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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1059611
log Bayes Factor = 3.30576
Chromosome 8   position 19,824,563  (GRCh37) Explore rs1059611 on Ensembl!
Variant rs1059611 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.001 0.999
I25 Chronic ischaemic heart disease
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
I21 Acute myocardial infarction
0.000 0.005 0.995
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.013 0.987
I20 Angina pectoris
0.000 0.022 0.978
I24 Other acute ischaemic heart diseases
0.000 0.033 0.967
I20.9 Angina pectoris, unspecified
0.000 0.042 0.958
I21.9 Acute myocardial infarction, unspecified
0.000 0.052 0.948
I22 Subsequent myocardial infarction
0.000 0.056 0.944
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.087 0.913
I24.8 Other forms of acute ischaemic heart disease
0.000 0.110 0.890
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.111 0.889
I20.0 Unstable angina
0.000 0.128 0.872
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.141 0.859
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.179 0.821
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.182 0.817
I25.4 Coronary artery aneurysm
0.000 0.190 0.810
I25.2 Old myocardial infarction
0.000 0.242 0.758
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.265 0.735
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.280 0.720
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.716
I25.6 Silent myocardial ischaemia
0.000 0.284 0.716
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.286 0.713
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.290 0.710
I22.8 Subsequent myocardial infarction of other sites
0.000 0.312 0.688
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.344 0.656
I24.1 Dressler's syndrome
0.000 0.364 0.636
I20.1 Angina pectoris with documented spasm
0.000 0.373 0.627
I25.3 Aneurysm of heart
0.000 0.436 0.564
I20.8 Other forms of angina pectoris
0.000 0.452 0.548
I21.4 Acute subendocardial myocardial infarction
0.000 0.456 0.544
I25.5 Ischaemic cardiomyopathy
0.000 0.472 0.528
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.610 0.390
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.788 0.212
E78.0 Pure hypercholesterolaemia
0.000 0.810 0.190
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.818 0.182
E78.5 Hyperlipidaemia, unspecified
0.000 0.836 0.164
E78.2 Mixed hyperlipidaemia
0.000 0.837 0.163
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.843 0.157
E78.1 Pure hyperglyceridaemia
0.000 0.845 0.155
E78.4 Other hyperlipidaemia
0.000 0.864 0.136
E78.6 Lipoprotein deficiency
0.000 0.869 0.131
E78.3 Hyperchylomicronaemia
0.000 0.869 0.131
E78.8 Other disorders of lipoprotein metabolism
0.000 0.876 0.124
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.921 0.079
I77 Other disorders of arteries and arterioles
0.000 0.922 0.078
I71 Aortic aneurysm and dissection
0.000 0.924 0.076
I77.1 Stricture of artery
0.000 0.926 0.074
I72 Other aneurysm
0.000 0.931 0.069
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.931 0.069
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.934 0.066
I77.8 Other specified disorders of arteries and arterioles
0.000 0.934 0.066
I77.6 Arteritis, unspecified
0.000 0.934 0.066
I70 Atherosclerosis
0.000 0.936 0.064
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.936 0.064
Chapter IX Diseases of the circulatory system
0.000 0.936 0.064
I72.4 Aneurysm of artery of lower extremity
0.000 0.937 0.063
I71.0 Dissection of aorta [any part]
0.000 0.938 0.062
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.939 0.061
I72.3 Aneurysm of iliac artery
0.000 0.941 0.059
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.941 0.059
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.942 0.058
I77.5 Necrosis of artery
0.000 0.944 0.056
I77.4 Coeliac artery compression syndrome
0.000 0.944 0.056
I77.3 Arterial fibromuscular dysplasia
0.000 0.944 0.056
I77.2 Rupture of artery
0.000 0.944 0.056
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.945 0.055
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.945 0.055
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.945 0.055
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.945 0.055
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.945 0.055
I78 Diseases of capillaries
0.000 0.946 0.054
I77.0 Arteriovenous fistula, acquired
0.000 0.948 0.052
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.949 0.051
I72.8 Aneurysm of other specified arteries
0.000 0.950 0.050
I70.0 Atherosclerosis of aorta
0.000 0.950 0.050
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.950 0.050
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.950 0.050
I72.1 Aneurysm of artery of upper extremity
0.000 0.950 0.050
I74 Arterial embolism and thrombosis
0.000 0.951 0.049
I72.2 Aneurysm of renal artery
0.000 0.951 0.049
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.952 0.048
I79.1 Aortitis in diseases classified elsewhere
0.000 0.952 0.048
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.952 0.048
I70.9 Generalised and unspecified atherosclerosis
0.000 0.954 0.046
I70.8 Atherosclerosis of other arteries
0.000 0.954 0.046
I70.1 Atherosclerosis of renal artery
0.000 0.954 0.046
I00-I02 Acute rheumatic fever
0.000 0.954 0.046
I72.9 Aneurysm of unspecified site
0.000 0.954 0.046
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.955 0.045
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.958 0.042
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.960 0.040
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.960 0.040
I78.9 Disease of capillaries, unspecified
0.000 0.961 0.039
I78.8 Other diseases of capillaries
0.000 0.961 0.039
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.962 0.038
I74.5 Embolism and thrombosis of iliac artery
0.000 0.962 0.037
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.963 0.037
I72.0 Aneurysm of carotid artery
0.000 0.964 0.036
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.964 0.036
I74.8 Embolism and thrombosis of other arteries
0.000 0.965 0.035
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.965 0.035
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.965 0.035
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.965 0.035
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.966 0.033
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.966 0.033
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.966 0.033
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.966 0.033
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.966 0.033
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.966 0.033
I02 Rheumatic chorea
0.000 0.967 0.033
I01 Rheumatic fever with heart involvement
0.000 0.967 0.033
I00 Rheumatic fever without mention of heart involvement
0.000 0.967 0.033
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.969 0.031
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.969 0.031
I97.1 Other functional disturbances following cardiac surgery
0.000 0.971 0.029
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.972 0.028
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.972 0.028
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.972 0.028
I73 Other peripheral vascular diseases
0.000 0.973 0.027
I78.1 Naevus, nonneoplastic
0.000 0.973 0.026
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.974 0.025
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.975 0.025
I97.0 Postcardiotomy syndrome
0.000 0.975 0.025
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.975 0.025
I99 Other and unspecified disorders of circulatory system
0.000 0.975 0.025
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.976 0.024
I01.8 Other acute rheumatic heart disease
0.000 0.976 0.024
I01.2 Acute rheumatic myocarditis
0.000 0.976 0.024
I01.1 Acute rheumatic endocarditis
0.000 0.976 0.024
I01.0 Acute rheumatic pericarditis
0.000 0.976 0.024
I02.9 Rheumatic chorea without heart involvement
0.000 0.976 0.024
I02.0 Rheumatic chorea with heart involvement
0.000 0.976 0.024
I05-I09 Chronic rheumatic heart diseases
0.000 0.976 0.024
I73.8 Other specified peripheral vascular diseases
0.000 0.981 0.019
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.982 0.018
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.982 0.018
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.982 0.018
I98.0 Cardiovascular syphilis
0.000 0.982 0.018
I28 Other diseases of pulmonary vessels
0.001 0.982 0.017
I73.9 Peripheral vascular disease, unspecified
0.000 0.982 0.018
I06 Rheumatic aortic valve diseases
0.000 0.983 0.017
I09 Other rheumatic heart diseases
0.000 0.983 0.017
E70-E90 Metabolic disorders
0.000 0.983 0.017
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.983 0.016
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.985 0.015
I05 Rheumatic mitral valve diseases
0.000 0.986 0.014
I07 Rheumatic tricuspid valve diseases
0.000 0.986 0.014
E83.1 Disorders of iron metabolism
0.000 0.986 0.014
E86 Volume depletion
0.000 0.987 0.013
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.987 0.013
I28.1 Aneurysm of pulmonary artery
0.001 0.987 0.013
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.987 0.013
I27 Other pulmonary heart diseases
0.000 0.987 0.013
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.987 0.013
I06.8 Other rheumatic aortic valve diseases
0.000 0.987 0.013
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.987 0.013
I06.1 Rheumatic aortic insufficiency
0.000 0.987 0.013
I06.0 Rheumatic aortic stenosis
0.000 0.987 0.013
E88 Other metabolic disorders
0.000 0.987 0.013
E83 Disorders of mineral metabolism
0.000 0.987 0.013
I09.8 Other specified rheumatic heart diseases
0.000 0.987 0.012
I09.2 Chronic rheumatic pericarditis
0.000 0.987 0.012
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.987 0.012
I09.0 Rheumatic myocarditis
0.000 0.987 0.012
I26 Pulmonary embolism
0.002 0.987 0.011
I10-I15 Hypertensive diseases
0.000 0.987 0.012
E73 Lactose intolerance
0.000 0.988 0.012
E74 Other disorders of carbohydrate metabolism
0.000 0.988 0.012
I28.8 Other specified diseases of pulmonary vessels
0.001 0.988 0.012
E84 Cystic fibrosis
0.000 0.988 0.012
E79 Disorders of purine and pyrimidine metabolism
0.000 0.988 0.012
E77 Disorders of glycoprotein metabolism
0.000 0.988 0.012
E76 Disorders of glycosaminoglycan metabolism
0.000 0.988 0.012
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.988 0.012
E72 Other disorders of amino-acid metabolism
0.000 0.988 0.012
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.988 0.012
E70 Disorders of aromatic amino-acid metabolism
0.000 0.988 0.012
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.988 0.012
I09.9 Rheumatic heart disease, unspecified
0.000 0.988 0.012
R16.1 Splenomegaly, not elsewhere classified
0.012 0.988 0.000
K08.3 Retained dental root
0.000 0.988 0.012
I08 Multiple valve diseases
0.000 0.989 0.011
I05.1 Rheumatic mitral insufficiency
0.000 0.989 0.011
I05.2 Mitral stenosis with insufficiency
0.000 0.989 0.011
I05.8 Other mitral valve diseases
0.000 0.989 0.010
E85 Amyloidosis
0.000 0.990 0.010
I07.9 Tricuspid valve disease, unspecified
0.000 0.990 0.010
I07.8 Other tricuspid valve diseases
0.000 0.990 0.010
I07.2 Tricuspid stenosis with insufficiency
0.000 0.990 0.010
I07.0 Tricuspid stenosis
0.000 0.990 0.010
I08.8 Other multiple valve diseases
0.000 0.990 0.010
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.990 0.010
K62.0 Anal polyp
0.010 0.990 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.990 0.009
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.990 0.010
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.990 0.009
I27.1 Kyphoscoliotic heart disease
0.000 0.991 0.009
I11 Hypertensive heart disease
0.000 0.991 0.009
E88.2 Lipomatosis, not elsewhere classified
0.000 0.991 0.009
E73.9 Lactose intolerance, unspecified
0.000 0.991 0.009
E88.9 Metabolic disorder, unspecified
0.000 0.991 0.009
E88.8 Other specified metabolic disorders
0.000 0.991 0.009
E88.3 Tumour lysis syndrome
0.000 0.991 0.009
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.991 0.009
H04.2 Epiphora
0.000 0.991 0.009
K08.8 Other specified disorders of teeth and supporting structures
0.000 0.991 0.009
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.991 0.009
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.991 0.009
E83.8 Other disorders of mineral metabolism
0.000 0.991 0.009
E83.2 Disorders of zinc metabolism
0.000 0.991 0.009
E83.0 Disorders of copper metabolism
0.000 0.991 0.009
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.002 0.991 0.008
E73.8 Other lactose intolerance
0.000 0.991 0.009
E73.1 Secondary lactase deficiency
0.000 0.991 0.009
E73.0 Congenital lactase deficiency
0.000 0.991 0.009
I13 Hypertensive heart and renal disease
0.000 0.991 0.009
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.991 0.009
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.991 0.009
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.991 0.009
E74.2 Disorders of galactose metabolism
0.000 0.991 0.009
E74.1 Disorders of fructose metabolism
0.000 0.991 0.009
E74.0 Glycogen storage disease
0.000 0.991 0.009
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.991 0.009
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.991 0.009
E70.3 Albinism
0.000 0.991 0.009
E70.2 Disorders of tyrosine metabolism
0.000 0.991 0.009
E70.1 Other hyperphenylalaninaemias
0.000 0.991 0.009
E70.0 Classical phenylketonuria
0.000 0.991 0.009
E71.3 Disorders of fatty-acid metabolism
0.000 0.991 0.009
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.991 0.009
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.991 0.009
E71.0 Maple-syrup-urine disease
0.000 0.991 0.009
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.991 0.009
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.991 0.009
E72.5 Disorders of glycine metabolism
0.000 0.991 0.009
E72.4 Disorders of ornithine metabolism
0.000 0.991 0.009
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.991 0.009
E72.2 Disorders of urea cycle metabolism
0.000 0.991 0.009
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.991 0.009
E72.0 Disorders of amino-acid transport
0.000 0.991 0.009
E75.6 Lipid storage disorder, unspecified
0.000 0.991 0.009
E75.5 Other lipid storage disorders
0.000 0.991 0.009
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.991 0.009
E75.3 Sphingolipidosis, unspecified
0.000 0.991 0.009
E75.2 Other sphingolipidosis
0.000 0.991 0.009
E75.1 Other gangliosidosis
0.000 0.991 0.009
E75.0 GM2 gangliosidosis
0.000 0.991 0.009
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.991 0.009
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.991 0.009
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.991 0.009
E76.2 Other mucopolysaccharidoses
0.000 0.991 0.009
E76.1 Mucopolysaccharidosis, type II
0.000 0.991 0.009
E76.0 Mucopolysaccharidosis, type I
0.000 0.991 0.009
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.991 0.009
E77.8 Other disorders of glycoprotein metabolism
0.000 0.991 0.009
E77.1 Defects in glycoprotein degradation
0.000 0.991 0.009
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.991 0.009
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.991 0.009
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.991 0.009
E79.1 Lesch-Nyhan syndrome
0.000 0.991 0.009
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.991 0.009
E84.9 Cystic fibrosis, unspecified
0.000 0.991 0.009
E84.8 Cystic fibrosis with other manifestations
0.000 0.991 0.009
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.991 0.009
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.991 0.009
K08 Other disorders of teeth and supporting structures
0.000 0.991 0.009
I05.0 Mitral stenosis
0.000 0.991 0.009
I05.9 Mitral valve disease, unspecified
0.000 0.991 0.008
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.991 0.008
I08.9 Multiple valve disease, unspecified
0.000 0.991 0.008
H04 Disorders of lachrymal system
0.000 0.992 0.008
I27.9 Pulmonary heart disease, unspecified
0.000 0.992 0.008
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.992 0.008
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.992 0.008
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.992 0.008
I15 Secondary hypertension
0.000 0.992 0.008
E85.8 Other amyloidosis
0.000 0.992 0.008
E85.3 Secondary systemic amyloidosis
0.000 0.992 0.008
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.992 0.008
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.992 0.008
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.992 0.008
I27.2 Other secondary pulmonary hypertension
0.000 0.992 0.008
I27.0 Primary pulmonary hypertension
0.000 0.992 0.007
E85.4 Organ-limited amyloidosis
0.000 0.992 0.007
E83.4 Disorders of magnesium metabolism
0.000 0.993 0.007
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.993 0.007
E80.5 Crigler-Najjar syndrome
0.000 0.993 0.007
E80.3 Defects of catalase and peroxydase
0.000 0.993 0.007
E80.2 Other porphyria
0.000 0.993 0.007
E80.1 Porphyria cutanea tarda
0.000 0.993 0.007
E80.0 Hereditary erythropoietic porphyria
0.000 0.993 0.007
E83.3 Disorders of phosphorus metabolism
0.000 0.993 0.007
H04.8 Other disorders of lachrymal system
0.000 0.993 0.007
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.993 0.007
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.993 0.007
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.993 0.007
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.993 0.007
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.993 0.007
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.000 0.993 0.007
N39.4 Other specified urinary incontinence
0.000 0.993 0.007
K08.0 Exfoliation of teeth due to systemic causes
0.000 0.993 0.007
E89.2 Postprocedural hypoparathyroidism
0.000 0.993 0.007
L30.9 Dermatitis, unspecified
0.007 0.993 0.000
I07.1 Tricuspid insufficiency
0.000 0.994 0.006
E80.6 Other disorders of bilirubin metabolism
0.000 0.994 0.006
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.994 0.006
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.994 0.006
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.994 0.006
E89.5 Postprocedural testicular hypofunction
0.000 0.994 0.006
E89.4 Postprocedural ovarian failure
0.000 0.994 0.006
E89.1 Postprocedural hypoinsulinaemia
0.000 0.994 0.006
K08.2 Atrophy of edentulous alveolar ridge
0.000 0.994 0.006
H04.6 Other changes in lachrymal passages
0.000 0.994 0.006
H04.0 Dacryoadenitis
0.000 0.994 0.006
I08.0 Disorders of both mitral and aortic valves
0.000 0.994 0.006
E85.9 Amyloidosis, unspecified
0.000 0.994 0.006
H04.9 Disorder of lachrymal system, unspecified
0.000 0.994 0.006
E89.3 Postprocedural hypopituitarism
0.000 0.994 0.006
I15.1 Hypertension secondary to other renal disorders
0.000 0.994 0.006
K08.9 Disorder of teeth and supporting structures, unspecified
0.000 0.994 0.006
I15.8 Other secondary hypertension
0.000 0.994 0.006
I15.2 Hypertension secondary to endocrine disorders
0.000 0.994 0.006
I15.0 Renovascular hypertension
0.000 0.994 0.006
E28.3 Primary ovarian failure
0.006 0.994 0.000
H04.4 Chronic inflammation of lachrymal passages
0.000 0.994 0.005
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.994 0.005
E28 Ovarian dysfunction
0.006 0.994 0.000
E80.4 Gilbert's syndrome
0.000 0.994 0.005
C67 Malignant neoplasm of bladder
0.005 0.995 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.995 0.005
C67.1 Dome of bladder
0.005 0.995 0.000
E23 Hypofunction and other disorders of pituitary gland
0.005 0.995 0.000
H04.1 Other disorders of lachrymal gland
0.000 0.995 0.005
E23.2 Diabetes insipidus
0.005 0.995 0.000
E20-E35 Disorders of other endocrine glands
0.005 0.995 0.000
E28.2 Polycystic ovarian syndrome
0.005 0.995 0.000
E34 Other endocrine disorders
0.005 0.995 0.000
C67.4 Posterior wall of bladder
0.005 0.995 0.000
C67.6 Ureteric orifice
0.005 0.995 0.000
E23.7 Disorder of pituitary gland, unspecified
0.005 0.995 0.000
C67.9 Bladder, unspecified
0.005 0.995 0.000
C67.2 Lateral wall of bladder
0.005 0.995 0.000
E34.0 Carcinoid syndrome
0.005 0.995 0.000
S83.2 Tear of meniscus, current
0.000 0.995 0.005
W19.4 Street and highway
0.004 0.996 0.000
C67.0 Trigone of bladder
0.004 0.996 0.000
I15.9 Seconday hypertension, unspecified
0.001 0.996 0.004
I12 Hypertensive renal disease
0.000 0.996 0.004
C67.8 Overlapping lesion of bladder
0.004 0.996 0.000
E28.9 Ovarian dysfunction, unspecified
0.004 0.996 0.000
E28.8 Other ovarian dysfunction
0.004 0.996 0.000
E28.1 Androgen excess
0.004 0.996 0.000
E28.0 Oestrogen excess
0.004 0.996 0.000
I73.0 Raynaud's syndrome
0.000 0.996 0.004
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.004 0.996 0.000
C67.7 Urachus
0.004 0.996 0.000
E27 Other disorders of adrenal gland
0.004 0.996 0.000
E34.9 Endocrine disorder, unspecified
0.004 0.996 0.000
C67.5 Bladder neck
0.004 0.996 0.000
C67.3 Anterior wall of bladder
0.004 0.996 0.000
E23.6 Other disorders of pituitary gland
0.004 0.996 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.004 0.996 0.000
E23.1 Drug-induced hypopituitarism
0.004 0.996 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.004 0.996 0.000
E34.8 Other specified endocrine disorders
0.004 0.996 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.996 0.004
E29 Testicular dysfunction
0.004 0.996 0.000
E20 Hypoparathyroidism
0.004 0.996 0.000
E23.0 Hypopituitarism
0.004 0.996 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.004 0.996 0.000
E32 Diseases of thymus
0.004 0.996 0.000
E31 Polyglandular dysfunction
0.004 0.996 0.000
E30 Disorders of puberty, not elsewhere classified
0.004 0.996 0.000
E25 Adrenogenital disorders
0.004 0.996 0.000
E26 Hyperaldosteronism
0.004 0.996 0.000
O14.9 Preeclampsia, unspecified
0.004 0.996 0.000
E27.8 Other specified disorders of adrenal gland
0.004 0.996 0.000
E34.5 Androgen resistance syndrome
0.004 0.996 0.000
E34.4 Constitutional tall stature
0.004 0.996 0.000
E34.3 Short stature, not elsewhere classified
0.004 0.996 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.004 0.996 0.000
E34.1 Other hypersecretion of intestinal hormones
0.004 0.996 0.000
E24 Cushing's syndrome
0.004 0.996 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.996 0.004
E22 Hyperfunction of pituitary gland
0.004 0.996 0.000
E61.1 Iron deficiency
0.000 0.996 0.004
L30 Other dermatitis
0.004 0.996 0.000
O70.1 Second degree perineal laceration during delivery
0.003 0.997 0.000
T17.2 Foreign body in pharynx
0.003 0.997 0.000
E05.9 Thyrotoxicosis, unspecified
0.003 0.997 0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.003 0.997 0.000
I95 Hypotension
0.000 0.997 0.003
H02.0 Entropion and trichiasis of eyelid
0.003 0.997 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.003 0.997 0.000
E27.5 Adrenomedullary hyperfunction
0.003 0.997 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.003 0.997 0.000
E27.1 Primary adrenocortical insufficiency
0.003 0.997 0.000
E27.0 Other adrenocortical overactivity
0.003 0.997 0.000
E27.9 Disorder of adrenal gland, unspecified
0.003 0.997 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.000 0.997 0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.003 0.997 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.000 0.997 0.003
E29.1 Testicular hypofunction
0.003 0.997 0.000
E29.9 Testicular dysfunction, unspecified
0.003 0.997 0.000
E29.8 Other testicular dysfunction
0.003 0.997 0.000
E29.0 Testicular hyperfunction
0.003 0.997 0.000
E20.9 Hypoparathyroidism, unspecified
0.003 0.997 0.000
E20.8 Other hypoparathyroidism
0.003 0.997 0.000
E20.1 Pseudohypoparathyroidism
0.003 0.997 0.000
E20.0 Idiopathic hypoparathyroidism
0.003 0.997 0.000
L30.8 Other specified dermatitis
0.003 0.997 0.000
O70.9 Perineal laceration during delivery, unspecified
0.003 0.997 0.000
E25.9 Adrenogenital disorder, unspecified
0.003 0.997 0.000
E25.8 Other adrenogenital disorders
0.003 0.997 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.003 0.997 0.000
E30.9 Disorder of puberty, unspecified
0.003 0.997 0.000
E30.8 Other disorders of puberty
0.003 0.997 0.000
E30.1 Precocious puberty
0.003 0.997 0.000
E30.0 Delayed puberty
0.003 0.997 0.000
E31.9 Polyglandular dysfunction, unspecified
0.003 0.997 0.000
E31.8 Other polyglandular dysfunction
0.003 0.997 0.000
E31.1 Polyglandular hyperfunction
0.003 0.997 0.000
E31.0 Autoimmune polyglandular failure
0.003 0.997 0.000
E32.9 Disease of thymus, unspecified
0.003 0.997 0.000
E32.8 Other diseases of thymus
0.003 0.997 0.000
E32.1 Abscess of thymus
0.003 0.997 0.000
E32.0 Persistent hyperplasia of thymus
0.003 0.997 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.003 0.997 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.003 0.997 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.003 0.997 0.000
E26.9 Hyperaldosteronism, unspecified
0.003 0.997 0.000
E26.8 Other hyperaldosteronism
0.003 0.997 0.000
E26.1 Secondary hyperaldosteronism
0.003 0.997 0.000
E27.2 Addisonian crisis
0.003 0.997 0.000
F06.7 Mild cognitive disorder
0.003 0.997 0.000
E24.8 Other Cushing's syndrome
0.003 0.997 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.003 0.997 0.000
E24.3 Ectopic ACTH syndrome
0.003 0.997 0.000
E24.2 Drug-induced Cushing's syndrome
0.003 0.997 0.000
E24.1 Nelson's syndrome
0.003 0.997 0.000
E24.0 Pituitary-dependent Cushing's disease
0.003 0.997 0.000
E26.0 Primary hyperaldosteronism
0.003 0.997 0.000
E22.0 Acromegaly and pituitary gigantism
0.003 0.997 0.000
E22.1 Hyperprolactinaemia
0.003 0.997 0.000
E24.9 Cushing's syndrome, unspecified
0.003 0.997 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.003 0.997 0.000
E22.8 Other hyperfunction of pituitary gland
0.003 0.997 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.000 0.997 0.003
E05 Thyrotoxicosis [hyperthyroidism]
0.003 0.997 0.000
L30.5 Pityriasis alba
0.003 0.997 0.000
L30.4 Erythema intertrigo
0.003 0.997 0.000
L30.3 Infective dermatitis
0.003 0.997 0.000
L30.2 Cutaneous autosensitisation
0.003 0.997 0.000
L30.1 Dyshidrosis [pompholyx]
0.003 0.997 0.000
L30.0 Nummular dermatitis
0.003 0.997 0.000
S51.0 Open wound of elbow
0.003 0.997 0.000
E21.3 Hyperparathyroidism, unspecified
0.003 0.997 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.003 0.997 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.003 0.997 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.000 0.997 0.003
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.003 0.997 0.000
I95.8 Other hypotension
0.000 0.997 0.002
I12.9 Hypertensive renal disease without renal failure
0.000 0.997 0.002
S83.7 Injury to multiple structures of knee
0.000 0.997 0.002
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.000 0.997 0.002
S83.3 Tear of articular cartilage of knee, current
0.000 0.997 0.002
S83.1 Dislocation of knee
0.000 0.997 0.002
S83.0 Dislocation of patella
0.000 0.997 0.002
W19.1 Residential institution
0.003 0.997 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.002 0.997 0.000
E21.4 Other specified disorders of parathyroid gland
0.002 0.997 0.000
E21.2 Other hyperparathyroidism
0.002 0.997 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.002 0.998 0.000
O70 Perineal laceration during delivery
0.002 0.998 0.000
W19 Unspecified fall
0.002 0.998 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.002 0.998 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.000 0.998 0.002
H52.1 Myopia
0.002 0.998 0.000
I95.0 Idiopathic hypotension
0.000 0.998 0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.002 0.998 0.000
I51.9 Heart disease, unspecified
0.000 0.998 0.002
E05.8 Other thyrotoxicosis
0.002 0.998 0.000
E05.5 Thyroid crisis or storm
0.002 0.998 0.000
E05.4 Thyrotoxicosis factitia
0.002 0.998 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.002 0.998 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.002 0.998 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.998 0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.002 0.998 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.002 0.998 0.000
O70.2 Third degree perineal laceration during delivery
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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