TreeWAS – Variant ID: rs7016880

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.006	0.994
I25 Chronic ischaemic heart disease	0.000	0.006	0.994
I20-I25 Ischaemic heart diseases	0.000	0.007	0.993
I21 Acute myocardial infarction	0.000	0.027	0.973
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.032	0.968
I24 Other acute ischaemic heart diseases	0.000	0.035	0.965
E78.0 Pure hypercholesterolaemia	0.000	0.067	0.933
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.071	0.929
E78.5 Hyperlipidaemia, unspecified	0.000	0.078	0.922
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.080	0.920
I25.2 Old myocardial infarction	0.000	0.084	0.916
I24.8 Other forms of acute ischaemic heart disease	0.000	0.088	0.912
I22 Subsequent myocardial infarction	0.000	0.104	0.896
I20 Angina pectoris	0.000	0.117	0.883
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.126	0.874
E78.2 Mixed hyperlipidaemia	0.000	0.155	0.845
I21.9 Acute myocardial infarction, unspecified	0.000	0.165	0.835
I20.9 Angina pectoris, unspecified	0.000	0.170	0.830
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.195	0.805
I25.4 Coronary artery aneurysm	0.000	0.208	0.792
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.209	0.791
I20.0 Unstable angina	0.000	0.228	0.772
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.272	0.728
E78.4 Other hyperlipidaemia	0.000	0.282	0.718
I25.6 Silent myocardial ischaemia	0.000	0.287	0.713
I23 Certain current complications following acute myocardial infarction	0.000	0.288	0.712
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.301	0.699
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.302	0.698
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.302	0.698
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.313	0.687
E78.6 Lipoprotein deficiency	0.000	0.334	0.666
E78.3 Hyperchylomicronaemia	0.000	0.334	0.666
E78.1 Pure hyperglyceridaemia	0.000	0.334	0.666
I24.1 Dressler's syndrome	0.000	0.344	0.656
I22.8 Subsequent myocardial infarction of other sites	0.000	0.371	0.629
E78.8 Other disorders of lipoprotein metabolism	0.000	0.375	0.625
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.378	0.622
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.380	0.620
I25.5 Ischaemic cardiomyopathy	0.000	0.429	0.571
I25.3 Aneurysm of heart	0.000	0.449	0.550
I23.8 Other current complications following acute myocardial infarction	0.000	0.489	0.510
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.489	0.510
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.489	0.510
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.489	0.510
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.489	0.510
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.489	0.510
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.489	0.510
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.489	0.510
I20.1 Angina pectoris with documented spasm	0.000	0.547	0.452
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.585	0.415
I20.8 Other forms of angina pectoris	0.000	0.603	0.397
I21.4 Acute subendocardial myocardial infarction	0.000	0.637	0.363
E70-E90 Metabolic disorders	0.000	0.863	0.137
I77 Other disorders of arteries and arterioles	0.000	0.871	0.129
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.871	0.129
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.879	0.121
I71 Aortic aneurysm and dissection	0.000	0.879	0.121
I77.1 Stricture of artery	0.000	0.882	0.118
I77.6 Arteritis, unspecified	0.000	0.882	0.118
I72 Other aneurysm	0.000	0.886	0.114
E83 Disorders of mineral metabolism	0.000	0.887	0.113
E83.1 Disorders of iron metabolism	0.000	0.889	0.111
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.891	0.109
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.892	0.108
E86 Volume depletion	0.000	0.892	0.108
I77.8 Other specified disorders of arteries and arterioles	0.000	0.892	0.108
Chapter IX Diseases of the circulatory system	0.000	0.893	0.107
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.895	0.105
I72.4 Aneurysm of artery of lower extremity	0.000	0.897	0.103
E73 Lactose intolerance	0.000	0.897	0.103
I70 Atherosclerosis	0.000	0.897	0.103
E74 Other disorders of carbohydrate metabolism	0.000	0.899	0.100
I74 Arterial embolism and thrombosis	0.000	0.901	0.099
E88 Other metabolic disorders	0.000	0.901	0.099
E84 Cystic fibrosis	0.000	0.902	0.098
E79 Disorders of purine and pyrimidine metabolism	0.000	0.902	0.098
E77 Disorders of glycoprotein metabolism	0.000	0.902	0.098
E76 Disorders of glycosaminoglycan metabolism	0.000	0.902	0.098
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.902	0.098
E72 Other disorders of amino-acid metabolism	0.000	0.902	0.098
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.902	0.098
E70 Disorders of aromatic amino-acid metabolism	0.000	0.902	0.098
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.902	0.098
I71.0 Dissection of aorta [any part]	0.000	0.903	0.097
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.903	0.097
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.905	0.094
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.906	0.094
I77.5 Necrosis of artery	0.000	0.907	0.093
I77.4 Coeliac artery compression syndrome	0.000	0.907	0.093
I77.3 Arterial fibromuscular dysplasia	0.000	0.907	0.093
I77.2 Rupture of artery	0.000	0.907	0.093
I72.3 Aneurysm of iliac artery	0.000	0.908	0.092
E85 Amyloidosis	0.000	0.910	0.090
I72.8 Aneurysm of other specified arteries	0.000	0.912	0.088
E83.4 Disorders of magnesium metabolism	0.000	0.913	0.087
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.913	0.087
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.913	0.087
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.913	0.087
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.913	0.087
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.913	0.087
I77.0 Arteriovenous fistula, acquired	0.000	0.913	0.087
I78 Diseases of capillaries	0.000	0.915	0.085
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.917	0.083
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.918	0.082
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.918	0.082
I72.1 Aneurysm of artery of upper extremity	0.000	0.918	0.082
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.918	0.082
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.919	0.081
E83.8 Other disorders of mineral metabolism	0.000	0.919	0.081
E83.2 Disorders of zinc metabolism	0.000	0.919	0.081
E83.0 Disorders of copper metabolism	0.000	0.919	0.081
I72.2 Aneurysm of renal artery	0.000	0.921	0.079
E73.9 Lactose intolerance, unspecified	0.000	0.921	0.079
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.922	0.078
I79.1 Aortitis in diseases classified elsewhere	0.000	0.922	0.078
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.922	0.078
I72.9 Aneurysm of unspecified site	0.000	0.922	0.078
I70.0 Atherosclerosis of aorta	0.000	0.922	0.077
I00-I02 Acute rheumatic fever	0.000	0.923	0.077
I74.5 Embolism and thrombosis of iliac artery	0.000	0.924	0.076
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.925	0.074
E73.8 Other lactose intolerance	0.000	0.926	0.074
E73.1 Secondary lactase deficiency	0.000	0.926	0.074
E73.0 Congenital lactase deficiency	0.000	0.926	0.074
I70.9 Generalised and unspecified atherosclerosis	0.000	0.926	0.074
I70.8 Atherosclerosis of other arteries	0.000	0.926	0.074
I70.1 Atherosclerosis of renal artery	0.000	0.926	0.074
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.928	0.072
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.928	0.072
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.928	0.072
E74.2 Disorders of galactose metabolism	0.000	0.928	0.072
E74.1 Disorders of fructose metabolism	0.000	0.928	0.072
E74.0 Glycogen storage disease	0.000	0.928	0.072
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.928	0.072
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.928	0.072
I74.8 Embolism and thrombosis of other arteries	0.000	0.929	0.071
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.929	0.071
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.929	0.071
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.929	0.071
E88.9 Metabolic disorder, unspecified	0.000	0.929	0.071
E88.8 Other specified metabolic disorders	0.000	0.929	0.071
E88.3 Tumour lysis syndrome	0.000	0.929	0.071
E88.2 Lipomatosis, not elsewhere classified	0.000	0.929	0.071
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.929	0.071
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.929	0.070
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.929	0.070
E70.3 Albinism	0.000	0.929	0.070
E70.2 Disorders of tyrosine metabolism	0.000	0.929	0.070
E70.1 Other hyperphenylalaninaemias	0.000	0.929	0.070
E70.0 Classical phenylketonuria	0.000	0.929	0.070
E71.3 Disorders of fatty-acid metabolism	0.000	0.929	0.070
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.929	0.070
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.929	0.070
E71.0 Maple-syrup-urine disease	0.000	0.929	0.070
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.929	0.070
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.929	0.070
E72.5 Disorders of glycine metabolism	0.000	0.929	0.070
E72.4 Disorders of ornithine metabolism	0.000	0.929	0.070
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.929	0.070
E72.2 Disorders of urea cycle metabolism	0.000	0.929	0.070
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.929	0.070
E72.0 Disorders of amino-acid transport	0.000	0.929	0.070
E75.6 Lipid storage disorder, unspecified	0.000	0.929	0.070
E75.5 Other lipid storage disorders	0.000	0.929	0.070
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.929	0.070
E75.3 Sphingolipidosis, unspecified	0.000	0.929	0.070
E75.2 Other sphingolipidosis	0.000	0.929	0.070
E75.1 Other gangliosidosis	0.000	0.929	0.070
E75.0 GM2 gangliosidosis	0.000	0.929	0.070
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.929	0.070
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.929	0.070
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.929	0.070
E76.2 Other mucopolysaccharidoses	0.000	0.929	0.070
E76.1 Mucopolysaccharidosis, type II	0.000	0.929	0.070
E76.0 Mucopolysaccharidosis, type I	0.000	0.929	0.070
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.929	0.070
E77.8 Other disorders of glycoprotein metabolism	0.000	0.929	0.070
E77.1 Defects in glycoprotein degradation	0.000	0.929	0.070
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.929	0.070
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.929	0.070
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.929	0.070
E79.1 Lesch-Nyhan syndrome	0.000	0.929	0.070
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.929	0.070
E84.9 Cystic fibrosis, unspecified	0.000	0.929	0.070
E84.8 Cystic fibrosis with other manifestations	0.000	0.929	0.070
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.929	0.070
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.929	0.070
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.932	0.068
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.933	0.067
E85.4 Organ-limited amyloidosis	0.000	0.933	0.066
E85.8 Other amyloidosis	0.000	0.935	0.065
E85.3 Secondary systemic amyloidosis	0.000	0.935	0.065
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.935	0.065
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.935	0.065
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.935	0.065
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.935	0.065
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.936	0.063
I72.0 Aneurysm of carotid artery	0.000	0.937	0.063
I78.9 Disease of capillaries, unspecified	0.000	0.939	0.061
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.941	0.059
I78.8 Other diseases of capillaries	0.000	0.941	0.059
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.941	0.059
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.944	0.056
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.944	0.055
E85.9 Amyloidosis, unspecified	0.000	0.945	0.055
I02 Rheumatic chorea	0.000	0.945	0.055
I01 Rheumatic fever with heart involvement	0.000	0.945	0.055
I00 Rheumatic fever without mention of heart involvement	0.000	0.945	0.055
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.947	0.053
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.947	0.053
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.947	0.053
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.947	0.053
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.947	0.053
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.947	0.053
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.947	0.053
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.948	0.052
E80.5 Crigler-Najjar syndrome	0.000	0.948	0.052
E80.3 Defects of catalase and peroxydase	0.000	0.948	0.052
E80.2 Other porphyria	0.000	0.948	0.052
E80.1 Porphyria cutanea tarda	0.000	0.948	0.052
E80.0 Hereditary erythropoietic porphyria	0.000	0.948	0.052
E83.3 Disorders of phosphorus metabolism	0.000	0.951	0.049
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.952	0.046
I05-I09 Chronic rheumatic heart diseases	0.000	0.952	0.048
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.953	0.047
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.953	0.047
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.953	0.047
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.953	0.047
E89.5 Postprocedural testicular hypofunction	0.000	0.953	0.047
E89.4 Postprocedural ovarian failure	0.000	0.953	0.047
E89.2 Postprocedural hypoparathyroidism	0.000	0.953	0.047
E89.1 Postprocedural hypoinsulinaemia	0.000	0.953	0.047
E80.6 Other disorders of bilirubin metabolism	0.000	0.954	0.045
E89.3 Postprocedural hypopituitarism	0.000	0.954	0.046
I73 Other peripheral vascular diseases	0.000	0.957	0.043
I78.1 Naevus, nonneoplastic	0.000	0.958	0.042
I97.1 Other functional disturbances following cardiac surgery	0.000	0.959	0.041
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.960	0.040
I01.8 Other acute rheumatic heart disease	0.000	0.960	0.040
I01.2 Acute rheumatic myocarditis	0.000	0.960	0.040
I01.1 Acute rheumatic endocarditis	0.000	0.960	0.040
I01.0 Acute rheumatic pericarditis	0.000	0.960	0.040
I02.9 Rheumatic chorea without heart involvement	0.000	0.960	0.040
I02.0 Rheumatic chorea with heart involvement	0.000	0.960	0.040
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.963	0.037
E80.4 Gilbert's syndrome	0.000	0.963	0.037
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.964	0.036
I06 Rheumatic aortic valve diseases	0.000	0.966	0.034
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.966	0.034
I97.0 Postcardiotomy syndrome	0.000	0.966	0.034
I28 Other diseases of pulmonary vessels	0.001	0.966	0.033
I08 Multiple valve diseases	0.000	0.966	0.034
I09 Other rheumatic heart diseases	0.000	0.967	0.033
I99 Other and unspecified disorders of circulatory system	0.000	0.968	0.032
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.969	0.031
I73.8 Other specified peripheral vascular diseases	0.000	0.969	0.031
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.969	0.031
I08.8 Other multiple valve diseases	0.000	0.970	0.030
I10-I15 Hypertensive diseases	0.000	0.971	0.029
I27 Other pulmonary heart diseases	0.000	0.973	0.026
I08.0 Disorders of both mitral and aortic valves	0.000	0.974	0.026
I05 Rheumatic mitral valve diseases	0.000	0.975	0.025
I07 Rheumatic tricuspid valve diseases	0.000	0.975	0.025
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.975	0.025
I06.8 Other rheumatic aortic valve diseases	0.000	0.975	0.025
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.975	0.025
I06.1 Rheumatic aortic insufficiency	0.000	0.975	0.025
I06.0 Rheumatic aortic stenosis	0.000	0.975	0.025
I26 Pulmonary embolism	0.005	0.975	0.019
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.976	0.023
I28.1 Aneurysm of pulmonary artery	0.001	0.976	0.023
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.976	0.023
I08.9 Multiple valve disease, unspecified	0.000	0.976	0.024
I09.8 Other specified rheumatic heart diseases	0.000	0.976	0.024
I09.2 Chronic rheumatic pericarditis	0.000	0.976	0.024
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.976	0.024
I09.0 Rheumatic myocarditis	0.000	0.976	0.024
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.976	0.024
I28.8 Other specified diseases of pulmonary vessels	0.001	0.976	0.023
I09.9 Rheumatic heart disease, unspecified	0.000	0.977	0.023
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.977	0.023
I11 Hypertensive heart disease	0.000	0.977	0.023
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.977	0.022
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.977	0.022
I98.0 Cardiovascular syphilis	0.000	0.977	0.022
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.978	0.021
I13 Hypertensive heart and renal disease	0.000	0.979	0.021
I27.8 Other specified pulmonary heart diseases	0.000	0.980	0.020
E83.5 Disorders of calcium metabolism	0.000	0.980	0.020
I15 Secondary hypertension	0.000	0.980	0.020
I27.1 Kyphoscoliotic heart disease	0.001	0.981	0.019
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.981	0.019
I73.9 Peripheral vascular disease, unspecified	0.000	0.981	0.019
I05.1 Rheumatic mitral insufficiency	0.000	0.981	0.019
I05.2 Mitral stenosis with insufficiency	0.000	0.981	0.018
I05.8 Other mitral valve diseases	0.000	0.982	0.018
I07.9 Tricuspid valve disease, unspecified	0.000	0.982	0.018
I07.8 Other tricuspid valve diseases	0.000	0.982	0.018
I07.2 Tricuspid stenosis with insufficiency	0.000	0.982	0.018
I07.0 Tricuspid stenosis	0.000	0.982	0.018
I27.9 Pulmonary heart disease, unspecified	0.000	0.982	0.018
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.004	0.982	0.014
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.983	0.017
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.983	0.017
I27.0 Primary pulmonary hypertension	0.000	0.984	0.016
I27.2 Other secondary pulmonary hypertension	0.000	0.984	0.016
I15.1 Hypertension secondary to other renal disorders	0.000	0.984	0.016
E89.0 Postprocedural hypothyroidism	0.000	0.984	0.016
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.985	0.015
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.985	0.015
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.985	0.015
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.985	0.015
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.985	0.014
I05.9 Mitral valve disease, unspecified	0.000	0.986	0.014
I05.0 Mitral stenosis	0.000	0.986	0.014
I15.8 Other secondary hypertension	0.000	0.986	0.014
I15.2 Hypertension secondary to endocrine disorders	0.000	0.986	0.014
I15.0 Renovascular hypertension	0.000	0.986	0.014
H04 Disorders of lachrymal system	0.000	0.986	0.014
H04.2 Epiphora	0.000	0.986	0.014
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.987	0.013
R16.1 Splenomegaly, not elsewhere classified	0.012	0.988	0.000
H04.8 Other disorders of lachrymal system	0.000	0.989	0.011
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.989	0.011
I73.0 Raynaud's syndrome	0.000	0.989	0.011
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.989	0.011
I15.9 Seconday hypertension, unspecified	0.000	0.989	0.010
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.989	0.011
H04.9 Disorder of lachrymal system, unspecified	0.000	0.989	0.011
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.010	0.989	0.000
E87.5 Hyperkalaemia	0.000	0.990	0.010
H04.6 Other changes in lachrymal passages	0.000	0.990	0.010
H04.0 Dacryoadenitis	0.000	0.990	0.010
E87.3 Alkalosis	0.000	0.990	0.010
I12 Hypertensive renal disease	0.000	0.990	0.010
E87.4 Mixed disorder of acid-base balance	0.000	0.990	0.010
H04.4 Chronic inflammation of lachrymal passages	0.000	0.990	0.010
N39.4 Other specified urinary incontinence	0.000	0.991	0.009
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.991	0.009
I07.1 Tricuspid insufficiency	0.001	0.991	0.009
K08.3 Retained dental root	0.000	0.991	0.009
H04.1 Other disorders of lachrymal gland	0.000	0.992	0.008
E87.7 Fluid overload	0.000	0.992	0.008
E87.0 Hyperosmolality and hypernatraemia	0.000	0.992	0.008
I51.9 Heart disease, unspecified	0.000	0.992	0.008
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.993	0.006
K08 Other disorders of teeth and supporting structures	0.000	0.994	0.006
I12.9 Hypertensive renal disease without renal failure	0.000	0.994	0.005
I51 Complications and ill-defined descriptions of heart disease	0.000	0.994	0.006
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.994	0.006
I95 Hypotension	0.000	0.995	0.005
K91.4 Colostomy and enterostomy malfunction	0.000	0.995	0.005
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.995	0.005
I51.6 Cardiovascular disease, unspecified	0.000	0.995	0.005
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.005	0.995	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.995	0.005
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.995	0.005
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.995	0.005
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.995	0.005
E28.3 Primary ovarian failure	0.005	0.995	0.000
E40-E46 Malnutrition	0.000	0.995	0.004
I51.0 Cardiac septal defect, acquired	0.000	0.996	0.004
N36.2 Urethral caruncle	0.004	0.996	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.996	0.004
E28 Ovarian dysfunction	0.004	0.996	0.000
W19.4 Street and highway	0.004	0.996	0.000
I51.5 Myocardial degeneration	0.000	0.996	0.004
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.996	0.004
N36.8 Other specified disorders of urethra	0.004	0.996	0.000
I51.4 Myocarditis, unspecified	0.000	0.996	0.004
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
I95.8 Other hypotension	0.000	0.996	0.004
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.004	0.996	0.000
I51.7 Cardiomegaly	0.000	0.996	0.004
E61.1 Iron deficiency	0.000	0.996	0.004
I30-I52 Other forms of heart disease	0.000	0.996	0.004
E11.2 With renal complications	0.000	0.996	0.004
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.996	0.004
E11 Non-insulin-dependent diabetes mellitus	0.000	0.996	0.004
E50-E64 Other nutritional deficiencies	0.000	0.996	0.004
E46 Unspecified protein-energy malnutrition	0.000	0.996	0.004
E61 Deficiency of other nutrient elements	0.000	0.996	0.004
H52.1 Myopia	0.004	0.996	0.000
E11.1 With ketoacidosis	0.000	0.996	0.004
I95.0 Idiopathic hypotension	0.000	0.996	0.003
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.996	0.004
E23.2 Diabetes insipidus	0.004	0.996	0.000
E11.0 With coma	0.000	0.996	0.004
E87.6 Hypokalaemia	0.000	0.996	0.004
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.996	0.003
E45 Retarded development following protein-energy malnutrition	0.000	0.996	0.003
E43 Unspecified severe protein-energy malnutrition	0.000	0.996	0.003
E42 Marasmic kwashiorkor	0.000	0.996	0.003
E41 Nutritional marasmus	0.000	0.996	0.003
E40 Kwashiorkor	0.000	0.996	0.003
E20-E35 Disorders of other endocrine glands	0.003	0.996	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.996	0.003
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.996	0.003
N36 Other disorders of urethra	0.003	0.997	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.997	0.003
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.003
T40.2 Other opioids	0.000	0.997	0.003
R16.0 Hepatomegaly, not elsewhere classified	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
I35.0 Aortic (valve) stenosis	0.000	0.997	0.003
E15 Nondiabetic hypoglycaemic coma	0.000	0.997	0.003
E10-E14 Diabetes mellitus	0.000	0.997	0.003
K91.3 Postoperative intestinal obstruction	0.000	0.997	0.003
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.003
E11.5 With peripheral circulatory complications	0.000	0.997	0.003
E11.8 With unspecified complications	0.000	0.997	0.003
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
I35 Nonrheumatic aortic valve disorders	0.000	0.997	0.003
H02.0 Entropion and trichiasis of eyelid	0.003	0.997	0.000
I52 Other heart disorders in diseases classified elsewhere	0.000	0.997	0.003
I48 Atrial fibrillation and flutter	0.000	0.997	0.003
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.997	0.003
I41 Myocarditis in diseases classified elsewhere	0.000	0.997	0.003
I40 Acute myocarditis	0.000	0.997	0.003
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.997	0.003
I32 Pericarditis in diseases classified elsewhere	0.000	0.997	0.003
W19 Unspecified fall	0.003	0.997	0.000
W19.1 Residential institution	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.003	0.997	0.000
E11.6 With other specified complications	0.000	0.997	0.003
E11.7 With multiple complications	0.000	0.997	0.003
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.997	0.003
E63 Other nutritional deficiencies	0.000	0.997	0.003
E56 Other vitamin deficiencies	0.000	0.997	0.003
E51 Thiamine deficiency	0.000	0.997	0.003
E50 Vitamin A deficiency	0.000	0.997	0.003
E60 Dietary zinc deficiency	0.000	0.997	0.003
E59 Dietary selenium deficiency	0.000	0.997	0.003
E58 Dietary calcium deficiency	0.000	0.997	0.003
E54 Ascorbic acid deficiency	0.000	0.997	0.003
E52 Niacin deficiency [pellagra]	0.000	0.997	0.003
I37 Pulmonary valve disorders	0.000	0.997	0.003
E16.2 Hypoglycaemia, unspecified	0.000	0.997	0.003
C15.5 Lower third of oesophagus	0.000	0.997	0.003
E61.9 Deficiency of nutrient element, unspecified	0.000	0.997	0.003
E61.8 Deficiency of other specified nutrient elements	0.000	0.997	0.003
E61.7 Deficiency of multiple nutrient elements	0.000	0.997	0.003
E61.6 Vanadium deficiency	0.000	0.997	0.003
E61.5 Molybdenum deficiency	0.000	0.997	0.003
E61.4 Chromium deficiency	0.000	0.997	0.003
E61.3 Manganese deficiency	0.000	0.997	0.003
E61.0 Copper deficiency	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.003	0.997	0.000
W19.9 Unspecified place	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.003	0.997	0.000
I46 Cardiac arrest	0.000	0.997	0.003
E11.4 With neurological complications	0.000	0.997	0.003
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.997	0.003
K91.5 Postcholecystectomy syndrome	0.000	0.997	0.003
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
I33 Acute and subacute endocarditis	0.000	0.997	0.003
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.997	0.003
I36 Nonrheumatic tricuspid valve disorders	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.997	0.003
N36.9 Urethral disorder, unspecified	0.003	0.997	0.000
I38 Endocarditis, valve unspecified	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
T40.4 Other synthetic narcotics	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.997	0.003
E44.0 Moderate protein-energy malnutrition	0.000	0.997	0.003
E61.2 Magnesium deficiency	0.000	0.997	0.003
N36.1 Urethral diverticulum	0.003	0.997	0.000
E29 Testicular dysfunction	0.003	0.997	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.997	0.003
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.997	0.003
E16.4 Abnormal secretion of gastrin	0.000	0.997	0.003
E16.3 Increased secretion of glucagon	0.000	0.997	0.003
E16.1 Other hypoglycaemia	0.000	0.997	0.003
H52 Disorders of refraction and accommodation	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
E65 Localised adiposity	0.000	0.997	0.003
H52.2 Astigmatism	0.003	0.997	0.000
N36.0 Urethral fistula	0.003	0.997	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.997	0.003
E26 Hyperaldosteronism	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.003	0.997	0.000
W19.6 Industrial and construction area	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations