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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Hospitalization Episode Statistics (HES)

I06.1
Rheumatic aortic insufficiency
Parent term
I06 Rheumatic aortic valve diseases
What are diagnostic terms?
Variant effects

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
rs73542936 lBF = 11.6477   Chr8 : 1,839,557
0.497 0.502 0.000
rs79767168 lBF = 18.8427   Chr8 : 131,516,058
0.497 0.503 0.000
rs73210044 lBF = 15.2486   Chr8 : 13,392,360
0.492 0.508 0.000
rs78216664 lBF = 7.58546   Chr8 : 32,068,317
0.484 0.516 0.000
rs117172322 lBF = 9.83651   Chr8 : 39,522,372
0.483 0.517 0.000
rs75323949 lBF = 6.24792   Chr8 : 69,545,445
0.481 0.519 0.000
rs17423218 lBF = 17.6829   Chr8 : 67,758,401
0.477 0.523 0.000
rs16893349 lBF = 16.5225   Chr8 : 134,207,963
0.473 0.527 0.000
rs17797221 lBF = 24.1427   Chr8 : 97,995,627
0.469 0.530 0.000
rs75779669 lBF = 19.3932   Chr8 : 20,955,032
0.469 0.531 0.000
rs72649226 lBF = 15.4053   Chr8 : 64,550,665
0.466 0.534 0.000
rs6983561 lBF = 16.9301   Chr8 : 128,106,880
0.460 0.540 0.000
rs10505483 lBF = 15.7887   Chr8 : 128,125,195
0.459 0.541 0.000
rs12682344 lBF = 16.2953   Chr8 : 128,106,784
0.458 0.542 0.000
rs17829719 lBF = 15.2172   Chr8 : 1,824,454
0.458 0.542 0.000
rs7830341 lBF = 16.3042   Chr8 : 128,109,930
0.457 0.542 0.000
rs77453333 lBF = 13.3291   Chr8 : 8,514,483
0.456 0.544 0.000
rs16901979 lBF = 15.3333   Chr8 : 128,124,916
0.454 0.546 0.000
rs77119043 lBF = 15.2787   Chr8 : 48,313,295
0.454 0.546 0.000
rs73302752 lBF = 21.6628   Chr8 : 73,279,185
0.452 0.548 0.000
rs77205825 lBF = 25.6929   Chr8 : 140,470,489
0.446 0.554 0.000
rs80343479 lBF = 10.9579   Chr8 : 16,386,058
0.444 0.556 0.000
rs117956319 lBF = 13.4307   Chr8 : 32,191,896
0.442 0.557 0.000
rs17727296 lBF = 13.2947   Chr8 : 72,558,829
0.440 0.560 0.000
rs117194321 lBF = 19.8711   Chr8 : 22,491,317
0.432 0.567 0.000
rs117336177 lBF = 15.6541   Chr8 : 66,701,846
0.430 0.570 0.000
rs74357743 lBF = 13.6586   Chr8 : 74,712,506
0.429 0.571 0.000
rs141527659 lBF = 22.6507   Chr8 : 130,875,935
0.426 0.574 0.000
rs118030566 lBF = 27.3147   Chr8 : 144,403,041
0.424 0.576 0.000
rs188420713 lBF = 2.98848   Chr8 : 37,134,189
0.422 0.578 0.000
rs186868868 lBF = 23.5439   Chr8 : 19,863,803
0.419 0.581 0.000
rs112767144 lBF = 30.2394   Chr8 : 134,263,916
0.418 0.581 0.000
rs72630661 lBF = 19.6221   Chr8 : 38,329,982
0.418 0.582 0.000
rs6984045 lBF = 7.25756   Chr8 : 131,092,413
0.418 0.582 0.000
rs150488832 lBF = 17.2688   Chr8 : 36,201,248
0.417 0.583 0.000
rs1441759 lBF = 22.8185   Chr8 : 19,865,563
0.417 0.583 0.000
rs79917365 lBF = 15.1303   Chr8 : 67,459,400
0.415 0.585 0.000
rs72659626 lBF = 18.2705   Chr8 : 72,920,433
0.414 0.585 0.000
rs479798 lBF = 14.5952   Chr8 : 29,112,073
0.413 0.586 0.000
rs78586881 lBF = 15.3006   Chr8 : 37,144,739
0.412 0.588 0.000
rs77237430 lBF = 10.8581   Chr8 : 117,500,622
0.410 0.590 0.000
rs77822622 lBF = 16.7219   Chr8 : 57,929,662
0.409 0.590 0.000
rs117531883 lBF = 20.9443   Chr8 : 8,309,054
0.408 0.591 0.000
rs74566133 lBF = 21.6776   Chr8 : 134,778,342
0.406 0.593 0.000
rs2132138 lBF = 13.4027   Chr8 : 15,386,569
0.406 0.593 0.000
rs2351326 lBF = 12.3551   Chr8 : 111,847,246
0.406 0.594 0.000
rs118182320 lBF = 24.3873   Chr8 : 80,951,882
0.404 0.595 0.000
rs80029792 lBF = 24.0731   Chr8 : 134,781,276
0.404 0.595 0.000
rs73660508 lBF = 6.12279   Chr8 : 5,942,562
0.402 0.597 0.000
rs117984108 lBF = 20.8253   Chr8 : 22,983,095
0.401 0.599 0.000
rs117262625 lBF = 15.8812   Chr8 : 21,089,037
0.397 0.603 0.000
rs80058714 lBF = 10.9735   Chr8 : 131,408,366
0.395 0.605 0.000
rs60336366 lBF = 2.08613   Chr8 : 114,662,251
0.392 0.608 0.000
rs79816080 lBF = 14.832   Chr8 : 36,420,485
0.391 0.609 0.000
rs2106212 lBF = 24.403   Chr8 : 12,569,241
0.390 0.610 0.000
rs117405208 lBF = 11.2682   Chr8 : 134,967,408
0.389 0.611 0.000
rs116086868 lBF = 14.4058   Chr8 : 17,448,828
0.389 0.611 0.000
rs56109708 lBF = 17.2043   Chr8 : 140,438,978
0.389 0.611 0.000
rs78198802 lBF = 14.2898   Chr8 : 22,900,168
0.388 0.612 0.000
rs6987665 lBF = 17.3248   Chr8 : 67,655,175
0.386 0.614 0.000
rs113040697 lBF = 28.1855   Chr8 : 118,185,308
0.380 0.620 0.000
rs111726812 lBF = 16.437   Chr8 : 123,965,193
0.378 0.622 0.000
rs117809070 lBF = 22.8902   Chr8 : 67,282,208
0.377 0.623 0.000
rs117500008 lBF = 15.3496   Chr8 : 101,671,045
0.377 0.623 0.000
rs73204665 lBF = 14.5549   Chr8 : 9,621,236
0.377 0.623 0.000
rs72655627 lBF = 15.4721   Chr8 : 55,287,974
0.376 0.624 0.000
rs28514585 lBF = 20.0653   Chr8 : 129,636,084
0.376 0.624 0.000
rs71522756 lBF = 14.0585   Chr8 : 106,746,337
0.375 0.624 0.000
rs17372597 lBF = 15.796   Chr8 : 125,595,153
0.371 0.628 0.000
rs116424300 lBF = 20.3133   Chr8 : 143,412,988
0.370 0.629 0.000
rs16876083 lBF = 1.85429   Chr8 : 29,716,261
0.368 0.631 0.000
rs7386241 lBF = 16.8881   Chr8 : 139,240,856
0.367 0.632 0.000
rs185206099 lBF = 1.92922   Chr8 : 6,477,298
0.000 0.637 0.363
rs191939331 lBF = 1.86657   Chr8 : 84,717,650
0.362 0.637 0.000
rs77173849 lBF = 16.2623   Chr8 : 47,021,723
0.362 0.637 0.000
rs117402109 lBF = 17.7054   Chr8 : 108,708,382
0.362 0.638 0.000
rs116951791 lBF = 8.04751   Chr8 : 93,219,721
0.361 0.639 0.000
rs184060364 lBF = 1.31395   Chr8 : 84,120,968
0.361 0.639 0.000
rs78714084 lBF = 18.8347   Chr8 : 89,031,066
0.358 0.641 0.000
rs187700680 lBF = 24.0087   Chr8 : 15,377,498
0.356 0.643 0.000
rs74342708 lBF = 21.3644   Chr8 : 22,572,749
0.355 0.645 0.000
rs13248930 lBF = 6.94247   Chr8 : 125,664,204
0.349 0.651 0.000
rs28603047 lBF = 14.1451   Chr8 : 108,826,197
0.348 0.651 0.000
rs118124984 lBF = 22.9554   Chr8 : 106,184,779
0.347 0.653 0.000
rs77959025 lBF = 16.9241   Chr8 : 128,761,169
0.343 0.657 0.000
rs117926607 lBF = 23.2066   Chr8 : 55,468,849
0.342 0.657 0.000
rs268 lBF = 17.5199   Chr8 : 19,813,529
0.342 0.658 0.000
rs75835816 lBF = 7.35402   Chr8 : 19,885,513
0.342 0.658 0.000
rs117192105 lBF = 15.7523   Chr8 : 24,498,050
0.342 0.658 0.000
rs10089409 lBF = 7.8989   Chr8 : 111,665,189
0.342 0.658 0.000
rs79512063 lBF = 24.6388   Chr8 : 89,533,747
0.338 0.662 0.000
rs2648908 lBF = 12.2754   Chr8 : 129,127,594
0.338 0.662 0.000
rs188140481 lBF = 18.2034   Chr8 : 128,191,672
0.336 0.663 0.000
rs13251303 lBF = 21.0972   Chr8 : 34,230,938
0.335 0.665 0.000
rs140273521 lBF = 15.1391   Chr8 : 136,277,752
0.334 0.666 0.000
rs74912350 lBF = 10.4081   Chr8 : 96,035,756
0.332 0.668 0.000
rs80301223 lBF = 12.0195   Chr8 : 119,648,160
0.332 0.668 0.000
rs10108669 lBF = 24.3176   Chr8 : 108,685,885
0.329 0.670 0.000
rs1801177 lBF = 13.37   Chr8 : 19,805,708
0.326 0.673 0.000
rs118053264 lBF = 15.1239   Chr8 : 19,356,779
0.324 0.676 0.000
rs16905439 lBF = 6.71325   Chr8 : 136,989,204
0.323 0.677 0.000
rs74896277 lBF = 17.349   Chr8 : 131,131,148
0.322 0.678 0.000
rs7823724 lBF = 6.06735   Chr8 : 141,404,329
0.321 0.678 0.000
rs75631105 lBF = 17.5459   Chr8 : 141,449,601
0.321 0.679 0.000
rs35868637 lBF = 14.7865   Chr8 : 94,743,876
0.321 0.679 0.000
rs17654611 lBF = 16.7861   Chr8 : 139,156,782
0.321 0.679 0.000
rs17057381 lBF = 1.98864   Chr8 : 27,416,801
0.319 0.681 0.000
rs76594396 lBF = 11.0301   Chr8 : 5,443,735
0.316 0.684 0.000
rs142507408 lBF = 2.75227   Chr8 : 106,455,558
0.313 0.687 0.000
rs138042437 lBF = 17.9564   Chr8 : 128,208,369
0.311 0.689 0.000
rs77942316 lBF = 2.53949   Chr8 : 92,359,337
0.308 0.692 0.000
rs150639459 lBF = 11.2123   Chr8 : 18,804,686
0.306 0.693 0.000
rs79922463 lBF = 6.09241   Chr8 : 112,002,658
0.305 0.695 0.000
rs75583295 lBF = 19.5736   Chr8 : 63,596,650
0.304 0.696 0.000
rs16902048 lBF = 13.4263   Chr8 : 128,243,131
0.303 0.696 0.000
rs72668436 lBF = 5.13152   Chr8 : 99,917,181
0.295 0.705 0.000
rs67455183 lBF = 5.50415   Chr8 : 10,145,925
0.000 0.706 0.293
rs62495153 lBF = 7.67204   Chr8 : 8,136,656
0.293 0.706 0.000
rs76904521 lBF = 9.88184   Chr8 : 1,148,999
0.292 0.708 0.000
rs74617895 lBF = 13.7107   Chr8 : 3,646,688
0.286 0.714 0.000
rs117857023 lBF = 14.423   Chr8 : 10,675,065
0.281 0.719 0.000
rs117206365 lBF = 12.4837   Chr8 : 126,883,835
0.267 0.732 0.000
rs62501302 lBF = 17.5576   Chr8 : 50,545,426
0.266 0.733 0.000
rs17250031 lBF = 17.4462   Chr8 : 75,077,959
0.261 0.739 0.000
rs16879552 lBF = 5.16584   Chr8 : 32,411,216
0.259 0.741 0.000
rs187162159 lBF = 0.854917   Chr8 : 25,111,606
0.255 0.745 0.000
rs830478 lBF = 9.24249   Chr8 : 73,372,875
0.254 0.746 0.000
rs13277394 lBF = 8.77619   Chr8 : 18,266,219
0.252 0.748 0.000
rs11784849 lBF = 14.957   Chr8 : 75,144,736
0.249 0.751 0.000
rs117438523 lBF = 14.3842   Chr8 : 14,577,786
0.246 0.754 0.000
rs113465333 lBF = 13.2764   Chr8 : 129,756,647
0.245 0.755 0.000
rs34120730 lBF = 12.3059   Chr8 : 75,405,303
0.244 0.755 0.000
rs77616023 lBF = 8.20137   Chr8 : 57,336,601
0.235 0.764 0.000
rs75417855 lBF = 21.8115   Chr8 : 8,966,147
0.234 0.765 0.000
rs79369118 lBF = 12.8136   Chr8 : 89,693,007
0.225 0.774 0.000
rs61729951 lBF = 15.1399   Chr8 : 10,532,188
0.221 0.779 0.000
rs16867579 lBF = 0.536426   Chr8 : 102,375,267
0.219 0.781 0.000
rs13266556 lBF = 7.6967   Chr8 : 85,657,036
0.218 0.782 0.000
rs62511613 lBF = 11.9042   Chr8 : 34,178,686
0.215 0.784 0.000
rs7011581 lBF = 17.2432   Chr8 : 9,000,465
0.215 0.785 0.000
rs183826639 lBF = 0.489777   Chr8 : 76,817,264
0.215 0.785 0.000
rs7829065 lBF = 8.29515   Chr8 : 9,396,649
0.207 0.792 0.000
rs12676637 lBF = 6.77263   Chr8 : 15,770,661
0.206 0.794 0.000
rs6995588 lBF = 1.80835   Chr8 : 61,003,897
0.201 0.799 0.000
rs140707667 lBF = 0.322695   Chr8 : 84,028,528
0.187 0.812 0.000
rs7815944 lBF = 3.84103   Chr8 : 129,427,518
0.181 0.819 0.000
rs76308827 lBF = 22.5688   Chr8 : 80,264,727
0.179 0.821 0.000
rs10108954 lBF = 1.89999   Chr8 : 8,722,378
0.176 0.823 0.000
rs62532816 lBF = 24.7031   Chr8 : 132,554,452
0.176 0.824 0.000
rs2083637 lBF = 18.8278   Chr8 : 19,865,175
0.000 0.832 0.168
rs9656829 lBF = 8.16676   Chr8 : 93,602,448
0.166 0.834 0.000
rs80299072 lBF = 15.8593   Chr8 : 36,556,762
0.155 0.845 0.000
rs3748140 lBF = 15.9864   Chr8 : 8,999,019
0.154 0.846 0.000
rs117873316 lBF = 14.6834   Chr8 : 135,652,254
0.153 0.847 0.000
rs117628011 lBF = 0.242073   Chr8 : 76,319,166
0.148 0.851 0.000
rs74664674 lBF = 18.0774   Chr8 : 105,468,730
0.147 0.852 0.001
rs17489373 lBF = 16.1189   Chr8 : 19,855,344
0.000 0.853 0.146
rs331 lBF = 17.9407   Chr8 : 19,820,405
0.000 0.854 0.146
rs1441756 lBF = 18.4586   Chr8 : 19,868,386
0.000 0.855 0.144
rs16938910 lBF = 0.223122   Chr8 : 75,373,948
0.142 0.857 0.000
rs9918841 lBF = 16.249   Chr8 : 91,193,959
0.137 0.863 0.000
rs4873403 lBF = 0.22757   Chr8 : 50,974,319
0.136 0.863 0.000
rs320 lBF = 15.1988   Chr8 : 19,819,077
0.000 0.877 0.122
rs61134957 lBF = 0.280178   Chr8 : 92,599,003
0.114 0.886 0.000
rs149038799 lBF = 3.1664   Chr8 : 123,458,462
0.111 0.888 0.000
rs79560598 lBF = 14.8051   Chr8 : 40,540,751
0.111 0.889 0.000
rs295 lBF = 5.95375   Chr8 : 19,816,238
0.000 0.893 0.106
rs6989010 lBF = 0.220835   Chr8 : 12,772,755
0.102 0.898 0.000
rs7001413 lBF = 5.40312   Chr8 : 75,010,233
0.100 0.900 0.000
rs301 lBF = 5.37678   Chr8 : 19,816,934
0.000 0.901 0.099
rs60078135 lBF = 5.25935   Chr8 : 1,082,832
0.092 0.908 0.000
rs16910714 lBF = 6.38134   Chr8 : 140,496,702
0.091 0.909 0.000
rs13702 lBF = 18.3151   Chr8 : 19,824,492
0.000 0.913 0.087
rs187899339 lBF = 1.40307   Chr8 : 111,118,450
0.086 0.913 0.000
rs62502258 lBF = 5.08734   Chr8 : 23,852,510
0.085 0.914 0.001
rs9644568 lBF = 5.96243   Chr8 : 19,928,582
0.000 0.914 0.085
rs75038381 lBF = 11.7333   Chr8 : 102,017,153
0.081 0.918 0.000
rs77541621 lBF = 26.0542   Chr8 : 128,077,146
0.073 0.927 0.000
rs15285 lBF = 20.0574   Chr8 : 19,824,667
0.000 0.930 0.069
rs117366179 lBF = 16.6572   Chr8 : 14,733,658
0.067 0.932 0.000
rs78894544 lBF = 7.29453   Chr8 : 138,323,083
0.066 0.933 0.000
rs1905321 lBF = 6.29726   Chr8 : 90,220,346
0.065 0.935 0.000
rs75729198 lBF = 19.6792   Chr8 : 15,885,087
0.064 0.936 0.000
rs80054318 lBF = 14.188   Chr8 : 50,129,604
0.060 0.940 0.000
rs4397449 lBF = 0.0854969   Chr8 : 90,342,186
0.000 0.941 0.059
rs7461360 lBF = 1.91134   Chr8 : 68,678,150
0.058 0.942 0.000
rs16924527 lBF = 0.0720799   Chr8 : 59,974,175
0.051 0.948 0.000
rs326 lBF = 15.1404   Chr8 : 19,819,439
0.000 0.951 0.048
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0.044 0.956 0.000
rs17237902 lBF = 11.6133   Chr8 : 104,929,497
0.039 0.960 0.000
rs4921542 lBF = 5.71395   Chr8 : 17,205,577
0.037 0.962 0.000
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0.036 0.964 0.001
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0.034 0.966 0.000
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0.033 0.966 0.000
rs17740640 lBF = 5.1173   Chr8 : 1,005,427
0.032 0.968 0.000
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0.030 0.970 0.000
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0.000 0.970 0.029
rs7459527 lBF = 0.0670646   Chr8 : 118,909,260
0.029 0.971 0.000
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0.025 0.975 0.000
rs7016880 lBF = 3.47103   Chr8 : 19,876,746
0.000 0.975 0.025
rs56229264 lBF = 17.6142   Chr8 : 27,321,189
0.024 0.976 0.000
rs800586 lBF = 0.947739   Chr8 : 116,813,905
0.018 0.976 0.007
rs2304877 lBF = 8.23168   Chr8 : 41,566,438
0.024 0.976 0.000
rs6601606 lBF = 0.475405   Chr8 : 11,638,244
0.023 0.976 0.000
rs72657954 lBF = 0.0302208   Chr8 : 72,770,306
0.023 0.976 0.000
rs16888648 lBF = 8.01812   Chr8 : 39,884,165
0.023 0.976 0.000
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0.000 0.977 0.023
rs4416828 lBF = 6.22936   Chr8 : 24,468,982
0.020 0.980 0.001
rs2357667 lBF = 2.503   Chr8 : 66,955,437
0.020 0.980 0.000
rs4645543 lBF = 3.51242   Chr8 : 140,496,242
0.015 0.984 0.000
rs62522179 lBF = 0.0435349   Chr8 : 142,154,696
0.015 0.984 0.000
rs4872511 lBF = 0.0384953   Chr8 : 22,400,989
0.015 0.984 0.000
rs7833294 lBF = 1.28762   Chr8 : 58,008,281
0.008 0.985 0.008
rs34665903 lBF = 7.545   Chr8 : 62,699,372
0.014 0.985 0.001
rs2720508 lBF = 0.0204018   Chr8 : 17,329,827
0.000 0.985 0.015
rs117933211 lBF = 0.115108   Chr8 : 47,243,611
0.014 0.985 0.000
rs77303430 lBF = 9.49687   Chr8 : 99,875,745
0.014 0.986 0.000
rs2981145 lBF = 12.2328   Chr8 : 39,865,119
0.014 0.986 0.000
rs1059611 lBF = 3.30576   Chr8 : 19,824,563
0.000 0.987 0.013
rs74343026 lBF = 6.74894   Chr8 : 126,258,883
0.012 0.987 0.000
rs325 lBF = 5.51521   Chr8 : 19,819,328
0.000 0.988 0.012
rs6995402 lBF = 1.68623   Chr8 : 145,005,561
0.011 0.989 0.000
rs59294057 lBF = 0.0130314   Chr8 : 21,506,668
0.011 0.989 0.000
rs76670418 lBF = 10.9855   Chr8 : 60,334,045
0.011 0.989 0.000
rs117577998 lBF = 13.0097   Chr8 : 143,505,653
0.011 0.989 0.000
rs328 lBF = 4.32431   Chr8 : 19,819,724
0.000 0.990 0.010
rs17186334 lBF = 10.5242   Chr8 : 13,046,662
0.009 0.991 0.000
rs72657970 lBF = 0.0131775   Chr8 : 72,808,087
0.009 0.991 0.000
rs17321515 lBF = 32.222   Chr8 : 126,486,409
0.000 0.991 0.009
rs145959269 lBF = 3.70784   Chr8 : 143,357,023
0.008 0.991 0.000
rs76188673 lBF = 12.8925   Chr8 : 2,443,492
0.008 0.992 0.000
rs4469412 lBF = 3.23679   Chr8 : 33,565,378
0.008 0.992 0.000
rs10503253 lBF = 0.605522   Chr8 : 4,180,844
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0.000 0.999 0.000
rs17665859 lBF = 0.377724   Chr8 : 445,601
0.000 0.999 0.000
rs1585518 lBF = 0.0706345   Chr8 : 120,475,238
0.000 0.999 0.001
rs10097555 lBF = -0.0673728   Chr8 : 32,346,295
0.000 0.999 0.001
rs2954038 lBF = 34.2663   Chr8 : 126,507,389
0.000 0.999 0.000
rs2162460 lBF = 5.78382   Chr8 : 59,331,781
0.001 0.999 0.000
rs6986153 lBF = 1.30611   Chr8 : 108,072,044
0.001 0.999 0.000
rs17766217 lBF = 0.572149   Chr8 : 128,504,497
0.000 0.999 0.001
rs4732812 lBF = 0.155874   Chr8 : 27,923,388
0.000 0.999 0.000
rs7833986 lBF = 0.0179907   Chr8 : 57,100,149
0.000 0.999 0.001
rs10504249 lBF = 0.015296   Chr8 : 58,789,081
0.000 0.999 0.000
rs7826834 lBF = 0.00116616   Chr8 : 62,401,962
0.000 0.999 0.000
rs279612 lBF = -0.0391292   Chr8 : 122,706,291
0.000 0.999 0.001
rs2705293 lBF = -0.0399492   Chr8 : 138,918,945
0.001 0.999 0.000
rs13253111 lBF = -0.0521439   Chr8 : 28,061,974
0.001 0.999 0.000
rs2916733 lBF = -0.0629949   Chr8 : 6,323,278
0.001 0.999 0.000
rs7006687 lBF = -0.0965045   Chr8 : 18,233,582
0.000 0.999 0.000
rs73225862 lBF = 6.53187   Chr8 : 22,050,584
0.000 0.999 0.000
rs10105606 lBF = 2.71178   Chr8 : 19,827,848
0.000 0.999 0.000
rs7841189 lBF = 1.77779   Chr8 : 19,845,376
0.000 0.999 0.000
rs10888073 lBF = 0.742031   Chr8 : 13,738,781
0.001 0.999 0.000
rs1540507 lBF = 0.0353765   Chr8 : 3,088,763
0.001 0.999 0.000
rs17077154 lBF = 0.0163422   Chr8 : 6,351,252
0.000 0.999 0.000
rs74804370 lBF = 0.0141725   Chr8 : 33,998,571
0.000 0.999 0.000
rs196889 lBF = -0.00893747   Chr8 : 24,734,677
0.000 0.999 0.000
rs10106540 lBF = -0.0881243   Chr8 : 134,461,851
0.001 0.999 0.000
rs10505477 lBF = 58.5637   Chr8 : 128,407,443
0.001 0.999 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0112
log Bayes Factor = 98.8923
contains 7 variants
0.4262
Cluster X0335
log Bayes Factor = 12.3689
contains 1 variants
0.3403
Cluster X0186
log Bayes Factor = 35.9761
contains 2 variants
0.1776
Cluster X0338
log Bayes Factor = 26.5485
contains 1 variants
0.0650
Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0060
log Bayes Factor = 242.413
contains 5 variants
0.7912
Cluster X0209
log Bayes Factor = 214.798
contains 8 variants
0.6865
Cluster X0321
log Bayes Factor = 162.562
contains 1 variants
0.6054
Cluster X0100
log Bayes Factor = 730.252
contains 26 variants
0.5951
Cluster X0083
log Bayes Factor = 351.917
contains 13 variants
0.5806
Cluster X0123
log Bayes Factor = 382.779
contains 14 variants
0.5785
Cluster X0084
log Bayes Factor = 433.078
contains 21 variants
0.5715
Cluster X0079
log Bayes Factor = 413.803
contains 22 variants
0.5668
Cluster X0326
log Bayes Factor = 112.92
contains 5 variants
0.5520
Cluster X0080
log Bayes Factor = 455.123
contains 21 variants
0.5518
Cluster X0250
log Bayes Factor = 43.399
contains 4 variants
0.5517
Cluster X0064
log Bayes Factor = 166.06
contains 10 variants
0.5488
Cluster X0141
log Bayes Factor = 742.063
contains 30 variants
0.5243
Cluster X0271
log Bayes Factor = 256.743
contains 10 variants
0.5140
Cluster X0146
log Bayes Factor = 686.343
contains 22 variants
0.5140
Cluster X0261
log Bayes Factor = 420.614
contains 20 variants
0.5140
Cluster X0277
log Bayes Factor = 726.213
contains 23 variants
0.5140
Cluster X0086
log Bayes Factor = 131.002
contains 8 variants
0.5140
Cluster X0087
log Bayes Factor = 894.58
contains 26 variants
0.5140
Cluster X0024
log Bayes Factor = 309.44
contains 13 variants
0.5140
Cluster X0057
log Bayes Factor = 439.35
contains 16 variants
0.5140
Cluster X0171
log Bayes Factor = 291.293
contains 14 variants
0.5140
Cluster X0140
log Bayes Factor = 164.536
contains 8 variants
0.5140
Cluster X0188
log Bayes Factor = 222.629
contains 14 variants
0.5140
Cluster X0072
log Bayes Factor = 1189.98
contains 37 variants
0.5140
Cluster X0170
log Bayes Factor = 264.081
contains 11 variants
0.5140
Cluster X0222
log Bayes Factor = 431.582
contains 17 variants
0.5140
Cluster X0177
log Bayes Factor = 254.872
contains 10 variants
0.5139
Cluster X0122
log Bayes Factor = 219.114
contains 9 variants
0.5139
Cluster X0094
log Bayes Factor = 562.956
contains 18 variants
0.5139
Cluster X0044
log Bayes Factor = 1165.44
contains 34 variants
0.5139
Cluster X0032
log Bayes Factor = 255.737
contains 12 variants
0.5139
Cluster X0091
log Bayes Factor = 303.64
contains 12 variants
0.5139
Cluster X0049
log Bayes Factor = 597.061
contains 18 variants
0.5138
Cluster X0075
log Bayes Factor = 431.344
contains 16 variants
0.5138
Cluster X0280
log Bayes Factor = 86.0876
contains 1 variants
0.5138
Cluster X0085
log Bayes Factor = 138.902
contains 6 variants
0.5138
Cluster X0257
log Bayes Factor = 281.184
contains 10 variants
0.5138
Cluster X0232
log Bayes Factor = 695.273
contains 23 variants
0.5138
Cluster X0073
log Bayes Factor = 785.614
contains 25 variants
0.5137
Cluster X0045
log Bayes Factor = 446.264
contains 16 variants
0.5137
Cluster X0055
log Bayes Factor = 274.911
contains 10 variants
0.5137
Cluster X0043
log Bayes Factor = 517.108
contains 20 variants
0.5137
Cluster X0020
log Bayes Factor = 557.721
contains 18 variants
0.5136
Cluster X0093
log Bayes Factor = 289.878
contains 10 variants
0.5136
Cluster X0109
log Bayes Factor = 257.685
contains 11 variants
0.5135
Cluster X0224
log Bayes Factor = 278.692
contains 11 variants
0.5135
Cluster X0197
log Bayes Factor = 158.582
contains 8 variants
0.5134
Cluster X0051
log Bayes Factor = 376.793
contains 14 variants
0.5134
Cluster X0145
log Bayes Factor = 274.587
contains 11 variants
0.5134
Cluster X0258
log Bayes Factor = 104.851
contains 6 variants
0.5133
Cluster X0205
log Bayes Factor = 674.183
contains 18 variants
0.5132
Cluster X0098
log Bayes Factor = 246.226
contains 8 variants
0.5131
Cluster X0227
log Bayes Factor = 249.287
contains 11 variants
0.5131
Cluster X0007
log Bayes Factor = 107.567
contains 7 variants
0.5130
Cluster X0150
log Bayes Factor = 861.091
contains 26 variants
0.5128
Cluster X0166
log Bayes Factor = 230.746
contains 8 variants
0.5128
Cluster X0039
log Bayes Factor = 463.231
contains 17 variants
0.5127
Cluster X0246
log Bayes Factor = 121.08
contains 5 variants
0.5127
Cluster X0124
log Bayes Factor = 336.468
contains 13 variants
0.5126
Cluster X0192
log Bayes Factor = 402.511
contains 14 variants
0.5126
Cluster X0153
log Bayes Factor = 328.394
contains 11 variants
0.5126
Cluster X0203
log Bayes Factor = 363.522
contains 11 variants
0.5126
Cluster X0042
log Bayes Factor = 307.243
contains 12 variants
0.5125
Cluster X0164
log Bayes Factor = 463.793
contains 16 variants
0.5124
Cluster X0174
log Bayes Factor = 214.209
contains 8 variants
0.5123
Cluster X0003
log Bayes Factor = 195.6
contains 8 variants
0.5122
Cluster X0028
log Bayes Factor = 120.445
contains 7 variants
0.5119
Cluster X0059
log Bayes Factor = 922.497
contains 26 variants
0.5119
Cluster X0161
log Bayes Factor = 609.219
contains 20 variants
0.5115
Cluster X0220
log Bayes Factor = 142.284
contains 7 variants
0.5112
Cluster X0143
log Bayes Factor = 179.808
contains 8 variants
0.5109
Cluster X0249
log Bayes Factor = 244.457
contains 11 variants
0.5102
Cluster X0284
log Bayes Factor = 192.532
contains 9 variants
0.5100
Cluster X0155
log Bayes Factor = 348.568
contains 12 variants
0.5096
Cluster X0078
log Bayes Factor = 203.49
contains 11 variants
0.5095
Cluster X0240
log Bayes Factor = 104.862
contains 6 variants
0.5088
Cluster X0026
log Bayes Factor = 232.119
contains 9 variants
0.5088
Cluster X0077
log Bayes Factor = 571.533
contains 17 variants
0.5086
Cluster X0053
log Bayes Factor = 218.825
contains 12 variants
0.5081
Cluster X0182
log Bayes Factor = 91.4459
contains 4 variants
0.5080
Cluster X0005
log Bayes Factor = 282.915
contains 11 variants
0.5070
Cluster X0139
log Bayes Factor = 304.555
contains 10 variants
0.5064
Cluster X0069
log Bayes Factor = 519.392
contains 20 variants
0.5055
Cluster X0181
log Bayes Factor = 141.396
contains 6 variants
0.5054
Cluster X0201
log Bayes Factor = 368.049
contains 13 variants
0.5054
Cluster X0074
log Bayes Factor = 353.38
contains 15 variants
0.5054
Cluster X0106
log Bayes Factor = 980.916
contains 30 variants
0.5052
Cluster X0129
log Bayes Factor = 195.809
contains 7 variants
0.5052
Cluster X0253
log Bayes Factor = 331.491
contains 13 variants
0.5042
Cluster X0221
log Bayes Factor = 149.378
contains 10 variants
0.5040
Cluster X0088
log Bayes Factor = 243.609
contains 9 variants
0.5035
Cluster X0256
log Bayes Factor = 211.588
contains 9 variants
0.5032
Cluster X0111
log Bayes Factor = 403.183
contains 18 variants
0.5032
Cluster X0052
log Bayes Factor = 654.387
contains 25 variants
0.5028
Cluster X0165
log Bayes Factor = 303.727
contains 12 variants
0.5018
Cluster X0210
log Bayes Factor = 426.159
contains 17 variants
0.5003
Cluster X0290
log Bayes Factor = 333.908
contains 13 variants
0.4982
Cluster X0110
log Bayes Factor = 721.325
contains 13 variants
0.4963
Cluster X0243
log Bayes Factor = 104.974
contains 6 variants
0.4958
Cluster X0037
log Bayes Factor = 171.712
contains 6 variants
0.4950
Cluster X0237
log Bayes Factor = 123.902
contains 6 variants
0.4947
Cluster X0082
log Bayes Factor = 496.905
contains 17 variants
0.4945
Cluster X0189
log Bayes Factor = 149.681
contains 5 variants
0.4942
Cluster X0102
log Bayes Factor = 99.5678
contains 5 variants
0.4939
Cluster X0142
log Bayes Factor = 295.63
contains 12 variants
0.4937
Cluster X0180
log Bayes Factor = 410.88
contains 15 variants
0.4932
Cluster X0176
log Bayes Factor = 407.797
contains 14 variants
0.4930
Cluster X0156
log Bayes Factor = 226.954
contains 9 variants
0.4908
Cluster X0012
log Bayes Factor = 112.432
contains 5 variants
0.4900
Cluster X0212
log Bayes Factor = 300.777
contains 10 variants
0.4898
Cluster X0040
log Bayes Factor = 542.747
contains 16 variants
0.4891
Cluster X0226
log Bayes Factor = 145.726
contains 8 variants
0.4890
Cluster X0021
log Bayes Factor = 338.631
contains 13 variants
0.4883
Cluster X0167
log Bayes Factor = 136.48
contains 6 variants
0.4878
Cluster X0248
log Bayes Factor = 254.854
contains 10 variants
0.4868
Cluster X0208
log Bayes Factor = 40.6733
contains 2 variants
0.4848
Cluster X0071
log Bayes Factor = 131.269
contains 6 variants
0.4844
Cluster X0214
log Bayes Factor = 186.582
contains 8 variants
0.4840
Cluster X0019
log Bayes Factor = 372.36
contains 16 variants
0.4838
Cluster X0231
log Bayes Factor = 82.3185
contains 5 variants
0.4829
Cluster X0293
log Bayes Factor = 169.051
contains 7 variants
0.4822
Cluster X0041
log Bayes Factor = 306.192
contains 14 variants
0.4773
Cluster X0275
log Bayes Factor = 219.726
contains 10 variants
0.4763
Cluster X0238
log Bayes Factor = 97.9307
contains 4 variants
0.4761
Cluster X0046
log Bayes Factor = 387.972
contains 16 variants
0.4759
Cluster X0081
log Bayes Factor = 278.568
contains 10 variants
0.4751
Cluster X0178
log Bayes Factor = 225.6
contains 9 variants
0.4750
Cluster X0070
log Bayes Factor = 421.182
contains 15 variants
0.4748
Cluster X0274
log Bayes Factor = 454.783
contains 18 variants
0.4744
Cluster X0119
log Bayes Factor = 114.358
contains 6 variants
0.4712
Cluster X0089
log Bayes Factor = 308.747
contains 13 variants
0.4710
Cluster X0213
log Bayes Factor = 405.918
contains 15 variants
0.4681
Cluster X0133
log Bayes Factor = 224.204
contains 11 variants
0.4668
Cluster X0327
log Bayes Factor = 118.248
contains 3 variants
0.4663
Cluster X0058
log Bayes Factor = 183.199
contains 8 variants
0.4654
Cluster X0194
log Bayes Factor = 189.9
contains 5 variants
0.4644
Cluster X0297
log Bayes Factor = 63.8292
contains 4 variants
0.4613
Cluster X0218
log Bayes Factor = 425.579
contains 18 variants
0.4503
Cluster X0157
log Bayes Factor = 172.957
contains 8 variants
0.4494
Cluster X0029
log Bayes Factor = 709.102
contains 23 variants
0.4492
Cluster X0134
log Bayes Factor = 151.731
contains 8 variants
0.4322
Cluster X0050
log Bayes Factor = 397.79
contains 16 variants
0.4316
Cluster X0038
log Bayes Factor = 31.1234
contains 2 variants
0.4238
Cluster X0337
log Bayes Factor = 84.9395
contains 2 variants
0.4226
Cluster X0339
log Bayes Factor = 56.078
contains 2 variants
0.4225
Cluster X0268
log Bayes Factor = 213.591
contains 8 variants
0.4220
Cluster X0118
log Bayes Factor = 91.1908
contains 5 variants
0.4187
Cluster X0033
log Bayes Factor = 379.444
contains 13 variants
0.4071
Cluster X0163
log Bayes Factor = 122.554
contains 6 variants
0.4071
Cluster X0014
log Bayes Factor = 131.677
contains 6 variants
0.4068
Cluster X0047
log Bayes Factor = 378.621
contains 14 variants
0.4045
Cluster X0294
log Bayes Factor = 25.2869
contains 2 variants
0.4045
Cluster X0076
log Bayes Factor = 310.928
contains 15 variants
0.4027
Cluster X0001
log Bayes Factor = 167.541
contains 7 variants
0.3962
Cluster X0137
log Bayes Factor = 120.748
contains 4 variants
0.3932
Cluster X0229
log Bayes Factor = 347.165
contains 13 variants
0.3829
Cluster X0054
log Bayes Factor = 197.338
contains 9 variants
0.3796
Cluster X0015
log Bayes Factor = 356.23
contains 15 variants
0.3787
Cluster X0067
log Bayes Factor = 179.381
contains 8 variants
0.3695
Cluster X0132
log Bayes Factor = 267.393
contains 11 variants
0.3673
Cluster X0126
log Bayes Factor = 384.432
contains 15 variants
0.3657
Cluster X0259
log Bayes Factor = 246.237
contains 11 variants
0.3603
Cluster X0107
log Bayes Factor = 151.016
contains 1 variants
0.3581
Cluster X0191
log Bayes Factor = 163.555
contains 8 variants
0.3561
Cluster X0330
log Bayes Factor = 183.455
contains 2 variants
0.3492
Cluster X0287
log Bayes Factor = 33.3095
contains 4 variants
0.3485
Cluster X0263
log Bayes Factor = 240.36
contains 13 variants
0.3428
Cluster X0264
log Bayes Factor = 205.833
contains 10 variants
0.3374
Cluster X0307
log Bayes Factor = 826.86
contains 2 variants
0.3344
Cluster X0148
log Bayes Factor = 315.237
contains 11 variants
0.3254
Cluster X0204
log Bayes Factor = 169.796
contains 8 variants
0.3165
Cluster X0030
log Bayes Factor = 216.364
contains 9 variants
0.3157
Cluster X0184
log Bayes Factor = 188.416
contains 8 variants
0.3133
Cluster X0152
log Bayes Factor = 331.156
contains 10 variants
0.3126
Cluster X0063
log Bayes Factor = 107.557
contains 5 variants
0.3043
Cluster X0018
log Bayes Factor = 430.611
contains 18 variants
0.3025
Cluster X0236
log Bayes Factor = 83.9265
contains 3 variants
0.3012
Cluster X0154
log Bayes Factor = 282.084
contains 12 variants
0.2986
Cluster X0048
log Bayes Factor = 358.819
contains 19 variants
0.2834
Cluster X0320
log Bayes Factor = 110.964
contains 6 variants
0.2829
Cluster X0159
log Bayes Factor = 152.327
contains 7 variants
0.2788
Cluster X0283
log Bayes Factor = 162.98
contains 9 variants
0.2696
Cluster X0138
log Bayes Factor = 43.7891
contains 4 variants
0.2638
Cluster X0162
log Bayes Factor = 144.479
contains 9 variants
0.2619
Cluster X0068
log Bayes Factor = 127.774
contains 6 variants
0.2608
Cluster X0322
log Bayes Factor = 70.0115
contains 3 variants
0.2545
Cluster X0117
log Bayes Factor = 453.246
contains 21 variants
0.2483
Cluster X0276
log Bayes Factor = 187.108
contains 9 variants
0.2472
Cluster X0095
log Bayes Factor = 179.348
contains 8 variants
0.2339
Cluster X0120
log Bayes Factor = 79.6695
contains 4 variants
0.2176
Cluster X0061
log Bayes Factor = 293.105
contains 15 variants
0.2175
Cluster X0332
log Bayes Factor = 65.2374
contains 3 variants
0.2126
Cluster X0324
log Bayes Factor = 32.1341
contains 1 variants
0.1990
Cluster X0121
log Bayes Factor = 131.08
contains 9 variants
0.1933
Cluster X0131
log Bayes Factor = 143.942
contains 8 variants
0.1913
Cluster X0185
log Bayes Factor = 84.7127
contains 6 variants
0.1715
Cluster X0013
log Bayes Factor = 548.265
contains 23 variants
0.1488
Cluster X0169
log Bayes Factor = 331.98
contains 16 variants
0.1050
Cluster X0114
log Bayes Factor = 510.917
contains 25 variants
0.0703
Cluster X0262
log Bayes Factor = 269.713
contains 9 variants
0.0532
 
 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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