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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16892807
log Bayes Factor = 11.3319
Chromosome 8   position 120,590,177  (GRCh37) Explore rs16892807 on Ensembl!
Variant rs16892807 is part of Cluster X0084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
B95-B98 Bacterial, viral and other infectious agents
0.996 0.004 0.000
S80-S89 Injuries to the knee and lower leg
0.994 0.006 0.000
H53-H54 Visual disturbances and blindness
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
H54 Blindness and low vision
0.993 0.007 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.993 0.007 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.990 0.010 0.000
R29.6 Tendency to fall, not elsewhere classified
0.989 0.011 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
B35-B49 Mycoses
0.981 0.019 0.000
M06 Other rheumatoid arthritis
0.979 0.021 0.000
B37 Candidiasis
0.973 0.027 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.971 0.029 0.000
M80-M85 Disorders of bone density and structure
0.970 0.030 0.000
R30-R39 Symptoms and signs involving the urinary system
0.969 0.031 0.000
S80 Superficial injury of lower leg
0.966 0.034 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.965 0.035 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.962 0.038 0.000
F10.0 Acute intoxication
0.960 0.040 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.960 0.040 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.958 0.042 0.000
M06.9 Rheumatoid arthritis, unspecified
0.955 0.045 0.000
H54.4 Blindness, one eye
0.953 0.047 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.950 0.050 0.000
M84 Disorders of continuity of bone
0.948 0.052 0.000
F10.2 Dependence syndrome
0.945 0.055 0.000
B37.8 Candidiasis of other sites
0.944 0.056 0.000
R47-R49 Symptoms and signs involving speech and voice
0.942 0.058 0.000
H55-H59 Other disorders of eye and adnexa
0.938 0.062 0.000
M06.0 Seronegative rheumatoid arthritis
0.936 0.064 0.000
S00-S09 Injuries to the head
0.935 0.065 0.000
H54.9 Unspecified visual impairment (binocular)
0.931 0.069 0.000
R25 Abnormal involuntary movements
0.925 0.075 0.000
Y95 Nosocomial condition
0.924 0.076 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.921 0.079 0.000
H54.0 Blindness, both eyes
0.913 0.087 0.000
S50-S59 Injuries to the elbow and forearm
0.913 0.087 0.000
M86-M90 Other osteopathies
0.912 0.088 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.911 0.089 0.000
R47 Speech disturbances, not elsewhere classified
0.911 0.089 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.910 0.090 0.000
M65-M68 Disorders of synovium and tendon
0.910 0.090 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.909 0.090 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.908 0.092 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.902 0.098 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.900 0.100 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.898 0.102 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.893 0.107 0.000
H54.7 Unspecified visual loss
0.893 0.107 0.000
R35 Polyuria
0.892 0.108 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.892 0.108 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.890 0.110 0.000
H30-H36 Disorders of choroid and retina
0.886 0.114 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.884 0.116 0.000
R47.8 Other and unspecified speech disturbances
0.883 0.117 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.882 0.118 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.881 0.119 0.000
B15-B19 Viral hepatitis
0.877 0.122 0.000
S90-S99 Injuries to the ankle and foot
0.874 0.126 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.865 0.135 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.865 0.135 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.861 0.139 0.000
S80.9 Superficial injury of lower leg, unspecified
0.860 0.140 0.000
F01 Vascular dementia
0.856 0.144 0.000
F03 Unspecified dementia
0.854 0.146 0.000
M84.0 Malunion of fracture
0.854 0.146 0.000
S81 Open wound of lower leg
0.852 0.148 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.852 0.148 0.000
R25.1 Tremor, unspecified
0.849 0.151 0.000
R26 Abnormalities of gait and mobility
0.848 0.152 0.000
M67 Other disorders of synovium and tendon
0.847 0.153 0.000
Chapter XXII Codes for special purposes
0.846 0.154 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.846 0.154 0.000
S01 Open wound of head
0.843 0.157 0.000
M89 Other disorders of bone
0.841 0.159 0.000
Chapter VI Diseases of the nervous system
0.841 0.159 0.000
S80.8 Other superficial injuries of lower leg
0.840 0.160 0.000
B37.3 Candidiasis of vulva and vagina
0.835 0.165 0.000
H20 Iridocyclitis
0.835 0.165 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.834 0.166 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.833 0.167 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.832 0.168 0.000
R32 Unspecified urinary incontinence
0.828 0.172 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.825 0.175 0.000
S80.0 Contusion of knee
0.825 0.175 0.000
M85 Other disorders of bone density and structure
0.825 0.175 0.000
B37.0 Candidal stomatitis
0.818 0.182 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.818 0.182 0.000
H35 Other retinal disorders
0.818 0.182 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.817 0.183 0.000
M67.8 Other specified disorders of synovium and tendon
0.813 0.187 0.000
S52 Fracture of forearm
0.809 0.191 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.808 0.192 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.806 0.194 0.000
F10.6 Amnesic syndrome
0.806 0.194 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.805 0.195 0.000
R33 Retention of urine
0.805 0.195 0.000
T79-T79 Certain early complications of trauma
0.803 0.197 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.802 0.198 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.800 0.200 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.800 0.200 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.799 0.201 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.798 0.202 0.000
F10.3 Withdrawal state
0.798 0.202 0.000
B37.4 Candidiasis of other urogenital sites
0.798 0.202 0.000
B37.1 Pulmonary candidiasis
0.798 0.202 0.000
S40-S49 Injuries to the shoulder and upper arm
0.793 0.207 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.792 0.208 0.000
G20-G26 Extrapyramidal and movement disorders
0.791 0.209 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.790 0.210 0.000
H57 Other disorders of eye and adnexa
0.790 0.210 0.000
M10 Gout
0.789 0.211 0.000
W00-W19 Falls
0.789 0.211 0.000
M84.03 Malunion of fracture (Forearm)
0.787 0.213 0.000
M89.9 Disorder of bone, unspecified
0.786 0.214 0.000
T00-T07 Injuries involving multiple body regions
0.786 0.214 0.000
M11 Other crystal arthropathies
0.785 0.215 0.000
R77 Other abnormalities of plasma proteins
0.785 0.215 0.000
B44 Aspergillosis
0.783 0.217 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.781 0.219 0.000
R31 Unspecified haematuria
0.781 0.219 0.000
R39 Other symptoms and signs involving the urinary system
0.780 0.220 0.000
S06 Intracranial injury
0.780 0.220 0.000
R76 Other abnormal immunological findings in serum
0.779 0.221 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.779 0.221 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.779 0.221 0.000
F01.9 Vascular dementia, unspecified
0.777 0.223 0.000
M60-M63 Disorders of muscles
0.776 0.223 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.775 0.224 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.775 0.225 0.000
G82 Paraplegia and tetraplegia
0.775 0.225 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.772 0.228 0.000
T86 Failure and rejection of transplanted organs and tissues
0.771 0.229 0.000
F02 Dementia in other diseases classified elsewhere
0.770 0.230 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.769 0.231 0.000
S00 Superficial injury of head
0.769 0.231 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.769 0.231 0.000
S81.8 Open wound of other parts of lower leg
0.767 0.233 0.000
H10-H13 Disorders of conjunctiva
0.767 0.233 0.000
F80-F89 Disorders of psychological development
0.766 0.234 0.000
H46 Optic neuritis
0.766 0.234 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.764 0.236 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.763 0.237 0.000
M84.4 Pathological fracture, not elsewhere classified
0.763 0.237 0.000
F60-F69 Disorders of adult personality and behaviour
0.762 0.238 0.000
R47.0 Dysphasia and aphasia
0.760 0.240 0.000
W50-W64 Exposure to animate mechanical forces
0.760 0.240 0.000
B50-B64 Protozoal diseases
0.760 0.240 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.760 0.240 0.000
B65-B83 Helminthiases
0.760 0.240 0.000
S91 Open wound of ankle and foot
0.760 0.240 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.760 0.240 0.000
S86 Injury of muscle and tendon at lower leg level
0.759 0.241 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.758 0.242 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.757 0.243 0.000
H20.9 Iridocyclitis, unspecified
0.756 0.244 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.755 0.245 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.754 0.246 0.000
V40-V49 Car occupant injured in transport accident
0.753 0.247 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.753 0.247 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.752 0.248 0.000
T87 Complications peculiar to reattachment and amputation
0.751 0.249 0.000
S60-S69 Injuries to the wrist and hand
0.750 0.250 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.749 0.251 0.000
B17 Other acute viral hepatitis
0.749 0.251 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.748 0.252 0.000
G20 Parkinson's disease
0.748 0.252 0.000
F70-F79 Mental retardation
0.747 0.253 0.000
X20-X29 Contact with venomous animals and plants
0.745 0.255 0.000
Y85 Sequelae of transport accidents
0.743 0.257 0.000
F99-F99 Unspecified mental disorder
0.743 0.257 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.743 0.257 0.000
M91-M94 Chondropathies
0.740 0.260 0.000
X50-X57 Overexertion, travel and privation
0.740 0.260 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.739 0.261 0.000
T66-T78 Other and unspecified effects of external causes
0.739 0.261 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.739 0.261 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.739 0.261 0.000
H55 Nystagmus and other irregular eye movements
0.738 0.262 0.000
F10.9 Unspecified mental and behavioural disorder
0.737 0.263 0.000
S02 Fracture of skull and facial bones
0.736 0.264 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.736 0.264 0.000
S89 Other and unspecified injuries of lower leg
0.735 0.265 0.000
T42.4 Benzodiazepines
0.735 0.265 0.000
M07 Psoriatic and enteropathic arthropathies
0.733 0.267 0.000
Q80-Q89 Other congenital malformations
0.730 0.269 0.000
R73 Elevated blood glucose level
0.730 0.270 0.000
X10-X19 Contact with heat and hot substances
0.729 0.271 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.728 0.272 0.000
S50 Superficial injury of forearm
0.725 0.275 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.725 0.275 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.724 0.276 0.000
H21 Other disorders of iris and ciliary body
0.724 0.276 0.000
F10.4 Withdrawal state with delirium
0.723 0.277 0.000
H35.3 Degeneration of macula and posterior pole
0.723 0.277 0.000
S42 Fracture of shoulder and upper arm
0.720 0.280 0.000
S82 Fracture of lower leg, including ankle
0.720 0.280 0.000
M05 Seropositive rheumatoid arthritis
0.719 0.281 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.719 0.281 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.719 0.281 0.000
S01.1 Open wound of eyelid and periocular area
0.719 0.281 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
S52.6 Fracture of lower end of both ulna and radius
0.716 0.284 0.000
M70-M79 Other soft tissue disorders
0.716 0.284 0.000
M90 Osteopathies in diseases classified elsewhere
0.715 0.285 0.000
R25.3 Fasciculation
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
S01.8 Open wound of other parts of head
0.714 0.286 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.714 0.286 0.000
S88 Traumatic amputation of lower leg
0.713 0.287 0.000
S87 Crushing injury of lower leg
0.713 0.287 0.000
S85 Injury of blood vessels at lower leg level
0.713 0.287 0.000
S84 Injury of nerves at lower leg level
0.713 0.287 0.000
H54.6 Unqualified visual loss, one eye
0.712 0.288 0.000
H54.5 Low vision, one eye
0.712 0.288 0.000
H54.3 Unqualified visual loss, both eyes
0.712 0.288 0.000
H54.2 Low vision, both eyes
0.712 0.288 0.000
H54.1 Blindness, one eye, low vision, other eye
0.712 0.288 0.000
R29.4 Clicking hip
0.712 0.288 0.000
R29.3 Abnormal posture
0.712 0.288 0.000
R29.2 Abnormal reflex
0.712 0.288 0.000
R29.1 Meningismus
0.712 0.288 0.000
R29.0 Tetany
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
G81 Hemiplegia
0.711 0.289 0.000
R34 Anuria and oliguria
0.710 0.290 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.709 0.290 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.709 0.290 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.709 0.290 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.709 0.290 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.709 0.290 0.000
F11 Mental and behavioural disorders due to use of opioids
0.709 0.290 0.000
B18 Chronic viral hepatitis
0.709 0.291 0.000
R25.2 Cramp and spasm
0.709 0.291 0.000
F10.8 Other mental and behavioural disorders
0.708 0.292 0.000
F10.7 Residual and late-onset psychotic disorder
0.708 0.292 0.000
F10.5 Psychotic disorder
0.708 0.292 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.707 0.292 0.000
M66 Spontaneous rupture of synovium and tendon
0.707 0.293 0.000
M12 Other specific arthropathies
0.706 0.294 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.294 0.000
M08 Juvenile arthritis
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
R45 Symptoms and signs involving emotional state
0.706 0.294 0.000
H35.9 Retinal disorder, unspecified
0.704 0.296 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.704 0.296 0.000
R26.0 Ataxic gait
0.704 0.296 0.000
B48 Other mycoses, not elsewhere classified
0.703 0.297 0.000
B47 Mycetoma
0.703 0.297 0.000
B46 Zygomycosis
0.703 0.297 0.000
B45 Cryptococcosis
0.703 0.297 0.000
B43 Chromomycosis and phaeomycotic abscess
0.703 0.297 0.000
B42 Sporotrichosis
0.703 0.297 0.000
B41 Paracoccidioidomycosis
0.703 0.297 0.000
B40 Blastomycosis
0.703 0.297 0.000
B39 Histoplasmosis
0.703 0.297 0.000
B38 Coccidioidomycosis
0.703 0.297 0.000
B36 Other superficial mycoses
0.703 0.297 0.000
M85.8 Other specified disorders of bone density and structure
0.703 0.297 0.000
T21 Burn and corrosion of trunk
0.702 0.298 0.000
B99-B99 Other infectious diseases
0.702 0.298 0.000
M06.8 Other specified rheumatoid arthritis
0.702 0.298 0.000
M06.2 Rheumatoid bursitis
0.702 0.298 0.000
M06.1 Adult-onset Still's disease
0.702 0.298 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.702 0.298 0.000
S52.0 Fracture of upper end of ulna
0.700 0.300 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.700 0.300 0.000
S51 Open wound of forearm
0.699 0.301 0.000
B37.7 Candidal septicaemia
0.697 0.303 0.000
B37.6 Candidal endocarditis
0.697 0.303 0.000
B37.5 Candidal meningitis
0.697 0.303 0.000
B37.2 Candidiasis of skin and nail
0.697 0.303 0.000
M80 Osteoporosis with pathological fracture
0.697 0.303 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.696 0.304 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.696 0.304 0.000
M87 Osteonecrosis
0.696 0.304 0.000
M83 Adult osteomalacia
0.696 0.304 0.000
M82 Osteoporosis in diseases classified elsewhere
0.696 0.304 0.000
R36 Urethral discharge
0.695 0.305 0.000
S06.8 Other intracranial injuries
0.694 0.306 0.000
S01.9 Open wound of head, part unspecified
0.694 0.306 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.693 0.307 0.000
S80.7 Multiple superficial injuries of lower leg
0.693 0.307 0.000
R71 Abnormality of red blood cells
0.692 0.308 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.692 0.308 0.000
F09 Unspecified organic or symptomatic mental disorder
0.692 0.308 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.308 0.000
H20.1 Chronic iridocyclitis
0.691 0.309 0.000
S00.0 Superficial injury of scalp
0.691 0.309 0.000
M14 Arthropathies in other diseases classified elsewhere
0.687 0.313 0.000
R27 Other lack of coordination
0.687 0.313 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.687 0.313 0.000
Y98 Lifestyle-related condition
0.687 0.313 0.000
Y97 Environmental-pollution-related condition
0.687 0.313 0.000
Y96 Work-related condition
0.687 0.313 0.000
H30 Chorioretinal inflammation
0.686 0.314 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.685 0.315 0.000
G30-G32 Other degenerative diseases of the nervous system
0.685 0.315 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.684 0.315 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.684 0.315 0.000
S01.7 Multiple open wounds of head
0.684 0.316 0.000
S92 Fracture of foot, except ankle
0.683 0.317 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.683 0.317 0.000
G82.1 Spastic paraplegia
0.682 0.318 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.682 0.318 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.682 0.318 0.000
M72 Fibroblastic disorders
0.680 0.320 0.000
M84.9 Disorder of continuity of bone, unspecified
0.680 0.320 0.000
M84.8 Other disorders of continuity of bone
0.680 0.320 0.000
M84.3 Stress fracture, not elsewhere classified
0.680 0.320 0.000
M84.2 Delayed union of fracture
0.680 0.320 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.680 0.320 0.000
Q50-Q56 Congenital malformations of genital organs
0.679 0.321 0.000
X60-X84 Intentional self-harm
0.679 0.321 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.677 0.322 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.677 0.323 0.000
S10-S19 Injuries to the neck
0.676 0.324 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.675 0.325 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.675 0.325 0.000
M00-M03 Infectious arthropathies
0.675 0.325 0.000
R74 Abnormal serum enzyme levels
0.674 0.325 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.674 0.326 0.000
H35.8 Other specified retinal disorders
0.674 0.326 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.674 0.326 0.000
W20-W49 Exposure to inanimate mechanical forces
0.673 0.327 0.000
T23 Burn and corrosion of wrist and hand
0.672 0.328 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.671 0.329 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.671 0.329 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.671 0.329 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.671 0.329 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.671 0.329 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.671 0.329 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.671 0.329 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.671 0.329 0.000
V80-V89 Other land transport accidents
0.671 0.329 0.000
S08 Traumatic amputation of part of head
0.670 0.330 0.000
S07 Crushing injury of head
0.670 0.330 0.000
S04 Injury of cranial nerves
0.670 0.330 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.670 0.330 0.000
M06.4 Inflammatory polyarthropathy
0.670 0.330 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.670 0.330 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.668 0.332 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.668 0.332 0.000
Q60-Q64 Congenital malformations of the urinary system
0.667 0.333 0.000
G82.5 Tetraplegia, unspecified
0.667 0.333 0.000
H35.2 Other proliferative retinopathy
0.666 0.333 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.666 0.334 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.666 0.334 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.666 0.334 0.000
B00 Herpesviral [herpes simplex] infections
0.665 0.335 0.000
R25.0 Abnormal head movements
0.663 0.337 0.000
Q23 Congenital malformations of aortic and mitral valves
0.663 0.337 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.662 0.338 0.000
M06.3 Rheumatoid nodule
0.662 0.338 0.000
H47.1 Papilloedema, unspecified
0.662 0.338 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.662 0.338 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.662 0.338 0.000
W08 Fall involving other furniture
0.661 0.339 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.661 0.339 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.660 0.340 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.660 0.340 0.000
Y57 Other and unspecified drugs and medicaments
0.658 0.341 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.658 0.342 0.000
V10-V19 Pedal cyclist injured in transport accident
0.657 0.343 0.000
R77.8 Other specified abnormalities of plasma proteins
0.657 0.343 0.000
B17.1 Acute hepatitis C
0.656 0.344 0.000
F10.1 Harmful use
0.656 0.344 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.655 0.344 0.000
Y85.0 Sequelae of motor-vehicle accident
0.655 0.345 0.000
S59 Other and unspecified injuries of forearm
0.654 0.345 0.000
S58 Traumatic amputation of forearm
0.654 0.345 0.000
S57 Crushing injury of forearm
0.654 0.345 0.000
S56 Injury of muscle and tendon at forearm level
0.654 0.345 0.000
S55 Injury of blood vessels at forearm level
0.654 0.345 0.000
S54 Injury of nerves at forearm level
0.654 0.345 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.654 0.345 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.654 0.346 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.653 0.347 0.000
Q35-Q37 Cleft lip and cleft palate
0.653 0.347 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.653 0.347 0.000
Y52 Agents primarily affecting the cardiovascular system
0.653 0.347 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.652 0.348 0.000
M88 Paget's disease of bone [osteitis deformans]
0.652 0.348 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.651 0.349 0.000
Q27 Other congenital malformations of peripheral vascular system
0.651 0.349 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.650 0.350 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.650 0.350 0.000
M10.9 Gout, unspecified
0.649 0.351 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.648 0.352 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.648 0.352 0.000
R76.8 Other specified abnormal immunological findings in serum
0.648 0.352 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.648 0.352 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.648 0.352 0.000
S90 Superficial injury of ankle and foot
0.647 0.353 0.000
S70-S79 Injuries to the hip and thigh
0.645 0.355 0.000
R70.0 Elevated erythrocyte sedimentation rate
0.645 0.355 0.000
W10 Fall on and from stairs and steps
0.645 0.355 0.000
T20 Burn and corrosion of head and neck
0.645 0.355 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.644 0.356 0.000
M11.2 Other chondrocalcinosis
0.642 0.358 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.641 0.359 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.641 0.359 0.000
H15 Disorders of sclera
0.641 0.359 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.639 0.361 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.639 0.361 0.000
R45.8 Other symptoms and signs involving emotional state
0.639 0.361 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.638 0.361 0.000
S01.5 Open wound of lip and oral cavity
0.636 0.363 0.000
H20.0 Acute and subacute iridocyclitis
0.636 0.364 0.000
G81.9 Hemiplegia, unspecified
0.636 0.364 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.635 0.365 0.000
Y44 Agents primarily affecting blood constituents
0.635 0.365 0.000
T42.1 Iminostilbenes
0.635 0.365 0.000
S83.7 Injury to multiple structures of knee
0.634 0.366 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.634 0.366 0.000
S83.3 Tear of articular cartilage of knee, current
0.634 0.366 0.000
S83.1 Dislocation of knee
0.634 0.366 0.000
S83.0 Dislocation of patella
0.634 0.366 0.000
S52.1 Fracture of upper end of radius
0.634 0.366 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.633 0.367 0.000
T02 Fractures involving multiple body regions
0.633 0.367 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.633 0.367 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.632 0.367 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.632 0.367 0.000
H31 Other disorders of choroid
0.630 0.369 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.630 0.370 0.000
Q21 Congenital malformations of cardiac septa
0.630 0.370 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.630 0.370 0.000
S42.0 Fracture of clavicle
0.630 0.370 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.630 0.370 0.000
B19 Unspecified viral hepatitis
0.629 0.371 0.000
B16 Acute hepatitis B
0.629 0.371 0.000
B15 Acute hepatitis A
0.629 0.371 0.000
F05.9 Delirium, unspecified
0.629 0.371 0.000
H11 Other disorders of conjunctiva
0.629 0.371 0.000
T92 Sequelae of injuries of upper limb
0.628 0.372 0.000
S81.9 Open wound of lower leg, part unspecified
0.628 0.372 0.000
S91.0 Open wound of ankle
0.627 0.373 0.000
S98 Traumatic amputation of ankle and foot
0.627 0.373 0.000
S97 Crushing injury of ankle and foot
0.627 0.373 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.627 0.373 0.000
S95 Injury of blood vessels at ankle and foot level
0.627 0.373 0.000
S94 Injury of nerves at ankle and foot level
0.627 0.373 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.627 0.373 0.000
M89.3 Hypertrophy of bone
0.627 0.373 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.626 0.374 0.000
T91 Sequelae of injuries of neck and trunk
0.625 0.375 0.000
W87 Exposure to unspecified electric current
0.625 0.375 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.625 0.375 0.000
T31 Burns classified according to extent of body surface involved
0.625 0.375 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.624 0.376 0.000
Q00-Q07 Congenital malformations of the nervous system
0.623 0.376 0.000
H34 Retinal vascular occlusions
0.623 0.377 0.000
S82.3 Fracture of lower end of tibia
0.623 0.377 0.000
W05 Fall involving wheelchair
0.623 0.377 0.000
S52.00 Fracture of upper end of ulna (closed)
0.622 0.377 0.000
S40 Superficial injury of shoulder and upper arm
0.622 0.378 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.622 0.378 0.000
Q85 Phakomatoses, not elsewhere classified
0.622 0.378 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.622 0.378 0.000
M89.5 Osteolysis
0.621 0.379 0.000
Y88 Sequelae of surgical and medical care as external cause
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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