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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117531883
log Bayes Factor = 20.9443
Chromosome 8   position 8,309,054  (GRCh37) Explore rs117531883 on Ensembl!
Variant rs117531883 is part of Cluster X0058

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
M54 Dorsalgia
0.995 0.005 0.000
Z96 Presence of other functional implants
0.992 0.008 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
Chapter II Neoplasms
0.990 0.010 0.000
M20-M25 Other joint disorders
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
K65-K67 Diseases of peritoneum
0.985 0.015 0.000
M70-M79 Other soft tissue disorders
0.982 0.018 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.980 0.020 0.000
Z96.6 Presence of orthopaedic joint implants
0.978 0.022 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.975 0.025 0.000
J30-J39 Other diseases of upper respiratory tract
0.969 0.031 0.000
K66 Other disorders of peritoneum
0.969 0.031 0.000
M25 Other joint disorders, not elsewhere classified
0.968 0.032 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.967 0.033 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.964 0.036 0.000
Z85 Personal history of malignant neoplasm
0.959 0.041 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.958 0.042 0.000
K66.0 Peritoneal adhesions
0.958 0.042 0.000
Chapter V Mental and behavioural disorders
0.956 0.044 0.000
M25.5 Pain in joint
0.955 0.045 0.000
M54.5 Low back pain
0.952 0.048 0.000
M05-M14 Inflammatory polyarthropathies
0.952 0.048 0.000
M45-M49 Spondylopathies
0.952 0.048 0.000
Chapter IX Diseases of the circulatory system
0.951 0.049 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.948 0.052 0.000
K70-K77 Diseases of liver
0.948 0.052 0.000
Chapter VII Diseases of the eye and adnexa
0.943 0.057 0.000
K22 Other diseases of oesophagus
0.936 0.064 0.000
C15-C26 Malignant neoplasms of digestive organs
0.936 0.064 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.936 0.064 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.935 0.065 0.000
G40-G47 Episodic and paroxysmal disorders
0.934 0.066 0.000
G56 Mononeuropathies of upper limb
0.931 0.069 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.927 0.073 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.924 0.076 0.000
M54.59 Low back pain (Site unspecified)
0.923 0.077 0.000
M54.3 Sciatica
0.917 0.083 0.000
Chapter XX External causes of morbidity and mortality
0.917 0.083 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.914 0.086 0.000
M54.9 Dorsalgia, unspecified
0.912 0.088 0.000
G56.0 Carpal tunnel syndrome
0.912 0.088 0.000
M47 Spondylosis
0.909 0.091 0.000
K29 Gastritis and duodenitis
0.908 0.092 0.000
Z98 Other postsurgical states
0.908 0.092 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.903 0.097 0.000
R30-R39 Symptoms and signs involving the urinary system
0.903 0.097 0.000
Z96.0 Presence of urogenital implants
0.902 0.098 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.901 0.099 0.000
D10-D36 Benign neoplasms
0.897 0.103 0.000
O60-O75 Complications of labour and delivery
0.894 0.106 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.893 0.107 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.891 0.109 0.000
M13 Other arthritis
0.890 0.110 0.000
R32 Unspecified urinary incontinence
0.889 0.111 0.000
D00-D09 In situ neoplasms
0.888 0.112 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.887 0.113 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.887 0.113 0.000
K29.6 Other gastritis
0.887 0.113 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.886 0.114 0.000
Z86 Personal history of certain other diseases
0.885 0.115 0.000
M47.9 Spondylosis, unspecified
0.881 0.119 0.000
C20 Malignant neoplasm of rectum
0.879 0.121 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.879 0.121 0.000
M79.6 Pain in limb
0.878 0.122 0.000
M50 Cervical disk disorders
0.878 0.122 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.875 0.125 0.000
H53-H54 Visual disturbances and blindness
0.874 0.126 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.870 0.130 0.000
J35 Chronic diseases of tonsils and adenoids
0.862 0.138 0.000
J33 Nasal polyp
0.862 0.138 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.860 0.140 0.000
E70-E90 Metabolic disorders
0.859 0.141 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.859 0.141 0.000
M79.8 Other specified soft tissue disorders
0.856 0.144 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.855 0.145 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.854 0.146 0.000
J32 Chronic sinusitis
0.852 0.148 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.851 0.149 0.000
M25.51 Pain in joint (Shoulder region)
0.850 0.150 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.846 0.154 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.844 0.156 0.000
M22 Disorders of patella
0.838 0.162 0.000
J90-J94 Other diseases of pleura
0.838 0.162 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.838 0.162 0.000
Z87 Personal history of other diseases and conditions
0.837 0.163 0.000
G30-G32 Other degenerative diseases of the nervous system
0.837 0.163 0.000
R20 Disturbances of skin sensation
0.837 0.163 0.000
M65-M68 Disorders of synovium and tendon
0.836 0.163 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.836 0.164 0.000
O48 Prolonged pregnancy
0.836 0.164 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.835 0.165 0.000
G43 Migraine
0.829 0.171 0.000
K65 Peritonitis
0.827 0.173 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.827 0.173 0.000
G90-G99 Other disorders of the nervous system
0.826 0.174 0.000
M40-M43 Deforming dorsopathies
0.825 0.175 0.000
M13.9 Arthritis, unspecified
0.825 0.175 0.000
M80-M85 Disorders of bone density and structure
0.824 0.176 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.823 0.177 0.000
M35 Other systemic involvement of connective tissue
0.823 0.177 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.823 0.177 0.000
O36 Maternal care for other known or suspected foetal problems
0.821 0.179 0.000
M06 Other rheumatoid arthritis
0.820 0.180 0.000
Chapter I Certain infectious and parasitic diseases
0.819 0.180 0.000
K40-K46 Hernia
0.819 0.181 0.000
K90-K93 Other diseases of the digestive system
0.817 0.183 0.000
M79.7 Fibromyalgia
0.817 0.183 0.000
F41 Other anxiety disorders
0.816 0.184 0.000
Z90.7 Acquired absence of genital organ(s)
0.816 0.184 0.000
K22.4 Dyskinesia of oesophagus
0.816 0.184 0.000
Z87.1 Personal history of diseases of the digestive system
0.815 0.185 0.000
Y43 Primarily systemic agents
0.811 0.189 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.810 0.190 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.810 0.190 0.000
C64-C68 Malignant neoplasms of urinary tract
0.808 0.192 0.000
L20-L30 Dermatitis and eczema
0.808 0.192 0.000
M25.56 Pain in joint (Lower leg)
0.808 0.192 0.000
H53 Visual disturbances
0.806 0.194 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.806 0.194 0.000
I30-I52 Other forms of heart disease
0.805 0.195 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.804 0.196 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.802 0.198 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.802 0.198 0.000
M54.39 Sciatica (Site unspecified)
0.801 0.199 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.800 0.200 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.797 0.203 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.797 0.203 0.000
J33.9 Nasal polyp, unspecified
0.797 0.203 0.000
O72 Postpartum haemorrhage
0.797 0.203 0.000
I05-I09 Chronic rheumatic heart diseases
0.795 0.205 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.793 0.207 0.000
K22.7 Barrett's oesophagus
0.792 0.208 0.000
M54.36 Sciatica (Lumbar region)
0.790 0.210 0.000
I85 Oesophageal varices
0.790 0.210 0.000
K70 Alcoholic liver disease
0.789 0.211 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.789 0.211 0.000
Z98.0 Intestinal bypass and anastomosis status
0.789 0.211 0.000
D05 Carcinoma in situ of breast
0.788 0.212 0.000
L81 Other disorders of pigmentation
0.788 0.212 0.000
C91 Lymphoid leukaemia
0.788 0.212 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.788 0.212 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.787 0.213 0.000
M79.0 Rheumatism, unspecified
0.787 0.213 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.785 0.215 0.000
K29.5 Chronic gastritis, unspecified
0.785 0.215 0.000
K74 Fibrosis and cirrhosis of liver
0.784 0.216 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.784 0.216 0.000
D60-D64 Aplastic and other anaemias
0.784 0.216 0.000
M91-M94 Chondropathies
0.784 0.216 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.783 0.217 0.000
M54.2 Cervicalgia
0.783 0.217 0.000
Z85.6 Personal history of leukaemia
0.783 0.217 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.782 0.218 0.000
K22.8 Other specified diseases of oesophagus
0.782 0.218 0.000
J00-J06 Acute upper respiratory infections
0.780 0.220 0.000
M21 Other acquired deformities of limbs
0.780 0.220 0.000
E00-E07 Disorders of thyroid gland
0.780 0.220 0.000
M50.2 Other cervical disk displacement
0.779 0.221 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.777 0.223 0.000
D23 Other benign neoplasms of skin
0.776 0.224 0.000
M24 Other specific joint derangements
0.776 0.224 0.000
C44 Other malignant neoplasms of skin
0.775 0.225 0.000
Z97 Presence of other devices
0.774 0.226 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.773 0.227 0.000
L82 Seborrhoeic keratosis
0.773 0.227 0.000
O44 Placenta praevia
0.772 0.228 0.000
J35.1 Hypertrophy of tonsils
0.772 0.228 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.770 0.230 0.000
M79.69 Pain in limb (Site unspecified)
0.770 0.230 0.000
Y43.3 Other antineoplastic drugs
0.769 0.231 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.768 0.232 0.000
K22.9 Disease of oesophagus, unspecified
0.767 0.233 0.000
R29.6 Tendency to fall, not elsewhere classified
0.767 0.233 0.000
K76 Other diseases of liver
0.766 0.234 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.766 0.234 0.000
M46 Other inflammatory spondylopathies
0.764 0.236 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.763 0.237 0.000
O32.1 Maternal care for breech presentation
0.763 0.237 0.000
Chapter VIII Diseases of the ear and mastoid process
0.761 0.239 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.759 0.241 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.759 0.241 0.000
M54.1 Radiculopathy
0.759 0.241 0.000
R39 Other symptoms and signs involving the urinary system
0.759 0.241 0.000
Z88.0 Personal history of allergy to penicillin
0.758 0.242 0.000
K72 Hepatic failure, not elsewhere classified
0.757 0.243 0.000
I81 Portal vein thrombosis
0.757 0.243 0.000
Z89 Acquired absence of limb
0.757 0.243 0.000
M25.54 Pain in joint (Hand)
0.756 0.243 0.000
Z98.1 Arthrodesis status
0.756 0.244 0.000
H25-H28 Disorders of lens
0.755 0.245 0.000
D22 Melanocytic naevi
0.754 0.246 0.000
K30 Dyspepsia
0.754 0.246 0.000
O80-O84 Delivery
0.752 0.247 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.752 0.248 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.750 0.250 0.000
J39 Other diseases of upper respiratory tract
0.748 0.252 0.000
M23 Internal derangement of knee
0.748 0.252 0.000
G43.9 Migraine, unspecified
0.747 0.252 0.000
K26 Duodenal ulcer
0.746 0.253 0.000
E87.2 Acidosis
0.746 0.254 0.000
G47 Sleep disorders
0.745 0.255 0.000
M25.57 Pain in joint (Ankle and foot)
0.744 0.256 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.744 0.256 0.000
Z99.3 Dependence on wheelchair
0.743 0.257 0.000
M75 Shoulder lesions
0.743 0.257 0.000
Z34 Supervision of normal pregnancy
0.742 0.258 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.742 0.258 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.742 0.258 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.741 0.259 0.000
Z33 Pregnant state, incidental
0.741 0.259 0.000
J09-J18 Influenza and pneumonia
0.740 0.260 0.000
I85.9 Oesophageal varices without bleeding
0.740 0.260 0.000
H55-H59 Other disorders of eye and adnexa
0.739 0.261 0.000
Z86.4 Personal history of psychoactive substance abuse
0.739 0.261 0.000
M79.5 Residual foreign body in soft tissue
0.738 0.262 0.000
M77 Other enthesopathies
0.737 0.262 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.737 0.263 0.000
K75 Other inflammatory liver diseases
0.737 0.263 0.000
M86-M90 Other osteopathies
0.736 0.263 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.735 0.265 0.000
O70 Perineal laceration during delivery
0.735 0.265 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.734 0.266 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.734 0.266 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.734 0.266 0.000
J30 Vasomotor and allergic rhinitis
0.731 0.269 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.731 0.269 0.000
A30-A49 Other bacterial diseases
0.729 0.271 0.000
Z39 Postpartum care and examination
0.729 0.271 0.000
K20 Oesophagitis
0.729 0.271 0.000
D16 Benign neoplasm of bone and articular cartilage
0.728 0.272 0.000
Z91.6 Personal history of other physical trauma
0.728 0.272 0.000
M47.2 Other spondylosis with radiculopathy
0.728 0.272 0.000
D64 Other anaemias
0.727 0.273 0.000
M06.9 Rheumatoid arthritis, unspecified
0.726 0.274 0.000
J90 Pleural effusion, not elsewhere classified
0.726 0.274 0.000
D27 Benign neoplasm of ovary
0.724 0.276 0.000
I49 Other cardiac arrhythmias
0.723 0.277 0.000
M54.56 Low back pain (Lumbar region)
0.722 0.278 0.000
Z91.5 Personal history of self-harm
0.721 0.279 0.000
K43 Ventral hernia
0.721 0.279 0.000
Z86.7 Personal history of diseases of the circulatory system
0.720 0.280 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.720 0.280 0.000
D34 Benign neoplasm of thyroid gland
0.720 0.280 0.000
M13.0 Polyarthritis, unspecified
0.719 0.281 0.000
M05 Seropositive rheumatoid arthritis
0.719 0.281 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.718 0.282 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.718 0.282 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
O30 Multiple gestation
0.717 0.283 0.000
M51 Other intervertebral disk disorders
0.716 0.283 0.000
M53 Other dorsopathies, not elsewhere classified
0.716 0.284 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.715 0.284 0.000
M84 Disorders of continuity of bone
0.714 0.286 0.000
G70-G73 Diseases of myoneural junction and muscle
0.714 0.286 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.286 0.000
I70 Atherosclerosis
0.714 0.286 0.000
M54.8 Other dorsalgia
0.713 0.286 0.000
M54.6 Pain in thoracic spine
0.713 0.286 0.000
M54.4 Lumbago with sciatica
0.713 0.286 0.000
M54.0 Panniculitis affecting regions of neck and back
0.713 0.286 0.000
Z90.8 Acquired absence of other organs
0.713 0.287 0.000
Z96.9 Presence of functional implant, unspecified
0.712 0.288 0.000
Z96.7 Presence of other bone and tendon implants
0.712 0.288 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.712 0.288 0.000
Z96.4 Presence of endocrine implants
0.712 0.288 0.000
Z96.3 Presence of artificial larynx
0.712 0.288 0.000
Z96.2 Presence of otological and audiological implants
0.712 0.288 0.000
J32.2 Chronic ethmoidal sinusitis
0.712 0.288 0.000
O85-O92 Complications predominantly related to the puerperium
0.711 0.288 0.000
Z88.5 Personal history of allergy to narcotic agent
0.710 0.290 0.000
Z83 Family history of other specific disorders
0.710 0.290 0.000
L81.9 Disorder of pigmentation, unspecified
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.710 0.290 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.710 0.290 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.709 0.291 0.000
M34 Systemic sclerosis
0.709 0.291 0.000
M33 Dermatopolymyositis
0.709 0.291 0.000
M32 Systemic lupus erythematosus
0.709 0.291 0.000
M31 Other necrotising vasculopathies
0.709 0.291 0.000
M30 Polyarteritis nodosa and related conditions
0.709 0.291 0.000
M79.79 Fibromyalgia (Site unspecified)
0.709 0.291 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.709 0.291 0.000
Z36 Antenatal screening
0.709 0.291 0.000
E10-E14 Diabetes mellitus
0.708 0.292 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.708 0.292 0.000
G93 Other disorders of brain
0.708 0.292 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.708 0.292 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.707 0.293 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.706 0.294 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.706 0.294 0.000
C91.1 Chronic lymphocytic leukaemia
0.706 0.294 0.000
M79.66 Pain in limb (Lower leg)
0.705 0.295 0.000
M25.4 Effusion of joint
0.705 0.295 0.000
M76 Enthesopathies of lower limb, excluding foot
0.704 0.296 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.704 0.296 0.000
M71 Other bursopathies
0.704 0.296 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.704 0.296 0.000
F41.2 Mixed anxiety and depressive disorder
0.704 0.296 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.704 0.296 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.704 0.296 0.000
L30 Other dermatitis
0.704 0.296 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.703 0.297 0.000
O72.1 Other immediate postpartum haemorrhage
0.703 0.297 0.000
K28 Gastrojejunal ulcer
0.702 0.298 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.702 0.298 0.000
Z30 Contraceptive management
0.702 0.298 0.000
E73 Lactose intolerance
0.702 0.298 0.000
Z96.8 Presence of other specified functional implants
0.701 0.298 0.000
H53.2 Diplopia
0.701 0.299 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.699 0.300 0.000
Z93 Artificial opening status
0.699 0.301 0.000
I35 Nonrheumatic aortic valve disorders
0.699 0.301 0.000
O45 Premature separation of placenta [abruptio placentae]
0.699 0.301 0.000
O43 Placental disorders
0.699 0.301 0.000
O41 Other disorders of amniotic fluid and membranes
0.699 0.301 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.699 0.301 0.000
O33 Maternal care for known or suspected disproportion
0.699 0.301 0.000
O31 Complications specific to multiple gestation
0.699 0.301 0.000
O40 Polyhydramnios
0.699 0.301 0.000
M22.8 Other disorders of patella
0.697 0.303 0.000
J81 Pulmonary oedema
0.696 0.304 0.000
O42 Premature rupture of membranes
0.696 0.304 0.000
D03 Melanoma in situ
0.695 0.305 0.000
J37 Chronic laryngitis and laryngotracheitis
0.695 0.305 0.000
K66.9 Disorder of peritoneum, unspecified
0.695 0.305 0.000
K66.8 Other specified disorders of peritoneum
0.695 0.305 0.000
K66.1 Haemoperitoneum
0.695 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.694 0.306 0.000
R31 Unspecified haematuria
0.694 0.306 0.000
L40-L45 Papulosquamous disorders
0.694 0.306 0.000
K31 Other diseases of stomach and duodenum
0.694 0.306 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.694 0.306 0.000
M25.9 Joint disorder, unspecified
0.694 0.306 0.000
M25.8 Other specified joint disorders
0.694 0.306 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.694 0.306 0.000
M25.3 Other instability of joint
0.694 0.306 0.000
M25.2 Flail joint
0.694 0.306 0.000
M25.1 Fistula of joint
0.694 0.306 0.000
M25.0 Haemarthrosis
0.694 0.306 0.000
Chapter XXII Codes for special purposes
0.694 0.306 0.000
K29.4 Chronic atrophic gastritis
0.694 0.306 0.000
M79.9 Soft tissue disorder, unspecified
0.693 0.306 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.693 0.306 0.000
M79.3 Panniculitis, unspecified
0.693 0.306 0.000
M79.2 Neuralgia and neuritis, unspecified
0.693 0.306 0.000
M79.1 Myalgia
0.693 0.306 0.000
M35.0 Sicca syndrome [Sjogren]
0.693 0.307 0.000
H54 Blindness and low vision
0.693 0.307 0.000
C67 Malignant neoplasm of bladder
0.691 0.309 0.000
Y52 Agents primarily affecting the cardiovascular system
0.691 0.309 0.000
M65 Synovitis and tenosynovitis
0.691 0.309 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.691 0.309 0.000
O47 False labour
0.690 0.310 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.690 0.310 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.689 0.311 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.689 0.311 0.000
L85 Other epidermal thickening
0.689 0.311 0.000
O36.8 Maternal care for other specified foetal problems
0.689 0.311 0.000
K35-K38 Diseases of appendix
0.688 0.312 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.688 0.312 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.687 0.312 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.687 0.312 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.687 0.313 0.000
G58 Other mononeuropathies
0.687 0.313 0.000
G54 Nerve root and plexus disorders
0.687 0.313 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.687 0.313 0.000
G52 Disorders of other cranial nerves
0.687 0.313 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.687 0.313 0.000
D64.9 Anaemia, unspecified
0.687 0.313 0.000
J84 Other interstitial pulmonary diseases
0.686 0.314 0.000
H25 Senile cataract
0.686 0.314 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.685 0.315 0.000
F99-F99 Unspecified mental disorder
0.685 0.315 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.685 0.315 0.000
F80-F89 Disorders of psychological development
0.685 0.315 0.000
F70-F79 Mental retardation
0.685 0.315 0.000
F60-F69 Disorders of adult personality and behaviour
0.685 0.315 0.000
J32.0 Chronic maxillary sinusitis
0.685 0.315 0.000
M25.59 Pain in joint (Site unspecified)
0.685 0.315 0.000
M25.58 Pain in joint (Other)
0.685 0.315 0.000
M25.53 Pain in joint (Forearm)
0.685 0.315 0.000
M25.52 Pain in joint (Upper arm)
0.685 0.315 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.685 0.315 0.000
W20-W49 Exposure to inanimate mechanical forces
0.684 0.316 0.000
M07 Psoriatic and enteropathic arthropathies
0.684 0.316 0.000
J36 Peritonsillar abscess
0.684 0.316 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.683 0.316 0.000
G20-G26 Extrapyramidal and movement disorders
0.683 0.317 0.000
F40 Phobic anxiety disorders
0.683 0.317 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.683 0.317 0.000
M54.55 Low back pain (Thoracolumbar region)
0.683 0.317 0.000
M54.54 Low back pain-Thoracic
0.683 0.317 0.000
M54.53 Low back pain-Cervicothoracic
0.683 0.317 0.000
M54.52 Low back pain-Cervical
0.683 0.317 0.000
M54.51 Low back pain-Occipit-atl-axl
0.683 0.317 0.000
M54.50 Low back pain (Multiple sites in spine)
0.683 0.317 0.000
M14 Arthropathies in other diseases classified elsewhere
0.682 0.318 0.000
M12 Other specific arthropathies
0.682 0.318 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.682 0.318 0.000
M08 Juvenile arthritis
0.682 0.318 0.000
M49 Spondylopathies in diseases classified elsewhere
0.682 0.318 0.000
E16 Other disorders of pancreatic internal secretion
0.682 0.318 0.000
I00-I02 Acute rheumatic fever
0.682 0.318 0.000
I95 Hypotension
0.682 0.318 0.000
M22.2 Patellofemoral disorders
0.682 0.318 0.000
E04 Other non-toxic goitre
0.682 0.318 0.000
G47.3 Sleep apnoea
0.680 0.320 0.000
T66-T78 Other and unspecified effects of external causes
0.680 0.320 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.680 0.320 0.000
M48 Other spondylopathies
0.680 0.320 0.000
T79-T79 Certain early complications of trauma
0.680 0.320 0.000
K44 Diaphragmatic hernia
0.680 0.320 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.679 0.320 0.000
Z91.7 Personal history of female genital mutilation
0.679 0.320 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.679 0.320 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.679 0.320 0.000
Z91.2 Personal history of poor personal hygiene
0.679 0.320 0.000
K77 Liver disorders in diseases classified elsewhere
0.679 0.321 0.000
K73 Chronic hepatitis, not elsewhere classified
0.679 0.321 0.000
K71 Toxic liver disease
0.679 0.321 0.000
M72 Fibroblastic disorders
0.679 0.321 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.678 0.321 0.000
M41 Scoliosis
0.678 0.322 0.000
Z96.1 Presence of intraocular lens
0.678 0.322 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.678 0.322 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.678 0.322 0.000
S60-S69 Injuries to the wrist and hand
0.677 0.323 0.000
B35-B49 Mycoses
0.676 0.323 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.676 0.324 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.676 0.324 0.000
H10-H13 Disorders of conjunctiva
0.676 0.324 0.000
M50.3 Other cervical disk degeneration
0.676 0.324 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.675 0.325 0.000
K29.0 Acute haemorrhagic gastritis
0.675 0.325 0.000
K22.2 Oesophageal obstruction
0.675 0.325 0.000
C15 Malignant neoplasm of oesophagus
0.674 0.326 0.000
M79.62 Pain in limb (Upper arm)
0.673 0.327 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.672 0.327 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.672 0.328 0.000
E20-E35 Disorders of other endocrine glands
0.672 0.328 0.000
K22.5 Diverticulum of oesophagus, acquired
0.671 0.329 0.000
K22.3 Perforation of oesophagus
0.671 0.329 0.000
K22.0 Achalasia of cardia
0.671 0.329 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.671 0.329 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.671 0.329 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.671 0.329 0.000
C21 Malignant neoplasm of anus and anal canal
0.671 0.329 0.000
C17 Malignant neoplasm of small intestine
0.671 0.329 0.000
C23 Malignant neoplasm of gallbladder
0.671 0.329 0.000
L10-L14 Bullous disorders
0.671 0.329 0.000
A41 Other septicaemia
0.671 0.329 0.000
E40-E46 Malnutrition
0.670 0.330 0.000
K90 Intestinal malabsorption
0.670 0.330 0.000
J60-J70 Lung diseases due to external agents
0.670 0.330 0.000
C44.7 Skin of lower limb, including hip
0.670 0.330 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.669 0.330 0.000
G41 Status epilepticus
0.669 0.330 0.000
K46 Unspecified abdominal hernia
0.669 0.331 0.000
D23.4 Skin of scalp and neck
0.668 0.332 0.000
M11 Other crystal arthropathies
0.668 0.332 0.000
Z88.2 Personal history of allergy to sulphonamides
0.668 0.332 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.667 0.333 0.000
G56.8 Other mononeuropathies of upper limb
0.667 0.333 0.000
G56.4 Causalgia
0.667 0.333 0.000
G56.3 Lesion of radial nerve
0.667 0.333 0.000
G56.1 Other lesions of median nerve
0.667 0.333 0.000
K25 Gastric ulcer
0.667 0.333 0.000
G56.2 Lesion of ulnar nerve
0.667 0.333 0.000
K65.0 Acute peritonitis
0.666 0.334 0.000
G57 Mononeuropathies of lower limb
0.665 0.335 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.665 0.335 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.665 0.335 0.000
J80 Adult respiratory distress syndrome
0.664 0.336 0.000
L91 Hypertrophic disorders of skin
0.664 0.336 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.663 0.337 0.000
K65.9 Peritonitis, unspecified
0.663 0.337 0.000
H30-H36 Disorders of choroid and retina
0.663 0.337 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.663 0.337 0.000
I50 Heart failure
0.663 0.337 0.000
M79.60 Pain in limb (Multiple sites)
0.662 0.337 0.000
D04 Carcinoma in situ of skin
0.662 0.338 0.000
R20.2 Paraesthesia of skin
0.662 0.338 0.000
C44.5 Skin of trunk
0.662 0.338 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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