TreeWAS – Variant ID: rs115849089

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.009	0.991
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.013	0.987
I21 Acute myocardial infarction	0.000	0.013	0.987
I25.2 Old myocardial infarction	0.000	0.016	0.984
I20.9 Angina pectoris, unspecified	0.000	0.017	0.983
I24 Other acute ischaemic heart diseases	0.000	0.023	0.977
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.039	0.961
I21.9 Acute myocardial infarction, unspecified	0.000	0.060	0.940
I20.0 Unstable angina	0.000	0.060	0.940
I22 Subsequent myocardial infarction	0.000	0.067	0.933
I24.8 Other forms of acute ischaemic heart disease	0.000	0.067	0.933
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.099	0.901
E78.0 Pure hypercholesterolaemia	0.000	0.124	0.876
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.131	0.869
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.136	0.864
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.151	0.849
E78.5 Hyperlipidaemia, unspecified	0.000	0.158	0.842
I25.4 Coronary artery aneurysm	0.000	0.193	0.807
E78.2 Mixed hyperlipidaemia	0.000	0.203	0.797
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.246	0.754
E78.1 Pure hyperglyceridaemia	0.000	0.253	0.747
I23 Certain current complications following acute myocardial infarction	0.000	0.266	0.734
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.290	0.710
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.292	0.707
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.311	0.689
E78.4 Other hyperlipidaemia	0.000	0.331	0.669
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.333	0.667
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.340	0.660
I22.8 Subsequent myocardial infarction of other sites	0.000	0.343	0.657
I24.1 Dressler's syndrome	0.000	0.375	0.625
E78.6 Lipoprotein deficiency	0.000	0.380	0.620
E78.3 Hyperchylomicronaemia	0.000	0.380	0.620
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.393	0.606
E78.8 Other disorders of lipoprotein metabolism	0.000	0.394	0.606
I25.5 Ischaemic cardiomyopathy	0.000	0.404	0.596
I23.8 Other current complications following acute myocardial infarction	0.000	0.456	0.544
I20.1 Angina pectoris with documented spasm	0.000	0.472	0.528
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.473	0.527
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.473	0.527
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.473	0.527
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.473	0.527
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.473	0.527
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.473	0.527
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.473	0.527
I25.3 Aneurysm of heart	0.000	0.496	0.504
I21.4 Acute subendocardial myocardial infarction	0.000	0.514	0.486
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.616	0.384
I20.8 Other forms of angina pectoris	0.000	0.700	0.300
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.807	0.193
I77 Other disorders of arteries and arterioles	0.000	0.808	0.192
I71 Aortic aneurysm and dissection	0.000	0.815	0.185
I77.1 Stricture of artery	0.000	0.821	0.179
I77.6 Arteritis, unspecified	0.000	0.824	0.176
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.830	0.170
I72 Other aneurysm	0.000	0.830	0.170
I70 Atherosclerosis	0.000	0.834	0.166
Chapter IX Diseases of the circulatory system	0.000	0.841	0.159
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.841	0.159
I77.8 Other specified disorders of arteries and arterioles	0.000	0.845	0.155
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.846	0.154
I72.4 Aneurysm of artery of lower extremity	0.000	0.847	0.153
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.847	0.153
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.848	0.152
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.850	0.150
I71.0 Dissection of aorta [any part]	0.000	0.855	0.145
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.855	0.145
I72.8 Aneurysm of other specified arteries	0.000	0.857	0.142
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.859	0.141
I77.5 Necrosis of artery	0.000	0.862	0.138
I77.4 Coeliac artery compression syndrome	0.000	0.862	0.138
I77.3 Arterial fibromuscular dysplasia	0.000	0.862	0.138
I77.2 Rupture of artery	0.000	0.862	0.138
I72.3 Aneurysm of iliac artery	0.000	0.867	0.133
I77.0 Arteriovenous fistula, acquired	0.000	0.867	0.133
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.867	0.133
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.867	0.133
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.867	0.133
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.867	0.133
I70.0 Atherosclerosis of aorta	0.000	0.869	0.131
I78 Diseases of capillaries	0.000	0.872	0.128
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.878	0.122
I79.1 Aortitis in diseases classified elsewhere	0.000	0.878	0.122
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.878	0.122
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.878	0.122
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.878	0.122
I72.1 Aneurysm of artery of upper extremity	0.000	0.878	0.122
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.878	0.122
I72.2 Aneurysm of renal artery	0.000	0.878	0.122
I74 Arterial embolism and thrombosis	0.000	0.878	0.122
I72.9 Aneurysm of unspecified site	0.000	0.879	0.121
I70.9 Generalised and unspecified atherosclerosis	0.000	0.881	0.119
I70.8 Atherosclerosis of other arteries	0.000	0.881	0.119
I70.1 Atherosclerosis of renal artery	0.000	0.881	0.119
I00-I02 Acute rheumatic fever	0.000	0.886	0.114
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.894	0.106
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.899	0.101
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.899	0.101
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.902	0.098
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.903	0.097
E70-E90 Metabolic disorders	0.000	0.905	0.095
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.906	0.094
I78.9 Disease of capillaries, unspecified	0.000	0.908	0.092
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.910	0.090
I74.8 Embolism and thrombosis of other arteries	0.000	0.912	0.088
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.912	0.088
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.912	0.088
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.912	0.088
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.914	0.086
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.914	0.086
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.914	0.086
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.914	0.086
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.914	0.086
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.914	0.086
I74.5 Embolism and thrombosis of iliac artery	0.000	0.918	0.082
I78.8 Other diseases of capillaries	0.000	0.918	0.082
I02 Rheumatic chorea	0.000	0.918	0.082
I01 Rheumatic fever with heart involvement	0.000	0.918	0.082
I00 Rheumatic fever without mention of heart involvement	0.000	0.918	0.082
E83.1 Disorders of iron metabolism	0.000	0.918	0.082
E83 Disorders of mineral metabolism	0.000	0.919	0.081
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.921	0.079
I78.1 Naevus, nonneoplastic	0.000	0.921	0.079
I97.1 Other functional disturbances following cardiac surgery	0.000	0.922	0.078
E74 Other disorders of carbohydrate metabolism	0.000	0.923	0.077
I72.0 Aneurysm of carotid artery	0.001	0.925	0.075
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.925	0.075
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.926	0.074
E73 Lactose intolerance	0.000	0.927	0.072
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.928	0.072
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.928	0.072
E84 Cystic fibrosis	0.000	0.931	0.069
E79 Disorders of purine and pyrimidine metabolism	0.000	0.931	0.069
E77 Disorders of glycoprotein metabolism	0.000	0.931	0.069
E76 Disorders of glycosaminoglycan metabolism	0.000	0.931	0.069
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.931	0.069
E72 Other disorders of amino-acid metabolism	0.000	0.931	0.069
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.931	0.069
E70 Disorders of aromatic amino-acid metabolism	0.000	0.931	0.069
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.931	0.069
E88 Other metabolic disorders	0.000	0.932	0.068
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.935	0.065
I97.0 Postcardiotomy syndrome	0.000	0.935	0.065
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.936	0.063
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.936	0.064
E85 Amyloidosis	0.000	0.936	0.063
I99 Other and unspecified disorders of circulatory system	0.000	0.939	0.061
E86 Volume depletion	0.000	0.939	0.061
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.941	0.059
I01.8 Other acute rheumatic heart disease	0.000	0.941	0.059
I01.2 Acute rheumatic myocarditis	0.000	0.941	0.059
I01.1 Acute rheumatic endocarditis	0.000	0.941	0.059
I01.0 Acute rheumatic pericarditis	0.000	0.941	0.059
I02.9 Rheumatic chorea without heart involvement	0.000	0.941	0.059
I02.0 Rheumatic chorea with heart involvement	0.000	0.941	0.059
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.942	0.058
E83.8 Other disorders of mineral metabolism	0.000	0.942	0.058
E83.2 Disorders of zinc metabolism	0.000	0.942	0.058
E83.0 Disorders of copper metabolism	0.000	0.942	0.058
I05-I09 Chronic rheumatic heart diseases	0.000	0.943	0.057
I73 Other peripheral vascular diseases	0.000	0.943	0.057
E73.9 Lactose intolerance, unspecified	0.000	0.944	0.056
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.944	0.055
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.944	0.055
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.944	0.055
E74.2 Disorders of galactose metabolism	0.000	0.944	0.055
E74.1 Disorders of fructose metabolism	0.000	0.944	0.055
E74.0 Glycogen storage disease	0.000	0.944	0.055
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.944	0.055
E83.4 Disorders of magnesium metabolism	0.000	0.946	0.054
E73.8 Other lactose intolerance	0.000	0.948	0.052
E73.1 Secondary lactase deficiency	0.000	0.948	0.052
E73.0 Congenital lactase deficiency	0.000	0.948	0.052
E88.2 Lipomatosis, not elsewhere classified	0.000	0.950	0.050
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.950	0.050
E85.4 Organ-limited amyloidosis	0.000	0.950	0.050
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.950	0.049
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.950	0.049
E70.3 Albinism	0.000	0.950	0.049
E70.2 Disorders of tyrosine metabolism	0.000	0.950	0.049
E70.1 Other hyperphenylalaninaemias	0.000	0.950	0.049
E70.0 Classical phenylketonuria	0.000	0.950	0.049
E71.3 Disorders of fatty-acid metabolism	0.000	0.950	0.049
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.950	0.049
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.950	0.049
E71.0 Maple-syrup-urine disease	0.000	0.950	0.049
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.950	0.049
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.950	0.049
E72.5 Disorders of glycine metabolism	0.000	0.950	0.049
E72.4 Disorders of ornithine metabolism	0.000	0.950	0.049
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.950	0.049
E72.2 Disorders of urea cycle metabolism	0.000	0.950	0.049
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.950	0.049
E72.0 Disorders of amino-acid transport	0.000	0.950	0.049
E75.6 Lipid storage disorder, unspecified	0.000	0.950	0.049
E75.5 Other lipid storage disorders	0.000	0.950	0.049
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.950	0.049
E75.3 Sphingolipidosis, unspecified	0.000	0.950	0.049
E75.2 Other sphingolipidosis	0.000	0.950	0.049
E75.1 Other gangliosidosis	0.000	0.950	0.049
E75.0 GM2 gangliosidosis	0.000	0.950	0.049
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.950	0.049
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.950	0.049
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.950	0.049
E76.2 Other mucopolysaccharidoses	0.000	0.950	0.049
E76.1 Mucopolysaccharidosis, type II	0.000	0.950	0.049
E76.0 Mucopolysaccharidosis, type I	0.000	0.950	0.049
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.950	0.049
E77.8 Other disorders of glycoprotein metabolism	0.000	0.950	0.049
E77.1 Defects in glycoprotein degradation	0.000	0.950	0.049
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.950	0.049
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.950	0.049
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.950	0.049
E79.1 Lesch-Nyhan syndrome	0.000	0.950	0.049
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.950	0.049
E84.9 Cystic fibrosis, unspecified	0.000	0.950	0.049
E84.8 Cystic fibrosis with other manifestations	0.000	0.950	0.049
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.950	0.049
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.950	0.049
E88.9 Metabolic disorder, unspecified	0.000	0.951	0.049
E88.8 Other specified metabolic disorders	0.000	0.951	0.049
E88.3 Tumour lysis syndrome	0.000	0.951	0.049
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.951	0.049
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.953	0.047
E85.8 Other amyloidosis	0.000	0.954	0.046
E85.3 Secondary systemic amyloidosis	0.000	0.954	0.046
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.954	0.046
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.954	0.046
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.954	0.046
I28 Other diseases of pulmonary vessels	0.001	0.956	0.043
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.959	0.041
I06 Rheumatic aortic valve diseases	0.000	0.959	0.041
I73.8 Other specified peripheral vascular diseases	0.000	0.959	0.041
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.960	0.040
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.960	0.040
I98.0 Cardiovascular syphilis	0.000	0.960	0.040
I09 Other rheumatic heart diseases	0.000	0.961	0.038
E83.3 Disorders of phosphorus metabolism	0.000	0.963	0.036
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.964	0.036
E80.5 Crigler-Najjar syndrome	0.000	0.964	0.036
E80.3 Defects of catalase and peroxydase	0.000	0.964	0.036
E80.2 Other porphyria	0.000	0.964	0.036
E80.1 Porphyria cutanea tarda	0.000	0.964	0.036
E80.0 Hereditary erythropoietic porphyria	0.000	0.964	0.036
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.965	0.035
E85.9 Amyloidosis, unspecified	0.000	0.966	0.034
I27 Other pulmonary heart diseases	0.000	0.966	0.033
K08.3 Retained dental root	0.000	0.967	0.033
I10-I15 Hypertensive diseases	0.000	0.968	0.032
I08 Multiple valve diseases	0.000	0.968	0.032
I05 Rheumatic mitral valve diseases	0.000	0.968	0.032
I73.9 Peripheral vascular disease, unspecified	0.000	0.968	0.032
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.968	0.031
I28.1 Aneurysm of pulmonary artery	0.001	0.968	0.031
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.968	0.031
E80.6 Other disorders of bilirubin metabolism	0.000	0.969	0.031
I07 Rheumatic tricuspid valve diseases	0.000	0.969	0.031
I26 Pulmonary embolism	0.004	0.969	0.026
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.970	0.030
K08 Other disorders of teeth and supporting structures	0.000	0.970	0.030
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.970	0.029
I06.8 Other rheumatic aortic valve diseases	0.000	0.970	0.029
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.970	0.029
I06.1 Rheumatic aortic insufficiency	0.000	0.970	0.029
I06.0 Rheumatic aortic stenosis	0.000	0.970	0.029
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.971	0.029
I28.8 Other specified diseases of pulmonary vessels	0.001	0.971	0.029
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.972	0.028
I09.8 Other specified rheumatic heart diseases	0.000	0.972	0.028
I09.2 Chronic rheumatic pericarditis	0.000	0.972	0.028
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.972	0.028
I09.0 Rheumatic myocarditis	0.000	0.972	0.028
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.974	0.026
E80.4 Gilbert's syndrome	0.000	0.974	0.026
I09.9 Rheumatic heart disease, unspecified	0.000	0.975	0.025
I08.8 Other multiple valve diseases	0.000	0.975	0.025
I05.1 Rheumatic mitral insufficiency	0.000	0.975	0.025
I27.1 Kyphoscoliotic heart disease	0.000	0.975	0.024
I27.9 Pulmonary heart disease, unspecified	0.000	0.976	0.024
I27.8 Other specified pulmonary heart diseases	0.000	0.976	0.024
I11 Hypertensive heart disease	0.000	0.976	0.024
I05.2 Mitral stenosis with insufficiency	0.000	0.976	0.024
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.977	0.023
I13 Hypertensive heart and renal disease	0.000	0.977	0.023
I08.9 Multiple valve disease, unspecified	0.000	0.977	0.023
I05.8 Other mitral valve diseases	0.000	0.977	0.023
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.977	0.023
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.977	0.023
I07.9 Tricuspid valve disease, unspecified	0.000	0.978	0.022
I07.8 Other tricuspid valve diseases	0.000	0.978	0.022
I07.2 Tricuspid stenosis with insufficiency	0.000	0.978	0.022
I07.0 Tricuspid stenosis	0.000	0.978	0.022
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.003	0.978	0.019
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.978	0.022
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.978	0.022
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.979	0.021
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.979	0.021
E89.5 Postprocedural testicular hypofunction	0.000	0.979	0.021
E89.4 Postprocedural ovarian failure	0.000	0.979	0.021
E89.1 Postprocedural hypoinsulinaemia	0.000	0.979	0.021
I27.0 Primary pulmonary hypertension	0.000	0.980	0.020
I15 Secondary hypertension	0.000	0.980	0.020
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.980	0.020
I27.2 Other secondary pulmonary hypertension	0.000	0.980	0.020
E89.3 Postprocedural hypopituitarism	0.000	0.981	0.019
E89.2 Postprocedural hypoparathyroidism	0.000	0.981	0.019
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.981	0.019
I08.0 Disorders of both mitral and aortic valves	0.000	0.981	0.019
I05.0 Mitral stenosis	0.000	0.981	0.018
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.981	0.018
I95 Hypotension	0.000	0.982	0.018
E83.5 Disorders of calcium metabolism	0.000	0.983	0.017
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.983	0.017
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.983	0.017
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.983	0.017
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.983	0.017
I05.9 Mitral valve disease, unspecified	0.000	0.984	0.015
I15.1 Hypertension secondary to other renal disorders	0.000	0.985	0.015
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.985	0.014
I15.8 Other secondary hypertension	0.000	0.985	0.014
I15.2 Hypertension secondary to endocrine disorders	0.000	0.985	0.014
I15.0 Renovascular hypertension	0.000	0.985	0.014
I95.8 Other hypotension	0.000	0.986	0.014
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.988	0.012
I07.1 Tricuspid insufficiency	0.000	0.988	0.012
Z13.6 Special screening examination for cardiovascular disorders	0.011	0.989	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.989	0.011
I95.0 Idiopathic hypotension	0.000	0.989	0.011
I15.9 Seconday hypertension, unspecified	0.001	0.989	0.010
E11.1 With ketoacidosis	0.000	0.990	0.010
E61.1 Iron deficiency	0.000	0.990	0.010
E40-E46 Malnutrition	0.000	0.990	0.010
I73.0 Raynaud's syndrome	0.000	0.990	0.010
R16.1 Splenomegaly, not elsewhere classified	0.010	0.990	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.990	0.010
E50-E64 Other nutritional deficiencies	0.000	0.990	0.010
E61 Deficiency of other nutrient elements	0.000	0.990	0.010
E11.0 With coma	0.000	0.990	0.010
E11.4 With neurological complications	0.000	0.990	0.010
E11.2 With renal complications	0.000	0.991	0.009
E10-E14 Diabetes mellitus	0.000	0.991	0.009
E11.3 With ophthalmic complications	0.000	0.991	0.009
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.991	0.009
E11.5 With peripheral circulatory complications	0.000	0.991	0.009
I12 Hypertensive renal disease	0.000	0.991	0.009
E46 Unspecified protein-energy malnutrition	0.000	0.991	0.009
E11.6 With other specified complications	0.000	0.991	0.009
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.991	0.009
E16 Other disorders of pancreatic internal secretion	0.000	0.991	0.008
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.008	0.992	0.000
E11.7 With multiple complications	0.000	0.992	0.008
I95.9 Hypotension, unspecified	0.000	0.992	0.008
E11.8 With unspecified complications	0.000	0.992	0.008
I95.1 Orthostatic hypotension	0.000	0.992	0.008
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.992	0.008
E45 Retarded development following protein-energy malnutrition	0.000	0.992	0.008
E43 Unspecified severe protein-energy malnutrition	0.000	0.992	0.008
E42 Marasmic kwashiorkor	0.000	0.992	0.008
E41 Nutritional marasmus	0.000	0.992	0.008
E40 Kwashiorkor	0.000	0.992	0.008
E15 Nondiabetic hypoglycaemic coma	0.000	0.992	0.007
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.992	0.007
E63 Other nutritional deficiencies	0.000	0.992	0.007
E56 Other vitamin deficiencies	0.000	0.992	0.007
E51 Thiamine deficiency	0.000	0.992	0.007
E50 Vitamin A deficiency	0.000	0.992	0.007
E60 Dietary zinc deficiency	0.000	0.992	0.007
E59 Dietary selenium deficiency	0.000	0.992	0.007
E58 Dietary calcium deficiency	0.000	0.992	0.007
E54 Ascorbic acid deficiency	0.000	0.992	0.007
E52 Niacin deficiency [pellagra]	0.000	0.992	0.007
E61.9 Deficiency of nutrient element, unspecified	0.000	0.992	0.007
E61.8 Deficiency of other specified nutrient elements	0.000	0.992	0.007
E61.7 Deficiency of multiple nutrient elements	0.000	0.992	0.007
E61.6 Vanadium deficiency	0.000	0.992	0.007
E61.5 Molybdenum deficiency	0.000	0.992	0.007
E61.4 Chromium deficiency	0.000	0.992	0.007
E61.3 Manganese deficiency	0.000	0.992	0.007
E61.2 Magnesium deficiency	0.000	0.992	0.007
E61.0 Copper deficiency	0.000	0.992	0.007
E16.2 Hypoglycaemia, unspecified	0.000	0.993	0.007
E87.5 Hyperkalaemia	0.000	0.993	0.007
E65-E68 Obesity and other hyperalimentation	0.000	0.993	0.007
E11.9 Without complications	0.000	0.993	0.007
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.993	0.007
E12 Malnutrition-related diabetes mellitus	0.000	0.993	0.007
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.993	0.007
E87.3 Alkalosis	0.000	0.993	0.007
E16.1 Other hypoglycaemia	0.000	0.993	0.007
E89.0 Postprocedural hypothyroidism	0.000	0.993	0.006
I60-I69 Cerebrovascular diseases	0.000	0.993	0.007
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.994	0.006
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.994	0.006
E16.4 Abnormal secretion of gastrin	0.000	0.994	0.006
E16.3 Increased secretion of glucagon	0.000	0.994	0.006
E87.4 Mixed disorder of acid-base balance	0.000	0.994	0.006
E55 Vitamin D deficiency	0.000	0.994	0.006
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.994	0.006
T40.2 Other opioids	0.000	0.994	0.006
E65 Localised adiposity	0.000	0.994	0.006
E44.1 Mild protein-energy malnutrition	0.000	0.994	0.006
E44.0 Moderate protein-energy malnutrition	0.000	0.994	0.006
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.994	0.006
E50.9 Vitamin A deficiency, unspecified	0.000	0.994	0.005
E50.8 Other manifestations of vitamin A deficiency	0.000	0.994	0.005
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.994	0.005
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.994	0.005
E50.5 Vitamin A deficiency with night blindness	0.000	0.994	0.005
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.994	0.005
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.994	0.005
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.994	0.005
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.994	0.005
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.994	0.005
E51.9 Thiamine deficiency, unspecified	0.000	0.994	0.005
E51.8 Other manifestations of thiamine deficiency	0.000	0.994	0.005
E51.2 Wernicke's encephalopathy	0.000	0.994	0.005
E51.1 Beriberi	0.000	0.994	0.005
E56.9 Vitamin deficiency, unspecified	0.000	0.994	0.005
E56.8 Deficiency of other vitamins	0.000	0.994	0.005
E56.1 Deficiency of vitamin K	0.000	0.994	0.005
E56.0 Deficiency of vitamin E	0.000	0.994	0.005
E63.9 Nutritional deficiency, unspecified	0.000	0.994	0.005
E63.8 Other specified nutritional deficiencies	0.000	0.994	0.005
E63.1 Imbalance of constituents of food intake	0.000	0.994	0.005
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.994	0.005
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.994	0.005
E64.8 Sequelae of other nutritional deficiencies	0.000	0.994	0.005
E64.3 Sequelae of rickets	0.000	0.994	0.005
E64.2 Sequelae of vitamin C deficiency	0.000	0.994	0.005
E64.1 Sequelae of vitamin A deficiency	0.000	0.994	0.005
E64.0 Sequelae of protein-energy malnutrition	0.000	0.994	0.005
I95.2 Hypotension due to drugs	0.001	0.994	0.005
N39.4 Other specified urinary incontinence	0.000	0.995	0.005
N41.1 Chronic prostatitis	0.005	0.995	0.000
E13 Other specified diabetes mellitus	0.000	0.995	0.005
E67 Other hyperalimentation	0.000	0.995	0.005
E68 Sequelae of hyperalimentation	0.000	0.995	0.005
E12.9 Without complications	0.000	0.995	0.005
E12.8 With unspecified complications	0.000	0.995	0.005
E12.7 With multiple complications	0.000	0.995	0.005
E12.6 With other specified complications	0.000	0.995	0.005
E12.5 With peripheral circulatory complications	0.000	0.995	0.005
E12.4 With neurological complications	0.000	0.995	0.005
E12.3 With ophthalmic complications	0.000	0.995	0.005
E12.2 With renal complications	0.000	0.995	0.005
E12.1 With ketoacidosis	0.000	0.995	0.005
E12.0 With coma	0.000	0.995	0.005
M13.9 Arthritis, unspecified	0.000	0.995	0.005
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.995	0.005
I63 Cerebral infarction	0.000	0.995	0.005
E87.7 Fluid overload	0.000	0.995	0.005
I65.2 Occlusion and stenosis of carotid artery	0.000	0.995	0.005
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.995	0.005
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.995	0.005
E55.0 Rickets, active	0.000	0.995	0.005
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
I63.8 Other cerebral infarction	0.000	0.995	0.005
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.005	0.995	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.995	0.005
T40.4 Other synthetic narcotics	0.000	0.995	0.005
M13.98 Arthritis, unspecified (Other)	0.000	0.995	0.004
E87.0 Hyperosmolality and hypernatraemia	0.000	0.995	0.004
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.996	0.004
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.996	0.004
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.996	0.004
I65.1 Occlusion and stenosis of basilar artery	0.000	0.996	0.004
H83.0 Labyrinthitis	0.000	0.996	0.004
M13.94 Arthritis, unspecified (Hand)	0.000	0.996	0.004
B18.2 Chronic viral hepatitis C	0.000	0.996	0.004
E13.8 With unspecified complications	0.000	0.996	0.004
E13.7 With multiple complications	0.000	0.996	0.004
E13.6 With other specified complications	0.000	0.996	0.004
E13.5 With peripheral circulatory complications	0.000	0.996	0.004
E13.4 With neurological complications	0.000	0.996	0.004
E13.3 With ophthalmic complications	0.000	0.996	0.004
E13.2 With renal complications	0.000	0.996	0.004
E13.1 With ketoacidosis	0.000	0.996	0.004
E13.0 With coma	0.000	0.996	0.004
E28.3 Primary ovarian failure	0.004	0.996	0.000
E67.8 Other specified hyperalimentation	0.000	0.996	0.004
E67.3 Hypervitaminosis D	0.000	0.996	0.004
E67.2 Megavitamin-B6 syndrome	0.000	0.996	0.004
E67.1 Hypercarotenaemia	0.000	0.996	0.004
E67.0 Hypervitaminosis A	0.000	0.996	0.004
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.996	0.004
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.996	0.004
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.996	0.004
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
E28 Ovarian dysfunction	0.004	0.996	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
E14 Unspecified diabetes mellitus	0.000	0.996	0.004
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.996	0.004
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.996	0.004
T40.8 Lysergide [LSD]	0.000	0.996	0.004
T40.7 Cannabis (derivatives)	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations