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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17094474
log Bayes Factor = 8.18878
Chromosome 14   position 58,819,463  (GRCh37) Explore rs17094474 on Ensembl!
Variant rs17094474 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
I10-I15 Hypertensive diseases
0.994 0.006 0.000
E10-E14 Diabetes mellitus
0.994 0.006 0.000
I20 Angina pectoris
0.993 0.007 0.000
B95-B98 Bacterial, viral and other infectious agents
0.987 0.013 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.986 0.014 0.000
I10 Essential (primary) hypertension
0.985 0.015 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.980 0.020 0.000
I25 Chronic ischaemic heart disease
0.976 0.024 0.000
I20.0 Unstable angina
0.975 0.025 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.973 0.027 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.972 0.028 0.000
M15-M19 Arthrosis
0.969 0.031 0.000
M19 Other arthrosis
0.966 0.034 0.000
E10 Insulin-dependent diabetes mellitus
0.965 0.035 0.000
M19.9 Arthrosis, unspecified
0.963 0.037 0.000
M45-M49 Spondylopathies
0.963 0.037 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.957 0.043 0.000
I20.9 Angina pectoris, unspecified
0.954 0.046 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.950 0.050 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.950 0.050 0.000
M48 Other spondylopathies
0.948 0.052 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.944 0.056 0.000
E11 Non-insulin-dependent diabetes mellitus
0.943 0.057 0.000
B35-B49 Mycoses
0.942 0.058 0.000
Chapter VIII Diseases of the ear and mastoid process
0.942 0.058 0.000
I05-I09 Chronic rheumatic heart diseases
0.940 0.060 0.000
M48.0 Spinal stenosis
0.938 0.062 0.000
S90-S99 Injuries to the ankle and foot
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.925 0.075 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.924 0.076 0.000
M19.94 Arthrosis, unspecified (Hand)
0.920 0.080 0.000
E83 Disorders of mineral metabolism
0.919 0.081 0.000
A30-A49 Other bacterial diseases
0.915 0.085 0.000
Chapter XX External causes of morbidity and mortality
0.911 0.089 0.000
I24 Other acute ischaemic heart diseases
0.909 0.091 0.000
E88 Other metabolic disorders
0.902 0.098 0.000
M48.06 Spinal stenosis (Lumbar region)
0.899 0.101 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.896 0.104 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.892 0.108 0.000
T91 Sequelae of injuries of neck and trunk
0.892 0.108 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.878 0.122 0.000
M48.02 Spinal stenosis (Cervical region)
0.871 0.129 0.000
E78.5 Hyperlipidaemia, unspecified
0.870 0.130 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.867 0.133 0.000
I08 Multiple valve diseases
0.866 0.134 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.864 0.136 0.000
M19.98 Arthrosis, unspecified (Other)
0.863 0.137 0.000
Chapter XXII Codes for special purposes
0.860 0.140 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.860 0.140 0.000
M80-M85 Disorders of bone density and structure
0.860 0.140 0.000
Chapter VI Diseases of the nervous system
0.858 0.142 0.000
T92 Sequelae of injuries of upper limb
0.857 0.143 0.000
S92 Fracture of foot, except ankle
0.857 0.143 0.000
I22 Subsequent myocardial infarction
0.853 0.147 0.000
A41 Other septicaemia
0.852 0.148 0.000
E10.1 With ketoacidosis
0.851 0.149 0.000
H60-H62 Diseases of external ear
0.851 0.149 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.848 0.152 0.000
E10.8 With unspecified complications
0.843 0.157 0.000
B37 Candidiasis
0.839 0.161 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.835 0.165 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.833 0.167 0.000
D55-D59 Haemolytic anaemias
0.832 0.168 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.830 0.170 0.000
Q60-Q64 Congenital malformations of the urinary system
0.827 0.173 0.000
I05 Rheumatic mitral valve diseases
0.822 0.178 0.000
E11.2 With renal complications
0.819 0.181 0.000
E14 Unspecified diabetes mellitus
0.818 0.182 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.814 0.186 0.000
I11 Hypertensive heart disease
0.814 0.186 0.000
M45 Ankylosing spondylitis
0.813 0.187 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.810 0.190 0.000
E11.0 With coma
0.810 0.190 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.807 0.193 0.000
E85 Amyloidosis
0.804 0.196 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.803 0.197 0.000
E83.4 Disorders of magnesium metabolism
0.802 0.198 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.800 0.200 0.000
E11.3 With ophthalmic complications
0.799 0.201 0.000
S60-S69 Injuries to the wrist and hand
0.797 0.203 0.000
M80 Osteoporosis with pathological fracture
0.796 0.204 0.000
E10.3 With ophthalmic complications
0.795 0.205 0.000
B35 Dermatophytosis
0.795 0.205 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.794 0.206 0.000
E86 Volume depletion
0.793 0.207 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.792 0.208 0.000
H80-H83 Diseases of inner ear
0.791 0.209 0.000
D68 Other coagulation defects
0.791 0.209 0.000
I25.3 Aneurysm of heart
0.790 0.210 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.783 0.217 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.782 0.218 0.000
S92.0 Fracture of calcaneus
0.782 0.218 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.781 0.219 0.000
S50-S59 Injuries to the elbow and forearm
0.780 0.220 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.779 0.221 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.779 0.221 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.777 0.222 0.000
I24.8 Other forms of acute ischaemic heart disease
0.777 0.223 0.000
D80-D89 Certain disorders involving the immune mechanism
0.776 0.223 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.775 0.225 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.775 0.225 0.000
E40-E46 Malnutrition
0.775 0.225 0.000
M19.1 Posttraumatic arthrosis of other joints
0.775 0.225 0.000
T91.1 Sequelae of fracture of spine
0.773 0.227 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.770 0.230 0.000
E11.1 With ketoacidosis
0.769 0.231 0.000
I30-I52 Other forms of heart disease
0.769 0.231 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
I12 Hypertensive renal disease
0.767 0.233 0.000
S91 Open wound of ankle and foot
0.766 0.234 0.000
G90-G99 Other disorders of the nervous system
0.766 0.234 0.000
H90-H95 Other disorders of ear
0.766 0.234 0.000
E83.5 Disorders of calcium metabolism
0.765 0.235 0.000
T91.3 Sequelae of injury of spinal cord
0.764 0.236 0.000
S32 Fracture of lumbar spine and pelvis
0.762 0.238 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.758 0.242 0.000
B44 Aspergillosis
0.756 0.244 0.000
E50-E64 Other nutritional deficiencies
0.756 0.244 0.000
Y52 Agents primarily affecting the cardiovascular system
0.756 0.244 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.753 0.247 0.000
S10-S19 Injuries to the neck
0.752 0.248 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.751 0.249 0.000
M16 Coxarthrosis [arthrosis of hip]
0.749 0.251 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.749 0.251 0.000
H61 Other disorders of external ear
0.749 0.251 0.000
S92.5 Fracture of other toe
0.748 0.252 0.000
B65-B83 Helminthiases
0.748 0.252 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.747 0.253 0.000
E78.8 Other disorders of lipoprotein metabolism
0.745 0.255 0.000
E10.9 Without complications
0.744 0.256 0.000
E74 Other disorders of carbohydrate metabolism
0.742 0.257 0.000
T21 Burn and corrosion of trunk
0.740 0.260 0.000
B15-B19 Viral hepatitis
0.738 0.262 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.737 0.263 0.000
D75 Other diseases of blood and blood-forming organs
0.736 0.264 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.736 0.264 0.000
M19.0 Primary arthrosis of other joints
0.734 0.266 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.733 0.267 0.000
M16.1 Other primary coxarthrosis
0.731 0.269 0.000
M60-M63 Disorders of muscles
0.731 0.269 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.731 0.269 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.731 0.269 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.730 0.270 0.000
B99-B99 Other infectious diseases
0.730 0.270 0.000
Q80-Q89 Other congenital malformations
0.729 0.271 0.000
I08.0 Disorders of both mitral and aortic valves
0.728 0.272 0.000
E73 Lactose intolerance
0.728 0.272 0.000
S92.00 Fracture of calcaneus (closed)
0.728 0.272 0.000
D73 Diseases of spleen
0.728 0.272 0.000
S80-S89 Injuries to the knee and lower leg
0.727 0.273 0.000
M46 Other inflammatory spondylopathies
0.727 0.273 0.000
E10.2 With renal complications
0.727 0.273 0.000
M91-M94 Chondropathies
0.726 0.274 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
E10.5 With peripheral circulatory complications
0.724 0.276 0.000
M40-M43 Deforming dorsopathies
0.721 0.279 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.721 0.279 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.720 0.280 0.000
E11.9 Without complications
0.719 0.281 0.000
I25.1 Atherosclerotic heart disease
0.719 0.281 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.719 0.281 0.000
T43.2 Other and unspecified antidepressants
0.718 0.282 0.000
A46 Erysipelas
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I05.9 Mitral valve disease, unspecified
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.716 0.284 0.000
Q61 Cystic kidney disease
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.714 0.286 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
I15 Secondary hypertension
0.712 0.287 0.000
I13 Hypertensive heart and renal disease
0.712 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
B37.1 Pulmonary candidiasis
0.712 0.288 0.000
Y57 Other and unspecified drugs and medicaments
0.711 0.288 0.000
G56 Mononeuropathies of upper limb
0.711 0.289 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.709 0.291 0.000
B37.9 Candidiasis, unspecified
0.708 0.292 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.707 0.293 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.707 0.293 0.000
E78.2 Mixed hyperlipidaemia
0.705 0.295 0.000
S68 Traumatic amputation of wrist and hand
0.705 0.295 0.000
E87.2 Acidosis
0.703 0.297 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.703 0.297 0.000
I45 Other conduction disorders
0.703 0.297 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.702 0.297 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.702 0.297 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.702 0.297 0.000
E83.1 Disorders of iron metabolism
0.702 0.298 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.702 0.298 0.000
I50 Heart failure
0.702 0.298 0.000
D59 Acquired haemolytic anaemia
0.702 0.298 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.701 0.299 0.000
A40 Streptococcal septicaemia
0.700 0.300 0.000
I25.6 Silent myocardial ischaemia
0.700 0.300 0.000
I25.4 Coronary artery aneurysm
0.700 0.300 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.700 0.300 0.000
B37.0 Candidal stomatitis
0.700 0.300 0.000
H60 Otitis externa
0.696 0.304 0.000
V20-V29 Motorcycle rider injured in transport accident
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
D72 Other disorders of white blood cells
0.695 0.305 0.000
M15 Polyarthrosis
0.695 0.305 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.694 0.306 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.693 0.306 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.693 0.307 0.000
M19.8 Other specified arthrosis
0.693 0.307 0.000
M19.2 Other secondary arthrosis
0.693 0.307 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.693 0.307 0.000
E10.7 With multiple complications
0.692 0.308 0.000
E10.6 With other specified complications
0.692 0.308 0.000
E10.0 With coma
0.692 0.308 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.691 0.309 0.000
M49 Spondylopathies in diseases classified elsewhere
0.690 0.310 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.690 0.310 0.000
E65-E68 Obesity and other hyperalimentation
0.690 0.310 0.000
E10.4 With neurological complications
0.689 0.311 0.000
B25-B34 Other viral diseases
0.688 0.312 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.688 0.312 0.000
I50.9 Heart failure, unspecified
0.688 0.312 0.000
A41.8 Other specified septicaemia
0.687 0.313 0.000
M00-M03 Infectious arthropathies
0.687 0.313 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.687 0.313 0.000
S62 Fracture at wrist and hand level
0.687 0.313 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.687 0.313 0.000
D68.2 Hereditary deficiency of other clotting factors
0.687 0.313 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.686 0.314 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.314 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.686 0.314 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.686 0.314 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.686 0.314 0.000
T36 Poisoning by systemic antibiotics
0.686 0.314 0.000
A00-A09 Intestinal infectious diseases
0.686 0.314 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.684 0.316 0.000
G93 Other disorders of brain
0.684 0.316 0.000
I21 Acute myocardial infarction
0.684 0.316 0.000
B35.3 Tinea pedis
0.684 0.316 0.000
T98 Sequelae of other and unspecified effects of external causes
0.683 0.317 0.000
X50-X57 Overexertion, travel and privation
0.681 0.319 0.000
T95 Sequelae of burns, corrosions and frostbite
0.681 0.319 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.681 0.319 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.681 0.319 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.681 0.319 0.000
M48.9 Spondylopathy, unspecified
0.680 0.320 0.000
M48.8 Other specified spondylopathies
0.680 0.320 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.680 0.320 0.000
M48.4 Fatigue fracture of vertebra
0.680 0.320 0.000
M48.3 Traumatic spondylopathy
0.680 0.320 0.000
M48.2 Kissing spine
0.680 0.320 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.680 0.320 0.000
D60-D64 Aplastic and other anaemias
0.679 0.321 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.678 0.322 0.000
E83.3 Disorders of phosphorus metabolism
0.677 0.323 0.000
E11.8 With unspecified complications
0.676 0.324 0.000
E11.7 With multiple complications
0.676 0.324 0.000
B48 Other mycoses, not elsewhere classified
0.676 0.324 0.000
B47 Mycetoma
0.676 0.324 0.000
B46 Zygomycosis
0.676 0.324 0.000
B45 Cryptococcosis
0.676 0.324 0.000
B43 Chromomycosis and phaeomycotic abscess
0.676 0.324 0.000
B42 Sporotrichosis
0.676 0.324 0.000
B41 Paracoccidioidomycosis
0.676 0.324 0.000
B40 Blastomycosis
0.676 0.324 0.000
B39 Histoplasmosis
0.676 0.324 0.000
B38 Coccidioidomycosis
0.676 0.324 0.000
B36 Other superficial mycoses
0.676 0.324 0.000
B49 Unspecified mycosis
0.676 0.324 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.675 0.325 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.675 0.325 0.000
I09 Other rheumatic heart diseases
0.674 0.326 0.000
I06 Rheumatic aortic valve diseases
0.674 0.326 0.000
H90 Conductive and sensorineural hearing loss
0.674 0.326 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.673 0.327 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.673 0.327 0.000
M48.04 Spinal stenosis (Thoracic region)
0.673 0.327 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.673 0.327 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.673 0.327 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.673 0.327 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.672 0.328 0.000
W00-W19 Falls
0.671 0.329 0.000
V40-V49 Car occupant injured in transport accident
0.671 0.329 0.000
S92.50 Fracture of other toe (closed)
0.671 0.329 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.669 0.331 0.000
E14.9 Without complications
0.668 0.332 0.000
I74 Arterial embolism and thrombosis
0.668 0.332 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.667 0.332 0.000
S98 Traumatic amputation of ankle and foot
0.666 0.334 0.000
S97 Crushing injury of ankle and foot
0.666 0.334 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.666 0.334 0.000
S95 Injury of blood vessels at ankle and foot level
0.666 0.334 0.000
S94 Injury of nerves at ankle and foot level
0.666 0.334 0.000
V80-V89 Other land transport accidents
0.666 0.334 0.000
T23 Burn and corrosion of wrist and hand
0.665 0.335 0.000
G56.2 Lesion of ulnar nerve
0.665 0.335 0.000
D86 Sarcoidosis
0.664 0.336 0.000
D68.9 Coagulation defect, unspecified
0.664 0.336 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.663 0.337 0.000
Q35-Q37 Cleft lip and cleft palate
0.663 0.337 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.663 0.337 0.000
E78.6 Lipoprotein deficiency
0.663 0.337 0.000
E78.4 Other hyperlipidaemia
0.663 0.337 0.000
E78.3 Hyperchylomicronaemia
0.663 0.337 0.000
E78.1 Pure hyperglyceridaemia
0.663 0.337 0.000
I22.8 Subsequent myocardial infarction of other sites
0.661 0.339 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.661 0.339 0.000
I20.8 Other forms of angina pectoris
0.659 0.341 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.659 0.341 0.000
E83.8 Other disorders of mineral metabolism
0.659 0.341 0.000
E83.2 Disorders of zinc metabolism
0.659 0.341 0.000
E83.0 Disorders of copper metabolism
0.659 0.341 0.000
E11.5 With peripheral circulatory complications
0.658 0.342 0.000
E11.6 With other specified complications
0.658 0.342 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.657 0.342 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.656 0.344 0.000
W50-W64 Exposure to animate mechanical forces
0.656 0.344 0.000
A48 Other bacterial diseases, not elsewhere classified
0.656 0.344 0.000
A44 Bartonellosis
0.656 0.344 0.000
A43 Nocardiosis
0.656 0.344 0.000
A42 Actinomycosis
0.656 0.344 0.000
A39 Meningococcal infection
0.656 0.344 0.000
A37 Whooping cough
0.656 0.344 0.000
A36 Diphtheria
0.656 0.344 0.000
A32 Listeriosis
0.656 0.344 0.000
A31 Infection due to other mycobacteria
0.656 0.344 0.000
A30 Leprosy [Hansen's disease]
0.656 0.344 0.000
A38 Scarlet fever
0.656 0.344 0.000
A35 Other tetanus
0.656 0.344 0.000
A34 Obstetrical tetanus
0.656 0.344 0.000
A33 Tetanus neonatorum
0.656 0.344 0.000
Q50-Q56 Congenital malformations of genital organs
0.655 0.345 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.654 0.346 0.000
X20-X29 Contact with venomous animals and plants
0.654 0.346 0.000
A80-A89 Viral infections of the central nervous system
0.654 0.346 0.000
T39.1 4-Aminophenol derivatives
0.654 0.346 0.000
Y35-Y36 Legal intervention and operations of war
0.653 0.347 0.000
Y10-Y34 Event of undetermined intent
0.653 0.347 0.000
Y00-Y09 Assault
0.653 0.347 0.000
X85-X99 Assault
0.653 0.347 0.000
X30-X39 Exposure to forces of nature
0.653 0.347 0.000
X00-X09 Exposure to smoke, fire and flames
0.653 0.347 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.653 0.347 0.000
W75-W84 Other accidental threats to breathing
0.653 0.347 0.000
W65-W74 Accidental drowning and submersion
0.653 0.347 0.000
V98-V99 Other and unspecified transport accidents
0.653 0.347 0.000
V95-V97 Air and space transport accidents
0.653 0.347 0.000
V90-V94 Water transport accidents
0.653 0.347 0.000
V70-V79 Bus occupant injured in transport accident
0.653 0.347 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.653 0.347 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.653 0.347 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.653 0.347 0.000
V01-V09 Pedestrian injured in transport accident
0.653 0.347 0.000
S99 Other and unspecified injuries of ankle and foot
0.653 0.347 0.000
I24.1 Dressler's syndrome
0.651 0.348 0.000
I72 Other aneurysm
0.651 0.349 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.651 0.349 0.000
H81 Disorders of vestibular function
0.651 0.349 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.651 0.349 0.000
S91.3 Open wound of other parts of foot
0.650 0.350 0.000
G03 Meningitis due to other and unspecified causes
0.650 0.350 0.000
D50-D53 Nutritional anaemias
0.650 0.350 0.000
D58 Other hereditary haemolytic anaemias
0.649 0.351 0.000
H80 Otosclerosis
0.649 0.351 0.000
S50 Superficial injury of forearm
0.648 0.352 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.648 0.352 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.648 0.352 0.000
T31 Burns classified according to extent of body surface involved
0.648 0.352 0.000
H61.1 Non-infective disorders of pinna
0.647 0.353 0.000
E88.9 Metabolic disorder, unspecified
0.646 0.353 0.000
E88.8 Other specified metabolic disorders
0.646 0.353 0.000
E88.3 Tumour lysis syndrome
0.646 0.353 0.000
E88.2 Lipomatosis, not elsewhere classified
0.646 0.353 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.646 0.353 0.000
S86 Injury of muscle and tendon at lower leg level
0.645 0.355 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.644 0.356 0.000
E85.9 Amyloidosis, unspecified
0.644 0.356 0.000
I45.1 Other and unspecified right bundle-branch block
0.641 0.359 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.640 0.360 0.000
S37 Injury of urinary and pelvic organs
0.640 0.360 0.000
S36 Injury of intra-abdominal organs
0.640 0.360 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.640 0.360 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.640 0.360 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.640 0.360 0.000
S31 Open wound of abdomen, lower back and pelvis
0.640 0.360 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.640 0.360 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.640 0.360 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.640 0.360 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.640 0.360 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.640 0.360 0.000
X60-X84 Intentional self-harm
0.638 0.362 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.637 0.363 0.000
S51 Open wound of forearm
0.637 0.363 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.637 0.363 0.000
Q63 Other congenital malformations of kidney
0.637 0.363 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.637 0.363 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.637 0.363 0.000
I05.1 Rheumatic mitral insufficiency
0.636 0.364 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.636 0.364 0.000
I30 Acute pericarditis
0.635 0.365 0.000
S90 Superficial injury of ankle and foot
0.634 0.365 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.634 0.366 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.633 0.367 0.000
I25.5 Ischaemic cardiomyopathy
0.633 0.367 0.000
E87.5 Hyperkalaemia
0.633 0.367 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.633 0.367 0.000
T39.0 Salicylates
0.630 0.370 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.630 0.370 0.000
D74 Methaemoglobinaemia
0.630 0.370 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.630 0.370 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.630 0.370 0.000
T90 Sequelae of injuries of head
0.628 0.372 0.000
Q00-Q07 Congenital malformations of the nervous system
0.626 0.374 0.000
I78 Diseases of capillaries
0.626 0.374 0.000
G95 Other diseases of spinal cord
0.624 0.375 0.000
M82 Osteoporosis in diseases classified elsewhere
0.624 0.376 0.000
S60 Superficial injury of wrist and hand
0.624 0.376 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.624 0.376 0.000
E14.3 With ophthalmic complications
0.623 0.377 0.000
B44.1 Other pulmonary aspergillosis
0.622 0.378 0.000
T21.0 Burn of unspecified degree of trunk
0.622 0.378 0.000
Y59 Other and unspecified vaccines and biological substances
0.621 0.379 0.000
Y58 Bacterial vaccines
0.621 0.379 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.621 0.379 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.621 0.379 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.621 0.379 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.621 0.379 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.621 0.379 0.000
Y48 Anaesthetics and therapeutic gases
0.621 0.379 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.621 0.379 0.000
G30-G32 Other degenerative diseases of the nervous system
0.621 0.379 0.000
I08.9 Multiple valve disease, unspecified
0.621 0.379 0.000
U80 Agent resistant to penicillin and related antibiotics
0.620 0.379 0.000
S92.2 Fracture of other tarsal bone(s)
0.620 0.380 0.000
H65-H75 Diseases of middle ear and mastoid
0.620 0.380 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.619 0.380 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.619 0.380 0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.619 0.380 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.619 0.380 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.619 0.380 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.619 0.380 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.619 0.380 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.619 0.381 0.000
H91 Other hearing loss
0.618 0.382 0.000
T25 Burn and corrosion of ankle and foot
0.617 0.383 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.617 0.383 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.617 0.383 0.000
T20 Burn and corrosion of head and neck
0.617 0.383 0.000
M83 Adult osteomalacia
0.617 0.383 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.616 0.383 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.616 0.384 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.616 0.384 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.615 0.385 0.000
E13 Other specified diabetes mellitus
0.615 0.385 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.615 0.385 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.615 0.385 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.615 0.385 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.615 0.385 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.615 0.385 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.615 0.385 0.000
T92.0 Sequelae of open wound of upper limb
0.615 0.385 0.000
S92.9 Fracture of foot, unspecified
0.615 0.385 0.000
S92.7 Multiple fractures of foot
0.615 0.385 0.000
S92.4 Fracture of great toe
0.615 0.385 0.000
S92.1 Fracture of talus
0.615 0.385 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.614 0.386 0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.614 0.386 0.000
D70 Agranulocytosis
0.614 0.386 0.000
E46 Unspecified protein-energy malnutrition
0.614 0.386 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.613 0.387 0.000
S32.1 Fracture of sacrum
0.613 0.387 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.613 0.387 0.000
I12.0 Hypertensive renal disease with renal failure
0.613 0.387 0.000
E85.4 Organ-limited amyloidosis
0.611 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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