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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3748140
log Bayes Factor = 15.9864
Chromosome 8   position 8,999,019  (GRCh37) Explore rs3748140 on Ensembl!
Variant rs3748140 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
K55-K64 Other diseases of intestines
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.990 0.010 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.988 0.012 0.000
K59 Other functional intestinal disorders
0.985 0.015 0.000
M54 Dorsalgia
0.983 0.017 0.000
O60-O75 Complications of labour and delivery
0.981 0.019 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.980 0.020 0.000
S80-S89 Injuries to the knee and lower leg
0.978 0.022 0.000
F41 Other anxiety disorders
0.970 0.030 0.000
K59.0 Constipation
0.970 0.030 0.000
K51 Ulcerative colitis
0.966 0.034 0.000
Chapter XIV Diseases of the genitourinary system
0.952 0.048 0.000
M70-M79 Other soft tissue disorders
0.952 0.048 0.000
K50 Crohn's disease [regional enteritis]
0.951 0.049 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.951 0.049 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.942 0.058 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.940 0.060 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.935 0.065 0.000
N60-N64 Disorders of breast
0.932 0.068 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.930 0.070 0.000
R04 Haemorrhage from respiratory passages
0.929 0.071 0.000
R07 Pain in throat and chest
0.926 0.074 0.000
K81 Cholecystitis
0.925 0.075 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.925 0.075 0.000
K51.9 Ulcerative colitis, unspecified
0.924 0.076 0.000
F41.2 Mixed anxiety and depressive disorder
0.924 0.076 0.000
Chapter VII Diseases of the eye and adnexa
0.923 0.077 0.000
S82 Fracture of lower leg, including ankle
0.917 0.083 0.000
M54.9 Dorsalgia, unspecified
0.915 0.085 0.000
N17-N19 Renal failure
0.914 0.086 0.000
R50-R69 General symptoms and signs
0.911 0.089 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.911 0.089 0.000
M45-M49 Spondylopathies
0.909 0.091 0.000
M20-M25 Other joint disorders
0.905 0.095 0.000
O70 Perineal laceration during delivery
0.902 0.098 0.000
R05 Cough
0.897 0.103 0.000
R07.4 Chest pain, unspecified
0.897 0.103 0.000
N18 Chronic renal failure
0.895 0.105 0.000
K83 Other diseases of biliary tract
0.888 0.112 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.885 0.115 0.000
M50 Cervical disk disorders
0.885 0.115 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.884 0.116 0.000
R04.2 Haemoptysis
0.882 0.118 0.000
K82 Other diseases of gallbladder
0.879 0.121 0.000
M54.3 Sciatica
0.877 0.123 0.000
M54.5 Low back pain
0.873 0.127 0.000
N64 Other disorders of breast
0.873 0.127 0.000
Chapter VIII Diseases of the ear and mastoid process
0.872 0.128 0.000
K50.9 Crohn's disease, unspecified
0.871 0.129 0.000
K52 Other non-infective gastro-enteritis and colitis
0.868 0.132 0.000
O47 False labour
0.868 0.132 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.865 0.135 0.000
K81.1 Chronic cholecystitis
0.864 0.136 0.000
K59.3 Megacolon, not elsewhere classified
0.862 0.138 0.000
M25 Other joint disorders, not elsewhere classified
0.858 0.142 0.000
K90-K93 Other diseases of the digestive system
0.853 0.147 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.852 0.148 0.000
T43.2 Other and unspecified antidepressants
0.851 0.149 0.000
Chapter XXI Factors influencing health status and contact with health services
0.848 0.152 0.000
N18.3 Chronic kidney disease, stage 3
0.846 0.154 0.000
S81 Open wound of lower leg
0.844 0.156 0.000
E70-E90 Metabolic disorders
0.842 0.158 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.841 0.159 0.000
T66-T78 Other and unspecified effects of external causes
0.836 0.164 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.835 0.165 0.000
F41.1 Generalised anxiety disorder
0.834 0.165 0.000
R45 Symptoms and signs involving emotional state
0.832 0.168 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.830 0.170 0.000
K86 Other diseases of pancreas
0.829 0.171 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.826 0.174 0.000
Chapter XX External causes of morbidity and mortality
0.826 0.174 0.000
E65-E68 Obesity and other hyperalimentation
0.819 0.181 0.000
N99-N99 Other disorders of the genitourinary system
0.818 0.182 0.000
Chapter II Neoplasms
0.818 0.182 0.000
K63 Other diseases of intestine
0.815 0.185 0.000
O80-O84 Delivery
0.814 0.186 0.000
H53-H54 Visual disturbances and blindness
0.814 0.186 0.000
S80 Superficial injury of lower leg
0.813 0.187 0.000
N18.9 Chronic renal failure, unspecified
0.811 0.189 0.000
O70.0 First degree perineal laceration during delivery
0.811 0.189 0.000
E50-E64 Other nutritional deficiencies
0.811 0.189 0.000
F41.9 Anxiety disorder, unspecified
0.810 0.190 0.000
R63 Symptoms and signs concerning food and fluid intake
0.809 0.191 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.809 0.191 0.000
F60-F69 Disorders of adult personality and behaviour
0.808 0.192 0.000
Chapter XXII Codes for special purposes
0.807 0.193 0.000
T39.1 4-Aminophenol derivatives
0.807 0.193 0.000
M25.5 Pain in joint
0.806 0.194 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.806 0.194 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.806 0.194 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.806 0.194 0.000
O63 Long labour
0.805 0.195 0.000
K61 Abscess of anal and rectal regions
0.805 0.195 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.805 0.195 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.804 0.196 0.000
M79.6 Pain in limb
0.803 0.197 0.000
Chapter VI Diseases of the nervous system
0.802 0.198 0.000
K04 Diseases of pulp and periapical tissues
0.800 0.199 0.000
M47 Spondylosis
0.800 0.200 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.799 0.201 0.000
K11 Diseases of salivary glands
0.798 0.202 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.797 0.203 0.000
Z37 Outcome of delivery
0.796 0.204 0.000
R59 Enlarged lymph nodes
0.796 0.204 0.000
K08 Other disorders of teeth and supporting structures
0.796 0.204 0.000
O72 Postpartum haemorrhage
0.794 0.206 0.000
M75 Shoulder lesions
0.791 0.209 0.000
K50.1 Crohn's disease of large intestine
0.791 0.209 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.791 0.209 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.790 0.210 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.790 0.210 0.000
M54.39 Sciatica (Site unspecified)
0.789 0.211 0.000
T79-T79 Certain early complications of trauma
0.789 0.211 0.000
Z37.0 Single live birth
0.788 0.212 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.787 0.212 0.000
S82.6 Fracture of lateral malleolus
0.787 0.213 0.000
K83.1 Obstruction of bile duct
0.784 0.216 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.781 0.219 0.000
R42 Dizziness and giddiness
0.779 0.221 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.778 0.222 0.000
N63 Unspecified lump in breast
0.777 0.223 0.000
N62 Hypertrophy of breast
0.771 0.229 0.000
M54.4 Lumbago with sciatica
0.770 0.230 0.000
N64.5 Other signs and symptoms in breast
0.769 0.231 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.769 0.231 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.769 0.231 0.000
O66 Other obstructed labour
0.767 0.232 0.000
N00-N08 Glomerular diseases
0.767 0.233 0.000
M48 Other spondylopathies
0.765 0.235 0.000
H55-H59 Other disorders of eye and adnexa
0.764 0.236 0.000
R63.4 Abnormal weight loss
0.764 0.236 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.764 0.236 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.236 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.763 0.237 0.000
K59.8 Other specified functional intestinal disorders
0.762 0.238 0.000
M54.56 Low back pain (Lumbar region)
0.757 0.243 0.000
N61 Inflammatory disorders of breast
0.757 0.243 0.000
S90-S99 Injuries to the ankle and foot
0.756 0.244 0.000
S60-S69 Injuries to the wrist and hand
0.755 0.245 0.000
K92 Other diseases of digestive system
0.755 0.245 0.000
R50 Fever of unknown origin
0.754 0.246 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.754 0.246 0.000
O36 Maternal care for other known or suspected foetal problems
0.753 0.247 0.000
K50.8 Other Crohn's disease
0.753 0.247 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.751 0.249 0.000
H10-H13 Disorders of conjunctiva
0.750 0.249 0.000
Z72 Problems related to lifestyle
0.750 0.250 0.000
D60-D64 Aplastic and other anaemias
0.750 0.250 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.749 0.251 0.000
S40-S49 Injuries to the shoulder and upper arm
0.749 0.251 0.000
S82.5 Fracture of medial malleolus
0.748 0.252 0.000
O70.1 Second degree perineal laceration during delivery
0.744 0.256 0.000
M75.1 Rotator cuff syndrome
0.743 0.257 0.000
S20-S29 Injuries to the thorax
0.743 0.257 0.000
M54.2 Cervicalgia
0.743 0.257 0.000
C15-C26 Malignant neoplasms of digestive organs
0.742 0.258 0.000
M50.2 Other cervical disk displacement
0.742 0.258 0.000
M25.56 Pain in joint (Lower leg)
0.742 0.258 0.000
R52 Pain, not elsewhere classified
0.742 0.258 0.000
S00-S09 Injuries to the head
0.742 0.258 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.741 0.259 0.000
S89 Other and unspecified injuries of lower leg
0.740 0.260 0.000
K51.4 Pseudopolyposis of colon
0.740 0.260 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.738 0.262 0.000
M86-M90 Other osteopathies
0.737 0.263 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.737 0.263 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.737 0.263 0.000
R45.8 Other symptoms and signs involving emotional state
0.734 0.266 0.000
K82.9 Disease of gallbladder, unspecified
0.734 0.266 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.734 0.266 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.733 0.267 0.000
E66 Obesity
0.732 0.268 0.000
H53 Visual disturbances
0.732 0.268 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.731 0.269 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.731 0.269 0.000
N64.1 Fat necrosis of breast
0.731 0.269 0.000
M80-M85 Disorders of bone density and structure
0.728 0.272 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.728 0.272 0.000
R60 Oedema, not elsewhere classified
0.727 0.273 0.000
K02 Dental caries
0.727 0.273 0.000
E86 Volume depletion
0.727 0.273 0.000
K58 Irritable bowel syndrome
0.726 0.274 0.000
K82.8 Other specified diseases of gallbladder
0.726 0.274 0.000
K63.8 Other specified diseases of intestine
0.724 0.276 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.276 0.000
M77 Other enthesopathies
0.723 0.277 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.723 0.277 0.000
S82.4 Fracture of fibula alone
0.722 0.278 0.000
M31 Other necrotising vasculopathies
0.722 0.278 0.000
Chapter I Certain infectious and parasitic diseases
0.722 0.278 0.000
K83.0 Cholangitis
0.720 0.280 0.000
F43 Reaction to severe stress, and adjustment disorders
0.720 0.280 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.720 0.280 0.000
T78 Adverse effects, not elsewhere classified
0.720 0.280 0.000
M65-M68 Disorders of synovium and tendon
0.719 0.280 0.000
H02 Other disorders of eyelid
0.719 0.281 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.719 0.281 0.000
K51.8 Other ulcerative colitis
0.719 0.281 0.000
K70-K77 Diseases of liver
0.719 0.281 0.000
E53 Deficiency of other B group vitamins
0.719 0.281 0.000
K92.1 Melaena
0.718 0.282 0.000
O42 Premature rupture of membranes
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.716 0.284 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.716 0.284 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.715 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
D00-D09 In situ neoplasms
0.713 0.287 0.000
M53 Other dorsopathies, not elsewhere classified
0.712 0.288 0.000
F99-F99 Unspecified mental disorder
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F80-F89 Disorders of psychological development
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.712 0.288 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.712 0.288 0.000
F10.1 Harmful use
0.711 0.289 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.711 0.289 0.000
K55 Vascular disorders of intestine
0.711 0.289 0.000
M50.1 Cervical disk disorder with radiculopathy
0.711 0.289 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.710 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.710 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.710 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.710 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.710 0.289 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.710 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.710 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.710 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.710 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.710 0.289 0.000
T36 Poisoning by systemic antibiotics
0.710 0.289 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.710 0.290 0.000
R40 Somnolence, stupor and coma
0.709 0.291 0.000
H65-H75 Diseases of middle ear and mastoid
0.709 0.291 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.709 0.291 0.000
R02 Gangrene, not elsewhere classified
0.708 0.292 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.708 0.292 0.000
K08.3 Retained dental root
0.707 0.293 0.000
K59.9 Functional intestinal disorder, unspecified
0.706 0.294 0.000
K59.4 Anal spasm
0.706 0.294 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.706 0.294 0.000
K59.1 Functional diarrhoea
0.706 0.294 0.000
M25.7 Osteophyte
0.705 0.295 0.000
H43-H45 Disorders of vitreous body and globe
0.705 0.295 0.000
M54.8 Other dorsalgia
0.705 0.295 0.000
M54.6 Pain in thoracic spine
0.705 0.295 0.000
M54.0 Panniculitis affecting regions of neck and back
0.705 0.295 0.000
K50.0 Crohn's disease of small intestine
0.704 0.295 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.704 0.296 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.703 0.297 0.000
O74 Complications of anaesthesia during labour and delivery
0.703 0.297 0.000
O73 Retained placenta and membranes, without haemorrhage
0.703 0.297 0.000
O71 Other obstetric trauma
0.703 0.297 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.703 0.297 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.703 0.297 0.000
O62 Abnormalities of forces of labour
0.703 0.297 0.000
O61 Failed induction of labour
0.703 0.297 0.000
O60 Preterm delivery
0.703 0.297 0.000
M79.7 Fibromyalgia
0.703 0.297 0.000
R07.2 Precordial pain
0.703 0.297 0.000
S81.9 Open wound of lower leg, part unspecified
0.703 0.297 0.000
K81.0 Acute cholecystitis
0.703 0.297 0.000
F48 Other neurotic disorders
0.702 0.298 0.000
F45 Somatoform disorders
0.702 0.298 0.000
F44 Dissociative [conversion] disorders
0.702 0.298 0.000
F42 Obsessive-compulsive disorder
0.702 0.298 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.702 0.298 0.000
T39.0 Salicylates
0.702 0.298 0.000
S82.3 Fracture of lower end of tibia
0.701 0.299 0.000
S88 Traumatic amputation of lower leg
0.701 0.299 0.000
S87 Crushing injury of lower leg
0.701 0.299 0.000
S86 Injury of muscle and tendon at lower leg level
0.701 0.299 0.000
S85 Injury of blood vessels at lower leg level
0.701 0.299 0.000
S84 Injury of nerves at lower leg level
0.701 0.299 0.000
N18.4 Chronic kidney disease, stage 4
0.701 0.299 0.000
S82.2 Fracture of shaft of tibia
0.700 0.300 0.000
K85 Acute pancreatitis
0.699 0.300 0.000
M21 Other acquired deformities of limbs
0.698 0.302 0.000
H80-H83 Diseases of inner ear
0.697 0.303 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.696 0.304 0.000
N64.8 Other specified disorders of breast
0.696 0.304 0.000
H90-H95 Other disorders of ear
0.696 0.304 0.000
F41.8 Other specified anxiety disorders
0.696 0.304 0.000
F41.3 Other mixed anxiety disorders
0.696 0.304 0.000
S80.9 Superficial injury of lower leg, unspecified
0.695 0.305 0.000
K07 Dentofacial anomalies [including malocclusion]
0.693 0.307 0.000
S82.60 Fracture of lateral malleolus (closed)
0.693 0.307 0.000
K51.5 Mucosal proctocolitis
0.693 0.307 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.693 0.307 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.693 0.307 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.691 0.309 0.000
C64-C68 Malignant neoplasms of urinary tract
0.691 0.309 0.000
R04.0 Epistaxis
0.691 0.309 0.000
M51 Other intervertebral disk disorders
0.689 0.311 0.000
R61 Hyperhidrosis
0.689 0.311 0.000
K81.9 Cholecystitis, unspecified
0.688 0.312 0.000
E00-E07 Disorders of thyroid gland
0.687 0.313 0.000
M79.0 Rheumatism, unspecified
0.687 0.313 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.687 0.313 0.000
Z72.1 Alcohol use
0.686 0.314 0.000
R07.0 Pain in throat
0.685 0.315 0.000
M54.1 Radiculopathy
0.684 0.316 0.000
O80 Single spontaneous delivery
0.684 0.316 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.684 0.316 0.000
E66.8 Other obesity
0.683 0.317 0.000
M76 Enthesopathies of lower limb, excluding foot
0.682 0.318 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.682 0.318 0.000
M71 Other bursopathies
0.682 0.318 0.000
S70-S79 Injuries to the hip and thigh
0.682 0.318 0.000
O45 Premature separation of placenta [abruptio placentae]
0.682 0.318 0.000
O44 Placenta praevia
0.682 0.318 0.000
O43 Placental disorders
0.682 0.318 0.000
O41 Other disorders of amniotic fluid and membranes
0.682 0.318 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.682 0.318 0.000
O33 Maternal care for known or suspected disproportion
0.682 0.318 0.000
O31 Complications specific to multiple gestation
0.682 0.318 0.000
O30 Multiple gestation
0.682 0.318 0.000
O40 Polyhydramnios
0.682 0.318 0.000
E20-E35 Disorders of other endocrine glands
0.682 0.318 0.000
S81.0 Open wound of knee
0.682 0.318 0.000
K51.2 Ulcerative (chronic) proctitis
0.679 0.321 0.000
N10-N16 Renal tubulo-interstitial diseases
0.679 0.321 0.000
O47.9 False labour, unspecified
0.678 0.322 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.678 0.322 0.000
O63.1 Prolonged second stage (of labour)
0.677 0.323 0.000
F40 Phobic anxiety disorders
0.676 0.324 0.000
F60 Specific personality disorders
0.676 0.324 0.000
T43.9 Psychotropic drug, unspecified
0.675 0.324 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.675 0.324 0.000
T43.6 Psychostimulants with abuse potential
0.675 0.324 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.675 0.324 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.675 0.324 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.675 0.324 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.675 0.325 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.674 0.326 0.000
E40-E46 Malnutrition
0.674 0.326 0.000
M50.0 Cervical disk disorder with myelopathy
0.673 0.326 0.000
T40.2 Other opioids
0.673 0.327 0.000
R45.1 Restlessness and agitation
0.672 0.328 0.000
K61.0 Anal abscess
0.671 0.329 0.000
N60 Benign mammary dysplasia
0.671 0.329 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.670 0.329 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.670 0.329 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.669 0.331 0.000
M47.8 Other spondylosis
0.668 0.332 0.000
M79.66 Pain in limb (Lower leg)
0.667 0.333 0.000
M54.59 Low back pain (Site unspecified)
0.667 0.333 0.000
K12 Stomatitis and related lesions
0.667 0.333 0.000
K10 Other diseases of jaws
0.667 0.333 0.000
K09 Cysts of oral region, not elsewhere classified
0.667 0.333 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.667 0.333 0.000
K03 Other diseases of hard tissues of teeth
0.667 0.333 0.000
K00 Disorders of tooth development and eruption
0.667 0.333 0.000
K56.4 Other impaction of intestine
0.666 0.334 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.666 0.334 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.666 0.334 0.000
R04.1 Haemorrhage from throat
0.666 0.334 0.000
M47.9 Spondylosis, unspecified
0.666 0.334 0.000
S82.1 Fracture of upper end of tibia
0.664 0.336 0.000
R07.1 Chest pain on breathing
0.664 0.336 0.000
M40-M43 Deforming dorsopathies
0.664 0.336 0.000
K81.8 Other cholecystitis
0.663 0.337 0.000
R46 Symptoms and signs involving appearance and behaviour
0.663 0.337 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.663 0.337 0.000
R43 Disturbances of smell and taste
0.663 0.337 0.000
M25.53 Pain in joint (Forearm)
0.663 0.337 0.000
K13 Other diseases of lip and oral mucosa
0.662 0.337 0.000
N19 Unspecified renal failure
0.662 0.338 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.662 0.338 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.662 0.338 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.662 0.338 0.000
M05-M14 Inflammatory polyarthropathies
0.662 0.338 0.000
M48.0 Spinal stenosis
0.661 0.339 0.000
M54.36 Sciatica (Lumbar region)
0.661 0.339 0.000
R06 Abnormalities of breathing
0.661 0.339 0.000
O72.1 Other immediate postpartum haemorrhage
0.661 0.339 0.000
S82.8 Fractures of other parts of lower leg
0.660 0.339 0.000
H04 Disorders of lachrymal system
0.660 0.340 0.000
O48 Prolonged pregnancy
0.660 0.340 0.000
T42.4 Benzodiazepines
0.660 0.340 0.000
F10.3 Withdrawal state
0.659 0.341 0.000
M79.62 Pain in limb (Upper arm)
0.659 0.341 0.000
R68 Other general symptoms and signs
0.658 0.341 0.000
S82.9 Fracture of lower leg, part unspecified
0.658 0.342 0.000
S82.7 Multiple fractures of lower leg
0.658 0.342 0.000
S82.0 Fracture of patella
0.658 0.342 0.000
K56.0 Paralytic ileus
0.657 0.343 0.000
R59.0 Localised enlarged lymph nodes
0.657 0.343 0.000
Q60-Q64 Congenital malformations of the urinary system
0.656 0.344 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.656 0.344 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.656 0.344 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.656 0.344 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.656 0.344 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.656 0.344 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.656 0.344 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.656 0.344 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.656 0.344 0.000
K11.2 Sialoadenitis
0.656 0.344 0.000
K86.1 Other chronic pancreatitis
0.656 0.344 0.000
C15 Malignant neoplasm of oesophagus
0.656 0.344 0.000
K04.5 Chronic apical periodontitis
0.655 0.345 0.000
K82.4 Cholesterolosis of gallbladder
0.655 0.345 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.654 0.346 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.653 0.347 0.000
R62 Lack of expected normal physiological development
0.653 0.347 0.000
R57 Shock, not elsewhere classified
0.653 0.347 0.000
R64 Cachexia
0.653 0.347 0.000
R58 Haemorrhage, not elsewhere classified
0.653 0.347 0.000
R54 Senility
0.653 0.347 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.653 0.347 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.653 0.347 0.000
T39.4 Antirheumatics, not elsewhere classified
0.653 0.347 0.000
T39.2 Pyrazolone derivatives
0.653 0.347 0.000
E53.8 Deficiency of other specified B group vitamins
0.653 0.347 0.000
M49 Spondylopathies in diseases classified elsewhere
0.652 0.348 0.000
M46 Other inflammatory spondylopathies
0.652 0.348 0.000
H02.3 Blepharochalasis
0.652 0.348 0.000
M50.3 Other cervical disk degeneration
0.651 0.349 0.000
R52.2 Other chronic pain
0.651 0.349 0.000
M22 Disorders of patella
0.651 0.349 0.000
H55 Nystagmus and other irregular eye movements
0.650 0.350 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.649 0.351 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.649 0.351 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.649 0.351 0.000
M34 Systemic sclerosis
0.649 0.351 0.000
M33 Dermatopolymyositis
0.649 0.351 0.000
M32 Systemic lupus erythematosus
0.649 0.351 0.000
M30 Polyarteritis nodosa and related conditions
0.649 0.351 0.000
M24 Other specific joint derangements
0.649 0.351 0.000
X60-X84 Intentional self-harm
0.649 0.351 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.647 0.352 0.000
O70.9 Perineal laceration during delivery, unspecified
0.647 0.353 0.000
O70.3 Fourth degree perineal laceration during delivery
0.647 0.353 0.000
O70.2 Third degree perineal laceration during delivery
0.647 0.353 0.000
K11.5 Sialolithiasis
0.647 0.353 0.000
K60 Fissure and fistula of anal and rectal regions
0.646 0.354 0.000
D50-D53 Nutritional anaemias
0.644 0.356 0.000
Z72.0 Tobacco use
0.644 0.356 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.643 0.357 0.000
R50.9 Fever, unspecified
0.642 0.358 0.000
M25.54 Pain in joint (Hand)
0.642 0.358 0.000
N18.8 Other chronic renal failure
0.641 0.358 0.000
N18.5 Chronic kidney disease, stage 5
0.641 0.358 0.000
N18.2 Chronic kidney disease, stage 2
0.641 0.358 0.000
N18.1 Chronic kidney disease, stage 1
0.641 0.358 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.641 0.359 0.000
K56.1 Intussusception
0.640 0.360 0.000
D80-D89 Certain disorders involving the immune mechanism
0.640 0.360 0.000
R59.1 Generalised enlarged lymph nodes
0.640 0.360 0.000
M45 Ankylosing spondylitis
0.639 0.361 0.000
R55 Syncope and collapse
0.638 0.362 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.637 0.362 0.000
E78.0 Pure hypercholesterolaemia
0.637 0.363 0.000
K83.9 Disease of biliary tract, unspecified
0.637 0.363 0.000
K83.5 Biliary cyst
0.637 0.363 0.000
K83.4 Spasm of sphincter of Oddi
0.637 0.363 0.000
K83.3 Fistula of bile duct
0.637 0.363 0.000
K83.2 Perforation of bile duct
0.637 0.363 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.636 0.364 0.000
G90-G99 Other disorders of the nervous system
0.635 0.365 0.000
M50.9 Cervical disk disorder, unspecified
0.634 0.366 0.000
M50.8 Other cervical disk disorders
0.634 0.366 0.000
D55-D59 Haemolytic anaemias
0.634 0.366 0.000
M79.9 Soft tissue disorder, unspecified
0.634 0.366 0.000
M79.5 Residual foreign body in soft tissue
0.634 0.366 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.634 0.366 0.000
M79.3 Panniculitis, unspecified
0.634 0.366 0.000
M79.2 Neuralgia and neuritis, unspecified
0.634 0.366 0.000
M79.1 Myalgia
0.634 0.366 0.000
R20 Disturbances of skin sensation
0.634 0.366 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.633 0.367 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.632 0.367 0.000
M25.57 Pain in joint (Ankle and foot)
0.632 0.368 0.000
K05 Gingivitis and periodontal diseases
0.631 0.369 0.000
K82.3 Fistula of gallbladder
0.630 0.370 0.000
K82.2 Perforation of gallbladder
0.630 0.370 0.000
K82.1 Hydrops of gallbladder
0.630 0.370 0.000
K82.0 Obstruction of gallbladder
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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