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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116424300
log Bayes Factor = 20.3133
Chromosome 8   position 143,412,988  (GRCh37) Explore rs116424300 on Ensembl!
Variant rs116424300 is part of Cluster X0213

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
S80-S89 Injuries to the knee and lower leg
0.994 0.006 0.000
I50 Heart failure
0.992 0.008 0.000
I51 Complications and ill-defined descriptions of heart disease
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
Chapter II Neoplasms
0.990 0.010 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.989 0.011 0.000
D50-D53 Nutritional anaemias
0.985 0.015 0.000
D10-D36 Benign neoplasms
0.983 0.017 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.980 0.020 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.978 0.022 0.000
D50 Iron deficiency anaemia
0.976 0.024 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.973 0.027 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.972 0.028 0.000
K55-K64 Other diseases of intestines
0.971 0.029 0.000
I44 Atrioventricular and left bundle-branch block
0.970 0.030 0.000
D50.9 Iron deficiency anaemia, unspecified
0.968 0.032 0.000
R79 Other abnormal findings of blood chemistry
0.967 0.033 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.967 0.033 0.000
R30-R39 Symptoms and signs involving the urinary system
0.965 0.035 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.965 0.035 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.961 0.039 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.960 0.040 0.000
S80 Superficial injury of lower leg
0.958 0.042 0.000
M70-M79 Other soft tissue disorders
0.954 0.046 0.000
Chapter VI Diseases of the nervous system
0.954 0.046 0.000
D12.2 Ascending colon
0.953 0.047 0.000
I51.9 Heart disease, unspecified
0.953 0.047 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.948 0.052 0.000
I26 Pulmonary embolism
0.948 0.052 0.000
R13 Dysphagia
0.947 0.053 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.947 0.053 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.945 0.055 0.000
F10.0 Acute intoxication
0.943 0.057 0.000
K20 Oesophagitis
0.942 0.058 0.000
K58 Irritable bowel syndrome
0.941 0.059 0.000
M45-M49 Spondylopathies
0.940 0.060 0.000
R39 Other symptoms and signs involving the urinary system
0.935 0.065 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.935 0.065 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.933 0.067 0.000
F10.1 Harmful use
0.932 0.068 0.000
K21 Gastro-oesophageal reflux disease
0.928 0.072 0.000
K90-K93 Other diseases of the digestive system
0.928 0.072 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.924 0.076 0.000
I50.0 Congestive heart failure
0.924 0.076 0.000
I44.7 Left bundle-branch block, unspecified
0.921 0.079 0.000
M80-M85 Disorders of bone density and structure
0.920 0.080 0.000
S81 Open wound of lower leg
0.913 0.087 0.000
S80.9 Superficial injury of lower leg, unspecified
0.912 0.088 0.000
I50.1 Left ventricular failure
0.910 0.090 0.000
I49 Other cardiac arrhythmias
0.910 0.090 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.910 0.090 0.000
R25 Abnormal involuntary movements
0.906 0.094 0.000
I50.9 Heart failure, unspecified
0.905 0.095 0.000
S00-S09 Injuries to the head
0.904 0.096 0.000
M47 Spondylosis
0.901 0.099 0.000
I47 Paroxysmal tachycardia
0.898 0.102 0.000
R35 Polyuria
0.898 0.102 0.000
S60-S69 Injuries to the wrist and hand
0.898 0.102 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.893 0.107 0.000
K26 Duodenal ulcer
0.893 0.107 0.000
K56.2 Volvulus
0.890 0.110 0.000
Chapter I Certain infectious and parasitic diseases
0.889 0.111 0.000
I34 Nonrheumatic mitral valve disorders
0.886 0.114 0.000
R06 Abnormalities of breathing
0.885 0.115 0.000
M47.9 Spondylosis, unspecified
0.881 0.119 0.000
R39.1 Other difficulties with micturition
0.879 0.121 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.878 0.122 0.000
D12.8 Rectum
0.877 0.123 0.000
D27 Benign neoplasm of ovary
0.877 0.123 0.000
I51.7 Cardiomegaly
0.876 0.124 0.000
I51.8 Other ill-defined heart diseases
0.873 0.127 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.870 0.130 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.869 0.131 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.864 0.136 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.862 0.138 0.000
S20-S29 Injuries to the thorax
0.862 0.138 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.862 0.138 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.860 0.140 0.000
K92 Other diseases of digestive system
0.860 0.140 0.000
R06.0 Dyspnoea
0.856 0.144 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.855 0.145 0.000
Chapter VIII Diseases of the ear and mastoid process
0.854 0.146 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.852 0.148 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.850 0.150 0.000
R14 Flatulence and related conditions
0.847 0.153 0.000
I44.6 Other and unspecified fascicular block
0.844 0.156 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.844 0.156 0.000
A00-A09 Intestinal infectious diseases
0.844 0.156 0.000
K12 Stomatitis and related lesions
0.843 0.157 0.000
G20-G26 Extrapyramidal and movement disorders
0.840 0.160 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.839 0.161 0.000
D12.9 Anus and anal canal
0.837 0.163 0.000
R02 Gangrene, not elsewhere classified
0.836 0.164 0.000
D12.6 Colon, unspecified
0.835 0.165 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.834 0.166 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.833 0.167 0.000
S81.8 Open wound of other parts of lower leg
0.833 0.167 0.000
L40-L45 Papulosquamous disorders
0.831 0.169 0.000
E10-E14 Diabetes mellitus
0.831 0.169 0.000
A04 Other bacterial intestinal infections
0.829 0.171 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.829 0.171 0.000
M81 Osteoporosis without pathological fracture
0.828 0.172 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.828 0.172 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.826 0.174 0.000
K08 Other disorders of teeth and supporting structures
0.824 0.176 0.000
S06 Intracranial injury
0.823 0.177 0.000
M50-M54 Other dorsopathies
0.823 0.177 0.000
Chapter XX External causes of morbidity and mortality
0.822 0.178 0.000
D17 Benign lipomatous neoplasm
0.822 0.178 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.819 0.181 0.000
Chapter X Diseases of the respiratory system
0.816 0.184 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.816 0.184 0.000
I34.0 Mitral (valve) insufficiency
0.815 0.185 0.000
R25.1 Tremor, unspecified
0.813 0.187 0.000
S70-S79 Injuries to the hip and thigh
0.812 0.188 0.000
A04.8 Other specified bacterial intestinal infections
0.809 0.191 0.000
C78.7 Secondary malignant neoplasm of liver
0.809 0.191 0.000
C80 Malignant neoplasm without specification of site
0.806 0.194 0.000
G56 Mononeuropathies of upper limb
0.805 0.195 0.000
D12.0 Caecum
0.804 0.196 0.000
R25.2 Cramp and spasm
0.803 0.197 0.000
K56.7 Ileus, unspecified
0.800 0.200 0.000
C64-C68 Malignant neoplasms of urinary tract
0.799 0.201 0.000
K25 Gastric ulcer
0.798 0.202 0.000
K55 Vascular disorders of intestine
0.798 0.202 0.000
I80 Phlebitis and thrombophlebitis
0.795 0.205 0.000
S50-S59 Injuries to the elbow and forearm
0.794 0.206 0.000
D25 Leiomyoma of uterus
0.794 0.206 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.793 0.207 0.000
M84 Disorders of continuity of bone
0.792 0.208 0.000
S82 Fracture of lower leg, including ankle
0.790 0.210 0.000
R71 Abnormality of red blood cells
0.790 0.210 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.790 0.210 0.000
K05 Gingivitis and periodontal diseases
0.789 0.211 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.788 0.212 0.000
L40 Psoriasis
0.788 0.212 0.000
F10.2 Dependence syndrome
0.788 0.212 0.000
M77 Other enthesopathies
0.787 0.213 0.000
D70 Agranulocytosis
0.786 0.214 0.000
D60-D64 Aplastic and other anaemias
0.786 0.214 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.785 0.215 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.784 0.216 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.783 0.217 0.000
D23 Other benign neoplasms of skin
0.782 0.218 0.000
K90 Intestinal malabsorption
0.781 0.219 0.000
D30 Benign neoplasm of urinary organs
0.780 0.219 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.780 0.220 0.000
G56.2 Lesion of ulnar nerve
0.780 0.220 0.000
E14 Unspecified diabetes mellitus
0.779 0.221 0.000
R07 Pain in throat and chest
0.779 0.221 0.000
R27 Other lack of coordination
0.778 0.222 0.000
C51-C58 Malignant neoplasms of female genital organs
0.778 0.222 0.000
K02 Dental caries
0.777 0.223 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.775 0.225 0.000
I47.2 Ventricular tachycardia
0.775 0.225 0.000
I31 Other diseases of pericardium
0.775 0.225 0.000
I49.9 Cardiac arrhythmia, unspecified
0.773 0.227 0.000
K10 Other diseases of jaws
0.767 0.233 0.000
D51 Vitamin B12 deficiency anaemia
0.766 0.234 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.764 0.236 0.000
M86-M90 Other osteopathies
0.764 0.236 0.000
M81.9 Osteoporosis, unspecified
0.763 0.237 0.000
R04 Haemorrhage from respiratory passages
0.763 0.237 0.000
M54 Dorsalgia
0.762 0.238 0.000
I49.3 Ventricular premature depolarisation
0.761 0.239 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.760 0.240 0.000
S62 Fracture at wrist and hand level
0.760 0.240 0.000
K07 Dentofacial anomalies [including malocclusion]
0.760 0.240 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.760 0.240 0.000
I44.2 Atrioventricular block, complete
0.760 0.240 0.000
I44.3 Other and unspecified atrioventricular block
0.759 0.241 0.000
S80.0 Contusion of knee
0.758 0.242 0.000
M46 Other inflammatory spondylopathies
0.757 0.243 0.000
K70-K77 Diseases of liver
0.757 0.243 0.000
S60 Superficial injury of wrist and hand
0.753 0.247 0.000
M75 Shoulder lesions
0.752 0.248 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.752 0.248 0.000
R74 Abnormal serum enzyme levels
0.751 0.249 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.751 0.249 0.000
I42 Cardiomyopathy
0.750 0.250 0.000
M65-M68 Disorders of synovium and tendon
0.750 0.250 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.749 0.251 0.000
S68 Traumatic amputation of wrist and hand
0.748 0.252 0.000
F30-F39 Mood [affective] disorders
0.748 0.252 0.000
S80.8 Other superficial injuries of lower leg
0.748 0.252 0.000
K04 Diseases of pulp and periapical tissues
0.747 0.253 0.000
R01 Cardiac murmurs and other cardiac sounds
0.747 0.253 0.000
M71 Other bursopathies
0.746 0.254 0.000
F10.4 Withdrawal state with delirium
0.746 0.254 0.000
K27 Peptic ulcer, site unspecified
0.746 0.254 0.000
K56.6 Other and unspecified intestinal obstruction
0.742 0.258 0.000
D52 Folate deficiency anaemia
0.742 0.258 0.000
I47.0 Reentry ventricular arrhythmia
0.742 0.258 0.000
R34 Anuria and oliguria
0.739 0.261 0.000
G40-G47 Episodic and paroxysmal disorders
0.739 0.261 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.738 0.262 0.000
E70-E90 Metabolic disorders
0.738 0.262 0.000
S81.9 Open wound of lower leg, part unspecified
0.738 0.262 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.737 0.263 0.000
J00-J06 Acute upper respiratory infections
0.737 0.263 0.000
F99-F99 Unspecified mental disorder
0.735 0.265 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.734 0.266 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.734 0.266 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
C45 Mesothelioma
0.733 0.267 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.733 0.267 0.000
K09 Cysts of oral region, not elsewhere classified
0.732 0.267 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.732 0.268 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.731 0.269 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.731 0.269 0.000
S00 Superficial injury of head
0.730 0.270 0.000
R23 Other skin changes
0.730 0.270 0.000
O80-O84 Delivery
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.729 0.271 0.000
R15 Faecal incontinence
0.729 0.271 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.728 0.272 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.727 0.273 0.000
I35 Nonrheumatic aortic valve disorders
0.727 0.273 0.000
D10 Benign neoplasm of mouth and pharynx
0.727 0.273 0.000
G25 Other extrapyramidal and movement disorders
0.726 0.274 0.000
S90-S99 Injuries to the ankle and foot
0.726 0.274 0.000
K12.2 Cellulitis and abscess of mouth
0.725 0.275 0.000
K31 Other diseases of stomach and duodenum
0.724 0.276 0.000
J20-J22 Other acute lower respiratory infections
0.723 0.277 0.000
T91 Sequelae of injuries of neck and trunk
0.722 0.278 0.000
K60 Fissure and fistula of anal and rectal regions
0.722 0.278 0.000
S27 Injury of other and unspecified intrathoracic organs
0.720 0.279 0.000
I05-I09 Chronic rheumatic heart diseases
0.720 0.280 0.000
F80-F89 Disorders of psychological development
0.719 0.281 0.000
K00 Disorders of tooth development and eruption
0.719 0.281 0.000
E14.9 Without complications
0.718 0.282 0.000
A30-A49 Other bacterial diseases
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I44.1 Atrioventricular block, second degree
0.717 0.283 0.000
S06.2 Diffuse brain injury
0.717 0.283 0.000
I30 Acute pericarditis
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.286 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
S88 Traumatic amputation of lower leg
0.712 0.288 0.000
S87 Crushing injury of lower leg
0.712 0.288 0.000
S86 Injury of muscle and tendon at lower leg level
0.712 0.288 0.000
S85 Injury of blood vessels at lower leg level
0.712 0.288 0.000
S84 Injury of nerves at lower leg level
0.712 0.288 0.000
D25.0 Submucous leiomyoma of uterus
0.712 0.288 0.000
R09.1 Pleurisy
0.711 0.289 0.000
K83 Other diseases of biliary tract
0.711 0.289 0.000
K35-K38 Diseases of appendix
0.711 0.289 0.000
M54.3 Sciatica
0.711 0.289 0.000
I51.6 Cardiovascular disease, unspecified
0.710 0.290 0.000
I51.5 Myocardial degeneration
0.710 0.290 0.000
I51.4 Myocarditis, unspecified
0.710 0.290 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.710 0.290 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.710 0.290 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.710 0.290 0.000
I51.0 Cardiac septal defect, acquired
0.710 0.290 0.000
M79.6 Pain in limb
0.710 0.290 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
F60-F69 Disorders of adult personality and behaviour
0.710 0.290 0.000
I49.1 Atrial premature depolarisation
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
I87 Other disorders of veins
0.710 0.290 0.000
M91-M94 Chondropathies
0.709 0.290 0.000
S82.0 Fracture of patella
0.709 0.291 0.000
K28 Gastrojejunal ulcer
0.709 0.291 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.709 0.291 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.708 0.292 0.000
I49.4 Other and unspecified premature depolarisation
0.708 0.292 0.000
D53 Other nutritional anaemias
0.706 0.293 0.000
T92 Sequelae of injuries of upper limb
0.706 0.294 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.705 0.295 0.000
D31 Benign neoplasm of eye and adnexa
0.705 0.295 0.000
D29 Benign neoplasm of male genital organs
0.705 0.295 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.705 0.295 0.000
D26 Other benign neoplasms of uterus
0.705 0.295 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.705 0.295 0.000
D19 Benign neoplasm of mesothelial tissue
0.705 0.295 0.000
D16 Benign neoplasm of bone and articular cartilage
0.705 0.295 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.705 0.295 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.705 0.295 0.000
L40.5 Arthropathic psoriasis
0.705 0.295 0.000
E20-E35 Disorders of other endocrine glands
0.704 0.296 0.000
S89 Other and unspecified injuries of lower leg
0.704 0.296 0.000
H90-H95 Other disorders of ear
0.703 0.297 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.703 0.297 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.702 0.298 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.702 0.298 0.000
R77 Other abnormalities of plasma proteins
0.702 0.298 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.702 0.298 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.702 0.298 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.701 0.299 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.701 0.299 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.701 0.299 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.701 0.299 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.701 0.299 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.701 0.299 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.701 0.299 0.000
F11 Mental and behavioural disorders due to use of opioids
0.701 0.299 0.000
K26.7 Chronic without haemorrhage or perforation
0.701 0.299 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.701 0.299 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.700 0.300 0.000
D50.1 Sideropenic dysphagia
0.700 0.300 0.000
M72 Fibroblastic disorders
0.700 0.300 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.700 0.300 0.000
K12.1 Other forms of stomatitis
0.699 0.301 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.698 0.302 0.000
F10.9 Unspecified mental and behavioural disorder
0.698 0.302 0.000
F10.8 Other mental and behavioural disorders
0.698 0.302 0.000
F10.7 Residual and late-onset psychotic disorder
0.698 0.302 0.000
F10.6 Amnesic syndrome
0.698 0.302 0.000
F10.5 Psychotic disorder
0.698 0.302 0.000
D12.1 Appendix
0.697 0.303 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.696 0.304 0.000
D25.2 Subserosal leiomyoma of uterus
0.696 0.304 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.696 0.304 0.000
I49.5 Sick sinus syndrome
0.696 0.304 0.000
I44.5 Left posterior fascicular block
0.695 0.305 0.000
I44.4 Left anterior fascicular block
0.695 0.305 0.000
D50.8 Other iron deficiency anaemias
0.694 0.306 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.694 0.306 0.000
R79.0 Abnormal level of blood mineral
0.693 0.306 0.000
K83.8 Other specified diseases of biliary tract
0.693 0.307 0.000
O00-O08 Pregnancy with abortive outcome
0.693 0.307 0.000
R36 Urethral discharge
0.692 0.308 0.000
I28 Other diseases of pulmonary vessels
0.692 0.308 0.000
T66-T78 Other and unspecified effects of external causes
0.692 0.308 0.000
K56.1 Intussusception
0.691 0.308 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.691 0.308 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.691 0.309 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.691 0.309 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.309 0.000
H65-H75 Diseases of middle ear and mastoid
0.691 0.309 0.000
F20 Schizophrenia
0.690 0.310 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.689 0.311 0.000
I33 Acute and subacute endocarditis
0.689 0.311 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.688 0.311 0.000
K03 Other diseases of hard tissues of teeth
0.688 0.311 0.000
D34 Benign neoplasm of thyroid gland
0.688 0.312 0.000
D23.1 Skin of eyelid, including canthus
0.687 0.313 0.000
A04.5 Campylobacter enteritis
0.687 0.313 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.687 0.313 0.000
L40.9 Psoriasis, unspecified
0.687 0.313 0.000
S80.7 Multiple superficial injuries of lower leg
0.686 0.313 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.686 0.313 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.686 0.314 0.000
K14 Diseases of tongue
0.684 0.316 0.000
T93 Sequelae of injuries of lower limb
0.684 0.316 0.000
M76 Enthesopathies of lower limb, excluding foot
0.684 0.316 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.684 0.316 0.000
G70-G73 Diseases of myoneural junction and muscle
0.684 0.316 0.000
R26 Abnormalities of gait and mobility
0.683 0.317 0.000
S62.6 Fracture of other finger
0.683 0.317 0.000
K22 Other diseases of oesophagus
0.683 0.317 0.000
C56 Malignant neoplasm of ovary
0.682 0.318 0.000
R06.5 Mouth breathing
0.682 0.318 0.000
L50-L54 Urticaria and erythema
0.682 0.318 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.681 0.319 0.000
I49.8 Other specified cardiac arrhythmias
0.680 0.320 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.679 0.321 0.000
M79.7 Fibromyalgia
0.679 0.321 0.000
R47-R49 Symptoms and signs involving speech and voice
0.679 0.321 0.000
F23 Acute and transient psychotic disorders
0.679 0.321 0.000
K25.7 Chronic without haemorrhage or perforation
0.678 0.322 0.000
K56.3 Gallstone ileus
0.678 0.322 0.000
K56.0 Paralytic ileus
0.678 0.322 0.000
S01 Open wound of head
0.678 0.322 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
R03.1 Nonspecific low blood-pressure reading
0.677 0.323 0.000
K92.0 Haematemesis
0.676 0.324 0.000
C80.9 Malignant neoplasm, unspecified
0.676 0.324 0.000
S06.5 Traumatic subdural haemorrhage
0.676 0.324 0.000
K90.0 Coeliac disease
0.675 0.325 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.675 0.325 0.000
M75.4 Impingement syndrome of shoulder
0.674 0.326 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.674 0.326 0.000
M49 Spondylopathies in diseases classified elsewhere
0.674 0.326 0.000
K02.8 Other dental caries
0.673 0.327 0.000
M79.2 Neuralgia and neuritis, unspecified
0.673 0.327 0.000
R76 Other abnormal immunological findings in serum
0.673 0.327 0.000
G24 Dystonia
0.673 0.327 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.672 0.328 0.000
K92.1 Melaena
0.671 0.329 0.000
R39.2 Extrarenal uraemia
0.671 0.329 0.000
R39.0 Extravasation of urine
0.671 0.329 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.671 0.329 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.670 0.330 0.000
E89.0 Postprocedural hypothyroidism
0.670 0.330 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.670 0.330 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.670 0.330 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.669 0.331 0.000
I86 Varicose veins of other sites
0.669 0.331 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.669 0.331 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.668 0.332 0.000
D24 Benign neoplasm of breast
0.668 0.332 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.668 0.332 0.000
B15-B19 Viral hepatitis
0.667 0.333 0.000
Q50-Q56 Congenital malformations of genital organs
0.667 0.333 0.000
K05.3 Chronic periodontitis
0.666 0.333 0.000
C79 Secondary malignant neoplasm of other sites
0.666 0.334 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.665 0.334 0.000
D80-D89 Certain disorders involving the immune mechanism
0.665 0.335 0.000
M79.8 Other specified soft tissue disorders
0.665 0.335 0.000
F22 Persistent delusional disorders
0.665 0.335 0.000
M40-M43 Deforming dorsopathies
0.664 0.336 0.000
S40-S49 Injuries to the shoulder and upper arm
0.663 0.336 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.663 0.337 0.000
D61 Other aplastic anaemias
0.663 0.337 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.663 0.337 0.000
C15-C26 Malignant neoplasms of digestive organs
0.662 0.338 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.661 0.339 0.000
D32 Benign neoplasm of meninges
0.661 0.339 0.000
M83 Adult osteomalacia
0.659 0.341 0.000
M82 Osteoporosis in diseases classified elsewhere
0.659 0.341 0.000
T17 Foreign body in respiratory tract
0.659 0.341 0.000
C78.0 Secondary malignant neoplasm of lung
0.659 0.341 0.000
M47.2 Other spondylosis with radiculopathy
0.658 0.342 0.000
M85 Other disorders of bone density and structure
0.657 0.343 0.000
S81.7 Multiple open wounds of lower leg
0.655 0.345 0.000
I47.1 Supraventricular tachycardia
0.655 0.345 0.000
S09 Other and unspecified injuries of head
0.655 0.345 0.000
G50 Disorders of trigeminal nerve
0.654 0.346 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.654 0.346 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.653 0.347 0.000
I49.2 Junctional premature depolarisation
0.652 0.347 0.000
L10-L14 Bullous disorders
0.652 0.348 0.000
D11 Benign neoplasm of major salivary glands
0.652 0.348 0.000
J95-J99 Other diseases of the respiratory system
0.652 0.348 0.000
R07.1 Chest pain on breathing
0.651 0.348 0.000
S82.00 Fracture of patella (closed)
0.651 0.349 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.651 0.349 0.000
R12 Heartburn
0.650 0.350 0.000
R25.3 Fasciculation
0.650 0.350 0.000
R25.0 Abnormal head movements
0.650 0.350 0.000
F32 Depressive episode
0.650 0.350 0.000
G51 Facial nerve disorders
0.649 0.351 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.649 0.351 0.000
J22 Unspecified acute lower respiratory infection
0.648 0.352 0.000
S08 Traumatic amputation of part of head
0.648 0.352 0.000
S07 Crushing injury of head
0.648 0.352 0.000
S05 Injury of eye and orbit
0.648 0.352 0.000
S04 Injury of cranial nerves
0.648 0.352 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.648 0.352 0.000
K55.2 Angiodysplasia of colon
0.647 0.353 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.647 0.353 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.646 0.354 0.000
M47.1 Other spondylosis with myelopathy
0.646 0.354 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.646 0.354 0.000
G47 Sleep disorders
0.646 0.354 0.000
J03 Acute tonsillitis
0.645 0.355 0.000
W20-W49 Exposure to inanimate mechanical forces
0.645 0.355 0.000
F29 Unspecified nonorganic psychosis
0.645 0.355 0.000
J60-J70 Lung diseases due to external agents
0.644 0.356 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.644 0.356 0.000
S69 Other and unspecified injuries of wrist and hand
0.644 0.356 0.000
S67 Crushing injury of wrist and hand
0.644 0.356 0.000
S65 Injury of blood vessels at wrist and hand level
0.644 0.356 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.644 0.356 0.000
M45 Ankylosing spondylitis
0.643 0.356 0.000
L20-L30 Dermatitis and eczema
0.643 0.356 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.643 0.357 0.000
E14.3 With ophthalmic complications
0.642 0.358 0.000
R04.2 Haemoptysis
0.642 0.358 0.000
E11 Non-insulin-dependent diabetes mellitus
0.642 0.358 0.000
M05-M14 Inflammatory polyarthropathies
0.641 0.359 0.000
S81.0 Open wound of knee
0.641 0.359 0.000
E40-E46 Malnutrition
0.641 0.359 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.641 0.359 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.640 0.360 0.000
K26.5 Chronic or unspecified with perforation
0.640 0.360 0.000
K26.2 Acute with both haemorrhage and perforation
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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