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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6984045
log Bayes Factor = 7.25756
Chromosome 8   position 131,092,413  (GRCh37) Explore rs6984045 on Ensembl!
Variant rs6984045 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.995 0.005 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.993 0.007 0.000
M54 Dorsalgia
0.992 0.008 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.990 0.010 0.000
M35 Other systemic involvement of connective tissue
0.988 0.012 0.000
M35.3 Polymyalgia rheumatica
0.984 0.016 0.000
I50 Heart failure
0.982 0.018 0.000
I47 Paroxysmal tachycardia
0.980 0.020 0.000
M54.5 Low back pain
0.980 0.020 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.978 0.022 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.970 0.030 0.000
M54.59 Low back pain (Site unspecified)
0.961 0.039 0.000
I47.1 Supraventricular tachycardia
0.960 0.040 0.000
I50.1 Left ventricular failure
0.958 0.042 0.000
Chapter VI Diseases of the nervous system
0.956 0.044 0.000
L60-L75 Disorders of skin appendages
0.955 0.045 0.000
S90-S99 Injuries to the ankle and foot
0.953 0.047 0.000
I25.1 Atherosclerotic heart disease
0.947 0.053 0.000
Chapter VII Diseases of the eye and adnexa
0.946 0.054 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.945 0.055 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.943 0.057 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.934 0.066 0.000
M54.9 Dorsalgia, unspecified
0.932 0.068 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.927 0.073 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.924 0.076 0.000
Chapter VIII Diseases of the ear and mastoid process
0.917 0.083 0.000
I50.0 Congestive heart failure
0.916 0.084 0.000
M45-M49 Spondylopathies
0.914 0.086 0.000
Chapter V Mental and behavioural disorders
0.904 0.096 0.000
H53-H54 Visual disturbances and blindness
0.903 0.097 0.000
M80-M85 Disorders of bone density and structure
0.903 0.097 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.901 0.099 0.000
M25 Other joint disorders, not elsewhere classified
0.900 0.100 0.000
L72.1 Trichilemmal cyst
0.896 0.104 0.000
H90-H95 Other disorders of ear
0.892 0.108 0.000
M48 Other spondylopathies
0.883 0.117 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.880 0.120 0.000
Q60-Q64 Congenital malformations of the urinary system
0.880 0.120 0.000
E10-E14 Diabetes mellitus
0.877 0.123 0.000
H53 Visual disturbances
0.877 0.123 0.000
H53.2 Diplopia
0.875 0.125 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.868 0.132 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.868 0.132 0.000
M86-M90 Other osteopathies
0.866 0.133 0.000
L72.0 Epidermal cyst
0.863 0.137 0.000
G30-G32 Other degenerative diseases of the nervous system
0.862 0.138 0.000
G35 Multiple sclerosis
0.861 0.139 0.000
I25.2 Old myocardial infarction
0.856 0.144 0.000
I47.2 Ventricular tachycardia
0.853 0.147 0.000
M48.0 Spinal stenosis
0.853 0.147 0.000
S92 Fracture of foot, except ankle
0.852 0.148 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.844 0.156 0.000
I73 Other peripheral vascular diseases
0.844 0.156 0.000
E20-E35 Disorders of other endocrine glands
0.843 0.157 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.834 0.166 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.834 0.166 0.000
M91-M94 Chondropathies
0.833 0.167 0.000
I21 Acute myocardial infarction
0.832 0.168 0.000
M54.56 Low back pain (Lumbar region)
0.832 0.168 0.000
S60-S69 Injuries to the wrist and hand
0.829 0.171 0.000
E10 Insulin-dependent diabetes mellitus
0.829 0.171 0.000
M34 Systemic sclerosis
0.824 0.176 0.000
I35 Nonrheumatic aortic valve disorders
0.822 0.178 0.000
I24 Other acute ischaemic heart diseases
0.822 0.178 0.000
H92 Otalgia and effusion of ear
0.821 0.179 0.000
Q61 Cystic kidney disease
0.821 0.179 0.000
M54.4 Lumbago with sciatica
0.819 0.181 0.000
H91 Other hearing loss
0.817 0.183 0.000
G30 Alzheimer's disease
0.815 0.185 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.815 0.185 0.000
I05-I09 Chronic rheumatic heart diseases
0.813 0.187 0.000
H55-H59 Other disorders of eye and adnexa
0.811 0.189 0.000
S10-S19 Injuries to the neck
0.806 0.194 0.000
Chapter XX External causes of morbidity and mortality
0.806 0.194 0.000
L20-L30 Dermatitis and eczema
0.804 0.196 0.000
M25.8 Other specified joint disorders
0.798 0.202 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.798 0.202 0.000
S80-S89 Injuries to the knee and lower leg
0.793 0.207 0.000
F20 Schizophrenia
0.791 0.209 0.000
M84 Disorders of continuity of bone
0.790 0.210 0.000
M30 Polyarteritis nodosa and related conditions
0.790 0.210 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.789 0.211 0.000
I77 Other disorders of arteries and arterioles
0.786 0.214 0.000
M32 Systemic lupus erythematosus
0.785 0.215 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.784 0.216 0.000
D60-D64 Aplastic and other anaemias
0.784 0.216 0.000
I25.3 Aneurysm of heart
0.780 0.220 0.000
M24 Other specific joint derangements
0.780 0.220 0.000
M33 Dermatopolymyositis
0.779 0.221 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.779 0.221 0.000
I73.9 Peripheral vascular disease, unspecified
0.776 0.224 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.775 0.225 0.000
S62 Fracture at wrist and hand level
0.771 0.229 0.000
M60-M63 Disorders of muscles
0.770 0.230 0.000
L08 Other local infections of skin and subcutaneous tissue
0.769 0.231 0.000
S70-S79 Injuries to the hip and thigh
0.769 0.231 0.000
G30.9 Alzheimer's disease, unspecified
0.768 0.232 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.765 0.235 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.765 0.235 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.764 0.236 0.000
M90 Osteopathies in diseases classified elsewhere
0.763 0.237 0.000
H91.9 Hearing loss, unspecified
0.763 0.237 0.000
I45 Other conduction disorders
0.763 0.237 0.000
I51 Complications and ill-defined descriptions of heart disease
0.762 0.238 0.000
E14 Unspecified diabetes mellitus
0.759 0.241 0.000
H10-H13 Disorders of conjunctiva
0.756 0.244 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.755 0.245 0.000
H92.0 Otalgia
0.752 0.248 0.000
M48.06 Spinal stenosis (Lumbar region)
0.752 0.248 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.748 0.252 0.000
S99 Other and unspecified injuries of ankle and foot
0.747 0.252 0.000
M25.3 Other instability of joint
0.747 0.253 0.000
F29 Unspecified nonorganic psychosis
0.741 0.258 0.000
M48.09 Spinal stenosis (Site unspecified)
0.741 0.259 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.740 0.260 0.000
I10-I15 Hypertensive diseases
0.738 0.262 0.000
I25.5 Ischaemic cardiomyopathy
0.738 0.262 0.000
I49 Other cardiac arrhythmias
0.738 0.262 0.000
F80-F89 Disorders of psychological development
0.737 0.263 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.737 0.263 0.000
H30-H36 Disorders of choroid and retina
0.733 0.267 0.000
L65 Other nonscarring hair loss
0.733 0.267 0.000
S40-S49 Injuries to the shoulder and upper arm
0.733 0.267 0.000
S91 Open wound of ankle and foot
0.731 0.269 0.000
L05 Pilonidal cyst
0.731 0.269 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.731 0.269 0.000
M22 Disorders of patella
0.726 0.274 0.000
I22 Subsequent myocardial infarction
0.724 0.276 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.724 0.276 0.000
S20-S29 Injuries to the thorax
0.724 0.276 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.723 0.277 0.000
E70-E90 Metabolic disorders
0.722 0.278 0.000
G62 Other polyneuropathies
0.720 0.280 0.000
I21.4 Acute subendocardial myocardial infarction
0.720 0.280 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.719 0.281 0.000
I70 Atherosclerosis
0.719 0.281 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.719 0.281 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.719 0.281 0.000
I08 Multiple valve diseases
0.719 0.281 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.714 0.286 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.714 0.286 0.000
G90-G99 Other disorders of the nervous system
0.714 0.286 0.000
F20.9 Schizophrenia, unspecified
0.713 0.287 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.713 0.287 0.000
M53 Other dorsopathies, not elsewhere classified
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.712 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
S92.3 Fracture of metatarsal bone
0.712 0.288 0.000
M54.8 Other dorsalgia
0.711 0.289 0.000
M54.6 Pain in thoracic spine
0.711 0.289 0.000
M54.0 Panniculitis affecting regions of neck and back
0.711 0.289 0.000
Q80-Q89 Other congenital malformations
0.711 0.289 0.000
M54.2 Cervicalgia
0.711 0.289 0.000
M82 Osteoporosis in diseases classified elsewhere
0.711 0.289 0.000
E10.3 With ophthalmic complications
0.710 0.290 0.000
T33-T35 Frostbite
0.709 0.290 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.290 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.709 0.290 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.290 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.708 0.292 0.000
M35.8 Other specified systemic involvement of connective tissue
0.708 0.292 0.000
M35.7 Hypermobility syndrome
0.708 0.292 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.708 0.292 0.000
M35.5 Multifocal fibrosclerosis
0.708 0.292 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.708 0.292 0.000
M35.2 Behcet's disease
0.708 0.292 0.000
M35.1 Other overlap syndromes
0.708 0.292 0.000
Q61.2 Polycystic kidney, adult type
0.708 0.292 0.000
T66-T78 Other and unspecified effects of external causes
0.707 0.293 0.000
M81 Osteoporosis without pathological fracture
0.705 0.295 0.000
E10.9 Without complications
0.704 0.296 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.704 0.296 0.000
M54.1 Radiculopathy
0.704 0.296 0.000
F30-F39 Mood [affective] disorders
0.704 0.296 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.703 0.297 0.000
I47.0 Reentry ventricular arrhythmia
0.703 0.297 0.000
M54.55 Low back pain (Thoracolumbar region)
0.703 0.297 0.000
M54.54 Low back pain-Thoracic
0.703 0.297 0.000
M54.53 Low back pain-Cervicothoracic
0.703 0.297 0.000
M54.52 Low back pain-Cervical
0.703 0.297 0.000
M54.51 Low back pain-Occipit-atl-axl
0.703 0.297 0.000
M54.50 Low back pain (Multiple sites in spine)
0.703 0.297 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.699 0.301 0.000
M49 Spondylopathies in diseases classified elsewhere
0.698 0.302 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.698 0.302 0.000
M25.84 Other specified joint disorders (Hand)
0.697 0.302 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.697 0.303 0.000
L73 Other follicular disorders
0.696 0.304 0.000
L10-L14 Bullous disorders
0.696 0.304 0.000
L50-L54 Urticaria and erythema
0.695 0.305 0.000
M70-M79 Other soft tissue disorders
0.695 0.305 0.000
Q00-Q07 Congenital malformations of the nervous system
0.694 0.306 0.000
M25.5 Pain in joint
0.694 0.306 0.000
M85 Other disorders of bone density and structure
0.694 0.306 0.000
H90 Conductive and sensorineural hearing loss
0.690 0.310 0.000
M90.7 Fracture of bone in neoplastic disease
0.689 0.311 0.000
E14.9 Without complications
0.689 0.311 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.688 0.311 0.000
S50-S59 Injuries to the elbow and forearm
0.687 0.312 0.000
H57 Other disorders of eye and adnexa
0.687 0.313 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.687 0.313 0.000
Q63 Other congenital malformations of kidney
0.687 0.313 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.687 0.313 0.000
S93.1 Dislocation of toe(s)
0.687 0.313 0.000
S80 Superficial injury of lower leg
0.686 0.314 0.000
M50 Cervical disk disorders
0.685 0.315 0.000
L71 Rosacea
0.685 0.315 0.000
L75 Apocrine sweat disorders
0.685 0.315 0.000
L74 Eccrine sweat disorders
0.685 0.315 0.000
L70 Acne
0.685 0.315 0.000
L68 Hypertrichosis
0.685 0.315 0.000
L67 Hair colour and hair shaft abnormalities
0.685 0.315 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.685 0.315 0.000
L64 Androgenic alopecia
0.685 0.315 0.000
L63 Alopecia areata
0.685 0.315 0.000
L62 Nail disorders in diseases classified elsewhere
0.685 0.315 0.000
E28 Ovarian dysfunction
0.684 0.316 0.000
S98 Traumatic amputation of ankle and foot
0.684 0.316 0.000
S97 Crushing injury of ankle and foot
0.684 0.316 0.000
S95 Injury of blood vessels at ankle and foot level
0.684 0.316 0.000
S94 Injury of nerves at ankle and foot level
0.684 0.316 0.000
S90 Superficial injury of ankle and foot
0.684 0.316 0.000
Q50-Q56 Congenital malformations of genital organs
0.683 0.317 0.000
S92.0 Fracture of calcaneus
0.683 0.317 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.683 0.317 0.000
I35.0 Aortic (valve) stenosis
0.683 0.317 0.000
M54.57 Low back pain (Lumbosacral region)
0.682 0.318 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.680 0.320 0.000
M25.0 Haemarthrosis
0.680 0.320 0.000
M92 Other juvenile osteochondrosis
0.679 0.321 0.000
Q61.3 Polycystic kidney, unspecified
0.679 0.321 0.000
L72.2 Steatocystoma multiplex
0.678 0.322 0.000
Q61.0 Congenital single renal cyst
0.678 0.322 0.000
M34.1 CR(E)ST syndrome
0.677 0.323 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.676 0.324 0.000
Q35-Q37 Cleft lip and cleft palate
0.676 0.324 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.676 0.324 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.676 0.324 0.000
M54.3 Sciatica
0.675 0.325 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.675 0.325 0.000
L27 Dermatitis due to substances taken internally
0.674 0.326 0.000
I74 Arterial embolism and thrombosis
0.674 0.326 0.000
S62.6 Fracture of other finger
0.673 0.327 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.672 0.328 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.672 0.328 0.000
S92.4 Fracture of great toe
0.671 0.329 0.000
F25 Schizoaffective disorders
0.670 0.329 0.000
I72 Other aneurysm
0.670 0.330 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.670 0.330 0.000
S62.3 Fracture of other metacarpal bone
0.670 0.330 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.669 0.331 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.669 0.331 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.668 0.332 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.668 0.332 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.668 0.332 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.668 0.332 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.668 0.332 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.668 0.332 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.668 0.332 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.668 0.332 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
F22 Persistent delusional disorders
0.668 0.332 0.000
I33 Acute and subacute endocarditis
0.668 0.332 0.000
D64 Other anaemias
0.667 0.333 0.000
E40-E46 Malnutrition
0.665 0.335 0.000
E23 Hypofunction and other disorders of pituitary gland
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.663 0.337 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.662 0.337 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.662 0.338 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.662 0.338 0.000
M48.02 Spinal stenosis (Cervical region)
0.662 0.338 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.661 0.339 0.000
E27 Other disorders of adrenal gland
0.661 0.339 0.000
H46 Optic neuritis
0.661 0.339 0.000
I30 Acute pericarditis
0.658 0.342 0.000
H65-H75 Diseases of middle ear and mastoid
0.658 0.342 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.657 0.343 0.000
E24 Cushing's syndrome
0.657 0.343 0.000
M86 Osteomyelitis
0.656 0.344 0.000
E13 Other specified diabetes mellitus
0.656 0.344 0.000
F60-F69 Disorders of adult personality and behaviour
0.655 0.345 0.000
E20 Hypoparathyroidism
0.654 0.346 0.000
G30.0 Alzheimer's disease with early onset
0.653 0.347 0.000
E10.5 With peripheral circulatory complications
0.653 0.347 0.000
E50-E64 Other nutritional deficiencies
0.652 0.347 0.000
S12 Fracture of neck
0.652 0.348 0.000
E87.6 Hypokalaemia
0.652 0.348 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.651 0.349 0.000
H92.1 Otorrhoea
0.650 0.350 0.000
M94 Other disorders of cartilage
0.649 0.351 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.649 0.351 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.648 0.352 0.000
F70-F79 Mental retardation
0.648 0.352 0.000
I12 Hypertensive renal disease
0.648 0.352 0.000
M83 Adult osteomalacia
0.647 0.353 0.000
G36 Other acute disseminated demyelination
0.646 0.354 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.645 0.354 0.000
M25.9 Joint disorder, unspecified
0.645 0.355 0.000
M25.2 Flail joint
0.645 0.355 0.000
M25.1 Fistula of joint
0.645 0.355 0.000
G37 Other demyelinating diseases of central nervous system
0.645 0.355 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.644 0.356 0.000
E10.2 With renal complications
0.644 0.356 0.000
I73.0 Raynaud's syndrome
0.644 0.356 0.000
M35.0 Sicca syndrome [Sjogren]
0.643 0.357 0.000
T79-T79 Certain early complications of trauma
0.643 0.357 0.000
Chapter XXII Codes for special purposes
0.641 0.358 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.640 0.359 0.000
H11 Other disorders of conjunctiva
0.640 0.360 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.639 0.360 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.639 0.360 0.000
M40-M43 Deforming dorsopathies
0.639 0.361 0.000
I51.7 Cardiomegaly
0.639 0.361 0.000
M25.34 Other instability of joint (Hand)
0.638 0.362 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.637 0.363 0.000
G83 Other paralytic syndromes
0.637 0.363 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.636 0.364 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.636 0.364 0.000
M24.2 Disorder of ligament
0.636 0.364 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.636 0.364 0.000
M21 Other acquired deformities of limbs
0.635 0.365 0.000
G61 Inflammatory polyneuropathy
0.634 0.366 0.000
E10.4 With neurological complications
0.634 0.366 0.000
E34 Other endocrine disorders
0.634 0.366 0.000
F20.0 Paranoid schizophrenia
0.633 0.367 0.000
M48.9 Spondylopathy, unspecified
0.633 0.367 0.000
M48.8 Other specified spondylopathies
0.633 0.367 0.000
M48.4 Fatigue fracture of vertebra
0.633 0.367 0.000
M48.3 Traumatic spondylopathy
0.633 0.367 0.000
M48.2 Kissing spine
0.633 0.367 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.633 0.367 0.000
G62.9 Polyneuropathy, unspecified
0.633 0.367 0.000
W00-W19 Falls
0.633 0.367 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.632 0.368 0.000
L04 Acute lymphadenitis
0.631 0.369 0.000
L01 Impetigo
0.631 0.369 0.000
L00 Staphylococcal scalded skin syndrome
0.631 0.369 0.000
Q64 Other congenital malformations of urinary system
0.631 0.369 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.631 0.369 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.631 0.369 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.631 0.369 0.000
M87 Osteonecrosis
0.630 0.370 0.000
M34.9 Systemic sclerosis, unspecified
0.629 0.371 0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level
0.629 0.371 0.000
E12 Malnutrition-related diabetes mellitus
0.629 0.371 0.000
H53.6 Night blindness
0.629 0.371 0.000
H53.5 Colour vision deficiencies
0.629 0.371 0.000
H53.3 Other disorders of binocular vision
0.629 0.371 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.626 0.374 0.000
S64 Injury of nerves at wrist and hand level
0.626 0.374 0.000
M33.1 Other dermatomyositis
0.625 0.375 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.624 0.376 0.000
S67 Crushing injury of wrist and hand
0.624 0.376 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.624 0.376 0.000
M51 Other intervertebral disk disorders
0.623 0.377 0.000
F23 Acute and transient psychotic disorders
0.622 0.377 0.000
F28 Other nonorganic psychotic disorders
0.622 0.377 0.000
F24 Induced delusional disorder
0.622 0.377 0.000
F21 Schizotypal disorder
0.622 0.377 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.622 0.378 0.000
M25.86 Other specified joint disorders (Lower leg)
0.622 0.378 0.000
I44 Atrioventricular and left bundle-branch block
0.622 0.378 0.000
D62 Acute posthaemorrhagic anaemia
0.621 0.379 0.000
H93 Other disorders of ear, not elsewhere classified
0.621 0.379 0.000
F33 Recurrent depressive disorder
0.621 0.379 0.000
L28 Lichen simplex chronicus and prurigo
0.621 0.379 0.000
T42.4 Benzodiazepines
0.620 0.380 0.000
L05.9 Pilonidal cyst without abscess
0.620 0.380 0.000
H49 Paralytic strabismus
0.620 0.380 0.000
D68 Other coagulation defects
0.618 0.382 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.618 0.382 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.618 0.382 0.000
F81 Specific developmental disorders of scholastic skills
0.618 0.382 0.000
D63.0 Anaemia in neoplastic disease
0.617 0.383 0.000
M89 Other disorders of bone
0.616 0.384 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.614 0.386 0.000
M31 Other necrotising vasculopathies
0.613 0.387 0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.613 0.387 0.000
I77.6 Arteritis, unspecified
0.613 0.387 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.612 0.388 0.000
S92.30 Fracture of metatarsal bone (closed)
0.612 0.388 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.611 0.389 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.611 0.389 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.611 0.389 0.000
M48.04 Spinal stenosis (Thoracic region)
0.611 0.389 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.611 0.389 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.611 0.389 0.000
S92.9 Fracture of foot, unspecified
0.611 0.389 0.000
S92.7 Multiple fractures of foot
0.611 0.389 0.000
S92.5 Fracture of other toe
0.611 0.389 0.000
S92.2 Fracture of other tarsal bone(s)
0.611 0.389 0.000
S92.1 Fracture of talus
0.611 0.389 0.000
H16 Keratitis
0.610 0.389 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.610 0.390 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.609 0.391 0.000
H55 Nystagmus and other irregular eye movements
0.608 0.392 0.000
S72 Fracture of femur
0.608 0.392 0.000
W50-W64 Exposure to animate mechanical forces
0.608 0.392 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.608 0.392 0.000
F99-F99 Unspecified mental disorder
0.607 0.392 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.607 0.393 0.000
G60 Hereditary and idiopathic neuropathy
0.605 0.394 0.000
G64 Other disorders of peripheral nervous system
0.605 0.394 0.000
I77.1 Stricture of artery
0.605 0.395 0.000
I73.8 Other specified peripheral vascular diseases
0.605 0.395 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.605 0.395 0.000
M62 Other disorders of muscle
0.605 0.395 0.000
H53.4 Visual field defects
0.605 0.395 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.605 0.395 0.000
E32 Diseases of thymus
0.605 0.395 0.000
E31 Polyglandular dysfunction
0.605 0.395 0.000
E30 Disorders of puberty, not elsewhere classified
0.605 0.395 0.000
E26 Hyperaldosteronism
0.605 0.395 0.000
E25 Adrenogenital disorders
0.605 0.395 0.000
H54 Blindness and low vision
0.604 0.396 0.000
H20 Iridocyclitis
0.604 0.396 0.000
W20-W49 Exposure to inanimate mechanical forces
0.603 0.397 0.000
M65-M68 Disorders of synovium and tendon
0.602 0.398 0.000
E22 Hyperfunction of pituitary gland
0.601 0.398 0.000
V40-V49 Car occupant injured in transport accident
0.601 0.399 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.601 0.399 0.000
S99.9 Unspecified injury of ankle and foot
0.600 0.400 0.000
I50.9 Heart failure, unspecified
0.599 0.401 0.000
I05 Rheumatic mitral valve diseases
0.599 0.401 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.599 0.401 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.598 0.402 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.598 0.402 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.598 0.402 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.598 0.402 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.598 0.402 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.598 0.402 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.598 0.402 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.598 0.402 0.000
T36 Poisoning by systemic antibiotics
0.598 0.402 0.000
D55-D59 Haemolytic anaemias
0.598 0.402 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.598 0.402 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.597 0.403 0.000
M88 Paget's disease of bone [osteitis deformans]
0.597 0.403 0.000
M93 Other osteochondropathies
0.597 0.403 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.597 0.403 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.597 0.403 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.597 0.403 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.597 0.403 0.000
I45.1 Other and unspecified right bundle-branch block
0.597 0.403 0.000
M45 Ankylosing spondylitis
0.596 0.404 0.000
G90 Disorders of autonomic nervous system
0.596 0.404 0.000
X60-X84 Intentional self-harm
0.595 0.404 0.000
L40-L45 Papulosquamous disorders
0.595 0.405 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.595 0.405 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.595 0.405 0.000
S65 Injury of blood vessels at wrist and hand level
0.595 0.405 0.000
E10.8 With unspecified complications
0.594 0.405 0.000
E10.7 With multiple complications
0.594 0.405 0.000
E10.6 With other specified complications
0.594 0.405 0.000
E10.0 With coma
0.594 0.405 0.000
Q76 Congenital malformations of spine and bony thorax
0.594 0.406 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.594 0.406 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.593 0.407 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.593 0.407 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.593 0.407 0.000
T13 Other injuries of lower limb, level unspecified
0.593 0.407 0.000
T82.1 Mechanical complication of cardiac electronic device
0.592 0.408 0.000
I51.9 Heart disease, unspecified
0.592 0.408 0.000
G82 Paraplegia and tetraplegia
0.592 0.408 0.000
I34 Nonrheumatic mitral valve disorders
0.592 0.408 0.000
M34.8 Other forms of systemic sclerosis
0.591 0.409 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.591 0.409 0.000
M34.0 Progressive systemic sclerosis
0.591 0.409 0.000
H53.1 Subjective visual disturbances
0.589 0.411 0.000
I24.1 Dressler's syndrome
0.589 0.411 0.000
H92.2 Otorrhagia
0.589 0.411 0.000
Q61.9 Cystic kidney disease, unspecified
0.588 0.412 0.000
Q61.8 Other cystic kidney diseases
0.588 0.412 0.000
Q61.5 Medullary cystic kidney
0.588 0.412 0.000
Q61.4 Renal dysplasia
0.588 0.412 0.000
Q61.1 Polycystic kidney, infantile type
0.588 0.412 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.588 0.412 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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