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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80299072
log Bayes Factor = 15.8593
Chromosome 8   position 36,556,762  (GRCh37) Explore rs80299072 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
M15-M19 Arthrosis
0.993 0.007 0.000
M19 Other arthrosis
0.993 0.007 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
M20-M25 Other joint disorders
0.988 0.012 0.000
R50-R69 General symptoms and signs
0.984 0.016 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.984 0.016 0.000
M19.9 Arthrosis, unspecified
0.983 0.017 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.979 0.021 0.000
M20 Acquired deformities of fingers and toes
0.978 0.022 0.000
M50-M54 Other dorsopathies
0.976 0.024 0.000
R51 Headache
0.975 0.025 0.000
M19.0 Primary arthrosis of other joints
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.974 0.026 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
N73 Other female pelvic inflammatory diseases
0.972 0.028 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.971 0.029 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.969 0.031 0.000
M54 Dorsalgia
0.966 0.034 0.000
N73.6 Female pelvic peritoneal adhesions
0.964 0.036 0.000
Z50 Care involving use of rehabilitation procedures
0.963 0.037 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.961 0.039 0.000
E70-E90 Metabolic disorders
0.959 0.041 0.000
G40-G47 Episodic and paroxysmal disorders
0.956 0.044 0.000
Chapter X Diseases of the respiratory system
0.956 0.044 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.953 0.047 0.000
R59 Enlarged lymph nodes
0.951 0.049 0.000
R42 Dizziness and giddiness
0.951 0.049 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.948 0.052 0.000
Chapter II Neoplasms
0.938 0.062 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.935 0.065 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.934 0.066 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.932 0.068 0.000
N17-N19 Renal failure
0.930 0.070 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.929 0.071 0.000
M54.2 Cervicalgia
0.928 0.072 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.926 0.074 0.000
M45-M49 Spondylopathies
0.922 0.078 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.918 0.082 0.000
Z50.1 Other physical therapy
0.918 0.082 0.000
Chapter VII Diseases of the eye and adnexa
0.916 0.084 0.000
R59.0 Localised enlarged lymph nodes
0.916 0.084 0.000
N30-N39 Other diseases of urinary system
0.915 0.085 0.000
M20.1 Hallux valgus (acquired)
0.914 0.086 0.000
M20.4 Other hammer toe(s) (acquired)
0.913 0.087 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.912 0.088 0.000
Y86 Sequelae of other accidents
0.911 0.089 0.000
G40 Epilepsy
0.911 0.089 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.909 0.091 0.000
M54.5 Low back pain
0.906 0.094 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.904 0.096 0.000
Chapter I Certain infectious and parasitic diseases
0.901 0.099 0.000
M54.22 Cervicalgia (Cervical region)
0.900 0.100 0.000
J90-J94 Other diseases of pleura
0.900 0.100 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.899 0.101 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.897 0.103 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.895 0.105 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.892 0.108 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.891 0.109 0.000
M05-M14 Inflammatory polyarthropathies
0.886 0.114 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.885 0.115 0.000
Z46 Fitting and adjustment of other devices
0.885 0.115 0.000
M47 Spondylosis
0.882 0.118 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.882 0.118 0.000
M19.94 Arthrosis, unspecified (Hand)
0.880 0.120 0.000
W20-W49 Exposure to inanimate mechanical forces
0.877 0.123 0.000
G47 Sleep disorders
0.876 0.124 0.000
G40.9 Epilepsy, unspecified
0.870 0.130 0.000
C79 Secondary malignant neoplasm of other sites
0.869 0.131 0.000
S60-S69 Injuries to the wrist and hand
0.868 0.132 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.868 0.132 0.000
J95-J99 Other diseases of the respiratory system
0.863 0.137 0.000
Z50.0 Cardiac rehabilitation
0.863 0.137 0.000
M20.5 Other deformities of toe(s) (acquired)
0.857 0.143 0.000
N30 Cystitis
0.856 0.144 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.854 0.146 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.853 0.147 0.000
N60-N64 Disorders of breast
0.853 0.147 0.000
Chapter V Mental and behavioural disorders
0.850 0.150 0.000
R41.0 Disorientation, unspecified
0.850 0.150 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.848 0.152 0.000
N18 Chronic renal failure
0.847 0.153 0.000
Z50.5 Speech therapy
0.844 0.156 0.000
M19.98 Arthrosis, unspecified (Other)
0.843 0.157 0.000
M47.8 Other spondylosis
0.841 0.159 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.835 0.165 0.000
E65-E68 Obesity and other hyperalimentation
0.834 0.166 0.000
H53-H54 Visual disturbances and blindness
0.832 0.168 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.832 0.168 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.829 0.171 0.000
N20-N23 Urolithiasis
0.829 0.171 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.828 0.172 0.000
D00-D09 In situ neoplasms
0.825 0.175 0.000
Z46.6 Fitting and adjustment of urinary device
0.825 0.175 0.000
E86 Volume depletion
0.823 0.177 0.000
C77.3 Axillary and upper limb lymph nodes
0.821 0.179 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.820 0.180 0.000
G47.3 Sleep apnoea
0.817 0.183 0.000
R59.1 Generalised enlarged lymph nodes
0.816 0.184 0.000
T93 Sequelae of injuries of lower limb
0.815 0.185 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.815 0.185 0.000
N19 Unspecified renal failure
0.815 0.185 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.813 0.187 0.000
M35 Other systemic involvement of connective tissue
0.811 0.188 0.000
H55-H59 Other disorders of eye and adnexa
0.811 0.189 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.809 0.191 0.000
B25-B34 Other viral diseases
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.806 0.193 0.000
G43 Migraine
0.806 0.194 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.806 0.194 0.000
E87.2 Acidosis
0.804 0.196 0.000
J98 Other respiratory disorders
0.803 0.197 0.000
M25 Other joint disorders, not elsewhere classified
0.802 0.198 0.000
E88 Other metabolic disorders
0.802 0.198 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.801 0.199 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.801 0.199 0.000
M40-M43 Deforming dorsopathies
0.800 0.200 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.798 0.202 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.796 0.204 0.000
Z95.4 Presence of other heart-valve replacement
0.794 0.206 0.000
M54.57 Low back pain (Lumbosacral region)
0.793 0.207 0.000
R58 Haemorrhage, not elsewhere classified
0.792 0.208 0.000
W22 Striking against or struck by other objects
0.792 0.208 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.792 0.208 0.000
M19.1 Posttraumatic arthrosis of other joints
0.791 0.208 0.000
N32 Other disorders of bladder
0.791 0.209 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.791 0.209 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.790 0.210 0.000
B95-B98 Bacterial, viral and other infectious agents
0.788 0.212 0.000
N30.8 Other cystitis
0.788 0.212 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.787 0.213 0.000
N18.9 Chronic renal failure, unspecified
0.785 0.215 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.784 0.216 0.000
T91 Sequelae of injuries of neck and trunk
0.783 0.217 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.782 0.218 0.000
N76 Other inflammation of vagina and vulva
0.781 0.219 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.780 0.220 0.000
M47.86 Other spondylosis (Lumbar region)
0.780 0.220 0.000
W00-W19 Falls
0.780 0.220 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.780 0.220 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.778 0.222 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.778 0.222 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.777 0.223 0.000
E89.0 Postprocedural hypothyroidism
0.777 0.223 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.777 0.223 0.000
E73 Lactose intolerance
0.776 0.224 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.776 0.224 0.000
J93 Pneumothorax
0.776 0.224 0.000
M20.2 Hallux rigidus
0.775 0.225 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.772 0.228 0.000
Z45 Adjustment and management of implanted device
0.771 0.229 0.000
R52 Pain, not elsewhere classified
0.771 0.229 0.000
R94 Abnormal results of function studies
0.770 0.230 0.000
Z95.2 Presence of prosthetic heart valve
0.770 0.230 0.000
R47-R49 Symptoms and signs involving speech and voice
0.769 0.231 0.000
S50-S59 Injuries to the elbow and forearm
0.767 0.233 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.764 0.236 0.000
J92 Pleural plaque
0.762 0.238 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.762 0.238 0.000
Z93 Artificial opening status
0.760 0.240 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.760 0.240 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.759 0.241 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.757 0.243 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.755 0.245 0.000
Z97 Presence of other devices
0.751 0.249 0.000
V80-V89 Other land transport accidents
0.751 0.249 0.000
N32.3 Diverticulum of bladder
0.751 0.249 0.000
G70-G73 Diseases of myoneural junction and muscle
0.750 0.250 0.000
N35 Urethral stricture
0.748 0.251 0.000
Y83.8 Other surgical procedures
0.748 0.252 0.000
J90 Pleural effusion, not elsewhere classified
0.748 0.252 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.747 0.253 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.747 0.253 0.000
Y85 Sequelae of transport accidents
0.746 0.254 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.745 0.255 0.000
N20 Calculus of kidney and ureter
0.745 0.255 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.745 0.255 0.000
A30-A49 Other bacterial diseases
0.743 0.257 0.000
B34 Viral infection of unspecified site
0.742 0.258 0.000
N71 Inflammatory disease of uterus, except cervix
0.742 0.258 0.000
Z90.3 Acquired absence of part of stomach
0.742 0.258 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.741 0.259 0.000
E87.7 Fluid overload
0.740 0.260 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.739 0.261 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.739 0.261 0.000
E83 Disorders of mineral metabolism
0.738 0.262 0.000
Z49 Care involving dialysis
0.737 0.263 0.000
R57 Shock, not elsewhere classified
0.737 0.263 0.000
M54.6 Pain in thoracic spine
0.737 0.263 0.000
T92 Sequelae of injuries of upper limb
0.737 0.263 0.000
G44 Other headache syndromes
0.736 0.264 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.736 0.264 0.000
E66 Obesity
0.735 0.265 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.734 0.266 0.000
M54.59 Low back pain (Site unspecified)
0.733 0.267 0.000
W22.9 Unspecified place
0.731 0.269 0.000
Chapter XXII Codes for special purposes
0.730 0.270 0.000
M31 Other necrotising vasculopathies
0.729 0.271 0.000
M24 Other specific joint derangements
0.727 0.273 0.000
J98.4 Other disorders of lung
0.727 0.273 0.000
E87.5 Hyperkalaemia
0.727 0.273 0.000
G82 Paraplegia and tetraplegia
0.725 0.275 0.000
H54 Blindness and low vision
0.724 0.276 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.724 0.276 0.000
Z50.2 Alcohol rehabilitation
0.723 0.277 0.000
S60 Superficial injury of wrist and hand
0.723 0.277 0.000
Z51 Other medical care
0.723 0.277 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.722 0.278 0.000
H55 Nystagmus and other irregular eye movements
0.722 0.278 0.000
M86-M90 Other osteopathies
0.721 0.279 0.000
M53 Other dorsopathies, not elsewhere classified
0.721 0.279 0.000
J60-J70 Lung diseases due to external agents
0.719 0.281 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.719 0.281 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.718 0.282 0.000
M54.4 Lumbago with sciatica
0.717 0.282 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
X60-X84 Intentional self-harm
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
M54.9 Dorsalgia, unspecified
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.716 0.284 0.000
N60 Benign mammary dysplasia
0.715 0.285 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.286 0.000
S80-S89 Injuries to the knee and lower leg
0.713 0.287 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.287 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.287 0.000
N61 Inflammatory disorders of breast
0.712 0.288 0.000
M15 Polyarthrosis
0.712 0.288 0.000
M19.8 Other specified arthrosis
0.712 0.288 0.000
M19.2 Other secondary arthrosis
0.712 0.288 0.000
M21 Other acquired deformities of limbs
0.711 0.289 0.000
T93.2 Sequelae of other fractures of lower limb
0.711 0.289 0.000
E20-E35 Disorders of other endocrine glands
0.710 0.289 0.000
N99-N99 Other disorders of the genitourinary system
0.710 0.290 0.000
M13 Other arthritis
0.710 0.290 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.710 0.290 0.000
J84 Other interstitial pulmonary diseases
0.710 0.290 0.000
Z41 Procedures for purposes other than remedying health state
0.710 0.290 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.709 0.291 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
M34 Systemic sclerosis
0.708 0.292 0.000
M33 Dermatopolymyositis
0.708 0.292 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.708 0.292 0.000
Z82.3 Family history of stroke
0.708 0.292 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.707 0.292 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.707 0.293 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.707 0.293 0.000
Z50.8 Care involving use of rehabilitation procedures
0.706 0.294 0.000
R68 Other general symptoms and signs
0.705 0.294 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.705 0.294 0.000
R62 Lack of expected normal physiological development
0.705 0.294 0.000
R64 Cachexia
0.705 0.294 0.000
R46 Symptoms and signs involving appearance and behaviour
0.705 0.295 0.000
R45 Symptoms and signs involving emotional state
0.705 0.295 0.000
R43 Disturbances of smell and taste
0.705 0.295 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.705 0.295 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.705 0.295 0.000
D69 Purpura and other haemorrhagic conditions
0.705 0.295 0.000
N64 Other disorders of breast
0.704 0.296 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.702 0.298 0.000
M10 Gout
0.701 0.299 0.000
R56 Convulsions, not elsewhere classified
0.701 0.299 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.701 0.299 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.701 0.299 0.000
H53 Visual disturbances
0.700 0.299 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.700 0.300 0.000
G43.9 Migraine, unspecified
0.700 0.300 0.000
M19.08 Primary arthrosis of other joints (Other)
0.699 0.301 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.699 0.301 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.699 0.301 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.699 0.301 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.699 0.301 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.699 0.301 0.000
S20-S29 Injuries to the thorax
0.698 0.302 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.698 0.302 0.000
E87.3 Alkalosis
0.698 0.302 0.000
E40-E46 Malnutrition
0.697 0.303 0.000
M07 Psoriatic and enteropathic arthropathies
0.697 0.303 0.000
M20.3 Other deformity of hallux (acquired)
0.697 0.303 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.697 0.303 0.000
N73.5 Female pelvic peritonitis, unspecified
0.697 0.303 0.000
N73.4 Female chronic pelvic peritonitis
0.697 0.303 0.000
N73.3 Female acute pelvic peritonitis
0.697 0.303 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.697 0.303 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.697 0.303 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.697 0.303 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.696 0.304 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.696 0.304 0.000
G30-G32 Other degenerative diseases of the nervous system
0.696 0.304 0.000
N30.1 Interstitial cystitis (chronic)
0.695 0.305 0.000
B34.9 Viral infection, unspecified
0.695 0.305 0.000
Z54 Convalescence
0.695 0.305 0.000
Z52 Donors of organs and tissues
0.695 0.305 0.000
Z44 Fitting and adjustment of external prosthetic device
0.695 0.305 0.000
Z95.0 Presence of cardiac pacemaker
0.695 0.305 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.695 0.305 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.694 0.306 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.693 0.306 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.693 0.306 0.000
G90-G99 Other disorders of the nervous system
0.693 0.307 0.000
E00-E07 Disorders of thyroid gland
0.693 0.307 0.000
M54.8 Other dorsalgia
0.693 0.307 0.000
M54.0 Panniculitis affecting regions of neck and back
0.693 0.307 0.000
Z50.6 Orthoptic training
0.690 0.310 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.690 0.310 0.000
Z50.3 Drug rehabilitation
0.690 0.310 0.000
D09 Carcinoma in situ of other and unspecified sites
0.689 0.311 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.689 0.311 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.689 0.311 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.689 0.311 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.689 0.311 0.000
T83.2 Mechanical complication of graft of urinary organ
0.689 0.311 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.689 0.311 0.000
M80-M85 Disorders of bone density and structure
0.688 0.312 0.000
N70 Salpingitis and oophoritis
0.688 0.312 0.000
N30.9 Cystitis, unspecified
0.688 0.312 0.000
E85 Amyloidosis
0.687 0.312 0.000
E84 Cystic fibrosis
0.687 0.312 0.000
E79 Disorders of purine and pyrimidine metabolism
0.687 0.312 0.000
E77 Disorders of glycoprotein metabolism
0.687 0.312 0.000
E76 Disorders of glycosaminoglycan metabolism
0.687 0.312 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.687 0.312 0.000
E74 Other disorders of carbohydrate metabolism
0.687 0.312 0.000
E72 Other disorders of amino-acid metabolism
0.687 0.312 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.687 0.312 0.000
E70 Disorders of aromatic amino-acid metabolism
0.687 0.312 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.687 0.312 0.000
M46 Other inflammatory spondylopathies
0.687 0.313 0.000
V10-V19 Pedal cyclist injured in transport accident
0.686 0.314 0.000
R54 Senility
0.686 0.314 0.000
C78.2 Secondary malignant neoplasm of pleura
0.686 0.314 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.686 0.314 0.000
G41 Status epilepticus
0.686 0.314 0.000
M47.9 Spondylosis, unspecified
0.685 0.315 0.000
Z83 Family history of other specific disorders
0.685 0.315 0.000
C77.4 Inguinal and lower limb lymph nodes
0.685 0.315 0.000
R61 Hyperhidrosis
0.684 0.315 0.000
Y89 Sequelae of other external causes
0.683 0.316 0.000
Y88 Sequelae of surgical and medical care as external cause
0.683 0.316 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.683 0.316 0.000
N40-N51 Diseases of male genital organs
0.684 0.316 0.000
Z93.6 Other artificial openings of urinary tract status
0.683 0.317 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.683 0.317 0.000
D68 Other coagulation defects
0.683 0.317 0.000
Z96 Presence of other functional implants
0.681 0.319 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.681 0.319 0.000
Z90.1 Acquired absence of breast(s)
0.681 0.319 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.680 0.319 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.680 0.320 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.679 0.321 0.000
C79.2 Secondary malignant neoplasm of skin
0.678 0.322 0.000
N20.1 Calculus of ureter
0.677 0.323 0.000
M06 Other rheumatoid arthritis
0.676 0.324 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.675 0.325 0.000
T66-T78 Other and unspecified effects of external causes
0.675 0.325 0.000
R90.0 Intracranial space-occupying lesion
0.674 0.326 0.000
M35.0 Sicca syndrome [Sjogren]
0.674 0.326 0.000
S61 Open wound of wrist and hand
0.674 0.326 0.000
S00-S09 Injuries to the head
0.673 0.326 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.673 0.327 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.673 0.327 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.673 0.327 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.672 0.328 0.000
G81 Hemiplegia
0.671 0.329 0.000
R40 Somnolence, stupor and coma
0.671 0.329 0.000
Z47 Other orthopaedic follow-up care
0.671 0.329 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.671 0.329 0.000
J92.0 Pleural plaque with presence of asbestos
0.671 0.329 0.000
C50-C50 Malignant neoplasm of breast
0.671 0.329 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.670 0.330 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.670 0.330 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.670 0.330 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.670 0.330 0.000
M54.3 Sciatica
0.670 0.330 0.000
T98 Sequelae of other and unspecified effects of external causes
0.668 0.332 0.000
T95 Sequelae of burns, corrosions and frostbite
0.668 0.332 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.668 0.332 0.000
T90 Sequelae of injuries of head
0.668 0.332 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.668 0.332 0.000
Z57 Occupational exposure to risk-factors
0.668 0.332 0.000
M47.2 Other spondylosis with radiculopathy
0.667 0.333 0.000
Z51.2 Other chemotherapy
0.667 0.333 0.000
Z89 Acquired absence of limb
0.666 0.334 0.000
Z84 Family history of other conditions
0.666 0.334 0.000
Z81 Family history of mental and behavioural disorders
0.666 0.334 0.000
H10-H13 Disorders of conjunctiva
0.666 0.334 0.000
M54.29 Cervicalgia-Site unspe
0.665 0.335 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.665 0.335 0.000
M54.27 Cervicalgia-Lumbosacral
0.665 0.335 0.000
M54.26 Cervicalgia-Lumbar
0.665 0.335 0.000
M54.25 Cervicalgia-Thoracolumbar
0.665 0.335 0.000
M54.24 Cervicalgia-Thoracic
0.665 0.335 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.665 0.335 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.665 0.335 0.000
M54.20 Cervicalgia-Mult site
0.665 0.335 0.000
C80 Malignant neoplasm without specification of site
0.665 0.335 0.000
S69 Other and unspecified injuries of wrist and hand
0.664 0.336 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.664 0.336 0.000
M20.0 Deformity of finger(s)
0.664 0.336 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.664 0.336 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.664 0.336 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.663 0.337 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.663 0.337 0.000
J93.8 Other pneumothorax
0.663 0.337 0.000
Z90.0 Acquired absence of part of head and neck
0.662 0.338 0.000
D50-D53 Nutritional anaemias
0.662 0.338 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.662 0.338 0.000
M65-M68 Disorders of synovium and tendon
0.662 0.338 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.662 0.338 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.662 0.338 0.000
M49 Spondylopathies in diseases classified elsewhere
0.661 0.339 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.661 0.339 0.000
N25-N29 Other disorders of kidney and ureter
0.660 0.340 0.000
S72 Fracture of femur
0.660 0.340 0.000
R55 Syncope and collapse
0.660 0.340 0.000
M18 Arthrosis of first carpometacarpal joint
0.659 0.341 0.000
M25.5 Pain in joint
0.659 0.341 0.000
Z40 Prophylactic surgery
0.659 0.341 0.000
C51-C58 Malignant neoplasms of female genital organs
0.659 0.341 0.000
D80-D89 Certain disorders involving the immune mechanism
0.659 0.341 0.000
Y83.5 Amputation of limb(s)
0.658 0.342 0.000
Y83.0 Surgical operation with transplant of whole organ
0.658 0.342 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.657 0.343 0.000
C77.5 Intrapelvic lymph nodes
0.657 0.343 0.000
N18.5 Chronic kidney disease, stage 5
0.657 0.343 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.657 0.343 0.000
Z80 Family history of malignant neoplasm
0.656 0.344 0.000
N21 Calculus of lower urinary tract
0.656 0.344 0.000
N36 Other disorders of urethra
0.656 0.344 0.000
N37 Urethral disorders in diseases classified elsewhere
0.656 0.344 0.000
N34 Urethritis and urethral syndrome
0.656 0.344 0.000
N33 Bladder disorders in diseases classified elsewhere
0.656 0.344 0.000
M50 Cervical disk disorders
0.655 0.344 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.655 0.344 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.654 0.346 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.654 0.346 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.654 0.346 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.654 0.346 0.000
Z82.2 Family history of deafness and hearing loss
0.654 0.346 0.000
Z82.1 Family history of blindness and visual loss
0.654 0.346 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.654 0.346 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.653 0.347 0.000
G40.8 Other epilepsy
0.653 0.347 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.653 0.347 0.000
G40.5 Special epileptic syndromes
0.653 0.347 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.653 0.347 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.653 0.347 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.653 0.347 0.000
H40-H42 Glaucoma
0.652 0.348 0.000
N10-N16 Renal tubulo-interstitial diseases
0.652 0.348 0.000
C77.8 Lymph nodes of multiple regions
0.651 0.349 0.000
R80 Isolated proteinuria
0.651 0.349 0.000
R60 Oedema, not elsewhere classified
0.651 0.349 0.000
J09-J18 Influenza and pneumonia
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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