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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs191939331
log Bayes Factor = 1.86657
Chromosome 8   position 84,717,650  (GRCh37) Explore rs191939331 on Ensembl!
Variant rs191939331 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.985 0.015 0.000
I25 Chronic ischaemic heart disease
0.984 0.016 0.000
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.965 0.035 0.000
# Top node
0.964 0.036 0.000
I25.2 Old myocardial infarction
0.951 0.049 0.000
I21 Acute myocardial infarction
0.925 0.075 0.000
I30-I52 Other forms of heart disease
0.925 0.075 0.000
Chapter VII Diseases of the eye and adnexa
0.917 0.083 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.906 0.094 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.894 0.106 0.000
D60-D64 Aplastic and other anaemias
0.888 0.112 0.000
I25.1 Atherosclerotic heart disease
0.882 0.118 0.000
D64 Other anaemias
0.867 0.133 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.856 0.144 0.000
D64.9 Anaemia, unspecified
0.852 0.148 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.842 0.158 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.819 0.181 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.816 0.184 0.000
H25-H28 Disorders of lens
0.813 0.187 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.812 0.188 0.000
I21.9 Acute myocardial infarction, unspecified
0.810 0.190 0.000
I50 Heart failure
0.810 0.190 0.000
M20-M25 Other joint disorders
0.800 0.200 0.000
O60-O75 Complications of labour and delivery
0.786 0.214 0.000
Chapter VI Diseases of the nervous system
0.784 0.216 0.000
M20 Acquired deformities of fingers and toes
0.777 0.223 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.769 0.230 0.000
I47 Paroxysmal tachycardia
0.768 0.231 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.762 0.238 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.760 0.240 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.756 0.244 0.000
M20.1 Hallux valgus (acquired)
0.753 0.247 0.000
H43-H45 Disorders of vitreous body and globe
0.752 0.248 0.000
S00-S09 Injuries to the head
0.750 0.250 0.000
H26 Other cataract
0.748 0.252 0.000
I84 Haemorrhoids
0.745 0.255 0.000
H53-H54 Visual disturbances and blindness
0.744 0.256 0.000
I60-I69 Cerebrovascular diseases
0.737 0.263 0.000
I24 Other acute ischaemic heart diseases
0.737 0.263 0.000
I35 Nonrheumatic aortic valve disorders
0.735 0.265 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.734 0.266 0.000
I20 Angina pectoris
0.733 0.267 0.000
D62 Acute posthaemorrhagic anaemia
0.728 0.272 0.000
I50.1 Left ventricular failure
0.726 0.274 0.000
S80-S89 Injuries to the knee and lower leg
0.725 0.275 0.000
Chapter VIII Diseases of the ear and mastoid process
0.718 0.282 0.000
Chapter XX External causes of morbidity and mortality
0.713 0.287 0.000
I51 Complications and ill-defined descriptions of heart disease
0.712 0.288 0.000
I45 Other conduction disorders
0.708 0.292 0.000
I23 Certain current complications following acute myocardial infarction
0.706 0.294 0.000
I22 Subsequent myocardial infarction
0.706 0.294 0.000
I25.6 Silent myocardial ischaemia
0.706 0.294 0.000
I25.5 Ischaemic cardiomyopathy
0.706 0.294 0.000
I25.4 Coronary artery aneurysm
0.706 0.294 0.000
I25.3 Aneurysm of heart
0.706 0.294 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.706 0.294 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.705 0.295 0.000
I05-I09 Chronic rheumatic heart diseases
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.705 0.295 0.000
Chapter XIV Diseases of the genitourinary system
0.703 0.297 0.000
I49 Other cardiac arrhythmias
0.697 0.303 0.000
M23 Internal derangement of knee
0.697 0.303 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.697 0.303 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.696 0.304 0.000
I46 Cardiac arrest
0.692 0.308 0.000
Chapter XXII Codes for special purposes
0.691 0.309 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.691 0.309 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.691 0.309 0.000
I70 Atherosclerosis
0.685 0.315 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.682 0.318 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.680 0.319 0.000
I84.1 Internal haemorrhoids with other complications
0.676 0.324 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.675 0.325 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.670 0.330 0.000
I21.4 Acute subendocardial myocardial infarction
0.670 0.330 0.000
H40-H42 Glaucoma
0.667 0.333 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.663 0.337 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.663 0.337 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.663 0.337 0.000
I52 Other heart disorders in diseases classified elsewhere
0.663 0.337 0.000
I48 Atrial fibrillation and flutter
0.663 0.337 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.663 0.337 0.000
I42 Cardiomyopathy
0.663 0.337 0.000
I41 Myocarditis in diseases classified elsewhere
0.663 0.337 0.000
I40 Acute myocarditis
0.663 0.337 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.663 0.337 0.000
I37 Pulmonary valve disorders
0.663 0.337 0.000
I36 Nonrheumatic tricuspid valve disorders
0.663 0.337 0.000
I33 Acute and subacute endocarditis
0.663 0.337 0.000
I32 Pericarditis in diseases classified elsewhere
0.663 0.337 0.000
I31 Other diseases of pericardium
0.663 0.337 0.000
I30 Acute pericarditis
0.663 0.337 0.000
I38 Endocarditis, valve unspecified
0.663 0.337 0.000
H26.9 Cataract, unspecified
0.661 0.339 0.000
H55-H59 Other disorders of eye and adnexa
0.657 0.343 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.657 0.343 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.657 0.343 0.000
H10-H13 Disorders of conjunctiva
0.657 0.343 0.000
I47.1 Supraventricular tachycardia
0.656 0.344 0.000
O80-O84 Delivery
0.652 0.348 0.000
I73 Other peripheral vascular diseases
0.651 0.349 0.000
M20.4 Other hammer toe(s) (acquired)
0.650 0.350 0.000
D80-D89 Certain disorders involving the immune mechanism
0.649 0.350 0.000
D55-D59 Haemolytic anaemias
0.649 0.350 0.000
I71 Aortic aneurysm and dissection
0.649 0.351 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.648 0.352 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.644 0.355 0.000
I44 Atrioventricular and left bundle-branch block
0.644 0.356 0.000
S50-S59 Injuries to the elbow and forearm
0.644 0.356 0.000
O00-O08 Pregnancy with abortive outcome
0.643 0.357 0.000
H02 Other disorders of eyelid
0.642 0.358 0.000
O85-O92 Complications predominantly related to the puerperium
0.641 0.359 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.636 0.364 0.000
D61 Other aplastic anaemias
0.636 0.364 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.636 0.364 0.000
E10-E14 Diabetes mellitus
0.635 0.364 0.000
H26.4 After-cataract
0.635 0.365 0.000
H43 Disorders of vitreous body
0.633 0.367 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.631 0.369 0.000
L60-L75 Disorders of skin appendages
0.628 0.372 0.000
S40-S49 Injuries to the shoulder and upper arm
0.628 0.372 0.000
S00 Superficial injury of head
0.625 0.374 0.000
S70-S79 Injuries to the hip and thigh
0.625 0.375 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.625 0.375 0.000
I10-I15 Hypertensive diseases
0.624 0.376 0.000
S01 Open wound of head
0.623 0.377 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.622 0.378 0.000
D64.8 Other specified anaemias
0.622 0.378 0.000
D64.4 Congenital dyserythropoietic anaemia
0.622 0.378 0.000
D64.3 Other sideroblastic anaemias
0.622 0.378 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.622 0.378 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.622 0.378 0.000
D64.0 Hereditary sideroblastic anaemia
0.622 0.378 0.000
H53 Visual disturbances
0.621 0.379 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.618 0.382 0.000
N30-N39 Other diseases of urinary system
0.618 0.382 0.000
H01 Other inflammation of eyelid
0.616 0.384 0.000
G20-G26 Extrapyramidal and movement disorders
0.615 0.385 0.000
S60-S69 Injuries to the wrist and hand
0.614 0.386 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.613 0.386 0.000
T79-T79 Certain early complications of trauma
0.613 0.386 0.000
T66-T78 Other and unspecified effects of external causes
0.613 0.386 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.613 0.386 0.000
T33-T35 Frostbite
0.613 0.386 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.613 0.386 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.613 0.386 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.613 0.386 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.613 0.386 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.613 0.386 0.000
T00-T07 Injuries involving multiple body regions
0.613 0.386 0.000
S90-S99 Injuries to the ankle and foot
0.613 0.386 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.613 0.386 0.000
S20-S29 Injuries to the thorax
0.613 0.386 0.000
S10-S19 Injuries to the neck
0.613 0.386 0.000
I84.5 External haemorrhoids without complication
0.613 0.387 0.000
M05-M14 Inflammatory polyarthropathies
0.611 0.389 0.000
H30-H36 Disorders of choroid and retina
0.609 0.390 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.603 0.396 0.000
I78 Diseases of capillaries
0.603 0.396 0.000
I77 Other disorders of arteries and arterioles
0.603 0.396 0.000
I74 Arterial embolism and thrombosis
0.603 0.396 0.000
I72 Other aneurysm
0.603 0.396 0.000
I20.0 Unstable angina
0.603 0.397 0.000
I50.9 Heart failure, unspecified
0.601 0.399 0.000
I35.0 Aortic (valve) stenosis
0.599 0.401 0.000
M65-M68 Disorders of synovium and tendon
0.596 0.404 0.000
Chapter V Mental and behavioural disorders
0.594 0.406 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.592 0.408 0.000
I84.2 Internal haemorrhoids without complication
0.591 0.409 0.000
G90-G99 Other disorders of the nervous system
0.591 0.409 0.000
I80 Phlebitis and thrombophlebitis
0.590 0.410 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.587 0.413 0.000
I88 Nonspecific lymphadenitis
0.587 0.413 0.000
I87 Other disorders of veins
0.587 0.413 0.000
I86 Varicose veins of other sites
0.587 0.413 0.000
I85 Oesophageal varices
0.587 0.413 0.000
I82 Other venous embolism and thrombosis
0.587 0.413 0.000
I81 Portal vein thrombosis
0.587 0.413 0.000
E65-E68 Obesity and other hyperalimentation
0.587 0.413 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.586 0.414 0.000
Chapter I Certain infectious and parasitic diseases
0.585 0.415 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.585 0.415 0.000
M91-M94 Chondropathies
0.585 0.415 0.000
M86-M90 Other osteopathies
0.585 0.415 0.000
M60-M63 Disorders of muscles
0.585 0.415 0.000
M40-M43 Deforming dorsopathies
0.585 0.415 0.000
M00-M03 Infectious arthropathies
0.585 0.415 0.000
L40-L45 Papulosquamous disorders
0.584 0.416 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.583 0.417 0.000
H27 Other disorders of lens
0.583 0.417 0.000
H65-H75 Diseases of middle ear and mastoid
0.583 0.417 0.000
L50-L54 Urticaria and erythema
0.582 0.418 0.000
L10-L14 Bullous disorders
0.582 0.418 0.000
O16 Unspecified maternal hypertension
0.581 0.419 0.000
M23.3 Other meniscus derangements
0.581 0.419 0.000
O63 Long labour
0.580 0.420 0.000
M20.5 Other deformities of toe(s) (acquired)
0.578 0.422 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.578 0.422 0.000
I69 Sequelae of cerebrovascular disease
0.577 0.423 0.000
N39 Other disorders of urinary system
0.576 0.424 0.000
I51.8 Other ill-defined heart diseases
0.575 0.425 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.573 0.426 0.000
M35 Other systemic involvement of connective tissue
0.573 0.426 0.000
M34 Systemic sclerosis
0.573 0.426 0.000
M33 Dermatopolymyositis
0.573 0.426 0.000
M32 Systemic lupus erythematosus
0.573 0.426 0.000
M31 Other necrotising vasculopathies
0.573 0.426 0.000
M30 Polyarteritis nodosa and related conditions
0.573 0.426 0.000
M24 Other specific joint derangements
0.573 0.426 0.000
M22 Disorders of patella
0.573 0.426 0.000
M21 Other acquired deformities of limbs
0.573 0.426 0.000
L81 Other disorders of pigmentation
0.573 0.427 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.573 0.427 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.572 0.428 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.570 0.430 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.569 0.431 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.569 0.431 0.000
I84.6 Residual haemorrhoidal skin tags
0.568 0.432 0.000
S80 Superficial injury of lower leg
0.567 0.433 0.000
S82 Fracture of lower leg, including ankle
0.565 0.434 0.000
L20-L30 Dermatitis and eczema
0.565 0.435 0.000
M80-M85 Disorders of bone density and structure
0.563 0.437 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.563 0.437 0.000
O74 Complications of anaesthesia during labour and delivery
0.563 0.437 0.000
O73 Retained placenta and membranes, without haemorrhage
0.563 0.437 0.000
O71 Other obstetric trauma
0.563 0.437 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.563 0.437 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.563 0.437 0.000
O66 Other obstructed labour
0.563 0.437 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.563 0.437 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.563 0.437 0.000
O62 Abnormalities of forces of labour
0.563 0.437 0.000
O61 Failed induction of labour
0.563 0.437 0.000
O60 Preterm delivery
0.563 0.437 0.000
I50.0 Congestive heart failure
0.562 0.438 0.000
G70-G73 Diseases of myoneural junction and muscle
0.562 0.438 0.000
G30-G32 Other degenerative diseases of the nervous system
0.562 0.438 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.562 0.438 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.562 0.438 0.000
O72 Postpartum haemorrhage
0.561 0.439 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.560 0.439 0.000
I24.8 Other forms of acute ischaemic heart disease
0.558 0.441 0.000
L90 Atrophic disorders of skin
0.558 0.442 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.557 0.443 0.000
M20.3 Other deformity of hallux (acquired)
0.557 0.443 0.000
M20.0 Deformity of finger(s)
0.557 0.443 0.000
M45-M49 Spondylopathies
0.557 0.443 0.000
V10-V19 Pedal cyclist injured in transport accident
0.557 0.443 0.000
O70 Perineal laceration during delivery
0.554 0.446 0.000
I45.1 Other and unspecified right bundle-branch block
0.552 0.447 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.551 0.449 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.551 0.449 0.000
I47.2 Ventricular tachycardia
0.551 0.449 0.000
I47.0 Reentry ventricular arrhythmia
0.551 0.449 0.000
G81 Hemiplegia
0.551 0.449 0.000
I49.3 Ventricular premature depolarisation
0.551 0.449 0.000
H25 Senile cataract
0.551 0.449 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.550 0.450 0.000
I51.9 Heart disease, unspecified
0.549 0.451 0.000
M25 Other joint disorders, not elsewhere classified
0.549 0.451 0.000
H43.1 Vitreous haemorrhage
0.549 0.451 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.547 0.453 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.546 0.453 0.000
H05 Disorders of orbit
0.546 0.453 0.000
H04 Disorders of lachrymal system
0.546 0.453 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.546 0.453 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.546 0.454 0.000
E50-E64 Other nutritional deficiencies
0.545 0.455 0.000
E40-E46 Malnutrition
0.545 0.455 0.000
E20-E35 Disorders of other endocrine glands
0.545 0.455 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.542 0.458 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.541 0.458 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.541 0.459 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.539 0.461 0.000
H44 Disorders of globe
0.539 0.461 0.000
S08 Traumatic amputation of part of head
0.538 0.462 0.000
S07 Crushing injury of head
0.538 0.462 0.000
S06 Intracranial injury
0.538 0.462 0.000
S05 Injury of eye and orbit
0.538 0.462 0.000
S04 Injury of cranial nerves
0.538 0.462 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.538 0.462 0.000
S02 Fracture of skull and facial bones
0.538 0.462 0.000
H26.8 Other specified cataract
0.536 0.463 0.000
H26.3 Drug-induced cataract
0.536 0.463 0.000
H26.2 Complicated cataract
0.536 0.463 0.000
H26.1 Traumatic cataract
0.536 0.463 0.000
H26.0 Infantile, juvenile and presenile cataract
0.536 0.463 0.000
S00.8 Superficial injury of other parts of head
0.536 0.464 0.000
N39.3 Stress incontinence
0.534 0.466 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.534 0.466 0.000
I84.4 External haemorrhoids with other complications
0.534 0.466 0.000
I84.3 External thrombosed haemorrhoids
0.534 0.466 0.000
I84.0 Internal thrombosed haemorrhoids
0.534 0.466 0.000
H54 Blindness and low vision
0.534 0.466 0.000
S09 Other and unspecified injuries of head
0.533 0.466 0.000
I34 Nonrheumatic mitral valve disorders
0.533 0.467 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.529 0.471 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.529 0.471 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.529 0.471 0.000
I62 Other nontraumatic intracranial haemorrhage
0.529 0.471 0.000
I61 Intracerebral haemorrhage
0.529 0.471 0.000
I60 Subarachnoid haemorrhage
0.529 0.471 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.528 0.472 0.000
I24.1 Dressler's syndrome
0.528 0.472 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.528 0.472 0.000
I67 Other cerebrovascular diseases
0.528 0.472 0.000
E00-E07 Disorders of thyroid gland
0.528 0.472 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.527 0.473 0.000
I35.9 Aortic valve disorder, unspecified
0.527 0.473 0.000
I35.8 Other aortic valve disorders
0.527 0.473 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.527 0.473 0.000
I35.1 Aortic (valve) insufficiency
0.527 0.473 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.527 0.473 0.000
O15 Eclampsia
0.526 0.474 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.526 0.474 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.526 0.474 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.526 0.474 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.526 0.474 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.526 0.474 0.000
I20.8 Other forms of angina pectoris
0.526 0.474 0.000
I20.1 Angina pectoris with documented spasm
0.526 0.474 0.000
I46.0 Cardiac arrest with successful resuscitation
0.525 0.475 0.000
H02.0 Entropion and trichiasis of eyelid
0.524 0.476 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.522 0.478 0.000
S89 Other and unspecified injuries of lower leg
0.520 0.480 0.000
S88 Traumatic amputation of lower leg
0.520 0.480 0.000
S87 Crushing injury of lower leg
0.520 0.480 0.000
S86 Injury of muscle and tendon at lower leg level
0.520 0.480 0.000
S85 Injury of blood vessels at lower leg level
0.520 0.480 0.000
S84 Injury of nerves at lower leg level
0.520 0.480 0.000
S81 Open wound of lower leg
0.520 0.480 0.000
I73.0 Raynaud's syndrome
0.519 0.480 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.518 0.482 0.000
H80-H83 Diseases of inner ear
0.515 0.485 0.000
H60-H62 Diseases of external ear
0.515 0.485 0.000
N60-N64 Disorders of breast
0.513 0.487 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.513 0.487 0.000
D50-D53 Nutritional anaemias
0.512 0.487 0.000
I84.9 Unspecified haemorrhoids without complication
0.511 0.489 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.511 0.489 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.511 0.489 0.000
Y35-Y36 Legal intervention and operations of war
0.511 0.489 0.000
Y10-Y34 Event of undetermined intent
0.511 0.489 0.000
Y00-Y09 Assault
0.511 0.489 0.000
X85-X99 Assault
0.511 0.489 0.000
X60-X84 Intentional self-harm
0.511 0.489 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.511 0.489 0.000
X50-X57 Overexertion, travel and privation
0.511 0.489 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.511 0.489 0.000
X30-X39 Exposure to forces of nature
0.511 0.489 0.000
X20-X29 Contact with venomous animals and plants
0.511 0.489 0.000
X10-X19 Contact with heat and hot substances
0.511 0.489 0.000
X00-X09 Exposure to smoke, fire and flames
0.511 0.489 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.511 0.489 0.000
W75-W84 Other accidental threats to breathing
0.511 0.489 0.000
W65-W74 Accidental drowning and submersion
0.511 0.489 0.000
W50-W64 Exposure to animate mechanical forces
0.511 0.489 0.000
W20-W49 Exposure to inanimate mechanical forces
0.511 0.489 0.000
V98-V99 Other and unspecified transport accidents
0.511 0.489 0.000
V95-V97 Air and space transport accidents
0.511 0.489 0.000
V90-V94 Water transport accidents
0.511 0.489 0.000
V80-V89 Other land transport accidents
0.511 0.489 0.000
V70-V79 Bus occupant injured in transport accident
0.511 0.489 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.511 0.489 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.511 0.489 0.000
V40-V49 Car occupant injured in transport accident
0.511 0.489 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.511 0.489 0.000
V20-V29 Motorcycle rider injured in transport accident
0.511 0.489 0.000
V01-V09 Pedestrian injured in transport accident
0.511 0.489 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.511 0.489 0.000
E14 Unspecified diabetes mellitus
0.511 0.489 0.000
H01.0 Blepharitis
0.511 0.489 0.000
N30 Cystitis
0.511 0.489 0.000
I51.6 Cardiovascular disease, unspecified
0.510 0.489 0.000
I51.5 Myocardial degeneration
0.510 0.489 0.000
I51.4 Myocarditis, unspecified
0.510 0.489 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.510 0.489 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.510 0.489 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.510 0.489 0.000
I51.0 Cardiac septal defect, acquired
0.510 0.489 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.510 0.490 0.000
I45.9 Conduction disorder, unspecified
0.508 0.492 0.000
I45.8 Other specified conduction disorders
0.508 0.492 0.000
I45.6 Preexcitation syndrome
0.508 0.492 0.000
I45.5 Other specified heart block
0.508 0.492 0.000
I45.4 Nonspecific intraventricular block
0.508 0.492 0.000
I45.3 Trifascicular block
0.508 0.492 0.000
I45.2 Bifascicular block
0.508 0.492 0.000
I45.0 Right fascicular block
0.508 0.492 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.507 0.493 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.506 0.493 0.000
I22.8 Subsequent myocardial infarction of other sites
0.506 0.493 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.506 0.493 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.506 0.493 0.000
I23.8 Other current complications following acute myocardial infarction
0.506 0.493 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.506 0.493 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.506 0.493 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.506 0.493 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.506 0.493 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.506 0.493 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.506 0.493 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.506 0.493 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.506 0.494 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.506 0.494 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.506 0.494 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.506 0.494 0.000
I02 Rheumatic chorea
0.505 0.494 0.000
I01 Rheumatic fever with heart involvement
0.505 0.494 0.000
I00 Rheumatic fever without mention of heart involvement
0.505 0.494 0.000
I09 Other rheumatic heart diseases
0.505 0.494 0.000
I08 Multiple valve diseases
0.505 0.494 0.000
I07 Rheumatic tricuspid valve diseases
0.505 0.494 0.000
I06 Rheumatic aortic valve diseases
0.505 0.494 0.000
I05 Rheumatic mitral valve diseases
0.505 0.494 0.000
H53.1 Subjective visual disturbances
0.506 0.494 0.000
N10-N16 Renal tubulo-interstitial diseases
0.505 0.495 0.000
O47 False labour
0.505 0.495 0.000
S01.1 Open wound of eyelid and periocular area
0.504 0.496 0.000
N99-N99 Other disorders of the genitourinary system
0.504 0.496 0.000
N00-N08 Glomerular diseases
0.504 0.496 0.000
H02.3 Blepharochalasis
0.504 0.496 0.000
I49.8 Other specified cardiac arrhythmias
0.500 0.500 0.000
I49.5 Sick sinus syndrome
0.500 0.500 0.000
I49.4 Other and unspecified premature depolarisation
0.500 0.500 0.000
I49.2 Junctional premature depolarisation
0.500 0.500 0.000
I49.1 Atrial premature depolarisation
0.500 0.500 0.000
I49.0 Ventricular fibrillation and flutter
0.500 0.500 0.000
M23.9 Internal derangement of knee, unspecified
0.500 0.500 0.000
M23.8 Other internal derangements of knee
0.500 0.500 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.500 0.500 0.000
M23.5 Chronic instability of knee
0.500 0.500 0.000
M23.4 Loose body in knee
0.500 0.500 0.000
M23.1 Discoid meniscus (congenital)
0.500 0.500 0.000
M23.0 Cystic meniscus
0.500 0.500 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.500 0.500 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.500 0.500 0.000
L94 Other localised connective tissue disorders
0.500 0.500 0.000
L93 Lupus erythematosus
0.500 0.500 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.500 0.500 0.000
L89 Decubitus ulcer
0.500 0.500 0.000
L87 Transepidermal elimination disorders
0.500 0.500 0.000
L85 Other epidermal thickening
0.500 0.500 0.000
L88 Pyoderma gangrenosum
0.500 0.500 0.000
L86 Keratoderma in diseases classified elsewhere
0.500 0.500 0.000
L84 Corns and callosities
0.500 0.500 0.000
L83 Acanthosis nigricans
0.500 0.500 0.000
L80 Vitiligo
0.500 0.500 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.499 0.501 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.499 0.501 0.000
I99 Other and unspecified disorders of circulatory system
0.499 0.501 0.000
E11 Non-insulin-dependent diabetes mellitus
0.498 0.502 0.000
N25-N29 Other disorders of kidney and ureter
0.497 0.503 0.000
I46.9 Cardiac arrest, unspecified
0.496 0.504 0.000
I46.1 Sudden cardiac death, so described
0.496 0.504 0.000
O36 Maternal care for other known or suspected foetal problems
0.496 0.504 0.000
P90-P96 Other disorders originating in the perinatal period
0.495 0.505 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.495 0.505 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.495 0.505 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.495 0.505 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.495 0.505 0.000
P35-P39 Infections specific to the perinatal period
0.495 0.505 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.495 0.505 0.000
P10-P15 Birth trauma
0.495 0.505 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.495 0.505 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.495 0.505 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.495 0.505 0.000
Q80-Q89 Other congenital malformations
0.495 0.505 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.495 0.505 0.000
Q60-Q64 Congenital malformations of the urinary system
0.495 0.505 0.000
Q50-Q56 Congenital malformations of genital organs
0.495 0.505 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.495 0.505 0.000
Q35-Q37 Cleft lip and cleft palate
0.495 0.505 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.495 0.505 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.495 0.505 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.495 0.505 0.000
Q00-Q07 Congenital malformations of the nervous system
0.495 0.505 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.495 0.505 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.495 0.505 0.000
G20 Parkinson's disease
0.493 0.506 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.493 0.507 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.493 0.507 0.000
H02.4 Ptosis of eyelid
0.492 0.508 0.000
S52 Fracture of forearm
0.492 0.508 0.000
I70.9 Generalised and unspecified atherosclerosis
0.491 0.509 0.000
I70.8 Atherosclerosis of other arteries
0.491 0.509 0.000
I70.1 Atherosclerosis of renal artery
0.491 0.509 0.000
I70.0 Atherosclerosis of aorta
0.491 0.509 0.000
I95 Hypotension
0.490 0.510 0.000
L91 Hypertrophic disorders of skin
0.489 0.511 0.000
N39.9 Disorder of urinary system, unspecified
0.489 0.511 0.000
O45 Premature separation of placenta [abruptio placentae]
0.489 0.511 0.000
O44 Placenta praevia
0.489 0.511 0.000
O43 Placental disorders
0.489 0.511 0.000
O42 Premature rupture of membranes
0.489 0.511 0.000
O41 Other disorders of amniotic fluid and membranes
0.489 0.511 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.489 0.511 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.489 0.511 0.000
O33 Maternal care for known or suspected disproportion
0.489 0.511 0.000
O31 Complications specific to multiple gestation
0.489 0.511 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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