TreeWAS – Variant ID: rs4873403

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.406	0.594
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.380	0.620
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.375	0.625
Chapter IX Diseases of the circulatory system	0.369	0.631
Chapter XX External causes of morbidity and mortality	0.363	0.637
Chapter XI Diseases of the digestive system	0.350	0.650
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.348	0.652
Chapter XIV Diseases of the genitourinary system	0.348	0.652
Chapter VI Diseases of the nervous system	0.345	0.655
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.331	0.669
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.330	0.670
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.328	0.672
K50-K52 Noninfective enteritis and colitis	0.326	0.674
R50-R69 General symptoms and signs	0.325	0.675
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.320	0.680
Chapter IV Endocrine, nutritional and metabolic diseases	0.316	0.683
Chapter II Neoplasms	0.313	0.687
N80-N98 Noninflammatory disorders of female genital tract	0.313	0.687
R30-R39 Symptoms and signs involving the urinary system	0.312	0.688
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.309	0.691
Chapter I Certain infectious and parasitic diseases	0.308	0.691
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.307	0.692
Chapter VII Diseases of the eye and adnexa	0.306	0.694
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.301	0.699
T81 Complications of procedures, not elsewhere classified	0.299	0.701
G50-G59 Nerve, nerve root and plexus disorders	0.299	0.701
Chapter XII Diseases of the skin and subcutaneous tissue	0.299	0.701
K52 Other non-infective gastro-enteritis and colitis	0.298	0.702
I20-I25 Ischaemic heart diseases	0.296	0.704
Chapter VIII Diseases of the ear and mastoid process	0.294	0.705
Chapter XXII Codes for special purposes	0.291	0.709
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.291	0.709
Chapter XVI Certain conditions originating in the perinatal period	0.291	0.709
Chapter XV Pregnancy, childbirth and the puerperium	0.291	0.709
I30-I52 Other forms of heart disease	0.290	0.710
I84 Haemorrhoids	0.289	0.711
S60-S69 Injuries to the wrist and hand	0.283	0.717
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.283	0.717
T84.0 Mechanical complication of internal joint prosthesis	0.281	0.718
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.279	0.720
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.278	0.721
R11 Nausea and vomiting	0.275	0.725
N95 Menopausal and other perimenopausal disorders	0.273	0.727
R95-R99 Ill-defined and unknown causes of mortality	0.272	0.727
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.272	0.727
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.272	0.727
R47-R49 Symptoms and signs involving speech and voice	0.272	0.727
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.272	0.727
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.272	0.727
S50-S59 Injuries to the elbow and forearm	0.272	0.728
Chapter V Mental and behavioural disorders	0.270	0.730
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.270	0.730
R19 Other symptoms and signs involving the digestive system and abdomen	0.270	0.730
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.269	0.731
T79-T79 Certain early complications of trauma	0.269	0.731
T66-T78 Other and unspecified effects of external causes	0.269	0.731
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.269	0.731
T36-T50 Poisoning by drugs, medicaments and biological substances	0.269	0.731
T33-T35 Frostbite	0.269	0.731
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.269	0.731
T26-T28 Burns and corrosions confined to eye and internal organs	0.269	0.731
T20-T25 Burns and corrosions of external body surface, specified by site	0.269	0.731
T15-T19 Effects of foreign body entering through natural orifice	0.269	0.731
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.269	0.731
T00-T07 Injuries involving multiple body regions	0.269	0.731
S90-S99 Injuries to the ankle and foot	0.269	0.731
S80-S89 Injuries to the knee and lower leg	0.269	0.731
S70-S79 Injuries to the hip and thigh	0.269	0.731
S40-S49 Injuries to the shoulder and upper arm	0.269	0.731
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.269	0.731
S20-S29 Injuries to the thorax	0.269	0.731
S10-S19 Injuries to the neck	0.269	0.731
S00-S09 Injuries to the head	0.269	0.731
K51 Ulcerative colitis	0.267	0.733
I95-I99 Other and unspecified disorders of the circulatory system	0.265	0.735
I70-I79 Diseases of arteries, arterioles and capillaries	0.265	0.735
I60-I69 Cerebrovascular diseases	0.265	0.735
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.265	0.735
I05-I09 Chronic rheumatic heart diseases	0.265	0.735
I00-I02 Acute rheumatic fever	0.265	0.735
W00-W19 Falls	0.265	0.735
Y83.1 Surgical operation with implant of artificial internal device	0.263	0.737
N70-N77 Inflammatory diseases of female pelvic organs	0.262	0.738
Y83.6 Removal of other organ (partial) (total)	0.262	0.738
N30-N39 Other diseases of urinary system	0.261	0.739
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.260	0.740
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.260	0.740
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.260	0.740
Y60-Y69 Misadventures to patients during surgical and medical care	0.260	0.740
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.260	0.740
Y35-Y36 Legal intervention and operations of war	0.260	0.740
Y10-Y34 Event of undetermined intent	0.260	0.740
Y00-Y09 Assault	0.260	0.740
X85-X99 Assault	0.260	0.740
X60-X84 Intentional self-harm	0.260	0.740
X58-X59 Accidental exposure to other and unspecified factors	0.260	0.740
X50-X57 Overexertion, travel and privation	0.260	0.740
X40-X49 Accidental poisoning by and exposure to noxious substances	0.260	0.740
X30-X39 Exposure to forces of nature	0.260	0.740
X20-X29 Contact with venomous animals and plants	0.260	0.740
X10-X19 Contact with heat and hot substances	0.260	0.740
X00-X09 Exposure to smoke, fire and flames	0.260	0.740
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.260	0.740
W75-W84 Other accidental threats to breathing	0.260	0.740
W65-W74 Accidental drowning and submersion	0.260	0.740
W50-W64 Exposure to animate mechanical forces	0.260	0.740
W20-W49 Exposure to inanimate mechanical forces	0.260	0.740
V98-V99 Other and unspecified transport accidents	0.260	0.740
V95-V97 Air and space transport accidents	0.260	0.740
V90-V94 Water transport accidents	0.260	0.740
V80-V89 Other land transport accidents	0.260	0.740
V70-V79 Bus occupant injured in transport accident	0.260	0.740
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.260	0.740
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.260	0.740
V40-V49 Car occupant injured in transport accident	0.260	0.740
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.260	0.740
V20-V29 Motorcycle rider injured in transport accident	0.260	0.740
V10-V19 Pedal cyclist injured in transport accident	0.260	0.740
V01-V09 Pedestrian injured in transport accident	0.260	0.740
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.260	0.740
I83 Varicose veins of lower extremities	0.259	0.741
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.258	0.742
R13 Dysphagia	0.258	0.742
G56 Mononeuropathies of upper limb	0.257	0.742
Chapter X Diseases of the respiratory system	0.257	0.743
K65-K67 Diseases of peritoneum	0.255	0.745
R50 Fever of unknown origin	0.255	0.745
R63 Symptoms and signs concerning food and fluid intake	0.253	0.747
G40-G47 Episodic and paroxysmal disorders	0.253	0.747
R51 Headache	0.253	0.747
K40-K46 Hernia	0.252	0.748
K90-K93 Other diseases of the digestive system	0.251	0.749
K70-K77 Diseases of liver	0.251	0.749
K35-K38 Diseases of appendix	0.251	0.749
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.251	0.749
D60-D64 Aplastic and other anaemias	0.251	0.749
T88 Other complications of surgical and medical care, not elsewhere classified	0.250	0.750
T87 Complications peculiar to reattachment and amputation	0.250	0.750
T86 Failure and rejection of transplanted organs and tissues	0.250	0.750
T85 Complications of other internal prosthetic devices, implants and grafts	0.250	0.750
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.250	0.750
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.250	0.750
T80 Complications following infusion, transfusion and therapeutic injection	0.250	0.750
N84 Polyp of female genital tract	0.249	0.751
N99-N99 Other disorders of the genitourinary system	0.249	0.751
N60-N64 Disorders of breast	0.249	0.751
N25-N29 Other disorders of kidney and ureter	0.249	0.751
N20-N23 Urolithiasis	0.249	0.751
N17-N19 Renal failure	0.249	0.751
N10-N16 Renal tubulo-interstitial diseases	0.249	0.751
N00-N08 Glomerular diseases	0.249	0.751
E70-E90 Metabolic disorders	0.248	0.752
R32 Unspecified urinary incontinence	0.248	0.752
R31 Unspecified haematuria	0.248	0.752
G90-G99 Other disorders of the nervous system	0.247	0.752
G80-G83 Cerebral palsy and other paralytic syndromes	0.247	0.752
G70-G73 Diseases of myoneural junction and muscle	0.247	0.752
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.247	0.752
G35-G37 Demyelinating diseases of the central nervous system	0.247	0.752
G30-G32 Other degenerative diseases of the nervous system	0.247	0.752
G20-G26 Extrapyramidal and movement disorders	0.247	0.752
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.247	0.752
G00-G09 Inflammatory diseases of the central nervous system	0.247	0.752
Y83.8 Other surgical procedures	0.246	0.753
I84.6 Residual haemorrhoidal skin tags	0.246	0.754
R55 Syncope and collapse	0.245	0.755
N95.0 Postmenopausal bleeding	0.244	0.756
C15-C26 Malignant neoplasms of digestive organs	0.244	0.756
T81.3 Disruption of operation wound, not elsewhere classified	0.243	0.757
I10-I15 Hypertensive diseases	0.243	0.757
D10-D36 Benign neoplasms	0.242	0.758
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.241	0.759
R53 Malaise and fatigue	0.241	0.759
D50-D53 Nutritional anaemias	0.240	0.760
E00-E07 Disorders of thyroid gland	0.238	0.762
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.237	0.762
R18 Ascites	0.237	0.762
R17 Unspecified jaundice	0.237	0.762
R15 Faecal incontinence	0.237	0.762
R14 Flatulence and related conditions	0.237	0.762
R12 Heartburn	0.237	0.762
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.237	0.763
A00-A09 Intestinal infectious diseases	0.236	0.764
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.235	0.765
I88 Nonspecific lymphadenitis	0.235	0.765
I87 Other disorders of veins	0.235	0.765
I86 Varicose veins of other sites	0.235	0.765
I85 Oesophageal varices	0.235	0.765
I82 Other venous embolism and thrombosis	0.235	0.765
I80 Phlebitis and thrombophlebitis	0.235	0.765
I81 Portal vein thrombosis	0.235	0.765
M05-M14 Inflammatory polyarthropathies	0.235	0.765
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.235	0.765
M50-M54 Other dorsopathies	0.234	0.766
H25-H28 Disorders of lens	0.234	0.766
K50 Crohn's disease [regional enteritis]	0.234	0.766
I51 Complications and ill-defined descriptions of heart disease	0.234	0.766
I20 Angina pectoris	0.233	0.767
K55-K64 Other diseases of intestines	0.233	0.767
R68 Other general symptoms and signs	0.233	0.767
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.233	0.767
R62 Lack of expected normal physiological development	0.233	0.767
R61 Hyperhidrosis	0.233	0.767
R60 Oedema, not elsewhere classified	0.233	0.767
R59 Enlarged lymph nodes	0.233	0.767
R57 Shock, not elsewhere classified	0.233	0.767
R56 Convulsions, not elsewhere classified	0.233	0.767
R52 Pain, not elsewhere classified	0.233	0.767
R64 Cachexia	0.233	0.767
R58 Haemorrhage, not elsewhere classified	0.233	0.767
R54 Senility	0.233	0.767
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.232	0.768
T81.4 Infection following a procedure, not elsewhere classified	0.231	0.769
R39 Other symptoms and signs involving the urinary system	0.230	0.769
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.230	0.770
D80-D89 Certain disorders involving the immune mechanism	0.230	0.770
D70-D77 Other diseases of blood and blood-forming organs	0.230	0.770
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.230	0.770
D55-D59 Haemolytic anaemias	0.230	0.770
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.229	0.770
M20-M25 Other joint disorders	0.229	0.771
K80 Cholelithiasis	0.229	0.771
E10-E14 Diabetes mellitus	0.228	0.772
G56.0 Carpal tunnel syndrome	0.228	0.772
E50-E64 Other nutritional deficiencies	0.227	0.773
E40-E46 Malnutrition	0.227	0.773
E20-E35 Disorders of other endocrine glands	0.227	0.773
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.227	0.773
N81 Female genital prolapse	0.227	0.773
I25 Chronic ischaemic heart disease	0.226	0.774
C43-C44 Melanoma and other malignant neoplasms of skin	0.226	0.774
R19.4 Change in bowel habit	0.225	0.774
A30-A49 Other bacterial diseases	0.225	0.775
K51.9 Ulcerative colitis, unspecified	0.225	0.775
N98 Complications associated with artificial fertilisation	0.224	0.776
N97 Female infertility	0.224	0.776
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.224	0.776
N93 Other abnormal uterine and vaginal bleeding	0.224	0.776
N91 Absent, scanty and rare menstruation	0.224	0.776
N90 Other noninflammatory disorders of vulva and perineum	0.224	0.776
N89 Other noninflammatory disorders of vagina	0.224	0.776
N88 Other noninflammatory disorders of cervix uteri	0.224	0.776
N87 Dysplasia of cervix uteri	0.224	0.776
N85 Other noninflammatory disorders of uterus, except cervix	0.224	0.776
N82 Fistulae involving female genital tract	0.224	0.776
N80 Endometriosis	0.224	0.776
N96 Habitual aborter	0.224	0.776
N86 Erosion and ectropion of cervix uteri	0.224	0.776
D37-D48 Neoplasms of uncertain or unknown behaviour	0.224	0.776
D00-D09 In situ neoplasms	0.224	0.776
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.224	0.776
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.224	0.776
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.224	0.776
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.224	0.776
C64-C68 Malignant neoplasms of urinary tract	0.224	0.776
C51-C58 Malignant neoplasms of female genital organs	0.224	0.776
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.224	0.776
C40-C41 Malignant neoplasms of bone and articular cartilage	0.224	0.776
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.224	0.776
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.224	0.776
R30 Pain associated with micturition	0.224	0.776
R36 Urethral discharge	0.224	0.776
R35 Polyuria	0.224	0.776
R34 Anuria and oliguria	0.224	0.776
I84.9 Unspecified haemorrhoids without complication	0.224	0.776
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.222	0.778
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.222	0.778
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.222	0.778
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.222	0.778
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.222	0.778
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.222	0.778
T84.3 Mechanical complication of other bone devices, implants and grafts	0.222	0.778
T84.2 Mechanical complication of internal fixation device of other bones	0.222	0.778
T84.1 Mechanical complication of internal fixation device of bones of limb	0.222	0.778
B99-B99 Other infectious diseases	0.221	0.779
B90-B94 Sequelae of infectious and parasitic diseases	0.221	0.779
B85-B89 Pediculosis, acariasis and other infestations	0.221	0.779
B65-B83 Helminthiases	0.221	0.779
B50-B64 Protozoal diseases	0.221	0.779
B35-B49 Mycoses	0.221	0.779
B25-B34 Other viral diseases	0.221	0.779
B20-B24 Human immunodeficiency virus [HIV] disease	0.221	0.779
B15-B19 Viral hepatitis	0.221	0.779
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.221	0.779
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.221	0.779
A80-A89 Viral infections of the central nervous system	0.221	0.779
A75-A79 Rickettsioses	0.221	0.779
A70-A74 Other diseases caused by chlamydiae	0.221	0.779
A65-A69 Other spirochaetal diseases	0.221	0.779
A50-A64 Infections with a predominantly sexual mode of transmission	0.221	0.779
A20-A28 Certain zoonotic bacterial diseases	0.221	0.779
A15-A19 Tuberculosis	0.221	0.779
M45-M49 Spondylopathies	0.221	0.779
B95-B98 Bacterial, viral and other infectious agents	0.221	0.779
I84.2 Internal haemorrhoids without complication	0.221	0.779
Y83.9 Surgical procedure, unspecified	0.221	0.779
Y83.5 Amputation of limb(s)	0.221	0.779
Y83.4 Other reconstructive surgery	0.221	0.779
Y83.3 Surgical operation with formation of external stoma	0.221	0.779
Y83.2 Surgical operation with anastomosis, bypass or graft	0.221	0.779
Y83.0 Surgical operation with transplant of whole organ	0.221	0.779
E65-E68 Obesity and other hyperalimentation	0.220	0.780
H55-H59 Other disorders of eye and adnexa	0.219	0.781
H53-H54 Visual disturbances and blindness	0.219	0.781
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.219	0.781
H46-H48 Disorders of optic nerve and visual pathways	0.219	0.781
H43-H45 Disorders of vitreous body and globe	0.219	0.781
H40-H42 Glaucoma	0.219	0.781
H30-H36 Disorders of choroid and retina	0.219	0.781
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.219	0.781
H10-H13 Disorders of conjunctiva	0.219	0.781
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.219	0.781
S61 Open wound of wrist and hand	0.218	0.782
C50-C50 Malignant neoplasm of breast	0.218	0.782
R10 Abdominal and pelvic pain	0.217	0.783
R69 Unknown and unspecified causes of morbidity	0.217	0.783
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.216	0.784
M91-M94 Chondropathies	0.216	0.784
M86-M90 Other osteopathies	0.216	0.784
M80-M85 Disorders of bone density and structure	0.216	0.784
M65-M68 Disorders of synovium and tendon	0.216	0.784
M60-M63 Disorders of muscles	0.216	0.784
M40-M43 Deforming dorsopathies	0.216	0.784
M00-M03 Infectious arthropathies	0.216	0.784
H90-H95 Other disorders of ear	0.215	0.785
T81.9 Unspecified complication of procedure	0.215	0.785
T81.8 Other complications of procedures, not elsewhere classified	0.215	0.785
T81.7 Vascular complications following a procedure, not elsewhere classified	0.215	0.785
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.215	0.785
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.215	0.785
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.215	0.785
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.215	0.785
G59 Mononeuropathy in diseases classified elsewhere	0.214	0.785
G58 Other mononeuropathies	0.214	0.785
G57 Mononeuropathies of lower limb	0.214	0.785
G54 Nerve root and plexus disorders	0.214	0.785
G53 Cranial nerve disorders in diseases classified elsewhere	0.214	0.785
G52 Disorders of other cranial nerves	0.214	0.785
G51 Facial nerve disorders	0.214	0.785
G50 Disorders of trigeminal nerve	0.214	0.785
L60-L75 Disorders of skin appendages	0.214	0.785
L50-L54 Urticaria and erythema	0.214	0.785
L40-L45 Papulosquamous disorders	0.214	0.785
L20-L30 Dermatitis and eczema	0.214	0.785
L10-L14 Bullous disorders	0.214	0.785
N92 Excessive, frequent and irregular menstruation	0.214	0.785
K52.8 Other specified non-infective gastro-enteritis and colitis	0.214	0.786
K52.3 Indeterminate colitis	0.214	0.786
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.214	0.786
K52.1 Toxic gastro-enteritis and colitis	0.214	0.786
K52.0 Gastro-enteritis and colitis due to radiation	0.214	0.786
R33 Retention of urine	0.213	0.786
R94 Abnormal results of function studies	0.213	0.787
L00-L08 Infections of the skin and subcutaneous tissue	0.212	0.787
I24 Other acute ischaemic heart diseases	0.212	0.788
I23 Certain current complications following acute myocardial infarction	0.212	0.788
I22 Subsequent myocardial infarction	0.212	0.788
H80-H83 Diseases of inner ear	0.211	0.789
H65-H75 Diseases of middle ear and mastoid	0.211	0.789
H60-H62 Diseases of external ear	0.211	0.789
I21 Acute myocardial infarction	0.211	0.789
Chapter XXI Factors influencing health status and contact with health services	0.210	0.790
N39 Other disorders of urinary system	0.210	0.790
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.209	0.791
M70-M79 Other soft tissue disorders	0.209	0.791
O94-O99 Other obstetric conditions, not elsewhere classified	0.209	0.791
O85-O92 Complications predominantly related to the puerperium	0.209	0.791
O80-O84 Delivery	0.209	0.791
O60-O75 Complications of labour and delivery	0.209	0.791
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.209	0.791
O20-O29 Other maternal disorders predominantly related to pregnancy	0.209	0.791
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.209	0.791
O00-O08 Pregnancy with abortive outcome	0.209	0.791
P90-P96 Other disorders originating in the perinatal period	0.209	0.791
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.209	0.791
P75-P78 Digestive system disorders of fetus and newborn	0.209	0.791
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.209	0.791
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.209	0.791
P35-P39 Infections specific to the perinatal period	0.209	0.791
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.209	0.791
P10-P15 Birth trauma	0.209	0.791
P05-P08 Disorders related to length of gestation and fetal growth	0.209	0.791
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.209	0.791
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.209	0.791
Q80-Q89 Other congenital malformations	0.209	0.791
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.209	0.791
Q60-Q64 Congenital malformations of the urinary system	0.209	0.791
Q50-Q56 Congenital malformations of genital organs	0.209	0.791
Q38-Q45 Other congenital malformations of the digestive system	0.209	0.791
Q35-Q37 Cleft lip and cleft palate	0.209	0.791
Q30-Q34 Congenital malformations of the respiratory system	0.209	0.791
Q20-Q28 Congenital malformations of the circulatory system	0.209	0.791
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.209	0.791
Q00-Q07 Congenital malformations of the nervous system	0.209	0.791
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.209	0.791
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.209	0.791
L80-L99 Other disorders of the skin and subcutaneous tissue	0.208	0.792
I52 Other heart disorders in diseases classified elsewhere	0.208	0.792
I50 Heart failure	0.208	0.792
I49 Other cardiac arrhythmias	0.208	0.792
I48 Atrial fibrillation and flutter	0.208	0.792
I47 Paroxysmal tachycardia	0.208	0.792
I46 Cardiac arrest	0.208	0.792
I45 Other conduction disorders	0.208	0.792
I44 Atrioventricular and left bundle-branch block	0.208	0.792
I43 Cardiomyopathy in diseases classified elsewhere	0.208	0.792
I42 Cardiomyopathy	0.208	0.792
I41 Myocarditis in diseases classified elsewhere	0.208	0.792
I40 Acute myocarditis	0.208	0.792
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.208	0.792
I37 Pulmonary valve disorders	0.208	0.792
I36 Nonrheumatic tricuspid valve disorders	0.208	0.792
I35 Nonrheumatic aortic valve disorders	0.208	0.792
I34 Nonrheumatic mitral valve disorders	0.208	0.792
I33 Acute and subacute endocarditis	0.208	0.792
I32 Pericarditis in diseases classified elsewhere	0.208	0.792
I31 Other diseases of pericardium	0.208	0.792
I30 Acute pericarditis	0.208	0.792
I38 Endocarditis, valve unspecified	0.208	0.792
I84.8 Unspecified haemorrhoids with other complications	0.207	0.793
I84.7 Unspecified thrombosed haemorrhoids	0.207	0.793
I84.5 External haemorrhoids without complication	0.207	0.793
I84.4 External haemorrhoids with other complications	0.207	0.793
I84.3 External thrombosed haemorrhoids	0.207	0.793
I84.1 Internal haemorrhoids with other complications	0.207	0.793
I84.0 Internal thrombosed haemorrhoids	0.207	0.793
E87 Other disorders of fluid, electrolyte and acid-base balance	0.207	0.793
C60-C63 Malignant neoplasms of male genital organs	0.205	0.794
R50.9 Fever, unspecified	0.205	0.794
S69 Other and unspecified injuries of wrist and hand	0.203	0.797
S68 Traumatic amputation of wrist and hand	0.203	0.797
S67 Crushing injury of wrist and hand	0.203	0.797
S66 Injury of muscle and tendon at wrist and hand level	0.203	0.797
S65 Injury of blood vessels at wrist and hand level	0.203	0.797
S64 Injury of nerves at wrist and hand level	0.203	0.797
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.203	0.797
S62 Fracture at wrist and hand level	0.203	0.797
S60 Superficial injury of wrist and hand	0.203	0.797
R93 Abnormal findings on diagnostic imaging of other body structures	0.203	0.797
R90 Abnormal findings on diagnostic imaging of central nervous system	0.203	0.797
R92 Abnormal findings on diagnostic imaging of breast	0.203	0.797
R91 Abnormal findings on diagnostic imaging of lung	0.203	0.797
R63.4 Abnormal weight loss	0.202	0.798
D64 Other anaemias	0.201	0.799
N73 Other female pelvic inflammatory diseases	0.201	0.799
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.200	0.799
K86 Other diseases of pancreas	0.200	0.799
K85 Acute pancreatitis	0.200	0.799
K83 Other diseases of biliary tract	0.200	0.799
K82 Other diseases of gallbladder	0.200	0.799
K81 Cholecystitis	0.200	0.799
F40-F48 Neurotic, stress-related and somatoform disorders	0.200	0.800
I20.9 Angina pectoris, unspecified	0.199	0.801
J95-J99 Other diseases of the respiratory system	0.198	0.801
S52 Fracture of forearm	0.198	0.801
G40 Epilepsy	0.197	0.803
N84.1 Polyp of cervix uteri	0.196	0.804
N95.9 Menopausal and perimenopausal disorder, unspecified	0.196	0.804
N95.8 Other specified menopausal and perimenopausal disorders	0.196	0.804
N95.3 States associated with artificial menopause	0.196	0.804
N95.2 Postmenopausal atrophic vaginitis	0.196	0.804
N95.1 Menopausal and female climacteric states	0.196	0.804
R23 Other skin changes	0.195	0.804
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.195	0.804
R20 Disturbances of skin sensation	0.195	0.804
R21 Rash and other nonspecific skin eruption	0.195	0.804
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.195	0.804
R27 Other lack of coordination	0.195	0.804
R26 Abnormalities of gait and mobility	0.195	0.804
R25 Abnormal involuntary movements	0.195	0.804
R49 Voice disturbances	0.195	0.804
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.195	0.804
R47 Speech disturbances, not elsewhere classified	0.195	0.804
R82 Other abnormal findings in urine	0.195	0.804
R81 Glycosuria	0.195	0.804
R80 Isolated proteinuria	0.195	0.804
R89 Abnormal findings in specimens from other organs, systems and tissues	0.195	0.804
R87 Abnormal findings in specimens from female genital organs	0.195	0.804
R86 Abnormal findings in specimens from male genital organs	0.195	0.804
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.195	0.804
R84 Abnormal findings in specimens from respiratory organs and thorax	0.195	0.804
R83 Abnormal findings in cerebrospinal fluid	0.195	0.804
R96 Other sudden death, cause unknown	0.195	0.804
R95 Sudden infant death syndrome	0.195	0.804
R99 Other ill-defined and unspecified causes of mortality	0.195	0.804
R98 Unattended death	0.195	0.804
N40-N51 Diseases of male genital organs	0.195	0.805
S59 Other and unspecified injuries of forearm	0.195	0.805
S58 Traumatic amputation of forearm	0.195	0.805
S57 Crushing injury of forearm	0.195	0.805
S56 Injury of muscle and tendon at forearm level	0.195	0.805
S55 Injury of blood vessels at forearm level	0.195	0.805
S54 Injury of nerves at forearm level	0.195	0.805
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.195	0.805
S51 Open wound of forearm	0.195	0.805
S50 Superficial injury of forearm	0.195	0.805
R04 Haemorrhage from respiratory passages	0.195	0.805
W19 Unspecified fall	0.194	0.805
C18 Malignant neoplasm of colon	0.194	0.805
F99-F99 Unspecified mental disorder	0.194	0.806

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations