TreeWAS – Variant ID: rs76637322

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
I20 Angina pectoris	0.996	0.004
I25.9 Chronic ischaemic heart disease, unspecified	0.995	0.005
Chapter VI Diseases of the nervous system	0.992	0.008
I30-I52 Other forms of heart disease	0.991	0.009
Chapter IV Endocrine, nutritional and metabolic diseases	0.991	0.009
E70-E90 Metabolic disorders	0.990	0.010
Chapter VIII Diseases of the ear and mastoid process	0.986	0.014
E87 Other disorders of fluid, electrolyte and acid-base balance	0.986	0.014
I25.1 Atherosclerotic heart disease	0.985	0.015
I24 Other acute ischaemic heart diseases	0.984	0.016
I51 Complications and ill-defined descriptions of heart disease	0.980	0.020
E87.6 Hypokalaemia	0.979	0.021
I20.9 Angina pectoris, unspecified	0.977	0.023
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.976	0.024
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.976	0.024
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.976	0.024
I50 Heart failure	0.974	0.026
I24.8 Other forms of acute ischaemic heart disease	0.969	0.031
O60-O75 Complications of labour and delivery	0.963	0.037
O20-O29 Other maternal disorders predominantly related to pregnancy	0.958	0.042
G90-G99 Other disorders of the nervous system	0.951	0.049
G50-G59 Nerve, nerve root and plexus disorders	0.950	0.050
I51.7 Cardiomegaly	0.949	0.051
I50.1 Left ventricular failure	0.949	0.051
S00-S09 Injuries to the head	0.948	0.052
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.938	0.062
I20.8 Other forms of angina pectoris	0.937	0.063
E83 Disorders of mineral metabolism	0.937	0.063
I05-I09 Chronic rheumatic heart diseases	0.935	0.065
S00 Superficial injury of head	0.918	0.082
O00-O08 Pregnancy with abortive outcome	0.914	0.086
H60-H62 Diseases of external ear	0.914	0.086
I20.1 Angina pectoris with documented spasm	0.914	0.086
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.909	0.091
G40-G47 Episodic and paroxysmal disorders	0.908	0.092
H90-H95 Other disorders of ear	0.904	0.096
E87.0 Hyperosmolality and hypernatraemia	0.895	0.105
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.894	0.106
O42 Premature rupture of membranes	0.893	0.107
S00.8 Superficial injury of other parts of head	0.892	0.108
E87.1 Hypo-osmolality and hyponatraemia	0.892	0.108
O26 Maternal care for other conditions predominantly related to pregnancy	0.886	0.114
E83.4 Disorders of magnesium metabolism	0.879	0.121
E89.0 Postprocedural hypothyroidism	0.878	0.122
O85-O92 Complications predominantly related to the puerperium	0.876	0.124
G95 Other diseases of spinal cord	0.875	0.125
O36 Maternal care for other known or suspected foetal problems	0.870	0.130
G45 Transient cerebral ischaemic attacks and related syndromes	0.869	0.131
I51.8 Other ill-defined heart diseases	0.867	0.133
I08 Multiple valve diseases	0.867	0.133
H61 Other disorders of external ear	0.866	0.134
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.866	0.134
I25.2 Old myocardial infarction	0.863	0.137
Q38-Q45 Other congenital malformations of the digestive system	0.860	0.140
S70-S79 Injuries to the hip and thigh	0.860	0.140
I25.8 Other forms of chronic ischaemic heart disease	0.859	0.141
I60-I69 Cerebrovascular diseases	0.856	0.144
O68 Labour and delivery complicated by foetal stress [distress]	0.855	0.145
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.855	0.145
S90-S99 Injuries to the ankle and foot	0.853	0.147
I50.0 Congestive heart failure	0.850	0.150
O62 Abnormalities of forces of labour	0.847	0.153
I95-I99 Other and unspecified disorders of the circulatory system	0.845	0.155
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.844	0.156
H65-H75 Diseases of middle ear and mastoid	0.842	0.158
Chapter V Mental and behavioural disorders	0.840	0.160
S80-S89 Injuries to the knee and lower leg	0.830	0.170
G00-G09 Inflammatory diseases of the central nervous system	0.826	0.174
O48 Prolonged pregnancy	0.824	0.176
O20 Haemorrhage in early pregnancy	0.823	0.177
G55.3 Nerve root and plexus compressions in other dorsopathies	0.820	0.180
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.820	0.180
O03 Spontaneous abortion	0.819	0.181
O35 Maternal care for known or suspected foetal abnormality and damage	0.817	0.183
I34 Nonrheumatic mitral valve disorders	0.816	0.184
O69 Labour and delivery complicated by umbilical cord complications	0.812	0.188
S32 Fracture of lumbar spine and pelvis	0.810	0.190
H91 Other hearing loss	0.810	0.190
G40 Epilepsy	0.808	0.192
G91 Hydrocephalus	0.804	0.196
I08.0 Disorders of both mitral and aortic valves	0.798	0.202
Q00-Q07 Congenital malformations of the nervous system	0.795	0.205
S05 Injury of eye and orbit	0.794	0.206
O42.9 Premature rupture of membranes, unspecified	0.794	0.206
G56 Mononeuropathies of upper limb	0.793	0.207
S01 Open wound of head	0.793	0.207
O64 Obstructed labour due to malposition and malpresentation of foetus	0.791	0.209
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.789	0.211
O02 Other abnormal products of conception	0.789	0.211
S70 Superficial injury of hip and thigh	0.787	0.213
Q60-Q64 Congenital malformations of the urinary system	0.787	0.213
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.784	0.216
G93 Other disorders of brain	0.784	0.216
I47 Paroxysmal tachycardia	0.782	0.218
O80-O84 Delivery	0.781	0.218
I51.4 Myocarditis, unspecified	0.780	0.220
I63 Cerebral infarction	0.779	0.221
I38 Endocarditis, valve unspecified	0.777	0.223
D50-D53 Nutritional anaemias	0.777	0.223
I25.0 Atherosclerotic cardiovascular disease, so described	0.776	0.224
H93 Other disorders of ear, not elsewhere classified	0.776	0.224
O75 Other complications of labour and delivery, not elsewhere classified	0.776	0.224
O36.5 Maternal care for poor foetal growth	0.776	0.224
G45.9 Transient cerebral ischaemic attack, unspecified	0.775	0.225
Chapter XXII Codes for special purposes	0.772	0.228
S20-S29 Injuries to the thorax	0.771	0.229
G45.3 Amaurosis fugax	0.770	0.230
I61 Intracerebral haemorrhage	0.769	0.231
O46 Antepartum haemorrhage, not elsewhere classified	0.769	0.231
I42 Cardiomyopathy	0.769	0.231
S50-S59 Injuries to the elbow and forearm	0.768	0.232
G55.2 Nerve root and plexus compressions in spondylosis	0.768	0.232
G95.9 Disease of spinal cord, unspecified	0.768	0.232
O36.8 Maternal care for other specified foetal problems	0.767	0.233
I25.5 Ischaemic cardiomyopathy	0.767	0.233
H65 Nonsuppurative otitis media	0.767	0.233
O03.4 Incomplete, without complication	0.766	0.234
O66 Other obstructed labour	0.763	0.237
S32.0 Fracture of lumbar vertebra	0.762	0.238
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.762	0.238
O26.9 Pregnancy-related condition, unspecified	0.761	0.239
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.757	0.243
E50-E64 Other nutritional deficiencies	0.757	0.243
I95 Hypotension	0.756	0.244
I30 Acute pericarditis	0.756	0.244
O41 Other disorders of amniotic fluid and membranes	0.756	0.244
I07 Rheumatic tricuspid valve diseases	0.755	0.245
O72 Postpartum haemorrhage	0.755	0.245
E83.5 Disorders of calcium metabolism	0.750	0.250
D51 Vitamin B12 deficiency anaemia	0.749	0.251
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.748	0.252
S00.7 Multiple superficial injuries of head	0.747	0.253
O94-O99 Other obstetric conditions, not elsewhere classified	0.746	0.254
I25.3 Aneurysm of heart	0.745	0.255
S92 Fracture of foot, except ankle	0.744	0.255
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.744	0.256
T20-T25 Burns and corrosions of external body surface, specified by site	0.743	0.257
G30-G32 Other degenerative diseases of the nervous system	0.741	0.259
E40-E46 Malnutrition	0.740	0.259
H61.8 Other specified disorders of external ear	0.738	0.262
I67 Other cerebrovascular diseases	0.737	0.263
E89.2 Postprocedural hypoparathyroidism	0.736	0.264
Q20-Q28 Congenital malformations of the circulatory system	0.736	0.264
Q50-Q56 Congenital malformations of genital organs	0.736	0.264
I63.9 Cerebral infarction, unspecified	0.734	0.266
D69 Purpura and other haemorrhagic conditions	0.733	0.267
O32 Maternal care for known or suspected malpresentation of foetus	0.733	0.267
O44 Placenta praevia	0.732	0.268
Q76 Congenital malformations of spine and bony thorax	0.732	0.268
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.732	0.268
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.731	0.269
E80 Disorders of porphyrin and bilirubin metabolism	0.731	0.269
I51.9 Heart disease, unspecified	0.731	0.269
H80-H83 Diseases of inner ear	0.730	0.270
O26.2 Pregnancy care of habitual aborter	0.729	0.270
I24.9 Acute ischaemic heart disease, unspecified	0.729	0.271
S09 Other and unspecified injuries of head	0.729	0.271
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.728	0.272
S32.00 Fracture of lumbar vertebra (closed)	0.728	0.272
I08.1 Disorders of both mitral and tricuspid valves	0.726	0.274
E89.3 Postprocedural hypopituitarism	0.725	0.275
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.724	0.275
S00.2 Other superficial injuries of eyelid and periocular area	0.722	0.278
O26.8 Other specified pregnancy-related conditions	0.721	0.279
G59 Mononeuropathy in diseases classified elsewhere	0.720	0.280
O90 Complications of the puerperium, not elsewhere classified	0.718	0.282
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
S00.5 Superficial injury of lip and oral cavity	0.715	0.285
G56.0 Carpal tunnel syndrome	0.714	0.286
I95.9 Hypotension, unspecified	0.713	0.287
G80-G83 Cerebral palsy and other paralytic syndromes	0.713	0.287
I22 Subsequent myocardial infarction	0.712	0.288
G95.1 Vascular myelopathies	0.711	0.289
I52 Other heart disorders in diseases classified elsewhere	0.711	0.289
I48 Atrial fibrillation and flutter	0.711	0.289
I43 Cardiomyopathy in diseases classified elsewhere	0.711	0.289
I41 Myocarditis in diseases classified elsewhere	0.711	0.289
I40 Acute myocarditis	0.711	0.289
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.711	0.289
I37 Pulmonary valve disorders	0.711	0.289
I36 Nonrheumatic tricuspid valve disorders	0.711	0.289
I32 Pericarditis in diseases classified elsewhere	0.711	0.289
O71 Other obstetric trauma	0.710	0.290
E85 Amyloidosis	0.709	0.290
E84 Cystic fibrosis	0.709	0.290
E79 Disorders of purine and pyrimidine metabolism	0.709	0.290
E77 Disorders of glycoprotein metabolism	0.709	0.290
E76 Disorders of glycosaminoglycan metabolism	0.709	0.290
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.709	0.290
E74 Other disorders of carbohydrate metabolism	0.709	0.290
E73 Lactose intolerance	0.709	0.290
E72 Other disorders of amino-acid metabolism	0.709	0.290
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.709	0.290
E70 Disorders of aromatic amino-acid metabolism	0.709	0.290
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.709	0.290
H61.2 Impacted cerumen	0.709	0.290
O62.2 Other uterine inertia	0.709	0.291
O24 Diabetes mellitus in pregnancy	0.708	0.292
E87.4 Mixed disorder of acid-base balance	0.707	0.293
O21 Excessive vomiting in pregnancy	0.707	0.293
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.707	0.293
G70-G73 Diseases of myoneural junction and muscle	0.706	0.294
I24.1 Dressler's syndrome	0.705	0.295
H61.0 Perichondritis of external ear	0.705	0.295
O40 Polyhydramnios	0.705	0.295
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.704	0.296
O87 Venous complications in the puerperium	0.704	0.296
I31 Other diseases of pericardium	0.704	0.296
Q38 Other congenital malformations of tongue, mouth and pharynx	0.703	0.297
I51.6 Cardiovascular disease, unspecified	0.702	0.297
I51.5 Myocardial degeneration	0.702	0.297
I51.3 Intracardiac thrombosis, not elsewhere classified	0.702	0.297
I51.2 Rupture of papillary muscle, not elsewhere classified	0.702	0.297
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.702	0.297
I51.0 Cardiac septal defect, acquired	0.702	0.297
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.703	0.297
O20.0 Threatened abortion	0.702	0.298
F80-F89 Disorders of psychological development	0.702	0.298
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.702	0.298
I61.9 Intracerebral haemorrhage, unspecified	0.701	0.299
G91.9 Hydrocephalus, unspecified	0.701	0.299
G93.4 Encephalopathy, unspecified	0.701	0.299
T15-T19 Effects of foreign body entering through natural orifice	0.701	0.299
O69.1 Labour and delivery complicated by cord around neck, with compression	0.701	0.299
O45 Premature separation of placenta [abruptio placentae]	0.700	0.300
O33 Maternal care for known or suspected disproportion	0.700	0.300
O31 Complications specific to multiple gestation	0.700	0.300
S01.0 Open wound of scalp	0.700	0.300
T33-T35 Frostbite	0.700	0.300
T26-T28 Burns and corrosions confined to eye and internal organs	0.700	0.300
T00-T07 Injuries involving multiple body regions	0.700	0.300
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.699	0.300
Q35-Q37 Cleft lip and cleft palate	0.699	0.300
Q30-Q34 Congenital malformations of the respiratory system	0.699	0.300
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.699	0.300
O02.1 Missed abortion	0.699	0.301
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.698	0.302
E16 Other disorders of pancreatic internal secretion	0.698	0.302
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.698	0.302
E20-E35 Disorders of other endocrine glands	0.693	0.307
H91.9 Hearing loss, unspecified	0.692	0.308
S70.9 Superficial injury of hip and thigh, unspecified	0.692	0.308
O74 Complications of anaesthesia during labour and delivery	0.691	0.309
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.691	0.309
O65 Obstructed labour due to maternal pelvic abnormality	0.691	0.309
O60 Preterm delivery	0.691	0.309
Q80-Q89 Other congenital malformations	0.689	0.310
O43 Placental disorders	0.689	0.311
G96 Other disorders of central nervous system	0.689	0.311
E83.3 Disorders of phosphorus metabolism	0.688	0.312
O29 Complications of anaesthesia during pregnancy	0.687	0.313
O28 Abnormal findings on antenatal screening of mother	0.687	0.313
O23 Infections of genito-urinary tract in pregnancy	0.687	0.313
O22 Venous complications in pregnancy	0.687	0.313
O25 Malnutrition in pregnancy	0.687	0.313
Q39 Congenital malformations of oesophagus	0.685	0.315
H93.1 Tinnitus	0.685	0.315
Q65 Congenital deformities of hip	0.684	0.316
H61.3 Acquired stenosis of external ear canal	0.684	0.316
G90 Disorders of autonomic nervous system	0.683	0.317
G94 Other disorders of brain in diseases classified elsewhere	0.682	0.318
G98 Other disorders of nervous system, not elsewhere classified	0.682	0.318
G92 Toxic encephalopathy	0.682	0.318
S00.1 Contusion of eyelid and periocular area	0.681	0.319
G52 Disorders of other cranial nerves	0.681	0.319
G95.2 Cord compression, unspecified	0.681	0.319
I34.8 Other nonrheumatic mitral valve disorders	0.680	0.320
S08 Traumatic amputation of part of head	0.680	0.320
S07 Crushing injury of head	0.680	0.320
S04 Injury of cranial nerves	0.680	0.320
S03 Dislocation, sprain and strain of joints and ligaments of head	0.680	0.320
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.679	0.321
I50.9 Heart failure, unspecified	0.679	0.321
T79-T79 Certain early complications of trauma	0.679	0.321
O86 Other puerperal infections	0.678	0.322
S01.7 Multiple open wounds of head	0.678	0.322
H91.8 Other specified hearing loss	0.678	0.322
O34 Maternal care for known or suspected abnormality of pelvic organs	0.678	0.322
G50 Disorders of trigeminal nerve	0.676	0.324
F40-F48 Neurotic, stress-related and somatoform disorders	0.675	0.325
O00 Ectopic pregnancy	0.674	0.326
S51 Open wound of forearm	0.673	0.327
G57 Mononeuropathies of lower limb	0.673	0.327
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.673	0.327
E89.8 Other postprocedural endocrine and metabolic disorders	0.673	0.327
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.673	0.327
E89.5 Postprocedural testicular hypofunction	0.673	0.327
E89.4 Postprocedural ovarian failure	0.673	0.327
E89.1 Postprocedural hypoinsulinaemia	0.673	0.327
D70-D77 Other diseases of blood and blood-forming organs	0.672	0.328
G58 Other mononeuropathies	0.672	0.328
E83.9 Disorder of mineral metabolism, unspecified	0.671	0.328
E83.8 Other disorders of mineral metabolism	0.671	0.328
E83.2 Disorders of zinc metabolism	0.671	0.328
E83.0 Disorders of copper metabolism	0.671	0.328
E83.1 Disorders of iron metabolism	0.671	0.329
G45.4 Transient global amnesia	0.671	0.329
I09 Other rheumatic heart diseases	0.670	0.330
I06 Rheumatic aortic valve diseases	0.670	0.330
I05 Rheumatic mitral valve diseases	0.669	0.331
I67.9 Cerebrovascular disease, unspecified	0.669	0.331
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.669	0.331
T66-T78 Other and unspecified effects of external causes	0.668	0.332
O36.9 Maternal care for foetal problem, unspecified	0.668	0.332
O73 Retained placenta and membranes, without haemorrhage	0.667	0.332
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.667	0.333
S70.1 Contusion of thigh	0.667	0.333
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.667	0.333
O80 Single spontaneous delivery	0.666	0.333
H65.4 Other chronic nonsuppurative otitis media	0.665	0.335
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.660	0.340
G03 Meningitis due to other and unspecified causes	0.660	0.340
G40.8 Other epilepsy	0.660	0.340
G53 Cranial nerve disorders in diseases classified elsewhere	0.660	0.340
S00.4 Superficial injury of ear	0.658	0.342
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.658	0.342
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.658	0.342
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.658	0.342
G44 Other headache syndromes	0.657	0.342
S10-S19 Injuries to the neck	0.657	0.343
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.656	0.344
G54 Nerve root and plexus disorders	0.656	0.344
S92.3 Fracture of metatarsal bone	0.656	0.344
H62 Disorders of external ear in diseases classified elsewhere	0.655	0.345
O08 Complications following abortion and ectopic and molar pregnancy	0.655	0.345
O07 Failed attempted abortion	0.655	0.345
O06 Unspecified abortion	0.655	0.345
O05 Other abortion	0.655	0.345
O01 Hydatidiform mole	0.655	0.345
G40.9 Epilepsy, unspecified	0.655	0.345
E88 Other metabolic disorders	0.654	0.346
F60-F69 Disorders of adult personality and behaviour	0.654	0.346
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.653	0.347
H61.1 Non-infective disorders of pinna	0.653	0.347
G51 Facial nerve disorders	0.652	0.348
G46 Vascular syndromes of brain in cerebrovascular diseases	0.651	0.349
S00.3 Superficial injury of nose	0.650	0.350
G93.9 Disorder of brain, unspecified	0.650	0.350
O61 Failed induction of labour	0.648	0.351
G41 Status epilepticus	0.648	0.352
H94 Other disorders of ear in diseases classified elsewhere	0.648	0.352
I46 Cardiac arrest	0.648	0.352
Chapter VII Diseases of the eye and adnexa	0.646	0.354
S83.2 Tear of meniscus, current	0.645	0.355
O62.3 Precipitate labour	0.645	0.355
S05.9 Injury of eye and orbit, part unspecified	0.644	0.356
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.644	0.356
O75.7 Vaginal delivery following previous Caesarean section	0.644	0.356
Q76.0 Spina bifida occulta	0.644	0.356
D55-D59 Haemolytic anaemias	0.641	0.359
D69.6 Thrombocytopenia, unspecified	0.641	0.359
O42.2 Premature rupture of membranes, labour delayed by therapy	0.640	0.360
S71 Open wound of hip and thigh	0.640	0.360
H69 Other disorders of Eustachian tube	0.640	0.360
Q07 Other congenital malformations of nervous system	0.639	0.361
G06 Intracranial and intraspinal abscess and granuloma	0.638	0.362
H60 Otitis externa	0.637	0.363
O20.9 Haemorrhage in early pregnancy, unspecified	0.637	0.363
Q43 Other congenital malformations of intestine	0.636	0.364
G95.8 Other specified diseases of spinal cord	0.636	0.364
Q61 Cystic kidney disease	0.636	0.364
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.635	0.365
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.635	0.365
O26.5 Maternal hypotension syndrome	0.635	0.365
O26.4 Herpes gestationis	0.635	0.365
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.635	0.365
O26.1 Low weight gain in pregnancy	0.635	0.365
O26.0 Excessive weight gain in pregnancy	0.635	0.365
O72.2 Delayed and secondary postpartum haemorrhage	0.635	0.365
S30 Superficial injury of abdomen, lower back and pelvis	0.631	0.369
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.629	0.371
O92 Other disorders of breast and lactation associated with childbirth	0.628	0.371
O91 Infections of breast associated with childbirth	0.628	0.371
O89 Complications of anaesthesia during the puerperium	0.628	0.371
O88 Obstetric embolism	0.628	0.371
O85 Puerperal sepsis	0.628	0.371
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.628	0.372
E87.3 Alkalosis	0.628	0.372
O62.0 Primary inadequate contractions	0.628	0.372
I99 Other and unspecified disorders of circulatory system	0.628	0.372
O66.0 Obstructed labour due to shoulder dystocia	0.628	0.372
G95.0 Syringomyelia and syringobulbia	0.628	0.372
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.628	0.372
I07.1 Tricuspid insufficiency	0.626	0.374
G55.0 Nerve root and plexus compressions in neoplastic disease	0.625	0.375
S81 Open wound of lower leg	0.624	0.376
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.624	0.376
O36.4 Maternal care for intra-uterine death	0.624	0.376
O36.3 Maternal care for signs of foetal hypoxia	0.624	0.376
O36.2 Maternal care for hydrops foetalis	0.624	0.376
O36.1 Maternal care for other isoimmunisation	0.624	0.376
O46.8 Other antepartum haemorrhage	0.624	0.376
H66 Suppurative and unspecified otitis media	0.623	0.377
G45.2 Multiple and bilateral precerebral artery syndromes	0.623	0.377
G45.1 Carotid artery syndrome (hemispheric)	0.623	0.377
G45.0 Vertebro-basilar artery syndrome	0.623	0.377
Chapter XII Diseases of the skin and subcutaneous tissue	0.622	0.378
S40-S49 Injuries to the shoulder and upper arm	0.621	0.378
I08.9 Multiple valve disease, unspecified	0.621	0.379
I08.2 Disorders of both aortic and tricuspid valves	0.621	0.379
H61.9 Disorder of external ear, unspecified	0.621	0.379
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.621	0.379
S37 Injury of urinary and pelvic organs	0.621	0.379
S36 Injury of intra-abdominal organs	0.621	0.379
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.621	0.379
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.621	0.379
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.621	0.379
S31 Open wound of abdomen, lower back and pelvis	0.621	0.379
I42.6 Alcoholic cardiomyopathy	0.619	0.381
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.618	0.382
H10-H13 Disorders of conjunctiva	0.618	0.382
Q45 Other congenital malformations of digestive system	0.617	0.383
Q42 Congenital absence, atresia and stenosis of large intestine	0.617	0.383
Q41 Congenital absence, atresia and stenosis of small intestine	0.617	0.383
Q40 Other congenital malformations of upper alimentary tract	0.617	0.383
S01.8 Open wound of other parts of head	0.617	0.383
I08.8 Other multiple valve diseases	0.616	0.383
I47.2 Ventricular tachycardia	0.617	0.383
F99-F99 Unspecified mental disorder	0.616	0.383
S32.4 Fracture of acetabulum	0.616	0.383
G04 Encephalitis, myelitis and encephalomyelitis	0.616	0.384
S79 Other and unspecified injuries of hip and thigh	0.616	0.384
S78 Traumatic amputation of hip and thigh	0.616	0.384
S77 Crushing injury of hip and thigh	0.616	0.384
S76 Injury of muscle and tendon at hip and thigh level	0.616	0.384
S75 Injury of blood vessels at hip and thigh level	0.616	0.384
S74 Injury of nerves at hip and thigh level	0.616	0.384
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.616	0.384
D69.3 Idiopathic thrombocytopenic purpura	0.615	0.385
H65.9 Nonsuppurative otitis media, unspecified	0.615	0.385
I34.0 Mitral (valve) insufficiency	0.614	0.386
I68 Cerebrovascular disorders in diseases classified elsewhere	0.614	0.386
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.614	0.386
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.613	0.387
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.613	0.387
Q78 Other osteochondrodysplasias	0.613	0.387
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.613	0.387
Q75 Other congenital malformations of skull and face bones	0.613	0.387
Q74 Other congenital malformations of limb(s)	0.613	0.387
Q73 Reduction defects of unspecified limb	0.613	0.387
Q72 Reduction defects of lower limb	0.613	0.387
Q71 Reduction defects of upper limb	0.613	0.387
Q70 Syndactyly	0.613	0.387
Q69 Polydactyly	0.613	0.387
Q68 Other congenital musculoskeletal deformities	0.613	0.387
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.613	0.387
Q66 Congenital deformities of feet	0.613	0.387
S01.4 Open wound of cheek and temporomandibular area	0.613	0.387
Q60 Renal agenesis and other reduction defects of kidney	0.613	0.387
H74 Other disorders of middle ear and mastoid	0.613	0.387
I47.9 Paroxysmal tachycardia, unspecified	0.612	0.388
S99 Other and unspecified injuries of ankle and foot	0.611	0.389
S98 Traumatic amputation of ankle and foot	0.611	0.389
S97 Crushing injury of ankle and foot	0.611	0.389
S96 Injury of muscle and tendon at ankle and foot level	0.611	0.389
S95 Injury of blood vessels at ankle and foot level	0.611	0.389
S94 Injury of nerves at ankle and foot level	0.611	0.389
E16.2 Hypoglycaemia, unspecified	0.611	0.389
Q05 Spina bifida	0.609	0.391
O80.0 Spontaneous vertex delivery	0.609	0.391
I60 Subarachnoid haemorrhage	0.609	0.391
O62.9 Abnormality of forces of labour, unspecified	0.608	0.392
O62.8 Other abnormalities of forces of labour	0.608	0.392
O62.1 Secondary uterine inertia	0.608	0.392
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.608	0.392
S22 Fracture of rib(s), sternum and thoracic spine	0.608	0.392
S86 Injury of muscle and tendon at lower leg level	0.607	0.393
I63.8 Other cerebral infarction	0.607	0.393
H73 Other disorders of tympanic membrane	0.605	0.395
O90.1 Disruption of perineal obstetric wound	0.605	0.395
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.604	0.396
H70 Mastoiditis and related conditions	0.604	0.396
H68 Eustachian salpingitis and obstruction	0.604	0.396
H67 Otitis media in diseases classified elsewhere	0.604	0.396
O75.2 Pyrexia during labour, not elsewhere classified	0.603	0.397
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.602	0.398
F70-F79 Mental retardation	0.602	0.398
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.602	0.398
H65.3 Chronic mucoid otitis media	0.602	0.398
H11 Other disorders of conjunctiva	0.602	0.398
S32.3 Fracture of ilium	0.600	0.399
S50 Superficial injury of forearm	0.600	0.400
E55 Vitamin D deficiency	0.600	0.400
F43 Reaction to severe stress, and adjustment disorders	0.599	0.401
S91 Open wound of ankle and foot	0.599	0.401
S20 Superficial injury of thorax	0.598	0.402
O41.0 Oligohydramnios	0.598	0.402
E65-E68 Obesity and other hyperalimentation	0.596	0.404
Chapter I Certain infectious and parasitic diseases	0.595	0.405
S88 Traumatic amputation of lower leg	0.595	0.405
S87 Crushing injury of lower leg	0.595	0.405

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations