TreeWAS – Variant ID: rs2916733

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z36.8 Other antenatal screening	0.013	0.987	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.012	0.988	0.000
C77.3 Axillary and upper limb lymph nodes	0.009	0.991	0.000
I73.9 Peripheral vascular disease, unspecified	0.008	0.992	0.000
I78.1 Naevus, nonneoplastic	0.007	0.993	0.000
M25.77 Osteophyte (Ankle and foot)	0.005	0.995	0.000
I78 Diseases of capillaries	0.005	0.995	0.000
M13.94 Arthritis, unspecified (Hand)	0.000	0.995	0.005
C34.3 Lower lobe, bronchus or lung	0.000	0.995	0.005
S80.9 Superficial injury of lower leg, unspecified	0.000	0.995	0.005
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.995	0.005
Z36 Antenatal screening	0.005	0.995	0.000
Z48.9 Surgical follow-up care, unspecified	0.000	0.996	0.004
K07.3 Anomalies of tooth position	0.004	0.996	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.000	0.996	0.004
I73 Other peripheral vascular diseases	0.004	0.996	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
M13.9 Arthritis, unspecified	0.000	0.996	0.004
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.996	0.004
I70-I79 Diseases of arteries, arterioles and capillaries	0.004	0.996	0.000
I78.9 Disease of capillaries, unspecified	0.004	0.996	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.004	0.996	0.000
N36.8 Other specified disorders of urethra	0.000	0.996	0.004
Z36.0 Antenatal screening for chromosomal anomalies	0.004	0.996	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.004	0.996	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.004	0.996	0.000
J86.9 Pyothorax without fistula	0.004	0.996	0.000
I71 Aortic aneurysm and dissection	0.004	0.996	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.004	0.996	0.000
I74 Arterial embolism and thrombosis	0.004	0.996	0.000
C83.3 Large cell (diffuse)	0.000	0.996	0.004
Z36.5 Antenatal screening for isoimmunisation	0.003	0.996	0.000
I78.8 Other diseases of capillaries	0.003	0.996	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.997	0.003
M62.88 Other specified disorders of muscle (Other)	0.003	0.997	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.003	0.997	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
Z95.0 Presence of cardiac pacemaker	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.997	0.003
I71.0 Dissection of aorta [any part]	0.003	0.997	0.000
K70.4 Alcoholic hepatic failure	0.003	0.997	0.000
M13.93 Arthritis, unspecified (Forearm)	0.000	0.997	0.003
I74.9 Embolism and thrombosis of unspecified artery	0.003	0.997	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.003	0.997	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.003	0.997	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M41.9 Scoliosis, unspecified	0.000	0.997	0.003
I71.8 Aortic aneurysm of unspecified site, ruptured	0.003	0.997	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.003	0.997	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.003	0.997	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.003	0.997	0.000
I70 Atherosclerosis	0.003	0.997	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.003	0.997	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.997	0.003
M62.8 Other specified disorders of muscle	0.003	0.997	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.003	0.997	0.000
F33.9 Recurrent depressive disorder, unspecified	0.003	0.997	0.000
I72 Other aneurysm	0.003	0.997	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.997	0.003
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
I77 Other disorders of arteries and arterioles	0.003	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.002	0.997	0.000
I70.0 Atherosclerosis of aorta	0.002	0.997	0.000
I77.0 Arteriovenous fistula, acquired	0.002	0.997	0.000
Z36.9 Antenatal screening, unspecified	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.002
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
I70.1 Atherosclerosis of renal artery	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.000	0.998	0.002
M13.98 Arthritis, unspecified (Other)	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.998	0.002
I74.8 Embolism and thrombosis of other arteries	0.002	0.998	0.000
I72.2 Aneurysm of renal artery	0.002	0.998	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
K90.9 Intestinal malabsorption, unspecified	0.002	0.998	0.000
R60.0 Localised oedema	0.000	0.998	0.002
I72.6 Aneurysm and dissection of vertebral artery	0.002	0.998	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.002	0.998	0.000
I72.1 Aneurysm of artery of upper extremity	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
K35 Acute appendicitis	0.002	0.998	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
I79.1 Aortitis in diseases classified elsewhere	0.002	0.998	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
S41.0 Open wound of shoulder	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
I77.1 Stricture of artery	0.002	0.998	0.000
I72.9 Aneurysm of unspecified site	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
Q63.2 Ectopic kidney	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
I77.5 Necrosis of artery	0.002	0.998	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.998	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.998	0.000
I77.2 Rupture of artery	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
L53.9 Erythematous condition, unspecified	0.000	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.002	0.998	0.000
J86 Pyothorax	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.998	0.002
K70 Alcoholic liver disease	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.998	0.002
I70.81 Atherosclerosis of other arteries (with gangrene)	0.002	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.002	0.998	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.002	0.998	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.002	0.998	0.000
K82.8 Other specified diseases of gallbladder	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
M62 Other disorders of muscle	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
Z13.5 Special screening examination for eye and ear disorders	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
J93.9 Pneumothorax, unspecified	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
N36.9 Urethral disorder, unspecified	0.000	0.998	0.002
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.998	0.000
I77.8 Other specified disorders of arteries and arterioles	0.002	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
D69.0 Allergic purpura	0.000	0.998	0.002
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.998	0.000
M62.6 Muscle strain	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
K07 Dentofacial anomalies [including malocclusion]	0.002	0.998	0.000
K90 Intestinal malabsorption	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.002	0.998	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
K07.4 Malocclusion, unspecified	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
N36 Other disorders of urethra	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.998	0.002
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.002
D69.1 Qualitative platelet defects	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
E10.9 Without complications	0.000	0.998	0.002
M62.9 Disorder of muscle, unspecified	0.002	0.998	0.000
M62.4 Contracture of muscle	0.002	0.998	0.000
M62.3 Immobility syndrome (paraplegic)	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.998	0.000
M62.0 Diastasis of muscle	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
N60.3 Fibrosclerosis of breast	0.000	0.998	0.002
Q24.6 Congenital heart block	0.001	0.998	0.000
Q24.5 Malformation of coronary vessels	0.001	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.001	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.998	0.000
Q24.2 Cor triatriatum	0.001	0.998	0.000
Q24.1 Levocardia	0.001	0.998	0.000
Q24.0 Dextrocardia	0.001	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.001	0.998	0.000
Q64.4 Malformation of urachus	0.001	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.001	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.001	0.998	0.000
Q64.0 Epispadias	0.001	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.998	0.000
Q90 Down's syndrome	0.001	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.001	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.998	0.000
Q89.8 Other specified congenital malformations	0.001	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.998	0.000
Q89.4 Conjoined twins	0.001	0.998	0.000
Q89.3 Situs inversus	0.001	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.998	0.000
Q89.0 Congenital malformations of spleen	0.001	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
C50.4 Upper-outer quadrant of breast	0.002	0.998	0.000
H52.2 Astigmatism	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.001	0.998	0.000
Q61.8 Other cystic kidney diseases	0.001	0.998	0.000
Q61.4 Renal dysplasia	0.001	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.001	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.000	0.998	0.002
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.998	0.000
Q52.5 Fusion of labia	0.001	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.001	0.998	0.000
Q52.3 Imperforate hymen	0.001	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.998	0.000
Q52.1 Doubling of vagina	0.001	0.998	0.000
Q52.0 Congenital absence of vagina	0.001	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.001	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q66.2 Metatarsus varus	0.001	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000
Q67.1 Compression facies	0.001	0.998	0.000
Q67.0 Facial asymmetry	0.001	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.001	0.998	0.000
R60.1 Generalised oedema	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
Q66.7 Pes cavus	0.001	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.002
Q98.4 Klinefelter's syndrome, unspecified	0.001	0.998	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
Q06 Other congenital malformations of spinal cord	0.001	0.998	0.000
Q03 Congenital hydrocephalus	0.001	0.998	0.000
Q01 Encephalocele	0.001	0.998	0.000
Q00 Anencephaly and similar malformations	0.001	0.998	0.000
Q02 Microcephaly	0.001	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
J02.9 Acute pharyngitis, unspecified	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.001	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.001	0.998	0.000
Q53.0 Ectopic testis	0.001	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.001	0.998	0.000
Q33 Congenital malformations of lung	0.001	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.998	0.000
Q31 Congenital malformations of larynx	0.001	0.998	0.000
Q30 Congenital malformations of nose	0.001	0.998	0.000
Q37 Cleft palate with cleft lip	0.001	0.998	0.000
Q36 Cleft lip	0.001	0.998	0.000
Q35 Cleft palate	0.001	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.001	0.998	0.000
K07.2 Anomalies of dental arch relationship	0.001	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.001	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.001	0.998	0.000
Q04.5 Megalencephaly	0.001	0.998	0.000
Q04.4 Septo-optic dysplasia	0.001	0.998	0.000
Q04.3 Other reduction deformities of brain	0.001	0.998	0.000
Q04.2 Holoprosencephaly	0.001	0.998	0.000
Q04.1 Arhinencephaly	0.001	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.001	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.998	0.000
Q20.4 Double inlet ventricle	0.001	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.998	0.000
Q20.2 Double outlet left ventricle	0.001	0.998	0.000
Q20.1 Double outlet right ventricle	0.001	0.998	0.000
Q20.0 Common arterial trunk	0.001	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.998	0.000
Q22.5 Ebstein's anomaly	0.001	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.001	0.998	0.000
Q22.0 Pulmonary valve atresia	0.001	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.1 Persistent left superior vena cava	0.001	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.001	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.001	0.998	0.000
Q79.4 Prune belly syndrome	0.001	0.998	0.000
Q79.3 Gastroschisis	0.001	0.998	0.000
Q79.2 Exomphalos	0.001	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.001	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.001	0.998	0.000
S02.0 Fracture of vault of skull	0.000	0.998	0.002
M41 Scoliosis	0.000	0.998	0.001
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.001	0.998	0.000
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.998	0.000
M62.68 Muscle strain (Other)	0.001	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.998	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.001	0.998	0.000
M62.64 Muscle strain (Hand)	0.001	0.998	0.000
M62.63 Muscle strain (Forearm)	0.001	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.998	0.000
D68.0 Von Willebrand's disease	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
J39.2 Other diseases of pharynx	0.000	0.998	0.002
K07.8 Other dentofacial anomalies	0.001	0.998	0.000
K07.5 Dentofacial functional abnormalities	0.001	0.998	0.000
K07.0 Major anomalies of jaw size	0.001	0.998	0.000
K90.8 Other intestinal malabsorption	0.001	0.998	0.000
K90.3 Pancreatic steatorrhoea	0.001	0.998	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.001	0.998	0.000
K90.1 Tropical sprue	0.001	0.998	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.998	0.001
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.001	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.001	0.998	0.000
Q25.3 Stenosis of aorta	0.001	0.998	0.000
Q25.2 Atresia of aorta	0.001	0.998	0.000
Q25.0 Patent ductus arteriosus	0.001	0.998	0.000
Q61.5 Medullary cystic kidney	0.001	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.998	0.000
Q62.6 Malposition of ureter	0.001	0.998	0.000
Q62.4 Agenesis of ureter	0.001	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.998	0.000
Q62.2 Congenital megaloureter	0.001	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.001	0.998	0.000
Q62.0 Congenital hydronephrosis	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations