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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17372597
log Bayes Factor = 15.796
Chromosome 8   position 125,595,153  (GRCh37) Explore rs17372597 on Ensembl!
Variant rs17372597 is part of Cluster X0019

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
0.998 0.002 0.000
Chapter II Neoplasms
0.989 0.011 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
K50 Crohn's disease [regional enteritis]
0.989 0.011 0.000
I51 Complications and ill-defined descriptions of heart disease
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.987 0.013 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.986 0.014 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.980 0.020 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.972 0.028 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.971 0.029 0.000
Chapter X Diseases of the respiratory system
0.971 0.029 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.970 0.030 0.000
D00-D09 In situ neoplasms
0.968 0.032 0.000
C44 Other malignant neoplasms of skin
0.966 0.034 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.966 0.034 0.000
E70-E90 Metabolic disorders
0.963 0.037 0.000
K50.9 Crohn's disease, unspecified
0.958 0.042 0.000
K35-K38 Diseases of appendix
0.957 0.043 0.000
J95-J99 Other diseases of the respiratory system
0.956 0.044 0.000
K52 Other non-infective gastro-enteritis and colitis
0.950 0.050 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.950 0.050 0.000
L40-L45 Papulosquamous disorders
0.948 0.052 0.000
Chapter I Certain infectious and parasitic diseases
0.948 0.052 0.000
C44.7 Skin of lower limb, including hip
0.945 0.055 0.000
K04 Diseases of pulp and periapical tissues
0.945 0.055 0.000
Chapter VIII Diseases of the ear and mastoid process
0.944 0.056 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.944 0.056 0.000
I50 Heart failure
0.942 0.058 0.000
E86 Volume depletion
0.938 0.062 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.936 0.064 0.000
J98 Other respiratory disorders
0.936 0.064 0.000
I51.7 Cardiomegaly
0.934 0.066 0.000
G90-G99 Other disorders of the nervous system
0.933 0.067 0.000
I51.9 Heart disease, unspecified
0.932 0.068 0.000
L40 Psoriasis
0.928 0.072 0.000
I42 Cardiomyopathy
0.926 0.074 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.924 0.076 0.000
I47 Paroxysmal tachycardia
0.921 0.079 0.000
J98.1 Pulmonary collapse
0.915 0.085 0.000
F10.2 Dependence syndrome
0.914 0.086 0.000
K29 Gastritis and duodenitis
0.911 0.089 0.000
L40.9 Psoriasis, unspecified
0.910 0.090 0.000
I50.9 Heart failure, unspecified
0.906 0.094 0.000
D05 Carcinoma in situ of breast
0.905 0.095 0.000
B95-B98 Bacterial, viral and other infectious agents
0.903 0.097 0.000
K29.8 Duodenitis
0.902 0.098 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.900 0.100 0.000
I34 Nonrheumatic mitral valve disorders
0.896 0.104 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.894 0.106 0.000
D60-D64 Aplastic and other anaemias
0.893 0.107 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.891 0.109 0.000
J00-J06 Acute upper respiratory infections
0.889 0.111 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.886 0.114 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.882 0.118 0.000
C44.5 Skin of trunk
0.880 0.120 0.000
H90-H95 Other disorders of ear
0.880 0.120 0.000
E78.5 Hyperlipidaemia, unspecified
0.879 0.121 0.000
K35 Acute appendicitis
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.872 0.128 0.000
E10-E14 Diabetes mellitus
0.868 0.132 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.865 0.135 0.000
A00-A09 Intestinal infectious diseases
0.865 0.135 0.000
L60-L75 Disorders of skin appendages
0.860 0.140 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.859 0.141 0.000
F17.1 Harmful use
0.858 0.142 0.000
F10.1 Harmful use
0.857 0.143 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.855 0.145 0.000
D64 Other anaemias
0.853 0.147 0.000
I47.1 Supraventricular tachycardia
0.853 0.147 0.000
I77 Other disorders of arteries and arterioles
0.851 0.149 0.000
D05.1 Intraductal carcinoma in situ
0.848 0.152 0.000
J09-J18 Influenza and pneumonia
0.848 0.152 0.000
G40-G47 Episodic and paroxysmal disorders
0.847 0.153 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.846 0.154 0.000
K04.8 Radicular cyst
0.844 0.156 0.000
C43 Malignant melanoma of skin
0.843 0.157 0.000
K37 Unspecified appendicitis
0.842 0.158 0.000
K07 Dentofacial anomalies [including malocclusion]
0.838 0.162 0.000
J06.9 Acute upper respiratory infection, unspecified
0.838 0.162 0.000
K50.8 Other Crohn's disease
0.838 0.162 0.000
I74 Arterial embolism and thrombosis
0.835 0.165 0.000
H65-H75 Diseases of middle ear and mastoid
0.834 0.166 0.000
K35.9 Acute appendicitis, unspecified
0.832 0.168 0.000
O60-O75 Complications of labour and delivery
0.832 0.168 0.000
G91 Hydrocephalus
0.826 0.174 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.826 0.174 0.000
I34.0 Mitral (valve) insufficiency
0.826 0.174 0.000
K22 Other diseases of oesophagus
0.825 0.175 0.000
D64.9 Anaemia, unspecified
0.824 0.176 0.000
F10.0 Acute intoxication
0.823 0.177 0.000
I73 Other peripheral vascular diseases
0.821 0.179 0.000
Chapter XXII Codes for special purposes
0.820 0.180 0.000
K51 Ulcerative colitis
0.819 0.181 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.818 0.182 0.000
F17.2 Dependence syndrome
0.817 0.183 0.000
I71 Aortic aneurysm and dissection
0.816 0.184 0.000
I49 Other cardiac arrhythmias
0.816 0.184 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.815 0.185 0.000
K50.1 Crohn's disease of large intestine
0.815 0.185 0.000
D04 Carcinoma in situ of skin
0.812 0.188 0.000
O42 Premature rupture of membranes
0.809 0.191 0.000
I31 Other diseases of pericardium
0.809 0.191 0.000
A08 Viral and other specified intestinal infections
0.808 0.192 0.000
C44.1 Skin of eyelid, including canthus
0.806 0.194 0.000
K90-K93 Other diseases of the digestive system
0.805 0.195 0.000
G93 Other disorders of brain
0.803 0.197 0.000
I36 Nonrheumatic tricuspid valve disorders
0.802 0.198 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.799 0.201 0.000
D03 Melanoma in situ
0.799 0.201 0.000
I44 Atrioventricular and left bundle-branch block
0.799 0.201 0.000
K50.0 Crohn's disease of small intestine
0.799 0.201 0.000
K04.6 Periapical abscess with sinus
0.799 0.201 0.000
I10-I15 Hypertensive diseases
0.797 0.203 0.000
K29.6 Other gastritis
0.797 0.203 0.000
I42.2 Other hypertrophic cardiomyopathy
0.796 0.204 0.000
C34 Malignant neoplasm of bronchus and lung
0.792 0.208 0.000
M80-M85 Disorders of bone density and structure
0.788 0.212 0.000
O20 Haemorrhage in early pregnancy
0.786 0.214 0.000
H91 Other hearing loss
0.784 0.216 0.000
L82 Seborrhoeic keratosis
0.784 0.216 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.783 0.217 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.781 0.219 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.781 0.219 0.000
D09 Carcinoma in situ of other and unspecified sites
0.778 0.221 0.000
L20-L30 Dermatitis and eczema
0.777 0.223 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.773 0.226 0.000
K40-K46 Hernia
0.771 0.229 0.000
K13 Other diseases of lip and oral mucosa
0.770 0.230 0.000
E65-E68 Obesity and other hyperalimentation
0.770 0.230 0.000
Q60-Q64 Congenital malformations of the urinary system
0.770 0.230 0.000
I51.8 Other ill-defined heart diseases
0.769 0.231 0.000
I73.0 Raynaud's syndrome
0.767 0.233 0.000
A08.4 Viral intestinal infection, unspecified
0.767 0.233 0.000
G43 Migraine
0.767 0.233 0.000
F10.3 Withdrawal state
0.766 0.234 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.764 0.236 0.000
E10 Insulin-dependent diabetes mellitus
0.763 0.237 0.000
C44.2 Skin of ear and external auricular canal
0.762 0.238 0.000
C43.5 Malignant melanoma of trunk
0.762 0.238 0.000
S00-S09 Injuries to the head
0.759 0.241 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.757 0.242 0.000
K05 Gingivitis and periodontal diseases
0.757 0.243 0.000
I42.0 Dilated cardiomyopathy
0.756 0.244 0.000
E40-E46 Malnutrition
0.755 0.245 0.000
K65-K67 Diseases of peritoneum
0.754 0.246 0.000
G70-G73 Diseases of myoneural junction and muscle
0.754 0.246 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.754 0.246 0.000
E20-E35 Disorders of other endocrine glands
0.753 0.247 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.753 0.247 0.000
K04.7 Periapical abscess without sinus
0.752 0.248 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.752 0.248 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.751 0.249 0.000
Chapter XXI Factors influencing health status and contact with health services
0.751 0.249 0.000
I12 Hypertensive renal disease
0.751 0.249 0.000
C44.0 Skin of lip
0.749 0.250 0.000
G91.9 Hydrocephalus, unspecified
0.749 0.251 0.000
I27 Other pulmonary heart diseases
0.748 0.252 0.000
D62 Acute posthaemorrhagic anaemia
0.747 0.253 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.744 0.256 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.744 0.256 0.000
G30-G32 Other degenerative diseases of the nervous system
0.743 0.257 0.000
I77.1 Stricture of artery
0.742 0.258 0.000
C34.1 Upper lobe, bronchus or lung
0.742 0.258 0.000
K52.1 Toxic gastro-enteritis and colitis
0.740 0.260 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.737 0.263 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.737 0.263 0.000
I33 Acute and subacute endocarditis
0.737 0.263 0.000
K07.3 Anomalies of tooth position
0.732 0.268 0.000
K26 Duodenal ulcer
0.732 0.268 0.000
H90 Conductive and sensorineural hearing loss
0.731 0.269 0.000
S90-S99 Injuries to the ankle and foot
0.731 0.269 0.000
A80-A89 Viral infections of the central nervous system
0.731 0.269 0.000
K00 Disorders of tooth development and eruption
0.731 0.269 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.731 0.269 0.000
E14 Unspecified diabetes mellitus
0.730 0.270 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.730 0.270 0.000
G20-G26 Extrapyramidal and movement disorders
0.730 0.270 0.000
F60-F69 Disorders of adult personality and behaviour
0.729 0.271 0.000
G47 Sleep disorders
0.729 0.271 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.728 0.272 0.000
J18 Pneumonia, organism unspecified
0.728 0.272 0.000
K22.8 Other specified diseases of oesophagus
0.726 0.274 0.000
K14 Diseases of tongue
0.725 0.275 0.000
J98.8 Other specified respiratory disorders
0.724 0.275 0.000
I05-I09 Chronic rheumatic heart diseases
0.722 0.278 0.000
I42.9 Cardiomyopathy, unspecified
0.720 0.280 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.720 0.280 0.000
L93 Lupus erythematosus
0.720 0.280 0.000
I50.0 Congestive heart failure
0.720 0.280 0.000
K38 Other diseases of appendix
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.717 0.283 0.000
H91.9 Hearing loss, unspecified
0.715 0.285 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.714 0.286 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.714 0.286 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.713 0.287 0.000
H92 Otalgia and effusion of ear
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.291 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.709 0.291 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.291 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.709 0.291 0.000
F99-F99 Unspecified mental disorder
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
I51.6 Cardiovascular disease, unspecified
0.708 0.292 0.000
I51.5 Myocardial degeneration
0.708 0.292 0.000
I51.4 Myocarditis, unspecified
0.708 0.292 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.708 0.292 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.708 0.292 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.708 0.292 0.000
I51.0 Cardiac septal defect, acquired
0.708 0.292 0.000
K25 Gastric ulcer
0.708 0.292 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.707 0.292 0.000
L10-L14 Bullous disorders
0.707 0.293 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.707 0.293 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.707 0.293 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.707 0.293 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.707 0.293 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.707 0.293 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.707 0.293 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.707 0.293 0.000
F11 Mental and behavioural disorders due to use of opioids
0.707 0.293 0.000
I72 Other aneurysm
0.705 0.295 0.000
L71 Rosacea
0.705 0.295 0.000
G93.6 Cerebral oedema
0.705 0.295 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.705 0.295 0.000
S50-S59 Injuries to the elbow and forearm
0.704 0.296 0.000
D06 Carcinoma in situ of cervix uteri
0.703 0.297 0.000
I47.2 Ventricular tachycardia
0.703 0.297 0.000
K10 Other diseases of jaws
0.701 0.299 0.000
K22.1 Ulcer of oesophagus
0.701 0.299 0.000
K11 Diseases of salivary glands
0.699 0.301 0.000
L40.5 Arthropathic psoriasis
0.699 0.301 0.000
F10.9 Unspecified mental and behavioural disorder
0.697 0.303 0.000
F10.8 Other mental and behavioural disorders
0.697 0.303 0.000
F10.7 Residual and late-onset psychotic disorder
0.697 0.303 0.000
F10.6 Amnesic syndrome
0.697 0.303 0.000
F10.5 Psychotic disorder
0.697 0.303 0.000
F10.4 Withdrawal state with delirium
0.697 0.303 0.000
I12.0 Hypertensive renal disease with renal failure
0.697 0.303 0.000
J98.4 Other disorders of lung
0.697 0.303 0.000
D80-D89 Certain disorders involving the immune mechanism
0.697 0.303 0.000
K09 Cysts of oral region, not elsewhere classified
0.696 0.303 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.696 0.303 0.000
K03 Other diseases of hard tissues of teeth
0.696 0.303 0.000
Q61 Cystic kidney disease
0.696 0.304 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.696 0.304 0.000
E83 Disorders of mineral metabolism
0.696 0.304 0.000
O26.9 Pregnancy-related condition, unspecified
0.695 0.304 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.695 0.305 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.695 0.305 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.694 0.306 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.694 0.306 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.694 0.306 0.000
O73 Retained placenta and membranes, without haemorrhage
0.693 0.307 0.000
K29.5 Chronic gastritis, unspecified
0.693 0.307 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.693 0.307 0.000
C44.8 Overlapping lesion of skin
0.693 0.307 0.000
H72 Perforation of tympanic membrane
0.693 0.307 0.000
O85-O92 Complications predominantly related to the puerperium
0.692 0.308 0.000
L84 Corns and callosities
0.692 0.308 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.691 0.309 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.691 0.309 0.000
L40.0 Psoriasis vulgaris
0.691 0.309 0.000
S40-S49 Injuries to the shoulder and upper arm
0.691 0.309 0.000
K92 Other diseases of digestive system
0.690 0.310 0.000
E85 Amyloidosis
0.690 0.310 0.000
E84 Cystic fibrosis
0.690 0.310 0.000
E79 Disorders of purine and pyrimidine metabolism
0.690 0.310 0.000
E77 Disorders of glycoprotein metabolism
0.690 0.310 0.000
E76 Disorders of glycosaminoglycan metabolism
0.690 0.310 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.690 0.310 0.000
E74 Other disorders of carbohydrate metabolism
0.690 0.310 0.000
E73 Lactose intolerance
0.690 0.310 0.000
E72 Other disorders of amino-acid metabolism
0.690 0.310 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.690 0.310 0.000
E70 Disorders of aromatic amino-acid metabolism
0.690 0.310 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.690 0.310 0.000
K27 Peptic ulcer, site unspecified
0.689 0.311 0.000
C32 Malignant neoplasm of larynx
0.689 0.311 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.688 0.312 0.000
O43 Placental disorders
0.688 0.312 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.688 0.312 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.688 0.312 0.000
D05.0 Lobular carcinoma in situ
0.688 0.312 0.000
K36 Other appendicitis
0.686 0.314 0.000
K41 Femoral hernia
0.686 0.314 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.685 0.314 0.000
J96 Respiratory failure, not elsewhere classified
0.685 0.314 0.000
M15-M19 Arthrosis
0.685 0.315 0.000
I31.3 Pericardial effusion (noninflammatory)
0.683 0.316 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.683 0.317 0.000
K21 Gastro-oesophageal reflux disease
0.683 0.317 0.000
B25-B34 Other viral diseases
0.682 0.317 0.000
K04.5 Chronic apical periodontitis
0.682 0.318 0.000
K52.3 Indeterminate colitis
0.681 0.319 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.681 0.319 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.681 0.319 0.000
K28 Gastrojejunal ulcer
0.681 0.319 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.681 0.319 0.000
K22.9 Disease of oesophagus, unspecified
0.680 0.320 0.000
I70 Atherosclerosis
0.680 0.320 0.000
L44 Other papulosquamous disorders
0.680 0.320 0.000
L41 Parapsoriasis
0.680 0.320 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.680 0.320 0.000
L42 Pityriasis rosea
0.680 0.320 0.000
B99-B99 Other infectious diseases
0.680 0.320 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.680 0.320 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.680 0.320 0.000
B65-B83 Helminthiases
0.680 0.320 0.000
B50-B64 Protozoal diseases
0.680 0.320 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.680 0.320 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.680 0.320 0.000
A75-A79 Rickettsioses
0.680 0.320 0.000
A70-A74 Other diseases caused by chlamydiae
0.680 0.320 0.000
A65-A69 Other spirochaetal diseases
0.680 0.320 0.000
A20-A28 Certain zoonotic bacterial diseases
0.680 0.320 0.000
A15-A19 Tuberculosis
0.680 0.320 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.680 0.320 0.000
K80 Cholelithiasis
0.680 0.320 0.000
I38 Endocarditis, valve unspecified
0.679 0.320 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.679 0.321 0.000
M84 Disorders of continuity of bone
0.679 0.321 0.000
I49.3 Ventricular premature depolarisation
0.678 0.322 0.000
J95.8 Other postprocedural respiratory disorders
0.678 0.322 0.000
K04.3 Abnormal hard tissue formation in pulp
0.677 0.322 0.000
K04.2 Pulp degeneration
0.677 0.322 0.000
K04.1 Necrosis of pulp
0.677 0.322 0.000
K04.0 Pulpitis
0.677 0.322 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.677 0.323 0.000
D55-D59 Haemolytic anaemias
0.677 0.323 0.000
L81 Other disorders of pigmentation
0.677 0.323 0.000
L65 Other nonscarring hair loss
0.675 0.325 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.674 0.326 0.000
K12 Stomatitis and related lesions
0.674 0.326 0.000
K92.0 Haematemesis
0.672 0.328 0.000
F17.9 Unspecified mental and behavioural disorder
0.671 0.328 0.000
F17.8 Other mental and behavioural disorders
0.671 0.328 0.000
F17.7 Residual and late-onset psychotic disorder
0.671 0.328 0.000
F17.6 Amnesic syndrome
0.671 0.328 0.000
F17.5 Psychotic disorder
0.671 0.328 0.000
F17.4 Withdrawal state with delirium
0.671 0.328 0.000
F17.3 Withdrawal state
0.671 0.328 0.000
F17.0 Acute intoxication
0.671 0.328 0.000
J98.9 Respiratory disorder, unspecified
0.671 0.329 0.000
J98.6 Disorders of diaphragm
0.671 0.329 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.671 0.329 0.000
J98.3 Compensatory emphysema
0.671 0.329 0.000
J98.2 Interstitial emphysema
0.671 0.329 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.671 0.329 0.000
G56 Mononeuropathies of upper limb
0.670 0.330 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.670 0.330 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.669 0.331 0.000
G96 Other disorders of central nervous system
0.669 0.331 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.669 0.331 0.000
G90 Disorders of autonomic nervous system
0.669 0.331 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.669 0.331 0.000
G92 Toxic encephalopathy
0.669 0.331 0.000
I27.0 Primary pulmonary hypertension
0.669 0.331 0.000
C15-C26 Malignant neoplasms of digestive organs
0.669 0.331 0.000
M81 Osteoporosis without pathological fracture
0.669 0.331 0.000
O21 Excessive vomiting in pregnancy
0.668 0.331 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.668 0.332 0.000
G43.1 Migraine with aura [classical migraine]
0.668 0.332 0.000
K51.5 Mucosal proctocolitis
0.668 0.332 0.000
J11 Influenza, virus not identified
0.668 0.332 0.000
D10-D36 Benign neoplasms
0.668 0.332 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.667 0.333 0.000
I44.0 Atrioventricular block, first degree
0.667 0.333 0.000
H65 Nonsuppurative otitis media
0.666 0.334 0.000
C43.9 Malignant melanoma of skin, unspecified
0.666 0.334 0.000
M05-M14 Inflammatory polyarthropathies
0.666 0.334 0.000
L40.8 Other psoriasis
0.666 0.334 0.000
L40.4 Guttate psoriasis
0.666 0.334 0.000
L40.3 Pustulosis palmaris et plantaris
0.666 0.334 0.000
L40.2 Acrodermatitis continua
0.666 0.334 0.000
L40.1 Generalised pustular psoriasis
0.666 0.334 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.664 0.336 0.000
I42.8 Other cardiomyopathies
0.664 0.336 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.664 0.336 0.000
I42.6 Alcoholic cardiomyopathy
0.664 0.336 0.000
I42.5 Other restrictive cardiomyopathy
0.664 0.336 0.000
I42.4 Endocardial fibroelastosis
0.664 0.336 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.664 0.336 0.000
O61 Failed induction of labour
0.663 0.337 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.662 0.338 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.662 0.338 0.000
T66-T78 Other and unspecified effects of external causes
0.662 0.338 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.662 0.338 0.000
I77.6 Arteritis, unspecified
0.661 0.339 0.000
S80-S89 Injuries to the knee and lower leg
0.661 0.339 0.000
C51-C58 Malignant neoplasms of female genital organs
0.661 0.339 0.000
O62 Abnormalities of forces of labour
0.661 0.339 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.660 0.340 0.000
I47.0 Reentry ventricular arrhythmia
0.660 0.340 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.660 0.340 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.659 0.341 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.659 0.341 0.000
S20-S29 Injuries to the thorax
0.658 0.342 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.658 0.342 0.000
E14.9 Without complications
0.657 0.342 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.657 0.343 0.000
H74 Other disorders of middle ear and mastoid
0.657 0.343 0.000
O48 Prolonged pregnancy
0.656 0.344 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.655 0.345 0.000
L89 Decubitus ulcer
0.654 0.346 0.000
L72.1 Trichilemmal cyst
0.654 0.346 0.000
I49.0 Ventricular fibrillation and flutter
0.654 0.346 0.000
M86-M90 Other osteopathies
0.654 0.346 0.000
K29.9 Gastroduodenitis, unspecified
0.653 0.347 0.000
K29.2 Alcoholic gastritis
0.653 0.347 0.000
F40 Phobic anxiety disorders
0.653 0.347 0.000
D04.7 Skin of lower limb, including hip
0.653 0.347 0.000
J90-J94 Other diseases of pleura
0.652 0.348 0.000
E88 Other metabolic disorders
0.651 0.349 0.000
D04.5 Skin of trunk
0.650 0.349 0.000
K13.0 Diseases of lips
0.650 0.350 0.000
B15-B19 Viral hepatitis
0.650 0.350 0.000
T79-T79 Certain early complications of trauma
0.650 0.350 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.650 0.350 0.000
K82 Other diseases of gallbladder
0.649 0.351 0.000
O20.0 Threatened abortion
0.649 0.351 0.000
D05.7 Other carcinoma in situ of breast
0.649 0.351 0.000
I74.5 Embolism and thrombosis of iliac artery
0.646 0.354 0.000
K51.4 Pseudopolyposis of colon
0.646 0.354 0.000
O00-O08 Pregnancy with abortive outcome
0.646 0.354 0.000
D50-D53 Nutritional anaemias
0.646 0.354 0.000
O66 Other obstructed labour
0.646 0.354 0.000
J95.0 Tracheostomy malfunction
0.645 0.355 0.000
I44.1 Atrioventricular block, second degree
0.645 0.355 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.645 0.355 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.645 0.355 0.000
L94 Other localised connective tissue disorders
0.645 0.355 0.000
L87 Transepidermal elimination disorders
0.645 0.355 0.000
L88 Pyoderma gangrenosum
0.645 0.355 0.000
L86 Keratoderma in diseases classified elsewhere
0.645 0.355 0.000
L83 Acanthosis nigricans
0.645 0.355 0.000
L80 Vitiligo
0.645 0.355 0.000
Q50-Q56 Congenital malformations of genital organs
0.645 0.355 0.000
M65-M68 Disorders of synovium and tendon
0.644 0.355 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.644 0.356 0.000
E50-E64 Other nutritional deficiencies
0.644 0.356 0.000
I46 Cardiac arrest
0.643 0.357 0.000
L50-L54 Urticaria and erythema
0.643 0.357 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.643 0.357 0.000
E10.4 With neurological complications
0.643 0.357 0.000
D09.0 Bladder
0.643 0.357 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.643 0.357 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.642 0.358 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.642 0.358 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.642 0.358 0.000
I78 Diseases of capillaries
0.641 0.358 0.000
O29 Complications of anaesthesia during pregnancy
0.641 0.359 0.000
O28 Abnormal findings on antenatal screening of mother
0.641 0.359 0.000
O24 Diabetes mellitus in pregnancy
0.641 0.359 0.000
O23 Infections of genito-urinary tract in pregnancy
0.641 0.359 0.000
O22 Venous complications in pregnancy
0.641 0.359 0.000
O25 Malnutrition in pregnancy
0.641 0.359 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.641 0.359 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.641 0.359 0.000
K44 Diaphragmatic hernia
0.640 0.359 0.000
I49.1 Atrial premature depolarisation
0.640 0.360 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.640 0.360 0.000
E78.8 Other disorders of lipoprotein metabolism
0.639 0.361 0.000
E78.6 Lipoprotein deficiency
0.639 0.361 0.000
E78.4 Other hyperlipidaemia
0.639 0.361 0.000
E78.3 Hyperchylomicronaemia
0.639 0.361 0.000
E78.2 Mixed hyperlipidaemia
0.639 0.361 0.000
E78.1 Pure hyperglyceridaemia
0.639 0.361 0.000
G43.9 Migraine, unspecified
0.639 0.361 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.638 0.362 0.000
S00 Superficial injury of head
0.638 0.362 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.637 0.362 0.000
J04 Acute laryngitis and tracheitis
0.637 0.362 0.000
J01 Acute sinusitis
0.637 0.362 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.637 0.363 0.000
M16 Coxarthrosis [arthrosis of hip]
0.637 0.363 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.635 0.365 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.635 0.365 0.000
C31 Malignant neoplasm of accessory sinuses
0.635 0.365 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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