TreeWAS – Variant ID: rs4397449

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
# Top node	0.824	0.176
Chapter XXI Factors influencing health status and contact with health services	0.833	0.167
Chapter IX Diseases of the circulatory system	0.839	0.161
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.848	0.152
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.849	0.151
Chapter X Diseases of the respiratory system	0.853	0.147
Chapter II Neoplasms	0.859	0.141
Chapter I Certain infectious and parasitic diseases	0.859	0.140
Z40-Z54 Persons encountering health services for specific procedures and health care	0.860	0.140
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.861	0.139
I60-I69 Cerebrovascular diseases	0.861	0.139
Chapter V Mental and behavioural disorders	0.863	0.137
Chapter VI Diseases of the nervous system	0.863	0.137
Chapter XI Diseases of the digestive system	0.863	0.137
Chapter XXII Codes for special purposes	0.866	0.134
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.867	0.133
Chapter XIV Diseases of the genitourinary system	0.867	0.133
I30-I52 Other forms of heart disease	0.868	0.132
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.868	0.132
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.868	0.132
Chapter XV Pregnancy, childbirth and the puerperium	0.869	0.131
Z70-Z76 Persons encountering health services in other circumstances	0.870	0.130
J30-J39 Other diseases of upper respiratory tract	0.872	0.128
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.873	0.127
Chapter XVI Certain conditions originating in the perinatal period	0.874	0.126
Chapter IV Endocrine, nutritional and metabolic diseases	0.875	0.125
Chapter VIII Diseases of the ear and mastoid process	0.875	0.125
Chapter XII Diseases of the skin and subcutaneous tissue	0.876	0.124
Chapter XX External causes of morbidity and mortality	0.877	0.123
Z00-Z13 Persons encountering health services for examination and investigation	0.878	0.122
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.878	0.122
I20-I25 Ischaemic heart diseases	0.878	0.122
I10-I15 Hypertensive diseases	0.879	0.121
M70-M79 Other soft tissue disorders	0.879	0.121
M05-M14 Inflammatory polyarthropathies	0.880	0.120
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.881	0.119
Z86 Personal history of certain other diseases	0.881	0.119
I95-I99 Other and unspecified disorders of the circulatory system	0.882	0.118
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.882	0.118
I70-I79 Diseases of arteries, arterioles and capillaries	0.882	0.117
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.884	0.116
I00-I02 Acute rheumatic fever	0.885	0.115
M20-M25 Other joint disorders	0.885	0.115
I05-I09 Chronic rheumatic heart diseases	0.885	0.114
Z90 Acquired absence of organs, not elsewhere classified	0.886	0.114
Chapter VII Diseases of the eye and adnexa	0.886	0.114
M45-M49 Spondylopathies	0.886	0.113
Z50 Care involving use of rehabilitation procedures	0.888	0.112
Z91 Personal history of risk-factors, not elsewhere classified	0.888	0.112
Z85 Personal history of malignant neoplasm	0.888	0.112
Z92 Personal history of medical treatment	0.889	0.111
M80-M85 Disorders of bone density and structure	0.889	0.111
Z95 Presence of cardiac and vascular implants and grafts	0.889	0.111
C50-C50 Malignant neoplasm of breast	0.889	0.111
M50-M54 Other dorsopathies	0.889	0.111
M91-M94 Chondropathies	0.889	0.111
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.889	0.111
M86-M90 Other osteopathies	0.889	0.110
Z93 Artificial opening status	0.890	0.110
M65-M68 Disorders of synovium and tendon	0.890	0.110
B95-B98 Bacterial, viral and other infectious agents	0.890	0.110
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.890	0.110
J09-J18 Influenza and pneumonia	0.890	0.109
M00-M03 Infectious arthropathies	0.891	0.109
M60-M63 Disorders of muscles	0.891	0.109
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.891	0.109
M40-M43 Deforming dorsopathies	0.891	0.109
J34 Other disorders of nose and nasal sinuses	0.891	0.109
Z84 Family history of other conditions	0.892	0.108
Z81 Family history of mental and behavioural disorders	0.892	0.108
Z89 Acquired absence of limb	0.892	0.108
I60 Subarachnoid haemorrhage	0.892	0.108
Z97 Presence of other devices	0.892	0.108
Z94 Transplanted organ and tissue status	0.892	0.108
Z53 Persons encountering health services for specifie procedures, not carried out	0.892	0.108
I67 Other cerebrovascular diseases	0.892	0.108
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.892	0.108
M15-M19 Arthrosis	0.892	0.108
I63 Cerebral infarction	0.892	0.108
C60-C63 Malignant neoplasms of male genital organs	0.892	0.107
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.892	0.107
D10-D36 Benign neoplasms	0.893	0.107
Z83 Family history of other specific disorders	0.893	0.107
J00-J06 Acute upper respiratory infections	0.893	0.107
Z80 Family history of malignant neoplasm	0.893	0.107
F40-F48 Neurotic, stress-related and somatoform disorders	0.893	0.107
J95-J99 Other diseases of the respiratory system	0.893	0.107
Z98 Other postsurgical states	0.893	0.107
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.894	0.106
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.894	0.106
J90-J94 Other diseases of pleura	0.894	0.106
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.894	0.106
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.894	0.105
Z51 Other medical care	0.894	0.105
J60-J70 Lung diseases due to external agents	0.894	0.105
J80-J84 Other respiratory diseases principally affecting the interstitium	0.895	0.105
R30-R39 Symptoms and signs involving the urinary system	0.895	0.104
G40-G47 Episodic and paroxysmal disorders	0.896	0.104
Z96 Presence of other functional implants	0.896	0.104
K55-K64 Other diseases of intestines	0.896	0.104
A30-A49 Other bacterial diseases	0.896	0.104
Z87 Personal history of other diseases and conditions	0.896	0.103
Z88.6 Personal history of allergy to analgesic agent	0.897	0.103
Z40 Prophylactic surgery	0.897	0.103
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.897	0.103
A00-A09 Intestinal infectious diseases	0.897	0.103
J20-J22 Other acute lower respiratory infections	0.897	0.103
Z43 Attention to artificial openings	0.897	0.103
I62 Other nontraumatic intracranial haemorrhage	0.897	0.103
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.897	0.102
I61 Intracerebral haemorrhage	0.897	0.102
B25-B34 Other viral diseases	0.897	0.102
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.897	0.102
I69 Sequelae of cerebrovascular disease	0.898	0.102
C64-C68 Malignant neoplasms of urinary tract	0.898	0.102
Z45 Adjustment and management of implanted device	0.898	0.102
D00-D09 In situ neoplasms	0.898	0.102
N30-N39 Other diseases of urinary system	0.898	0.102
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.898	0.102
N40-N51 Diseases of male genital organs	0.898	0.102
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.898	0.102
I44 Atrioventricular and left bundle-branch block	0.898	0.102
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.898	0.101
K65-K67 Diseases of peritoneum	0.899	0.101
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.899	0.101
G90-G99 Other disorders of the nervous system	0.899	0.101
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.899	0.101
C40-C41 Malignant neoplasms of bone and articular cartilage	0.899	0.101
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.899	0.101
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.899	0.101
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.899	0.101
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.899	0.101
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.899	0.101
A75-A79 Rickettsioses	0.899	0.101
A70-A74 Other diseases caused by chlamydiae	0.899	0.101
A20-A28 Certain zoonotic bacterial diseases	0.899	0.101
B85-B89 Pediculosis, acariasis and other infestations	0.899	0.101
A65-A69 Other spirochaetal diseases	0.899	0.101
B99-B99 Other infectious diseases	0.899	0.101
B65-B83 Helminthiases	0.899	0.101
B50-B64 Protozoal diseases	0.899	0.101
A15-A19 Tuberculosis	0.899	0.101
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.899	0.101
B20-B24 Human immunodeficiency virus [HIV] disease	0.899	0.101
B90-B94 Sequelae of infectious and parasitic diseases	0.899	0.101
A50-A64 Infections with a predominantly sexual mode of transmission	0.899	0.101
A80-A89 Viral infections of the central nervous system	0.899	0.101
B15-B19 Viral hepatitis	0.899	0.101
F30-F39 Mood [affective] disorders	0.899	0.101
C15-C26 Malignant neoplasms of digestive organs	0.899	0.101
K70-K77 Diseases of liver	0.899	0.101
Z44 Fitting and adjustment of external prosthetic device	0.899	0.100
Z54 Convalescence	0.899	0.100
K50-K52 Noninfective enteritis and colitis	0.899	0.100
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.899	0.100
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.899	0.100
Z52 Donors of organs and tissues	0.899	0.100
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.899	0.100
Z49 Care involving dialysis	0.899	0.100
C51-C58 Malignant neoplasms of female genital organs	0.900	0.100
Z41 Procedures for purposes other than remedying health state	0.900	0.100
Z88.1 Personal history of allergy to other antibiotic agents	0.900	0.100
G70-G73 Diseases of myoneural junction and muscle	0.900	0.100
G00-G09 Inflammatory diseases of the central nervous system	0.900	0.100
R95-R99 Ill-defined and unknown causes of mortality	0.900	0.100
B35-B49 Mycoses	0.900	0.100
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.900	0.100
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.900	0.100
Z48 Other surgical follow-up care	0.900	0.100
I68 Cerebrovascular disorders in diseases classified elsewhere	0.900	0.100
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.900	0.100
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.900	0.100
D37-D48 Neoplasms of uncertain or unknown behaviour	0.900	0.100
D70-D77 Other diseases of blood and blood-forming organs	0.900	0.100
Z42 Follow-up care involving plastic surgery	0.900	0.100
G80-G83 Cerebral palsy and other paralytic syndromes	0.900	0.100
G20-G26 Extrapyramidal and movement disorders	0.900	0.100
S00-S09 Injuries to the head	0.900	0.100
R47-R49 Symptoms and signs involving speech and voice	0.900	0.099
I64 Stroke, not specified as haemorrhage or infarction	0.900	0.099
T36-T50 Poisoning by drugs, medicaments and biological substances	0.901	0.099
Z47 Other orthopaedic follow-up care	0.901	0.099
J32 Chronic sinusitis	0.901	0.099
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.901	0.099
J33 Nasal polyp	0.901	0.099
I51 Complications and ill-defined descriptions of heart disease	0.901	0.099
Z46 Fitting and adjustment of other devices	0.901	0.099
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.901	0.098
Z75 Problems related to medical facilities and other health care	0.901	0.098
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.901	0.098
F70-F79 Mental retardation	0.901	0.098
F99-F99 Unspecified mental disorder	0.902	0.098
F80-F89 Disorders of psychological development	0.902	0.098
F60-F69 Disorders of adult personality and behaviour	0.902	0.098
J40-J47 Chronic lower respiratory diseases	0.902	0.098
I50 Heart failure	0.902	0.098
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.902	0.098
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.902	0.098
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.902	0.098
G30-G32 Other degenerative diseases of the nervous system	0.902	0.098
F00-F09 Organic, including symptomatic, mental disorders	0.902	0.098
M06 Other rheumatoid arthritis	0.902	0.098
Z88.2 Personal history of allergy to sulphonamides	0.902	0.098
Z72 Problems related to lifestyle	0.902	0.098
Z88.5 Personal history of allergy to narcotic agent	0.902	0.098
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.902	0.098
I30 Acute pericarditis	0.902	0.098
G35-G37 Demyelinating diseases of the central nervous system	0.902	0.098
O20-O29 Other maternal disorders predominantly related to pregnancy	0.902	0.097
I42 Cardiomyopathy	0.903	0.097
K35-K38 Diseases of appendix	0.903	0.097
C43-C44 Melanoma and other malignant neoplasms of skin	0.903	0.097
I49 Other cardiac arrhythmias	0.903	0.097
I35 Nonrheumatic aortic valve disorders	0.903	0.097
I34 Nonrheumatic mitral valve disorders	0.903	0.097
K40-K46 Hernia	0.903	0.097
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.903	0.097
D60-D64 Aplastic and other anaemias	0.903	0.096
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.903	0.096
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.903	0.096
O85-O92 Complications predominantly related to the puerperium	0.904	0.096
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.904	0.096
Z74 Problems related to care-provider dependency	0.904	0.096
N60-N64 Disorders of breast	0.904	0.096
K20-K31 Diseases of oesophagus, stomach and duodenum	0.904	0.096
D55-D59 Haemolytic anaemias	0.904	0.096
D50-D53 Nutritional anaemias	0.904	0.095
D80-D89 Certain disorders involving the immune mechanism	0.904	0.095
S40-S49 Injuries to the shoulder and upper arm	0.904	0.095
N20-N23 Urolithiasis	0.905	0.095
N99-N99 Other disorders of the genitourinary system	0.905	0.095
G50-G59 Nerve, nerve root and plexus disorders	0.905	0.095
M75 Shoulder lesions	0.905	0.095
N00-N08 Glomerular diseases	0.905	0.095
I52 Other heart disorders in diseases classified elsewhere	0.905	0.095
I48 Atrial fibrillation and flutter	0.905	0.095
I43 Cardiomyopathy in diseases classified elsewhere	0.905	0.095
I41 Myocarditis in diseases classified elsewhere	0.905	0.095
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.905	0.095
I32 Pericarditis in diseases classified elsewhere	0.905	0.095
I40 Acute myocarditis	0.905	0.095
I37 Pulmonary valve disorders	0.905	0.095
I36 Nonrheumatic tricuspid valve disorders	0.905	0.095
I33 Acute and subacute endocarditis	0.905	0.095
N25-N29 Other disorders of kidney and ureter	0.905	0.095
S50-S59 Injuries to the elbow and forearm	0.905	0.095
I38 Endocarditis, valve unspecified	0.905	0.095
T33-T35 Frostbite	0.905	0.095
T26-T28 Burns and corrosions confined to eye and internal organs	0.905	0.095
T00-T07 Injuries involving multiple body regions	0.905	0.095
I46 Cardiac arrest	0.905	0.095
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.905	0.094
N80-N98 Noninflammatory disorders of female genital tract	0.905	0.094
K90-K93 Other diseases of the digestive system	0.905	0.094
T79-T79 Certain early complications of trauma	0.905	0.094
N17-N19 Renal failure	0.905	0.094
I31 Other diseases of pericardium	0.905	0.094
T20-T25 Burns and corrosions of external body surface, specified by site	0.905	0.094
S10-S19 Injuries to the neck	0.905	0.094
T15-T19 Effects of foreign body entering through natural orifice	0.905	0.094
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.905	0.094
Z88.7 Personal history of allergy to serum and vaccine	0.905	0.094
T66-T78 Other and unspecified effects of external causes	0.906	0.094
Z88.4 Personal history of allergy to anaesthetic agent	0.906	0.094
Z88.3 Personal history of allergy to other anti-infective agents	0.906	0.094
S90-S99 Injuries to the ankle and foot	0.906	0.094
N10-N16 Renal tubulo-interstitial diseases	0.906	0.094
I45 Other conduction disorders	0.906	0.094
S70-S79 Injuries to the hip and thigh	0.906	0.094
S20-S29 Injuries to the thorax	0.906	0.094
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.906	0.094
I10 Essential (primary) hypertension	0.906	0.094
O94-O99 Other obstetric conditions, not elsewhere classified	0.906	0.094
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.906	0.094
Z88.0 Personal history of allergy to penicillin	0.906	0.094
N70-N77 Inflammatory diseases of female pelvic organs	0.906	0.094
I47 Paroxysmal tachycardia	0.906	0.094
O80-O84 Delivery	0.906	0.094
O60-O75 Complications of labour and delivery	0.906	0.093
O00-O08 Pregnancy with abortive outcome	0.906	0.093
Z70 Counselling related to sexual attitude, behaviour and orientation	0.906	0.093
Z76 Persons encountering health services in other circumstances	0.907	0.093
Z73 Problems related to life-management difficulty	0.907	0.093
S80-S89 Injuries to the knee and lower leg	0.907	0.093
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.907	0.093
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.907	0.093
Q20-Q28 Congenital malformations of the circulatory system	0.907	0.093
S60-S69 Injuries to the wrist and hand	0.907	0.092
E70-E90 Metabolic disorders	0.908	0.092
J37 Chronic laryngitis and laryngotracheitis	0.908	0.092
J36 Peritonsillar abscess	0.908	0.092
J39 Other diseases of upper respiratory tract	0.908	0.092
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.908	0.092
J35 Chronic diseases of tonsils and adenoids	0.908	0.092
Z03 Medical observation and evaluation for suspected diseases and conditions	0.908	0.092
J30 Vasomotor and allergic rhinitis	0.908	0.092
L00-L08 Infections of the skin and subcutaneous tissue	0.908	0.091
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.908	0.091
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.908	0.091
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.909	0.091
Q35-Q37 Cleft lip and cleft palate	0.909	0.091
Q30-Q34 Congenital malformations of the respiratory system	0.909	0.091
Q00-Q07 Congenital malformations of the nervous system	0.909	0.091
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.909	0.091
Q80-Q89 Other congenital malformations	0.909	0.091
Q50-Q56 Congenital malformations of genital organs	0.909	0.091
Q38-Q45 Other congenital malformations of the digestive system	0.909	0.091
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.909	0.091
Q60-Q64 Congenital malformations of the urinary system	0.909	0.091
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.909	0.091
Z08 Follow-up examination after treatment for malignant neoplasm	0.909	0.091
P90-P96 Other disorders originating in the perinatal period	0.909	0.091
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.909	0.091
P75-P78 Digestive system disorders of fetus and newborn	0.909	0.091
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.909	0.091
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.909	0.091
P35-P39 Infections specific to the perinatal period	0.909	0.091
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.909	0.091
P10-P15 Birth trauma	0.909	0.091
P05-P08 Disorders related to length of gestation and fetal growth	0.909	0.091
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.909	0.091
H65-H75 Diseases of middle ear and mastoid	0.909	0.090
Z86.4 Personal history of psychoactive substance abuse	0.910	0.090
Z11 Special screening examination for infectious and parasitic diseases	0.910	0.090
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.910	0.090
L20-L30 Dermatitis and eczema	0.910	0.090
C50 Malignant neoplasm of breast	0.910	0.090
E40-E46 Malnutrition	0.910	0.090
I22 Subsequent myocardial infarction	0.910	0.090
Z22 Carrier of infectious disease	0.910	0.090
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.910	0.090
I24 Other acute ischaemic heart diseases	0.910	0.089
E50-E64 Other nutritional deficiencies	0.910	0.089
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.910	0.089
H60-H62 Diseases of external ear	0.911	0.089
Z86.6 Personal history of diseases of the nervous system and sense organs	0.911	0.089
W00-W19 Falls	0.911	0.089
H80-H83 Diseases of inner ear	0.911	0.089
E00-E07 Disorders of thyroid gland	0.911	0.089
E20-E35 Disorders of other endocrine glands	0.911	0.089
E10-E14 Diabetes mellitus	0.911	0.089
R10 Abdominal and pelvic pain	0.911	0.089
I25 Chronic ischaemic heart disease	0.911	0.089
E65-E68 Obesity and other hyperalimentation	0.911	0.089
L10-L14 Bullous disorders	0.911	0.089
Y35-Y36 Legal intervention and operations of war	0.911	0.089
X85-X99 Assault	0.911	0.089
X30-X39 Exposure to forces of nature	0.911	0.089
W65-W74 Accidental drowning and submersion	0.911	0.089
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.911	0.089
Y10-Y34 Event of undetermined intent	0.911	0.089
X00-X09 Exposure to smoke, fire and flames	0.911	0.089
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.911	0.089
V98-V99 Other and unspecified transport accidents	0.911	0.089
V95-V97 Air and space transport accidents	0.911	0.089
V90-V94 Water transport accidents	0.911	0.089
V70-V79 Bus occupant injured in transport accident	0.911	0.089
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.911	0.089
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.911	0.089
X20-X29 Contact with venomous animals and plants	0.911	0.089
X10-X19 Contact with heat and hot substances	0.911	0.089
W75-W84 Other accidental threats to breathing	0.911	0.089
V01-V09 Pedestrian injured in transport accident	0.911	0.089
Y00-Y09 Assault	0.911	0.089
X58-X59 Accidental exposure to other and unspecified factors	0.911	0.088
X50-X57 Overexertion, travel and privation	0.911	0.088
V80-V89 Other land transport accidents	0.911	0.088
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.911	0.088
X40-X49 Accidental poisoning by and exposure to noxious substances	0.911	0.088
V40-V49 Car occupant injured in transport accident	0.911	0.088
L50-L54 Urticaria and erythema	0.911	0.088
V20-V29 Motorcycle rider injured in transport accident	0.911	0.088
W50-W64 Exposure to animate mechanical forces	0.911	0.088
Y60-Y69 Misadventures to patients during surgical and medical care	0.911	0.088
X60-X84 Intentional self-harm	0.911	0.088
V10-V19 Pedal cyclist injured in transport accident	0.911	0.088
H90-H95 Other disorders of ear	0.911	0.088
Z86.7 Personal history of diseases of the circulatory system	0.911	0.088
M70 Soft tissue disorders related to use, overuse and pressure	0.912	0.088
M77 Other enthesopathies	0.912	0.088
W20-W49 Exposure to inanimate mechanical forces	0.912	0.088
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.912	0.088
I20 Angina pectoris	0.912	0.088
L40-L45 Papulosquamous disorders	0.912	0.088
Z13 Special screening examination for other diseases and disorders	0.912	0.088
Z10 Routine general health check-up of defined subpopulation	0.912	0.088
M79 Other soft tissue disorders, not elsewhere classified	0.912	0.088
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.912	0.087
Z28 Immunisation not carried out	0.912	0.087
Z27 Need for immunisation against combinations of infectious diseases	0.912	0.087
Z26 Need for immunisation against other single infectious diseases	0.912	0.087
Z25 Need for immunisation against other single viral diseases	0.912	0.087
Z24 Need for immunisation against certain single viral diseases	0.912	0.087
Z23 Need for immunisation against single bacterial diseases	0.912	0.087
Z36 Antenatal screening	0.912	0.087
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.912	0.087
Z20 Contact with and exposure to communicable diseases	0.912	0.087
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.912	0.087
I23 Certain current complications following acute myocardial infarction	0.913	0.087
I21 Acute myocardial infarction	0.913	0.087
I13 Hypertensive heart and renal disease	0.913	0.087
I15 Secondary hypertension	0.913	0.087
Z04 Examination and observation for other reasons	0.913	0.087
Z29 Need for other prophylactic measures	0.913	0.087
I11 Hypertensive heart disease	0.913	0.087
Z02 Examination and encounter for administrative purposes	0.913	0.087
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.913	0.087
I12 Hypertensive renal disease	0.913	0.087
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.913	0.087
M35 Other systemic involvement of connective tissue	0.913	0.087
M73 Soft tissue disorders in diseases classified elsewhere	0.913	0.087
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.913	0.087
I74 Arterial embolism and thrombosis	0.913	0.086
M76 Enthesopathies of lower limb, excluding foot	0.913	0.086
M71 Other bursopathies	0.913	0.086
M09 Juvenile arthritis in diseases classified elsewhere	0.913	0.086
M08 Juvenile arthritis	0.913	0.086
M12 Other specific arthropathies	0.913	0.086
J34.3 Hypertrophy of nasal turbinates	0.914	0.086
M14 Arthropathies in other diseases classified elsewhere	0.914	0.086
Z92.2 Personal history of long-term (current) use of other medicaments	0.914	0.086
Z90.7 Acquired absence of genital organ(s)	0.914	0.086
M13 Other arthritis	0.914	0.086
M11 Other crystal arthropathies	0.914	0.086
L60-L75 Disorders of skin appendages	0.914	0.086
M07 Psoriatic and enteropathic arthropathies	0.914	0.086
M05 Seropositive rheumatoid arthritis	0.914	0.086
Z86.0 Personal history of other neoplasms	0.914	0.086
M72 Fibroblastic disorders	0.914	0.086
J34.8 Other specified disorders of nose and nasal sinuses	0.914	0.086
L80-L99 Other disorders of the skin and subcutaneous tissue	0.914	0.086
Z50.1 Other physical therapy	0.914	0.086
I95 Hypotension	0.914	0.086
M10 Gout	0.914	0.086
I73 Other peripheral vascular diseases	0.914	0.086
Z12 Special screening examination for neoplasms	0.914	0.086
F41 Other anxiety disorders	0.914	0.086
I63.9 Cerebral infarction, unspecified	0.915	0.085
K80 Cholelithiasis	0.915	0.085
Z38 Liveborn infants according to place of birth	0.915	0.085
Z32 Pregnancy examination and test	0.915	0.085
Z37 Outcome of delivery	0.915	0.085
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.915	0.085
Z31 Procreative management	0.915	0.085
Z39 Postpartum care and examination	0.915	0.085
Z33 Pregnant state, incidental	0.915	0.085
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.915	0.085
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.915	0.085
Z34 Supervision of normal pregnancy	0.915	0.085
Z35 Supervision of high-risk pregnancy	0.915	0.085
I99 Other and unspecified disorders of circulatory system	0.915	0.085
I98 Other disorders of circulatory system in diseases classified elsewhere	0.915	0.085
Z62 Other problems related to upbringing	0.915	0.085
Z55 Problems related to education and literacy	0.915	0.085
Z65 Problems related to other psychosocial circumstances	0.915	0.085
Z64 Problems related to certain psychosocial circumstances	0.915	0.085
Z61 Problems related to negative life events in childhood	0.915	0.085
Z59 Problems related to housing and economic circumstances	0.915	0.085
Z58 Problems related to physical environment	0.915	0.085
Z56 Problems related to employment and unemployment	0.915	0.085
Z86.5 Personal history of other mental and behavioural disorders	0.915	0.085
Z63 Other problems related to primary support group, including family circumstances	0.915	0.085
I26 Pulmonary embolism	0.915	0.085
Z57 Occupational exposure to risk-factors	0.915	0.085
M22 Disorders of patella	0.915	0.084
Z90.1 Acquired absence of breast(s)	0.915	0.084
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.916	0.084
Z86.1 Personal history of infectious and parasitic diseases	0.916	0.084
I70 Atherosclerosis	0.916	0.084
I72 Other aneurysm	0.916	0.084
I78 Diseases of capillaries	0.916	0.084
M48 Other spondylopathies	0.916	0.084
Z85.3 Personal history of malignant neoplasm of breast	0.916	0.084
I77 Other disorders of arteries and arterioles	0.916	0.084
M21 Other acquired deformities of limbs	0.916	0.084
I71 Aortic aneurysm and dissection	0.916	0.084
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.916	0.084
Z60 Problems related to social environment	0.916	0.084
Z50.5 Speech therapy	0.916	0.084
C61 Malignant neoplasm of prostate	0.916	0.084
M20 Acquired deformities of fingers and toes	0.916	0.083
I28 Other diseases of pulmonary vessels	0.916	0.083
Z91.5 Personal history of self-harm	0.916	0.083
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.917	0.083
I67.1 Cerebral aneurysm, nonruptured	0.917	0.083
I27 Other pulmonary heart diseases	0.917	0.083
M46 Other inflammatory spondylopathies	0.917	0.083
Z90.4 Acquired absence of other parts of digestive tract	0.917	0.083
J18 Pneumonia, organism unspecified	0.917	0.083
D25 Leiomyoma of uterus	0.917	0.083
I02 Rheumatic chorea	0.917	0.083
I01 Rheumatic fever with heart involvement	0.917	0.083
I00 Rheumatic fever without mention of heart involvement	0.917	0.083
Z30 Contraceptive management	0.917	0.083
R13 Dysphagia	0.917	0.083
J34.2 Deviated nasal septum	0.917	0.083
Z99.3 Dependence on wheelchair	0.917	0.083
Z85.5 Personal history of malignant neoplasm of urinary tract	0.917	0.082
M81 Osteoporosis without pathological fracture	0.917	0.082
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.917	0.082

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations