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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs186868868
log Bayes Factor = 23.5439
Chromosome 8   position 19,863,803  (GRCh37) Explore rs186868868 on Ensembl!
Variant rs186868868 is part of Cluster X0156

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
K55-K64 Other diseases of intestines
0.997 0.003 0.000
E70-E90 Metabolic disorders
0.996 0.004 0.000
B95-B98 Bacterial, viral and other infectious agents
0.994 0.006 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.989 0.011 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.987 0.013 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.987 0.013 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.985 0.015 0.000
G40-G47 Episodic and paroxysmal disorders
0.985 0.015 0.000
I71 Aortic aneurysm and dissection
0.984 0.016 0.000
I73 Other peripheral vascular diseases
0.983 0.017 0.000
E78.0 Pure hypercholesterolaemia
0.982 0.018 0.000
K50-K52 Noninfective enteritis and colitis
0.981 0.019 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.981 0.019 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.979 0.021 0.000
N72 Inflammatory disease of cervix uteri
0.978 0.022 0.000
A30-A49 Other bacterial diseases
0.975 0.025 0.000
K57 Diverticular disease of intestine
0.975 0.025 0.000
I73.9 Peripheral vascular disease, unspecified
0.975 0.025 0.000
I60-I69 Cerebrovascular diseases
0.972 0.028 0.000
R42 Dizziness and giddiness
0.972 0.028 0.000
M70-M79 Other soft tissue disorders
0.969 0.031 0.000
Chapter VIII Diseases of the ear and mastoid process
0.967 0.033 0.000
K62 Other diseases of anus and rectum
0.966 0.034 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.966 0.034 0.000
K51 Ulcerative colitis
0.963 0.037 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.962 0.038 0.000
H30-H36 Disorders of choroid and retina
0.961 0.039 0.000
M50-M54 Other dorsopathies
0.947 0.053 0.000
K51.9 Ulcerative colitis, unspecified
0.946 0.054 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.946 0.054 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.945 0.055 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.943 0.057 0.000
R07 Pain in throat and chest
0.941 0.059 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.940 0.060 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.938 0.062 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.934 0.066 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.931 0.069 0.000
R07.3 Other chest pain
0.929 0.071 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.927 0.073 0.000
Chapter XXI Factors influencing health status and contact with health services
0.926 0.074 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.925 0.075 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.920 0.080 0.000
H35 Other retinal disorders
0.920 0.080 0.000
H65-H75 Diseases of middle ear and mastoid
0.919 0.081 0.000
A41 Other septicaemia
0.914 0.086 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.913 0.087 0.000
A00-A09 Intestinal infectious diseases
0.913 0.087 0.000
I95 Hypotension
0.913 0.087 0.000
M54 Dorsalgia
0.913 0.087 0.000
K62.0 Anal polyp
0.912 0.088 0.000
K90-K93 Other diseases of the digestive system
0.909 0.091 0.000
K55 Vascular disorders of intestine
0.905 0.095 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.901 0.099 0.000
G47 Sleep disorders
0.897 0.103 0.000
M80-M85 Disorders of bone density and structure
0.894 0.106 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.891 0.109 0.000
I65.2 Occlusion and stenosis of carotid artery
0.890 0.110 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.883 0.117 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.882 0.118 0.000
L08 Other local infections of skin and subcutaneous tissue
0.879 0.121 0.000
Chapter XX External causes of morbidity and mortality
0.878 0.122 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.877 0.123 0.000
M79.8 Other specified soft tissue disorders
0.872 0.128 0.000
I60 Subarachnoid haemorrhage
0.871 0.129 0.000
I77 Other disorders of arteries and arterioles
0.870 0.130 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.870 0.130 0.000
I30-I52 Other forms of heart disease
0.868 0.132 0.000
R02 Gangrene, not elsewhere classified
0.864 0.136 0.000
H35.3 Degeneration of macula and posterior pole
0.862 0.138 0.000
K62.8 Other specified diseases of anus and rectum
0.860 0.140 0.000
L20-L30 Dermatitis and eczema
0.859 0.141 0.000
G43 Migraine
0.855 0.145 0.000
A49 Bacterial infection of unspecified site
0.855 0.145 0.000
K62.6 Ulcer of anus and rectum
0.854 0.146 0.000
H25-H28 Disorders of lens
0.853 0.147 0.000
E20-E35 Disorders of other endocrine glands
0.851 0.149 0.000
N17-N19 Renal failure
0.848 0.152 0.000
I95.9 Hypotension, unspecified
0.847 0.153 0.000
I10-I15 Hypertensive diseases
0.845 0.155 0.000
R05 Cough
0.844 0.156 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.843 0.157 0.000
N87 Dysplasia of cervix uteri
0.842 0.158 0.000
M75 Shoulder lesions
0.842 0.158 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.841 0.159 0.000
H55-H59 Other disorders of eye and adnexa
0.839 0.161 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.838 0.162 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.838 0.162 0.000
Chapter XXII Codes for special purposes
0.838 0.162 0.000
N76 Other inflammation of vagina and vulva
0.837 0.163 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.837 0.163 0.000
Z49 Care involving dialysis
0.836 0.164 0.000
H80-H83 Diseases of inner ear
0.836 0.164 0.000
I51 Complications and ill-defined descriptions of heart disease
0.833 0.167 0.000
M54.5 Low back pain
0.833 0.167 0.000
E10 Insulin-dependent diabetes mellitus
0.832 0.168 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.831 0.169 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.831 0.169 0.000
E11.3 With ophthalmic complications
0.829 0.171 0.000
H71 Cholesteatoma of middle ear
0.829 0.171 0.000
I95.1 Orthostatic hypotension
0.828 0.172 0.000
A04 Other bacterial intestinal infections
0.828 0.172 0.000
E11.5 With peripheral circulatory complications
0.826 0.174 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.826 0.174 0.000
L03 Cellulitis
0.825 0.175 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.825 0.175 0.000
G40 Epilepsy
0.825 0.175 0.000
K55.2 Angiodysplasia of colon
0.824 0.176 0.000
H73 Other disorders of tympanic membrane
0.822 0.178 0.000
I78 Diseases of capillaries
0.820 0.180 0.000
H34 Retinal vascular occlusions
0.820 0.180 0.000
L60-L75 Disorders of skin appendages
0.819 0.181 0.000
G30-G32 Other degenerative diseases of the nervous system
0.819 0.181 0.000
G90-G99 Other disorders of the nervous system
0.817 0.183 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.817 0.183 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.817 0.183 0.000
N85.4 Malposition of uterus
0.816 0.184 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.816 0.184 0.000
M79.0 Rheumatism, unspecified
0.815 0.185 0.000
I05-I09 Chronic rheumatic heart diseases
0.814 0.186 0.000
H40-H42 Glaucoma
0.814 0.186 0.000
I74 Arterial embolism and thrombosis
0.813 0.187 0.000
L05 Pilonidal cyst
0.813 0.187 0.000
B35-B49 Mycoses
0.813 0.187 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.811 0.188 0.000
N95 Menopausal and other perimenopausal disorders
0.811 0.189 0.000
I71.0 Dissection of aorta [any part]
0.808 0.192 0.000
I62 Other nontraumatic intracranial haemorrhage
0.808 0.192 0.000
K92 Other diseases of digestive system
0.807 0.193 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.806 0.194 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.805 0.194 0.000
M40-M43 Deforming dorsopathies
0.802 0.198 0.000
N93 Other abnormal uterine and vaginal bleeding
0.801 0.199 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.801 0.199 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.800 0.200 0.000
N85.0 Endometrial glandular hyperplasia
0.798 0.202 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.795 0.205 0.000
H25 Senile cataract
0.794 0.206 0.000
A40 Streptococcal septicaemia
0.794 0.206 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.793 0.207 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.793 0.207 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.792 0.208 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.792 0.208 0.000
K56.2 Volvulus
0.791 0.209 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.791 0.209 0.000
Z49.1 Extracorporeal dialysis
0.791 0.209 0.000
G47.3 Sleep apnoea
0.790 0.210 0.000
E78.2 Mixed hyperlipidaemia
0.790 0.210 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.789 0.211 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.786 0.214 0.000
B99-B99 Other infectious diseases
0.785 0.214 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.785 0.215 0.000
S00-S09 Injuries to the head
0.783 0.217 0.000
E83 Disorders of mineral metabolism
0.783 0.217 0.000
N18 Chronic renal failure
0.782 0.218 0.000
E14 Unspecified diabetes mellitus
0.782 0.218 0.000
I50 Heart failure
0.781 0.219 0.000
M75.0 Adhesive capsulitis of shoulder
0.781 0.219 0.000
Z53.9 Procedure not carried out, unspecified reason
0.780 0.220 0.000
N73 Other female pelvic inflammatory diseases
0.778 0.222 0.000
A41.9 Septicaemia, unspecified
0.777 0.223 0.000
A41.8 Other specified septicaemia
0.776 0.224 0.000
I12 Hypertensive renal disease
0.775 0.225 0.000
I72 Other aneurysm
0.775 0.225 0.000
E86 Volume depletion
0.774 0.226 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.773 0.227 0.000
K62.1 Rectal polyp
0.773 0.227 0.000
K62.4 Stenosis of anus and rectum
0.771 0.229 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.771 0.229 0.000
H43-H45 Disorders of vitreous body and globe
0.770 0.230 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.768 0.232 0.000
L03.1 Cellulitis of other parts of limb
0.767 0.233 0.000
K52 Other non-infective gastro-enteritis and colitis
0.767 0.233 0.000
G43.9 Migraine, unspecified
0.767 0.233 0.000
Z53.0 Procedure not carried out because of contraindication
0.767 0.233 0.000
Z40 Prophylactic surgery
0.765 0.235 0.000
I51.8 Other ill-defined heart diseases
0.765 0.235 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.765 0.235 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.765 0.235 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.764 0.236 0.000
M91-M94 Chondropathies
0.762 0.238 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.762 0.238 0.000
N99-N99 Other disorders of the genitourinary system
0.762 0.238 0.000
I51.7 Cardiomegaly
0.762 0.238 0.000
M54.56 Low back pain (Lumbar region)
0.761 0.239 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.761 0.239 0.000
E40-E46 Malnutrition
0.761 0.239 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.760 0.240 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.759 0.241 0.000
E11.2 With renal complications
0.758 0.242 0.000
M81 Osteoporosis without pathological fracture
0.758 0.242 0.000
G70-G73 Diseases of myoneural junction and muscle
0.757 0.243 0.000
K91.4 Colostomy and enterostomy malfunction
0.756 0.244 0.000
M84 Disorders of continuity of bone
0.753 0.246 0.000
R07.1 Chest pain on breathing
0.753 0.247 0.000
H73.8 Other specified disorders of tympanic membrane
0.752 0.248 0.000
M54.9 Dorsalgia, unspecified
0.751 0.249 0.000
H10-H13 Disorders of conjunctiva
0.749 0.251 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.747 0.253 0.000
G47.9 Sleep disorder, unspecified
0.746 0.254 0.000
N71 Inflammatory disease of uterus, except cervix
0.745 0.255 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.743 0.257 0.000
E88 Other metabolic disorders
0.742 0.258 0.000
L50-L54 Urticaria and erythema
0.741 0.259 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.741 0.259 0.000
K62.7 Radiation proctitis
0.740 0.260 0.000
M72 Fibroblastic disorders
0.740 0.260 0.000
M54.2 Cervicalgia
0.740 0.260 0.000
E13 Other specified diabetes mellitus
0.740 0.260 0.000
S01 Open wound of head
0.739 0.261 0.000
H35.6 Retinal haemorrhage
0.739 0.261 0.000
M51 Other intervertebral disk disorders
0.738 0.262 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.737 0.263 0.000
H36 Retinal disorders in diseases classified elsewhere
0.736 0.264 0.000
R79 Other abnormal findings of blood chemistry
0.736 0.264 0.000
K51.4 Pseudopolyposis of colon
0.734 0.266 0.000
K50 Crohn's disease [regional enteritis]
0.733 0.267 0.000
R04 Haemorrhage from respiratory passages
0.733 0.267 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.730 0.270 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.729 0.271 0.000
H25.1 Senile nuclear cataract
0.729 0.271 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.729 0.271 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.727 0.273 0.000
N76.0 Acute vaginitis
0.727 0.273 0.000
R50-R69 General symptoms and signs
0.727 0.273 0.000
N00-N08 Glomerular diseases
0.726 0.274 0.000
L27 Dermatitis due to substances taken internally
0.725 0.275 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.725 0.275 0.000
R45 Symptoms and signs involving emotional state
0.724 0.276 0.000
N95.0 Postmenopausal bleeding
0.724 0.276 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.723 0.277 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.722 0.278 0.000
Z30 Contraceptive management
0.722 0.278 0.000
Z22 Carrier of infectious disease
0.722 0.278 0.000
N10-N16 Renal tubulo-interstitial diseases
0.722 0.278 0.000
M75.5 Bursitis of shoulder
0.720 0.280 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.719 0.281 0.000
I50.9 Heart failure, unspecified
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.6 With other specified complications
0.717 0.283 0.000
E11.1 With ketoacidosis
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
H66 Suppurative and unspecified otitis media
0.716 0.284 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.716 0.284 0.000
M77 Other enthesopathies
0.716 0.284 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.715 0.285 0.000
E85 Amyloidosis
0.714 0.286 0.000
E84 Cystic fibrosis
0.714 0.286 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
E73 Lactose intolerance
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
H35.0 Background retinopathy and retinal vascular changes
0.714 0.286 0.000
T66-T78 Other and unspecified effects of external causes
0.714 0.286 0.000
Y43 Primarily systemic agents
0.714 0.286 0.000
E11.4 With neurological complications
0.713 0.287 0.000
R94 Abnormal results of function studies
0.713 0.287 0.000
M71 Other bursopathies
0.713 0.287 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.713 0.287 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.712 0.288 0.000
H53-H54 Visual disturbances and blindness
0.711 0.289 0.000
Y40 Systemic antibiotics
0.711 0.289 0.000
M53 Other dorsopathies, not elsewhere classified
0.710 0.290 0.000
H35.9 Retinal disorder, unspecified
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.710 0.290 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.709 0.291 0.000
E78.8 Other disorders of lipoprotein metabolism
0.709 0.291 0.000
E78.6 Lipoprotein deficiency
0.709 0.291 0.000
E78.4 Other hyperlipidaemia
0.709 0.291 0.000
E78.3 Hyperchylomicronaemia
0.709 0.291 0.000
E78.1 Pure hyperglyceridaemia
0.709 0.291 0.000
B25-B34 Other viral diseases
0.708 0.292 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.708 0.292 0.000
M60-M63 Disorders of muscles
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
L10-L14 Bullous disorders
0.707 0.292 0.000
N86 Erosion and ectropion of cervix uteri
0.707 0.293 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.707 0.293 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.706 0.294 0.000
M79.6 Pain in limb
0.706 0.294 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.706 0.294 0.000
G44 Other headache syndromes
0.706 0.294 0.000
G41 Status epilepticus
0.706 0.294 0.000
H90-H95 Other disorders of ear
0.706 0.294 0.000
G30 Alzheimer's disease
0.705 0.295 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.705 0.295 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.705 0.295 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.705 0.295 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.705 0.295 0.000
I73.8 Other specified peripheral vascular diseases
0.705 0.295 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.705 0.295 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.705 0.295 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.704 0.296 0.000
M54.4 Lumbago with sciatica
0.704 0.296 0.000
R46 Symptoms and signs involving appearance and behaviour
0.703 0.297 0.000
R43 Disturbances of smell and taste
0.703 0.297 0.000
K62.9 Disease of anus and rectum, unspecified
0.703 0.297 0.000
K56.6 Other and unspecified intestinal obstruction
0.703 0.297 0.000
I77.1 Stricture of artery
0.703 0.297 0.000
I12.0 Hypertensive renal disease with renal failure
0.703 0.297 0.000
Z47 Other orthopaedic follow-up care
0.702 0.298 0.000
M54.3 Sciatica
0.702 0.298 0.000
A49.1 Streptococcal infection, unspecified
0.701 0.298 0.000
K51.8 Other ulcerative colitis
0.700 0.300 0.000
H69 Other disorders of Eustachian tube
0.700 0.300 0.000
A48 Other bacterial diseases, not elsewhere classified
0.699 0.301 0.000
A44 Bartonellosis
0.699 0.301 0.000
A43 Nocardiosis
0.699 0.301 0.000
A42 Actinomycosis
0.699 0.301 0.000
A39 Meningococcal infection
0.699 0.301 0.000
A37 Whooping cough
0.699 0.301 0.000
A36 Diphtheria
0.699 0.301 0.000
A32 Listeriosis
0.699 0.301 0.000
A31 Infection due to other mycobacteria
0.699 0.301 0.000
A30 Leprosy [Hansen's disease]
0.699 0.301 0.000
A46 Erysipelas
0.699 0.301 0.000
A38 Scarlet fever
0.699 0.301 0.000
A35 Other tetanus
0.699 0.301 0.000
A34 Obstetrical tetanus
0.699 0.301 0.000
A33 Tetanus neonatorum
0.699 0.301 0.000
E78.5 Hyperlipidaemia, unspecified
0.699 0.301 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.699 0.301 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.699 0.301 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.699 0.301 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.699 0.301 0.000
H83 Other diseases of inner ear
0.698 0.302 0.000
K55.9 Vascular disorder of intestine, unspecified
0.698 0.302 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.697 0.303 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.697 0.303 0.000
H34.8 Other retinal vascular occlusions
0.696 0.304 0.000
M76 Enthesopathies of lower limb, excluding foot
0.695 0.305 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.695 0.305 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.695 0.305 0.000
L05.0 Pilonidal cyst with abscess
0.694 0.306 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.693 0.307 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.693 0.307 0.000
K62.2 Anal prolapse
0.693 0.307 0.000
L04 Acute lymphadenitis
0.693 0.307 0.000
L01 Impetigo
0.693 0.307 0.000
L00 Staphylococcal scalded skin syndrome
0.693 0.307 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.693 0.307 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.693 0.307 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.692 0.308 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.692 0.308 0.000
I78.1 Naevus, nonneoplastic
0.691 0.309 0.000
G95 Other diseases of spinal cord
0.691 0.309 0.000
Z45 Adjustment and management of implanted device
0.691 0.309 0.000
K51.5 Mucosal proctocolitis
0.690 0.310 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.690 0.310 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.690 0.310 0.000
I69 Sequelae of cerebrovascular disease
0.690 0.310 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.689 0.311 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.689 0.311 0.000
K56.7 Ileus, unspecified
0.689 0.311 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.689 0.311 0.000
K63 Other diseases of intestine
0.689 0.311 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.689 0.311 0.000
H31 Other disorders of choroid
0.689 0.311 0.000
H30 Chorioretinal inflammation
0.689 0.311 0.000
E23 Hypofunction and other disorders of pituitary gland
0.688 0.312 0.000
H35.4 Peripheral retinal degeneration
0.688 0.312 0.000
H55 Nystagmus and other irregular eye movements
0.687 0.313 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.687 0.313 0.000
I61 Intracerebral haemorrhage
0.686 0.313 0.000
A49.0 Staphylococcal infection, unspecified
0.686 0.314 0.000
R01 Cardiac murmurs and other cardiac sounds
0.686 0.314 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.686 0.314 0.000
I77.8 Other specified disorders of arteries and arterioles
0.685 0.315 0.000
S50-S59 Injuries to the elbow and forearm
0.685 0.315 0.000
Z29 Need for other prophylactic measures
0.684 0.316 0.000
H40 Glaucoma
0.682 0.318 0.000
S80-S89 Injuries to the knee and lower leg
0.682 0.318 0.000
N85.1 Endometrial adenomatous hyperplasia
0.682 0.318 0.000
N88 Other noninflammatory disorders of cervix uteri
0.681 0.319 0.000
N60-N64 Disorders of breast
0.680 0.320 0.000
N87.0 Mild cervical dysplasia
0.680 0.320 0.000
N18.0 End-stage renal disease
0.680 0.320 0.000
N89 Other noninflammatory disorders of vagina
0.680 0.320 0.000
M80 Osteoporosis with pathological fracture
0.680 0.320 0.000
E22 Hyperfunction of pituitary gland
0.679 0.321 0.000
H52 Disorders of refraction and accommodation
0.679 0.321 0.000
B37 Candidiasis
0.679 0.321 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.678 0.322 0.000
I99 Other and unspecified disorders of circulatory system
0.678 0.322 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.678 0.322 0.000
N98 Complications associated with artificial fertilisation
0.678 0.322 0.000
N91 Absent, scanty and rare menstruation
0.678 0.322 0.000
N82 Fistulae involving female genital tract
0.678 0.322 0.000
N96 Habitual aborter
0.678 0.322 0.000
L03.9 Cellulitis, unspecified
0.678 0.322 0.000
H60-H62 Diseases of external ear
0.677 0.322 0.000
I50.0 Congestive heart failure
0.677 0.323 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.676 0.324 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.676 0.324 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.676 0.324 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.676 0.324 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.676 0.324 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.675 0.325 0.000
E10.2 With renal complications
0.675 0.325 0.000
R27 Other lack of coordination
0.675 0.325 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.674 0.326 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.674 0.326 0.000
G45.3 Amaurosis fugax
0.674 0.326 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.674 0.326 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.674 0.326 0.000
G45.0 Vertebro-basilar artery syndrome
0.674 0.326 0.000
H81 Disorders of vestibular function
0.674 0.326 0.000
R53 Malaise and fatigue
0.673 0.327 0.000
L73 Other follicular disorders
0.672 0.327 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.672 0.328 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.672 0.328 0.000
Z57 Occupational exposure to risk-factors
0.672 0.328 0.000
N18.9 Chronic renal failure, unspecified
0.672 0.328 0.000
Z42 Follow-up care involving plastic surgery
0.672 0.328 0.000
I70 Atherosclerosis
0.671 0.329 0.000
A04.8 Other specified bacterial intestinal infections
0.671 0.329 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.670 0.330 0.000
M86-M90 Other osteopathies
0.669 0.331 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.669 0.331 0.000
Y57 Other and unspecified drugs and medicaments
0.669 0.331 0.000
K56.4 Other impaction of intestine
0.668 0.332 0.000
A04.5 Campylobacter enteritis
0.668 0.332 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.668 0.332 0.000
M79.9 Soft tissue disorder, unspecified
0.668 0.332 0.000
M79.5 Residual foreign body in soft tissue
0.668 0.332 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.668 0.332 0.000
M79.3 Panniculitis, unspecified
0.668 0.332 0.000
M79.2 Neuralgia and neuritis, unspecified
0.668 0.332 0.000
M79.1 Myalgia
0.668 0.332 0.000
V20-V29 Motorcycle rider injured in transport accident
0.667 0.333 0.000
E50-E64 Other nutritional deficiencies
0.665 0.335 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.665 0.335 0.000
A40.0 Septicaemia due to streptococcus, group A
0.664 0.336 0.000
R47-R49 Symptoms and signs involving speech and voice
0.664 0.336 0.000
I07 Rheumatic tricuspid valve diseases
0.664 0.336 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.663 0.337 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.663 0.337 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.663 0.337 0.000
I65.1 Occlusion and stenosis of basilar artery
0.663 0.337 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.663 0.337 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.661 0.339 0.000
I33 Acute and subacute endocarditis
0.661 0.339 0.000
I77.6 Arteritis, unspecified
0.661 0.339 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.660 0.340 0.000
R80 Isolated proteinuria
0.660 0.340 0.000
A49.8 Other bacterial infections of unspecified site
0.660 0.340 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.660 0.340 0.000
M81.9 Osteoporosis, unspecified
0.660 0.340 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.660 0.340 0.000
N85.7 Haematometra
0.660 0.340 0.000
N85.6 Intra-uterine synechiae
0.660 0.340 0.000
N85.5 Inversion of uterus
0.660 0.340 0.000
N85.3 Subinvolution of uterus
0.660 0.340 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.659 0.341 0.000
H35.7 Separation of retinal layers
0.659 0.341 0.000
H35.5 Hereditary retinal dystrophy
0.659 0.341 0.000
H35.2 Other proliferative retinopathy
0.659 0.341 0.000
H35.1 Retinopathy of prematurity
0.659 0.341 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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