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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77541621
log Bayes Factor = 26.0542
Chromosome 8   position 128,077,146  (GRCh37) Explore rs77541621 on Ensembl!
Variant rs77541621 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C61 Malignant neoplasm of prostate
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C60-C63 Malignant neoplasms of male genital organs
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.986 0.014 0.000
S00-S09 Injuries to the head
0.984 0.016 0.000
C79 Secondary malignant neoplasm of other sites
0.981 0.019 0.000
M45-M49 Spondylopathies
0.970 0.030 0.000
S40-S49 Injuries to the shoulder and upper arm
0.969 0.031 0.000
C15-C26 Malignant neoplasms of digestive organs
0.955 0.045 0.000
M20-M25 Other joint disorders
0.948 0.052 0.000
S00 Superficial injury of head
0.948 0.052 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.946 0.054 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.944 0.056 0.000
S60-S69 Injuries to the wrist and hand
0.930 0.070 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.928 0.072 0.000
Chapter VI Diseases of the nervous system
0.926 0.074 0.000
Chapter XX External causes of morbidity and mortality
0.919 0.081 0.000
M48 Other spondylopathies
0.908 0.092 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.900 0.100 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.900 0.100 0.000
O80-O84 Delivery
0.897 0.103 0.000
Chapter V Mental and behavioural disorders
0.893 0.107 0.000
S42 Fracture of shoulder and upper arm
0.890 0.110 0.000
O80 Single spontaneous delivery
0.876 0.124 0.000
C18 Malignant neoplasm of colon
0.874 0.126 0.000
M47 Spondylosis
0.873 0.127 0.000
O80.0 Spontaneous vertex delivery
0.862 0.138 0.000
M31 Other necrotising vasculopathies
0.858 0.142 0.000
Chapter I Certain infectious and parasitic diseases
0.857 0.143 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.857 0.143 0.000
C18.9 Colon, unspecified
0.851 0.149 0.000
M24 Other specific joint derangements
0.851 0.149 0.000
D00-D09 In situ neoplasms
0.851 0.149 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.844 0.156 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.843 0.157 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.842 0.158 0.000
S00.0 Superficial injury of scalp
0.841 0.159 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.841 0.159 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.839 0.161 0.000
M48.0 Spinal stenosis
0.839 0.161 0.000
A30-A49 Other bacterial diseases
0.836 0.164 0.000
S68 Traumatic amputation of wrist and hand
0.836 0.164 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.835 0.165 0.000
S90-S99 Injuries to the ankle and foot
0.833 0.167 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.831 0.169 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.829 0.171 0.000
C71 Malignant neoplasm of brain
0.828 0.172 0.000
T92 Sequelae of injuries of upper limb
0.826 0.174 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.825 0.175 0.000
Chapter XXII Codes for special purposes
0.825 0.175 0.000
S00.9 Superficial injury of head, part unspecified
0.822 0.178 0.000
M86-M90 Other osteopathies
0.821 0.179 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.820 0.180 0.000
A41 Other septicaemia
0.820 0.180 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.818 0.182 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.816 0.184 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.816 0.184 0.000
M47.8 Other spondylosis
0.816 0.184 0.000
M45 Ankylosing spondylitis
0.815 0.185 0.000
A41.9 Septicaemia, unspecified
0.814 0.186 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.808 0.192 0.000
M80-M85 Disorders of bone density and structure
0.808 0.192 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.806 0.194 0.000
G63.2 Diabetic polyneuropathy
0.804 0.196 0.000
S05 Injury of eye and orbit
0.803 0.197 0.000
S01 Open wound of head
0.800 0.200 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.797 0.203 0.000
T90 Sequelae of injuries of head
0.787 0.213 0.000
S41 Open wound of shoulder and upper arm
0.786 0.214 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.786 0.214 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.784 0.216 0.000
W00-W19 Falls
0.781 0.219 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.778 0.222 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.778 0.222 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.778 0.222 0.000
S80-S89 Injuries to the knee and lower leg
0.777 0.223 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.772 0.228 0.000
T93 Sequelae of injuries of lower limb
0.770 0.230 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.769 0.231 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.768 0.232 0.000
O00-O08 Pregnancy with abortive outcome
0.768 0.232 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.767 0.233 0.000
C18.4 Transverse colon
0.767 0.233 0.000
S00.1 Contusion of eyelid and periocular area
0.765 0.234 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.765 0.235 0.000
S42.2 Fracture of upper end of humerus
0.764 0.236 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.763 0.237 0.000
S50-S59 Injuries to the elbow and forearm
0.762 0.238 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.760 0.240 0.000
M40-M43 Deforming dorsopathies
0.758 0.242 0.000
G20-G26 Extrapyramidal and movement disorders
0.757 0.243 0.000
S42.0 Fracture of clavicle
0.757 0.243 0.000
S61 Open wound of wrist and hand
0.755 0.245 0.000
S02 Fracture of skull and facial bones
0.755 0.245 0.000
M34 Systemic sclerosis
0.754 0.245 0.000
M31.6 Other giant cell arteritis
0.754 0.246 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.752 0.248 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.751 0.248 0.000
M21 Other acquired deformities of limbs
0.751 0.249 0.000
V10-V19 Pedal cyclist injured in transport accident
0.750 0.249 0.000
G61 Inflammatory polyneuropathy
0.750 0.250 0.000
F03 Unspecified dementia
0.750 0.250 0.000
S40 Superficial injury of shoulder and upper arm
0.749 0.251 0.000
T42.4 Benzodiazepines
0.749 0.251 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.747 0.253 0.000
C15 Malignant neoplasm of oesophagus
0.747 0.253 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.743 0.257 0.000
M00-M03 Infectious arthropathies
0.742 0.258 0.000
R73 Elevated blood glucose level
0.742 0.258 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.742 0.258 0.000
C77.5 Intrapelvic lymph nodes
0.741 0.259 0.000
D04 Carcinoma in situ of skin
0.740 0.260 0.000
S60 Superficial injury of wrist and hand
0.740 0.260 0.000
S09 Other and unspecified injuries of head
0.739 0.261 0.000
G62 Other polyneuropathies
0.739 0.261 0.000
S65 Injury of blood vessels at wrist and hand level
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.739 0.261 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.739 0.261 0.000
R50-R69 General symptoms and signs
0.738 0.262 0.000
S42.3 Fracture of shaft of humerus
0.738 0.262 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.737 0.262 0.000
M60-M63 Disorders of muscles
0.737 0.263 0.000
C18.1 Appendix
0.737 0.263 0.000
T45.2 Vitamins, not elsewhere classified
0.736 0.264 0.000
S32 Fracture of lumbar spine and pelvis
0.733 0.267 0.000
F30-F39 Mood [affective] disorders
0.732 0.267 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.732 0.268 0.000
T66-T78 Other and unspecified effects of external causes
0.730 0.270 0.000
C80 Malignant neoplasm without specification of site
0.728 0.272 0.000
M48.02 Spinal stenosis (Cervical region)
0.727 0.272 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.726 0.274 0.000
C71.8 Overlapping lesion of brain
0.723 0.277 0.000
V20-V29 Motorcycle rider injured in transport accident
0.723 0.277 0.000
D06 Carcinoma in situ of cervix uteri
0.722 0.278 0.000
C64-C68 Malignant neoplasms of urinary tract
0.722 0.278 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.722 0.278 0.000
M05-M14 Inflammatory polyarthropathies
0.721 0.279 0.000
S01.5 Open wound of lip and oral cavity
0.720 0.280 0.000
M23 Internal derangement of knee
0.719 0.281 0.000
M48.06 Spinal stenosis (Lumbar region)
0.719 0.281 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.718 0.282 0.000
X60-X84 Intentional self-harm
0.717 0.283 0.000
C79.6 Secondary malignant neoplasm of ovary
0.717 0.283 0.000
C77.4 Inguinal and lower limb lymph nodes
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.717 0.283 0.000
C60 Malignant neoplasm of penis
0.717 0.283 0.000
C71.9 Brain, unspecified
0.716 0.284 0.000
M25 Other joint disorders, not elsewhere classified
0.715 0.285 0.000
M47.1 Other spondylosis with myelopathy
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.712 0.288 0.000
C77.9 Lymph node, unspecified
0.711 0.289 0.000
T91 Sequelae of injuries of neck and trunk
0.710 0.289 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.710 0.290 0.000
S01.2 Open wound of nose
0.710 0.290 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.708 0.292 0.000
R73.9 Hyperglycaemia, unspecified
0.708 0.292 0.000
S61.0 Open wound of finger(s) without damage to nail
0.707 0.292 0.000
R53 Malaise and fatigue
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
C79.2 Secondary malignant neoplasm of skin
0.707 0.293 0.000
S08 Traumatic amputation of part of head
0.705 0.294 0.000
S07 Crushing injury of head
0.705 0.294 0.000
S04 Injury of cranial nerves
0.705 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.705 0.294 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.705 0.295 0.000
M91-M94 Chondropathies
0.704 0.296 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.704 0.296 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.704 0.296 0.000
X10-X19 Contact with heat and hot substances
0.704 0.296 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.703 0.297 0.000
M65-M68 Disorders of synovium and tendon
0.702 0.297 0.000
C01 Malignant neoplasm of base of tongue
0.702 0.298 0.000
S06 Intracranial injury
0.701 0.299 0.000
C26.0 Intestinal tract, part unspecified
0.699 0.301 0.000
O03 Spontaneous abortion
0.699 0.301 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.697 0.303 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.697 0.303 0.000
C78.0 Secondary malignant neoplasm of lung
0.697 0.303 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.697 0.303 0.000
M49 Spondylopathies in diseases classified elsewhere
0.696 0.304 0.000
S48 Traumatic amputation of shoulder and upper arm
0.695 0.305 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.695 0.305 0.000
S44 Injury of nerves at shoulder and upper arm level
0.695 0.305 0.000
S47 Crushing injury of shoulder and upper arm
0.695 0.305 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.694 0.305 0.000
R79 Other abnormal findings of blood chemistry
0.694 0.306 0.000
Y00-Y09 Assault
0.693 0.307 0.000
S00.8 Superficial injury of other parts of head
0.692 0.308 0.000
A40 Streptococcal septicaemia
0.691 0.309 0.000
M84 Disorders of continuity of bone
0.690 0.310 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.689 0.311 0.000
O85-O92 Complications predominantly related to the puerperium
0.688 0.311 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.687 0.313 0.000
R45 Symptoms and signs involving emotional state
0.687 0.313 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.687 0.313 0.000
V40-V49 Car occupant injured in transport accident
0.686 0.314 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.686 0.314 0.000
R52 Pain, not elsewhere classified
0.686 0.314 0.000
C21 Malignant neoplasm of anus and anal canal
0.685 0.315 0.000
C17 Malignant neoplasm of small intestine
0.685 0.315 0.000
C23 Malignant neoplasm of gallbladder
0.685 0.315 0.000
C77.8 Lymph nodes of multiple regions
0.683 0.317 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.681 0.319 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.681 0.319 0.000
M24.1 Other articular cartilage disorders
0.681 0.319 0.000
S64 Injury of nerves at wrist and hand level
0.680 0.320 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.680 0.320 0.000
M33 Dermatopolymyositis
0.680 0.320 0.000
M32 Systemic lupus erythematosus
0.680 0.320 0.000
M30 Polyarteritis nodosa and related conditions
0.680 0.320 0.000
S00.7 Multiple superficial injuries of head
0.680 0.320 0.000
S00.5 Superficial injury of lip and oral cavity
0.680 0.320 0.000
S00.4 Superficial injury of ear
0.680 0.320 0.000
M48.09 Spinal stenosis (Site unspecified)
0.678 0.322 0.000
T98 Sequelae of other and unspecified effects of external causes
0.677 0.323 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.323 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.677 0.323 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
S90 Superficial injury of ankle and foot
0.675 0.325 0.000
S81 Open wound of lower leg
0.675 0.325 0.000
S20-S29 Injuries to the thorax
0.674 0.325 0.000
W19 Unspecified fall
0.674 0.326 0.000
G90-G99 Other disorders of the nervous system
0.673 0.327 0.000
M50-M54 Other dorsopathies
0.673 0.327 0.000
S42.20 Fracture of upper end of humerus (closed)
0.673 0.327 0.000
F60-F69 Disorders of adult personality and behaviour
0.673 0.327 0.000
V80-V89 Other land transport accidents
0.672 0.328 0.000
M47.82 Other spondylosis (Cervical region)
0.671 0.329 0.000
G12 Spinal muscular atrophy and related syndromes
0.671 0.329 0.000
S69 Other and unspecified injuries of wrist and hand
0.669 0.330 0.000
G60 Hereditary and idiopathic neuropathy
0.669 0.331 0.000
S31 Open wound of abdomen, lower back and pelvis
0.669 0.331 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.669 0.331 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.668 0.332 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.668 0.332 0.000
M35 Other systemic involvement of connective tissue
0.667 0.333 0.000
S32.5 Fracture of pubis
0.666 0.334 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.665 0.335 0.000
F01 Vascular dementia
0.664 0.336 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.664 0.336 0.000
B99-B99 Other infectious diseases
0.664 0.336 0.000
S67 Crushing injury of wrist and hand
0.662 0.338 0.000
S42.00 Fracture of clavicle (closed)
0.661 0.339 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.659 0.341 0.000
Y35-Y36 Legal intervention and operations of war
0.659 0.341 0.000
Y10-Y34 Event of undetermined intent
0.659 0.341 0.000
X85-X99 Assault
0.659 0.341 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.659 0.341 0.000
X50-X57 Overexertion, travel and privation
0.659 0.341 0.000
X30-X39 Exposure to forces of nature
0.659 0.341 0.000
X20-X29 Contact with venomous animals and plants
0.659 0.341 0.000
X00-X09 Exposure to smoke, fire and flames
0.659 0.341 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.659 0.341 0.000
W75-W84 Other accidental threats to breathing
0.659 0.341 0.000
W65-W74 Accidental drowning and submersion
0.659 0.341 0.000
W50-W64 Exposure to animate mechanical forces
0.659 0.341 0.000
V98-V99 Other and unspecified transport accidents
0.659 0.341 0.000
V95-V97 Air and space transport accidents
0.659 0.341 0.000
V90-V94 Water transport accidents
0.659 0.341 0.000
V70-V79 Bus occupant injured in transport accident
0.659 0.341 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.659 0.341 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.659 0.341 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.659 0.341 0.000
V01-V09 Pedestrian injured in transport accident
0.659 0.341 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.659 0.341 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.658 0.342 0.000
Q80-Q89 Other congenital malformations
0.657 0.343 0.000
S70-S79 Injuries to the hip and thigh
0.656 0.344 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.655 0.344 0.000
S41.1 Open wound of upper arm
0.654 0.345 0.000
M24.5 Contracture of joint
0.654 0.346 0.000
M47.89 Other spondylosis (Site unspecified)
0.654 0.346 0.000
F99-F99 Unspecified mental disorder
0.653 0.347 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.653 0.347 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.652 0.348 0.000
R52.1 Chronic intractable pain
0.651 0.349 0.000
M48.9 Spondylopathy, unspecified
0.651 0.349 0.000
M48.8 Other specified spondylopathies
0.651 0.349 0.000
M48.4 Fatigue fracture of vertebra
0.651 0.349 0.000
M48.3 Traumatic spondylopathy
0.651 0.349 0.000
M48.2 Kissing spine
0.651 0.349 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.651 0.349 0.000
G70-G73 Diseases of myoneural junction and muscle
0.650 0.350 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.649 0.351 0.000
T92.1 Sequelae of fracture of arm
0.648 0.352 0.000
R45.1 Restlessness and agitation
0.648 0.352 0.000
M90 Osteopathies in diseases classified elsewhere
0.646 0.354 0.000
G64 Other disorders of peripheral nervous system
0.645 0.355 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.645 0.355 0.000
C70 Malignant neoplasm of meninges
0.645 0.355 0.000
C69 Malignant neoplasm of eye and adnexa
0.645 0.355 0.000
M46 Other inflammatory spondylopathies
0.644 0.356 0.000
Q50-Q56 Congenital malformations of genital organs
0.644 0.356 0.000
O84 Multiple delivery
0.643 0.357 0.000
O83 Other assisted single delivery
0.643 0.357 0.000
O81 Single delivery by forceps and vacuum extractor
0.643 0.357 0.000
G61.0 Guillain-Barre syndrome
0.643 0.357 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.642 0.358 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.642 0.358 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.642 0.358 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.642 0.358 0.000
S05.1 Contusion of eyeball and orbital tissues
0.642 0.358 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.640 0.360 0.000
F70-F79 Mental retardation
0.640 0.360 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.639 0.361 0.000
W19.4 Street and highway
0.639 0.361 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.639 0.361 0.000
R23 Other skin changes
0.638 0.362 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.638 0.362 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.638 0.362 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.638 0.362 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.637 0.362 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.637 0.363 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.636 0.363 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.636 0.364 0.000
M86 Osteomyelitis
0.636 0.364 0.000
S62 Fracture at wrist and hand level
0.635 0.365 0.000
R60 Oedema, not elsewhere classified
0.635 0.365 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.633 0.367 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.632 0.368 0.000
R56 Convulsions, not elsewhere classified
0.632 0.368 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.631 0.369 0.000
S00.3 Superficial injury of nose
0.630 0.370 0.000
O03.9 Complete or unspecified, without complication
0.630 0.370 0.000
D06.9 Cervix, unspecified
0.630 0.370 0.000
T40.2 Other opioids
0.630 0.370 0.000
S42.30 Fracture of shaft of humerus (closed)
0.630 0.370 0.000
S02.1 Fracture of base of skull
0.630 0.370 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.630 0.370 0.000
G25 Other extrapyramidal and movement disorders
0.629 0.371 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.628 0.372 0.000
O80.8 Other single spontaneous delivery
0.628 0.372 0.000
O80.1 Spontaneous breech delivery
0.628 0.372 0.000
O82 Single delivery by Caesarean section
0.628 0.372 0.000
M88 Paget's disease of bone [osteitis deformans]
0.627 0.373 0.000
C18.8 Overlapping lesion of colon
0.626 0.374 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.626 0.374 0.000
B65-B83 Helminthiases
0.626 0.374 0.000
W20-W49 Exposure to inanimate mechanical forces
0.626 0.374 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.625 0.375 0.000
M87 Osteonecrosis
0.625 0.375 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.624 0.376 0.000
M06 Other rheumatoid arthritis
0.624 0.376 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.624 0.376 0.000
G24 Dystonia
0.624 0.376 0.000
T43.2 Other and unspecified antidepressants
0.623 0.377 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.623 0.377 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.622 0.378 0.000
S91 Open wound of ankle and foot
0.621 0.379 0.000
S61.7 Multiple open wounds of wrist and hand
0.620 0.380 0.000
M24.0 Loose body in joint
0.620 0.380 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.619 0.381 0.000
S05.8 Other injuries of eye and orbit
0.619 0.381 0.000
S32.50 Fracture of pubis (closed)
0.619 0.381 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.616 0.384 0.000
M34.9 Systemic sclerosis, unspecified
0.616 0.384 0.000
D03 Melanoma in situ
0.616 0.384 0.000
M31.9 Necrotising vasculopathy, unspecified
0.615 0.384 0.000
M31.8 Other specified necrotising vasculopathies
0.615 0.384 0.000
M31.7 Microscopic polyangiitis
0.615 0.384 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.615 0.384 0.000
M31.3 Wegener's granulomatosis
0.615 0.384 0.000
M31.2 Lethal midline granuloma
0.615 0.384 0.000
M31.1 Thrombotic microangiopathy
0.615 0.384 0.000
M31.0 Hypersensitivity angiitis
0.615 0.384 0.000
R21 Rash and other nonspecific skin eruption
0.615 0.385 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.615 0.385 0.000
B50-B64 Protozoal diseases
0.615 0.385 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.615 0.385 0.000
A75-A79 Rickettsioses
0.615 0.385 0.000
A70-A74 Other diseases caused by chlamydiae
0.615 0.385 0.000
A65-A69 Other spirochaetal diseases
0.615 0.385 0.000
A20-A28 Certain zoonotic bacterial diseases
0.615 0.385 0.000
A15-A19 Tuberculosis
0.615 0.385 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.615 0.385 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.614 0.386 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.614 0.386 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.614 0.386 0.000
T42.3 Barbiturates
0.614 0.386 0.000
T42.2 Succinimides and oxazolidinediones
0.614 0.386 0.000
T42.1 Iminostilbenes
0.614 0.386 0.000
T42.0 Hydantoin derivatives
0.614 0.386 0.000
S51 Open wound of forearm
0.613 0.387 0.000
G62.9 Polyneuropathy, unspecified
0.612 0.388 0.000
B35-B49 Mycoses
0.612 0.388 0.000
B15-B19 Viral hepatitis
0.611 0.389 0.000
M24.9 Joint derangement, unspecified
0.610 0.390 0.000
M24.7 Protrusio acetabuli
0.610 0.390 0.000
M24.6 Ankylosis of joint
0.610 0.390 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.610 0.390 0.000
M24.2 Disorder of ligament
0.610 0.390 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.610 0.390 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.610 0.390 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.610 0.390 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.609 0.391 0.000
O20 Haemorrhage in early pregnancy
0.609 0.391 0.000
C15.5 Lower third of oesophagus
0.609 0.391 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.607 0.393 0.000
M43 Other deforming dorsopathies
0.606 0.393 0.000
F31 Bipolar affective disorder
0.606 0.394 0.000
D04.4 Skin of scalp and neck
0.605 0.395 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.605 0.395 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.605 0.395 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.605 0.395 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.605 0.395 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.605 0.395 0.000
G63.1 Polyneuropathy in neoplastic disease
0.605 0.395 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.605 0.395 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.605 0.395 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.605 0.395 0.000
T46.7 Peripheral vasodilators
0.605 0.395 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.605 0.395 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.605 0.395 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.605 0.395 0.000
T46.1 Calcium-channel blockers
0.605 0.395 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.605 0.395 0.000
F80-F89 Disorders of psychological development
0.604 0.395 0.000
M85 Other disorders of bone density and structure
0.604 0.396 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.604 0.396 0.000
S37 Injury of urinary and pelvic organs
0.604 0.396 0.000
S36 Injury of intra-abdominal organs
0.604 0.396 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.604 0.396 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.604 0.396 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.604 0.396 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.603 0.397 0.000
T45.8 Other primarily systemic and haematological agents
0.603 0.397 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.603 0.397 0.000
T45.6 Fibrinolysis-affecting drugs
0.603 0.397 0.000
T45.5 Anticoagulants
0.603 0.397 0.000
T45.4 Iron and its compounds
0.603 0.397 0.000
T45.3 Enzymes, not elsewhere classified
0.603 0.397 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.603 0.397 0.000
T45.0 Antiallergic and antiemetic drugs
0.603 0.397 0.000
S65.5 Injury of blood vessel(s) of other finger
0.602 0.398 0.000
W08 Fall involving other furniture
0.602 0.398 0.000
C22.1 Intrahepatic bile duct carcinoma
0.602 0.398 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.602 0.398 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.602 0.398 0.000
M48.04 Spinal stenosis (Thoracic region)
0.602 0.398 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.602 0.398 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.602 0.398 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.602 0.398 0.000
S19 Other and unspecified injuries of neck
0.601 0.398 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.601 0.398 0.000
C16 Malignant neoplasm of stomach
0.600 0.399 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.600 0.400 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.600 0.400 0.000
A48 Other bacterial diseases, not elsewhere classified
0.599 0.401 0.000
A44 Bartonellosis
0.599 0.401 0.000
A43 Nocardiosis
0.599 0.401 0.000
A42 Actinomycosis
0.599 0.401 0.000
A39 Meningococcal infection
0.599 0.401 0.000
A37 Whooping cough
0.599 0.401 0.000
A36 Diphtheria
0.599 0.401 0.000
A32 Listeriosis
0.599 0.401 0.000
A31 Infection due to other mycobacteria
0.599 0.401 0.000
A30 Leprosy [Hansen's disease]
0.599 0.401 0.000
A46 Erysipelas
0.599 0.401 0.000
A38 Scarlet fever
0.599 0.401 0.000
A35 Other tetanus
0.599 0.401 0.000
A34 Obstetrical tetanus
0.599 0.401 0.000
A33 Tetanus neonatorum
0.599 0.401 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.599 0.401 0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.599 0.401 0.000
S68.8 Traumatic amputation of other parts of wrist and hand
0.599 0.401 0.000
S68.4 Traumatic amputation of hand at wrist level
0.599 0.401 0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.599 0.401 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.599 0.401 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.599 0.401 0.000
C18.6 Descending colon
0.599 0.401 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.598 0.401 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.598 0.402 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.598 0.402 0.000
O80.9 Single spontaneous delivery, unspecified
0.598 0.402 0.000
B95-B98 Bacterial, viral and other infectious agents
0.598 0.402 0.000
A80-A89 Viral infections of the central nervous system
0.597 0.403 0.000
S99 Other and unspecified injuries of ankle and foot
0.597 0.403 0.000
S98 Traumatic amputation of ankle and foot
0.597 0.403 0.000
S97 Crushing injury of ankle and foot
0.597 0.403 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.597 0.403 0.000
S95 Injury of blood vessels at ankle and foot level
0.597 0.403 0.000
S94 Injury of nerves at ankle and foot level
0.597 0.403 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.597 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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