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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73204665
log Bayes Factor = 14.5549
Chromosome 8   position 9,621,236  (GRCh37) Explore rs73204665 on Ensembl!
Variant rs73204665 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.995 0.005 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.993 0.007 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.992 0.008 0.000
I83 Varicose veins of lower extremities
0.990 0.010 0.000
Chapter I Certain infectious and parasitic diseases
0.989 0.011 0.000
M25 Other joint disorders, not elsewhere classified
0.987 0.013 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.985 0.015 0.000
M54 Dorsalgia
0.979 0.021 0.000
Chapter VII Diseases of the eye and adnexa
0.970 0.030 0.000
M05-M14 Inflammatory polyarthropathies
0.969 0.031 0.000
I30-I52 Other forms of heart disease
0.964 0.036 0.000
M70-M79 Other soft tissue disorders
0.964 0.036 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.960 0.040 0.000
M54.5 Low back pain
0.960 0.040 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.959 0.041 0.000
I60-I69 Cerebrovascular diseases
0.955 0.045 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.954 0.046 0.000
M06 Other rheumatoid arthritis
0.953 0.047 0.000
M54.59 Low back pain (Site unspecified)
0.949 0.051 0.000
M25.5 Pain in joint
0.949 0.051 0.000
H53-H54 Visual disturbances and blindness
0.949 0.051 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.948 0.052 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.943 0.057 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.941 0.059 0.000
S00-S09 Injuries to the head
0.941 0.059 0.000
M06.9 Rheumatoid arthritis, unspecified
0.938 0.062 0.000
Chapter X Diseases of the respiratory system
0.928 0.072 0.000
F17.1 Harmful use
0.926 0.074 0.000
I50 Heart failure
0.925 0.075 0.000
J30-J39 Other diseases of upper respiratory tract
0.923 0.077 0.000
A30-A49 Other bacterial diseases
0.923 0.077 0.000
H53 Visual disturbances
0.916 0.084 0.000
Chapter VIII Diseases of the ear and mastoid process
0.916 0.084 0.000
M51 Other intervertebral disk disorders
0.915 0.085 0.000
M54.9 Dorsalgia, unspecified
0.907 0.093 0.000
I20-I25 Ischaemic heart diseases
0.899 0.101 0.000
S60-S69 Injuries to the wrist and hand
0.895 0.105 0.000
M25.56 Pain in joint (Lower leg)
0.895 0.105 0.000
M25.4 Effusion of joint
0.893 0.107 0.000
S00 Superficial injury of head
0.889 0.111 0.000
M31 Other necrotising vasculopathies
0.884 0.116 0.000
B15-B19 Viral hepatitis
0.884 0.116 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.883 0.117 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.883 0.117 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.879 0.121 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.877 0.123 0.000
H43-H45 Disorders of vitreous body and globe
0.875 0.125 0.000
I71 Aortic aneurysm and dissection
0.867 0.133 0.000
I81 Portal vein thrombosis
0.867 0.133 0.000
M79.6 Pain in limb
0.862 0.138 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.861 0.139 0.000
I67 Other cerebrovascular diseases
0.859 0.141 0.000
I50.0 Congestive heart failure
0.856 0.144 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.855 0.145 0.000
J32 Chronic sinusitis
0.851 0.149 0.000
S00.9 Superficial injury of head, part unspecified
0.847 0.153 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.847 0.153 0.000
F10.1 Harmful use
0.846 0.154 0.000
I45 Other conduction disorders
0.844 0.156 0.000
F30-F39 Mood [affective] disorders
0.844 0.156 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.841 0.159 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.839 0.161 0.000
H65-H75 Diseases of middle ear and mastoid
0.839 0.161 0.000
Chapter VI Diseases of the nervous system
0.838 0.162 0.000
I87 Other disorders of veins
0.836 0.164 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.836 0.164 0.000
S20-S29 Injuries to the thorax
0.834 0.166 0.000
M25.7 Osteophyte
0.834 0.166 0.000
S80-S89 Injuries to the knee and lower leg
0.833 0.167 0.000
M24 Other specific joint derangements
0.832 0.168 0.000
M15-M19 Arthrosis
0.832 0.168 0.000
H44 Disorders of globe
0.831 0.169 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.830 0.170 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.829 0.171 0.000
M40-M43 Deforming dorsopathies
0.828 0.172 0.000
A49 Bacterial infection of unspecified site
0.827 0.173 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.827 0.173 0.000
H53.4 Visual field defects
0.826 0.174 0.000
L20-L30 Dermatitis and eczema
0.825 0.175 0.000
H54 Blindness and low vision
0.824 0.176 0.000
M51.8 Other specified intervertebral disk disorders
0.823 0.177 0.000
L50-L54 Urticaria and erythema
0.822 0.178 0.000
M79.66 Pain in limb (Lower leg)
0.817 0.183 0.000
H53.0 Amblyopia ex anopsia
0.814 0.186 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.813 0.187 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.813 0.187 0.000
I38 Endocarditis, valve unspecified
0.811 0.189 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.810 0.190 0.000
M25.46 Effusion of joint (Lower leg)
0.809 0.191 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.809 0.191 0.000
M79.0 Rheumatism, unspecified
0.809 0.191 0.000
M31.6 Other giant cell arteritis
0.806 0.194 0.000
J38.3 Other diseases of vocal cords
0.805 0.195 0.000
S10-S19 Injuries to the neck
0.805 0.195 0.000
L40-L45 Papulosquamous disorders
0.800 0.200 0.000
H44.2 Degenerative myopia
0.800 0.200 0.000
T51 Toxic effect of alcohol
0.799 0.201 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.799 0.201 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.799 0.201 0.000
M33 Dermatopolymyositis
0.796 0.204 0.000
I61 Intracerebral haemorrhage
0.796 0.204 0.000
T66-T78 Other and unspecified effects of external causes
0.791 0.209 0.000
M79.7 Fibromyalgia
0.790 0.210 0.000
A00-A09 Intestinal infectious diseases
0.789 0.211 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.788 0.212 0.000
H53.2 Diplopia
0.787 0.213 0.000
D70 Agranulocytosis
0.786 0.214 0.000
B35-B49 Mycoses
0.784 0.215 0.000
I65.2 Occlusion and stenosis of carotid artery
0.784 0.216 0.000
B18 Chronic viral hepatitis
0.784 0.216 0.000
F17.2 Dependence syndrome
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.783 0.217 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.781 0.219 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.781 0.219 0.000
B95-B98 Bacterial, viral and other infectious agents
0.780 0.220 0.000
J32.9 Chronic sinusitis, unspecified
0.780 0.220 0.000
J33 Nasal polyp
0.779 0.221 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.778 0.222 0.000
J39 Other diseases of upper respiratory tract
0.778 0.222 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.777 0.223 0.000
F10.0 Acute intoxication
0.777 0.223 0.000
F60-F69 Disorders of adult personality and behaviour
0.777 0.223 0.000
S64 Injury of nerves at wrist and hand level
0.776 0.224 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.775 0.225 0.000
F10.3 Withdrawal state
0.774 0.226 0.000
I25 Chronic ischaemic heart disease
0.774 0.226 0.000
M50 Cervical disk disorders
0.774 0.226 0.000
M25.57 Pain in joint (Ankle and foot)
0.774 0.226 0.000
I67.9 Cerebrovascular disease, unspecified
0.773 0.227 0.000
I80 Phlebitis and thrombophlebitis
0.771 0.229 0.000
M25.77 Osteophyte (Ankle and foot)
0.770 0.230 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.769 0.231 0.000
H60-H62 Diseases of external ear
0.768 0.232 0.000
A41 Other septicaemia
0.768 0.232 0.000
F80-F89 Disorders of psychological development
0.765 0.235 0.000
M79.8 Other specified soft tissue disorders
0.764 0.236 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.761 0.239 0.000
S40-S49 Injuries to the shoulder and upper arm
0.761 0.239 0.000
I70 Atherosclerosis
0.761 0.239 0.000
I50.9 Heart failure, unspecified
0.759 0.241 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.757 0.242 0.000
S02 Fracture of skull and facial bones
0.757 0.243 0.000
H55-H59 Other disorders of eye and adnexa
0.756 0.244 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.756 0.244 0.000
I50.1 Left ventricular failure
0.752 0.248 0.000
M25.53 Pain in joint (Forearm)
0.751 0.249 0.000
H54.9 Unspecified visual impairment (binocular)
0.750 0.250 0.000
M54.4 Lumbago with sciatica
0.750 0.250 0.000
M21 Other acquired deformities of limbs
0.750 0.250 0.000
M54.56 Low back pain (Lumbar region)
0.750 0.250 0.000
I77 Other disorders of arteries and arterioles
0.750 0.250 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.749 0.251 0.000
Chapter XXII Codes for special purposes
0.748 0.251 0.000
M25.54 Pain in joint (Hand)
0.748 0.252 0.000
M06.0 Seronegative rheumatoid arthritis
0.746 0.254 0.000
M13 Other arthritis
0.746 0.254 0.000
I42 Cardiomyopathy
0.745 0.254 0.000
I72 Other aneurysm
0.745 0.255 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.745 0.255 0.000
S65 Injury of blood vessels at wrist and hand level
0.744 0.256 0.000
G90-G99 Other disorders of the nervous system
0.743 0.257 0.000
T51.0 Ethanol
0.742 0.257 0.000
T40.2 Other opioids
0.741 0.259 0.000
I22 Subsequent myocardial infarction
0.740 0.260 0.000
M25.9 Joint disorder, unspecified
0.739 0.261 0.000
S80 Superficial injury of lower leg
0.739 0.261 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.738 0.262 0.000
M91-M94 Chondropathies
0.738 0.262 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.737 0.263 0.000
I62 Other nontraumatic intracranial haemorrhage
0.737 0.263 0.000
I21 Acute myocardial infarction
0.736 0.264 0.000
I37 Pulmonary valve disorders
0.735 0.265 0.000
M77 Other enthesopathies
0.734 0.266 0.000
I25.2 Old myocardial infarction
0.733 0.267 0.000
I05-I09 Chronic rheumatic heart diseases
0.733 0.267 0.000
M19 Other arthrosis
0.731 0.269 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.730 0.270 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.729 0.271 0.000
S00.8 Superficial injury of other parts of head
0.729 0.271 0.000
M43 Other deforming dorsopathies
0.728 0.272 0.000
I35 Nonrheumatic aortic valve disorders
0.727 0.273 0.000
I78 Diseases of capillaries
0.727 0.273 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.725 0.275 0.000
I34 Nonrheumatic mitral valve disorders
0.724 0.276 0.000
J38.4 Oedema of larynx
0.724 0.276 0.000
F10.2 Dependence syndrome
0.724 0.276 0.000
L52 Erythema nodosum
0.722 0.277 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.722 0.278 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
T39.0 Salicylates
0.722 0.278 0.000
I46 Cardiac arrest
0.721 0.279 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.721 0.279 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.719 0.281 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.719 0.281 0.000
M22 Disorders of patella
0.719 0.281 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.718 0.282 0.000
M51.2 Other specified intervertebral disk displacement
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
J95-J99 Other diseases of the respiratory system
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M34 Systemic sclerosis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
S09 Other and unspecified injuries of head
0.713 0.287 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.712 0.287 0.000
B18.2 Chronic viral hepatitis C
0.712 0.288 0.000
I88 Nonspecific lymphadenitis
0.712 0.288 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.711 0.289 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.711 0.289 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.711 0.289 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.711 0.289 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.711 0.289 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.711 0.289 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.711 0.289 0.000
F11 Mental and behavioural disorders due to use of opioids
0.711 0.289 0.000
M53 Other dorsopathies, not elsewhere classified
0.711 0.289 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.709 0.290 0.000
B99-B99 Other infectious diseases
0.709 0.291 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.291 0.000
B65-B83 Helminthiases
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.709 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.291 0.000
A75-A79 Rickettsioses
0.709 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.291 0.000
A65-A69 Other spirochaetal diseases
0.709 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.291 0.000
A15-A19 Tuberculosis
0.709 0.291 0.000
F10.4 Withdrawal state with delirium
0.708 0.291 0.000
M25.3 Other instability of joint
0.707 0.292 0.000
M25.2 Flail joint
0.707 0.292 0.000
M25.1 Fistula of joint
0.707 0.292 0.000
M25.0 Haemarthrosis
0.707 0.292 0.000
A40 Streptococcal septicaemia
0.707 0.293 0.000
I82 Other venous embolism and thrombosis
0.706 0.293 0.000
H90-H95 Other disorders of ear
0.706 0.294 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.706 0.294 0.000
S70-S79 Injuries to the hip and thigh
0.706 0.294 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.705 0.295 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.704 0.295 0.000
T86 Failure and rejection of transplanted organs and tissues
0.704 0.296 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.703 0.297 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.702 0.298 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.702 0.298 0.000
M54.8 Other dorsalgia
0.702 0.298 0.000
M54.0 Panniculitis affecting regions of neck and back
0.702 0.298 0.000
T42.4 Benzodiazepines
0.702 0.298 0.000
H73 Other disorders of tympanic membrane
0.701 0.299 0.000
H71 Cholesteatoma of middle ear
0.701 0.299 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.700 0.300 0.000
M25.8 Other specified joint disorders
0.699 0.301 0.000
M54.6 Pain in thoracic spine
0.699 0.301 0.000
J33.8 Other polyp of sinus
0.699 0.301 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.698 0.302 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.698 0.302 0.000
S61 Open wound of wrist and hand
0.697 0.302 0.000
B17 Other acute viral hepatitis
0.695 0.304 0.000
M14 Arthropathies in other diseases classified elsewhere
0.695 0.305 0.000
M12 Other specific arthropathies
0.695 0.305 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.695 0.305 0.000
M08 Juvenile arthritis
0.695 0.305 0.000
A49.8 Other bacterial infections of unspecified site
0.694 0.306 0.000
A80-A89 Viral infections of the central nervous system
0.694 0.306 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.693 0.306 0.000
M79.60 Pain in limb (Multiple sites)
0.692 0.308 0.000
M25.47 Effusion of joint (Ankle and foot)
0.692 0.308 0.000
S64.4 Injury of digital nerve of other finger
0.692 0.308 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.691 0.308 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.308 0.000
I48 Atrial fibrillation and flutter
0.691 0.308 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.308 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.308 0.000
I40 Acute myocarditis
0.691 0.308 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.308 0.000
I36 Nonrheumatic tricuspid valve disorders
0.691 0.308 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.308 0.000
M76 Enthesopathies of lower limb, excluding foot
0.691 0.309 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.691 0.309 0.000
B25-B34 Other viral diseases
0.690 0.310 0.000
I67.2 Cerebral atherosclerosis
0.690 0.310 0.000
F32 Depressive episode
0.689 0.311 0.000
D73 Diseases of spleen
0.689 0.311 0.000
J39.8 Other specified diseases of upper respiratory tract
0.689 0.311 0.000
F17.9 Unspecified mental and behavioural disorder
0.689 0.311 0.000
F17.8 Other mental and behavioural disorders
0.689 0.311 0.000
F17.7 Residual and late-onset psychotic disorder
0.689 0.311 0.000
F17.6 Amnesic syndrome
0.689 0.311 0.000
F17.5 Psychotic disorder
0.689 0.311 0.000
F17.4 Withdrawal state with delirium
0.689 0.311 0.000
F17.3 Withdrawal state
0.689 0.311 0.000
F17.0 Acute intoxication
0.689 0.311 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.688 0.312 0.000
M54.55 Low back pain (Thoracolumbar region)
0.688 0.312 0.000
M54.54 Low back pain-Thoracic
0.688 0.312 0.000
M54.53 Low back pain-Cervicothoracic
0.688 0.312 0.000
M54.52 Low back pain-Cervical
0.688 0.312 0.000
M54.51 Low back pain-Occipit-atl-axl
0.688 0.312 0.000
M54.50 Low back pain (Multiple sites in spine)
0.688 0.312 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.688 0.312 0.000
L40 Psoriasis
0.686 0.314 0.000
T39.1 4-Aminophenol derivatives
0.686 0.314 0.000
I30 Acute pericarditis
0.685 0.315 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.685 0.315 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.685 0.315 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.684 0.316 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.684 0.316 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.684 0.316 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.684 0.316 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.684 0.316 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.684 0.316 0.000
T36 Poisoning by systemic antibiotics
0.684 0.316 0.000
M06.8 Other specified rheumatoid arthritis
0.683 0.317 0.000
M06.4 Inflammatory polyarthropathy
0.683 0.317 0.000
M06.3 Rheumatoid nodule
0.683 0.317 0.000
M06.2 Rheumatoid bursitis
0.683 0.317 0.000
M06.1 Adult-onset Still's disease
0.683 0.317 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.682 0.318 0.000
M25.59 Pain in joint (Site unspecified)
0.680 0.319 0.000
M25.58 Pain in joint (Other)
0.680 0.319 0.000
M25.52 Pain in joint (Upper arm)
0.680 0.319 0.000
M79.79 Fibromyalgia (Site unspecified)
0.680 0.320 0.000
J38.7 Other diseases of larynx
0.680 0.320 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.680 0.320 0.000
F10.9 Unspecified mental and behavioural disorder
0.680 0.320 0.000
F10.8 Other mental and behavioural disorders
0.680 0.320 0.000
F10.7 Residual and late-onset psychotic disorder
0.680 0.320 0.000
F10.6 Amnesic syndrome
0.680 0.320 0.000
F10.5 Psychotic disorder
0.680 0.320 0.000
M79.61 Pain in limb (Shoulder region)
0.680 0.320 0.000
I45.9 Conduction disorder, unspecified
0.679 0.321 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.678 0.322 0.000
L27 Dermatitis due to substances taken internally
0.678 0.322 0.000
I45.1 Other and unspecified right bundle-branch block
0.678 0.322 0.000
S90-S99 Injuries to the ankle and foot
0.677 0.323 0.000
I69 Sequelae of cerebrovascular disease
0.677 0.323 0.000
M79.5 Residual foreign body in soft tissue
0.676 0.324 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.676 0.324 0.000
M05 Seropositive rheumatoid arthritis
0.676 0.324 0.000
I74 Arterial embolism and thrombosis
0.676 0.324 0.000
M79.9 Soft tissue disorder, unspecified
0.676 0.324 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.676 0.324 0.000
M79.3 Panniculitis, unspecified
0.676 0.324 0.000
M79.2 Neuralgia and neuritis, unspecified
0.676 0.324 0.000
M79.1 Myalgia
0.676 0.324 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.675 0.325 0.000
L10-L14 Bullous disorders
0.675 0.325 0.000
J30 Vasomotor and allergic rhinitis
0.674 0.325 0.000
S08 Traumatic amputation of part of head
0.674 0.326 0.000
S07 Crushing injury of head
0.674 0.326 0.000
S05 Injury of eye and orbit
0.674 0.326 0.000
S04 Injury of cranial nerves
0.674 0.326 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.674 0.326 0.000
M80-M85 Disorders of bone density and structure
0.674 0.326 0.000
I42.0 Dilated cardiomyopathy
0.674 0.326 0.000
H53.1 Subjective visual disturbances
0.673 0.327 0.000
F99-F99 Unspecified mental disorder
0.673 0.327 0.000
H10-H13 Disorders of conjunctiva
0.673 0.327 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.672 0.327 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.672 0.327 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.672 0.327 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.672 0.327 0.000
M10 Gout
0.672 0.328 0.000
Chapter XX External causes of morbidity and mortality
0.671 0.329 0.000
I73 Other peripheral vascular diseases
0.670 0.330 0.000
G70-G73 Diseases of myoneural junction and muscle
0.670 0.330 0.000
M79.64 Pain in limb (Hand)
0.669 0.331 0.000
M72 Fibroblastic disorders
0.668 0.332 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.668 0.332 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.668 0.332 0.000
L60-L75 Disorders of skin appendages
0.668 0.332 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.667 0.333 0.000
A49.0 Staphylococcal infection, unspecified
0.667 0.333 0.000
F41 Other anxiety disorders
0.667 0.333 0.000
I44 Atrioventricular and left bundle-branch block
0.666 0.334 0.000
I86 Varicose veins of other sites
0.663 0.337 0.000
F31 Bipolar affective disorder
0.662 0.338 0.000
J37 Chronic laryngitis and laryngotracheitis
0.662 0.338 0.000
A48 Other bacterial diseases, not elsewhere classified
0.662 0.338 0.000
A44 Bartonellosis
0.662 0.338 0.000
A43 Nocardiosis
0.662 0.338 0.000
A42 Actinomycosis
0.662 0.338 0.000
A39 Meningococcal infection
0.662 0.338 0.000
A37 Whooping cough
0.662 0.338 0.000
A36 Diphtheria
0.662 0.338 0.000
A32 Listeriosis
0.662 0.338 0.000
A31 Infection due to other mycobacteria
0.662 0.338 0.000
A30 Leprosy [Hansen's disease]
0.662 0.338 0.000
A46 Erysipelas
0.662 0.338 0.000
A38 Scarlet fever
0.662 0.338 0.000
A35 Other tetanus
0.662 0.338 0.000
A34 Obstetrical tetanus
0.662 0.338 0.000
A33 Tetanus neonatorum
0.662 0.338 0.000
S32 Fracture of lumbar spine and pelvis
0.661 0.339 0.000
S00.1 Contusion of eyelid and periocular area
0.661 0.339 0.000
M71 Other bursopathies
0.661 0.339 0.000
M25.78 Osteophyte (Other)
0.661 0.339 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.660 0.340 0.000
I31 Other diseases of pericardium
0.660 0.340 0.000
F43 Reaction to severe stress, and adjustment disorders
0.660 0.340 0.000
D75 Other diseases of blood and blood-forming organs
0.660 0.340 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.660 0.340 0.000
M75 Shoulder lesions
0.660 0.340 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.658 0.342 0.000
H53.6 Night blindness
0.657 0.343 0.000
H53.5 Colour vision deficiencies
0.657 0.343 0.000
H53.3 Other disorders of binocular vision
0.657 0.343 0.000
F22 Persistent delusional disorders
0.657 0.343 0.000
G20-G26 Extrapyramidal and movement disorders
0.657 0.343 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.656 0.344 0.000
M51.3 Other specified intervertebral disk degeneration
0.656 0.344 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.656 0.344 0.000
M51.9 Intervertebral disk disorder, unspecified
0.656 0.344 0.000
M51.4 Schmorl's nodes
0.656 0.344 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.656 0.344 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.655 0.344 0.000
F45 Somatoform disorders
0.654 0.346 0.000
M33.1 Other dermatomyositis
0.654 0.346 0.000
H18 Other disorders of cornea
0.653 0.347 0.000
I33 Acute and subacute endocarditis
0.653 0.347 0.000
I25.5 Ischaemic cardiomyopathy
0.652 0.348 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.651 0.348 0.000
Q50-Q56 Congenital malformations of genital organs
0.651 0.349 0.000
I77.1 Stricture of artery
0.651 0.349 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.650 0.349 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.650 0.349 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.650 0.349 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.650 0.349 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.650 0.349 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.650 0.349 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.650 0.349 0.000
F29 Unspecified nonorganic psychosis
0.650 0.350 0.000
J32.0 Chronic maxillary sinusitis
0.650 0.350 0.000
J00-J06 Acute upper respiratory infections
0.650 0.350 0.000
A49.1 Streptococcal infection, unspecified
0.649 0.351 0.000
Q60-Q64 Congenital malformations of the urinary system
0.649 0.351 0.000
H91 Other hearing loss
0.649 0.351 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.649 0.351 0.000
M07 Psoriatic and enteropathic arthropathies
0.649 0.351 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.648 0.352 0.000
S61.0 Open wound of finger(s) without damage to nail
0.647 0.353 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.647 0.353 0.000
J38.1 Polyp of vocal cord and larynx
0.646 0.354 0.000
J35 Chronic diseases of tonsils and adenoids
0.646 0.354 0.000
E10-E14 Diabetes mellitus
0.645 0.355 0.000
I45.5 Other specified heart block
0.645 0.355 0.000
M50.1 Cervical disk disorder with radiculopathy
0.644 0.356 0.000
I23 Certain current complications following acute myocardial infarction
0.644 0.356 0.000
S00.3 Superficial injury of nose
0.644 0.356 0.000
L50 Urticaria
0.643 0.357 0.000
M54.1 Radiculopathy
0.642 0.358 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.642 0.358 0.000
S69 Other and unspecified injuries of wrist and hand
0.641 0.358 0.000
M24.1 Other articular cartilage disorders
0.641 0.358 0.000
M35 Other systemic involvement of connective tissue
0.641 0.358 0.000
T78 Adverse effects, not elsewhere classified
0.641 0.359 0.000
M18 Arthrosis of first carpometacarpal joint
0.641 0.359 0.000
S68 Traumatic amputation of wrist and hand
0.641 0.359 0.000
H61 Other disorders of external ear
0.641 0.359 0.000
M25.49 Effusion of joint (Site unspecified)
0.641 0.359 0.000
M25.48 Effusion of joint (Other)
0.641 0.359 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.641 0.359 0.000
M25.44 Effusion of joint (Hand)
0.641 0.359 0.000
M25.43 Effusion of joint (Forearm)
0.641 0.359 0.000
M25.42 Effusion of joint (Upper arm)
0.641 0.359 0.000
M25.41 Effusion of joint (Shoulder region)
0.641 0.359 0.000
M25.40 Effusion of joint (Multiple sites)
0.641 0.359 0.000
L30 Other dermatitis
0.640 0.360 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.638 0.362 0.000
B37 Candidiasis
0.638 0.362 0.000
S81 Open wound of lower leg
0.638 0.362 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.638 0.362 0.000
S00.7 Multiple superficial injuries of head
0.638 0.362 0.000
S00.5 Superficial injury of lip and oral cavity
0.638 0.362 0.000
S00.4 Superficial injury of ear
0.638 0.362 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.638 0.362 0.000
M11 Other crystal arthropathies
0.638 0.362 0.000
J36 Peritonsillar abscess
0.637 0.363 0.000
J32.8 Other chronic sinusitis
0.637 0.363 0.000
S12 Fracture of neck
0.636 0.364 0.000
S65.5 Injury of blood vessel(s) of other finger
0.636 0.364 0.000
J60-J70 Lung diseases due to external agents
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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