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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1441759
log Bayes Factor = 22.8185
Chromosome 8   position 19,865,563  (GRCh37) Explore rs1441759 on Ensembl!
Variant rs1441759 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
E11.9 Without complications
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.993 0.007 0.000
Chapter XI Diseases of the digestive system
0.991 0.009 0.000
E78.0 Pure hypercholesterolaemia
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
M50-M54 Other dorsopathies
0.988 0.012 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.987 0.013 0.000
K55-K64 Other diseases of intestines
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.986 0.014 0.000
B95-B98 Bacterial, viral and other infectious agents
0.985 0.015 0.000
I60-I69 Cerebrovascular diseases
0.984 0.016 0.000
I73 Other peripheral vascular diseases
0.983 0.017 0.000
H30-H36 Disorders of choroid and retina
0.983 0.017 0.000
M70-M79 Other soft tissue disorders
0.983 0.017 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.981 0.019 0.000
Chapter VI Diseases of the nervous system
0.979 0.021 0.000
M54 Dorsalgia
0.978 0.022 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.975 0.025 0.000
I73.9 Peripheral vascular disease, unspecified
0.973 0.027 0.000
R42 Dizziness and giddiness
0.973 0.027 0.000
K50-K52 Noninfective enteritis and colitis
0.971 0.029 0.000
I51 Complications and ill-defined descriptions of heart disease
0.971 0.029 0.000
G40-G47 Episodic and paroxysmal disorders
0.970 0.030 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.970 0.030 0.000
Chapter VIII Diseases of the ear and mastoid process
0.967 0.033 0.000
I71 Aortic aneurysm and dissection
0.963 0.037 0.000
K51 Ulcerative colitis
0.958 0.042 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.957 0.043 0.000
H35 Other retinal disorders
0.954 0.046 0.000
A30-A49 Other bacterial diseases
0.945 0.055 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.943 0.057 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.942 0.058 0.000
I51.7 Cardiomegaly
0.941 0.059 0.000
K62 Other diseases of anus and rectum
0.941 0.059 0.000
K57 Diverticular disease of intestine
0.940 0.060 0.000
K51.9 Ulcerative colitis, unspecified
0.939 0.061 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.938 0.062 0.000
M54.5 Low back pain
0.937 0.063 0.000
Z49 Care involving dialysis
0.936 0.064 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.935 0.065 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.935 0.065 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.930 0.070 0.000
I50 Heart failure
0.926 0.074 0.000
Chapter XIV Diseases of the genitourinary system
0.925 0.075 0.000
H65-H75 Diseases of middle ear and mastoid
0.922 0.078 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.922 0.078 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.921 0.079 0.000
I10-I15 Hypertensive diseases
0.918 0.082 0.000
N72 Inflammatory disease of cervix uteri
0.916 0.084 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.915 0.085 0.000
G47 Sleep disorders
0.910 0.090 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.904 0.096 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.901 0.099 0.000
I65.2 Occlusion and stenosis of carotid artery
0.900 0.100 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.899 0.101 0.000
M79.8 Other specified soft tissue disorders
0.896 0.104 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.895 0.105 0.000
K55 Vascular disorders of intestine
0.893 0.107 0.000
Z49.1 Extracorporeal dialysis
0.893 0.107 0.000
R07 Pain in throat and chest
0.892 0.108 0.000
I51.8 Other ill-defined heart diseases
0.891 0.109 0.000
H35.3 Degeneration of macula and posterior pole
0.889 0.111 0.000
S00-S09 Injuries to the head
0.886 0.114 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.885 0.115 0.000
I12 Hypertensive renal disease
0.885 0.115 0.000
Z53.9 Procedure not carried out, unspecified reason
0.881 0.119 0.000
R79 Other abnormal findings of blood chemistry
0.877 0.123 0.000
K62.0 Anal polyp
0.876 0.124 0.000
K62.8 Other specified diseases of anus and rectum
0.876 0.124 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.872 0.128 0.000
R07.3 Other chest pain
0.871 0.129 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.871 0.129 0.000
R02 Gangrene, not elsewhere classified
0.870 0.130 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.870 0.130 0.000
M80-M85 Disorders of bone density and structure
0.870 0.130 0.000
E10 Insulin-dependent diabetes mellitus
0.869 0.131 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.869 0.131 0.000
Z40 Prophylactic surgery
0.868 0.132 0.000
E11.5 With peripheral circulatory complications
0.867 0.133 0.000
S01 Open wound of head
0.867 0.133 0.000
I60 Subarachnoid haemorrhage
0.866 0.134 0.000
L20-L30 Dermatitis and eczema
0.865 0.135 0.000
M54.2 Cervicalgia
0.859 0.141 0.000
K62.6 Ulcer of anus and rectum
0.859 0.141 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.857 0.143 0.000
R05 Cough
0.857 0.143 0.000
A00-A09 Intestinal infectious diseases
0.857 0.143 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.856 0.144 0.000
H25-H28 Disorders of lens
0.856 0.144 0.000
I77 Other disorders of arteries and arterioles
0.852 0.148 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.850 0.150 0.000
I50.9 Heart failure, unspecified
0.849 0.151 0.000
E20-E35 Disorders of other endocrine glands
0.848 0.152 0.000
I12.0 Hypertensive renal disease with renal failure
0.847 0.153 0.000
M79.0 Rheumatism, unspecified
0.846 0.154 0.000
E11.3 With ophthalmic complications
0.846 0.154 0.000
H80-H83 Diseases of inner ear
0.846 0.154 0.000
M54.9 Dorsalgia, unspecified
0.843 0.157 0.000
H55-H59 Other disorders of eye and adnexa
0.839 0.161 0.000
M51 Other intervertebral disk disorders
0.839 0.161 0.000
Chapter XXII Codes for special purposes
0.837 0.163 0.000
H73 Other disorders of tympanic membrane
0.836 0.164 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.835 0.165 0.000
Z30 Contraceptive management
0.834 0.166 0.000
A41 Other septicaemia
0.833 0.167 0.000
H71 Cholesteatoma of middle ear
0.830 0.170 0.000
H40-H42 Glaucoma
0.829 0.171 0.000
I50.0 Congestive heart failure
0.829 0.171 0.000
I74 Arterial embolism and thrombosis
0.828 0.172 0.000
S01.8 Open wound of other parts of head
0.828 0.172 0.000
G47.3 Sleep apnoea
0.828 0.172 0.000
L08 Other local infections of skin and subcutaneous tissue
0.827 0.173 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.824 0.176 0.000
M75 Shoulder lesions
0.824 0.176 0.000
G30-G32 Other degenerative diseases of the nervous system
0.822 0.177 0.000
M54.56 Low back pain (Lumbar region)
0.822 0.178 0.000
Z47 Other orthopaedic follow-up care
0.821 0.179 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.820 0.180 0.000
H34 Retinal vascular occlusions
0.819 0.181 0.000
E78.2 Mixed hyperlipidaemia
0.817 0.183 0.000
I62 Other nontraumatic intracranial haemorrhage
0.817 0.183 0.000
K55.2 Angiodysplasia of colon
0.812 0.188 0.000
I05-I09 Chronic rheumatic heart diseases
0.810 0.189 0.000
E14 Unspecified diabetes mellitus
0.809 0.191 0.000
G43 Migraine
0.807 0.193 0.000
N76 Other inflammation of vagina and vulva
0.805 0.194 0.000
A49 Bacterial infection of unspecified site
0.805 0.195 0.000
L03 Cellulitis
0.804 0.196 0.000
H25 Senile cataract
0.802 0.198 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.800 0.200 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.799 0.201 0.000
L05 Pilonidal cyst
0.798 0.202 0.000
B35-B49 Mycoses
0.797 0.203 0.000
M79.6 Pain in limb
0.795 0.205 0.000
I95 Hypotension
0.793 0.207 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.792 0.208 0.000
M40-M43 Deforming dorsopathies
0.791 0.209 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.789 0.211 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.787 0.213 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.787 0.213 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.786 0.214 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.785 0.215 0.000
H36 Retinal disorders in diseases classified elsewhere
0.785 0.215 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.784 0.216 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.783 0.217 0.000
L60-L75 Disorders of skin appendages
0.783 0.217 0.000
K56.2 Volvulus
0.778 0.222 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.777 0.223 0.000
I78 Diseases of capillaries
0.776 0.224 0.000
Z45 Adjustment and management of implanted device
0.775 0.225 0.000
H73.8 Other specified disorders of tympanic membrane
0.775 0.225 0.000
M54.22 Cervicalgia (Cervical region)
0.774 0.226 0.000
M54.59 Low back pain (Site unspecified)
0.773 0.227 0.000
I35 Nonrheumatic aortic valve disorders
0.772 0.228 0.000
G47.9 Sleep disorder, unspecified
0.772 0.228 0.000
Z57 Occupational exposure to risk-factors
0.772 0.228 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.772 0.228 0.000
Z53.0 Procedure not carried out because of contraindication
0.770 0.230 0.000
A40 Streptococcal septicaemia
0.769 0.231 0.000
K51.5 Mucosal proctocolitis
0.768 0.232 0.000
I71.0 Dissection of aorta [any part]
0.768 0.232 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.768 0.232 0.000
H35.6 Retinal haemorrhage
0.766 0.234 0.000
E11.4 With neurological complications
0.766 0.234 0.000
M54.57 Low back pain (Lumbosacral region)
0.766 0.234 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.766 0.234 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.766 0.234 0.000
K65-K67 Diseases of peritoneum
0.765 0.235 0.000
H35.0 Background retinopathy and retinal vascular changes
0.764 0.236 0.000
N99-N99 Other disorders of the genitourinary system
0.762 0.238 0.000
H35.9 Retinal disorder, unspecified
0.761 0.239 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.760 0.240 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.760 0.240 0.000
A04 Other bacterial intestinal infections
0.760 0.240 0.000
M75.0 Adhesive capsulitis of shoulder
0.759 0.241 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.758 0.242 0.000
S01.9 Open wound of head, part unspecified
0.757 0.242 0.000
E11.2 With renal complications
0.757 0.243 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.757 0.243 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.756 0.244 0.000
Z35 Supervision of high-risk pregnancy
0.756 0.244 0.000
E65-E68 Obesity and other hyperalimentation
0.754 0.246 0.000
L03.1 Cellulitis of other parts of limb
0.754 0.246 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.753 0.247 0.000
M54.4 Lumbago with sciatica
0.753 0.247 0.000
H25.1 Senile nuclear cataract
0.753 0.247 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.749 0.251 0.000
R45 Symptoms and signs involving emotional state
0.749 0.251 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.748 0.251 0.000
M72 Fibroblastic disorders
0.748 0.251 0.000
A80-A89 Viral infections of the central nervous system
0.748 0.252 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.747 0.253 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.745 0.255 0.000
Z30.2 Sterilisation
0.745 0.255 0.000
M91-M94 Chondropathies
0.744 0.256 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.744 0.256 0.000
E83 Disorders of mineral metabolism
0.742 0.258 0.000
M51.2 Other specified intervertebral disk displacement
0.742 0.258 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.742 0.258 0.000
E88 Other metabolic disorders
0.741 0.259 0.000
H35.4 Peripheral retinal degeneration
0.740 0.260 0.000
M53 Other dorsopathies, not elsewhere classified
0.740 0.260 0.000
E13 Other specified diabetes mellitus
0.739 0.261 0.000
E40-E46 Malnutrition
0.739 0.261 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.738 0.262 0.000
T66-T78 Other and unspecified effects of external causes
0.738 0.262 0.000
R50-R69 General symptoms and signs
0.737 0.263 0.000
Z49.0 Preparatory care for dialysis
0.735 0.264 0.000
I45 Other conduction disorders
0.735 0.265 0.000
G30 Alzheimer's disease
0.735 0.265 0.000
M54.3 Sciatica
0.735 0.265 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.735 0.265 0.000
I12.9 Hypertensive renal disease without renal failure
0.733 0.266 0.000
S80-S89 Injuries to the knee and lower leg
0.732 0.268 0.000
N73 Other female pelvic inflammatory diseases
0.731 0.269 0.000
H10-H13 Disorders of conjunctiva
0.730 0.269 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.730 0.270 0.000
Z34 Supervision of normal pregnancy
0.730 0.270 0.000
M54.50 Low back pain (Multiple sites in spine)
0.730 0.270 0.000
I33 Acute and subacute endocarditis
0.729 0.271 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.728 0.272 0.000
Z29 Need for other prophylactic measures
0.728 0.272 0.000
L27 Dermatitis due to substances taken internally
0.728 0.272 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.728 0.272 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.728 0.272 0.000
H81 Disorders of vestibular function
0.727 0.273 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.726 0.274 0.000
H43-H45 Disorders of vitreous body and globe
0.725 0.275 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.724 0.276 0.000
M77 Other enthesopathies
0.724 0.276 0.000
K62.4 Stenosis of anus and rectum
0.723 0.277 0.000
Z22 Carrier of infectious disease
0.722 0.278 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.722 0.278 0.000
M71 Other bursopathies
0.722 0.278 0.000
K63 Other diseases of intestine
0.722 0.278 0.000
K58 Irritable bowel syndrome
0.722 0.278 0.000
K90-K93 Other diseases of the digestive system
0.722 0.278 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.720 0.280 0.000
I69 Sequelae of cerebrovascular disease
0.720 0.280 0.000
K56.7 Ileus, unspecified
0.720 0.280 0.000
I42 Cardiomyopathy
0.720 0.280 0.000
M84 Disorders of continuity of bone
0.719 0.280 0.000
G90-G99 Other disorders of the nervous system
0.718 0.282 0.000
M75.5 Bursitis of shoulder
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.6 With other specified complications
0.717 0.283 0.000
E11.1 With ketoacidosis
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.716 0.283 0.000
I72 Other aneurysm
0.716 0.283 0.000
I70 Atherosclerosis
0.716 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
Z57.2 Occupational exposure to dust
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
H33 Retinal detachments and breaks
0.716 0.284 0.000
H66 Suppurative and unspecified otitis media
0.716 0.284 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.716 0.284 0.000
K51.2 Ulcerative (chronic) proctitis
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
L50-L54 Urticaria and erythema
0.715 0.285 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
S06 Intracranial injury
0.714 0.286 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.712 0.288 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.712 0.288 0.000
E78.8 Other disorders of lipoprotein metabolism
0.712 0.288 0.000
E78.6 Lipoprotein deficiency
0.712 0.288 0.000
E78.4 Other hyperlipidaemia
0.712 0.288 0.000
E78.3 Hyperchylomicronaemia
0.712 0.288 0.000
E78.1 Pure hyperglyceridaemia
0.712 0.288 0.000
N76.0 Acute vaginitis
0.712 0.288 0.000
R07.1 Chest pain on breathing
0.712 0.288 0.000
N00-N08 Glomerular diseases
0.712 0.288 0.000
R27 Other lack of coordination
0.711 0.289 0.000
R40 Somnolence, stupor and coma
0.711 0.289 0.000
Z51 Other medical care
0.709 0.291 0.000
H00 Hordeolum and chalazion
0.709 0.291 0.000
I34 Nonrheumatic mitral valve disorders
0.709 0.291 0.000
E10.5 With peripheral circulatory complications
0.708 0.292 0.000
H40 Glaucoma
0.708 0.292 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.707 0.292 0.000
R46 Symptoms and signs involving appearance and behaviour
0.707 0.293 0.000
R43 Disturbances of smell and taste
0.707 0.293 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.707 0.293 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I37 Pulmonary valve disorders
0.707 0.293 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
I30 Acute pericarditis
0.707 0.293 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.706 0.294 0.000
K52 Other non-infective gastro-enteritis and colitis
0.706 0.294 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.706 0.294 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.706 0.294 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.705 0.295 0.000
H31 Other disorders of choroid
0.705 0.295 0.000
H30 Chorioretinal inflammation
0.705 0.295 0.000
I73.8 Other specified peripheral vascular diseases
0.704 0.295 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.704 0.295 0.000
M76 Enthesopathies of lower limb, excluding foot
0.704 0.295 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.704 0.295 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.704 0.295 0.000
E10.2 With renal complications
0.704 0.295 0.000
L29 Pruritus
0.704 0.296 0.000
R00 Abnormalities of heart beat
0.704 0.296 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.704 0.296 0.000
B25-B34 Other viral diseases
0.704 0.296 0.000
Z42 Follow-up care involving plastic surgery
0.704 0.296 0.000
Z54 Convalescence
0.703 0.296 0.000
Z52 Donors of organs and tissues
0.703 0.296 0.000
Z44 Fitting and adjustment of external prosthetic device
0.703 0.296 0.000
Z41 Procedures for purposes other than remedying health state
0.703 0.297 0.000
K51.4 Pseudopolyposis of colon
0.702 0.298 0.000
G70-G73 Diseases of myoneural junction and muscle
0.702 0.298 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.702 0.298 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.702 0.298 0.000
H69 Other disorders of Eustachian tube
0.701 0.299 0.000
M54.8 Other dorsalgia
0.701 0.299 0.000
M54.6 Pain in thoracic spine
0.701 0.299 0.000
M54.0 Panniculitis affecting regions of neck and back
0.701 0.299 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.701 0.299 0.000
H53-H54 Visual disturbances and blindness
0.700 0.300 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.700 0.300 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.699 0.301 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.697 0.303 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.697 0.303 0.000
I51.6 Cardiovascular disease, unspecified
0.696 0.304 0.000
I51.5 Myocardial degeneration
0.696 0.304 0.000
I51.4 Myocarditis, unspecified
0.696 0.304 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.696 0.304 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.696 0.304 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.696 0.304 0.000
I51.0 Cardiac septal defect, acquired
0.696 0.304 0.000
L05.0 Pilonidal cyst with abscess
0.696 0.304 0.000
I95.9 Hypotension, unspecified
0.696 0.304 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.696 0.304 0.000
G44 Other headache syndromes
0.696 0.304 0.000
G41 Status epilepticus
0.696 0.304 0.000
S02 Fracture of skull and facial bones
0.695 0.305 0.000
K62.7 Radiation proctitis
0.694 0.306 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.693 0.307 0.000
H04 Disorders of lachrymal system
0.693 0.307 0.000
H90-H95 Other disorders of ear
0.692 0.308 0.000
Chapter V Mental and behavioural disorders
0.691 0.309 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.691 0.309 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.691 0.309 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.691 0.309 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.691 0.309 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.691 0.309 0.000
M81 Osteoporosis without pathological fracture
0.690 0.310 0.000
Chapter XX External causes of morbidity and mortality
0.690 0.310 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.689 0.311 0.000
A41.8 Other specified septicaemia
0.688 0.312 0.000
N10-N16 Renal tubulo-interstitial diseases
0.688 0.312 0.000
H55 Nystagmus and other irregular eye movements
0.687 0.313 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.687 0.313 0.000
R06 Abnormalities of breathing
0.687 0.313 0.000
K55.9 Vascular disorder of intestine, unspecified
0.687 0.313 0.000
M79.9 Soft tissue disorder, unspecified
0.686 0.314 0.000
M79.5 Residual foreign body in soft tissue
0.686 0.314 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.686 0.314 0.000
M79.3 Panniculitis, unspecified
0.686 0.314 0.000
M79.2 Neuralgia and neuritis, unspecified
0.686 0.314 0.000
M79.1 Myalgia
0.686 0.314 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.686 0.314 0.000
G43.9 Migraine, unspecified
0.685 0.315 0.000
I49 Other cardiac arrhythmias
0.684 0.316 0.000
H35.7 Separation of retinal layers
0.684 0.316 0.000
H35.5 Hereditary retinal dystrophy
0.684 0.316 0.000
H35.2 Other proliferative retinopathy
0.684 0.316 0.000
H35.1 Retinopathy of prematurity
0.684 0.316 0.000
R53 Malaise and fatigue
0.684 0.316 0.000
S70-S79 Injuries to the hip and thigh
0.683 0.317 0.000
E86 Volume depletion
0.683 0.317 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.681 0.319 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.680 0.320 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.679 0.321 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.679 0.321 0.000
K56.4 Other impaction of intestine
0.679 0.321 0.000
A48 Other bacterial diseases, not elsewhere classified
0.678 0.322 0.000
A44 Bartonellosis
0.678 0.322 0.000
A43 Nocardiosis
0.678 0.322 0.000
A42 Actinomycosis
0.678 0.322 0.000
A39 Meningococcal infection
0.678 0.322 0.000
A37 Whooping cough
0.678 0.322 0.000
A36 Diphtheria
0.678 0.322 0.000
A32 Listeriosis
0.678 0.322 0.000
A31 Infection due to other mycobacteria
0.678 0.322 0.000
A30 Leprosy [Hansen's disease]
0.678 0.322 0.000
A46 Erysipelas
0.678 0.322 0.000
A38 Scarlet fever
0.678 0.322 0.000
A35 Other tetanus
0.678 0.322 0.000
A34 Obstetrical tetanus
0.678 0.322 0.000
A33 Tetanus neonatorum
0.678 0.322 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.678 0.322 0.000
A49.1 Streptococcal infection, unspecified
0.677 0.323 0.000
H34.8 Other retinal vascular occlusions
0.676 0.324 0.000
L04 Acute lymphadenitis
0.676 0.324 0.000
L01 Impetigo
0.676 0.324 0.000
L00 Staphylococcal scalded skin syndrome
0.676 0.324 0.000
N71 Inflammatory disease of uterus, except cervix
0.676 0.324 0.000
E22 Hyperfunction of pituitary gland
0.676 0.324 0.000
H01 Other inflammation of eyelid
0.675 0.324 0.000
I84 Haemorrhoids
0.676 0.324 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.675 0.325 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.675 0.325 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.675 0.325 0.000
M86-M90 Other osteopathies
0.675 0.325 0.000
K62.2 Anal prolapse
0.674 0.325 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.674 0.326 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.674 0.326 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.674 0.326 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.674 0.326 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.673 0.326 0.000
M80 Osteoporosis with pathological fracture
0.673 0.326 0.000
R01 Cardiac murmurs and other cardiac sounds
0.673 0.327 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.673 0.327 0.000
G45.3 Amaurosis fugax
0.673 0.327 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.673 0.327 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.673 0.327 0.000
G45.0 Vertebro-basilar artery syndrome
0.673 0.327 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.673 0.327 0.000
Z53.8 Procedure not carried out for other reasons
0.672 0.328 0.000
G30.9 Alzheimer's disease, unspecified
0.672 0.328 0.000
R76 Other abnormal immunological findings in serum
0.672 0.328 0.000
M54.55 Low back pain (Thoracolumbar region)
0.672 0.328 0.000
M54.54 Low back pain-Thoracic
0.672 0.328 0.000
M54.53 Low back pain-Cervicothoracic
0.672 0.328 0.000
M54.52 Low back pain-Cervical
0.672 0.328 0.000
M54.51 Low back pain-Occipit-atl-axl
0.672 0.328 0.000
Z49.2 Other dialysis
0.671 0.329 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.671 0.329 0.000
R77 Other abnormalities of plasma proteins
0.671 0.329 0.000
R74 Abnormal serum enzyme levels
0.671 0.329 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.671 0.329 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.671 0.329 0.000
R71 Abnormality of red blood cells
0.671 0.329 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.670 0.329 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.670 0.329 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.670 0.329 0.000
I65.1 Occlusion and stenosis of basilar artery
0.670 0.329 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.670 0.329 0.000
H83 Other diseases of inner ear
0.670 0.330 0.000
I77.8 Other specified disorders of arteries and arterioles
0.670 0.330 0.000
N17-N19 Renal failure
0.670 0.330 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.670 0.330 0.000
I63 Cerebral infarction
0.669 0.331 0.000
K51.8 Other ulcerative colitis
0.668 0.332 0.000
E23 Hypofunction and other disorders of pituitary gland
0.668 0.332 0.000
S01.2 Open wound of nose
0.667 0.333 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.667 0.333 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.667 0.333 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
S01.1 Open wound of eyelid and periocular area
0.667 0.333 0.000
Z36 Antenatal screening
0.666 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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