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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs328
log Bayes Factor = 4.32431
Chromosome 8   position 19,819,724  (GRCh37) Explore rs328 on Ensembl!
Variant rs328 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I21 Acute myocardial infarction
0.000 0.006 0.994
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.015 0.985
I24 Other acute ischaemic heart diseases
0.000 0.019 0.981
I21.9 Acute myocardial infarction, unspecified
0.000 0.053 0.947
I20 Angina pectoris
0.000 0.055 0.945
I22 Subsequent myocardial infarction
0.000 0.070 0.930
I24.8 Other forms of acute ischaemic heart disease
0.000 0.076 0.924
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.077 0.923
I20.9 Angina pectoris, unspecified
0.000 0.079 0.921
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.094 0.906
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.162 0.838
I25.2 Old myocardial infarction
0.000 0.168 0.832
E78.0 Pure hypercholesterolaemia
0.000 0.172 0.828
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.174 0.826
I25.4 Coronary artery aneurysm
0.000 0.179 0.821
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.182 0.818
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.184 0.816
E78.5 Hyperlipidaemia, unspecified
0.000 0.195 0.805
I20.0 Unstable angina
0.000 0.213 0.787
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.234 0.766
E78.2 Mixed hyperlipidaemia
0.000 0.266 0.734
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.278 0.722
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.287 0.713
E78.1 Pure hyperglyceridaemia
0.000 0.317 0.683
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.330 0.670
I24.1 Dressler's syndrome
0.000 0.333 0.667
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.334 0.666
I22.8 Subsequent myocardial infarction of other sites
0.000 0.345 0.655
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.380 0.620
I25.5 Ischaemic cardiomyopathy
0.000 0.389 0.611
E78.4 Other hyperlipidaemia
0.000 0.410 0.590
E78.6 Lipoprotein deficiency
0.000 0.413 0.587
E78.3 Hyperchylomicronaemia
0.000 0.413 0.587
I25.3 Aneurysm of heart
0.000 0.443 0.557
E78.8 Other disorders of lipoprotein metabolism
0.000 0.447 0.553
I20.1 Angina pectoris with documented spasm
0.000 0.483 0.517
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I20.8 Other forms of angina pectoris
0.000 0.508 0.492
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.515 0.484
I21.4 Acute subendocardial myocardial infarction
0.000 0.589 0.411
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.799 0.201
E70-E90 Metabolic disorders
0.000 0.933 0.067
I77 Other disorders of arteries and arterioles
0.000 0.940 0.060
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.941 0.059
I77.1 Stricture of artery
0.000 0.944 0.056
I71 Aortic aneurysm and dissection
0.000 0.945 0.055
I77.6 Arteritis, unspecified
0.000 0.948 0.052
E86 Volume depletion
0.000 0.948 0.052
E73 Lactose intolerance
0.000 0.949 0.051
I72 Other aneurysm
0.000 0.950 0.050
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.950 0.050
E74 Other disorders of carbohydrate metabolism
0.000 0.950 0.049
E83 Disorders of mineral metabolism
0.000 0.950 0.049
I77.8 Other specified disorders of arteries and arterioles
0.000 0.951 0.049
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.951 0.049
Chapter IX Diseases of the circulatory system
0.000 0.951 0.049
E84 Cystic fibrosis
0.000 0.952 0.048
E79 Disorders of purine and pyrimidine metabolism
0.000 0.952 0.048
E77 Disorders of glycoprotein metabolism
0.000 0.952 0.048
E76 Disorders of glycosaminoglycan metabolism
0.000 0.952 0.048
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.952 0.048
E72 Other disorders of amino-acid metabolism
0.000 0.952 0.048
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.952 0.048
E70 Disorders of aromatic amino-acid metabolism
0.000 0.952 0.048
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.952 0.048
E83.1 Disorders of iron metabolism
0.000 0.952 0.048
E88 Other metabolic disorders
0.000 0.952 0.048
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.952 0.048
I70 Atherosclerosis
0.000 0.953 0.047
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.954 0.046
I72.4 Aneurysm of artery of lower extremity
0.000 0.955 0.045
E85 Amyloidosis
0.000 0.955 0.045
I77.5 Necrosis of artery
0.000 0.957 0.043
I77.4 Coeliac artery compression syndrome
0.000 0.957 0.043
I77.3 Arterial fibromuscular dysplasia
0.000 0.957 0.043
I77.2 Rupture of artery
0.000 0.957 0.043
I71.0 Dissection of aorta [any part]
0.000 0.957 0.043
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.957 0.043
I74 Arterial embolism and thrombosis
0.000 0.957 0.043
I72.3 Aneurysm of iliac artery
0.000 0.958 0.042
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.958 0.042
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.960 0.040
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.960 0.040
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.960 0.040
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.960 0.040
E73.9 Lactose intolerance, unspecified
0.000 0.961 0.039
I78 Diseases of capillaries
0.000 0.961 0.039
I77.0 Arteriovenous fistula, acquired
0.000 0.961 0.038
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.962 0.038
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.962 0.038
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.963 0.037
I72.8 Aneurysm of other specified arteries
0.000 0.963 0.037
E73.8 Other lactose intolerance
0.000 0.963 0.036
E73.1 Secondary lactase deficiency
0.000 0.963 0.036
E73.0 Congenital lactase deficiency
0.000 0.963 0.036
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.964 0.036
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.964 0.036
I72.1 Aneurysm of artery of upper extremity
0.000 0.964 0.036
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.964 0.036
I70.0 Atherosclerosis of aorta
0.000 0.964 0.036
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.964 0.036
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.964 0.036
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.964 0.036
E74.2 Disorders of galactose metabolism
0.000 0.964 0.036
E74.1 Disorders of fructose metabolism
0.000 0.964 0.036
E74.0 Glycogen storage disease
0.000 0.964 0.036
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.964 0.036
E83.8 Other disorders of mineral metabolism
0.000 0.964 0.036
E83.2 Disorders of zinc metabolism
0.000 0.964 0.036
E83.0 Disorders of copper metabolism
0.000 0.964 0.036
I72.2 Aneurysm of renal artery
0.000 0.965 0.035
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.965 0.035
I79.1 Aortitis in diseases classified elsewhere
0.000 0.965 0.035
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.965 0.035
I00-I02 Acute rheumatic fever
0.000 0.965 0.035
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.965 0.035
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.965 0.035
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.965 0.035
E70.3 Albinism
0.000 0.965 0.035
E70.2 Disorders of tyrosine metabolism
0.000 0.965 0.035
E70.1 Other hyperphenylalaninaemias
0.000 0.965 0.035
E70.0 Classical phenylketonuria
0.000 0.965 0.035
E71.3 Disorders of fatty-acid metabolism
0.000 0.965 0.035
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.965 0.035
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.965 0.035
E71.0 Maple-syrup-urine disease
0.000 0.965 0.035
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.965 0.035
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.965 0.035
E72.5 Disorders of glycine metabolism
0.000 0.965 0.035
E72.4 Disorders of ornithine metabolism
0.000 0.965 0.035
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.965 0.035
E72.2 Disorders of urea cycle metabolism
0.000 0.965 0.035
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.965 0.035
E72.0 Disorders of amino-acid transport
0.000 0.965 0.035
E75.6 Lipid storage disorder, unspecified
0.000 0.965 0.035
E75.5 Other lipid storage disorders
0.000 0.965 0.035
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.965 0.035
E75.3 Sphingolipidosis, unspecified
0.000 0.965 0.035
E75.2 Other sphingolipidosis
0.000 0.965 0.035
E75.1 Other gangliosidosis
0.000 0.965 0.035
E75.0 GM2 gangliosidosis
0.000 0.965 0.035
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.965 0.035
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.965 0.035
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.965 0.035
E76.2 Other mucopolysaccharidoses
0.000 0.965 0.035
E76.1 Mucopolysaccharidosis, type II
0.000 0.965 0.035
E76.0 Mucopolysaccharidosis, type I
0.000 0.965 0.035
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.965 0.035
E77.8 Other disorders of glycoprotein metabolism
0.000 0.965 0.035
E77.1 Defects in glycoprotein degradation
0.000 0.965 0.035
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.965 0.035
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.965 0.035
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.965 0.035
E79.1 Lesch-Nyhan syndrome
0.000 0.965 0.035
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.965 0.035
E83.4 Disorders of magnesium metabolism
0.000 0.965 0.035
E84.9 Cystic fibrosis, unspecified
0.000 0.965 0.035
E84.8 Cystic fibrosis with other manifestations
0.000 0.965 0.035
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.965 0.035
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.965 0.035
I72.9 Aneurysm of unspecified site
0.000 0.965 0.035
E88.9 Metabolic disorder, unspecified
0.000 0.965 0.034
E88.8 Other specified metabolic disorders
0.000 0.965 0.034
E88.3 Tumour lysis syndrome
0.000 0.965 0.034
E88.2 Lipomatosis, not elsewhere classified
0.000 0.965 0.034
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.965 0.034
I70.9 Generalised and unspecified atherosclerosis
0.000 0.966 0.034
I70.8 Atherosclerosis of other arteries
0.000 0.966 0.034
I70.1 Atherosclerosis of renal artery
0.000 0.966 0.034
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.966 0.034
I74.5 Embolism and thrombosis of iliac artery
0.000 0.966 0.034
E85.4 Organ-limited amyloidosis
0.000 0.967 0.033
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.967 0.033
E85.8 Other amyloidosis
0.000 0.968 0.032
E85.3 Secondary systemic amyloidosis
0.000 0.968 0.032
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.968 0.032
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.968 0.032
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.968 0.032
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.969 0.031
I74.8 Embolism and thrombosis of other arteries
0.000 0.969 0.031
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.969 0.031
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.969 0.031
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.971 0.029
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.971 0.029
I78.9 Disease of capillaries, unspecified
0.000 0.972 0.028
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.972 0.028
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.972 0.028
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.972 0.027
E85.9 Amyloidosis, unspecified
0.000 0.972 0.027
I78.8 Other diseases of capillaries
0.000 0.972 0.027
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.972 0.027
I72.0 Aneurysm of carotid artery
0.000 0.973 0.027
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.973 0.027
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.974 0.026
I02 Rheumatic chorea
0.000 0.974 0.025
I01 Rheumatic fever with heart involvement
0.000 0.974 0.025
I00 Rheumatic fever without mention of heart involvement
0.000 0.974 0.025
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.975 0.025
E80.5 Crigler-Najjar syndrome
0.000 0.975 0.025
E80.3 Defects of catalase and peroxydase
0.000 0.975 0.025
E80.2 Other porphyria
0.000 0.975 0.025
E80.1 Porphyria cutanea tarda
0.000 0.975 0.025
E80.0 Hereditary erythropoietic porphyria
0.000 0.975 0.025
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.975 0.025
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.975 0.025
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.975 0.025
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.975 0.025
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.975 0.025
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.975 0.025
E83.3 Disorders of phosphorus metabolism
0.000 0.975 0.024
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.976 0.024
I97.1 Other functional disturbances following cardiac surgery
0.000 0.977 0.023
E80.6 Other disorders of bilirubin metabolism
0.000 0.978 0.022
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.978 0.022
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.979 0.021
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.979 0.021
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.979 0.021
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.979 0.021
E89.5 Postprocedural testicular hypofunction
0.000 0.979 0.021
E89.4 Postprocedural ovarian failure
0.000 0.979 0.021
E89.1 Postprocedural hypoinsulinaemia
0.000 0.979 0.021
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.979 0.020
E89.2 Postprocedural hypoparathyroidism
0.000 0.980 0.020
E89.3 Postprocedural hypopituitarism
0.000 0.980 0.020
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.981 0.019
I97.0 Postcardiotomy syndrome
0.000 0.981 0.019
I05-I09 Chronic rheumatic heart diseases
0.000 0.981 0.019
I73 Other peripheral vascular diseases
0.000 0.981 0.019
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.981 0.018
I01.8 Other acute rheumatic heart disease
0.000 0.981 0.018
I01.2 Acute rheumatic myocarditis
0.000 0.981 0.018
I01.1 Acute rheumatic endocarditis
0.000 0.981 0.018
I01.0 Acute rheumatic pericarditis
0.000 0.981 0.018
I02.9 Rheumatic chorea without heart involvement
0.000 0.981 0.018
I02.0 Rheumatic chorea with heart involvement
0.000 0.981 0.018
I99 Other and unspecified disorders of circulatory system
0.000 0.982 0.018
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.982 0.018
E80.4 Gilbert's syndrome
0.000 0.983 0.017
I78.1 Naevus, nonneoplastic
0.000 0.983 0.017
I28 Other diseases of pulmonary vessels
0.001 0.985 0.014
I06 Rheumatic aortic valve diseases
0.000 0.986 0.014
I73.8 Other specified peripheral vascular diseases
0.000 0.986 0.014
N39.4 Other specified urinary incontinence
0.000 0.986 0.014
I09 Other rheumatic heart diseases
0.000 0.986 0.013
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.987 0.013
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.987 0.013
I98.0 Cardiovascular syphilis
0.000 0.987 0.013
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.987 0.013
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.987 0.013
I73.9 Peripheral vascular disease, unspecified
0.000 0.988 0.012
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.988 0.012
I08 Multiple valve diseases
0.000 0.988 0.012
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.988 0.012
I26 Pulmonary embolism
0.003 0.988 0.008
R16.1 Splenomegaly, not elsewhere classified
0.011 0.989 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.989 0.010
I28.1 Aneurysm of pulmonary artery
0.001 0.989 0.010
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.989 0.010
I27 Other pulmonary heart diseases
0.000 0.989 0.010
I28.8 Other specified diseases of pulmonary vessels
0.001 0.989 0.010
I07 Rheumatic tricuspid valve diseases
0.000 0.989 0.010
H04.2 Epiphora
0.000 0.989 0.011
I05 Rheumatic mitral valve diseases
0.000 0.990 0.010
I08.8 Other multiple valve diseases
0.000 0.990 0.010
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.990 0.010
I06.8 Other rheumatic aortic valve diseases
0.000 0.990 0.010
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.990 0.010
I06.1 Rheumatic aortic insufficiency
0.000 0.990 0.010
I06.0 Rheumatic aortic stenosis
0.000 0.990 0.010
I09.8 Other specified rheumatic heart diseases
0.000 0.990 0.010
I09.2 Chronic rheumatic pericarditis
0.000 0.990 0.010
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.990 0.010
I09.0 Rheumatic myocarditis
0.000 0.990 0.010
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.990 0.010
H04 Disorders of lachrymal system
0.000 0.990 0.010
I09.9 Rheumatic heart disease, unspecified
0.000 0.990 0.009
I10-I15 Hypertensive diseases
0.000 0.991 0.009
C67 Malignant neoplasm of bladder
0.009 0.991 0.000
K08.3 Retained dental root
0.000 0.991 0.009
I08.9 Multiple valve disease, unspecified
0.000 0.991 0.009
C67.1 Dome of bladder
0.009 0.991 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.991 0.009
E83.5 Disorders of calcium metabolism
0.000 0.991 0.009
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.002 0.991 0.006
I27.8 Other specified pulmonary heart diseases
0.000 0.992 0.008
C67.9 Bladder, unspecified
0.008 0.992 0.000
C67.4 Posterior wall of bladder
0.008 0.992 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.992 0.008
C67.2 Lateral wall of bladder
0.008 0.992 0.000
I08.0 Disorders of both mitral and aortic valves
0.000 0.992 0.008
C67.6 Ureteric orifice
0.008 0.992 0.000
I27.1 Kyphoscoliotic heart disease
0.000 0.992 0.008
H04.8 Other disorders of lachrymal system
0.000 0.992 0.008
I05.1 Rheumatic mitral insufficiency
0.000 0.992 0.008
I07.9 Tricuspid valve disease, unspecified
0.000 0.992 0.008
I07.8 Other tricuspid valve diseases
0.000 0.992 0.008
I07.2 Tricuspid stenosis with insufficiency
0.000 0.992 0.008
I07.0 Tricuspid stenosis
0.000 0.992 0.008
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.992 0.008
I05.2 Mitral stenosis with insufficiency
0.000 0.992 0.008
I05.8 Other mitral valve diseases
0.000 0.992 0.008
H04.9 Disorder of lachrymal system, unspecified
0.000 0.993 0.007
C67.0 Trigone of bladder
0.007 0.993 0.000
H04.6 Other changes in lachrymal passages
0.000 0.993 0.007
H04.0 Dacryoadenitis
0.000 0.993 0.007
C67.8 Overlapping lesion of bladder
0.007 0.993 0.000
I11 Hypertensive heart disease
0.000 0.993 0.007
E89.0 Postprocedural hypothyroidism
0.000 0.993 0.007
H04.4 Chronic inflammation of lachrymal passages
0.000 0.993 0.007
I27.9 Pulmonary heart disease, unspecified
0.000 0.993 0.007
K08.8 Other specified disorders of teeth and supporting structures
0.000 0.993 0.007
C67.3 Anterior wall of bladder
0.007 0.993 0.000
I13 Hypertensive heart and renal disease
0.000 0.993 0.007
C67.7 Urachus
0.007 0.993 0.000
K08 Other disorders of teeth and supporting structures
0.000 0.993 0.007
I27.0 Primary pulmonary hypertension
0.000 0.993 0.007
C67.5 Bladder neck
0.007 0.993 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.007 0.993 0.000
H04.1 Other disorders of lachrymal gland
0.000 0.994 0.006
I27.2 Other secondary pulmonary hypertension
0.000 0.994 0.006
I51.9 Heart disease, unspecified
0.000 0.994 0.006
I05.9 Mitral valve disease, unspecified
0.000 0.994 0.006
I05.0 Mitral stenosis
0.000 0.994 0.006
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.994 0.006
I15 Secondary hypertension
0.000 0.994 0.006
E61.1 Iron deficiency
0.000 0.994 0.006
K08.2 Atrophy of edentulous alveolar ridge
0.000 0.995 0.005
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.995 0.005
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.995 0.005
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.995 0.005
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.995 0.005
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.000 0.995 0.005
K08.0 Exfoliation of teeth due to systemic causes
0.000 0.995 0.005
K08.9 Disorder of teeth and supporting structures, unspecified
0.000 0.995 0.005
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.995 0.005
E28.3 Primary ovarian failure
0.005 0.995 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.995 0.004
E61 Deficiency of other nutrient elements
0.000 0.995 0.005
I15.8 Other secondary hypertension
0.000 0.995 0.004
I15.2 Hypertension secondary to endocrine disorders
0.000 0.995 0.004
I15.0 Renovascular hypertension
0.000 0.995 0.004
I51 Complications and ill-defined descriptions of heart disease
0.000 0.995 0.005
E28 Ovarian dysfunction
0.004 0.996 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.004 0.996 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.996 0.004
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.996 0.004
I07.1 Tricuspid insufficiency
0.000 0.996 0.004
I51.6 Cardiovascular disease, unspecified
0.000 0.996 0.004
L30.9 Dermatitis, unspecified
0.004 0.996 0.000
O14.9 Preeclampsia, unspecified
0.004 0.996 0.000
E23.2 Diabetes insipidus
0.004 0.996 0.000
N36.8 Other specified disorders of urethra
0.004 0.996 0.000
E23 Hypofunction and other disorders of pituitary gland
0.004 0.996 0.000
E28.2 Polycystic ovarian syndrome
0.004 0.996 0.000
E23.7 Disorder of pituitary gland, unspecified
0.004 0.996 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.996 0.004
E50-E64 Other nutritional deficiencies
0.000 0.996 0.004
E20-E35 Disorders of other endocrine glands
0.004 0.996 0.000
I73.0 Raynaud's syndrome
0.000 0.996 0.004
I51.0 Cardiac septal defect, acquired
0.000 0.996 0.004
H52.1 Myopia
0.004 0.996 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.996 0.004
E40-E46 Malnutrition
0.000 0.996 0.004
E34 Other endocrine disorders
0.004 0.996 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.996 0.003
E61.8 Deficiency of other specified nutrient elements
0.000 0.996 0.003
E61.7 Deficiency of multiple nutrient elements
0.000 0.996 0.003
E61.6 Vanadium deficiency
0.000 0.996 0.003
E61.5 Molybdenum deficiency
0.000 0.996 0.003
E61.4 Chromium deficiency
0.000 0.996 0.003
E61.3 Manganese deficiency
0.000 0.996 0.003
E61.2 Magnesium deficiency
0.000 0.996 0.003
E61.0 Copper deficiency
0.000 0.996 0.003
N36.2 Urethral caruncle
0.004 0.996 0.000
I51.5 Myocardial degeneration
0.000 0.996 0.003
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.996 0.003
E34.0 Carcinoid syndrome
0.003 0.996 0.000
E28.9 Ovarian dysfunction, unspecified
0.003 0.997 0.000
E28.8 Other ovarian dysfunction
0.003 0.997 0.000
E28.1 Androgen excess
0.003 0.997 0.000
E28.0 Oestrogen excess
0.003 0.997 0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.003 0.997 0.000
I51.7 Cardiomegaly
0.000 0.997 0.003
I51.4 Myocarditis, unspecified
0.000 0.997 0.003
I15.9 Seconday hypertension, unspecified
0.001 0.997 0.003
W19.4 Street and highway
0.003 0.997 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.997 0.003
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.997 0.003
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.997 0.003
H02.0 Entropion and trichiasis of eyelid
0.003 0.997 0.000
E23.6 Other disorders of pituitary gland
0.003 0.997 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.003 0.997 0.000
E23.1 Drug-induced hypopituitarism
0.003 0.997 0.000
E29 Testicular dysfunction
0.003 0.997 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.997 0.003
E11 Non-insulin-dependent diabetes mellitus
0.000 0.997 0.003
I12 Hypertensive renal disease
0.000 0.997 0.003
E11.2 With renal complications
0.000 0.997 0.003
E34.9 Endocrine disorder, unspecified
0.003 0.997 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.003 0.997 0.000
E27 Other disorders of adrenal gland
0.003 0.997 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.997 0.003
E63 Other nutritional deficiencies
0.000 0.997 0.003
E56 Other vitamin deficiencies
0.000 0.997 0.003
E51 Thiamine deficiency
0.000 0.997 0.003
E50 Vitamin A deficiency
0.000 0.997 0.003
E60 Dietary zinc deficiency
0.000 0.997 0.003
E59 Dietary selenium deficiency
0.000 0.997 0.003
E58 Dietary calcium deficiency
0.000 0.997 0.003
E54 Ascorbic acid deficiency
0.000 0.997 0.003
E52 Niacin deficiency [pellagra]
0.000 0.997 0.003
E35 Disorders of endocrine glands in diseases classified elsewhere
0.003 0.997 0.000
E32 Diseases of thymus
0.003 0.997 0.000
E31 Polyglandular dysfunction
0.003 0.997 0.000
E30 Disorders of puberty, not elsewhere classified
0.003 0.997 0.000
E25 Adrenogenital disorders
0.003 0.997 0.000
N36 Other disorders of urethra
0.003 0.997 0.000
E11.0 With coma
0.000 0.997 0.003
E23.0 Hypopituitarism
0.003 0.997 0.000
E22 Hyperfunction of pituitary gland
0.003 0.997 0.000
E24 Cushing's syndrome
0.003 0.997 0.000
E20 Hypoparathyroidism
0.003 0.997 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.997 0.003
E26 Hyperaldosteronism
0.003 0.997 0.000
E27.8 Other specified disorders of adrenal gland
0.003 0.997 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.997 0.003
E45 Retarded development following protein-energy malnutrition
0.000 0.997 0.003
E43 Unspecified severe protein-energy malnutrition
0.000 0.997 0.003
E42 Marasmic kwashiorkor
0.000 0.997 0.003
E41 Nutritional marasmus
0.000 0.997 0.003
E40 Kwashiorkor
0.000 0.997 0.003
E11.1 With ketoacidosis
0.000 0.997 0.003
E34.5 Androgen resistance syndrome
0.003 0.997 0.000
E34.4 Constitutional tall stature
0.003 0.997 0.000
E34.3 Short stature, not elsewhere classified
0.003 0.997 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.003 0.997 0.000
E34.1 Other hypersecretion of intestinal hormones
0.003 0.997 0.000
S82.10 Fracture of upper end of tibia (closed)
0.003 0.997 0.000
E34.8 Other specified endocrine disorders
0.003 0.997 0.000
T17.2 Foreign body in pharynx
0.003 0.997 0.000
E87.3 Alkalosis
0.000 0.997 0.003
E11.5 With peripheral circulatory complications
0.000 0.997 0.003
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.000 0.997 0.003
E15 Nondiabetic hypoglycaemic coma
0.000 0.997 0.003
E87.5 Hyperkalaemia
0.000 0.997 0.003
E16 Other disorders of pancreatic internal secretion
0.000 0.997 0.003
E10-E14 Diabetes mellitus
0.000 0.997 0.003
E29.1 Testicular hypofunction
0.003 0.997 0.000
K62.0 Anal polyp
0.003 0.997 0.000
E22.1 Hyperprolactinaemia
0.002 0.997 0.000
E29.9 Testicular dysfunction, unspecified
0.002 0.997 0.000
E29.8 Other testicular dysfunction
0.002 0.997 0.000
E29.0 Testicular hyperfunction
0.002 0.997 0.000
N36.9 Urethral disorder, unspecified
0.002 0.997 0.000
E11.7 With multiple complications
0.000 0.997 0.002
E22.0 Acromegaly and pituitary gigantism
0.002 0.997 0.000
E27.9 Disorder of adrenal gland, unspecified
0.002 0.997 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.997 0.003
H52.2 Astigmatism
0.002 0.997 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.002 0.997 0.000
I30-I52 Other forms of heart disease
0.000 0.997 0.003
E27.5 Adrenomedullary hyperfunction
0.002 0.997 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.002 0.997 0.000
E27.0 Other adrenocortical overactivity
0.002 0.997 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.997 0.002
E50.8 Other manifestations of vitamin A deficiency
0.000 0.997 0.002
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.997 0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.997 0.002
E50.5 Vitamin A deficiency with night blindness
0.000 0.997 0.002
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.997 0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.997 0.002
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.997 0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.997 0.002
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.997 0.002
E51.9 Thiamine deficiency, unspecified
0.000 0.997 0.002
E51.8 Other manifestations of thiamine deficiency
0.000 0.997 0.002
E51.2 Wernicke's encephalopathy
0.000 0.997 0.002
E51.1 Beriberi
0.000 0.997 0.002
E56.9 Vitamin deficiency, unspecified
0.000 0.997 0.002
E56.8 Deficiency of other vitamins
0.000 0.997 0.002
E56.1 Deficiency of vitamin K
0.000 0.997 0.002
E56.0 Deficiency of vitamin E
0.000 0.997 0.002
E63.9 Nutritional deficiency, unspecified
0.000 0.997 0.002
E63.8 Other specified nutritional deficiencies
0.000 0.997 0.002
E63.1 Imbalance of constituents of food intake
0.000 0.997 0.002
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.997 0.002
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.997 0.002
E64.8 Sequelae of other nutritional deficiencies
0.000 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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