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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16876083
log Bayes Factor = 1.85429
Chromosome 8   position 29,716,261  (GRCh37) Explore rs16876083 on Ensembl!
Variant rs16876083 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.985 0.015 0.000
Chapter IX Diseases of the circulatory system
0.981 0.019 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.973 0.027 0.000
I84 Haemorrhoids
0.969 0.031 0.000
I84.9 Unspecified haemorrhoids without complication
0.960 0.040 0.000
Chapter II Neoplasms
0.942 0.058 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.935 0.065 0.000
R50-R69 General symptoms and signs
0.930 0.070 0.000
R55 Syncope and collapse
0.909 0.091 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.906 0.094 0.000
Chapter VI Diseases of the nervous system
0.896 0.104 0.000
I84.2 Internal haemorrhoids without complication
0.887 0.113 0.000
I60-I69 Cerebrovascular diseases
0.879 0.121 0.000
D10-D36 Benign neoplasms
0.877 0.123 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.856 0.144 0.000
Chapter XI Diseases of the digestive system
0.855 0.145 0.000
I84.6 Residual haemorrhoidal skin tags
0.845 0.155 0.000
M45-M49 Spondylopathies
0.836 0.163 0.000
R51 Headache
0.831 0.169 0.000
I30-I52 Other forms of heart disease
0.817 0.183 0.000
Chapter VIII Diseases of the ear and mastoid process
0.815 0.185 0.000
D17 Benign lipomatous neoplasm
0.812 0.188 0.000
C15-C26 Malignant neoplasms of digestive organs
0.803 0.197 0.000
R53 Malaise and fatigue
0.797 0.203 0.000
C51-C58 Malignant neoplasms of female genital organs
0.797 0.203 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.788 0.212 0.000
Chapter V Mental and behavioural disorders
0.782 0.218 0.000
R50 Fever of unknown origin
0.776 0.224 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.767 0.233 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.761 0.239 0.000
Chapter XIV Diseases of the genitourinary system
0.758 0.242 0.000
M48 Other spondylopathies
0.755 0.245 0.000
M05-M14 Inflammatory polyarthropathies
0.752 0.248 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.751 0.249 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.750 0.250 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.750 0.250 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.745 0.255 0.000
D25 Leiomyoma of uterus
0.744 0.256 0.000
Chapter XXI Factors influencing health status and contact with health services
0.743 0.257 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.741 0.259 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.738 0.262 0.000
I63 Cerebral infarction
0.736 0.264 0.000
I67 Other cerebrovascular diseases
0.734 0.266 0.000
K70-K77 Diseases of liver
0.724 0.276 0.000
N40-N51 Diseases of male genital organs
0.724 0.276 0.000
R47-R49 Symptoms and signs involving speech and voice
0.723 0.277 0.000
I05-I09 Chronic rheumatic heart diseases
0.717 0.283 0.000
Chapter XX External causes of morbidity and mortality
0.716 0.284 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.716 0.284 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.707 0.293 0.000
Chapter XXII Codes for special purposes
0.706 0.294 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.706 0.294 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.706 0.294 0.000
I00-I02 Acute rheumatic fever
0.703 0.297 0.000
Chapter VII Diseases of the eye and adnexa
0.700 0.300 0.000
D22 Melanocytic naevi
0.700 0.300 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.698 0.302 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.698 0.302 0.000
I88 Nonspecific lymphadenitis
0.698 0.302 0.000
I87 Other disorders of veins
0.698 0.302 0.000
I86 Varicose veins of other sites
0.698 0.302 0.000
I85 Oesophageal varices
0.698 0.302 0.000
I82 Other venous embolism and thrombosis
0.698 0.302 0.000
I81 Portal vein thrombosis
0.698 0.302 0.000
M48.0 Spinal stenosis
0.697 0.303 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.695 0.305 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.695 0.305 0.000
I84.5 External haemorrhoids without complication
0.695 0.305 0.000
I84.4 External haemorrhoids with other complications
0.695 0.305 0.000
I84.3 External thrombosed haemorrhoids
0.695 0.305 0.000
I84.0 Internal thrombosed haemorrhoids
0.695 0.305 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.693 0.307 0.000
M47 Spondylosis
0.692 0.307 0.000
M40-M43 Deforming dorsopathies
0.691 0.309 0.000
R52 Pain, not elsewhere classified
0.687 0.313 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.686 0.314 0.000
H65-H75 Diseases of middle ear and mastoid
0.685 0.315 0.000
K50-K52 Noninfective enteritis and colitis
0.685 0.315 0.000
G90-G99 Other disorders of the nervous system
0.684 0.316 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.684 0.316 0.000
C18 Malignant neoplasm of colon
0.683 0.316 0.000
R59 Enlarged lymph nodes
0.682 0.318 0.000
D23 Other benign neoplasms of skin
0.681 0.319 0.000
I46 Cardiac arrest
0.679 0.321 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.676 0.324 0.000
D00-D09 In situ neoplasms
0.676 0.324 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.676 0.324 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.676 0.324 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.676 0.324 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.676 0.324 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.676 0.324 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.676 0.324 0.000
M15-M19 Arthrosis
0.675 0.325 0.000
G40-G47 Episodic and paroxysmal disorders
0.672 0.328 0.000
I34 Nonrheumatic mitral valve disorders
0.672 0.328 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.670 0.329 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.670 0.329 0.000
I49 Other cardiac arrhythmias
0.670 0.330 0.000
K65-K67 Diseases of peritoneum
0.669 0.331 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.668 0.332 0.000
G56 Mononeuropathies of upper limb
0.668 0.332 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.667 0.333 0.000
R68 Other general symptoms and signs
0.667 0.333 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.667 0.333 0.000
R62 Lack of expected normal physiological development
0.667 0.333 0.000
R61 Hyperhidrosis
0.667 0.333 0.000
R57 Shock, not elsewhere classified
0.667 0.333 0.000
R64 Cachexia
0.667 0.333 0.000
R58 Haemorrhage, not elsewhere classified
0.667 0.333 0.000
R54 Senility
0.667 0.333 0.000
M80-M85 Disorders of bone density and structure
0.666 0.333 0.000
R50.9 Fever, unspecified
0.666 0.334 0.000
I80 Phlebitis and thrombophlebitis
0.665 0.335 0.000
I44 Atrioventricular and left bundle-branch block
0.663 0.337 0.000
C60-C63 Malignant neoplasms of male genital organs
0.661 0.339 0.000
D27 Benign neoplasm of ovary
0.658 0.342 0.000
C50-C50 Malignant neoplasm of breast
0.656 0.344 0.000
R56 Convulsions, not elsewhere classified
0.653 0.346 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.653 0.347 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.652 0.348 0.000
R60 Oedema, not elsewhere classified
0.652 0.348 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.652 0.348 0.000
C56 Malignant neoplasm of ovary
0.652 0.348 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.649 0.351 0.000
M91-M94 Chondropathies
0.649 0.351 0.000
M86-M90 Other osteopathies
0.649 0.351 0.000
M65-M68 Disorders of synovium and tendon
0.649 0.351 0.000
M60-M63 Disorders of muscles
0.649 0.351 0.000
M00-M03 Infectious arthropathies
0.649 0.351 0.000
D18 Haemangioma and lymphangioma, any site
0.649 0.351 0.000
K40-K46 Hernia
0.647 0.352 0.000
D50-D53 Nutritional anaemias
0.647 0.353 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.647 0.353 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.646 0.354 0.000
I10-I15 Hypertensive diseases
0.645 0.355 0.000
M50-M54 Other dorsopathies
0.644 0.356 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.644 0.356 0.000
S80-S89 Injuries to the knee and lower leg
0.643 0.357 0.000
G70-G73 Diseases of myoneural junction and muscle
0.642 0.358 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.642 0.358 0.000
G30-G32 Other degenerative diseases of the nervous system
0.642 0.358 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.642 0.358 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.642 0.358 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.642 0.358 0.000
C64-C68 Malignant neoplasms of urinary tract
0.640 0.359 0.000
H60-H62 Diseases of external ear
0.640 0.360 0.000
I83 Varicose veins of lower extremities
0.638 0.361 0.000
C54 Malignant neoplasm of corpus uteri
0.636 0.364 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.636 0.364 0.000
I63.9 Cerebral infarction, unspecified
0.634 0.366 0.000
D25.1 Intramural leiomyoma of uterus
0.631 0.368 0.000
G81 Hemiplegia
0.630 0.370 0.000
I69 Sequelae of cerebrovascular disease
0.630 0.370 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.630 0.370 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.630 0.370 0.000
I62 Other nontraumatic intracranial haemorrhage
0.630 0.370 0.000
I61 Intracerebral haemorrhage
0.630 0.370 0.000
I60 Subarachnoid haemorrhage
0.630 0.370 0.000
D36 Benign neoplasm of other and unspecified sites
0.629 0.371 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.629 0.371 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.629 0.371 0.000
D32 Benign neoplasm of meninges
0.629 0.371 0.000
D31 Benign neoplasm of eye and adnexa
0.629 0.371 0.000
D30 Benign neoplasm of urinary organs
0.629 0.371 0.000
D29 Benign neoplasm of male genital organs
0.629 0.371 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.629 0.371 0.000
D26 Other benign neoplasms of uterus
0.629 0.371 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.629 0.371 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.629 0.371 0.000
D19 Benign neoplasm of mesothelial tissue
0.629 0.371 0.000
D16 Benign neoplasm of bone and articular cartilage
0.629 0.371 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.629 0.371 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.629 0.371 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.629 0.371 0.000
D11 Benign neoplasm of major salivary glands
0.629 0.371 0.000
D10 Benign neoplasm of mouth and pharynx
0.629 0.371 0.000
D34 Benign neoplasm of thyroid gland
0.629 0.371 0.000
D25.0 Submucous leiomyoma of uterus
0.628 0.372 0.000
K80 Cholelithiasis
0.627 0.373 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.627 0.373 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.626 0.374 0.000
G20-G26 Extrapyramidal and movement disorders
0.623 0.376 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.621 0.379 0.000
M48.06 Spinal stenosis (Lumbar region)
0.619 0.381 0.000
K82 Other diseases of gallbladder
0.617 0.383 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.617 0.383 0.000
M06 Other rheumatoid arthritis
0.617 0.383 0.000
T81 Complications of procedures, not elsewhere classified
0.616 0.384 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.614 0.386 0.000
N40 Hyperplasia of prostate
0.614 0.386 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.614 0.386 0.000
T79-T79 Certain early complications of trauma
0.614 0.386 0.000
T66-T78 Other and unspecified effects of external causes
0.614 0.386 0.000
T33-T35 Frostbite
0.614 0.386 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.614 0.386 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.614 0.386 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.614 0.386 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.614 0.386 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.614 0.386 0.000
T00-T07 Injuries involving multiple body regions
0.614 0.386 0.000
S90-S99 Injuries to the ankle and foot
0.614 0.386 0.000
S40-S49 Injuries to the shoulder and upper arm
0.614 0.386 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.614 0.386 0.000
S20-S29 Injuries to the thorax
0.614 0.386 0.000
S10-S19 Injuries to the neck
0.614 0.386 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.612 0.387 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.611 0.388 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.610 0.390 0.000
S60-S69 Injuries to the wrist and hand
0.609 0.391 0.000
R10 Abdominal and pelvic pain
0.609 0.391 0.000
S70-S79 Injuries to the hip and thigh
0.605 0.395 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.604 0.396 0.000
C73 Malignant neoplasm of thyroid gland
0.603 0.397 0.000
M49 Spondylopathies in diseases classified elsewhere
0.600 0.400 0.000
M46 Other inflammatory spondylopathies
0.600 0.400 0.000
M45 Ankylosing spondylitis
0.600 0.400 0.000
K76 Other diseases of liver
0.598 0.402 0.000
S50-S59 Injuries to the elbow and forearm
0.597 0.403 0.000
M13 Other arthritis
0.595 0.405 0.000
I67.9 Cerebrovascular disease, unspecified
0.595 0.405 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.595 0.405 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.593 0.407 0.000
H65 Nonsuppurative otitis media
0.593 0.407 0.000
N42 Other disorders of prostate
0.593 0.407 0.000
R69 Unknown and unspecified causes of morbidity
0.592 0.408 0.000
M48.09 Spinal stenosis (Site unspecified)
0.591 0.409 0.000
R63 Symptoms and signs concerning food and fluid intake
0.591 0.409 0.000
G56.0 Carpal tunnel syndrome
0.590 0.410 0.000
K35-K38 Diseases of appendix
0.589 0.411 0.000
I35 Nonrheumatic aortic valve disorders
0.589 0.411 0.000
S00-S09 Injuries to the head
0.588 0.412 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.587 0.413 0.000
I84.1 Internal haemorrhoids with other complications
0.586 0.414 0.000
D60-D64 Aplastic and other anaemias
0.586 0.414 0.000
I52 Other heart disorders in diseases classified elsewhere
0.586 0.414 0.000
I48 Atrial fibrillation and flutter
0.586 0.414 0.000
I45 Other conduction disorders
0.586 0.414 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.586 0.414 0.000
I42 Cardiomyopathy
0.586 0.414 0.000
I41 Myocarditis in diseases classified elsewhere
0.586 0.414 0.000
I40 Acute myocarditis
0.586 0.414 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.586 0.414 0.000
I37 Pulmonary valve disorders
0.586 0.414 0.000
I36 Nonrheumatic tricuspid valve disorders
0.586 0.414 0.000
I33 Acute and subacute endocarditis
0.586 0.414 0.000
I32 Pericarditis in diseases classified elsewhere
0.586 0.414 0.000
I31 Other diseases of pericardium
0.586 0.414 0.000
I30 Acute pericarditis
0.586 0.414 0.000
I38 Endocarditis, valve unspecified
0.586 0.414 0.000
I95 Hypotension
0.585 0.415 0.000
H80-H83 Diseases of inner ear
0.584 0.416 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.584 0.416 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.584 0.416 0.000
L60-L75 Disorders of skin appendages
0.584 0.416 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.582 0.417 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.582 0.417 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.582 0.417 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.582 0.417 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.582 0.417 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.582 0.417 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.581 0.418 0.000
D22.5 Melanocytic naevi of trunk
0.581 0.419 0.000
I67.8 Other specified cerebrovascular diseases
0.580 0.420 0.000
I46.9 Cardiac arrest, unspecified
0.580 0.420 0.000
N50 Other disorders of male genital organs
0.579 0.421 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.576 0.424 0.000
C25 Malignant neoplasm of pancreas
0.576 0.424 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.576 0.424 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.576 0.424 0.000
C21 Malignant neoplasm of anus and anal canal
0.576 0.424 0.000
C17 Malignant neoplasm of small intestine
0.576 0.424 0.000
C16 Malignant neoplasm of stomach
0.576 0.424 0.000
C15 Malignant neoplasm of oesophagus
0.576 0.424 0.000
C23 Malignant neoplasm of gallbladder
0.576 0.424 0.000
K55-K64 Other diseases of intestines
0.574 0.426 0.000
K90-K93 Other diseases of the digestive system
0.573 0.427 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.572 0.427 0.000
M20-M25 Other joint disorders
0.572 0.428 0.000
K70 Alcoholic liver disease
0.572 0.428 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.572 0.428 0.000
C53 Malignant neoplasm of cervix uteri
0.572 0.428 0.000
C51 Malignant neoplasm of vulva
0.572 0.428 0.000
C58 Malignant neoplasm of placenta
0.572 0.428 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.572 0.428 0.000
C52 Malignant neoplasm of vagina
0.572 0.428 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.571 0.429 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.570 0.429 0.000
Chapter I Certain infectious and parasitic diseases
0.568 0.432 0.000
N20-N23 Urolithiasis
0.568 0.432 0.000
I34.0 Mitral (valve) insufficiency
0.568 0.432 0.000
R10.4 Other and unspecified abdominal pain
0.567 0.433 0.000
C20 Malignant neoplasm of rectum
0.567 0.433 0.000
K52 Other non-infective gastro-enteritis and colitis
0.565 0.435 0.000
D80-D89 Certain disorders involving the immune mechanism
0.565 0.435 0.000
D55-D59 Haemolytic anaemias
0.565 0.435 0.000
O00-O08 Pregnancy with abortive outcome
0.564 0.436 0.000
G47 Sleep disorders
0.564 0.436 0.000
N41 Inflammatory diseases of prostate
0.562 0.437 0.000
Z12 Special screening examination for neoplasms
0.562 0.438 0.000
M47.8 Other spondylosis
0.562 0.438 0.000
F99-F99 Unspecified mental disorder
0.561 0.439 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.561 0.439 0.000
F80-F89 Disorders of psychological development
0.561 0.439 0.000
F70-F79 Mental retardation
0.561 0.439 0.000
F60-F69 Disorders of adult personality and behaviour
0.561 0.439 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.561 0.439 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.561 0.439 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.561 0.439 0.000
D25.2 Subserosal leiomyoma of uterus
0.561 0.439 0.000
D24 Benign neoplasm of breast
0.559 0.441 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.557 0.443 0.000
R50.8 Other specified fever
0.557 0.443 0.000
R50.2 Drug-induced fever
0.557 0.443 0.000
R50.1 Persistent fever
0.557 0.443 0.000
R50.0 Fever with chills
0.557 0.443 0.000
C18.9 Colon, unspecified
0.556 0.444 0.000
R47 Speech disturbances, not elsewhere classified
0.553 0.446 0.000
C18.7 Sigmoid colon
0.553 0.447 0.000
K81 Cholecystitis
0.552 0.448 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.551 0.448 0.000
G81.9 Hemiplegia, unspecified
0.551 0.449 0.000
N10-N16 Renal tubulo-interstitial diseases
0.550 0.449 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.550 0.450 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.550 0.450 0.000
T87 Complications peculiar to reattachment and amputation
0.550 0.450 0.000
T86 Failure and rejection of transplanted organs and tissues
0.550 0.450 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.550 0.450 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.550 0.450 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.550 0.450 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.548 0.452 0.000
R17 Unspecified jaundice
0.547 0.453 0.000
R10.3 Pain localised to other parts of lower abdomen
0.546 0.454 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.546 0.454 0.000
G58 Other mononeuropathies
0.546 0.454 0.000
G54 Nerve root and plexus disorders
0.546 0.454 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.546 0.454 0.000
G52 Disorders of other cranial nerves
0.546 0.454 0.000
G51 Facial nerve disorders
0.546 0.454 0.000
G50 Disorders of trigeminal nerve
0.546 0.454 0.000
D23.6 Skin of upper limb, including shoulder
0.545 0.454 0.000
I49.0 Ventricular fibrillation and flutter
0.545 0.455 0.000
I44.2 Atrioventricular block, complete
0.544 0.456 0.000
N99-N99 Other disorders of the genitourinary system
0.543 0.457 0.000
N00-N08 Glomerular diseases
0.543 0.457 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.543 0.457 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.543 0.457 0.000
G93 Other disorders of brain
0.543 0.457 0.000
M48.9 Spondylopathy, unspecified
0.541 0.458 0.000
M48.8 Other specified spondylopathies
0.541 0.458 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.541 0.458 0.000
M48.4 Fatigue fracture of vertebra
0.541 0.458 0.000
M48.3 Traumatic spondylopathy
0.541 0.458 0.000
M48.2 Kissing spine
0.541 0.458 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.541 0.458 0.000
R49 Voice disturbances
0.540 0.460 0.000
M14 Arthropathies in other diseases classified elsewhere
0.539 0.461 0.000
M12 Other specific arthropathies
0.539 0.461 0.000
M11 Other crystal arthropathies
0.539 0.461 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.539 0.461 0.000
M08 Juvenile arthritis
0.539 0.461 0.000
M07 Psoriatic and enteropathic arthropathies
0.539 0.461 0.000
M05 Seropositive rheumatoid arthritis
0.539 0.461 0.000
O85-O92 Complications predominantly related to the puerperium
0.538 0.462 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.538 0.462 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.538 0.462 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.538 0.462 0.000
I99 Other and unspecified disorders of circulatory system
0.538 0.462 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.538 0.462 0.000
K86 Other diseases of pancreas
0.538 0.462 0.000
K85 Acute pancreatitis
0.538 0.462 0.000
M47.9 Spondylosis, unspecified
0.538 0.462 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.538 0.462 0.000
M43 Other deforming dorsopathies
0.537 0.463 0.000
K66 Other disorders of peritoneum
0.536 0.464 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.535 0.465 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.535 0.465 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.534 0.466 0.000
C74 Malignant neoplasm of adrenal gland
0.534 0.466 0.000
N48 Other disorders of penis
0.533 0.467 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.533 0.467 0.000
Z02 Examination and encounter for administrative purposes
0.533 0.467 0.000
D50 Iron deficiency anaemia
0.532 0.468 0.000
G83 Other paralytic syndromes
0.531 0.468 0.000
G82 Paraplegia and tetraplegia
0.531 0.468 0.000
G80 Infantile cerebral palsy
0.531 0.468 0.000
I51 Complications and ill-defined descriptions of heart disease
0.531 0.469 0.000
Z13 Special screening examination for other diseases and disorders
0.531 0.469 0.000
Z04 Examination and observation for other reasons
0.531 0.469 0.000
L50-L54 Urticaria and erythema
0.529 0.470 0.000
L10-L14 Bullous disorders
0.529 0.470 0.000
K83 Other diseases of biliary tract
0.529 0.471 0.000
N25-N29 Other disorders of kidney and ureter
0.529 0.471 0.000
M70-M79 Other soft tissue disorders
0.528 0.472 0.000
H90-H95 Other disorders of ear
0.528 0.472 0.000
I63.8 Other cerebral infarction
0.528 0.472 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.528 0.472 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.528 0.472 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.528 0.472 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.528 0.472 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.528 0.472 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.528 0.472 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.528 0.472 0.000
R26 Abnormalities of gait and mobility
0.528 0.472 0.000
I08 Multiple valve diseases
0.527 0.473 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.527 0.473 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.526 0.474 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.526 0.474 0.000
I67.5 Moyamoya disease
0.526 0.474 0.000
I67.4 Hypertensive encephalopathy
0.526 0.474 0.000
I67.3 Progressive vascular leukoencephalopathy
0.526 0.474 0.000
I67.2 Cerebral atherosclerosis
0.526 0.474 0.000
I67.1 Cerebral aneurysm, nonruptured
0.526 0.474 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.526 0.474 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.526 0.474 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.526 0.474 0.000
H25-H28 Disorders of lens
0.525 0.475 0.000
K82.8 Other specified diseases of gallbladder
0.522 0.478 0.000
O60-O75 Complications of labour and delivery
0.521 0.478 0.000
C54.1 Endometrium
0.521 0.479 0.000
I20-I25 Ischaemic heart diseases
0.521 0.479 0.000
L40-L45 Papulosquamous disorders
0.520 0.479 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.520 0.479 0.000
I84.8 Unspecified haemorrhoids with other complications
0.520 0.480 0.000
M06.9 Rheumatoid arthritis, unspecified
0.520 0.480 0.000
K77 Liver disorders in diseases classified elsewhere
0.519 0.481 0.000
K75 Other inflammatory liver diseases
0.519 0.481 0.000
K74 Fibrosis and cirrhosis of liver
0.519 0.481 0.000
K73 Chronic hepatitis, not elsewhere classified
0.519 0.481 0.000
K72 Hepatic failure, not elsewhere classified
0.519 0.481 0.000
K71 Toxic liver disease
0.519 0.481 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.519 0.481 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.519 0.481 0.000
N45 Orchitis and epididymitis
0.519 0.481 0.000
N46 Male infertility
0.519 0.481 0.000
N44 Torsion of testis
0.519 0.481 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.518 0.481 0.000
R21 Rash and other nonspecific skin eruption
0.518 0.482 0.000
M10 Gout
0.518 0.482 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.518 0.482 0.000
K04 Diseases of pulp and periapical tissues
0.518 0.482 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.515 0.485 0.000
H60 Otitis externa
0.515 0.485 0.000
H43-H45 Disorders of vitreous body and globe
0.515 0.485 0.000
I09 Other rheumatic heart diseases
0.514 0.486 0.000
I07 Rheumatic tricuspid valve diseases
0.514 0.486 0.000
I06 Rheumatic aortic valve diseases
0.514 0.486 0.000
I05 Rheumatic mitral valve diseases
0.514 0.486 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.514 0.486 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.514 0.486 0.000
Y35-Y36 Legal intervention and operations of war
0.514 0.486 0.000
Y10-Y34 Event of undetermined intent
0.514 0.486 0.000
Y00-Y09 Assault
0.514 0.486 0.000
X85-X99 Assault
0.514 0.486 0.000
X60-X84 Intentional self-harm
0.514 0.486 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.514 0.486 0.000
X50-X57 Overexertion, travel and privation
0.514 0.486 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.514 0.486 0.000
X30-X39 Exposure to forces of nature
0.514 0.486 0.000
X20-X29 Contact with venomous animals and plants
0.514 0.486 0.000
X10-X19 Contact with heat and hot substances
0.514 0.486 0.000
X00-X09 Exposure to smoke, fire and flames
0.514 0.486 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.514 0.486 0.000
W75-W84 Other accidental threats to breathing
0.514 0.486 0.000
W65-W74 Accidental drowning and submersion
0.514 0.486 0.000
W50-W64 Exposure to animate mechanical forces
0.514 0.486 0.000
W20-W49 Exposure to inanimate mechanical forces
0.514 0.486 0.000
V98-V99 Other and unspecified transport accidents
0.514 0.486 0.000
V95-V97 Air and space transport accidents
0.514 0.486 0.000
V90-V94 Water transport accidents
0.514 0.486 0.000
V80-V89 Other land transport accidents
0.514 0.486 0.000
V70-V79 Bus occupant injured in transport accident
0.514 0.486 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.514 0.486 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.514 0.486 0.000
V40-V49 Car occupant injured in transport accident
0.514 0.486 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.514 0.486 0.000
V20-V29 Motorcycle rider injured in transport accident
0.514 0.486 0.000
V10-V19 Pedal cyclist injured in transport accident
0.514 0.486 0.000
V01-V09 Pedestrian injured in transport accident
0.514 0.486 0.000
R23 Other skin changes
0.514 0.486 0.000
R52.1 Chronic intractable pain
0.513 0.487 0.000
L20-L30 Dermatitis and eczema
0.512 0.487 0.000
F30-F39 Mood [affective] disorders
0.512 0.488 0.000
I49.9 Cardiac arrhythmia, unspecified
0.509 0.490 0.000
K40 Inguinal hernia
0.509 0.491 0.000
L03 Cellulitis
0.509 0.491 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.509 0.491 0.000
M18 Arthrosis of first carpometacarpal joint
0.509 0.491 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.508 0.492 0.000
O80-O84 Delivery
0.507 0.492 0.000
G56.2 Lesion of ulnar nerve
0.507 0.493 0.000
G57 Mononeuropathies of lower limb
0.507 0.493 0.000
P90-P96 Other disorders originating in the perinatal period
0.506 0.493 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.506 0.493 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.506 0.493 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.506 0.493 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.506 0.493 0.000
P35-P39 Infections specific to the perinatal period
0.506 0.493 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.506 0.493 0.000
P10-P15 Birth trauma
0.506 0.493 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.506 0.493 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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