Assault
0.715 0.284 0.000
X30-X39 Exposure to forces of nature
0.715 0.284 0.000
X10-X19 Contact with heat and hot substances
0.715 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.284 0.000
W75-W84 Other accidental threats to breathing
0.715 0.284 0.000
W65-W74 Accidental drowning and submersion
0.715 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.284 0.000
V95-V97 Air and space transport accidents
0.715 0.284 0.000
V90-V94 Water transport accidents
0.715 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.284 0.000
J09-J18 Influenza and pneumonia
0.715 0.285 0.000
I09 Other rheumatic heart diseases
0.714 0.286 0.000
I06 Rheumatic aortic valve diseases
0.714 0.286 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.713 0.287 0.000
H66.3 Other chronic suppurative otitis media
0.712 0.287 0.000
D86 Sarcoidosis
0.712 0.288 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.710 0.289 0.000
S82.4 Fracture of fibula alone
0.710 0.290 0.000
S82.1 Fracture of upper end of tibia
0.709 0.291 0.000
H71 Cholesteatoma of middle ear
0.709 0.291 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.708 0.292 0.000
E40-E46 Malnutrition
0.708 0.292 0.000
S90 Superficial injury of ankle and foot
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
I21.9 Acute myocardial infarction, unspecified
0.705 0.295 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.704 0.295 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.704 0.296 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.704 0.296 0.000
I72.4 Aneurysm of artery of lower extremity
0.704 0.296 0.000
I08.9 Multiple valve disease, unspecified
0.704 0.296 0.000
I08.8 Other multiple valve diseases
0.704 0.296 0.000
Y65 Other misadventures during surgical and medical care
0.702 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y58 Bacterial vaccines
0.701 0.299 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
D45 Polycythaemia vera
0.699 0.301 0.000
H73 Other disorders of tympanic membrane
0.698 0.302 0.000
E28 Ovarian dysfunction
0.697 0.303 0.000
F99-F99 Unspecified mental disorder
0.697 0.303 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.695 0.304 0.000
F70-F79 Mental retardation
0.695 0.304 0.000
G96 Other disorders of central nervous system
0.695 0.305 0.000
E11.7 With multiple complications
0.694 0.306 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.694 0.306 0.000
I27 Other pulmonary heart diseases
0.692 0.308 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.691 0.308 0.000
E13 Other specified diabetes mellitus
0.691 0.309 0.000
H70 Mastoiditis and related conditions
0.691 0.309 0.000
E23.2 Diabetes insipidus
0.690 0.310 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.690 0.310 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.690 0.310 0.000
F60-F69 Disorders of adult personality and behaviour
0.689 0.311 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.689 0.311 0.000
Y64 Contaminated medical or biological substances
0.688 0.311 0.000
Y63 Failure in dosage during surgical and medical care
0.688 0.311 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.688 0.311 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.688 0.311 0.000
Y69 Unspecified misadventure during surgical and medical care
0.688 0.311 0.000
Y66 Nonadministration of surgical and medical care
0.688 0.311 0.000
F31.9 Bipolar affective disorder, unspecified
0.688 0.312 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.688 0.312 0.000
X50-X57 Overexertion, travel and privation
0.687 0.313 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.686 0.314 0.000
F80-F89 Disorders of psychological development
0.685 0.315 0.000
E53 Deficiency of other B group vitamins
0.685 0.315 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.685 0.315 0.000
A00-A09 Intestinal infectious diseases
0.685 0.315 0.000
G90 Disorders of autonomic nervous system
0.684 0.316 0.000
I25.3 Aneurysm of heart
0.683 0.317 0.000
T33-T35 Frostbite
0.682 0.318 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.682 0.318 0.000
T00-T07 Injuries involving multiple body regions
0.682 0.318 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.681 0.319 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.319 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.681 0.319 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
T36 Poisoning by systemic antibiotics
0.681 0.319 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.681 0.319 0.000
H68 Eustachian salpingitis and obstruction
0.681 0.319 0.000
H67 Otitis media in diseases classified elsewhere
0.681 0.319 0.000
C79.2 Secondary malignant neoplasm of skin
0.681 0.319 0.000
I05.0 Mitral stenosis
0.681 0.319 0.000
D86.9 Sarcoidosis, unspecified
0.680 0.320 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.680 0.320 0.000
E15 Nondiabetic hypoglycaemic coma
0.679 0.320 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.680 0.320 0.000
C43.4 Malignant melanoma of scalp and neck
0.679 0.321 0.000
E11.3 With ophthalmic complications
0.679 0.321 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.679 0.321 0.000
E32 Diseases of thymus
0.679 0.321 0.000
E31 Polyglandular dysfunction
0.679 0.321 0.000
E30 Disorders of puberty, not elsewhere classified
0.679 0.321 0.000
E25 Adrenogenital disorders
0.679 0.321 0.000
E20 Hypoparathyroidism
0.679 0.321 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.678 0.322 0.000
Chapter XIV Diseases of the genitourinary system
0.677 0.323 0.000
Y46.6 Other and unspecified antiepileptics
0.677 0.323 0.000
F38 Other mood [affective] disorders
0.676 0.324 0.000
F34 Persistent mood [affective] disorders
0.676 0.324 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.676 0.324 0.000
C43.5 Malignant melanoma of trunk
0.676 0.324 0.000
E11.0 With coma
0.675 0.325 0.000
G83 Other paralytic syndromes
0.675 0.325 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.675 0.325 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.674 0.326 0.000
S70-S79 Injuries to the hip and thigh
0.673 0.327 0.000
N17-N19 Renal failure
0.670 0.330 0.000
E65-E68 Obesity and other hyperalimentation
0.670 0.330 0.000
U89 Agent resistant to other and unspecified antibiotics
0.669 0.331 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.669 0.331 0.000
C79.6 Secondary malignant neoplasm of ovary
0.668 0.331 0.000
B35-B49 Mycoses
0.668 0.332 0.000
Y60.9 During unspecified surgical and medical care
0.668 0.332 0.000
Y60.8 During other surgical and medical care
0.668 0.332 0.000
Y60.7 During administration of enema
0.668 0.332 0.000
Y60.6 During aspiration, puncture and other catheterisation
0.668 0.332 0.000
Y60.5 During heart catheterisation
0.668 0.332 0.000
Y60.4 During endoscopic examination
0.668 0.332 0.000
Y60.3 During injection or immunisation
0.668 0.332 0.000
Y60.2 During kidney dialysis or other perfusion
0.668 0.332 0.000
Y60.1 During infusion or transfusion
0.668 0.332 0.000
J81 Pulmonary oedema
0.667 0.333 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.667 0.333 0.000
W05 Fall involving wheelchair
0.665 0.334 0.000
I72.8 Aneurysm of other specified arteries
0.665 0.335 0.000
F03 Unspecified dementia
0.665 0.335 0.000
D46 Myelodysplastic syndromes
0.665 0.335 0.000
T43.9 Psychotropic drug, unspecified
0.665 0.335 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.665 0.335 0.000
T43.6 Psychostimulants with abuse potential
0.665 0.335 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.665 0.335 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.665 0.335 0.000
T45.5 Anticoagulants
0.665 0.335 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.664 0.336 0.000
S82.2 Fracture of shaft of tibia
0.664 0.336 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.662 0.338 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.661 0.339 0.000
A80-A89 Viral infections of the central nervous system
0.661 0.339 0.000
F32 Depressive episode
0.660 0.340 0.000
H65 Nonsuppurative otitis media
0.660 0.340 0.000
L50-L54 Urticaria and erythema
0.660 0.340 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.660 0.340 0.000
S82.40 Fracture of fibula alone (closed)
0.659 0.341 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.658 0.342 0.000
F09 Unspecified organic or symptomatic mental disorder
0.658 0.342 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.658 0.342 0.000
W18 Other fall on same level
0.658 0.342 0.000
B50-B64 Protozoal diseases
0.657 0.343 0.000
S82.10 Fracture of upper end of tibia (closed)
0.657 0.343 0.000
V80-V89 Other land transport accidents
0.657 0.343 0.000
X60-X84 Intentional self-harm
0.657 0.343 0.000
I07.9 Tricuspid valve disease, unspecified
0.656 0.344 0.000
I07.8 Other tricuspid valve diseases
0.656 0.344 0.000
I07.2 Tricuspid stenosis with insufficiency
0.656 0.344 0.000
I07.0 Tricuspid stenosis
0.656 0.344 0.000
N18 Chronic renal failure
0.655 0.345 0.000
L10-L14 Bullous disorders
0.655 0.345 0.000
E24.0 Pituitary-dependent Cushing's disease
0.654 0.346 0.000
Y42.9 Other and unspecified hormone antagonists
0.653 0.347 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.653 0.347 0.000
Y42.4 Oral contraceptives
0.653 0.347 0.000
Y42.2 Antithyroid drugs
0.653 0.347 0.000
Y42.1 Thyroid hormones and substitutes
0.653 0.347 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.653 0.347 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.653 0.347 0.000
E16.4 Abnormal secretion of gastrin
0.653 0.347 0.000
E16.3 Increased secretion of glucagon
0.653 0.347 0.000
E16.1 Other hypoglycaemia
0.653 0.347 0.000
L60-L75 Disorders of skin appendages
0.653 0.347 0.000
I21.4 Acute subendocardial myocardial infarction
0.652 0.348 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.652 0.348 0.000
E63 Other nutritional deficiencies
0.652 0.348 0.000
E56 Other vitamin deficiencies
0.652 0.348 0.000
E51 Thiamine deficiency
0.652 0.348 0.000
E50 Vitamin A deficiency
0.652 0.348 0.000
E60 Dietary zinc deficiency
0.652 0.348 0.000
E59 Dietary selenium deficiency
0.652 0.348 0.000
E58 Dietary calcium deficiency
0.652 0.348 0.000
E54 Ascorbic acid deficiency
0.652 0.348 0.000
E52 Niacin deficiency [pellagra]
0.652 0.348 0.000
H66.4 Suppurative otitis media, unspecified
0.651 0.349 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.651 0.349 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.651 0.349 0.000
H66.0 Acute suppurative otitis media
0.651 0.349 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.650 0.350 0.000
C46 Kaposi's sarcoma
0.650 0.350 0.000
E11.1 With ketoacidosis
0.650 0.350 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.650 0.350 0.000
T42.4 Benzodiazepines
0.648 0.351 0.000
I20.1 Angina pectoris with documented spasm
0.648 0.352 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.648 0.352 0.000
W51 Striking against or bumped into by another person
0.648 0.352 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.648 0.352 0.000
W19 Unspecified fall
0.648 0.352 0.000
I25.5 Ischaemic cardiomyopathy
0.647 0.353 0.000
Y46.2 Hydantoin derivatives
0.647 0.353 0.000
G81 Hemiplegia
0.646 0.354 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.646 0.354 0.000
L58 Radiodermatitis
0.646 0.354 0.000
L55 Sunburn
0.646 0.354 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.645 0.355 0.000
E24.9 Cushing's syndrome, unspecified
0.645 0.355 0.000
U51.1 Previously admitted to a psychiatric hospital of the provider
0.644 0.356 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.643 0.356 0.000
G14 Postpolio syndrome
0.643 0.356 0.000
G10 Huntington's disease
0.643 0.356 0.000
I22.8 Subsequent myocardial infarction of other sites
0.642 0.358 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.641 0.359 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.641 0.359 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.641 0.359 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.640 0.360 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.640 0.360 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.640 0.360 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.640 0.360 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.640 0.360 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.640 0.360 0.000
Y51.0 Anticholinesterase agents
0.640 0.360 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.639 0.361 0.000
L57.5 Actinic granuloma
0.639 0.361 0.000
L57.4 Cutis laxa senilis
0.639 0.361 0.000
L57.3 Poikiloderma of Civatte
0.639 0.361 0.000
L57.2 Cutis rhomboidalis nuchae
0.639 0.361 0.000
L57.1 Actinic reticuloid
0.639 0.361 0.000
S32 Fracture of lumbar spine and pelvis
0.639 0.361 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.638 0.362 0.000
U80.0 Penicillin resistant agent
0.638 0.362 0.000
C45.0 Mesothelioma of pleura
0.637 0.363 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.637 0.363 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.637 0.363 0.000
C44 Other malignant neoplasms of skin
0.636 0.364 0.000
G30-G32 Other degenerative diseases of the nervous system
0.636 0.364 0.000
F20 Schizophrenia
0.636 0.364 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.636 0.364 0.000
I72.9 Aneurysm of unspecified site
0.635 0.365 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.635 0.365 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.635 0.365 0.000
I72.2 Aneurysm of renal artery
0.635 0.365 0.000
I72.1 Aneurysm of artery of upper extremity
0.635 0.365 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.633 0.367 0.000
N25-N29 Other disorders of kidney and ureter
0.632 0.368 0.000
Y45.2 Propionic acid derivatives
0.632 0.368 0.000
W07 Fall involving chair
0.631 0.369 0.000
A08 Viral and other specified intestinal infections
0.631 0.369 0.000
H80-H83 Diseases of inner ear
0.631 0.369 0.000
Y48.5 Therapeutic gases
0.630 0.369 0.000
Y48.2 Other and unspecified general anaesthetics
0.630 0.369 0.000
Y48.1 Parenteral anaesthetics
0.630 0.369 0.000
Y48.0 Inhaled anaesthetics
0.630 0.369 0.000
F31.8 Other bipolar affective disorders
0.629 0.371 0.000
F31.7 Bipolar affective disorder, currently in remission
0.629 0.371 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.629 0.371 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.629 0.371 0.000
E14.8 With unspecified complications
0.628 0.371 0.000
E14.7 With multiple complications
0.628 0.371 0.000
E14.6 With other specified complications
0.628 0.371 0.000
E14.5 With peripheral circulatory complications
0.628 0.371 0.000
E14.4 With neurological complications
0.628 0.371 0.000
E14.2 Withrenal complications
0.628 0.371 0.000
E14.1 With ketoacidosis
0.628 0.371 0.000
E14.0 With coma
0.628 0.371 0.000
W06 Fall involving bed
0.628 0.372 0.000
J14 Pneumonia due to Haemophilus influenzae
0.628 0.372 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.627 0.372 0.000
N19 Unspecified renal failure
0.627 0.373 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.627 0.373 0.000
I24.1 Dressler's syndrome
0.627 0.373 0.000
H69.9 Eustachian tube disorder, unspecified
0.626 0.374 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.626 0.374 0.000
C50-C50 Malignant neoplasm of breast
0.625 0.374 0.000
G63.2 Diabetic polyneuropathy
0.625 0.375 0.000
I70 Atherosclerosis
0.625 0.375 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.625 0.375 0.000
S10-S19 Injuries to the neck
0.624 0.376 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.624 0.376 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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