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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79917365
log Bayes Factor = 15.1303
Chromosome 8   position 67,459,400  (GRCh37) Explore rs79917365 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
K70-K77 Diseases of liver
0.997 0.003 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.992 0.008 0.000
M45-M49 Spondylopathies
0.991 0.009 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.988 0.012 0.000
Chapter IX Diseases of the circulatory system
0.987 0.013 0.000
G56 Mononeuropathies of upper limb
0.979 0.021 0.000
M20 Acquired deformities of fingers and toes
0.978 0.022 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.978 0.022 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.975 0.025 0.000
K70 Alcoholic liver disease
0.968 0.032 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.963 0.037 0.000
M54 Dorsalgia
0.962 0.038 0.000
I10-I15 Hypertensive diseases
0.961 0.039 0.000
K29 Gastritis and duodenitis
0.960 0.040 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.960 0.040 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.958 0.042 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.958 0.042 0.000
G56.0 Carpal tunnel syndrome
0.958 0.042 0.000
Chapter VIII Diseases of the ear and mastoid process
0.952 0.048 0.000
M47 Spondylosis
0.948 0.052 0.000
M15-M19 Arthrosis
0.945 0.055 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.942 0.058 0.000
M23 Internal derangement of knee
0.940 0.060 0.000
E10-E14 Diabetes mellitus
0.940 0.060 0.000
F17.1 Harmful use
0.937 0.063 0.000
M20.2 Hallux rigidus
0.937 0.063 0.000
K22 Other diseases of oesophagus
0.936 0.064 0.000
I10 Essential (primary) hypertension
0.930 0.070 0.000
I60-I69 Cerebrovascular diseases
0.929 0.071 0.000
F10.0 Acute intoxication
0.928 0.072 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.925 0.075 0.000
M48 Other spondylopathies
0.925 0.075 0.000
K22.1 Ulcer of oesophagus
0.922 0.078 0.000
E11 Non-insulin-dependent diabetes mellitus
0.918 0.082 0.000
M50 Cervical disk disorders
0.917 0.083 0.000
M20.5 Other deformities of toe(s) (acquired)
0.912 0.088 0.000
E11.9 Without complications
0.906 0.094 0.000
Chapter XIV Diseases of the genitourinary system
0.904 0.096 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.904 0.096 0.000
H65-H75 Diseases of middle ear and mastoid
0.902 0.098 0.000
M51 Other intervertebral disk disorders
0.902 0.098 0.000
G40-G47 Episodic and paroxysmal disorders
0.900 0.100 0.000
G50 Disorders of trigeminal nerve
0.899 0.101 0.000
K29.6 Other gastritis
0.898 0.102 0.000
M47.8 Other spondylosis
0.897 0.103 0.000
K04 Diseases of pulp and periapical tissues
0.895 0.105 0.000
K70.9 Alcoholic liver disease, unspecified
0.893 0.107 0.000
K76 Other diseases of liver
0.885 0.115 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.881 0.119 0.000
K74 Fibrosis and cirrhosis of liver
0.881 0.119 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.880 0.120 0.000
M48.0 Spinal stenosis
0.878 0.122 0.000
K14 Diseases of tongue
0.870 0.130 0.000
N20-N23 Urolithiasis
0.870 0.130 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.867 0.133 0.000
M25 Other joint disorders, not elsewhere classified
0.863 0.137 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.861 0.139 0.000
M19 Other arthrosis
0.860 0.140 0.000
N20 Calculus of kidney and ureter
0.860 0.140 0.000
K70.3 Alcoholic cirrhosis of liver
0.859 0.140 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.856 0.144 0.000
K31 Other diseases of stomach and duodenum
0.856 0.144 0.000
E20-E35 Disorders of other endocrine glands
0.855 0.145 0.000
M20.3 Other deformity of hallux (acquired)
0.848 0.152 0.000
N17-N19 Renal failure
0.847 0.153 0.000
M47.82 Other spondylosis (Cervical region)
0.846 0.154 0.000
I65.2 Occlusion and stenosis of carotid artery
0.846 0.154 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.842 0.158 0.000
S20-S29 Injuries to the thorax
0.841 0.159 0.000
G56.2 Lesion of ulnar nerve
0.840 0.160 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.836 0.164 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.834 0.166 0.000
F10.2 Dependence syndrome
0.834 0.166 0.000
M54.2 Cervicalgia
0.833 0.167 0.000
H72 Perforation of tympanic membrane
0.833 0.167 0.000
G50.0 Trigeminal neuralgia
0.831 0.169 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.828 0.172 0.000
M54.3 Sciatica
0.827 0.173 0.000
M48.06 Spinal stenosis (Lumbar region)
0.827 0.173 0.000
K29.8 Duodenitis
0.820 0.180 0.000
S70-S79 Injuries to the hip and thigh
0.820 0.180 0.000
M19.9 Arthrosis, unspecified
0.819 0.181 0.000
K12 Stomatitis and related lesions
0.814 0.186 0.000
K73 Chronic hepatitis, not elsewhere classified
0.814 0.186 0.000
M91-M94 Chondropathies
0.812 0.188 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.812 0.188 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.809 0.191 0.000
M51.2 Other specified intervertebral disk displacement
0.809 0.191 0.000
N20.0 Calculus of kidney
0.808 0.192 0.000
K65-K67 Diseases of peritoneum
0.807 0.193 0.000
I05-I09 Chronic rheumatic heart diseases
0.807 0.193 0.000
K76.6 Portal hypertension
0.806 0.194 0.000
Chapter VII Diseases of the eye and adnexa
0.806 0.194 0.000
K31.8 Other specified diseases of stomach and duodenum
0.804 0.196 0.000
T66-T78 Other and unspecified effects of external causes
0.802 0.198 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.801 0.199 0.000
K14.8 Other diseases of tongue
0.801 0.199 0.000
N20.1 Calculus of ureter
0.800 0.200 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.800 0.200 0.000
G30-G32 Other degenerative diseases of the nervous system
0.799 0.201 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.799 0.201 0.000
M54.5 Low back pain
0.799 0.201 0.000
M17 Gonarthrosis [arthrosis of knee]
0.798 0.202 0.000
K04.8 Radicular cyst
0.797 0.203 0.000
K29.1 Other acute gastritis
0.796 0.204 0.000
K75 Other inflammatory liver diseases
0.795 0.205 0.000
H60-H62 Diseases of external ear
0.794 0.206 0.000
I85 Oesophageal varices
0.793 0.207 0.000
M18 Arthrosis of first carpometacarpal joint
0.792 0.208 0.000
I11 Hypertensive heart disease
0.790 0.210 0.000
Chapter XXI Factors influencing health status and contact with health services
0.789 0.211 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.787 0.213 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.785 0.215 0.000
G20-G26 Extrapyramidal and movement disorders
0.784 0.216 0.000
S80-S89 Injuries to the knee and lower leg
0.784 0.216 0.000
N18 Chronic renal failure
0.784 0.216 0.000
M23.3 Other meniscus derangements
0.784 0.216 0.000
K72 Hepatic failure, not elsewhere classified
0.783 0.217 0.000
G44 Other headache syndromes
0.782 0.218 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.781 0.219 0.000
G90-G99 Other disorders of the nervous system
0.780 0.220 0.000
K29.0 Acute haemorrhagic gastritis
0.779 0.221 0.000
E14 Unspecified diabetes mellitus
0.779 0.221 0.000
Z03.4 Observation for suspected myocardial infarction
0.778 0.222 0.000
E28 Ovarian dysfunction
0.775 0.225 0.000
K55-K64 Other diseases of intestines
0.775 0.225 0.000
T43.2 Other and unspecified antidepressants
0.774 0.226 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.771 0.229 0.000
M45 Ankylosing spondylitis
0.771 0.229 0.000
M50.3 Other cervical disk degeneration
0.771 0.229 0.000
F17.2 Dependence syndrome
0.769 0.231 0.000
K74.3 Primary biliary cirrhosis
0.769 0.231 0.000
K70.4 Alcoholic hepatic failure
0.769 0.231 0.000
I63 Cerebral infarction
0.767 0.233 0.000
F80-F89 Disorders of psychological development
0.766 0.234 0.000
K04.7 Periapical abscess without sinus
0.765 0.235 0.000
M23.8 Other internal derangements of knee
0.764 0.236 0.000
T81 Complications of procedures, not elsewhere classified
0.763 0.237 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.762 0.238 0.000
Chapter XXII Codes for special purposes
0.761 0.239 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.760 0.240 0.000
M46 Other inflammatory spondylopathies
0.760 0.240 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.759 0.241 0.000
G51 Facial nerve disorders
0.757 0.243 0.000
M54.1 Radiculopathy
0.757 0.243 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.755 0.245 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.755 0.245 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.754 0.246 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.751 0.249 0.000
G47 Sleep disorders
0.749 0.251 0.000
M47.2 Other spondylosis with radiculopathy
0.747 0.252 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.747 0.253 0.000
M50.0 Cervical disk disorder with myelopathy
0.746 0.254 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.746 0.254 0.000
K25 Gastric ulcer
0.744 0.256 0.000
T79-T79 Certain early complications of trauma
0.744 0.256 0.000
M65-M68 Disorders of synovium and tendon
0.742 0.258 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.742 0.258 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.742 0.258 0.000
M24 Other specific joint derangements
0.742 0.258 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.742 0.258 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.741 0.259 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.741 0.259 0.000
M86-M90 Other osteopathies
0.741 0.259 0.000
M54.22 Cervicalgia (Cervical region)
0.741 0.259 0.000
G57 Mononeuropathies of lower limb
0.740 0.260 0.000
T58 Toxic effect of carbon monoxide
0.739 0.261 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.737 0.263 0.000
S90-S99 Injuries to the ankle and foot
0.736 0.263 0.000
K83 Other diseases of biliary tract
0.736 0.264 0.000
M51.8 Other specified intervertebral disk disorders
0.735 0.265 0.000
K29.3 Chronic superficial gastritis
0.732 0.268 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.732 0.268 0.000
M54.9 Dorsalgia, unspecified
0.731 0.269 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.730 0.270 0.000
M35 Other systemic involvement of connective tissue
0.730 0.270 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.730 0.270 0.000
Chapter X Diseases of the respiratory system
0.728 0.272 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.728 0.272 0.000
M47.9 Spondylosis, unspecified
0.725 0.275 0.000
I86 Varicose veins of other sites
0.725 0.275 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.725 0.275 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.724 0.276 0.000
G70-G73 Diseases of myoneural junction and muscle
0.723 0.277 0.000
E40-E46 Malnutrition
0.722 0.278 0.000
M50.1 Cervical disk disorder with radiculopathy
0.722 0.278 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.719 0.281 0.000
G43 Migraine
0.719 0.281 0.000
H71 Cholesteatoma of middle ear
0.718 0.282 0.000
E28.2 Polycystic ovarian syndrome
0.718 0.282 0.000
M05-M14 Inflammatory polyarthropathies
0.718 0.282 0.000
K07 Dentofacial anomalies [including malocclusion]
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M40-M43 Deforming dorsopathies
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.715 0.285 0.000
K71 Toxic liver disease
0.715 0.285 0.000
M50.2 Other cervical disk displacement
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
M21 Other acquired deformities of limbs
0.715 0.285 0.000
M17.9 Gonarthrosis, unspecified
0.714 0.286 0.000
M53 Other dorsopathies, not elsewhere classified
0.714 0.286 0.000
G58 Other mononeuropathies
0.713 0.287 0.000
G54 Nerve root and plexus disorders
0.713 0.287 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.713 0.287 0.000
G52 Disorders of other cranial nerves
0.713 0.287 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.713 0.287 0.000
H74 Other disorders of middle ear and mastoid
0.712 0.287 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.712 0.288 0.000
H72.0 Central perforation of tympanic membrane
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
H90-H95 Other disorders of ear
0.712 0.288 0.000
N20.2 Calculus of kidney with calculus of ureter
0.711 0.289 0.000
F99-F99 Unspecified mental disorder
0.711 0.289 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.711 0.289 0.000
F70-F79 Mental retardation
0.711 0.289 0.000
F60-F69 Disorders of adult personality and behaviour
0.711 0.289 0.000
T39.1 4-Aminophenol derivatives
0.711 0.289 0.000
K58 Irritable bowel syndrome
0.711 0.289 0.000
M49 Spondylopathies in diseases classified elsewhere
0.710 0.290 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.710 0.290 0.000
I12 Hypertensive renal disease
0.709 0.291 0.000
M54.39 Sciatica (Site unspecified)
0.709 0.291 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.708 0.291 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.708 0.291 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.708 0.291 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.708 0.291 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.708 0.291 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.708 0.291 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.708 0.291 0.000
F11 Mental and behavioural disorders due to use of opioids
0.708 0.291 0.000
Z03.3 Observation for suspected nervous system disorder
0.708 0.292 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.708 0.292 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
I60 Subarachnoid haemorrhage
0.708 0.292 0.000
M25.5 Pain in joint
0.706 0.294 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.706 0.294 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.704 0.296 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.702 0.298 0.000
G56.8 Other mononeuropathies of upper limb
0.702 0.298 0.000
G56.4 Causalgia
0.702 0.298 0.000
G56.3 Lesion of radial nerve
0.702 0.298 0.000
G56.1 Other lesions of median nerve
0.702 0.298 0.000
I82 Other venous embolism and thrombosis
0.701 0.298 0.000
M20.0 Deformity of finger(s)
0.701 0.299 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.701 0.299 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.701 0.299 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.701 0.299 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.701 0.299 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.701 0.299 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.701 0.299 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.701 0.299 0.000
T36 Poisoning by systemic antibiotics
0.701 0.299 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.700 0.300 0.000
K65 Peritonitis
0.700 0.300 0.000
K55 Vascular disorders of intestine
0.700 0.300 0.000
I85.9 Oesophageal varices without bleeding
0.700 0.300 0.000
K28 Gastrojejunal ulcer
0.699 0.301 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.699 0.301 0.000
K29.4 Chronic atrophic gastritis
0.699 0.301 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.699 0.301 0.000
N00-N08 Glomerular diseases
0.697 0.303 0.000
I81 Portal vein thrombosis
0.697 0.303 0.000
K31.4 Gastric diverticulum
0.696 0.304 0.000
N19 Unspecified renal failure
0.695 0.305 0.000
Q60-Q64 Congenital malformations of the urinary system
0.695 0.305 0.000
K74.6 Other and unspecified cirrhosis of liver
0.694 0.306 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.694 0.306 0.000
K70.1 Alcoholic hepatitis
0.694 0.306 0.000
K70.0 Alcoholic fatty liver
0.694 0.306 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.693 0.307 0.000
M48.02 Spinal stenosis (Cervical region)
0.692 0.308 0.000
M25.8 Other specified joint disorders
0.692 0.308 0.000
K29.5 Chronic gastritis, unspecified
0.691 0.309 0.000
K76.9 Liver disease, unspecified
0.691 0.309 0.000
F17.9 Unspecified mental and behavioural disorder
0.690 0.310 0.000
F17.8 Other mental and behavioural disorders
0.690 0.310 0.000
F17.7 Residual and late-onset psychotic disorder
0.690 0.310 0.000
F17.6 Amnesic syndrome
0.690 0.310 0.000
F17.5 Psychotic disorder
0.690 0.310 0.000
F17.4 Withdrawal state with delirium
0.690 0.310 0.000
F17.3 Withdrawal state
0.690 0.310 0.000
F17.0 Acute intoxication
0.690 0.310 0.000
E11.2 With renal complications
0.690 0.310 0.000
M54.8 Other dorsalgia
0.689 0.310 0.000
M54.6 Pain in thoracic spine
0.689 0.310 0.000
M54.4 Lumbago with sciatica
0.689 0.310 0.000
M54.0 Panniculitis affecting regions of neck and back
0.689 0.310 0.000
E22 Hyperfunction of pituitary gland
0.689 0.310 0.000
I15 Secondary hypertension
0.689 0.311 0.000
I13 Hypertensive heart and renal disease
0.689 0.311 0.000
K29.9 Gastroduodenitis, unspecified
0.688 0.311 0.000
K29.2 Alcoholic gastritis
0.688 0.311 0.000
E50-E64 Other nutritional deficiencies
0.688 0.312 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.687 0.312 0.000
K10 Other diseases of jaws
0.687 0.313 0.000
K09 Cysts of oral region, not elsewhere classified
0.687 0.313 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.687 0.313 0.000
K03 Other diseases of hard tissues of teeth
0.687 0.313 0.000
K00 Disorders of tooth development and eruption
0.687 0.313 0.000
F10.9 Unspecified mental and behavioural disorder
0.687 0.313 0.000
F10.8 Other mental and behavioural disorders
0.687 0.313 0.000
F10.7 Residual and late-onset psychotic disorder
0.687 0.313 0.000
F10.6 Amnesic syndrome
0.687 0.313 0.000
F10.5 Psychotic disorder
0.687 0.313 0.000
F10.4 Withdrawal state with delirium
0.687 0.313 0.000
M31 Other necrotising vasculopathies
0.684 0.315 0.000
Z03.1 Observation for suspected malignant neoplasm
0.684 0.316 0.000
T51 Toxic effect of alcohol
0.684 0.316 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.683 0.317 0.000
S40-S49 Injuries to the shoulder and upper arm
0.683 0.317 0.000
K29.7 Gastritis, unspecified
0.682 0.318 0.000
K08 Other disorders of teeth and supporting structures
0.682 0.318 0.000
K11 Diseases of salivary glands
0.682 0.318 0.000
K73.9 Chronic hepatitis, unspecified
0.682 0.318 0.000
M80-M85 Disorders of bone density and structure
0.680 0.320 0.000
M47.1 Other spondylosis with myelopathy
0.679 0.321 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.679 0.321 0.000
M94 Other disorders of cartilage
0.678 0.322 0.000
M15 Polyarthrosis
0.677 0.322 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.677 0.323 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.676 0.324 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.675 0.325 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.675 0.325 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.675 0.325 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.675 0.325 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.675 0.325 0.000
K22.8 Other specified diseases of oesophagus
0.675 0.325 0.000
M23.9 Internal derangement of knee, unspecified
0.674 0.326 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.674 0.326 0.000
M23.5 Chronic instability of knee
0.674 0.326 0.000
M23.4 Loose body in knee
0.674 0.326 0.000
M23.1 Discoid meniscus (congenital)
0.674 0.326 0.000
M23.0 Cystic meniscus
0.674 0.326 0.000
E13 Other specified diabetes mellitus
0.674 0.326 0.000
E12 Malnutrition-related diabetes mellitus
0.674 0.326 0.000
I85.0 Oesophageal varices with bleeding
0.673 0.326 0.000
M25.56 Pain in joint (Lower leg)
0.673 0.327 0.000
G47.3 Sleep apnoea
0.672 0.328 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.672 0.328 0.000
F10.3 Withdrawal state
0.671 0.329 0.000
K22.5 Diverticulum of oesophagus, acquired
0.671 0.329 0.000
K22.3 Perforation of oesophagus
0.671 0.329 0.000
K22.0 Achalasia of cardia
0.671 0.329 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.671 0.329 0.000
N70 Salpingitis and oophoritis
0.671 0.329 0.000
H65 Nonsuppurative otitis media
0.670 0.329 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.669 0.331 0.000
M19.94 Arthrosis, unspecified (Hand)
0.668 0.332 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.668 0.332 0.000
K04.5 Chronic apical periodontitis
0.667 0.333 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.667 0.333 0.000
E65-E68 Obesity and other hyperalimentation
0.667 0.333 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.666 0.334 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.666 0.334 0.000
I62 Other nontraumatic intracranial haemorrhage
0.666 0.334 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.666 0.334 0.000
I61 Intracerebral haemorrhage
0.665 0.334 0.000
M48.09 Spinal stenosis (Site unspecified)
0.663 0.337 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.663 0.337 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.663 0.337 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.663 0.337 0.000
T85.2 Mechanical complication of intraocular lens
0.663 0.337 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.663 0.337 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.663 0.337 0.000
S60-S69 Injuries to the wrist and hand
0.663 0.337 0.000
M48.9 Spondylopathy, unspecified
0.663 0.337 0.000
M48.8 Other specified spondylopathies
0.663 0.337 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.663 0.337 0.000
M48.4 Fatigue fracture of vertebra
0.663 0.337 0.000
M48.3 Traumatic spondylopathy
0.663 0.337 0.000
M48.2 Kissing spine
0.663 0.337 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.663 0.337 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.663 0.337 0.000
K22.7 Barrett's oesophagus
0.662 0.338 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.662 0.338 0.000
N73 Other female pelvic inflammatory diseases
0.662 0.338 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.661 0.339 0.000
T78 Adverse effects, not elsewhere classified
0.660 0.340 0.000
K12.1 Other forms of stomatitis
0.660 0.340 0.000
Z13 Special screening examination for other diseases and disorders
0.660 0.340 0.000
E11.3 With ophthalmic complications
0.660 0.340 0.000
K12.3 Oral mucositis (ulcerative)
0.659 0.341 0.000
S27 Injury of other and unspecified intrathoracic organs
0.659 0.341 0.000
E11.8 With unspecified complications
0.658 0.341 0.000
E11.7 With multiple complications
0.658 0.341 0.000
E11.6 With other specified complications
0.658 0.341 0.000
E11.1 With ketoacidosis
0.658 0.341 0.000
E11.0 With coma
0.658 0.341 0.000
M50.9 Cervical disk disorder, unspecified
0.657 0.343 0.000
M50.8 Other cervical disk disorders
0.657 0.343 0.000
G44.2 Tension-type headache
0.656 0.344 0.000
H73 Other disorders of tympanic membrane
0.656 0.344 0.000
N10-N16 Renal tubulo-interstitial diseases
0.656 0.344 0.000
M25.4 Effusion of joint
0.655 0.344 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.655 0.345 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.655 0.345 0.000
N18.5 Chronic kidney disease, stage 5
0.655 0.345 0.000
J09-J18 Influenza and pneumonia
0.654 0.346 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.653 0.347 0.000
N18.0 End-stage renal disease
0.653 0.347 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.651 0.349 0.000
S72 Fracture of femur
0.651 0.349 0.000
K22.9 Disease of oesophagus, unspecified
0.651 0.349 0.000
H10-H13 Disorders of conjunctiva
0.651 0.349 0.000
I67 Other cerebrovascular diseases
0.650 0.349 0.000
M54.50 Low back pain (Multiple sites in spine)
0.650 0.350 0.000
E14.9 Without complications
0.649 0.351 0.000
N99-N99 Other disorders of the genitourinary system
0.649 0.351 0.000
T43.9 Psychotropic drug, unspecified
0.648 0.352 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.648 0.352 0.000
T43.6 Psychostimulants with abuse potential
0.648 0.352 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.648 0.352 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.648 0.352 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.648 0.352 0.000
K27 Peptic ulcer, site unspecified
0.648 0.352 0.000
T39.0 Salicylates
0.647 0.352 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.646 0.353 0.000
H70 Mastoiditis and related conditions
0.646 0.353 0.000
H69 Other disorders of Eustachian tube
0.646 0.353 0.000
H68 Eustachian salpingitis and obstruction
0.646 0.353 0.000
H67 Otitis media in diseases classified elsewhere
0.646 0.353 0.000
M51.3 Other specified intervertebral disk degeneration
0.646 0.354 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.646 0.354 0.000
M51.9 Intervertebral disk disorder, unspecified
0.646 0.354 0.000
M51.4 Schmorl's nodes
0.646 0.354 0.000
E27 Other disorders of adrenal gland
0.646 0.354 0.000
M17.0 Primary gonarthrosis, bilateral
0.645 0.354 0.000
K05 Gingivitis and periodontal diseases
0.645 0.355 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.645 0.355 0.000
G41 Status epilepticus
0.645 0.355 0.000
K14.0 Glossitis
0.645 0.355 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.645 0.355 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.645 0.355 0.000
G50.8 Other disorders of trigeminal nerve
0.645 0.355 0.000
G50.1 Atypical facial pain
0.645 0.355 0.000
M47.89 Other spondylosis (Site unspecified)
0.643 0.357 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.643 0.357 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.643 0.357 0.000
M47.84 Other spondylosis (Thoracic region)
0.643 0.357 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.643 0.357 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.643 0.357 0.000
H61 Other disorders of external ear
0.643 0.357 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.643 0.357 0.000
I07 Rheumatic tricuspid valve diseases
0.643 0.357 0.000
S79 Other and unspecified injuries of hip and thigh
0.643 0.357 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.642 0.358 0.000
K04.6 Periapical abscess with sinus
0.642 0.358 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.642 0.358 0.000
K04.3 Abnormal hard tissue formation in pulp
0.642 0.358 0.000
K04.2 Pulp degeneration
0.642 0.358 0.000
K04.1 Necrosis of pulp
0.642 0.358 0.000
K04.0 Pulpitis
0.642 0.358 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.641 0.359 0.000
Chapter XX External causes of morbidity and mortality
0.641 0.359 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.641 0.359 0.000
M22 Disorders of patella
0.640 0.360 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.640 0.360 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.639 0.361 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.639 0.361 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.639 0.361 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.637 0.363 0.000
K35-K38 Diseases of appendix
0.637 0.363 0.000
E10 Insulin-dependent diabetes mellitus
0.636 0.363 0.000
M54.36 Sciatica (Lumbar region)
0.636 0.364 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.636 0.364 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.635 0.365 0.000
K76.7 Hepatorenal syndrome
0.634 0.365 0.000
K76.5 Hepatic veno-occlusive disease
0.634 0.365 0.000
K76.4 Peliosis hepatis
0.634 0.365 0.000
K76.3 Infarction of liver
0.634 0.365 0.000
K76.2 Central haemorrhagic necrosis of liver
0.634 0.365 0.000
K76.1 Chronic passive congestion of liver
0.634 0.365 0.000
K83.8 Other specified diseases of biliary tract
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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